Typing tool
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Typing tool
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Complete norovirus genomes
| OR546393 | GII.8 | |
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|---|---|---|---|
| GII.P8 |
ORF1: 1..5100
ORF2: 5081..6694
ORF3: 6694..7467
LOCUS OR546393 7486 bp RNA linear VRL 09-JAN-2024
DEFINITION Norovirus GII isolate GII/Hu/TH/2018/GII.8[P8]/B6213 nonstructural
polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes, complete cds.
ACCESSION OR546393
VERSION OR546393.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7486)
AUTHORS Chuchaona,W., Vongpunsawad,S., Lawtongkum,W., Thepnarong,N. and
Poovorawan,Y.
TITLE Acute Gastroenteritis Associated with Norovirus GII.8[P8],
Thailand, 2023
JOURNAL Emerg Infect Dis 30 (1), 194-197 (2024)
PUBMED 38147526
REFERENCE 2 (bases 1 to 7486)
AUTHORS Chuchaona,W., Vongpunsawad,S., Lorthongkham,W., Thepnarong,N. and
Poovorawan,Y.
TITLE Direct Submission
JOURNAL Submitted (13-SEP-2023) Department of Pediatrics, Center of
Excellence in Clinical Virology, Chulalongkorn, Phayathai, Bangkok,
Bangkok 10330, Thailand
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7486
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="GII/Hu/TH/2018/GII.8[P8]/B6213"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Thailand"
/collection_date="18-Sep-2018"
/note="genotype: GII.8[P8]"
gene 1..5100
/gene="ORF1"
CDS 1..5100
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="WMY97763.1"
/translation="MKMASNDATAAAGNFNIANNSENTPPPIKEEASVLSNVKVGFKK
ILGAVPKQPKPPEVKTKDQPRVLVNGKALEVPPPPPNGEDVVYYNSKDDTVHGLPNLT
TVSCEGENLPYTVPPLSEREHRAAPEPLPGTILEMWDGEFYHYAIYVSGGKAIGVHKP
PAAISLATIELTPISLYWRPVYVPNYLVHPDTLKSLAGEKFPYTAFSNNCYNFCCWVL
DLKDSWLNRRSITRTTGFFKPYQSWNKKPLPTVDDGKIKKVANAVLCALGSLFSKPIK
DLIGKLKPLNFLNLLASCDWTFSGVVETVILVAELFGVFWTPPDVSNFIASLVGDFEL
QGPEDLAVELVPIIMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVM
KWFFPKKEEKAEMETLRAIEDAVLDMEAIGNNHLTALLKDRDSLLTYMKTLDLEEEKA
RKLSTKSSSPDIVGTINAILARIAAARSLLHRAKEEMYSRPRPVVVMISGRPGVGKTH
MARHLAKSVAGTMSGDQRVGLIPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALALQE
LADTCPVTLNCDRIENKGKMFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEA
PTIEKAKKDFPGQPDMWKEHFKADFSHLKLTLAPQGGFDKNGNTPHGKGTMKTLTQGS
LTARVAGLVHERKDEFQLQGGELQVYNFDTNKVSAFRKLAADNNYGFLETMRVGSSLK
DVKTVEDLKCALKSVSFKECEIIYRNVKYRISSDGCGKVSIEKLADNNSQTTREIITA
VTRLRQARARYYISCFQDLVYTLLQVAGASFVINRIVKKFNWERWVKAPETDEPTPSN
GKPDTEEEWEIAPKDVDSEGKKGKNKKGRGRKHTAFSSKGLSDEEYDEFKRLREEKQG
RYTIEEYLQDRDRYYEELAVARATEENFCEEEEIKIRQRIFRPTKKQRKEERGVLGLV
TGADIRKRKPDDFQPKGRLWADDSRSVDYNEKIEFEAPPSVWSRIVPLGTGWGFWVSS
NLLITTTHVLPKGIKELFGVDIKQVQVHKSGEFCRFRFPKPVRPDVSGLVLEEGAPEG
TVCSVLIKRSTGEMIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGD
CGCPYIYKRGNDIVVAGVHTAAARGGNTVICATQGPDGEAVLEGGEDHGTYCGAPILA
PGKAPKLSTKTKFWRSSPDSLPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEP
RGRPPRPSVLEEAKKTVMNVLEQTIEPAKPWTYSQACASLDKTTSSGSPHHVRKNEHW
NGESFTGPLADQASKANLMYEEGKHMDPMYTAALKDELVKTDKIYKKIKKRLLWGSDL
GTMVRCARAFGGLLDSMKESCISLPCRVGMNINEDGPLIFEKHSKYTYHYDADYSRWD
STQQRAVLSAAMEVMVKFSAEPELAQVVAEDLLAPSRLDVGDFVISVQEGLPSGVPCT
SQWNSIAHWILTLSAMSEVSGLSPEVVQANSCFSFYGDDEIVSTDINLDPEKLTRKLR
EYGLVPTRPDKTEGPLVITQDLNGLTFLRRTIVRDPAGWFGKLDRDSILRQLYWTRGP
NHENPFESMIPHSQRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQE
AMFRWMRFSDLSTWEGDRNLAPENVNEDGVE"
mat_peptide 1..1005
/gene="ORF1"
/product="p48"
mat_peptide 1006..2103
/gene="ORF1"
/product="NTPase"
mat_peptide 2104..2625
/gene="ORF1"
/product="p22"
mat_peptide 2626..3024
/gene="ORF1"
/product="VPg"
mat_peptide 3025..3567
/gene="ORF1"
/product="Pro"
mat_peptide 3568..5097
/gene="ORF1"
/product="RdRp"
gene 5081..6694
/gene="ORF2"
CDS 5081..6694
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="WMY97764.1"
/translation="MKMASNDAAPSNDGAAGLVPEINHEVMAIEPVAGASLAAPVVGQ
LNIIDPWIRNNFVQAPAGEFTVSPRNAPGEFLLDLELGPELNPYLAHLARMYNGHAGG
MEVQIVLAGNAFTAGKILFAVIPPGFPYENLSPAQLTMCPHVVVDVRQLEPILLPMPD
IRNTFFHYNQSNGPKLRLVAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFEFNFLVPP
SVESKTKAFTLPILKISEMTNSRFPIPVDQMYTSRNENIVVQPQNGRVTLDGELQGTT
TLQPVSICGFRGTLQTRLADQPNYTYQAHLENLDGSPVDPTDEVPAPLGTPDFQAQLF
GVVSQRSSDNATRAHEARVNTNDPTFAPQIAQVRFKSPSHDFFDNEPIKFTPVGISVD
SENSYNQWLLPRYGGHLTNNTHLAPSVSPMFPGEQILFFRSFMPGASGHTDGAIDCLL
PQEWVAHFYQEAATAQTDVALIRFVNPDTGRVLFEGKLHKQGFITISNSGDHPIVMPA
NGYFRFEAWVNQFYSLAPVGTGSGRRRVQ"
gene 6694..7467
/gene="ORF3"
CDS 6694..7467
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="WMY97765.1"
/translation="MAGAFLAGLAGDVVTSGIGSLINAGANAVNQKIEYDFNRQLQEA
SFKHDKEMLNAQINATTKLQRDMIAIKQGVLTAGGFSPTDAARGSINAPTTKILDWNG
SRYWAPGSMRTTAYSGNFISQGVKQPTPIVRSVKPQVQQPPAPSSVYSVGSVRSQSTQ
STQLTGSGTVSRAPTPSTTTTLSRTSEWVRSQNDRLSPFMGGALQTAFITPPSSKASS
SSGTVSTVPREILDSWTPAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 atgaagatgg cgtctaacga cgctaccgct gccgctggca actttaacat tgccaacaac
61 agtgaaaaca ctccccctcc cattaaggaa gaggcgagtg tcctatccaa cgtaaaagtt
121 ggattcaaga aaatattggg ggctgtgccc aagcagccca agccaccaga agtgaaaacc
181 aaagatcagc ccagggtgct ggtcaatggt aaggccttgg aggtgccgcc cccaccacca
241 aatggtgaag acgtggttta ctataacagc aaggatgaca ccgtgcatgg tctaccaaat
301 ttaacaacag tcagctgtga aggtgaaaac ctcccgtaca cagtcccccc tctcagcgag
361 agagagcaca gggcagcacc agaaccatta cctggtacca tactagagat gtgggatggt
421 gagttctacc attatgcgat atatgtctct ggtggcaagg ccataggggt gcacaaaccc
481 ccagccgcaa tcagccttgc cactatcgag cttacaccta tatcgcttta ctggaggccc
541 gtttatgtcc ctaattactt ggtccaccct gacacactca agagcttagc tggtgaaaaa
601 tttccataca ccgcatttag caacaattgt tacaatttct gctgctgggt tcttgacctg
661 aaagactcgt ggctcaaccg cagatcaata actagaacaa ccggtttctt caagccctat
721 caatcctgga ataagaaacc acttccgacg gtggatgatg gaaaaatcaa gaaagtcgcc
781 aatgcagtcc tgtgtgccct tggttcacta ttctcaaaac ctattaagga cttgatcggg
841 aagctgaaac cactgaattt cttgaatctc ctcgcctcgt gcgactggac cttctctgga
901 gtggttgaaa ccgttatact agttgctgag ctgtttggtg tgttttggac cccccccgac
961 gtgtcgaatt tcatcgcgtc actcgtcggg gactttgagc tgcagggtcc agaggattta
1021 gctgtggagt tggtgccgat catcatgggc ggtatcggga tggtgctggg attcaccgcc
1081 gagaagatcg gccgaatgct atcatcggct gcatcgaccc ttagggcctg taaagaccta
1141 ggcaactacg cccttgacat acttaaattg gtcatgaagt ggttcttccc aaagaaggag
1201 gaaaaggcag agatggaaac cttgagggct atagaggatg ctgtcttaga catggaggcg
1261 attggaaata atcacctcac tgctctgttg aaagacaggg acagcctcct aacttacatg
1321 aagactctag accttgaaga agaaaaggca agaaagctgt ccacaaaatc atcgtcccct
1381 gacatcgtgg gtaccatcaa tgccatacta gccagaattg ccgcggctag gtctctcctg
1441 cacagagcca aggaagaaat gtacagcaga cctaggcctg tcgtggtgat gatatcagga
1501 agaccagggg ttggtaagac ccatatggct agacacctcg ccaagagtgt ggcgggcacc
1561 atgagtggtg accaaagggt gggcctcatc ccccgcaatg gagttgatca ttgggatgcc
1621 tacaggggag aacgagttgt cttgtgggac gactatggca tgggtaaccc agtgaaggat
1681 gccctcgctc tgcaagaact agcagacact tgtccagtca ccctcaattg tgacaggata
1741 gagaataagg ggaagatgtt tgatagcgag gtaataatta taacaactaa tttggccaac
1801 cccgccccgc ttgattatgt caactttgaa gcttgttccc gcagaatcga cttcctcgtc
1861 tacgcagaag ccccgaccat tgagaaggcg aagaaggatt ttcccgggca accagatatg
1921 tggaaggagc acttcaaagc agacttctct catctcaaac tcacactggc cccgcaaggc
1981 ggttttgaca agaacggcaa cacgccacat gggaagggga ctatgaagac cttaacacag
2041 ggttccctca cagcaagagt ggctggactt gtgcacgaaa gaaaagatga gtttcagtta
2101 cagggtggag agttgcaggt ctacaatttt gacacaaaca aggtatcggc tttcaggaag
2161 cttgctgcag acaacaacta tgggttcctg gagacaatga gagtcggctc ctcactcaag
2221 gatgtcaaga cagtggaaga tcttaaatgt gcccttaaga gtgtcagttt caaagaatgt
2281 gaaataatct ataggaatgt taagtaccgc atatcatcag acggttgcgg taaggtcagc
2341 atagagaaac tggcagataa caactcccaa acaaccagag agattatcac ggccgtcact
2401 agactacgac aggctcgtgc tagatattac atcagctgct tccaagacct agtctacaca
2461 ctcttgcagg ttgccggagc ctcatttgtc attaacagaa tagtcaagaa gttcaactgg
2521 gaacgatggg tcaaggctcc agaaacagat gaacccacac caagtaatgg caagcccgac
2581 actgaagagg aatgggagat cgcccccaaa gatgtagact ctgagggcaa aaaggggaag
2641 aacaagaagg gcaggggacg taagcacact gcattctcca gcaaagggct tagtgatgag
2701 gagtatgatg aattcaaaag actaagggaa gagaaacagg gccgctacac aatagaggag
2761 tacctccagg acagggaccg gtactatgaa gagctggcag tggcccgggc cactgaggag
2821 aacttctgtg aagaggaaga gataaagatc aggcaaagga tattccgccc caccaaaaag
2881 cagaggaagg aggagcgcgg ggttctggga ctcgtcacag gagcagacat caggaaacgg
2941 aaacccgatg acttccaacc aaaaggaaga ttgtgggcag atgattctag gagcgtcgat
3001 tacaatgaga agatcgagtt tgaagctcct cctagcgtct ggtcaagaat tgtcccgctt
3061 gggactggtt ggggattctg ggtctcatcc aacttactaa ttaccaccac acatgtgctg
3121 cccaaaggta ttaaagagct ttttggggtg gacatcaaac aagtccaagt ccacaaatca
3181 ggtgaatttt gcagattcag gttcccaaaa ccagtgaggc cagatgtctc tgggttggtg
3241 ttagaagaag gggcccccga aggcacagtg tgctctgttc tcatcaagag gtctacagga
3301 gagatgatcc cccttgcagt taggatgggc acccacgcct ctatgaagat tcaggggcgc
3361 actgttggcg gccagatggg catgctgctc actggagcca acgctaagaa catggatttg
3421 ggtaccggcc ccggggattg tggttgcccg tatatataca agaggggcaa tgacatcgtg
3481 gtggccggcg tccacacagc agcggcgcgc gggggcaaca cggtcatctg tgcaacccaa
3541 ggacctgatg gtgaggcagt gttggaaggg ggagaggacc acggtactta ctgtggagcc
3601 ccaatactgg cccctggtaa agcgccgaag cttagcacaa agaccaagtt ttggcgctca
3661 tcccctgatt cccttccccc tgggacgtat gaaccagctt accttggggg caaggacccc
3721 cgtgtggaga aagggccgtc actccaacaa gtgatgcgag accaactcaa acccttcaca
3781 gaacccaggg gcaggccacc taggccgtca gtgctggagg aagccaagaa gacagtcatg
3841 aatgtactgg agcagaccat agaaccagct aagccatgga cctactctca agcctgtgct
3901 tcattggata aaacaacatc cagtggcagc cctcaccatg tcaggaagaa tgaacactgg
3961 aacggggagt cttttactgg gcctcttgca gatcaagcct caaaagccaa cctgatgtat
4021 gaggaaggta aacatatgga ccctatgtat acagcagccc tcaaggacga gctggtaaaa
4081 actgacaaaa tctataagaa aatcaagaag aggttgttgt gggggtctga tctggggaca
4141 atggtgaggt gtgctcgagc gtttggagga ttgctcgaca gtatgaaaga gagttgcatt
4201 tccttacctt gtagggttgg catgaacata aatgaagatg gaccactcat atttgaaaaa
4261 cattccaaat acacctatca ctatgatgct gattactcta ggtgggactc aacacaacag
4321 agggctgtac tgagtgcagc tatggaggta atggtgaagt tctccgctga gccggaactg
4381 gctcaggtgg ttgccgaaga cctccttgca cccagccgtc ttgacgtggg tgactttgtc
4441 atctccgttc aagaaggtct cccatcgggt gtcccctgca cgtcacagtg gaactcaatt
4501 gctcattgga ttctgactct tagtgctatg tctgaggttt ctggtctttc ccctgaggtt
4561 gtgcaagcca actcctgttt ctcattctat ggggatgatg agatagttag tacagatata
4621 aatctggacc cagaaaaact caccaggaaa ctgagggaat atggcctcgt cccaacaagg
4681 ccagacaaaa ctgagggccc acttgtgatt actcaggatt tgaatggtct cacatttctg
4741 agacgaacca tagtgcggga ccccgcaggc tggtttggaa aactggaccg tgattccatt
4801 ctgaggcaat tatactggac cagaggaccc aatcatgaga acccctttga aagcatgatt
4861 ccccactccc agagagcaac ccagctaatg gcccttcttg gggaagcctc gttgcatggt
4921 ccccagtttt acaagaaggt gagtaaaatg gtcatcaatg agatcaagag tggtggtctg
4981 gagttttacg tgcccagaca ggaggccatg tttagatgga tgagattttc agacctcagc
5041 acgtgggagg gcgatcgcaa tctggctccc gagaatgtga atgaagatgg cgtcgaatga
5101 cgcagctcca tcgaatgatg gcgcggctgg cctcgtacca gagatcaacc atgaggtcat
5161 ggccatagag cctgttgcag gagcctcctt agcagctcct gtcgtaggac aacttaatat
5221 aattgatccc tggattagaa ataattttgt acaggcccct gctggagaat tcactgtttc
5281 gcccaggaat gctccaggtg aatttttatt agatctagag ttaggtccag aattgaatcc
5341 ttatcttgct caccttgcac gcatgtacaa tgggcatgca ggtggtatgg aggtgcagat
5401 agtgcttgct gggaatgcgt tcacagcagg caaaatactg tttgcagtca taccgcctgg
5461 attcccctat gaaaatttgt cacctgcaca attgaccatg tgcccacatg tagtggtgga
5521 tgtgaggcag cttgaaccaa tcttgctgcc catgccagac atccgcaaca cattcttcca
5581 ttacaaccag agcaatgggc caaaacttag attagtagct atgctttata cacccctaag
5641 ggctaacaat gctggtgatg atgtcttcac agtttcctgc agggttttga cccgcccatc
5701 accagatttt gaattcaatt ttcttgtccc cccatctgtt gaatctaaga ctaaagcttt
5761 cacccttcca attcttaaga tatctgagat gacaaattca agatttccca taccagttga
5821 ccagatgtat actagtagga atgaaaatat agttgttcaa ccacaaaatg gcagggtgac
5881 acttgatgga gagctacagg gcacaaccac actccaaccg gtgtccattt gtggcttccg
5941 agggacgctg cagaccaggc tggcagatca accaaattac acataccaag cgcaccttga
6001 gaatttggac ggctcacccg tcgacccgac agatgaagtt ccagcccccc tggggacacc
6061 agattttcag gctcagctat ttggagttgt cagccaaagg agtagtgata acgccaccag
6121 ggcacatgag gccagggtca acaccaacga tcctaccttc gcgccccaga tcgcccaggt
6181 gcgtttcaaa tcaccatctc acgacttctt tgacaatgaa cccatcaaat tcacaccagt
6241 cggaatcagt gttgatagcg aaaacagcta caaccaatgg ctcctaccca ggtatggtgg
6301 acacctgaca aacaacaccc acctggcccc ctctgtgtcc ccaatgttcc ccggcgagca
6361 gattctcttc ttccgctcgt tcatgccagg tgccagtggt cacactgatg gtgctattga
6421 ctgcctttta ccacaagagt gggttgccca cttctatcag gaggccgcaa ctgcgcaaac
6481 agatgtggct ctgattagat ttgtgaaccc cgacacaggc agagtgctat ttgaagggaa
6541 gttacacaag cagggtttta taaccatctc caacagcggg gaccacccca ttgttatgcc
6601 tgctaatgga tacttcaggt ttgaggcatg ggtcaaccaa ttttactctc tcgcccccgt
6661 gggaactgga agtgggcgca gaagagttca ataatggctg gagcttttct tgctggtctg
6721 gctggtgatg tggtgacctc tggcatcggg tcgctcatca atgcaggtgc caatgcagtg
6781 aaccaaaaga ttgaatatga cttcaatagg caactccaag aagcttcttt taaacatgac
6841 aaggagatgt tgaatgctca aattaatgcc acaaccaaat tgcaaaggga catgattgcc
6901 attaagcagg gggttttgac cgctggcggc ttttccccca ctgatgctgc aaggggttcc
6961 atcaacgctc caaccaccaa aattcttgac tggaacggat ctaggtactg ggcaccagga
7021 tcaatgagaa caacagcgta ctctggcaat tttatatcac agggagttaa gcagcccaca
7081 cccattgtta ggtctgtgaa acctcaagta cagcaacctc ctgccccttc ttctgtttat
7141 tctgtaggtt ctgttaggtc acaatcaaca caatcaaccc aattaacagg gtcagggact
7201 gtatcaaggg cacccacccc ctcaacaacc acaacactgt ccagaacaag tgagtgggtg
7261 aggagccaga atgataggtt gagccccttt atgggaggcg cactccagac agctttcatc
7321 acgcccccat cgagtaaggc ttcatcctca tcaggaacag tctcaaccgt tcctagagaa
7381 attttggact cctggactcc tgcatttaac acgcgcaggc agccgctctt cgctcacata
7441 cgtaagcgag gggagtcacg ggcttagtga aaagaatgat ttggtt
//