Typing tool
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Typing tool
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Complete norovirus genomes
| OR546399 | GII.8 | |
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| GII.P8 |
ORF1: 1..5100
ORF2: 5081..6694
ORF3: 6694..7467
LOCUS OR546399 7486 bp RNA linear VRL 09-JAN-2024
DEFINITION Norovirus GII isolate GII/Hu/TH/2023/GII.8[P8]/B10039 nonstructural
polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes, complete cds.
ACCESSION OR546399
VERSION OR546399.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7486)
AUTHORS Chuchaona,W., Vongpunsawad,S., Lawtongkum,W., Thepnarong,N. and
Poovorawan,Y.
TITLE Acute Gastroenteritis Associated with Norovirus GII.8[P8],
Thailand, 2023
JOURNAL Emerg Infect Dis 30 (1), 194-197 (2024)
PUBMED 38147526
REFERENCE 2 (bases 1 to 7486)
AUTHORS Chuchaona,W., Vongpunsawad,S., Lorthongkham,W., Thepnarong,N. and
Poovorawan,Y.
TITLE Direct Submission
JOURNAL Submitted (13-SEP-2023) Department of Pediatrics, Center of
Excellence in Clinical Virology, Chulalongkorn, Phayathai, Bangkok,
Bangkok 10330, Thailand
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7486
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="GII/Hu/TH/2023/GII.8[P8]/B10039"
/isolation_source="rectal swab"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Thailand"
/collection_date="14-Jun-2023"
/note="genotype: GII.8[P8]"
gene 1..5100
/gene="ORF1"
CDS 1..5100
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="WMY97781.1"
/translation="MKMASNDATAAAGNFNIANNSENTPPPIKEEASVLSNVKVGFKK
ILGAVPKQPKPPEVKTKDQPRVLVNGKALEVPPPPPNGEDVVYYNSKDDTVYGLPNLT
TVSCEGENLPYTVPPLSEREHRAAPEPLPGTILEMWDGEFYHYAIYVSGGKAIGVHKP
PAAISLATIQLTPISLYWRPVYVPNYLVHPDTLKSLAGEKFPYTAFNNNCYNFCCWVL
DLKDSWLNRRSITRTTGFFKPYQSWNKKPLPTVDDGKIKKVANAVLCALGSLFSKPIK
DLIGKLKPLNFLNLLASCDWTFSGVVETVILVAELFGVFWTPPDVSNFIASLVGDFEL
QGPEDLAVELVPIIMGGVGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVM
KWFFPKKEEKAEMETLRAIEDAVLDMEAIGNNHLTALLKDRDSLLTYMKTLDLEEEKA
RKLSTKSSSPDIVGTINAILARIAAARSLLHRAKEEMYSRPRPVVVMISGRPGVGKTH
MARHLAKSVAGTMSGDQRVGLIPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALALQE
LADTCPVTLNCDRIENKGKMFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEA
PTIEKAKKDFPGQPDMWKEHFKADFSHLKLTLAPQGGFDKNGNTPHGKGTMKTLTQGS
LTARVAGLVHERKDEFQLQGGELQVYNFDTNKVSAFRKLAADNNYGFLETMRVGSSLK
DVKTVEDLKCALKSVSFKECEIIYRNVKYRVSSDGCGKVSIEKLADNNSQTTREIITA
VTRLRQARARYYISCFQDLVYTLLQVAGASFVINRIVKKFNWERWVKAPETDEPTPSN
DKPDTEEEWEIAPKDVDSEGKKGKNKKGRGRKHTAFSSKGLSDEEYDEFKRLREEKQG
RYTIEEYLQDRDRYYEELAVARATEENFCEEEEIKIRQRIFRPTKKQRKEERGVLGLV
TGADIRKRKPDDFQPKGRLWADDSRSVDYNEKIEFEAPPSVWSRIVPLGTGWGFWVSS
NLLITTTHVLPKGVKELFGVDIKQVQVHKSGEFCRFRFPKPVRPDVSGLVLEEGAPEG
TVCSVLIKRSTGEMIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGD
CGCPYIYKRGNDIVVAGVHTAAARGGNTVICATQGPDGEAVLEGGEDHGTYCGAPILA
PGKAPKLSTKTKFWRSSPDSLPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEEAKKTVMNVLEQTIEPAKPWTYSQACASLDKTTSSGSPHHVRKNEHW
NGESFTGPLADQASKANLMYEEGKHMDPMYTAALKDELVKTDKIYKKIKKRLLWGSDL
GTMVRCARAFGGLLDSMKESCISLPCRVGMNINEDGPLIFEKHSKYTYHYDADYSRWD
STQQRAVLSAAMEVMVKFSAEPELAQVVAEDLLAPSRLDVGDFVISVQEGLPSGVPCT
SQWNSIAHWILTLSAMSEVSGLSPEVVQANSCFSFYGDDEIVSTDINLDPEKLTRKLR
EYGLVPTRPDKTEGPLVITQDLNGLTFLRRTIVRDPAGWFGKLDRDSILRQLYWTRGP
NHENPFESMIPHSQRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQE
AMFRWMRFSDLSTWEGDRNLAPENVNEDGVE"
mat_peptide 1..1005
/gene="ORF1"
/product="p48"
mat_peptide 1006..2103
/gene="ORF1"
/product="NTPase"
mat_peptide 2104..2625
/gene="ORF1"
/product="p22"
mat_peptide 2626..3024
/gene="ORF1"
/product="VPg"
mat_peptide 3025..3567
/gene="ORF1"
/product="Pro"
mat_peptide 3568..5097
/gene="ORF1"
/product="RdRp"
gene 5081..6694
/gene="ORF2"
CDS 5081..6694
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="WMY97782.1"
/translation="MKMASNDAAPSNDGAAGLVPEINHEVMAIEPVAGASLAAPVVGQ
LNIIDPWIRNNFVQAPAGEFTVSPRNAPGEFLLDLELGPELNPYLAHLARMYNGHAGG
MEVQIVLAGNAFTAGKILFAVIPPGFPYENLSPAQLTMCPHVVVDVRQLEPILLPMPD
IRNTFFHYNQSNGPKLRLVAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFEFNFLVPP
SVESKTKAFTLPILKISEMTNSRFPIPVDQMYTSRNENIVVQPQNGRVTLDGELQGTT
TLQPVSICGFRGTLQTRLADQPNYTYQVHLENLDGSPVDPTDEVPAPLGTPDFQAQLF
GVVSQRSSDNATRAHEARVNTNDPTFAPQIAQVRFKSPSHDFFDNEPIKFTPVGISVD
SENGYNQWLLPRYGGHLTNNTHLAPSVSPMFPGEQILFFRSFMPGASGHTDGAIDCLL
PQEWVAHFYQEAATAQTDVALIRFVNPDSGRVLFEGKLHKQGFITISNSGDHPIVMPA
NGYFRFEAWVNQFYSLAPVGTGSGRRRVQ"
gene 6694..7467
/gene="ORF3"
CDS 6694..7467
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="WMY97783.1"
/translation="MAGAFLAGLAGDVVSSGIGSLINAGANAVNQKVEYDFNRQLQEA
SFKHDKEMLNAQINATTKLQRDMIAIKQGVLTAGGFSPTDAARGSINAPTTKILDWNG
SRYWAPGSMRTTAYSGNFTSQGVKQPTPIVRSVKPQVQQSPAPSSVYSVGSVRSQSTQ
STQLTGSGTVSRAPTPSTTTTLSRTSEWVRSQNDRLSPFMGGALQTAFITPPSSKASS
SSGTVSTVPKEILDSWTPAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 atgaagatgg cgtctaacga cgctaccgct gccgctggca actttaacat tgccaacaac
61 agtgaaaaca ctccccctcc cattaaggaa gaggcgagtg tcctatccaa cgtaaaagtt
121 ggatttaaga aaatattggg ggctgtgccc aagcagccca agccaccaga agtgaaaacc
181 aaagatcagc ccagggtgct ggtcaatggt aaggccttgg aggtaccgcc cccaccacca
241 aatggtgaag acgtggtcta ctataacagc aaggatgaca ccgtgtacgg tctaccaaat
301 ctaacaacag tcagctgtga aggtgaaaac cttccgtaca cagtcccccc tctcagcgag
361 agagagcaca gggcagcacc agaaccatta cctggtacca tactagagat gtgggatggt
421 gaattctacc attatgcgat atatgtctct ggtggcaagg ccataggggt gcacaaaccc
481 ccagctgcaa tcagccttgc cactatccag cttacgccta tatcgcttta ctggaggccc
541 gtttatgtcc ctaattactt ggtccaccct gacacactca agagcttagc cggtgaaaaa
601 ttcccataca ccgcatttaa caacaactgt tacaatttct gttgctgggt tcttgacctg
661 aaagattcgt ggctcaaccg cagatcaata actagaacaa ccggtttctt caagccttat
721 cagtcctgga acaagaaacc acttccgacg gtggatgatg gaaaaatcaa gaaagtcgcc
781 aatgcagtcc tatgtgccct tggttcacta ttctcaaaac ctattaagga cttgatcggg
841 aagctgaaac cactgaattt cttgaatctc ctcgcctcgt gcgactggac cttctccgga
901 gtggttgaga ccgtcatact agttgctgag ctgtttggtg tgttttggac cccccccgac
961 gtgtcgaatt tcatcgcgtc actcgtcggg gattttgagc tgcaaggtcc agaggattta
1021 gctgtggagt tggtgccgat catcatgggc ggtgtcggga tggtgctggg attcaccgcc
1081 gagaagatcg gccgaatgct atcatcggct gcatcgaccc ttagggcctg taaagaccta
1141 ggtaactacg cccttgacat acttaaattg gtcatgaagt ggttcttccc aaagaaggag
1201 gaaaaggcag agatggaaac cttgagggct atagaggatg ctgtcttaga catggaggcg
1261 attgggaata accacctcac tgctctgttg aaagacaggg acagcctcct aacttacatg
1321 aagactctag accttgaaga agaaaaggcg agaaagctat ccacaaaatc atcgtcccct
1381 gacattgtgg gtactatcaa tgccatacta gccagaattg ctgcggctag gtctctcctg
1441 cacagagcca aagaagaaat gtacagcaga cctaggcctg tcgtggtgat gatatcaggg
1501 agaccagggg ttggtaaaac ccatatggct agacacctcg ccaagagtgt ggcgggcacc
1561 atgagtggtg accaaagggt gggcctcatc ccccgcaatg gagttgacca ttgggatgcc
1621 tataggggag aacgagtcgt cttgtgggac gactatggta tgggcaaccc agtgaaggac
1681 gccctcgctc tgcaagaact agcagacact tgtccagtca ctctcaattg tgacaggata
1741 gagaacaaag ggaagatgtt tgacagcgag gtaataatca taacaactaa tttggccaac
1801 cccgccccgc ttgattatgt caactttgaa gcttgttccc gtagaatcga cttcctcgtc
1861 tacgcagaag ccccaactat tgagaaggcg aagaaggatt ttcccgggca accagacatg
1921 tggaaggagc acttcaaagc agacttctcc cacctcaaac tcacactggc cccgcaaggc
1981 ggttttgaca agaacggcaa cacgccacat gggaagggga ctatgaagac cttaacacag
2041 ggttccctca cagcaagagt ggctgggctc gtgcacgaaa ggaaagatga gtttcagtta
2101 cagggtggag agttgcaggt ctacaatttt gacacaaaca aggtatcggc tttcaggaag
2161 cttgctgcag ataacaacta tgggttcctg gagacaatga gagtcggctc ctcactcaag
2221 gacgtcaaga cagtggaaga tcttaaatgt gctcttaaga gtgtcagttt caaagaatgt
2281 gaaataatct acaggaatgt caagtaccgc gtatcatcag acggttgcgg taaggtcagc
2341 atagagaaac tggcagataa caactcccaa acaaccagag agattatcac ggccgtcact
2401 agactacgac aggctcgtgc taggtactac atcagttgct tccaagacct agtctacaca
2461 ctcttgcagg ttgccggagc ctcatttgtc attaacagaa tagtcaagaa gttcaactgg
2521 gaacgatggg tcaaagctcc agaaacagat gaacccacac caagtaatga caagcccgac
2581 actgaagagg aatgggagat cgcccccaaa gatgtggact ctgagggtaa aaagggaaag
2641 aacaagaagg gcaggggacg taagcacact gcgttctcca gcaaagggct cagtgatgag
2701 gagtatgatg aattcaaaag actaagggaa gagaaacagg gccgctacac aatagaggag
2761 tacctccagg acagggaccg gtactatgaa gagctggcag tggcccgggc cactgaggag
2821 aacttctgtg aagaggaaga gataaagatc aggcaaagga tattccgccc caccaaaaag
2881 cagaggaagg aggagcgtgg ggttctggga ctcgtcacag gagcagacat caggaaacgg
2941 aaacccgatg acttccaacc aaaaggaaga ttgtgggcag atgactctag gagcgtcgac
3001 tacaatgaga agatcgagtt tgaggctcct cctagcgtct ggtcaagaat cgtcccgctt
3061 ggaactggtt gggggttctg ggtctcatcc aacttattaa ttaccaccac acatgtgctg
3121 cccaaaggtg ttaaagagct ttttggggtg gatatcaaac aagtccaagt tcacaaatca
3181 ggcgaatttt gcagattcag gttcccaaaa ccagtgaggc cagatgtctc tgggttggtg
3241 ttagaagaag gggcccccga aggcacagtg tgctctgttc tcatcaagag gtctacagga
3301 gagatgatcc ccctcgcagt taggatgggc acccacgcct ctatgaagat tcaggggcgc
3361 actgttggcg gccagatggg catgctgctc actggagcca acgctaagaa catggatttg
3421 ggtaccggcc ccggggattg tggttgcccg tacatataca agaggggcaa tgacatcgta
3481 gtggccggcg tccacacagc agcggcgcgc gggggcaaca cagtcatctg cgcaacccaa
3541 ggacctgatg gtgaggcagt gttggaaggg ggagaggacc acggtactta ctgtggagcc
3601 ccaatactgg cccctggcaa agcgccgaag ctcagcacaa agaccaagtt ttggcgctca
3661 tcccctgatt cccttccccc tgggacgtat gaaccagctt accttggggg caaggacccc
3721 cgtgtggaga aagggccgtc actccaacaa gtgatgcgag accaactcaa acccttcaca
3781 gaacccaggg gcaagccacc taggccgtca gtgctggagg aagccaagaa gacagtcatg
3841 aatgtactgg agcagaccat agaaccagct aagccatgga cctactctca agcctgtgct
3901 tcactggata aaacaacatc cagtggcagt cctcaccatg tcagaaagaa tgaacactgg
3961 aacggggagt cttttactgg gcctcttgca gatcaagcct caaaagccaa cctaatgtat
4021 gaggaaggta aacatatgga ccctatgtac acagcagccc tcaaagacga gctggtaaaa
4081 accgacaaaa tctacaagaa aatcaagaag aggttgttgt gggggtctga tctggggaca
4141 atggtgaggt gtgctcgagc gtttggagga ttgctcgaca gcatgaaaga gagttgcatc
4201 tccttacctt gtagggttgg catgaacata aatgaagatg gaccactcat atttgaaaaa
4261 cactccaaat acacctatca ctatgatgct gattactcta ggtgggactc aacacaacag
4321 agggccgtac tgagtgcagc tatggaggta atggtgaagt tctctgctga gccggaactg
4381 gctcaggtgg ttgccgaaga cctccttgca cccagccgtc ttgacgtggg tgactttgtc
4441 atctccgttc aagaaggtct cccatcgggt gtcccctgca catcacagtg gaactcaatt
4501 gctcattgga ttttgactct tagtgctatg tctgaggtct ctggtctttc ccctgaggtt
4561 gtgcaagcca actcctgttt ctcattctat ggggatgatg agatagtcag cacagacata
4621 aatctggacc cagaaaaact caccaggaaa ctgagggagt atggcctcgt cccaacaagg
4681 ccagataaaa ctgaaggccc acttgtgatt actcaggatt tgaatggtct cacatttctg
4741 aggcgaacca tagtgcggga ccccgcaggc tggtttggaa aactggaccg tgactccatt
4801 ctaaggcagt tatactggac tagaggaccc aaccatgaga acccctttga aagcatgatt
4861 cctcactccc agagagcaac ccagttaatg gcccttcttg gagaagcctc gctgcatggt
4921 ccccagtttt acaagaaggt gagtaaaatg gtaatcaacg agatcaagag tggtggtctg
4981 gagttttacg tgcccagaca ggaggccatg tttagatgga tgagattttc agacctcagc
5041 acgtgggagg gcgatcgcaa tctggctccc gagaatgtga atgaagatgg cgtcgaatga
5101 cgcagctcca tcgaatgatg gcgcggctgg cctcgtacca gagatcaacc atgaggtcat
5161 ggccatagag cctgtagcag gagcttcttt agcagctcct gttgtaggac aacttaatat
5221 aattgatccc tggattagaa ataactttgt acaagcccct gctggagaat tcactgtttc
5281 gcctaggaat gctccaggtg aatttttatt agatttagag ttaggtccag aattgaatcc
5341 ttaccttgct caccttgcac gcatgtataa tgggcatgca ggtggtatgg aggtgcagat
5401 agtgcttgct gggaatgcgt tcacagcggg caaaatattg tttgcagtta taccgcctgg
5461 attcccctat gaaaatttgt cacctgcaca attgaccatg tgcccacatg tagtggtgga
5521 tgtgaggcag cttgaaccaa tcttgctgcc catgccagac atccgcaaca cattcttcca
5581 ttacaaccag agcaacgggc caaaacttag attagtagct atgctttaca cacccctaag
5641 ggctaataat gctggtgatg atgtcttcac agtttcctgc agggttttga ctcgcccatc
5701 accagatttt gaatttaatt ttcttgtccc cccatccgtt gaatctaaga ctaaagcttt
5761 cacccttcca attcttaaga tatctgagat gacaaattca agatttccca taccagttga
5821 ccagatgtac actagtagga atgaaaatat agttgttcaa ccacaaaatg gtagagtgac
5881 acttgatgga gagttacagg gcacaaccac actccaaccg gtgtccattt gtggcttccg
5941 agggacgctg cagaccaggc tggcagatca accaaattac acataccaag tgcatcttga
6001 gaatttggac ggctcacccg ttgacccgac agatgaagtt ccagcccccc tggggacacc
6061 agattttcag gcccagctat ttggagttgt cagccaaagg agtagtgata atgccaccag
6121 ggcacatgag gccagggtca acaccaacga tcctaccttc gcgccccaga tcgcccaggt
6181 gcgtttcaaa tcaccatccc acgacttctt tgacaatgag cccatcaaat tcacaccagt
6241 tggaatcagt gttgatagcg aaaatggtta caaccaatgg ctcctaccca ggtatggtgg
6301 acacctgaca aacaacaccc acctggcccc ctctgtgtcc ccaatgttcc ccggcgagca
6361 gattctcttc ttccgctcgt tcatgccagg tgccagtggt cacactgatg gtgctattga
6421 ctgcctttta ccacaagagt gggttgccca cttctatcag gaggccgcaa ctgcgcaaac
6481 agatgtggct ctgatcagat ttgtgaaccc cgactcaggc agagtgctat ttgaagggaa
6541 gttgcacaag cagggtttta taaccatctc caacagtggg gaccacccca ttgttatgcc
6601 tgctaatgga tacttcagat ttgaggcatg ggtcaaccaa ttttactctc tcgcccccgt
6661 gggaactgga agtgggcgca gaagagttca ataatggctg gagcttttct tgctggtctg
6721 gctggtgatg tggtgtcctc tggcatcggg tcactcatca atgcaggtgc taatgcagtg
6781 aaccaaaagg ttgaatatga cttcaatagg caactccaag aagcttcttt taaacatgac
6841 aaggagatgt tgaatgctca aattaatgcc acaaccaaat tgcaaaggga catgattgcc
6901 attaagcagg gggttttgac cgctggcggc ttttccccca ctgacgctgc aaggggttcc
6961 atcaatgctc caaccaccaa aattcttgac tggaacgggt ctaggtactg ggcaccagga
7021 tcaatgagaa caacagcgta ctctggcaat ttcacatcac agggagttaa gcagcccaca
7081 cccattgtta ggtctgtaaa acctcaagta cagcaatctc ctgccccttc ttctgtttat
7141 tctgtaggtt ctgttaggtc acaatcaaca caatcaaccc aactaacagg gtcagggact
7201 gtatcaaggg cacccacccc ctcaacaacc acaacattgt ccagaacaag tgagtgggtg
7261 aggagccaga atgataggtt gagccccttt atgggaggcg cactccagac agctttcatc
7321 acgcccccat cgagtaaggc ttcatcctca tcaggaacag tctcaaccgt tcctaaagaa
7381 attttggact cctggactcc tgcatttaac acgcgcaggc agccgctctt cgctcacata
7441 cgtaagcgag gggagtcacg ggcttagtga aaagaatgat ttggtt
//