Typing tool
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Typing tool
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Complete norovirus genomes
| OR069405 | GII.6 | |
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| GII.P7 |
ORF1: 1..5094
ORF2: 5075..6718
ORF3: 6718..7494
LOCUS OR069405 7546 bp RNA linear VRL 06-OCT-2023
DEFINITION Norovirus GII isolate GII/Hu/US/2015/GII.6[P7]/NIH53.1
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION OR069405
VERSION OR069405.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7546)
AUTHORS Chaimongkol,N., Dabilla,N., Tohma,K., Matsushima,Y., Behrle
Yardley,A., Levenson,E.A., Johnson,J.A., Ahorrio,C., Oler,A.J.,
Kim,D.Y., Souza,M., Sosnovtsev,S.V., Parra,G.I. and Green,K.Y.
TITLE Norovirus Evolves as One or More Distinct Clonal Populations in
Immunocompromised Hosts
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7546)
AUTHORS Chaimongkol,N., Dabilla,N., Sosnovtsev,S.V. and Green,K.Y.
TITLE Direct Submission
JOURNAL Submitted (26-MAY-2023) LID, NIAID, 50 South Drive/R6318, Bethesda,
MD 20892, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: HIVE Hexagon/Heptagon v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7546
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="GII/Hu/US/2015/GII.6[P7]/NIH53.1"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="Dec-2015"
/note="genotype: GII.6"
gene 1..5094
/gene="ORF1"
CDS 1..5094
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="WID03731.1"
/translation="MKMASNDASAAFGSQNSVNDSINTAPSGKEEVGTFSNIKVGFKK
MLGAVPKGTKAPSGDQHCPSVKIGTKTLTVPPEPPNGEDTVQFDAKSGTVRGLPDLTT
VQNEHENTPYTVPPLSEREHRPATEPLPGTILEMWDGEFYHYSVYVSGGKALGVHKPP
AAISLATIELTPISLYWRPVYTPNYLVCPDTLKGLAGEKFPYTAFSNNCYNFCCWVLE
LNDTWLSRRSISRTTGFFKPYQSWNRKPLPTVDDGKIKKVANAILCALGSLFSKPIKD
LLGKLKPLNLLHLLASCDWTFAGIVETVILMAELFNIFWTPPDVSSFIASLIGDFELQ
GPEDLAVELVPVVMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMK
WFFPKKEEKAGMETLRAIEDAVLDMEAIGNNHLTTLLKDKDSLAAFMKTLDLEEEKAR
KLSTKSSSPDIVGTINAILARIAAARSLLHKAKEEMFSRIRPVVVMISGRPGIGKTHM
ARHLAKSIANTMSGDQRVGLVPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALTLQEL
ADTCPVTLNCDRIENKGKMFDSDVIIITTNLVNPAPLDYVNFEACSRRVDFLVYAESP
EIEKVKRDFPGQPDMWKDHFKPDFSHIKLTLAPQGGFDKNGNTPHGKGTMRSLTQGSL
TARVAGLVYERRDEFQLQGNDLQTYNFDTNRVSAFRKLAADNKYGIMETMRVGTALKS
VKTLEDLKVALRDVKFNECEIIYRNSKYRVSSNGKGSVSVDKVEDQTSQTANEVGAAL
LRLRQARARYYVSCFQDLVYTLIQVAGASFVVNRISKRFCWERWVKPTETQETSESEK
EVAQGRWEIEPKDTEPEGKKGKNKKGRGKKHTAFSSKGLSDEEYDEFKRIREERNGKY
SIEEYLQDRDRYYEEVAVARATEEDFCEEEEAKIRQRIFRPTKKQRKEERGVLGLVTG
SDIRKRRPDDFQPKGNLWADDTRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSNL
LITTTHVLPKGIKELFGVEIKQIQIHKSGEFCRFRFPRPIRPDVTGLVLEEGAPEGTV
CSILVKRPTGEMIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDCG
CPYIYKRGNDIVVAGVHTAAARGGNTVICATQGQDGEAVLEGNENLGTYCGAPILGPG
KAPKLSTKTKFWRSSPDALPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEPRG
KPPRPAVLEEAKRTVMNVLEQTIDPAKPWTYSQACASLDKTTSSGSPHHVRKNDHWNG
ESFTGPLADQASKANLMYEQAKHVQPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGT
MIRCARAFGGLMDSMKASCIALPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDST
QQRNILSAAMEVMVRFSAEPELAQVVAEDLLAPSQLDVGDFVISVQEGLPSGVPCTSQ
WNSIAHWILTLSAMAEVSGLSPDVVQAHSCFSFYGDDEIVSTDINLDPMKLTQKLREY
GLVPTRPDKTEGPLVITEDLTGLTFLRRSIARDPAGWFGKLDQDSILRQLYWTRGPNH
ENPYESMVPHSQRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEAM
FRWMRFSDLSTWEGDRNLAPEGVNEDGVE"
mat_peptide 1..1002
/gene="ORF1"
/product="p48"
mat_peptide 1003..2100
/gene="ORF1"
/product="NTPase"
mat_peptide 2101..2619
/gene="ORF1"
/product="p22"
mat_peptide 2620..3018
/gene="ORF1"
/product="VPg"
mat_peptide 3019..3561
/gene="ORF1"
/product="Pro"
mat_peptide 3562..5091
/gene="ORF1"
/product="RdRp"
gene 5075..6718
/gene="ORF2"
CDS 5075..6718
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="WID03732.1"
/translation="MKMASNDAAPSNDGAANLVPEATNEVMALEPVVGASIAAPVVGQ
QNIIDPWIRENFVQAPQGEFTVSPRNSPGEMLLNLELGPELNPYLSHLSRMYNGYAGG
MQVQVVLAGNAFTAGKIIFAAVPPHFPVENISAAQITMCPHVIVDVRQLEPVLLPLPD
IRNRFFHYNQENTPRMRLVAMLYTPLRANSGEDVFTVSCRVLTRPAPDFEFTFLVPPT
VESKTKPFTLPILTLGELSNSRFPAPIDMLYTDPNEAIVVQPQNGRCTLDGTLQGTTQ
LVPTQICSFRGTLISQTSRSADSTDSAPRVRNHPLHVQLKNLDGTPYDPTDEVPAVLG
AIDFKGTVFGVGSQRNTTGNSIGATRAHEVHIDTTNPRYTPKLGSVLMHSESTDFDDG
QPIRFTPIGMGADDWHQWELPEYSGHLTLNMNLAPAVAPAFPGERVLFFRSVVPSAGG
YGSGHIDCLIPQEWVQHFYQEAAPSQSAVALIRYVNPDTGRNIFEAKLHREGFITVAN
SGNNPIVVPPNGYFRFEAWVNQFYTLTPMGTGQGRRRVQ"
gene 6718..7494
/gene="ORF3"
CDS 6718..7494
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="WID03733.1"
/translation="MAGAFLAGLAGDAITSGVGSLINAGANAINQKVEYDFNKQLQLA
SFKHDKEMLQSQVLATKQLQQEMMNIRQGVLSAGGFSPTDAARGAVNAPMTKILDWNG
TRYFAPNSMKTTSYSGQFSSNPVHRQPTLPRSDPPKIKVNSDSASVYSSASTAPSQST
HSTTLTAGSSSSRTTSSSAVASTLSRTSDWVRGQNERLSPFMDGALQTTFVTPPSSKA
SSYGSVSTVPKAVLDSWTPMFNTHRQPLFAHVRRRGESQI"
ORIGIN
1 atgaagatgg cgtctaacga cgcttccgct gcctttggca gccaaaactc tgtcaatgac
61 agtatcaaca ccgccccttc tggtaaagaa gaggttggta cattttccaa catcaaagtt
121 ggttttaaga aaatgctggg tgccgttccc aaggggacca aagcacccag tggtgatcag
181 cactgcccct cagttaagat cgggaccaag acattaacag ttccccctga gcccccaaat
241 ggtgaagaca ccgtgcagtt tgatgcaaag tcgggaactg tgcgcgggct accagacttg
301 acaacggtgc agaatgaaca cgaaaataca ccatacactg tccccccatt gagtgaaagg
361 gagcacagac cagccactga accgcttcct ggcacaatac tggagatgtg ggatggtgaa
421 ttctaccact actctgtgta cgtcagcggt ggcaaagccc taggggttca caagcccccc
481 gcagcgataa gcctcgcgac gatagagctc acacccatat ctctttattg gaggcccgtt
541 tacaccccca attatctggt ctgtccagac acgttgaaag gccttgctgg tgagaagttc
601 ccttacacgg ccttcagcaa caactgttac aacttctgtt gctgggtgct tgagcttaat
661 gacacgtggc ttagcaggag aagcatctct aggactaccg gcttcttcaa accatatcag
721 tcttggaata ggaaacccct tccaaccgtt gatgatggaa agatcaaaaa ggtggccaac
781 gcaattctct gcgcgcttgg atcactgttt tcaaaaccaa tcaaggacct attgggcaaa
841 cttaaaccat tgaacttact gcacttgctc gcatcgtgtg actggacgtt tgcgggtata
901 gtagagacag tcatcctaat ggcggagctt tttaacatct tttggacacc gccagatgtt
961 tccagtttca tagcctccct gataggtgat tttgaattgc aagggcctga ggacctggct
1021 gtggagcttg tccccgtggt catgggtggc ataggaatgg ttctcggctt tactgctgag
1081 aagataggcc gcatgctgtc gtccgctgca tcaacactac gggcatgcaa agacttgggg
1141 aattatgccc ttgacatatt gaaactggtt atgaagtggt tcttcccaaa gaaagaagag
1201 aaagccggga tggaaaccct gagggcaatt gaggatgccg tcctagacat ggaagctata
1261 ggaaacaatc acctcacaac ccttctcaag gacaaggaca gcctcgcggc tttcatgaag
1321 actctagatc tagaagagga gaaggcaagg aagctgtcca ccaaatcatc ctcgccagac
1381 attgtcggca ctatcaatgc catactggcc agaatagctg ctgccaggtc cctcttgcac
1441 aaggctaaag aagaaatgtt tagcaggatc agacccgtgg ttgtcatgat ctcgggtaga
1501 cctggcattg gcaaaaccca catggcaaga cacttggcta agagcatcgc caacaccatg
1561 agcggcgacc agagagtggg gctcgtccca cgcaacgggg tcgatcattg ggacgcctac
1621 aggggagaga gggtggtctt atgggatgat tatggcatgg gaaaccctgt caaagatgcc
1681 ctaacactgc aagagttggc cgacacctgc ccagtaactc taaactgtga taggatcgag
1741 aataagggga agatgtttga cagtgatgtc atcataatca cgaccaattt agtcaaccca
1801 gcgcccctcg attatgtaaa cttcgaggcg tgctccagaa gggtcgactt tctggtctat
1861 gcagagtcac cagaaattga gaaggttaag agagattttc ccggccaacc tgacatgtgg
1921 aaggaccact ttaagccaga cttttcccac ataaaactga ctctagcccc acagggtgga
1981 tttgataaga atggcaacac cccccatggc aagggcacca tgcgatccct aacccagggg
2041 tccctgactg caagggttgc aggtcttgtt tatgagagga gagacgagtt tcagctccag
2101 gggaacgatc ttcaaacata caactttgac accaacaggg tctctgcatt taggaagctg
2161 gccgcagaca acaagtatgg gatcatggag actatgagag tgggcacagc gcttaagagt
2221 gtcaagacct tggaagatct caaagttgca ctgagggacg tgaagttcaa tgagtgtgag
2281 ataatttaca gaaactccaa ataccgagtc tcctccaatg gtaagggttc tgtctctgtt
2341 gacaaagttg aggaccaaac atcccagact gcaaacgaag tgggtgcagc actccttaga
2401 ctcaggcagg caagagccag atactatgtc agctgcttcc aagatctcgt ttacactcta
2461 atacaggtcg ccggagcatc attcgttgtc aacaggatct ctaaaaggtt ctgctgggag
2521 agatgggtca aaccaaccga gacccaggaa acgagtgaat ccgaaaagga agtggcccaa
2581 ggcagatggg agattgagcc caaggacaca gaaccagaag gtaagaaggg taagaacaag
2641 aaaggaagag gcaagaaaca cacagctttc tctagcaaag gcctgagtga tgaagagtat
2701 gacgagttca agagaatcag agaagaaagg aacggaaaat actccattga ggaatacctg
2761 caagaccggg atcgctacta tgaggaagtg gcagttgccc gggcaacaga ggaggacttc
2821 tgtgaagagg aggaggccaa gataagacaa agaatctttc gccccacaaa gaaacagagg
2881 aaggaagaaa ggggggtgct tggtttggtc actggctcag acatcagaaa gagaagacca
2941 gacgattttc aaccgaaggg taacctgtgg gcggacgaca ccaggagtgt ggactacaac
3001 gagagacttg atttcgaggc tcccccgagc gtctggtcaa gaatagtccc actgggcact
3061 ggctggggct tctgggtctc atcaaacctc ctgatcacaa caacacacgt cctgcctaag
3121 gggattaagg aactttttgg agttgaaatc aaacagattc aaattcataa gtctggagag
3181 ttctgcaggt tcagattccc gagaccaatt agaccagatg tcacagggct cgtgttggag
3241 gaaggcgctc cagaaggcac tgtctgctcc atactcgtaa agagacctac aggtgagatg
3301 atccccctgg cagtgaggat gggcacgcat gcatccatga aaatacaggg taggaccgtc
3361 ggtggccaga tgggaatgct cctcacaggg gcaaatgcga agaacatgga tcttggcacc
3421 ggtcctggtg actgcggttg cccttacatc tacaaacgtg gcaatgatat agttgtcgcg
3481 ggtgtccaca ccgcagcagc ccggggaggc aacactgtta tatgtgccac tcaagggcaa
3541 gatggggaag cagtccttga ggggaatgag aaccttggca cttactgcgg cgccccaatc
3601 ttgggtccag gcaaggcgcc caaacttagc acgaagacca agttctggcg ctcatcacca
3661 gacgctttgc cgccaggcac ttatgagcct gcctacttgg gaggtaagga ccccagagtg
3721 gaaaaaggac catccctgca gcaagtcatg agggaccagc taaaaccttt cacagaaccc
3781 aggggcaagc cacctagacc tgcagtctta gaagaggcca agaggacagt gatgaatgtt
3841 ctggaacaaa ccattgatcc tgctaagccg tggacctact cccaagcatg tgcctcactg
3901 gacaagacca cttccagtgg tagcccccat catgtcagga agaatgatca ttggaatggg
3961 gaatccttca ctggccccct tgcagaccaa gcatccaaag ccaacctcat gtacgagcag
4021 gccaaacatg tgcagcccgt gtacacggcc gcacttaaag atgaactagt caaaactgac
4081 aagatctaca aaaagataaa gaaaaggctc ttatgggggt cggatcttgg tacaatgatc
4141 aggtgtgcca gggcctttgg cggcctcatg gatagcatga aggcaagttg catagccctc
4201 ccatgtaggg taggaatgaa catgaatgaa gatggtccca tcatatttga caaacattct
4261 aagtataggt atcattatga tgctgactat tccaggtggg actcaaccca gcaaaggaac
4321 attctctcgg ccgctatgga agtgatggtg cggttctctg ccgaaccaga gctggcacaa
4381 gtggttgcag aggacctcct ggcacccagc caactagatg ttggcgattt cgtcatctca
4441 gtccaggagg gtctgccatc aggggttcca tgcacatcac aatggaattc aatagcacac
4501 tggatcctaa ccttgagtgc aatggcagaa gtgtcgggtc tctcaccaga tgttgttcaa
4561 gcccactcct gcttctcatt ctacggtgat gatgagatcg tcagcactga catcaacctt
4621 gatcccatga agttgacaca gaaactcaga gagtatggcc tggtccccac tcggcctgac
4681 aaaactgagg gtcccctcgt aataactgaa gatctcaccg gcctaacgtt cctgcgtagg
4741 tcaattgcac gggacccagc tgggtggttt gggaaactgg accaagactc aatcctcaga
4801 cagttgtact ggacaagggg ccccaatcat gagaacccat atgagagcat ggtccctcat
4861 tcccagcggg ccacacagct tatggccctt ctcggtgagg cttcactgca tggcccccag
4921 ttttacaaga aggttagcaa gatggtcatt aatgagatca aaagcggtgg tctggaattc
4981 tatgtgccca gacaagaggc catgttcaga tggatgagat tctctgacct cagcacatgg
5041 gagggcgatc gcaatcttgc tcccgagggt gtgaatgaag atggcgtcga atgacgctgc
5101 tccatcgaat gatggcgctg ccaacctcgt accagaggcc accaatgagg ttatggcact
5161 tgagccggtg gtgggagctt caatcgctgc tcctgtcgtc ggccaacaaa atataattga
5221 cccctggatt agagaaaatt ttgttcaggc accacagggt gagtttactg tttcaccaag
5281 gaactcacct ggtgagatgc ttctaaatct tgaattaggc cctgagctca acccttatct
5341 gagtcacttg tcccgcatgt ataatggcta tgctggtggt atgcaggttc aggtggtcct
5401 agctgggaat gcgttcacag ctggtaaaat catctttgcc gccgtcccac cacatttccc
5461 tgttgagaac attagtgcag cccaaattac aatgtgcccc catgtaattg ttgatgtaag
5521 acagcttgag ccagtgcttt tgcccctccc tgacataagg aatagattct ttcattataa
5581 tcaggaaaac accccccgga tgagacttgt ggctatgttg tacacacccc ttagagcaaa
5641 ttctggtgag gatgtgttta ctgtgtcttg cagagttctg acccgccctg cccccgactt
5701 tgagtttacg tttttggtgc caccaactgt agagtcaaag actaagccct ttacactccc
5761 tattctgact cttggagagc tgtccaactc cagattcccc gctccgatag acatgttgta
5821 cactgacccc aatgaggcaa ttgtggtgca gccacaaaat ggcaggtgca ctctagatgg
5881 aacacttcaa gggaccaccc aactggtacc cacccaaatt tgctccttta gaggcacgct
5941 aattagccag acgtcgaggt ctgcagattc aacagattca gccccacggg tgaggaacca
6001 ccctctccac gttcagctga agaacctcga tgggacacca tatgacccaa cagatgaggt
6061 gccagcagtt ttgggtgcca tagatttcaa agggactgta tttggggtcg gtagtcaaag
6121 aaacaccaca gggaactcta taggagcaac ccgcgcccat gaagtgcaca tagataccac
6181 aaaccctaga tacaccccaa agcttggctc tgtgttgatg cattctgaat ctactgattt
6241 tgatgatgga caacccatcc gctttacccc cattggcatg ggagccgatg attggcacca
6301 atgggaattg cccgaatatt ctggtcacct tactctcaat atgaatttgg cccccgcagt
6361 tgcccctgct ttccctggtg aacgcgttct cttcttcaga tcagtggtgc cgtctgctgg
6421 tggctatgga tcaggccaca tagattgcct catcccacag gaatgggttc agcatttcta
6481 ccaggaggcc gctccatcac agtctgcggt ggctcttatc agatatgtca accctgacac
6541 tggaagaaac atctttgagg caaaactgca tagagaaggg ttcatcactg tggcaaattc
6601 tggaaacaac cccatagttg tgcccccaaa tggttacttc aggtttgaag cctgggtcaa
6661 tcaattctac acactcaccc ccatgggaac tggacagggg cgcagaagag ttcaataatg
6721 gcaggagctt tcttagctgg attggcaggt gacgccataa caagtggtgt cgggtcccta
6781 atcaatgctg gggccaatgc aattaaccaa aaggtggagt atgactttaa taaacagctc
6841 caattggcat ccttcaaaca tgataaagag atgttacagt cacaagtact ggccactaaa
6901 cagctccagc aagaaatgat gaacataagg caaggggtct tgtccgctgg cggcttttcc
6961 cctacagatg ccgcgagagg tgctgtgaac gcgccgatga caaaaatttt ggattggaat
7021 ggaacaaggt acttcgcccc aaatagtatg aagacaacca gttattcggg ccagttttcc
7081 agcaaccctg tacataggca acccacttta ccccgttctg accccccaaa aatcaaggtt
7141 aatagtgatt ctgctagtgt gtatagttct gcatctactg ctccttcaca atcaacccac
7201 tcaacgacct tgactgcggg gtctagttca tctaggacaa cctcctcttc tgcagtagct
7261 tccactctat ctaggactag tgattgggtg agaggacaaa atgagaggct cagcccgttc
7321 atggatggtg ctcttcaaac aacttttgtc acaccaccat cgagcaaggc ttcttcatat
7381 gggtcggtct caaccgttcc caaagctgtt ttggactcct ggactcctat gttcaacacc
7441 cataggcagc ctctcttcgc tcatgtacgc aggcgagggg agtcacagat ttagtgaaaa
7501 gattgattag gttttctttc tttcttcttt tccttttctt tctttt
//