Typing tool
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Typing tool
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Complete norovirus genomes
| OQ702253 | GII.6 | |
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| GII.P7 |
ORF1: 1..5076
ORF2: 5057..6706
ORF3: 6706..7485
LOCUS OQ702253 7507 bp RNA linear VRL 02-APR-2023
DEFINITION Norovirus GII isolate 22GZ10387_GII.6-GII.P7 nonstructural
polyprotein (ORF1) gene, partial cds; and VP1 (ORF2) and VP2 (ORF3)
genes, complete cds.
ACCESSION OQ702253
VERSION OQ702253.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7507)
AUTHORS Su,W., Xie,H. and Zeng,Q.
TITLE Direct Submission
JOURNAL Submitted (28-MAR-2023) Derpartment of Virology, Guangzhou Center
for Disease Control and Prevention, Qide Road No. 1, Baiyun
District, Guangzhou, Guangdong 510440, China
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious Prime v. 23.0.4
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7507
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="22GZ10387_GII.6-GII.P7"
/isolation_source="anal swab"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="China: Guangzhou"
/collection_date="27-Sep-2022"
/note="genotype: GII.6[P7]"
gene <1..5076
/gene="ORF1"
CDS <1..5076
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="WEW53111.1"
/translation="DATTAFGSQNSVNDSFNTAPSKKEEVGAFSNIKVGFKKMLGAVP
KGTKAPSNDQHCPTVKIGTKTLTVPPEPPNGEDIVQFDAKSETVLGLPDLTTVQNEHE
NTPYSVPPLSEREHRPATEPLPGTILEMWDGEFYHYSIYVSGGKALGVHKPPAAISLA
TIELTPISLYWRPVYTPNYLVCPDTLKGLAGEKFPYTAFSNNCYNFCCWVLELNDTWL
SRRSISRTTGFFKPYQSWNRKPLPTVDDGKIKKVANAILCALGSLFSKPIKDLLGKLK
PLNLLHLLASCDWTFAGIVETVILMAELFNIFWTPPDVSNFISSLIGDFELQGPEDLA
VELVPVVMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMKWFFPKK
EEKAEMETLRAIEDAVLDMEAIGNNHLTTLLKDKDSLTAFMKTLDLEEEKARKLSTKS
SSPDIVGTINAILARIAAARSLLHKAKEEMFSRIRPVVVMISGRPGIGKTHMARHLAK
SIANTMSGDQRVGLVPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALTLQELADTCPV
TLNCDRIENKGKMFDSDVIIITTNLVNPAPLDYVNFEACSRRVDFLVYAESPEIEKVK
RDFPGQPDMWKDHFKPDFSHIKLTLAPQGGFDKNGNTPHGKGTMRSLTQGSLTARVAG
LVHERRDEFQLQGNDLQTYNFDTNRVSAFRKLAADNKYGIMETMRVGAALKNVKTLED
LKAALRDVKFNECEIIYRNSKYRISSNGKGSVSVDKVEGQTSQTANEVCSALLRLRQA
RARYYVSCFQDLIYTLMQVAGASFVVSRISKRFCWERWVKPTEAQETSESEKEVAQSS
WEIEPKDTEPEGKKGKNKKGRGKKHTAFSSKGLSDEEYDEFKRIREERNGKYSIEEYL
QDRDRYYEEVAVARATEEDFCEEEEAKIRQRIFRPTKKQRKEERGVLGLVTGSDIRKR
RPDDFQPKGKLWADDTRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSNLLITTTH
VLPKGIKELFGVEIKQIQIHKCGEFCRFRFPRPIRPDATGLVLEEGAPEGTVCSILVK
RPTGEMIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDCGCPYIYK
RGNDIVVAGVHTAAARGGNTVICATQGQDGEAVLEGNENLGTYCGAPILGPGKAPKLS
TKTKFWRSSPDALPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEPRGKPPRPA
ILEEAKKTVMNVLEQTIDPAKPWTYSQACASLDKTTSSGSPHHVKKNDHWNGESFTGP
LADQASKANLMYEQAKHVQPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGTMIRCAR
AFGGLMDSMKASCIALPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDSTQQRSIL
SAAMEVMVRFSAEPELAQVVAEDLLAPSQLDVGDFVISVQEGLPSGVPCTSQWNSIAH
WILTLSAMAEVSGLSPDVVQAHSCFSFYGDDEIVSTDINLDPMKLTQKLREYGLAPTR
PDKTEGPLVITEDLTGLTFLRRSIARDPAGWFGKLDQDSILRQLYWTRGPNHENPYES
MVPHSQRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEAMFRWMRF
SDLSTWEGDRNLAPEGVNEDGVD"
mat_peptide <1..984
/gene="ORF1"
/product="p48"
mat_peptide 985..2082
/gene="ORF1"
/product="NTPase"
mat_peptide 2083..2601
/gene="ORF1"
/product="p22"
mat_peptide 2602..3000
/gene="ORF1"
/product="VPg"
mat_peptide 3001..3543
/gene="ORF1"
/product="Pro"
mat_peptide 3544..5073
/gene="ORF1"
/product="RdRp"
gene 5057..6706
/gene="ORF2"
CDS 5057..6706
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="WEW53112.1"
/translation="MKMASTDAAPSNDGAANLVPEANNEVMALEPVVGASIAAPVVGQ
QNIIDPWIRENFVQAPQGEFTVSPRNSPGEMLLNLELGPELNPYLSHLSRMYNGYAGG
MQVQVVLAGNAFTAGKIIFAAVPPHFPVENISAAQITMCPHVIVDVRQLEPVLLPLPD
IRNRFFHYNQEDTPRMRLVAMLYTPLRANSGEDVFTVSCRVLTRPAPDFEFTFLVPPT
VESKTKPFTLPILTLGELSNSRFPAPIDMLYTDPNEGVVVQPQNGRCTLDGTLQGTTQ
LVPTQICAFRGKLIGQTSRSPDSDSTDSAPRRRDHPLHVQLENLDGTQYDPTDEVPAT
LGAVDFKGTIFGVASQRDTSGSQVGATRAHEVHINTTDPRYTPKLGSILMYSESLDFE
TGQPVRFTPIGMGENDWHQWELPDYSGRLTLNMNLAPAVAPAFPGERILFFRSIVPSA
GGYGSGQIDCLIPQEWVQHFYQEAAPSQSAVALIRYVNPDTGRNIFEAKLHREGFITV
ANSGNNPIVVPPNGYFRFEAWVNQFYTLTPMGTGQGRRRNQ"
gene 6706..7485
/gene="ORF3"
CDS 6706..7485
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="WEW53113.1"
/translation="MASAFLAGLAGDVITNGVGSLINAGANAINQKVEYDFNKQLQLA
SFKHDKEMLQSQVSATKQLQQEMMNIRQGVLTAGGFSPADAARGAVNAPMTKILDWNG
TRYWAPNSMKTTSYSGQFSSSPVHRSSAPSQLVASSKGKLQNDSASVYSSPSSVSSQS
THSTVLSTGTRSSRPTTTSTATPTLSRTSDWVRGQNERLSPFMDGALQTAFVTPPSSK
ASSNGTVSTVPKAVLDSWTPMFNTHRQPLFAHLRRRGESQV"
ORIGIN
1 gacgctacca ctgcctttgg cagtcaaaac tctgtcaatg acagttttaa caccgcccct
61 tctaagaaag aagaggttgg tgcattctcc aacatcaaag ttggatttaa gaaaatgctg
121 ggtgccgttc ccaaggggac caaagcaccc agcaatgatc agcactgtcc cacagttaag
181 atcgggacca aaacattaac agttccccct gagcccccaa atggtgaaga catcgtgcag
241 tttgatgcga agtcagaaac tgtgcttggg ctaccagact taacaacggt gcaaaatgaa
301 cacgagaaca caccatactc agtcccccca ttgagtgaaa gggaacacag accagccact
361 gagccgctcc ctggcacaat actggagatg tgggatggtg aattctacca ctactccata
421 tacgtcagcg gtggcaaagc cctaggggtt cataagcccc ctgcggcaat tagcctcgcg
481 acgatagagc tcacacccat atctctttac tggaggcccg tttacacccc caactacctg
541 gtctgcccgg acacgttgaa aggcctcgct ggtgagaagt tcccctacac ggccttcagc
601 aacaactgtt acaacttctg ttgctgggtg cttgaactca atgacacgtg gcttagcagg
661 agaagcatct ccaggaccac cggcttcttc aaaccatacc agtcttggaa caggaaaccc
721 ctcccaaccg ttgatgatgg aaagatcaaa aaggtggcca acgcaatcct ctgtgcactt
781 ggatcactgt tttcaaaacc aatcaaagac ctgttaggca aacttaaacc attgaacttg
841 ttgcacttgc tcgcgtcatg tgattggacg tttgcgggca tagtggagac agttatccta
901 atggcagaac ttttcaacat cttttggaca ccgccagacg tttccaactt catatcctcc
961 ctgataggtg attttgaatt gcaagggcct gaggacctgg ccgtggagct cgtccccgtg
1021 gtcatgggtg gcataggaat ggttctcggc tttactgctg agaagatagg ccgcatgctg
1081 tcgtccgctg catcaacact gcgggcatgt aaagaccttg ggaattatgc ccttgacata
1141 ctaaaactgg ttatgaaatg gttcttccca aagaaggaag agaaagccga gatggaaacc
1201 ttaagggcga ttgaggatgc cgtcctggac atggaggcta taggaaacaa tcatctcaca
1261 accctcctca aagataagga tagcctcacg gccttcatga agaccctgga cctagaagag
1321 gagaaggcaa ggaagctgtc caccaaatca tcctcgccag acatcgtcgg tactatcaat
1381 gccatactgg ccagaatagc tgctgccaga tccctcctgc acaaggctaa agaagaaatg
1441 tttagtagga tcagacctgt ggttgttatg atctcgggta gacctggtat tggcaaaacc
1501 cacatggcaa gacacttggc taagagcatc gccaacacca tgagtggcga ccagagagtc
1561 gggctcgttc cgcgcaacgg ggtcgatcac tgggacgcct acagggggga gagggtggtc
1621 ttatgggatg attatggcat gggaaaccct gtcaaagatg ctctaacact gcaagagttg
1681 gccgacacct gcccagtaac tctaaactgt gataggattg agaacaaggg gaagatgttc
1741 gacagtgatg tcatcataat cacgaccaac ctagtcaacc cagcacccct cgattatgta
1801 aacttcgagg cgtgctccag aagggttgac tttctggtct atgcagagtc accagaaatt
1861 gagaaggtta agagagattt ccccggccag cctgacatgt ggaaggacca ctttaagcca
1921 gacttctccc atataaaact gactctagcc ccccagggtg gatttgacaa aaatggtaac
1981 accccgcatg gcaagggcac catgcggtcc ctaacccagg ggtccctgac tgcaagggtt
2041 gcaggccttg ttcatgagag gagagatgag tttcagctcc aggggaacga ccttcaaaca
2101 tacaactttg acaccaacag ggtctccgca tttaggaagc tggccgcaga taacaagtat
2161 ggaatcatgg aaacaatgag agtaggtgcg gcgcttaaga atgtcaagac cttggaagat
2221 ctgaaagctg ccctgaggga tgtgaagttc aatgagtgtg agataattta caggaactcc
2281 aaatatcgaa tctcctccaa cggtaaaggt tctgtctctg ttgacaaagt tgagggccaa
2341 acgtcccaga ctgcgaacga ggtgtgttca gcactcctta ggctcaggca ggcaagggcc
2401 agatactatg tcagctgctt ccaagatctc atctacactc taatgcaggt tgccggagcg
2461 tcattcgttg tcagcagaat ttctaagagg ttctgttggg agaggtgggt caaaccaacc
2521 gaggcccagg aaacgagtga atccgaaaag gaagtagcac aaagtagctg ggagattgaa
2581 cccaaggaca cagaaccaga aggtaagaag ggtaagaaca agaaaggaag aggcaagaaa
2641 cacacagctt tctccagcaa aggcctgagt gatgaggagt atgacgagtt caagagaatc
2701 agggaagaaa ggaacgggaa atactccatt gaagaatacc tgcaagaccg ggatcgctac
2761 tatgaggaag tggcggttgc ccgggcgaca gaggaggact tctgtgaaga ggaggaggcc
2821 aagataagac aaagaatctt ccgccccaca aagaaacaga ggaaggaaga aaggggggtg
2881 cttggcttgg tcactggctc agacatcagg aagaggagac cagatgattt ccaaccaaag
2941 ggcaaactgt gggcagacga taccagaagt gtggactaca acgagagact tgatttcgag
3001 gctcccccga gtgtctggtc gagaatagtc ccattgggca ctggctgggg cttttgggtc
3061 tcatccaacc tcctgatcac aacaacacat gtcctgccta aggggattaa ggaacttttt
3121 ggggttgaaa tcaaacagat ccaaattcat aagtgtggag agttttgcag gttcagattc
3181 ccaagaccaa tcaggccaga tgccacaggg ctcgtgctgg aggaaggtgc tccagaaggc
3241 actgtctgct ccatactcgt aaagagacct acaggtgaga tgatccctct ggcagtgagg
3301 atgggcacgc atgcatccat gaagatacag ggtaggaccg tcggtggcca aatgggaatg
3361 ctcctcacag gggctaacgc gaagaacatg gatcttggca ccggccctgg tgactgcggt
3421 tgcccttata tctacaaacg cggcaatgac atagttgtcg cgggtgtcca caccgcagca
3481 gcccggggag gcaataccgt catatgtgcc actcaagggc aagatgggga ggcagttctt
3541 gagggaaatg agaaccttgg cacttactgc ggtgccccaa ttttgggtcc gggcaaggcg
3601 cccaaactca gcacgaagac caaattctgg cgttcatcac cagacgcttt gccgccaggc
3661 acttatgagc ctgcctacct aggaggcaag gaccccagag tggagaaagg accatccctg
3721 cagcaagtca tgagggatca gttaaaacct ttcacagaac ccagaggcaa accacctaga
3781 cctgcaatct tagaagaagc caaaaagaca gtgatgaatg ttctagaaca aaccatcgac
3841 cctgccaagc catggaccta ttcccaagca tgtgcctcac tggacaagac cacttctagt
3901 ggtagccccc accatgtcaa gaaaaatgac cattggaatg gagaatcctt caccggcccc
3961 cttgcagacc aagcatccaa agccaatctc atgtatgagc aggccaaaca tgtgcagccc
4021 gtgtacacgg ccgctctcaa agatgagctt gtcaagactg acaaaatcta caaaaagata
4081 aagaagaggc tcttatgggg gtcggatctt ggtacgatga tcaggtgcgc cagggccttt
4141 ggcggtctca tggatagcat gaaggcaagc tgtatagccc tcccatgcag ggtaggaatg
4201 aacatgaacg aagatggtcc catcatattt gacaagcact ctaagtacag gtatcactat
4261 gatgctgact attccaggtg ggattcaacc cagcaaagga gcattctctc ggccgctatg
4321 gaagtgatgg tgcggttttc tgccgaacca gagctggcac aggtggttgc agaggacctt
4381 ctggcaccca gccaactaga tgttggcgat tttgtcatct cagtccagga gggtctgcca
4441 tcaggggtcc catgcacatc acagtggaat tcaatagcac attggatcct aaccctgagt
4501 gcaatggcag aagtgtcagg tctctcacca gatgtagttc aagcccactc ctgtttctca
4561 ttttacggtg acgatgagat cgtcagcact gacataaacc ttgatcccat gaagttgaca
4621 cagaaactca gggaatatgg tctggccccc acccggcctg ataaaactga aggccccctc
4681 gtaataactg aagacctcac cggcctaacg ttccttcgta ggtcgattgc acgagaccca
4741 gctgggtggt ttggaaaatt ggaccaggac tcaatcctca ggcagttata ttggacaaga
4801 ggccccaatc atgagaatcc atatgagagc atggtccctc actcccaacg ggccacacaa
4861 ctcatggccc ttctcggtga agcctcacta catggccccc agttctacaa gaaagttagc
4921 aagatggtca tcaatgaaat caaaagtggt ggtctggaat tttatgtgcc cagacaagag
4981 gccatgttca ggtggatgag attctctgac ctcagcacat gggagggcga tcgcaatctt
5041 gctcccgagg gtgtgaatga agatggcgtc gactgacgct gctccatcga atgatggtgc
5101 tgccaacctc gtaccagagg ccaacaatga ggttatggca cttgaaccgg tggtgggagc
5161 ctcaatcgcg gctcctgtcg tcggccaaca aaacataatt gacccctgga ttagagaaaa
5221 ttttgtccaa gcaccacagg gcgagttcac cgtctcaccg agaaactcgc ctggtgagat
5281 gctattaaat cttgaattag gcccagaact taacccttac ctaagtcatt tgtcccgcat
5341 gtacaacggg tatgctggtg gcatgcaggt tcaggtggtc ctggctggga atgcgttcac
5401 agctgggaaa atcatctttg ccgccgtgcc accacatttt cccgtagaaa acatcagtgc
5461 agcccaaata actatgtgcc cccatgtaat tgttgatgtg aggcaacttg aaccagtact
5521 tttgcccctc cctgacataa ggaacaggtt cttccattac aatcaggaag acaccccccg
5581 gatgaggctt gtggcaatgc tttatactcc cctgagggct aattctggtg aagatgtgtt
5641 tactgtctct tgtagggttt taacccgtcc tgcccctgat tttgaattca ctttcttggt
5701 gccaccaacc gttgaatcaa agactaaacc ttttacacta cccatattaa ctcttggtga
5761 gctatccaac tctagattcc cagccccgat agacatgttg tacactgacc caaatgaggg
5821 ggttgtggtc caaccacaaa atggtaggtg cactcttgat ggcactctgc aaggcaccac
5881 acaactggtc cccacccaaa tttgtgcttt caggggcaaa ctaattggcc agacatcaag
5941 gtctccagac tcagactcaa ctgactcagc ccctcggaga agggatcacc cactccatgt
6001 gcaattagag aatcttgatg gcacgcagta cgacccaact gatgaagtgc cagcaaccct
6061 tggtgccgtt gacttcaagg ggaccatttt tggagtggcc agtcagagag acacgtcagg
6121 gagccaagtg ggggcaaccc gagcccatga ggtgcacatt aacacgaccg atcccaggta
6181 tacaccaaaa ctggggtcca tcctcatgta ctcagagtcg ctagactttg agactggaca
6241 gccggtccgc ttcacaccta taggaatggg tgagaacgat tggcaccagt gggagctgcc
6301 tgactactct ggacgcctga ccctgaacat gaatcttgcc ccagctgttg ctcctgcttt
6361 tcccggtgag aggattcttt tcttcaggtc aatagtccca tctgctggtg gctatgggtc
6421 tggacagata gattgcctca taccacagga gtgggttcag catttctacc aggaagctgc
6481 accgtcccaa tctgccgtgg cactcatcag gtatgtcaat cctgacacag gcagaaacat
6541 ctttgaggct aagctgcata gggaaggttt catcaccgtg gcaaattctg gtaacaaccc
6601 cattgttgtc ccccctaatg ggtatttcag gtttgaagct tgggtgaacc aattttatac
6661 tttgaccccc atgggaactg gtcaggggcg caggaggaat caataatggc tagtgctttt
6721 cttgcaggtc ttgctggcga cgtcataaca aatggcgttg gatctttaat aaatgctgga
6781 gctaatgcaa ttaatcagaa agttgaatat gattttaata aacagcttca attggcatca
6841 tttaaacatg ataaagagat gttgcaatca caagtttcag caaccaagca gttgcagcag
6901 gagatgatga acataaggca gggggtgttg accgctggcg gcttctcccc cgcggacgct
6961 gctagagggg ccgttaacgc cccaatgaca aagattctgg attggaatgg caccaggtat
7021 tgggcaccaa acagcatgaa aactacaagc tactcaggac agttctctag cagccctgtt
7081 catagatcct ctgctccttc ccagcttgtt gcctcatcaa agggtaaatt gcaaaatgat
7141 tctgctagtg tatatagctc tccttcctct gtttcttcac aatcaaccca ttcaacagtg
7201 ctgtcaacag gaactagatc atccaggccc actaccacat ccacagcaac ccccaccttg
7261 tctaggacca gcgactgggt taggggacag aatgagaggc tcagcccgtt tatggacggt
7321 gctctccaaa ctgcctttgt cacacctcca tcgagcaaag cttcttcaaa tggcacggtc
7381 tcaaccgttc ccaaagctgt tttggactcc tggactccta tgtttaacac acataggcag
7441 cctctcttcg cccacctacg caggcgaggg gagtcacaag tttagtgaaa agagtgatta
7501 ggttttc
//