Typing tool
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Typing tool
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Complete norovirus genomes
| OR546395 | GII.8 | |
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| GII.P8 |
ORF1: 1..5100
ORF2: 5081..6694
ORF3: 6694..7467
LOCUS OR546395 7486 bp RNA linear VRL 09-JAN-2024
DEFINITION Norovirus GII isolate GII/Hu/TH/2020/GII.8[P8]/B7634 nonstructural
polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes, complete cds.
ACCESSION OR546395
VERSION OR546395.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7486)
AUTHORS Chuchaona,W., Vongpunsawad,S., Lawtongkum,W., Thepnarong,N. and
Poovorawan,Y.
TITLE Acute Gastroenteritis Associated with Norovirus GII.8[P8],
Thailand, 2023
JOURNAL Emerg Infect Dis 30 (1), 194-197 (2024)
PUBMED 38147526
REFERENCE 2 (bases 1 to 7486)
AUTHORS Chuchaona,W., Vongpunsawad,S., Lorthongkham,W., Thepnarong,N. and
Poovorawan,Y.
TITLE Direct Submission
JOURNAL Submitted (13-SEP-2023) Department of Pediatrics, Center of
Excellence in Clinical Virology, Chulalongkorn, Phayathai, Bangkok,
Bangkok 10330, Thailand
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7486
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="GII/Hu/TH/2020/GII.8[P8]/B7634"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Thailand"
/collection_date="04-Feb-2020"
/note="genotype: GII.8[P8]"
gene 1..5100
/gene="ORF1"
CDS 1..5100
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="WMY97769.1"
/translation="MKMASNDATAAAGNFNIANNSESTPPPIKEEASVLSNVKVGFKK
ILGAVPKQPKPPEVKTKDQPRVLVNGKALEVPPPPPNGEDVVYYNSKDDTVHGLPNLT
TVSCEGENLPYTVPPLSEREHRAAPEPLPGTILEMWDGEFYHYAIYVSGGKAIGVHKP
PAAISLATIELTPISLYWRPVYVPNYLVHPDTLKSLAGEKFPYTAFSNNCYNFCCWVL
DLKDSWLNRRSITRTTGFFKPYQTWNKKPLPTVDDGKIKKVANAVLCALGSLFSKPIK
DLIGKLKPLNFLNLLASCDWTFSGVVETVILAAELFGVFWTPPDVSNFIASLIGDFEL
QGPEDLAVELVPIIMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVM
KWFFPKKEEKAEMETLRAIEDAVLDMEAIGNNHLTALLKDRDSLLTYMKTLDLEEEKA
RKLSTKSSSPDIVGTINAILARIAAARSLLHRAKEEMYSRPRPVVVMISGRPGVGKTH
MARHLAKSVAGTMSGDQRVGLIPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALALQE
LADTCPVTLNCDRIENKGKMFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEA
PTIEKAKKDFPGQPDMWKEHFKADFSHLKLTLAPQGGFDKNGNTPHGKGTMKTLTQGS
LTARVAGLVHERKDEFQLQGGELQVYNFDTNKVSAFRKLAADNNYGFLETMRVGTSLK
DVKTVEDLKCALKSVSFKECEIIYRNVKYRISSDGCGKVSIEKLADNNSQTTREIITA
VTRLRQARARYYISCFQDLVYTLLQVAGASFVINRIVKKFNWERWVKTPETDEPTPSN
DKPDTEEEWEIAPKDVDSEGKKGKNKKGRGRKHTAFSSKGLSDEEYDEFKRLREEKQG
RYTIEEYLQDRDRYYEELAVARATEENFCEEEEIKIRQRIFRPTKKQRKEERGVLGLV
TGADIRKRRPDDFQPKGKLWADDSRSVDYNEKIEFEAPPSVWSRIVPLGTGWGFWVSS
NLLITTTHVLPKGIKELFGVDIKQVQVHKSGEFCRFRFPKPVRPDVSGLILEEGAPEG
TVCSVLIKRSTGEMIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGD
CGCPYIYKRGNDIVVAGVHTAAARGGNTVICATQGPDGEAVLEGGEDHGTYCGAPILA
PGKAPKLSTKTKFWRSSPDSLPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEEAKKTVMNVLEQTIEPAKPWTYSQACASLDKTTSSGSPHHVRKNEHW
NGESFTGPLADQASKANLMYEEGKHMDPMYTAALKDELVKTDKIYKKIKKRLLWGSDL
GTMVRCARAFGGLLDSMKESCISLPCRVGMNINEDGPLIFEKHSKYTYHYDADYSRWD
STQQRAVLSAAMEVMVKFSAEPELAQVVAEDLLAPSRLDVGDFVISVQEGLPSGVPCT
SQWNSIAHWILTLSAMSEVSGLSPEVVQANSCFSFYGDDEIVSTDINLDPEKLTRKLR
EYGLVPTRPDKTEGPLVITQDLNGLTFLRRTIVRDPAGWFGKLDRDSILRQLYWTRGP
NHENPFESMIPHSQRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQE
AMFRWMRFSDLSTWEGDRNLAPENVNEDGVE"
mat_peptide 1..1005
/gene="ORF1"
/product="p48"
mat_peptide 1006..2103
/gene="ORF1"
/product="NTPase"
mat_peptide 2104..2625
/gene="ORF1"
/product="p22"
mat_peptide 2626..3024
/gene="ORF1"
/product="VPg"
mat_peptide 3025..3567
/gene="ORF1"
/product="Pro"
mat_peptide 3568..5097
/gene="ORF1"
/product="RdRp"
gene 5081..6694
/gene="ORF2"
CDS 5081..6694
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="WMY97770.1"
/translation="MKMASNDAAPSNDGAAGLVPEINHEVMAIEPVAGASLAAPVVGQ
LNIIDPWIRNNFVQAPAGEFTVSPRNAPGEFLLDLELGPELNPYLAHLARMYNGHAGG
MEVQIVLAGNAFTAGKILFAVIPPGFPYENLSPAQLTMCPHVVVDVRQLEPILLPMPD
IRNTFFHYNQSNGPKLRLVAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFEFNFLVPP
SVESKTKAFTLPILKISEMTNSRFPIPVDQMYTSRNENIVVQPQNGRVTLDGELQGTT
TLQPVSICGFRGTLQTRLADQPNYTYQVHLENLDGSPVDPTDEVPAPLGTPDFQAQLF
GVVSQRSSDNATRAHEARVNTNDPTFAPQIAQVRFKSPSHDFFDNEPIKFTPVGISVD
SENSYNQWLLPRYGGHLTNNTHLAPSVSPMFPGEQILFFRSFMPGASGHTDGAIDCLL
PQEWVAHFYQEAATAQTDVALIRFVNPDTGRVLFEGKLHKQGFITISNSGDHPIVMPA
NGYFRFEAWVNQFYSLAPVGTGSGRRRIQ"
gene 6694..7467
/gene="ORF3"
CDS 6694..7467
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="WMY97771.1"
/translation="MAGAFLAGLAGDVVTSGIGSLINAGANAVNQKVEYDFNRQLQEA
SFKHDKEMLNAQINATTKLQRDMIAIKQGVLTAGGFSPTDAARGSINAPTTKILDWNG
SRYWAPGSMRTTAYSGNFISQGVKQPTPIVKSVKPQVQQSPAPSSVYSVGSVKSQSTQ
STQLTGSGTVSRAPTPSTTTTLSRTSEWVRSQNDRLSPFMGGALQTAFITPPSSKASS
SSGTVSTVPREILDSWTPAFNTRRQPLFAHMRRRGESRA"
ORIGIN
1 atgaagatgg cgtctaacga cgctaccgct gccgctggca actttaacat tgccaacaac
61 agtgaaagca ctccccctcc cattaaggaa gaggcgagtg tcctatccaa cgtaaaagtt
121 ggattcaaga aaatattggg ggctgtgcct aagcagccca agccaccaga agtgaaaacc
181 aaagatcaac ccagggtgct ggtcaatggt aaggccctgg aggtgccgcc cccaccacca
241 aatggtgaag acgtggttta ctataacagc aaggatgaca ctgtgcacgg cctaccaaat
301 ctaacaacag tcagctgtga aggtgaaaac cttccgtaca cagttcctcc tctcagcgag
361 agagagcaca gggcagcacc agaaccatta cctggcacca tactagagat gtgggatggt
421 gaattctacc attatgcgat atatgtctct ggtggtaagg ccataggggt gcacaaaccc
481 ccagctgcaa tcagccttgc taccatcgag cttacaccca tatcgcttta ctggaggcct
541 gtctatgtcc ccaattactt ggtccaccct gacacactca agagcttagc tggtgaaaaa
601 tttccataca ccgcatttag caacaattgt tacaatttct gttgctgggt tcttgacttg
661 aaagactcgt ggcttaaccg caggtcaata actagaacaa ccggtttctt caagccttat
721 caaacctgga acaagaaacc actcccgacg gtggatgatg gaaaaatcaa gaaagtcgcc
781 aatgcagtcc tgtgtgccct tggttcacta ttctcaaaac ctattaagga cttgatcggg
841 aagctgaaac cattgaattt cttgaatctc ctcgcttcgt gcgattggac tttctccgga
901 gtggttgaga ccgtcatact agctgctgaa ctattcggag tgttttggac ccctcccgac
961 gtgtcgaact tcatcgcgtc actcatcggg gactttgagt tgcagggtcc agaggattta
1021 gctgtggagt tggtgccgat tatcatgggc ggcatcggga tggtgctggg attcaccgcc
1081 gagaagatcg gccgaatgct atcatcagct gcgtcgaccc ttagggcctg taaagaccta
1141 ggtaactatg cccttgacat acttaaattg gtcatgaagt ggttcttccc aaagaaggag
1201 gaaaaggcag agatggagac cttgagggcc atagaggatg ctgttttgga catggaggcg
1261 attggaaata atcacctcac tgctctgttg aaagacaggg acagtctcct aacctacatg
1321 aagactctag acctcgaaga ggaaaaggca agaaagttat ccacaaaatc atcttcccct
1381 gacatcgtgg gtaccatcaa tgccatacta gccagaattg ccgcggctag gtctctccta
1441 cacagagcta aagaagaaat gtacagcaga cctaggcctg tcgtggtgat gatatcagga
1501 agaccagggg ttggcaaaac ccatatggct agacacctcg ccaagagtgt ggcgggcacc
1561 atgagcggtg accaaagggt gggcctcatc ccccgtaatg gagttgatca ctgggatgcc
1621 tacagggggg aacgagtagt cttgtgggac gactatggca tgggcaaccc agtgaaggac
1681 gcccttgctc tgcaagaact agcagacact tgtccagtca ccctcaattg tgacaggata
1741 gagaataagg gaaagatgtt tgatagcgag gtaataatta taacaaccaa tctggccaac
1801 cccgccccgc ttgattatgt caactttgag gcatgttccc gcagaattga cttcctcgtc
1861 tacgcagagg ccccgaccat tgagaaggcg aagaaggatt tccccggaca accagacatg
1921 tggaaggagc acttcaaagc agacttctct catctcaaac tcacactggc cccacaaggc
1981 ggttttgaca agaacggcaa cacgccacat gggaagggga ctatgaagac cttaacacag
2041 ggttccctca cagcaagagt ggctgggctt gtgcacgaaa ggaaagacga gttccagtta
2101 cagggtggag agttgcaggt ctacaacttt gacacaaaca aggtatcggc tttcaggaag
2161 cttgctgcag acaacaacta tgggtttctg gagacaatga gagtcggcac ctcactcaag
2221 gacgtcaaga cagtggaaga ccttaaatgt gcactcaaga gtgtcagttt caaagaatgt
2281 gaaataatct acaggaatgt caagtaccgc atatcatcag acggttgcgg taaggtcagc
2341 atagagaaac tggcagataa caactcccaa acaaccagag agattatcac ggccgtcact
2401 agactacgac aggctcgtgc taggtactac attagctgct tccaagacct agtctacaca
2461 ctcttgcagg ttgccggagc ctcatttgtc attaatagaa tagttaagaa gttcaactgg
2521 gaacgatggg tcaagacccc agaaacggat gaacccacac caagtaatga caagcccgac
2581 actgaagagg aatgggagat cgcccccaaa gatgtggact ctgagggtaa aaaggggaag
2641 aacaagaagg gcagaggacg taagcacact gcattctcca gcaaagggct tagtgatgag
2701 gagtatgatg aattcaaaag gctgagggaa gagaaacagg gccgctacac aatagaggag
2761 tacctccagg acagagaccg gtactatgaa gagctggcag tggcccgggc cactgaagag
2821 aacttctgtg aagaggaaga gataaagatc aggcaaagaa tattccgccc caccaaaaag
2881 cagaggaagg aggagagggg ggttctggga ctcgtcacag gagcagacat caggaaacgg
2941 agacccgatg atttccaacc aaaaggaaaa ctgtgggcag atgattctag gagcgtcgac
3001 tacaatgaga agatcgagtt tgaagctcct cctagcgtct ggtcaagaat cgtcccgctt
3061 gggactggtt ggggattctg ggtctcatcc aacttactaa tcaccaccac acatgtgctg
3121 cccaaaggca ttaaagagct ttttggggtg gacatcaaac aagtccaagt tcacaaatca
3181 ggtgaatttt gcagattcag gttcccaaaa ccagtgaggc cagatgtctc tgggttgata
3241 ctagaagaag gggcccccga aggcacagtg tgctctgttc tcatcaagag gtcaacagga
3301 gagatgatcc cccttgcagt caggatgggc acccacgcct ctatgaagat ccaggggcgc
3361 actgttggcg gccagatggg catgctgctc actggagcca acgctaagaa catggattta
3421 ggcaccggcc ccggggattg tggttgcccg tacatataca agaggggcaa tgacatcgtg
3481 gtggccggcg tccacacagc agcagcgcgc gggggcaaca cggtcatctg cgcaacccaa
3541 ggacctgatg gtgaggcagt gttggaaggg ggagaggacc acggcactta ttgtggagct
3601 ccaatattgg cccctggtaa agcgccgaag cttagcacaa agactaagtt ttggcgctca
3661 tcccctgatt cccttccccc tgggacgtat gaaccagctt accttggggg taaggatccc
3721 cgtgtggaga aagggccgtc actccaacaa gtgatgcgag accaactcaa acccttcaca
3781 gaacccaggg gcaagccacc taggccgtca gtgctggagg aagccaagaa gacagtcatg
3841 aatgtactgg agcagaccat agaaccagct aagccatgga cctactctca agcctgtgct
3901 tcattggata aaacaacatc cagtggcagt cctcaccacg tcaggaagaa tgaacactgg
3961 aacggggagt ctttcactgg gcctcttgca gatcaagcct caaaagccaa cctgatgtat
4021 gaggagggta aacacatgga ccctatgtac acagcagccc tcaaggacga gttggtgaaa
4081 actgacaaaa tctataagaa aatcaagaag aggttgttgt gggggtctga tctggggaca
4141 atggtaaggt gtgctcgagc gtttggagga ttgctcgaca gcatgaaaga gagttgcatc
4201 tccttaccct gtagggttgg catgaacata aacgaagatg gaccactcat atttgaaaaa
4261 cattccaaat acacctatca ctatgatgct gactactcta ggtgggactc aacacaacag
4321 agggctgtcc tgagtgcagc catggaggta atggtgaagt tctctgctga gccggaactg
4381 gctcaggtgg ttgccgaaga cctccttgca cccagccgtc ttgacgtggg tgacttcgtc
4441 atctccgtcc aagaaggtct tccatcgggt gtcccctgca cgtcacagtg gaactcaatc
4501 gcccactgga tcctgactct tagtgctatg tctgaggtct ctggtctttc ccctgaggtt
4561 gtgcaagcca actcctgttt ctcattctat ggggatgatg aaatagtcag cacagatata
4621 aacctagacc cagaaaaact caccaggaaa ctgagggagt atggcctcgt cccaacaagg
4681 ccagacaaaa ctgagggccc acttgtgatc actcaggatt tgaatggtct cacattcttg
4741 aggcgaacca tagtgcggga ccccgcaggt tggtttggaa aattggatcg tgattccatt
4801 ctaaggcagt tatactggac cagaggaccc aatcatgaga acccctttga aagtatgatt
4861 ccccactccc agagagcaac ccagttaatg gcccttcttg gggaagcctc gttgcatggt
4921 ccccaatttt acaagaaggt gagtaaaatg gtcatcaatg agatcaagag tggtggtctg
4981 gagttttacg tgcccagaca ggaggccatg tttagatgga tgagattttc agacctcagc
5041 acgtgggagg gcgatcgcaa tctggctccc gagaatgtga atgaagatgg cgtcgaatga
5101 cgcagctcca tcgaatgatg gcgcggctgg cctcgtacca gagatcaacc atgaggtcat
5161 ggccatagag cctgttgcag gggcctctct agcagcccct gtcgtaggac aacttaatat
5221 aattgatccc tggattagaa ataattttgt acaagcccct gctggagaat tcactgtttc
5281 gcctagaaat gctccaggtg aatttttgtt agatttagag ttaggtccag aattgaatcc
5341 ttatcttgct caccttgcac gcatgtataa tgggcatgca ggtggtatgg aggtgcagat
5401 agtgcttgct gggaatgcgt tcacagcggg caaaatactg tttgcagtca taccacctgg
5461 attcccctat gaaaatttgt cacctgcaca attgaccatg tgcccacatg tagtggtgga
5521 tgtgaggcag cttgaaccaa tcttgctgcc catgccagac atccgtaata cattcttcca
5581 ttacaatcag agcaatgggc caaaactcag attagtagct atgctttaca cacccctaag
5641 ggctaacaat gctggtgatg atgtcttcac agtctcctgc agggttctga ctcgtccatc
5701 accagatttt gaattcaact ttcttgtccc cccatctgtt gaatctaaga ctaaagcttt
5761 tactcttcca attcttaaga tatctgagat gacaaattca agatttccca taccagttga
5821 ccagatgtat actagtagga atgaaaatat agttgttcaa ccacagaatg gcagggtgac
5881 acttgatgga gagttacagg gcacaaccac actccaaccg gtgtccattt gtggctttcg
5941 ggggacgctg cagaccaggc tggcagatca accaaattac acataccaag tgcaccttga
6001 gaatttggac ggctcacccg tcgatccgac agatgaagtc ccagcccccc tggggacgcc
6061 agattttcag gcccaactgt ttggagttgt cagccaaagg agtagtgata atgccaccag
6121 ggcacatgag gctagggtca acaccaacga tcctaccttc gcgccccaga tcgcccaggt
6181 gcgtttcaaa tcaccatccc acgacttctt tgacaatgaa cccatcaagt tcacaccagt
6241 tggaattagt gttgatagcg aaaacagcta caaccaatgg ctccttccca ggtatggcgg
6301 gcacttgaca aacaacactc acctggcccc ctctgtgtcc ccaatgttcc ccggcgagca
6361 gattctcttc ttccgctcgt tcatgccagg tgccagtggt catactgatg gcgctattga
6421 ctgcctttta ccacaagagt gggttgccca cttctatcag gaggccgcaa ctgcccaaac
6481 agatgtggct ctgattagat ttgtgaaccc cgacacaggc agagtgctat ttgaagggaa
6541 gctacacaag cagggcttta taaccatctc caacagtggg gaccacccca ttgttatgcc
6601 tgctaatgga tacttcaggt ttgaggcatg ggtcaaccaa ttttactctc tcgcccccgt
6661 gggaactgga agtgggcgca gaaggattca ataatggctg gagcttttct tgcgggtctg
6721 gctggtgatg tggtgacctc tggcatcggg tcgctcatca atgcaggtgc taatgcagta
6781 aaccaaaagg ttgaatatga tttcaatagg caacttcaag aagcttcttt taaacatgac
6841 aaggagatgt tgaatgctca aattaatgcc actaccaaat tgcagaggga catgattgcc
6901 atcaagcagg gggttttgac cgctggcggc ttttccccca ctgatgctgc aagaggttcc
6961 atcaatgctc caaccaccaa aattcttgac tggaatggat ctaggtactg ggcgccagga
7021 tcaatgagaa caacagcata ctctggcaat ttcatatcac agggagttaa gcagcctaca
7081 cccattgtta aatctgtgaa accccaagta cagcaatctc ctgccccttc ttctgtttat
7141 tctgtaggtt ctgttaagtc acaatcaaca caatcaactc aattaacagg gtcagggact
7201 gtgtcaaggg cacccacccc ctcaacaacc acaacactgt ccagaacaag tgagtgggtg
7261 aggagccaga atgataggct gagccccttt atgggaggcg cactccagac agctttcatc
7321 acgcccccat cgagtaaggc ttcatcctca tcaggaacag tctcaaccgt tcctagagaa
7381 attttggact cctggactcc tgcatttaac acacgcaggc agccgctctt cgcccacatg
7441 cgtaggcgag gggagtcacg ggcttagtga aaagaatgat ttggtt
//