Typing tool
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Typing tool
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Complete norovirus genomes
| OR065073 | GII.2 | |
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| GII.P40 |
ORF1: 1..5136
ORF2: 5117..6745
ORF3: 6745..7509
LOCUS OR065073 7553 bp RNA linear VRL 06-OCT-2023
DEFINITION Norovirus GII isolate GII/Hu/US/2011/GII.2[Puntypeable]/NIH10.1
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION OR065073
VERSION OR065073.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7553)
AUTHORS Chaimongkol,N., Dabilla,N., Tohma,K., Matsushima,Y., Behrle
Yardley,A., Levenson,E.A., Johnson,J.A., Ahorrio,C., Oler,A.J.,
Kim,D.Y., Souza,M., Sosnovtsev,S.V., Parra,G.I. and Green,K.Y.
TITLE Norovirus Evolves as One or More Distinct Clonal Populations in
Immunocompromised Hosts
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7553)
AUTHORS Chaimongkol,N., Dabilla,N., Sosnovtsev,S.V. and Green,K.Y.
TITLE Direct Submission
JOURNAL Submitted (26-MAY-2023) LID, NIAID, 50 South Drive/R6318, Bethesda,
MD 20892, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: HIVE Hexagon/Heptagon v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7553
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="GII/Hu/US/2011/GII.2[Puntypeable]/NIH10.1"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="Jul-2011"
/note="genotype: GII.2"
gene 1..5136
/gene="ORF1"
CDS 1..5136
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="WIA95115.1"
/translation="MKMASNDASAATAGKTSTNSVIHNQDVNPTSNLFANMTVGLKKA
LGARPKQPAPRISSPSREGKPENNPKTPPQNKGGKTNIPPIPPPPPNGEDIVIKYTKQ
DDVVEGVPTVATVDVSPAHNTAYSVPPLDQREKVEAKEPLTGSILEMWDGEIYHYGLY
VEKGLVLGVHKPPAAISLARIELTPLSLYWRTVYTPPYLVAPETLRRLHGESFPYTAF
DNNCYSFCCWALDLNDSWLSRKFVSRTTGFFRPYQDWNRKPLPTMDEGKLKKVANVFL
CALSGLFTRPIKDLIGKLRPLNILNIVTNCDWTFPGVVEALILLAELFGVFWTPPDIS
AFVASLLGDYEMQGPEDIAVEIVPVVLGGIGMVLGFTKEKIGRLLSSAASSLRACREI
GNYGIEVVKLVMKWFFPTKSETNEMDMVRAIEDAVLDFEAIQNNHMTALLKDKNSLAT
FLRELDMEEEKARKLSTKSASPDIIGTINALLARIAAARSLVHRAKEEMSSRMRPVVI
MISGRPGIGKTHLARDLAKKMAATLSGDQRVGLVPRNGVDHWDAYKGERIVLWDDYGM
SNPVSDALRLQELADTCPLTLNCDRIENKGKVFDSDTIIITTNLANPAPLDYVNFEAC
SRRIDFLVYADSPSVDKAKRDFPGQPDMWKDAFKSDFSHIKLQLAPQGGFDKNGNTPH
GKGVMKTLTTHSLIARATGLLHERLDEFDLQGPELPVYNFDHNRVAAFRRLAADNKYG
LMETLKVGNKLKGVKTLEQLKDALKDIRIIPCRIVYNSMAYDLDSDGSGRVNVKKVAD
NKIQTNNELNSALNNLRGARVRYYIKCVQEMIYSLLQIAGAAFVTSRMTRRLNVSSIW
ARPEKQAEAAEEPPVPPTEDWTIAPANAAQEGKKGKNKSGRGKKHTAFSSKGLSDEEY
DEYKRIKDERQGKYSIEEYLHDRDRYYEELAIAKATEENFCEEEEVKIRQRIFRPSKK
QRREERATLGLVTGSEIRKRNPDDFKPKGKLWADDDRSVNYNEKIDFEAPPSLWSRIV
NFGSGWGFWVSSNLFITSTHVIPPNMTEAFGVPINQIQIHRSGEFCKMRFPKAIRTDV
SGMILEEGAPEGTVVTILIKRPTGELMPLAARMGTHATMKIQGKMLGGQMGMLLTGSN
AKNMDLGTIPGDCGCPYVYKRGNDWVVIGVHTAAARGGNTIICATQGPDGEATLEGGD
NRGTYCGAPILGPGSAPKLSTKTKFWRSSNVPLPPGTYEPAYLGGKDPRVKGGPSLQQ
VMRDQLKPFTAPRGKPPRPAILEAAKETICNVLEQTIDPPQKWSYAQACASLDKTTSS
GHPHHMKKNDKWNGESFTGVLADQASKANLMFEQGKHMQPVYTAALKDELVKTSKIYE
NVKKRLLWGSDLGTMVRCARAFGGLMDEMKANCVNLPVRVGMNMNEDGPIIFEKHSKY
KYHYDADYSRWDSTQQRHILGAALEIMVRFSAEPELAQIVSEDLLAPSVVDVGDFKIT
INEGLPSGVPCTSQWNSISHWLITLCAISEVSGLSPDVVQSNSCFSFYGDDEIVSTDI
KLDPMKLTNKLKDYGLIPTRPDKTEGPLIVRESLEGLTFLRRDVCRDPAGWYGKLDQS
SIMRQLYWTKGPNHEDPNETMIPHSQRPIQLMSLLGEAALHGPTFYKKVSKLVITELK
EGGMDFYVPRQEPMFRWMRFSDLSTWEGDRNLAPEGVNEDGVE"
mat_peptide 1..1041
/gene="ORF1"
/product="p48"
mat_peptide 1042..2139
/gene="ORF1"
/product="NTPase"
mat_peptide 2140..2676
/gene="ORF1"
/product="p22"
mat_peptide 2677..3060
/gene="ORF1"
/product="VPg"
mat_peptide 3061..3603
/gene="ORF1"
/product="Pro"
mat_peptide 3604..5133
/gene="ORF1"
/product="RdRp"
gene 5117..6745
/gene="ORF2"
CDS 5117..6745
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="WIA95116.1"
/translation="MKMASNDAAPSTDGAAGLVPESNSEAMALEPVAGVAIAAPVTGQ
TNIIDPWIRTNFVQAPNGEFTVSPRNAPGEILVNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLIFAAVPPHCPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNSFFHYNQKDDPKMRIVAMLYTPLRSNGSGEDVFTVSCRILTRPSPDFDFTYLVPP
TMESKSKPFTIPILTLGELSNSRFPVPIDQMFTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGKVTAHIHDNDHLYNITVTNLNGSPFDPTDDVPAPLGVPDFQGRIFG
VISQRDNYTHNGHDQPANRGHDAVVPTHTAKFTPKLGQIQIGTWQTDDLSVNQPVKFT
PVGLNDVEHYNQWAVPGYAGALSLNTNLAPSVAPMFPGERILFFRSYLPLKGGYGNPV
IDCLLPQEWVQHFYQEAAPSLSDVALIRYINPDTGRTLFEAKLHRAGFITVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRIQ"
gene 6745..7509
/gene="ORF3"
CDS 6745..7509
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="WIA95117.1"
/translation="MAGAFIAGLAGDMLTNSVGSLVNAGANVINQKVDFENNKYLQNA
SFSHDKEMLAAQVEATKKLQADMIGIRQGVLTAGGFSPADAARGAINAPMTKVLDWNG
TRYWAPGATATTSMSGGFTGQVMHRSTPNFKTSQAPRPAPSSGSSVRSDSTQVTNLSS
HSSGSSRSTGSTVVSSLSSSNRTRDWVNQQNLNLEPHLPGSLRTAFVTPPSSSASSTG
TVSTVPKGVLDSWTPAFNTRKQPLFAHLRRRGESNV"
ORIGIN
1 atgaagatgg cgtctaacga cgcttccgct gcgaccgctg gcaaaaccag cacaaacagt
61 gtaattcaca accaagatgt aaatcctaca tccaacctct ttgccaacat gactgttggc
121 ctaaagaagg ccctgggggc gaggccaaaa cagcccgccc ccaggatttc ctcccccagc
181 agggagggaa aacctgaaaa caatcccaaa actcctcccc aaaacaaggg aggaaagacc
241 aacatccccc caataccgcc tccaccgccc aacggggaag acatagtcat caaatacact
301 aaacaggatg atgtagttga aggggtgccc accgttgcca cggtggatgt ttcccctgca
361 cacaacaccg cctatagtgt cccccccttg gaccagaggg agaaggttga agccaaagaa
421 cccttgacag gatcaatact cgaaatgtgg gatggtgaga tctatcatta tgggctctat
481 gtggaaaagg gtttggttct tggcgtgcac aagcctccag ctgctataag ccttgcacgc
541 atagaactca ctcccctctc cctgtactgg aggacagtct acaccccacc ttatctagta
601 gcaccagaaa cactcaggag actccacggg gagtcgttcc catacacagc ttttgacaac
661 aattgctact ccttctgctg ttgggccctg gacctgaatg attcttggct cagtagaaaa
721 tttgtatcaa ggaccacagg cttcttcagg ccctatcaag attggaacag gaaaccttta
781 ccaaccatgg atgagggaaa gctcaagaaa gtggccaatg tgtttttgtg tgccctctct
841 gggctcttca ccaggcccat taaagacctc atagggaagc tgaggccact caacatactt
901 aatattgtta ccaattgtga ctggaccttc cccggagttg tggaggcact catactgctt
961 gcagaactct tcggagtttt ctggacccca ccagacattt ccgctttcgt agcgtcactt
1021 ttaggtgatt atgaaatgca gggccctgag gacatcgcgg ttgaaatcgt gccggtagtc
1081 ctcggtggca taggtatggt gcttgggttc accaaggaga aaatcggccg actgttgagc
1141 tccgccgctt cctcacttag agcatgtagg gagattggca actacgggat agaagtggtg
1201 aaattagtta tgaaatggtt cttccccacc aagagtgaaa caaacgagat ggacatggtg
1261 agggcaattg aggatgctgt gctcgacttc gaagccatac aaaacaacca catgacagca
1321 ctgctcaaag acaaaaacag tctggcaacc ttccttaggg aactagacat ggaagaggaa
1381 aaggcgcgga agctatcaac aaaatctgcg tccccagaca ttatcggcac cataaacgcc
1441 cttctagcca gaatcgccgc cgctaggtcc ctagttcata gggccaagga agagatgtca
1501 tctaggatgc gtcctgttgt aatcatgatc tctggccgac ctggtatagg caaaacgcat
1561 ctagcccgtg acctggctaa gaaaatggcg gcgacactct caggtgacca gcgagtgggg
1621 ctagtgccga ggaatggcgt tgaccattgg gacgcatata aaggagagag gatcgtgctt
1681 tgggatgact atggaatgag caaccccgtg tctgatgctc tgcggctcca ggagcttgcc
1741 gacacatgtc ccttaacact taactgtgat aggatagaaa acaaggggaa agtgtttgac
1801 agtgacacta taattatcac caccaatttg gccaaccctg cccccttaga ctatgtcaac
1861 tttgaagctt gctcccgccg aattgatttc cttgtctatg cagactctcc ctcggtggac
1921 aaggcgaaga gggacttccc tggtcaacca gacatgtgga aggatgcatt caagtcagat
1981 ttctcacaca taaaacttca gttggctcca cagggaggct ttgataaaaa tggaaacacc
2041 ccccatggga aaggtgtcat gaagacattg accacacact cactcatcgc ccgcgccacg
2101 ggccttctgc atgagagatt ggatgagttt gatctgcagg ggcccgagct acccgtgtac
2161 aattttgacc acaacagggt agctgccttc aggagactgg cggctgacaa caagtacggg
2221 cttatggaaa ccttgaaggt gggcaacaaa ttgaaaggcg tcaagaccct agaacagctt
2281 aaggatgccc taaaggacat aagaatcata ccctgtagaa tagtctacaa ctcgatggct
2341 tacgacctcg attcggatgg atcagggaga gtcaacgtca aaaaggttgc agacaacaaa
2401 attcaaacca acaacgagct caattccgcg ctcaacaatc tgcgcggtgc cagagtgaga
2461 tattatatta aatgtgtcca agagatgata tattccctcc tccagattgc tggcgcggcc
2521 ttcgtcacat caaggatgac acggagactg aatgtcagta gtatttgggc cagaccagaa
2581 aaacaagcgg aggccgctga agagccccca gtccccccaa ctgaggactg gaccatagct
2641 ccagcaaatg ctgcccagga gggtaaaaag ggtaaaaaca agagtggcag gggcaagaaa
2701 cacactgcct tctctagcaa aggcctaagt gatgaagagt atgatgagta caaaagaatc
2761 aaagatgaga ggcaagggaa atactccata gaagaatacc tccatgacag ggaccgatac
2821 tatgaagaat tggccatagc caaagcaaca gaagagaact tctgtgaaga ggaggaggtg
2881 aaaatcagac agaggatctt ccgcccgtcc aagaaacagc gcagggaaga gagggcgact
2941 ctagggttag tcacaggcag tgagataagg aagaggaacc cagacgactt caaaccaaaa
3001 ggaaaactgt gggctgatga tgaccgcagt gtaaactata atgagaaaat agattttgaa
3061 gcgcccccca gcctttggtc ccggatagtc aactttggat caggctgggg cttctgggtg
3121 tcctccaacc tattcattac ttcaacacat gtcatccccc cgaacatgac tgaggctttc
3181 ggtgtaccaa taaaccagat acaaatacac aggagtggtg agttctgcaa aatgaggttc
3241 ccaaaagcta taagaactga tgtctcaggc atgatccttg aagaaggagc tcccgaggga
3301 acagtagtga ccatactaat caaaaggccc accggtgagc tcatgccatt ggccgcccga
3361 atgggtactc atgccaccat gaaaatacag ggaaagatgc ttgggggcca gatgggtatg
3421 ctcctcacag ggtccaatgc caaaaacatg gacctaggca ccattcctgg agactgtggt
3481 tgcccctatg tgtacaagag aggcaatgac tgggtggtca taggagtgca caccgcagcc
3541 gctagaggtg gcaacaccat aatctgcgcc acccaggggc cagatggtga ggccacactt
3601 gaggggggag acaaccgtgg gacttactgt ggtgcaccaa tactcgggcc aggaagcgcg
3661 ccaaagctca gcaccaaaac aaagttttgg aggtcatcca acgtcccact cccacctggc
3721 acctatgaac ctgcttatct gggtggaaaa gacccaaggg tcaagggagg accatcactg
3781 caacaggtga tgagagacca actcaagcct ttcaccgccc ctcgagggaa gccaccaaga
3841 ccggcgatcc tggaggctgc caaagagacc atctgtaatg tgcttgagca gaccattgac
3901 ccaccccaaa aatggtctta tgctcaggct tgtgcctcac tggataagac gacatctagc
3961 ggtcaccccc accatatgaa aaagaatgac aagtggaatg gggagtcttt cactggtgtg
4021 ttagctgatc aggcctccaa agcaaacctc atgtttgagc aagggaaaca catgcaacct
4081 gtgtacactg ctgcactcaa ggatgaactc gttaaaacca gcaagatcta tgaaaatgtc
4141 aagaaaagac tcctatgggg ttcagatctg ggcacaatgg tccgctgtgc cagggctttc
4201 ggtggtctta tggatgagat gaaagctaat tgtgtgaatt taccagtcag ggttggcatg
4261 aacatgaatg aagatgggcc catcattttt gagaaacatt caaagtacaa gtaccattat
4321 gatgctgatt attctaggtg ggactcaacc caacagagac acattctggg agctgccctt
4381 gagataatgg ttagattctc agctgagcct gaactggcgc agattgtatc tgaagatctc
4441 ctagccccca gcgtagtgga cgttggtgac tttaaaatta ccataaatga aggcctgccc
4501 tctggagtac catgcacatc acagtggaac tcaatttctc attggttaat aacattatgt
4561 gccatatcag aagtttcagg gctgtcgcca gatgtggtgc aatcaaactc ctgcttctct
4621 ttctatgggg atgatgagat agtcagcact gatattaagt tagaccccat gaaactaacc
4681 aacaaattga aagactacgg actgatccca acaagaccag acaaaacaga agggccactc
4741 atagtcagag agagcctcga gggtttgact ttcctgagaa gggacgtgtg tcgagaccca
4801 gctggttggt acggaaaact tgaccaatcc tcaatcatga gacaattgta ctggaccaag
4861 ggacccaatc atgaagatcc caatgaaaca atgatcccac actcccagag acccatacag
4921 ctaatgtcat tactggggga ggcagcacta catggaccaa ccttctacaa gaaagtcagc
4981 aagttggtca ttactgagct caaagagggt ggaatggatt tttacgtgcc aaggcaggaa
5041 cctatgttta ggtggatgag attctctgac ctcagcactt gggagggcga tcgcaatctt
5101 gctcccgaag gtgtgaatga agatggcgtc gaatgacgcc gctccatcta ctgatggtgc
5161 agccggcctc gtgccagaaa gtaatagtga ggctatggct cttgaacccg tggctggtgt
5221 tgctatagca gccccggtta ctggtcaaac aaacattata gacccttgga ttagaacaaa
5281 ttttgtccag gcccccaatg gtgaattcac cgtttcccct cgaaatgccc ctggtgaaat
5341 tttagtaaat ctagaattgg gtccagaatt gaatccttat ctggcacatt tggcgaggat
5401 gtacaatggt tatgctggtg gtatggaggt gcaggtcatg ctggctggaa acgcgtttac
5461 agctgggaaa ctgatctttg ctgccgtgcc accccattgc ccagttgaaa atcttagccc
5521 acaacaaatt accatgttcc cccatgtgat tatagatgtt aggaccttgg aacccgttct
5581 gctaccactc cctgatgtca ggaacagctt cttccactac aaccagaaag atgaccctaa
5641 aatgaggatt gtagctatgc tttacacccc ccttagatca aatggttctg gtgaagatgt
5701 gttcacagtt tcatgcagga ttctaaccag gccctcccct gattttgact ttacatatct
5761 ggtgccacca acaatggaat ctaaatcgaa accattcacc ataccaatcc tcacacttgg
5821 tgagttgtcc aattccagat ttcctgtgcc catagatcag atgttcacca gccccaatga
5881 ggttatatca gtgcagtgtc aaaacggaag gtgcacttta gatggggagc tccagggaac
5941 aacacagctc caggttagtg gcatttgtgc attcaagggg aaggtgaccg ctcacataca
6001 tgacaatgac cacctctaca acatcactgt cacaaatctg aatgggtccc cttttgatcc
6061 cactgacgat gtccctgccc cgttaggtgt accagatttt cagggaagaa ttttcggtgt
6121 catcagccaa agagacaact atacccacaa tgggcatgat caacctgcaa ataggggtca
6181 cgacgccgtg gtccccaccc acacagcaaa attcactcca aaattgggtc agatccaaat
6241 tggcacctgg cagactgacg acctatcagt caatcagcct gttaaattca ctccagttgg
6301 cctcaatgat gtggaacatt acaaccagtg ggcagtcccc gggtatgctg gtgccctgag
6361 cctgaacaca aaccttgccc cttccgttgc accgatgttt ccgggggagc ggatactctt
6421 cttcagatct taccttcccc ttaaaggtgg ttatggcaac ccagtcatag actgcctgct
6481 acctcaggaa tgggtgcaac acttctacca ggaggccgcc ccctcactaa gtgatgtggc
6541 tctcattagg tacatcaatc cagacactgg tcggactttg tttgaggcca agctccacag
6601 agctggtttc ataacagtct caagcaacac cagcgcccca gtggtagtgc ccgccaacgg
6661 gtatttcaga tttgattctt gggttaatca gttttactct ctcgccccca tgggaactgg
6721 gaatgggcgc agaaggattc agtaatggca ggagctttta ttgcaggatt ggctggtgat
6781 atgttaacaa attctgtagg gtctttagtt aatgcaggtg ctaatgtaat taatcagaaa
6841 gttgattttg agaataataa atatttacaa aatgcatcat tctcccatga caaagagatg
6901 ctggctgcac aagttgaggc aacaaagaaa ctccaggctg acatgatcgg cattaggcag
6961 ggggtcttga ccgctggcgg cttttccccc gctgacgccg cgagaggggc aatcaacgca
7021 cccatgacca aggttttgga ttggaacggc acgcggtact gggcaccggg cgccaccgcc
7081 acaacttcaa tgtctggtgg cttcaccggc caggttatgc acagatccac accaaatttt
7141 aaaacctccc aggctcctag acccgctccc agcagtggat cgtctgtgag atcagattca
7201 acccaggtta ccaacctgag ctctcattcc tcagggtctt cacgatccac tgggtccaca
7261 gttgttagct ctctgtcatc ttccaacagg actagagatt gggtcaacca acagaacctg
7321 aacttggagc cccatttgcc tgggtccctc aggacagcct ttgtcactcc accatctagc
7381 agtgcttcta gcacaggcac agtctcaacc gtgccgaagg gtgttttgga ctcctggaca
7441 cctgcgttca acacccgcaa gcagccgctg tttgctcacc ttcgtagaag gggggagtca
7501 aatgtttagt gaaaagatta tttgattaga tttgtttgat tggaaaatct ttt
//