Typing tool
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Typing tool
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Complete norovirus genomes
| OR546396 | GII.8 | |
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|---|---|---|---|
| GII.P8 |
ORF1: 1..5100
ORF2: 5081..6694
ORF3: 6694..7467
LOCUS OR546396 7486 bp RNA linear VRL 09-JAN-2024
DEFINITION Norovirus GII isolate GII/Hu/TH/2023/GII.8[P8]/B9202 nonstructural
polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes, complete cds.
ACCESSION OR546396
VERSION OR546396.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7486)
AUTHORS Chuchaona,W., Vongpunsawad,S., Lawtongkum,W., Thepnarong,N. and
Poovorawan,Y.
TITLE Acute Gastroenteritis Associated with Norovirus GII.8[P8],
Thailand, 2023
JOURNAL Emerg Infect Dis 30 (1), 194-197 (2024)
PUBMED 38147526
REFERENCE 2 (bases 1 to 7486)
AUTHORS Chuchaona,W., Vongpunsawad,S., Lorthongkham,W., Thepnarong,N. and
Poovorawan,Y.
TITLE Direct Submission
JOURNAL Submitted (13-SEP-2023) Department of Pediatrics, Center of
Excellence in Clinical Virology, Chulalongkorn, Phayathai, Bangkok,
Bangkok 10330, Thailand
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7486
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="GII/Hu/TH/2023/GII.8[P8]/B9202"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Thailand"
/collection_date="22-Feb-2023"
/note="genotype: GII.8[P8]"
gene 1..5100
/gene="ORF1"
CDS 1..5100
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="WMY97772.1"
/translation="MKMASNDATAAAGNFNIANNSENTPPPIKEEASVLSNVKVGFKK
ILGAVPKQPKPPEVKTKDQPRVLVNGKALEVPPPPPNGEDVVYYNSKDDTVHGLPNLT
TVSCEGENLPYTVPPLSEREHRAAPEPLPGTILEMWDGEFYHYAIYVSGGKAIGVHKP
PAAISLATIELTPISLYWRPVYVPNYLVHPDTLKSLAGEKFPYTAFSNNCYNFCCWVL
DLKDSWLNRRSITRTTGFFKPYQSWNKKPLPTVDDGKIKKVANAVLCALGSLFSKPIK
DLIGKLKPLNFLNLLASCDWTFSGVVETVILVAELFGVFWTPPDVSNFIASLVGDFEL
QGPEDLAVELVPIIMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVM
KWFFPKKEEKAEMETLRAIEDAVLDMEAIGNNHLTALLKDRDSLLTYMKTLDLEEEKA
RKLSTKSSSPDIVGTINAILARIAAARSLLHRAKEEMYSRPRPVVVMISGRPGVGKTH
MARHLAKSVAGTMSGDQRVGLIPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALALQE
LADTCPVTLNCDRIENKGKMFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEA
PTIEKAKKDFPGQPDMWKEHFKADFSHLKLTLAPQGGFDKNGNTPHGKGTMKTLTQGS
LTARVAGLVHERKDEFQLQGGELQVYNFDTNKVSAFRKLAADNNYGFLETMRVGSSLK
DVKTVEDLKCALKSVSFKECEIIYRNVKYRISSDGCGKVSIEKLADNNSQTTREIITA
VTRLRQARARYYISCFQDLVYTLLQVAGASFVINRIVKKFNWERWVKAPETDEPTPSN
DKPDTEEEWEIAPKDVDSEGKKGKNKKGRGRKHTAFSSKGLSDEEYDEFKRLREEKQG
RYTIEEYLQDRDRYYEELAVARATEENFCEEEEIKIRQRIFRPTKKQRKEERGVLGLV
TGADIRKRKPDDFQPKGRLWADDSRSVDYNEKIEFEAPPSVWSRIVPLGTGWGFWVSS
NLLITTTHVLPKGIKELFGVDIKQVQVHKSGEFCRFRFPKPVRSDVSGLVLEEGAPEG
TVCSVLIKRSTGEMIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGD
CGCPYIYKRGNDIVVAGVHTAAARGGNTVICATQGPDGEAVLEGGEDHGTYCGAPILA
PGKAPKLSTKTKFWRSSPDSLPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEEAKKTVMNVLEQTIEPAKPWTYSQACASLDKTTSSGSPHHVRKNEHW
NGESFTGPLADQASKANLMYEEGKHMDPMYTAALKDELVKTDKIYKKIKKRLLWGSDL
GTMVRCARAFGGLLDSMKESCISLPCRVGMNINEDGPLIFEKHSKYTYHYDADYSRWD
STQQRAVLSAAMEVMVKFSAEPELAQVVAEDLLAPSRLDVGDFVISVQEGLPSGVPCT
SQWNSIAHWILTLSAMSEVSGLSPEVVQANSCFSFYGDDEIVSTDINLDPEKLTRKLR
EYGLVPTRPDKTEGPLVITQDLNGLTFLRRTIVRDPAGWFGKLDRDSILRQLYWTRGP
NHENPFESMIPHSQRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQE
AMFRWMRFSDLSTWEGDRNLAPENVNEDGVE"
mat_peptide 1..1005
/gene="ORF1"
/product="p48"
mat_peptide 1006..2103
/gene="ORF1"
/product="NTPase"
mat_peptide 2104..2625
/gene="ORF1"
/product="p22"
mat_peptide 2626..3024
/gene="ORF1"
/product="VPg"
mat_peptide 3025..3567
/gene="ORF1"
/product="Pro"
mat_peptide 3568..5097
/gene="ORF1"
/product="RdRp"
gene 5081..6694
/gene="ORF2"
CDS 5081..6694
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="WMY97773.1"
/translation="MKMASNDAAPSNDGAAGLVPEINHEVMAIEPVAGASLAAPVVGQ
LNIIDPWIRNNFVQAPAGEFTVSPRNAPGEFLLDLELGPELNPYLAHLARMYNGHAGG
MEVQIVLAGNAFTAGKILFAVIPPGFPYENLSPAQLTMCPHVVVDVRQLEPILLPMPD
IRNTFFHYNQSNGPKLRLVAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFEFNFLVPP
SVESKTKAFTLPILKISEMTNSRFPIPVDQMYTSRNENIVVQPQNGRVTLDGELQGTT
TLQPVSICGFRGTLQARLADQPNYTYQVHLENLDGSPVDPTDEVPAPLGTPDFQAQLF
GVVSQRSSDNATRAHEARVNTNDPTFAPQIAQVRFKSPSHDFFDNEPIKFTPVGISVD
SENGYNQWLLPRYGGHLTNNTHLAPSVSPMFPGEQILFFRSFMPGASGHTDGAIDCLL
PQEWVAHFYQEAATAQTDVALIRFVNPDSGRVLFEGKLHKQGFITISNSGDHPIVMPA
NGYFRFEAWVNQFYSLAPVGTGSGRRRVQ"
gene 6694..7467
/gene="ORF3"
CDS 6694..7467
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="WMY97774.1"
/translation="MAGAFLAGLAGDVVSSGIGSLINAGANAVNQKVEYDFNRQLQEA
SFKHDKEMLNAQINATTKLQRDMIAIKQGVLTAGGFSPTDAARGSINAPTTKILDWNG
SRYWAPGSMRTTAYSGNFTSQGVKQPTPIVRSVKPQVQQSPAPSSVYSVGSVRSQSTQ
STQLTGSGTASRAPTPSTTTALSRTSEWVRSQNDRLSPFMGGALQTAFITPPSSKASS
SSGTVSTVPREILDSWTPAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 atgaagatgg cgtctaacga cgctaccgct gccgctggca actttaacat tgccaacaac
61 agtgaaaaca ctccccctcc cattaaggaa gaggcgagtg tcctatccaa cgtaaaggtt
121 ggatttaaga aaatattggg ggctgtgccc aagcagccca aaccaccaga agtgaaaacc
181 aaagatcagc ccagggtgct ggtcaatggt aaggccttgg aggtaccgcc cccacctcca
241 aatggtgaag acgtggttta ctataacagc aaggatgaca ccgtgcacgg tctaccaaat
301 ttaacaacag tcagctgtga aggtgaaaac ctcccgtaca cagtcccccc tctcagcgag
361 agagagcaca gggcagcacc agaaccatta cctggtacca tactagagat gtgggatggt
421 gagttctacc attatgcgat atatgtctct ggtggcaagg ccataggggt acacaaaccc
481 ccagctgcaa tcagccttgc cactattgag cttacaccta tatcgcttta ctggaggccc
541 gtttatgtcc ctaattactt ggtccaccct gacacactca agagcttagc cggtgaaaaa
601 ttcccataca ccgcatttag caacaattgt tacaatttct gttgctgggt tcttgacctg
661 aaagactcgt ggctcaaccg cagatcaata accagaacaa ccggtttctt caagccttat
721 cagtcctgga acaagaaacc acttccgacg gtggatgatg gaaaaatcaa gaaagtcgcc
781 aatgcagtcc tgtgtgccct tggttcacta ttttcaaaac ctattaagga cttgattggg
841 aagctgaaac cactgaattt cttgaatctc ctcgcctcgt gcgattggac cttctccgga
901 gtggttgaga ccgtcatact agttgctgag ctatttggtg tgttttggac cccccccgat
961 gtgtcgaatt tcatcgcgtc actcgtcggg gattttgagc tgcagggtcc agaggattta
1021 gctgtggagt tggtgccgat catcatgggc ggtattggga tggtgctggg attcaccgct
1081 gagaagatcg gccgaatgct atcatcggct gcatcgaccc ttagggcctg taaagaccta
1141 ggtaactacg cccttgacat acttaaattg gtcatgaagt ggttcttccc aaagaaggag
1201 gaaaaggcag agatggaaac cttgagggct atagaggatg ctgtcttaga catggaggcg
1261 attggaaata accacctcac tgctctgttg aaagacagag acagcctcct aacttacatg
1321 aagactctgg accttgaaga agaaaaggcg agaaagctgt ccacaaagtc atcgtcccct
1381 gacatcgtgg gtactatcaa tgccatacta gccagaattg ctgcggctag gtctctcctg
1441 cacagagcca aagaagaaat gtacagcaga cctaggcctg tcgtggtgat gatatcaggg
1501 agaccagggg ttggtaaaac ccatatggct agacacctcg ccaagagtgt ggcgggtacc
1561 atgagtggtg accaaagggt gggcctcatc ccccgcaatg gagttgacca ttgggatgcc
1621 tataggggag aacgagttgt cttgtgggac gactatggta tgggcaaccc agtgaaggat
1681 gccctcgctt tgcaagaact agcagacact tgtccggtca ctctcaattg tgacaggata
1741 gagaacaagg ggaagatgtt tgatagcgag gtaataatca taacaaccaa tttggccaac
1801 cccgccccgc ttgattatgt caactttgaa gcttgttccc gtagaatcga ctttctcgtc
1861 tacgcagaag ccccaactat tgagaaggcg aagaaggatt ttcccgggca accagatatg
1921 tggaaggagc atttcaaagc agacttctcc cacctcaaac tcacactggc cccgcaaggc
1981 ggttttgaca agaacggcaa cacgccacat gggaagggga ctatgaagac cttaacacag
2041 ggttccctca cagcaagagt ggctgggctt gtgcacgaaa ggaaagatga gtttcagtta
2101 caaggtggag agttgcaggt ctacaatttt gacacaaaca aggtgtcggc tttcaggaag
2161 cttgctgcag acaacaacta tgggttcctg gagacaatga gagtcggctc ctcactcaag
2221 gacgttaaga cagtggaaga tcttaagtgt gctcttaaga gtgtcagttt caaagaatgt
2281 gaaataatct acaggaatgt caagtaccgc atatcatcag acggttgcgg taaggtcagc
2341 atagagaaac tggcagataa caactcccaa acaaccagag agattatcac ggccgtcact
2401 agactacgac aggctcgtgc taggtactac atcagctgct tccaagacct agtctataca
2461 ctcttgcagg ttgccggagc ctcatttgtc attaacagaa tagttaagaa gttcaactgg
2521 gaacgatggg tcaaggctcc agaaacagat gaacccacac caagtaatga caagcccgac
2581 actgaagagg aatgggagat cgcccccaaa gatgtggact ctgagggtaa gaaggggaag
2641 aacaagaagg gcaggggacg caagcacact gcgttctcca gcaaggggct tagtgatgag
2701 gagtatgatg aattcaaaag actaagggaa gagaaacagg gccgctacac aatagaggag
2761 tacctccagg acagggaccg gtactatgaa gagctggcag tggcccgggc cactgaggaa
2821 aacttctgtg aagaggaaga gataaagatc aggcaaagga tattccgccc caccaaaaag
2881 cagagaaagg aggagcgcgg ggttctggga ctcgtcacag gagcagacat caggaaacgg
2941 aaacccgatg acttccaacc aaaaggaaga ttgtgggcag atgactctag gagcgtcgac
3001 tacaatgaga agatcgagtt tgaggctcct cctagcgtct ggtcaaggat cgtcccgctt
3061 ggaactggtt gggggttctg ggtctcatcc aacttactaa ttaccaccac acatgtgctg
3121 cccaaaggca ttaaagagct ttttggggtg gatatcaaac aggtccaagt tcacaaatca
3181 ggtgaatttt gcagatttag gttcccaaaa ccagtgaggt cagatgtctc tgggttggta
3241 ttagaagaag gggcccccga aggcacagtg tgctctgttc tcatcaagag gtctacagga
3301 gagatgatcc cccttgcagt taggatgggc acccacgcct ctatgaagat tcaggggcgc
3361 actgttggcg gacagatggg catgctgctc actggagcca acgctaagaa catggatttg
3421 ggtaccggcc ccggggattg tggttgcccg tacatataca agaggggcaa tgacatcgtg
3481 gtggccggcg tccacacagc agcagcgcgc gggggcaaca cggtcatctg cgcaacccaa
3541 ggacctgatg gtgaggcagt gttggaaggg ggagaggacc acggtactta ctgtggagcc
3601 ccaatactgg cccctggtaa agcgccgaaa ctcagcacaa agactaagtt ctggcgctca
3661 tcccctgatt cccttccccc tgggacgtat gaaccagctt accttggggg caaggacccc
3721 cgtgtggaga aaggaccgtc actccagcaa gtgatgcgag accaactcaa acccttcaca
3781 gaacccaggg gcaagccacc taggccgtca gtgctggagg aagctaagaa gacagtcatg
3841 aatgtactgg agcagaccat agaaccagct aagccatgga cctactctca agcctgtgct
3901 tcattggata aaacaacatc cagtggcagt cctcaccatg tcaggaagaa tgaacactgg
3961 aatggggagt cttttactgg gcctcttgca gaccaagcct caaaagccaa cctgatgtat
4021 gaggaaggta aacatatgga ccctatgtac acagcagccc tcaaagacga gctggtgaaa
4081 actgacaaaa tctacaagaa aatcaagaag aggttgttgt gggggtctga tctggggaca
4141 atggtgaggt gtgctcgagc gtttggagga ttgctcgaca gcatgaaaga gagttgcatc
4201 tccttacctt gtagggttgg catgaacata aatgaagatg gaccactcat atttgagaaa
4261 cattccaaat acacctatca ctatgatgct gattactcta ggtgggactc aacacaacag
4321 agggctgtac tgagtgcagc catggaggtg atggtgaagt tctccgctga gccggaactg
4381 gctcaggtgg ttgccgaaga cctccttgca cccagccgtc ttgacgtggg tgactttgtc
4441 atctccgttc aagaaggtct cccatcgggt gtcccctgca cgtcacagtg gaactcaatt
4501 gctcattgga ttctgaccct tagtgctatg tctgaggtct ctggtctttc ccctgaggtt
4561 gtgcaagcca actcctgttt ctcattctat ggggatgatg agatagtcag cacagacata
4621 aatctagacc cagaaaaact caccaggaaa ttgagggagt atggcctcgt cccaacaagg
4681 ccagataaga ctgagggccc acttgtgatt actcaggatt tgaatggtct cacatttctg
4741 aggcgaacca tagtgcggga ccccgcaggc tggtttggaa aactggaccg tgattccatt
4801 ctgaggcagt tgtactggac cagaggaccc aaccatgaga acccctttga aagcatgatt
4861 cctcactccc agagagcaac tcagttaatg gcccttcttg gagaagcctc gctgcatggt
4921 ccccagtttt acaagaaggt gagcaaaatg gtaatcaatg agatcaagag tggtggtctg
4981 gagttttacg tgcccagaca ggaggccatg tttagatgga tgagattttc agacctcagc
5041 acgtgggagg gcgatcgcaa tctggctccc gagaatgtga atgaagatgg cgtcgaatga
5101 cgcagctcca tcgaatgatg gcgcggctgg cctcgtacca gagatcaacc atgaggtcat
5161 ggccatagag cctgttgcag gagcttcttt agcagctcct gtcgtaggac aacttaatat
5221 aattgatccc tggattagaa ataattttgt acaagcccct gctggagaat tcactgtttc
5281 gcctaggaat gctccaggtg aatttctatt agatctagag ttaggtccag aattgaaccc
5341 ttatcttgcc caccttgcac gcatgtataa cgggcatgca ggtggcatgg aggtgcagat
5401 agtgcttgct gggaatgcgt tcacagcggg caaaatactg tttgcagtca taccgcctgg
5461 attcccctat gaaaatttgt cacctgcaca attgaccatg tgcccacatg tagtggtgga
5521 tgtgaggcag cttgaaccaa tcttgctgcc catgccagac atccgcaaca cattcttcca
5581 ttacaaccag agcaacgggc caaaacttag attagtagct atgctttaca cacccctaag
5641 ggctaacaat gctggtgatg atgtcttcac agtttcctgc agggttttga ctcgcccatc
5701 accagatttt gaattcaact ttcttgtccc cccatctgtt gaatctaaga ctaaagcttt
5761 cacccttcca attcttaaga tatctgagat gacaaattca aggtttccca taccagttga
5821 ccagatgtac actagtagga atgagaatat agttgttcaa ccacaaaatg gtagagtgac
5881 acttgatgga gaattacagg gcacaaccac actccaaccg gtgtccattt gtggcttccg
5941 agggacgctg caggccaggc tggcagatca accaaattac acataccagg tgcaccttga
6001 gaatttggac ggctcacccg tcgacccgac agatgaagtt ccagcccccc tggggacacc
6061 agattttcag gcccagctat ttggagttgt cagccaaagg agtagtgaca atgccaccag
6121 ggcacatgag gccagggtca acaccaacga ccctaccttc gcgccccaga tcgcccaggt
6181 gcgtttcaaa tcaccatccc acgacttctt tgacaatgaa cccatcaaat tcacaccagt
6241 tggaatcagt gttgatagcg aaaatggtta caaccagtgg ctcctaccca ggtatggtgg
6301 acacctgaca aacaacaccc acctggcccc ctctgtgtcc ccgatgttcc ccggcgagca
6361 gattctcttc ttccgctcgt tcatgccagg tgccagtggt cacaccgatg gtgctattga
6421 ctgcctttta ccacaagagt gggttgccca cttctatcag gaagccgcaa ctgcgcaaac
6481 agatgtggct ctgatcagat ttgtgaaccc cgactcaggc agagtgctat ttgaagggaa
6541 gttgcacaag cagggtttta taaccatctc caacagcggg gaccacccca ttgttatgcc
6601 tgctaatgga tacttcaggt ttgaggcatg ggtcaaccaa ttttactctc tcgcccccgt
6661 gggaactgga agtgggcgca gaagagttca ataatggctg gagcttttct tgctggtcta
6721 gctggtgatg tggtgtcctc tggcatcggg tcactcatta atgcaggtgc taatgcagtg
6781 aaccaaaagg ttgaatatga cttcaatagg caactccaag aagcttcttt taaacatgat
6841 aaggagatgt tgaatgctca aattaatgcc acaaccaaat tgcaaaggga catgattgct
6901 atcaagcagg gggttttgac cgctggcggc ttttccccca ctgatgctgc aaggggctcc
6961 atcaatgctc caaccaccaa aattcttgac tggaacgggt ctaggtactg ggcaccagga
7021 tcaatgagaa caacagcgta ctctggcaat ttcacatcac agggagttaa gcagcccaca
7081 cccattgtta gatctgtgaa accccaagtg cagcaatctc ctgccccttc ttctgtttat
7141 tctgtaggtt ctgttaggtc acaatcaaca caatcaaccc aattaacagg gtcagggact
7201 gcatcaaggg ctcccacccc ctcaacaacc acagcattgt ccagaacaag tgagtgggtg
7261 aggagtcaga atgataggtt gagccccttt atgggaggcg cactccagac agctttcatc
7321 acgcccccat cgagtaaggc ttcatcctca tcaggaacag tctcaaccgt tcctagagaa
7381 attttggact cctggactcc tgcatttaac acgcgcaggc agccgctctt cgctcacata
7441 cgtaagcgag gggagtcacg ggcttagtga aaagaatgat ttggtt
//