Typing tool
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Typing tool
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Complete norovirus genomes
| OR051903 | GII.6 | |
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| GII.P7 |
ORF1: 1..5094
ORF2: 5075..6718
ORF3: 6718..7497
LOCUS OR051903 7522 bp RNA linear VRL 06-OCT-2023
DEFINITION Norovirus GII isolate GII/Hu/US/2013/GII.6[P7]/NIH29.1
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION OR051903
VERSION OR051903.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7522)
AUTHORS Chaimongkol,N., Dabilla,N., Tohma,K., Matsushima,Y., Behrle
Yardley,A., Levenson,E.A., Johnson,J.A., Ahorrio,C., Oler,A.J.,
Kim,D.Y., Souza,M., Sosnovtsev,S.V., Parra,G.I. and Green,K.Y.
TITLE Norovirus Evolves as One or More Distinct Clonal Populations in
Immunocompromised Hosts
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7522)
AUTHORS Chaimongkol,N., Dabilla,N., Sosnovtsev,S.V. and Green,K.Y.
TITLE Direct Submission
JOURNAL Submitted (26-MAY-2023) LID, NIAID, 50 South Drive/R6318, Bethesda,
MD 20892, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: HIVE Hexagon/Heptagon v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7522
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="GII/Hu/US/2013/GII.6[P7]/NIH29.1"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="Nov-2013"
/note="genotype: GII.6"
gene 1..5094
/gene="ORF1"
CDS 1..5094
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="WHW95053.1"
/translation="MKMASNDASAAFGNQNSVNDSINTAPSNKEEVGAFSNIKVGFKK
ILGAVPKGTKAPSSDQHCPTVKIGTKTLTVPPEPPNGEDAVQFDVKSETVRGLPDLTT
VQNEHENTPYTVPPLSEREHRPATEPLPGTILEMWDGEFYHYSVYVSGGKALGVHKPP
AAISLATIELTPISLYWRPVYTPNYLVCPDTLKGLAGEKFPYTAFSNNCYNFCCWVLE
LNDTWLSRRSISRTTGFFKPYQSWNRKPLPTVDDGKIKKVANAILCALGSLFSKPIKD
LLGKLKPLNLLHLLASCDWTFAGIVETVILMAELFNIFWTPPDVSSFIASLIGDFELQ
GPEDLAVELVPVVMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMK
WFFPKKEEKAEMETLRAIEDAVLDMEAIGNNHLTTLLKDKDSLTAFMKTLDLEEEKAR
KLSTKSSSPDIVGTINAILARIAAARSLLHKAKEEMFSRIRPVVVMISGRPGIGKTHM
ARHLAKSIANTMSGDQRVGLVPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALTLQEL
ADTCPVTLNCDRIENKGKMFDSDVIIITTNLVNPAPLDYVNFEACSRRVDFLVYAESP
EIEKVKRDFPGQPDMWKDHFKSDFSHIKLTLAPQGGFDKNGNTPHGKGTMRSLTQGSL
TARVAGLVHERRDEFQLQGTDLQTYNFDTNRVSAFRKLAADNKYGIMETMRVGTALKS
VKTLEDLKVALRDVKFNECEIIYRNSKYRVSSNGKGSVSVDKIEDQTSQTANEVGAAL
LRLRQARARYYVSCFQDLVYTLIQVAGASFVVNRISKRFCWERWVKPTETQETSESEK
EVAQGRWEIEPKDTEPEGKKGKNKKGRGKKHTAFSSKGLSDEEYDEFKRIREERNGKY
SIEEYLQDRDRYYEEVAVARATEEDFCEEEEAKIRQRIFRPTKKQRKEERGVLGLVTG
SDIRKRRPDDFQPKGNLWADDTRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSNL
LITTTHVLPKGIKELFGVEIKQIQIHKSGEFCRFRFPRPIRPDVTGLVLEEGAPEGTV
CSILVKRPTGEMIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDCG
CPYIYKRGNDIVVAGVHTAAARGGNTVICATQGQDGEAVLEGNESLGTYCGAPILGPG
KAPKLSTKTKFWRSSPDALPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEPRG
KPPRPAVLEEAKKTVMNVLEQTIDPAKPWTYSQACASLDKTTSSGSPHHVRKNDHWNG
ESFTGPLADQASKANLMYEQAKHVQPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGT
MIRCARAFGGLMDSMKASCIALPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDST
QQRSILSAAMEVMVRFSAEPELAQVVAEDLLAPSQLDVGDFVILVQEGLPSGVPCTSQ
WNSIAHWILTLSAMAEVSGLSPDVVQAHSCFSFYGDDEIVSTDINLDPMKLTQKLREY
GLVPTRPDKTEGPLVITEDLTGLTFLRRSIARDPAGWFGKLDQDSILRQLYWTRGPNH
ENPYESMVPHSQRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEAM
FRWMRFSDLSTWEGDRNLAPEGVNEDGVE"
mat_peptide 1..1002
/gene="ORF1"
/product="p48"
mat_peptide 1003..2100
/gene="ORF1"
/product="NTPase"
mat_peptide 2101..2619
/gene="ORF1"
/product="p22"
mat_peptide 2620..3018
/gene="ORF1"
/product="VPg"
mat_peptide 3019..3561
/gene="ORF1"
/product="Pro"
mat_peptide 3562..5091
/gene="ORF1"
/product="RdRp"
gene 5075..6718
/gene="ORF2"
CDS 5075..6718
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="WHW95054.1"
/translation="MKMASNDAAPSNDGAANLVPEANNEVMALEPVVGASIAAPVVGQ
QNIIDPWIRENFVQAPQGEFTVSPRNSPGEMLLNLELGPELNPYLSHLSRMYNGYAGG
MQVQVVLAGNAFTAGKIIFAAVPPHFPVENISAAQITMCPHVIVDVRQLEPVLLPLPD
IRNRFFHYNQENTSRMRLVAMLYTPLRANSGEDVFTVSCRVLTRPAPDFEFTFLVPPT
VESKTKPFTLPILTLGELSNSRFPAPIDMLYTDPNEGIVVQPQNGRCTLDGTLQGTTQ
LVPTQICAFRGTLIGQTSRSSDSTDSAPRRRDHPLHVQLKNLDGTQYDPTDEVPAVLG
AIDFKGTVFGVASQRDVSGQQVGATRAHEVHINTTDPRYTPKLGSILMHSESDDFVTG
QPVRFTPIGMGDNDWHQWELPDYSGHLTLNMNLAPAVAPAFPGERILFFRSVVPSAGG
YGSGQIDCLIPQEWVQHFYQEAAPSQSAVALIRYVNPDTGRNIFEAKLHREGFITVAN
SGNNPIVVPPNGYFRFEAWVNQFYTLTPMGTGQGRRRNQ"
gene 6718..7497
/gene="ORF3"
CDS 6718..7497
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="WHW95055.1"
/translation="MASAFLAGLAGDVITNGVGSLINAGANAVNQKVEYDFNKQLQMA
SFKHDKEMLQSQVLATKQLQQEMMNIRQGVLTAGGFSPADAARGAVNAPMTKILDWNG
TRYWAPNSMKTTSYSGQFSSSPVHKSPAPSLHTASPKSRLQNDSASVYSFPSSVSSQS
THSTVLSVGTGSSRSIPTSTATPTLSRTSDWVRGQNERLSPFMDGALQTAFVTPPSSR
ASSNGTVSTVPKAVLDSWTPMFNTHRQPLFAHPRRRGESQV"
ORIGIN
1 atgaagatgg cgtctaacga cgcttccgct gcctttggca accaaaactc tgtcaatgac
61 agtatcaaca ccgccccttc caataaagaa gaggttggtg cattctccaa catcaaagtt
121 ggttttaaga aaatactggg tgccgttccc aaggggacca aagcacccag tagtgatcag
181 cactgcccca cagttaagat cgggaccaaa acattaacag ttccccctga gcccccaaat
241 ggtgaagacg ccgtgcagtt tgatgtgaag tcggaaactg tgcgtgggct accagacttg
301 acaacggtgc agaatgaaca cgaaaacaca ccatacactg tccccccatt gagtgaaagg
361 gagcacagac cagccactga gccgcttcct ggtacaatac tggagatgtg ggatggtgaa
421 ttctaccatt actccgtata cgtcagcggt ggcaaagccc taggggttca caagccccct
481 gcagcgataa gcctcgcgac gatagagctc acacccatat ctctttattg gaggcccgtt
541 tacaccccaa actatctggt ctgtccagac acgttgaaag gcctcgctgg tgagaagttc
601 ccctacacgg ccttcagcaa caactgttac aacttctgtt gctgggtgct cgagctcaat
661 gacacgtggc ttagcaggag aagcatctcc aggaccaccg gcttcttcaa accatatcag
721 tcttggaata ggaaacccct tccaaccgtt gatgatggaa agattaaaaa ggtggccaac
781 gcgattcttt gcgcacttgg atcactgttt tcaaaaccaa tcaaggacct attgggcaaa
841 cttaaaccat tgaacttgct gcacttgctc gcatcatgtg actggacgtt tgcgggtata
901 gtagagacag ttatcctaat ggcggaactt ttcaacatct tttggacacc gccagatgtt
961 tccagcttca tagcctccct gataggcgat tttgaactgc aagggcctga ggacctggct
1021 gtggagcttg tccccgtggt catgggtggc ataggaatgg ttctcggctt cactgctgag
1081 aagataggcc gcatgctatc atccgctgca tcaacactgc gagcatgtaa agacttgggg
1141 aattatgccc ttgacatatt gaaactggtt atgaagtggt tcttcccaaa gaaagaagag
1201 aaagccgaga tggaaacctt aagggcgatc gaggatgctg tcctggatat ggaagctata
1261 ggaaacaacc atctcacaac cctccttaag gacaaggaca gcctcacggc tttcatgaag
1321 actctggacc tagaagagga gaaggcaagg aagctgtcca ccaagtcatc ctcgccagat
1381 atcgtcggca ctattaatgc catactggcc agaatagctg ctgccaggtc cctcttacac
1441 aaggccaaag aagaaatgtt tagcaggatt agacctgtgg ttgttatgat ctctggtaga
1501 cctggcatcg gaaaaaccca catggcaagg cacttggcta agagtatcgc caacaccatg
1561 agcggcgacc agagagtggg gctcgtccca cgcaacgggg tcgatcattg ggacgcctac
1621 aggggagaga gggtggtctt atgggatgat tatggcatgg gaaaccctgt caaagatgcc
1681 ctaacactgc aagagttggc tgacacctgc ccagtaaccc taaactgcga caggattgag
1741 aacaagggga agatgttcga cagtgatgtc atcataatca cgaccaactt agtcaaccca
1801 gcgcccctcg attatgtgaa cttcgaggca tgctccagaa gggtcgactt tctggtctac
1861 gcagagtcac cagagattga gaaggttaag agagatttcc ccggccaacc tgacatgtgg
1921 aaggaccatt ttaagtcaga cttttcccac ataaaactga ctctagcccc acagggcgga
1981 tttgacaaga atggcaacac cccccatggt aagggcacca tgcgatccct aacccagggg
2041 tccctgactg caagggttgc aggtcttgtt catgagagga gagacgagtt tcagctccag
2101 ggaaccgacc ttcaaacata caactttgac accaacaggg tctctgcatt taggaagctg
2161 gccgcagaca acaagtatgg gatcatggag acaatgagag tgggcacggc gcttaagagt
2221 gtcaagacat tagaagatct gaaagtcgcc ctgagggatg tgaaattcaa tgagtgtgag
2281 ataatttaca ggaactccaa ataccgagtc tcttccaatg gtaaaggttc tgtctctgtt
2341 gacaaaattg aggaccaaac atcccagact gcaaacgaag tgggtgcagc acttcttaga
2401 ctcaggcagg caagagccag atactatgtc agctgcttcc aagatcttgt ctacactctg
2461 atacaggtcg ccggagcatc attcgttgtc aacaggatct ctaaaagatt ctgctgggag
2521 agatgggtca agccaactga gacccaggaa acgagtgaat ccgaaaagga agtagcccaa
2581 ggcagatggg agattgaacc caaggacaca gaaccagaag gtaagaaggg caagaacaag
2641 aaaggaagag gcaagaaaca cacagctttc tccagcaaag gcctgagtga tgaggagtat
2701 gacgagttca agagaatcag agaagaaagg aatggaaaat actccattga ggagtacctg
2761 caagaccggg atcgctacta tgaggaagtg gcagttgccc gggcgacaga ggaggacttc
2821 tgtgaagagg aggaggccaa gataaggcaa agaatcttcc gccccacaaa gaaacagagg
2881 aaggaagaaa ggggggtgct tggtttggtc actggctcag acatcaggaa gaggagacca
2941 gacgattttc aaccgaaggg caatctgtgg gcagacgaca ccaggagtgt ggactacaac
3001 gagagacttg atttcgaggc tcccccgagt gtctggtcaa gaatagtccc attgggcact
3061 ggctggggtt tctgggtctc atccaacctc ctgatcacaa caacacacgt cctgcctaag
3121 ggaattaaag aactttttgg agttgaaatc aaacagattc aaattcataa gtctggagag
3181 ttctgcaggt ttaggttccc gagaccaatc agaccagatg tcacagggct cgtgttggag
3241 gaaggtgctc cagagggcac tgtctgctcc atactcgtga agagacccac aggtgagatg
3301 atccccctgg cagtgaggat gggcacgcat gcatccatga aaatacaggg caggaccgtc
3361 ggtggccaga tgggaatgct cctcacgggg gcaaatgcga agaacatgga tcttggcact
3421 ggtcctggtg actgcggttg cccttacatc tacaaacgtg gcaatgatat agttgtcgcg
3481 ggtgtccaca ccgcagcagc ccggggaggc aatactgtca tatgtgccac tcaagggcaa
3541 gatggggagg cagtccttga gggaaatgaa agccttggca cttactgtgg tgccccaatt
3601 ttgggtccag gcaaggcgcc caaacttagc acgaagacca aattctggcg ttcatcacca
3661 gacgctttgc cgccaggcac ttatgagcct gcctacttgg ggggcaagga ccccagagtg
3721 gaaaaaggac catccctgca gcaagtcatg agggaccagc taaaaccttt cacagaaccc
3781 agaggcaaac cacctagacc tgcagtctta gaagaagcca aaaagacggt tatgaatgtt
3841 ctggaacaaa ccattgaccc tgctaagcca tggacctatt cccaagcatg cgcctctctg
3901 gacaagacca cttccagtgg tagcccccat catgtcagga aaaatgatca ctggaatggg
3961 gaatctttca ctggccccct cgcagaccaa gcatccaaag ccaacctcat gtacgaacag
4021 gccaaacatg tgcaacccgt gtacacggcc gcactcaaag atgagctagt caaaactgat
4081 aagatctaca aaaagataaa gaaaaggctc ttatgggggt cggatcttgg tacaatgatc
4141 aggtgtgcca gggcctttgg cggtctcatg gatagcatga aggcaagttg catagccctc
4201 ccatgtaggg taggaatgaa catgaatgaa gatggtccca tcatatttga caaacactct
4261 aagtataggt accactatga tgctgactat tccaggtggg actcaaccca gcaaaggagc
4321 atcctctcgg ccgctatgga agtgatggtg cggttctctg ccgaaccaga gctggcacaa
4381 gtggttgcag aggacctcct ggcacctagc cagctagatg ttggcgactt tgtcatctta
4441 gtccaggagg gtctgccatc aggggttcca tgcacatcac aatggaattc aatagcacat
4501 tggatcctga ccttgagtgc aatggcagaa gtgtcgggtc tctcaccaga tgttgtccaa
4561 gcccactcct gtttctcatt ctacggtgat gatgagatcg tcagcactga catcaacctc
4621 gatcccatga agttgacaca gaaactcaga gagtatggtc tggtccccac tcgacctgat
4681 aaaactgagg gccccctcgt gataactgaa gacctcaccg gcctaacgtt cctgcgcagg
4741 tcaattgcac gggacccagc tgggtggttt ggaaagttgg accaagactc aatcctcaga
4801 cagttgtact ggacaagggg ccccaatcat gagaacccat atgagagcat ggtccctcat
4861 tcccaacggg ccacacagct catggccctt ctcggcgagg cttccctgca tggcccccag
4921 ttttacaaga aggttagcaa gatggtcatc aatgaaatca aaagtggtgg tctggaattc
4981 tatgtgccca gacaagaggc tatgttcaga tggatgagat tctctgacct cagcacatgg
5041 gagggcgatc gcaatcttgc tcccgagggt gtgaatgaag atggcgtcga atgacgctgc
5101 tccatcgaat gatggtgctg ccaacctcgt accagaggcc aacaatgagg tcatggcact
5161 tgaaccggtg gtgggagcct caatcgcagc tcctgtcgtc ggccaacaga acataattga
5221 cccctggatt agagaaaatt ttgtccaagc accacagggc gagtttaccg tctcaccgag
5281 gaactcgcct ggtgagatgc tattaaatct tgaactaggc ccagaactta acccctatct
5341 aagtcacctg tcccgtatgt ataatgggta tgctggtggc atgcaggttc aggtggtcct
5401 agctgggaat gcgttcacag ctgggaaaat catctttgcc gccgtaccac cacattttcc
5461 cgtagagaac atcagtgcag ctcaaataac tatgtgtccc catgtaattg ttgatgtgag
5521 acagcttgaa ccagtacttc tgcccctccc tgacataagg aataggttct ttcattacaa
5581 tcaggagaac acctcccgga tgagacttgt ggccatgctt tatacccccc tgagggccaa
5641 ctctggtgaa gatgtgttta ctgtttcctg tagggtcttg acccgtcctg cccctgattt
5701 tgagtttact ttcttggtac caccgactgt tgaatcgaag actaaacctt tcacactgcc
5761 catattaact cttggtgagc tatctaactc cagattccca gccccaatag atatgttgta
5821 cactgaccca aatgagggga ttgtggtcca accacaaaat ggtaggtgca ctcttgatgg
5881 cactctgcaa ggcaccacac aactggtccc cacccaaatt tgtgctttca ggggcacact
5941 aattggccaa acatcaagat cttcagactc aaccgactca gcccctcgga gaagggatca
6001 cccactccat gtgcaattaa agaaccttga tggcacgcag tacgacccaa ctgatgaagt
6061 gccagcagtc cttggtgcca ttgacttcaa ggggactgtc tttggggtgg ctagtcagag
6121 agatgtgtca gggcaacaag tgggagcaac tcgagctcat gaagtgcaca tcaacacaac
6181 cgatcctagg tacacaccaa aactgggatc cattctcatg cactcagagt cggacgactt
6241 tgtgactgga cagccggtcc gcttcacacc cataggaatg ggtgacaacg actggcacca
6301 gtgggagctg cccgactact ctggacacct aaccctgaac atgaaccttg ccccagcagt
6361 cgctcctgct tttccgggcg agaggattct tttcttcagg tcagtagtcc cgtctgctgg
6421 tggctatggg tctggacaaa tagactgcct cataccacag gagtgggttc agcatttcta
6481 ccaggaagct gcaccatccc aatctgccgt ggcactcatc aggtatgtca atcctgacac
6541 aggcagaaac atctttgagg ctaaattgca cagggaaggt ttcatcaccg tggcaaattc
6601 tggcaacaac cccatcgttg tcccccctaa tgggtatttt aggtttgagg cttgggtgaa
6661 tcaattttac actttgaccc ccatgggaac tggtcagggg cgtaggagga atcaataatg
6721 gccagtgctt ttcttgcagg tcttgctggc gacgtcataa caaatggcgt tggatctcta
6781 ataaatgctg gagctaatgc agttaatcag aaagttgaat atgattttaa taaacagctt
6841 caaatggcat cattcaaaca tgataaagag atgttgcaat cgcaagtgtt ggcaaccaag
6901 cagttgcagc aggagatgat gaacataagg cagggggtgt tgaccgctgg cggcttctcc
6961 cccgcggatg ctgctagagg ggccgtcaat gccccaatga caaagattct ggactggaat
7021 ggcaccaggt attgggcacc aaacagcatg aaaaccacaa gttattcagg acagttttct
7081 agcagccctg ttcataagtc tcctgcccct tctttgcaca ctgcttcacc aaagagtaga
7141 ttgcaaaatg attctgctag tgtatatagt ttcccttcct ctgtctcttc acaatcaact
7201 cattcaacag tgttgtcagt aggaaccggt tcttccaggt ccatccccac atccacagcg
7261 acccctacct tgtctagaac cagcgactgg gttaggggac agaatgagag gctcagcccg
7321 tttatggatg gtgctctcca aactgccttt gtcacacctc catcgagcag agcttcttca
7381 aatggtacgg tctcaaccgt tcccaaagct gttttggact cctggacccc tatgtttaac
7441 acacataggc agcctctctt cgcccatcca cgtaggcgag gggagtcaca agtttagtga
7501 aaagagtgat taggatttct cc
//