Typing tool
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Typing tool
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Complete norovirus genomes
| OR546397 | GII.8 | |
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| GII.P8 |
ORF1: 1..5100
ORF2: 5081..6694
ORF3: 6694..7467
LOCUS OR546397 7486 bp RNA linear VRL 09-JAN-2024
DEFINITION Norovirus GII isolate GII/Hu/TH/2023/GII.8[P8]/B9256 nonstructural
polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes, complete cds.
ACCESSION OR546397
VERSION OR546397.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7486)
AUTHORS Chuchaona,W., Vongpunsawad,S., Lawtongkum,W., Thepnarong,N. and
Poovorawan,Y.
TITLE Acute Gastroenteritis Associated with Norovirus GII.8[P8],
Thailand, 2023
JOURNAL Emerg Infect Dis 30 (1), 194-197 (2024)
PUBMED 38147526
REFERENCE 2 (bases 1 to 7486)
AUTHORS Chuchaona,W., Vongpunsawad,S., Lorthongkham,W., Thepnarong,N. and
Poovorawan,Y.
TITLE Direct Submission
JOURNAL Submitted (13-SEP-2023) Department of Pediatrics, Center of
Excellence in Clinical Virology, Chulalongkorn, Phayathai, Bangkok,
Bangkok 10330, Thailand
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7486
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="GII/Hu/TH/2023/GII.8[P8]/B9256"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Thailand"
/collection_date="27-Feb-2023"
/note="genotype: GII.8[P8]"
gene 1..5100
/gene="ORF1"
CDS 1..5100
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="WMY97775.1"
/translation="MKMASNDATAAAGNFNIANNSENTPPPIKEEASVLSNVKVGFKK
ILGAVPKQPKPPEVKTKDQPRVLVNDKALEVPPPPPNGEDVVYYNSKDDTVHGLPNLT
TVSCEGENLPYTVPPLSEREHRAAPEPVPGTILEMWDGEFYHYAIYVSGGKAIGVHKP
PAAISLATIELTPISLYWRPVYVPNYLVHPDTLKSLAGEKFPYTAFSNNCYNFCCWVL
DLKDSWLNRRSITRTTGFFKPYQSWNKKPLPTVDDGKIKKVANAVLCALGSLFSKPIK
DLIGKLKPLNFLNLLASCDWTFSGVVETVILVAELFGVFWTPPDVSNFIASLVGDFEL
QGPEDLAVELVPIIMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVM
KWFFPKKEEKAEMETLRAIEDAVLDMEAIGNNHLTALLKDRDSLLTYMKTLDLEEEKA
RKLSTKSSSPDIVGTINAILARIAAARSLLHRAKEEMYSRPRPVVVMISGRPGVGKTH
MARHLAKSVAGTMSGDQRVGLIPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALALQE
LADTCPVTLNCDRIENKGKMFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEA
PTIEKAKKDFPGQPDMWKEHFKADFSHLKLTLAPQGGFDKNGNTPHGKGTMKTLTQGS
LTARVAGLVHERKDEFQLQGGELQVYNFDTNKVSAFRKLAADNNYGFLETMRVGSSLK
DVKTVEDLKCALKSVSFKECEIIYRNVKYRISSDGCGKVSIEKLADNNSQTTREIITA
VTRLRQARARYYISCFQDLVYTLLQVAGASFVINRIVKKFNWERWVKAPETDEPTPNN
DKPDTEEEWEIAPKDVDSEGKKGKNKKGRGRKHTAFSSKGLSDEEYDEFKRLREEKQG
RYTIEEYLQDRDRYYEELAVARATEENFCEEEEIKIRQRIFRPTKKQRKEERGVLGLV
TGADIRKRKPDDFQPKGKLWADDSRSVDYNEKIEFEAPPSVWSRIVPLGTGWGFWVSS
NLLITTTHVLPKGIKELFGVDIKQVQVHKSGEFCRFRFPKPVRPDVSGLVLEEGAPEG
TVCSVLIKRSTGEMIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGD
CGCPYIYKRGNDIVVAGVHTAAARGGNTVICATQGPDGEAVLEGGEDHGTYCGAPILA
PGKAPKLSTKTKFWRSSPDSLPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEEAKKTVMNVLEQTIEPAKPWTYSQACASLDKTTSSGSPHHVRKNEHW
NGESFTGPLADQASKANLMYEEGKHMDPMYTAALKDELVKTDKIYKKIKKRLLWGSDL
GTMVRCARAFGGLLDSMKESCISLPCRVGMNINEDGPLIFEKHSKYTYHYDADYSRWD
STQQRAVLSAAMEVMVKFSAEPELAQVVAEDLLAPSRLDVGDFVISVQEGLPSGVPCT
SQWNSIAHWILTLSAMSEVSGLSPEVVQANSCFSFYGDDEIVSTDINLDPEKLTRKLR
EYGLVPTRPDKTEGPLVITQDLNGLTFLRRTIVRDPAGWFGKLDRDSILRQLYWTRGP
NHENPFESMIPHSQRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQE
AMFRWMRFSDLSTWEGDRNLAPENVNEDGVE"
mat_peptide 1..1005
/gene="ORF1"
/product="p48"
mat_peptide 1006..2103
/gene="ORF1"
/product="NTPase"
mat_peptide 2104..2625
/gene="ORF1"
/product="p22"
mat_peptide 2626..3024
/gene="ORF1"
/product="VPg"
mat_peptide 3025..3567
/gene="ORF1"
/product="Pro"
mat_peptide 3568..5097
/gene="ORF1"
/product="RdRp"
gene 5081..6694
/gene="ORF2"
CDS 5081..6694
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="WMY97776.1"
/translation="MKMASNDAAPSNDGAAGLVPEINHEVMAIEPVAGASLAAPVVGQ
LNVIDPWIRNNFVQAPAGEFTVSPRNAPGEFLLDLELGPELNPYLAHLARMYNGHAGG
MEVQIVLAGNAFTAGKILFAVIPPGFPYENLSPAQLTMCPHVVVDVRQLEPILLPMPD
IRNTFFHYNQSNGPKLRLVAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFEFNFLVPP
SVESKTKAFTLPILKISEMTNSRFPIPVDQMYTSRNENIVVQPQNGRVTLDGELQGTT
TLQPVSICGFRGTLQTRLADQPNYTYQVHLENLDGSPVDPTDEVPAPLGTPDFQAQLF
GVVSQRSSDNATRAHEARVNTNDPTFAPQIAQVRFKSPSHDFFDNEPIKFTPVGISVD
SENSYNQWLLPRYGGHLTNNTHLAPSVSPMFPGEQILFFRSFMPGASGHTDGAIDCLL
PQEWVAHFYQEAATAQTDVALIRFVNPDTGRVLFEGKLHKQGFITISNSGDHPIVMPA
NGYFRFEAWVNQFYSLAPVGTGSGRRRVQ"
gene 6694..7467
/gene="ORF3"
CDS 6694..7467
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="WMY97777.1"
/translation="MAGAFLAGLAGDVVTSGIGSLINAGANAVNQKVEYDFNRQLQEA
SFKHDKEMLNAQINATTKLQKDMIAIKQGVLIAGGFSPTDAARGSINAPTTKILDWNG
SRYWAPGSMRTTAYSGNFISQGVKQPTPIVKSVKPQVQQSPAPSSVYSVGSVRSQSTQ
STQLTGSGTVSRASTPSTTTTLSRTSEWVRSQNDRLSPFMGGALQTAFITPPSSKASS
SSGTVSTVPKDILDSWTPAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 atgaagatgg cgtctaacga cgctaccgct gccgctggca actttaacat tgccaacaac
61 agtgaaaaca ctccccctcc cattaaggaa gaggcgagtg tcctatccaa cgtaaaagtt
121 ggatttaaga aaatattggg ggctgtgcct aagcagccca agccaccaga agtgaaaacc
181 aaagatcagc ccagggtgct ggtcaatgat aaggccttgg aggtaccgcc cccgccacca
241 aatggtgaag acgtggttta ctataacagc aaggatgaca ccgtgcacgg tttaccaaat
301 ctaacaacag tcagctgtga aggtgaaaac ctcccgtaca cagtcccccc tctcagcgag
361 agagagcata gggcagcacc agaaccagta cctggcacca tactagagat gtgggatggt
421 gagttctacc attatgcgat atatgtctct ggtggcaagg ccataggggt gcacaaaccc
481 ccagccgcaa tcagccttgc cactatcgag cttacaccta tatcgcttta ctggaggccc
541 gtttatgtcc ctaattactt ggtccaccct gatacactca agagcttagc tggtgaaaaa
601 tttccataca ctgcatttag caataattgt tacaatttct gttgctgggt tcttgacctg
661 aaagactcgt ggctcaaccg cagatcaata actagaacaa ccggtttctt caagccttat
721 caatcctgga acaagaaacc acttccgaca gtggatgatg gaaaaatcaa gaaagtcgcc
781 aatgcagtcc tgtgtgccct tggttcatta ttctcaaaac ctattaagga cttgatcggg
841 aagctgaagc cattgaattt cttgaatctc ctcgcttcgt gcgactggac cttctctgga
901 gtggttgaga ccgtcatact ggttgctgaa ctgtttggtg tgttttggac cccccccgac
961 gtgtcgaatt tcatcgcgtc actcgtcggg gattttgagc tgcagggtcc agaggattta
1021 gctgtggagt tggtgccgat catcatgggc ggtatcggga tggtgctggg atttaccgcc
1081 gagaagatcg gccgaatgct atcatcagct gcatcgaccc ttagggcctg taaagaccta
1141 ggtaattacg cccttgacat actcaaatta gtcatgaagt ggttcttccc aaagaaggag
1201 gaaaaggcag agatggaaac cttgagggct atagaagatg ctgtcttaga catggaggcg
1261 attggaaata accacctcac tgctctgttg aaagacaggg acagcctcct aacttacatg
1321 aagactctag accttgaaga agaaaaggca agaaaactgt ccacaaaatc atcgtcccct
1381 gacatcgtgg gtactatcaa tgccatacta gccagaattg ctgcggctag gtctctcctg
1441 cacagagcca aagaagaaat gtacagcaga cccaggcctg tcgtggtgat gatatcagga
1501 agaccagggg ttggtaaaac ccatatggct agacacctcg ccaagagtgt ggcgggtacc
1561 atgagcggtg accaaagggt gggcctcatc cctcgcaatg gagttgacca ttgggatgcc
1621 tataggggag aacgagttgt cttgtgggac gactatggca tgggtaaccc agtgaaggat
1681 gctctcgctc tgcaggaact agcagacact tgcccagtca ctctcaattg tgacaggata
1741 gagaacaagg ggaagatgtt tgacagcgag gtaataatta taacaactaa tttggccaac
1801 cccgccccgc ttgattatgt caactttgaa gcttgttccc gcagaatcga cttcctcgtc
1861 tacgcagaag ctccgaccat tgagaaggcg aagaaggatt ttcccgggca accagacatg
1921 tggaaggagc acttcaaagc agacttctct cacctcaaac tcacactggc cccgcaaggt
1981 ggttttgaca agaacggcaa cacgccacat gggaagggga ctatgaagac cttaacacag
2041 ggttccctca cagcaagagt ggctgggctt gtgcacgaaa ggaaagatga gtttcagtta
2101 cagggtggag agttgcaggt ctacaatttt gacacaaaca aggtatcggc tttcaggaag
2161 cttgctgcag acaacaacta tggattcctg gagacaatga gagtcggctc ctcactcaag
2221 gacgtcaaga cagtggaaga tcttaaatgt gcccttaaga gtgtcagttt caaagaatgt
2281 gaaataatct acaggaatgt caagtaccgc atatcatcag acggttgcgg taaggtcagc
2341 atagagaaac tggcagataa caattcccaa acaaccagag agattatcac ggccgtcact
2401 agactacgac aggctcgtgc taggtactac atcagctgct tccaagacct agtctacaca
2461 cttttgcagg ttgccggagc ctcatttgtt attaacagaa tagtcaagaa gttcaactgg
2521 gaacgatggg tcaaggctcc agaaacagat gaacccacac caaataacga caagcccgac
2581 actgaagagg agtgggagat cgcccccaaa gatgtagact ctgagggtaa gaaggggaag
2641 aacaagaagg gcaggggacg taagcacact gcgttctcca gcaaagggct tagtgatgag
2701 gagtatgatg aattcaaaag actaagggaa gagaagcagg gccgctacac aatagaggag
2761 tacctccagg acagggatcg gtactatgaa gagctggcag tggcccgggc cactgaggag
2821 aacttctgtg aagaggaaga gataaagatc aggcaaagga tattccgccc caccaaaaag
2881 cagaggaagg aggagcgcgg ggttctggga cttgtcacag gagcagacat caggaaacgg
2941 aaacccgatg acttccaacc aaaaggaaaa ttgtgggcag atgattctag gagtgttgac
3001 tacaatgaga agatcgagtt tgaagctcct cctagcgtct ggtcaagaat cgtcccgctt
3061 ggaactggtt ggggattctg ggtctcatcc aacttattaa ttaccaccac acatgtgctg
3121 cctaaaggta tcaaagagct ttttggggtg gacatcaaac aagtccaagt tcacaaatca
3181 ggtgaatttt gcagattcag gttcccaaaa ccagtgagac cagatgtctc tgggttggtg
3241 ttagaagaag gggcccccga aggcacagtg tgctctgttc tcatcaagag gtccacagga
3301 gagatgatcc cccttgcagt tagaatgggc acccacgcct ctatgaagat tcaggggcgg
3361 actgttggcg gccagatggg catgctactc actggagcca acgctaagaa catggatttg
3421 ggtaccggcc ctggggattg tggttgcccg tatatataca agaggggcaa tgacatcgtg
3481 gtggccggcg tccacacagc agcggcgcgc gggggcaaca cggtcatctg cgcaacccaa
3541 ggacctgatg gtgaggcagt gctggagggg ggggaggacc acggtactta ctgtggagcc
3601 ccaatactgg cccctggtaa agcgccaaag ctcagcacaa aaaccaagtt ttggcgctca
3661 tcccctgatt cccttccccc tgggacgtat gaaccagctt accttggggg caaggacccc
3721 cgtgtggaga aagggccctc actccaacaa gtgatgcgag accaactcaa acccttcaca
3781 gaacccaggg gcaagccacc taggccgtca gtgctggagg aagccaagaa aacagtcatg
3841 aatgtgctgg agcagaccat agaaccagct aagccatgga cctactctca agcctgtgct
3901 tcattggata aaacaacatc cagtggcagt cctcaccatg tcaggaagaa tgaacactgg
3961 aacggggagt ctttcactgg gcctcttgca gatcaagcct caaaagccaa cctgatgtat
4021 gaggaaggta aacatatgga ccctatgtac acagcagccc tcaaagatga gctggtaaaa
4081 actgacaaaa tctacaagaa aatcaagaag aggttgttgt ggggatctga tctggggaca
4141 atggtgaggt gtgctcgagc gtttggagga ttgctcgaca gcatgaaaga gagttgcatt
4201 tccttacctt gtagggttgg catgaatata aatgaagatg gaccactcat atttgaaaaa
4261 cattccaaat atacctatca ctatgatgct gactactcta ggtgggattc aacacaacag
4321 agggctgtac tgagtgcagc tatggaggta atggtgaagt tctccgctga accggaactg
4381 gctcaggtgg ttgccgaaga cctccttgca cccagccgtc ttgacgtggg tgactttgtc
4441 atctccgtcc aagaaggcct cccatcgggt gtcccctgca cgtcacagtg gaactcaatt
4501 gctcattgga ttttgactct tagtgccatg tctgaggtct ctggtctttc ccctgaggtt
4561 gtgcaagcca attcctgttt ctcattctat ggggatgatg agatagtcag cacagacata
4621 aacctggacc cagaaaaact caccaggaaa ctgagggagt atggcctcgt cccaacaagg
4681 ccagataaaa ctgagggccc acttgtgatt actcaggatt tgaatggtct cacatttctg
4741 aggcgaacca tagtgcggga ccccgcaggc tggtttggaa aactggaccg tgattctatt
4801 ctaaggcagc tatactggac cagaggaccc aatcatgaga acccctttga aagcatgatt
4861 ccccactccc agagagcaac ccaattaatg gcacttcttg gggaagcctc attgcatggt
4921 ccccagttct acaagaaggt gagtaaaatg gtcattaatg agatcaagag tggtggtctg
4981 gagttttacg tgcccagaca ggaggccatg tttagatgga tgagattttc agacctcagc
5041 acgtgggagg gcgatcgcaa tctggctccc gagaatgtga atgaagatgg cgtcgaatga
5101 cgcagctcca tcgaatgatg gcgcggctgg cctcgtacca gagatcaacc atgaggtcat
5161 ggccatagaa cctgttgcag gagcctcttt agcagctcct gtcgtaggac aacttaatgt
5221 aattgatccc tggattagaa ataattttgt acaagcccct gctggagaat tcactgtttc
5281 gcctaggaac gctccaggtg aatttttgtt agatctagag ttaggtccag agttgaaccc
5341 ttatcttgct caccttgcac gcatgtataa tgggcatgca ggtggtatgg aggtgcagat
5401 agtgcttgct gggaatgcgt tcacagcggg caaaatcctg tttgcagtca taccgcctgg
5461 attcccctat gaaaatttgt cacctgcaca attgaccatg tgcccacatg tagtggtgga
5521 tgtgaggcag cttgaaccaa tcttgctgcc catgccagac atccgcaata cattcttcca
5581 ttacaaccag agcaatgggc caaaacttag attagtagct atgctttaca cacccctaag
5641 ggctaacaat gctggtgatg atgttttcac agtttcctgc agggttttga ctcgcccatc
5701 accagacttt gaattcaatt ttcttgtccc cccatctgtt gaatctaaga ctaaagcttt
5761 cacccttcca attcttaaga tatctgagat gacaaattca agatttccca taccagttga
5821 tcagatgtac actagtagga atgaaaatat agttgttcaa ccacaaaatg gcagggtgac
5881 acttgatgga gagttgcagg gcacaaccac actccaaccg gtgtccattt gtggcttccg
5941 agggacgctg caaaccaggc tggcagatca accaaattac acataccaag tgcaccttga
6001 gaatttggac ggctcacccg tcgacccgac ggatgaagtt ccagcccccc tgggtacacc
6061 agatttccag gcccagctat ttggagttgt cagccaaagg agtagtgata atgccaccag
6121 ggcacatgag gctagggtca acaccaacga tcctaccttc gcgccccaga tcgcccaagt
6181 gcgtttcaaa tcaccatccc acgacttctt tgacaatgaa cccatcaaat tcacaccagt
6241 tggaatcagt gttgatagcg aaaatagcta caaccaatgg ctcctaccca ggtatggtgg
6301 acacctgaca aacaacaccc acctagcccc ctctgtgtcc ccaatgttcc ccggcgagca
6361 gattctcttt ttccgctcgt tcatgccagg tgccagtggt cacactgatg gtgctattga
6421 ctgcctttta ccacaagagt gggttgccca cttctatcag gaggccgcaa ctgcgcaaac
6481 agatgtggct ctgatcagat ttgtgaaccc cgacacaggc agagtgctat ttgaagggaa
6541 gttgcacaag cagggtttta taaccatctc caacagcggg gaccacccca ttgttatgcc
6601 tgctaatgga tacttcaggt ttgaggcatg ggtcaaccaa ttttactctc tcgcccccgt
6661 gggaactgga agtgggcgca ggagagttca ataatggctg gagcttttct tgctggtctg
6721 gctggtgatg tggtgacctc tggcattggg tcgctcatca atgcaggtgc taatgcagtg
6781 aaccaaaagg ttgaatatga tttcaatagg caactccaag aagcttcttt taaacatgac
6841 aaagagatgt tgaatgctca aattaatgcc acaaccaaat tgcaaaagga catgattgcc
6901 attaagcagg gggttttgat cgctggcggc ttttccccca ctgatgctgc aaggggttcc
6961 atcaatgctc caaccaccaa aattcttgac tggaacggat ctaggtattg ggcaccagga
7021 tcaatgagaa caacagcata ctctggcaat ttcatatcac agggagttaa gcagcccaca
7081 cccattgtta agtctgtgaa accccaagta cagcaatctc ctgccccttc ctctgtttat
7141 tctgtaggtt ctgttaggtc acaatcaaca caatcaaccc aattaacagg gtcagggact
7201 gtatcaagag catccacccc ctcaacaacc acaacactgt ctagaacaag tgagtgggtg
7261 aggagccaga atgataggtt gagccccttt atgggaggtg cactccagac agctttcatc
7321 acgcccccat cgagtaaggc ttcatcctca tcaggaacag tctcaaccgt ccctaaagat
7381 attttggact cctggactcc tgcatttaac acgcgcaggc agccgctctt cgctcacata
7441 cgtaagcgag gggagtcacg ggcttagtga aaagaatgat ttggtt
//