Typing tool
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Typing tool
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Complete norovirus genomes
| OR051787 | GII.4 New Orleans | |
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| GII.P4 New Orleans |
ORF1: 1..5100
ORF2: 5081..6700
ORF3: 6700..7506
LOCUS OR051787 7551 bp RNA linear VRL 06-OCT-2023
DEFINITION Norovirus GII isolate GII/Hu/US/2011/GII.4NewOrleans[P4]/NIH11.1
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION OR051787
VERSION OR051787.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7551)
AUTHORS Chaimongkol,N., Dabilla,N., Tohma,K., Matsushima,Y., Behrle
Yardley,A., Levenson,E.A., Johnson,J.A., Ahorrio,C., Oler,A.J.,
Kim,D.Y., Souza,M., Sosnovtsev,S.V., Parra,G.I. and Green,K.Y.
TITLE Norovirus Evolves as One or More Distinct Clonal Populations in
Immunocompromised Hosts
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7551)
AUTHORS Chaimongkol,N., Dabilla,N., Sosnovtsev,S.V. and Green,K.Y.
TITLE Direct Submission
JOURNAL Submitted (26-MAY-2023) LID, NIAID, 50 South Drive/R6318, Bethesda,
MD 20892, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: HIVE Hexagon/Heptagon v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7551
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="GII/Hu/US/2011/GII.4NewOrleans[P4]/NIH11.1"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="Nov-2011"
/note="genotype: GII.4"
gene 1..5100
/gene="ORF1"
CDS 1..5100
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="WHW76521.1"
/translation="MKMASNDASAAAVANSNNDTAKSSSDGVLSSMAVTFKRALGARP
KQPPPREKSQRPPRPPTPELVKSIPPPPPNGEDEIVVSYSVKDGVSGLPDLSTVRQPE
ESNTAFSVPPLNQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAIS
LARIELAPLSLYWRPVYTPQYLISPDTLKKLSGETFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTTDDSKIKKVANIFLCALSSLFTRPIKDIIGK
IRPLNILNILASCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPED
LAVELVPVVMGGIGLVLGFTKEKVGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEANELAIVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINALLARIAAARSLVHRAKEELSSRPRPVVLMISGRPGIGKTHLAREV
AKRIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEK
AKRDFPGQPDMWKNAFSSDFSHIKLALAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERLDEFELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMRVGKQLKDVKTM
PELKQALKNVSIKKCQIVYSGCTYTLESDGKGNVKVDRIQSAAVQTNNELTGALHHLR
SARIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQDLWSKPQVENTEETTSKDGC
PKPKDDEEFVISSDDIKAEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPDDFKPKGKLWADDDRNVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSP
SLFITSTHVIPQGAKEFFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRSTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILG
PGSAPTLSTKTKFWRSSTASLPPGTYEPAYLGGKDPRVKGGPSLQQVMREQLKPFTEP
RGKPPKPSVLEAAKKTIINVLEQTIDPPEKWSFAQACASLDKTTSSGHPHHMRKNDCW
NGESFTGKLADQASKANLMFEEGKNMTPVYTAALKDELVKTDKIYGKIKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPIRVGMNMNEDGPIIFERHSRYTYHYDADYSRWD
STQQRAVLAAALEIMVKFSPEPHLAQVVAEDLLSPSVVDVGDFTISINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTNLSPDTIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLR
EYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGP
NHGDPSETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide 1..990
/gene="ORF1"
/product="p48"
mat_peptide 991..2088
/gene="ORF1"
/product="NTPase"
mat_peptide 2089..2625
/gene="ORF1"
/product="p22"
mat_peptide 2626..3024
/gene="ORF1"
/product="VPg"
mat_peptide 3025..3567
/gene="ORF1"
/product="Pro"
mat_peptide 3568..5097
/gene="ORF1"
/product="RdRp"
gene 5081..6700
/gene="ORF2"
CDS 5081..6700
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="WHW76522.1"
/translation="MKMASSDANPSDGSTANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLDPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHISGSHNYTMNLASQNWNSYDPTEEIPAPLGTPDFVGKIQGVL
TQTTRTDGSTRGHKATVYTGSADFSPKLGRVQFATDTDNDFETNQNTKFTPVGVIQDG
GTHQNEPQQWELPSYSGRNIHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMNLDC
LLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHRSGYVTVAHTGQHDLVI
PPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
gene 6700..7506
/gene="ORF3"
CDS 6700..7506
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="WHW76523.1"
/translation="MAGAIFAGLASDVLSSGLSSLINAGAGAINQTIEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLHAQIEATKKLQQEMMRVKQAMLLEGGFSETDAARGAIN
APMTKTLDWSGTRYWAPDARTTTYNAGRFSTPQPSGAPPGRANLRATVPARGSSSTSS
NSSIATSVYSNQTTSTRLGSTAGSGTSVSSLPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEVLDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 atgaagatgg cgtctaacga cgcttccgct gccgctgttg ctaacagcaa caacgacacc
61 gcaaaatctt caagtgacgg agtgctctct agcatggctg tcacttttaa acgagccctc
121 ggggcgcggc ctaaacagcc tcccccgagg gaaaaatcac aaagaccccc acggccacct
181 actccagaac tggttaaaag tattcctcct cccccaccca acggagagga tgaaatagtg
241 gtttcttata gtgtcaaaga tggtgtttcc ggcttgcctg acctttccac cgtcaggcaa
301 ccggaagaat ctaacacggc cttcagtgtc cctccactca atcagaggga gaacagagat
361 gctaaggaac cactcactgg aacaattctg gaaatgtggg acggggaaat ctaccattat
421 ggcctgtatg tggagcgagg tcttgtactg ggtgtgcaca aaccaccagc tgccatcagc
481 ctcgctagga ttgagctagc accactctcc ttatactgga gacctgtgta cactcctcag
541 tacctcatct ccccagacac tctcaagaaa ttgtccggag aaacgttccc ctacacagcc
601 tttgacaaca actgttatgc cttttgttgc tgggtcctgg acctaaatga ctcgtggctg
661 agcaggagaa tgatccagag aacaactggt ttcttcaggc cctaccaaga ctggaatagg
721 aaaccccttc ccactacgga tgactccaaa ataaagaagg tagctaacat attcctgtgt
781 gctctgtcct cgctgttcac cagacccata aaagatataa tagggaagat aagacctctt
841 aacatcctca acatcttagc ctcatgtgat tggacttttg caggtatagt ggagtccctg
901 atactcttgg cagaactctt tggagttttc tggacacccc cagatgtgtc tgcgatgatt
961 gcccccttac tcggtgacta cgagctacaa ggacctgagg accttgcagt tgagctcgtc
1021 cccgtggtga tggggggaat tggtttggtg ctaggattca ccaaagagaa ggttgggaaa
1081 atgttgtcat ctgctgcgtc caccttgaga gcttgtaaag accttggtgc atatgggctg
1141 gagatcctaa agttggtcat gaagtggttc ttcccgaaga aggaagaggc aaatgagctg
1201 gctatagtga gatctatcga ggatgcagtc ttggatctcg aggcaattga aaacaaccat
1261 atgaccacct tgctcaaaga caaagacagt ctggcaacct atatgagaac acttgacctt
1321 gaggaggaga aagccaggaa actctcaacc aagtctgcct cacccgatat cgtgggcaca
1381 atcaacgccc tcctggcgag aatcgctgcc gcacgctctc tggtacaccg agcgaaggag
1441 gagctttcca gcagaccaag acctgtggtg ttgatgatat caggcaggcc aggaataggg
1501 aagacccacc tcgctaggga agtggctaag agaatcgcag cctcccttac aggagaccag
1561 cgtgtgggcc tcatcccacg caatggcgtc gaccattggg atgcgtacaa gggggagagg
1621 gtcgtcctat gggacgatta tggaatgagc aaccctattc acgatgccct caggctgcaa
1681 gaactcgctg acacttgtcc cctcactcta aactgtgaca ggatcgaaaa caaaggaaag
1741 gtctttgaca gcgatgtcat cattatcacc actaatctgg ccaacccagc accactggac
1801 tatgtcaact ttgaagcatg ctcgaggcgc atcgacttcc tcgtgtatgc agaagcccct
1861 gaagtcgaaa aggcgaagcg tgacttccca ggccagcctg acatgtggaa gaacgctttc
1921 agttctgact tctcacacat aaaattagca ctggccccac agggtggttt cgacaagaac
1981 gggaacaccc cacacggaaa gggcgttatg aagactctca ccactggctc ccttattgcc
2041 cgggcatcag ggctactcca tgagaggtta gatgaatttg aactgcaggg cccagccctc
2101 accaccttca atttcgatcg caataaggtg cttgccttta gacagcttgc tgctgaaaac
2161 aaatatggat tgatggacac aatgagagtt gggaaacagc tcaaggatgt caaaaccatg
2221 ccagagctca aacaagcact caagaatgtc tcaatcaaga agtgccaaat agtgtatagt
2281 ggttgcacct acacacttga gtctgatggc aagggcaatg tgaaagttga cagaatccaa
2341 agcgccgccg tgcagaccaa caatgagctg actggtgccc tacaccattt gaggagcgcc
2401 agaatcagat actatgtcaa gtgtgtccag gaggccctgt attccatcat ccaaatcgct
2461 ggggctgcat ttgtcaccac gcgcattgcc aagcgcatga acatacaaga cctatggtcc
2521 aagccacaag tggaaaacac agaggagact accagcaagg atgggtgccc aaaacctaag
2581 gacgatgagg agtttgtcat ttcatccgac gacatcaaag ctgagggtaa gaaagggaag
2641 aacaagactg gccgcggcaa gaagcacaca gcattttcaa gcaaaggcct tagtgatgaa
2701 gagtacgatg agtacaagag gattagagaa gaaaggaatg gcaagtactc catagaagag
2761 taccttcagg acagggacaa atactatgag gaggtggcca ttgccagggc gactgaggaa
2821 gacttctgtg aagaggagga ggccaagatc cggcaaagga tctttaggcc aacaaggaaa
2881 caacgcaagg aggaaagagc ctccctcggt ctggtcacag gctctgaaat taggaaaaga
2941 aacccagatg acttcaaacc caaagggaaa ttgtgggctg acgatgacag gaatgtagac
3001 tacaatgaga aactcagttt tgaggcccca ccaagcatct ggtcgagaat agtcaacttt
3061 ggttcaggct ggggattttg ggtctccccc agtctgttca taacatcaac ccatgtcata
3121 ccccagggcg cgaaggagtt ctttggagtc cccatcaaac aaatacaggt acacaagtcg
3181 ggcgagttct gtcgccttag attcccaaaa ccaatcagga ctgatgtgac gggcatgatc
3241 ttagaagaag gcgcacctga gggcaccgtg gccacgctac tcatcaaaag gtccactggg
3301 gaactcatgc ccctagcagc taggatgggg acccatgcga ccatgaagat ccaagggcgc
3361 actgttggag gccagatggg tatgcttctg acaggttcca acgccaagag catggacctg
3421 ggtactacac caggtgattg tggctgcccc tatatctaca agagaggtaa tgactatgtg
3481 gtcattgggg tccacacggc tgccgcacgt ggggggaaca ctgtcatatg tgccacccag
3541 gggagtgagg gagaggctac acttgaaggt ggtgacaaca agggaacata ctgtggtgca
3601 ccaatcctag gcccagggag tgccccaaca cttagcacca aaaccaaatt ctggagatcg
3661 tccacagcat cactcccacc tggcacctat gaaccagcct atcttggtgg caaggaccct
3721 agggtcaagg gtggtccttc actgcagcaa gtcatgaggg aacagttgaa gccattcaca
3781 gagcccaggg gcaagccacc aaaaccaagt gtattagaag ctgccaagaa gaccatcatc
3841 aatgtccttg agcaaacaat tgatccacct gagaaatggt cgttcgcaca agcttgcgcg
3901 tcccttgaca agaccacttc cagtggtcat ccgcaccaca tgcggaaaaa cgactgctgg
3961 aacggggagt ccttcacagg caagctggca gaccaagctt ccaaggccaa cctgatgttt
4021 gaagaaggga agaacatgac cccagtctac acagctgcgc tcaaggatga gttagttaaa
4081 actgacaaaa tttatggtaa gatcaagaag aggcttctct ggggctcgga cttggcgacc
4141 atgatccggt gtgctcgagc attcggaggc ctaatggatg aactcaaagc acactgtgtc
4201 acacttccta ttagagttgg catgaatatg aatgaggatg gccccatcat cttcgagagg
4261 cattccaggt acacatatca ctatgatgct gattactctc gatgggattc aacacaacag
4321 agagccgtgt tggcagcagc tctagaaatc atggttaaat tctccccaga accacacttg
4381 gctcaggtag tcgcggagga ccttctttct cctagcgtgg tggacgtggg cgacttcaca
4441 atatcaatca acgagggtct tccctctggg gtgccctgca cctcccaatg gaactccatc
4501 gcccactggc ttctcactct ctgtgcactc tctgaagtca caaacctgtc ccctgatacc
4561 atacaggcta actccctctt ctctttttat ggtgatgatg aaattgttag cacagacata
4621 aaattggacc cagaaaaatt aacagcaaag ctcagagaat atgggttaaa accaacccgc
4681 cctgacaaaa ctgaaggacc ccttgtcatc tctgaagacc tgaatggcct aactttcctg
4741 cggagaaccg tgacccgcga cccagctggt tggtttggaa aactggagca gagttcaata
4801 ctcaggcaaa tgtactggac taggggtccc aaccatggag acccatctga aacaatgatc
4861 ccacactccc aaagacccat acaattgatg tccctactgg gggaggccgc tctccacggc
4921 ccagcatttt acagcaaaat cagcaaattg gtcattgcag agctaaaaga aggtggcatg
4981 gatttttacg tgcccagaca agagccaatg ttcagatgga tgagattctc agatctgagc
5041 acgtgggagg gcgatcgcaa tctggctccc agttttgtga atgaagatgg cgtcgagtga
5101 cgccaaccca tctgatgggt ccacagccaa ccttgtccca gaggtcaaca atgaggttat
5161 ggctttggag cccgtagttg gtgccgccat tgcggcacct gtagcgggcc aacaaaatgt
5221 aattgacccc tggattagaa ataattttgt acaagcccct ggtggagagt ttacagtatc
5281 ccctagaaac gctccaggtg aaatactatg gagcgcgccc ttaggccctg atttgaatcc
5341 ctacctttcc catttggcca gaatgtacaa tggttatgca ggtggttttg aagtgcaggt
5401 aatcctcgcg gggaacgcgt tcaccgccgg gaaaatcata tttgcagcag tcccaccaaa
5461 tttcccaact gaaggtttga gccccagcca ggtcactatg ttcccccaca taatagtaga
5521 tgttaggcaa ttggatcctg tgttgattcc cttacccgat gttaggaata atttctacca
5581 ttataatcaa tcaaatgatt ccaccatcaa attgatagca atgttgtata caccacttag
5641 ggctaataat gccggggacg atgtcttcac agtttcttgt cgagtcctca cgagaccatc
5701 ccccgatttt gattttatat ttttggtgcc acccacagtt gaatcaagaa ccaaaccatt
5761 ctctgtccca gttttaactg ttgaggagat gaccaattca aggttcccca ttcctttgga
5821 aaagttgttc acgggcccca gtagtgcctt tgtcgttcaa ccacaaaacg gcaggtgcac
5881 gactgatggc gtgctcctag gtaccaccca actgtctccc gtcaacatct gcaccttcag
5941 aggggatgtc acccatattt caggcagtca taactacaca atgaatttgg cctcccaaaa
6001 ttggaacagt tacgatccaa cagaagaaat cccagcccct ctaggaactc cagatttcgt
6061 gggaaagatt caaggtgtgc tcacccaaac cacaaggaca gatggctcga cccgcggcca
6121 caaagctaca gtgtacactg ggagcgccga cttctctcca aaactgggta gagttcaatt
6181 tgccactgac acagacaatg attttgaaac taaccaaaac acaaagttca ccccagtcgg
6241 tgttatccag gatggtggta cccaccaaaa tgaaccccaa caatgggagc tcccaagtta
6301 ctcaggcaga aacattcaca atgtgcacct ggcccccgct gtagccccca ctttcccggg
6361 cgagcagctc ctcttcttca gatctactat gcccggatgc agcgggtacc ccaacatgaa
6421 cttggattgt ctgctccccc aggagtgggt gcagtatttc taccaggagg cagccccagc
6481 acaatctgat gtggctctgc taagatttgt gaatccggat acaggtaggg ttttgtttga
6541 gtgtaagctt catagatcag gctatgtcac agtggctcac actggccaac atgatttggt
6601 tatccccccc aatggttatt ttagatttga ttcctgggtc aaccagttct acacacttgc
6661 ccccatggga aatggaacgg ggcgtagacg tgcattataa tggctggagc tatctttgct
6721 ggattggcat ctgacgtcct tagctctgga cttagttccc taatcaatgc tggggctggg
6781 gccatcaacc aaacaattga atttgaaaat aacagaaaac tgcaacaagc ttccttccag
6841 tttagtagca atctacaaca ggcttccttt caacatgaca aagagatgct ccatgcacaa
6901 attgaggcca ccaaaaagtt gcaacaggaa atgatgagag ttaaacaagc aatgctccta
6961 gagggtggat tctctgagac agatgcagcc cgcggggcaa tcaacgcccc catgacaaaa
7021 actttggact ggagcggaac aaggtactgg gctcccgatg ctaggactac aacatataat
7081 gcaggccgct tttccacccc ccaaccctcg ggggcaccac caggaagagc taatcttagg
7141 gctactgtcc ccgcccgggg ttcctctagc acatcttcta attcttctat tgctacttct
7201 gtgtattcaa atcaaaccac ctcaacgaga cttggttcta cagctggttc tggtaccagt
7261 gtctcgagcc tcccgtcaac tgcaaggact aggagttggg ttgaggatca aaataggaat
7321 ttgtcacctt tcatgagggg ggcccataac atctcgtttg tcaccccacc atctagcaga
7381 tcctctagcc aaggcacagt ctcaaccgtg cccaaagaag ttttggactc ctggactggc
7441 gctttcaaca cgcgcaggca gcctctcttt gctcacattc gtaagcgagg ggagtcacgg
7501 gtgtaatgtg aaaagaccaa attgattatc tttcttttct ttagtgtctt t
//