Typing tool
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Typing tool
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Complete norovirus genomes
| OQ451922 | GII.4 Sydney | |
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| GII.P31 |
ORF1: 1..4435
ORF2: 4416..6038
ORF3: 6038..6844
LOCUS OQ451922 6844 bp RNA linear VRL 22-FEB-2023
DEFINITION Norovirus GII isolate Hu/CHN/2021/GII.P31-GII.4/SJZ8608
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION OQ451922
VERSION OQ451922.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 6844)
AUTHORS Chen,L.-N., Wang,S.-J., Wang,S.-M., Fu,X.-L., Zheng,W.-J.,
Hao,Z.-Y., Zhou,H.-S., Zhang,X.-J., Zhao,Y.-L., Qiu,C.,
Seidlein,Lv., Qiu,T.-Y. and Wang,X.-Y.
TITLE Molecular epidemiology analysis of symptomatic and asymptomatic
norovirus infections in Chinese infants
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 6844)
AUTHORS Chen,L.-N., Wang,S.-J., Wang,S.-M., Fu,X.-L., Zheng,W.-J.,
Hao,Z.-Y., Zhou,H.-S., Zhang,X.-J., Zhao,Y.-L., Qiu,C.,
Seidlein,Lv., Qiu,T.-Y. and Wang,X.-Y.
TITLE Direct Submission
JOURNAL Submitted (17-FEB-2023) Institutes of Biomedical Sciences, Fudan
University, Dongling Road, Shanghai, Shanghai 200032, China
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..6844
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/CHN/2021/GII.P31-GII.4/SJZ8608"
/isolation_source="fecal sample"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="China"
/collection_date="Feb-2022"
/note="genotype: GII.4"
gene <1..4435
/gene="ORF1"
CDS <1..4435
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="WDE42342.1"
/translation="RMIHRTTGFFGPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLF
TRPIKDIIGKLKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLL
GDYELQGPEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEI
LKLVMKWFFPKKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLTTYMRTLDL
EEEKARKLSTKSASPDIVGTINSLLARIAAARSLVHRAKEELSSRPRPVVVMISGRPG
IGKTHLARELAKKIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDA
LRLQELADTCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFL
VYAEAPEVEKAKRDFPGQPDMWKNAFSPDFSHIKLSLAPQGGFDKNGNTPHGKGVMKT
LTTGSLIARASGLLHERLDEYELQGPALTTFNFDRNKILAFRQLAAENKYGLMDTMRV
GKQLKDVKTMSDLKQALKNIAIKKCQIVYNGGTYTLEADGKGSVKVDKVQSATVQTNN
ELAGALHHLRCARIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVED
TEEMANKDGCLKPKDDEEFVVSSDDIKTEGKKGKNKSGRRQKHTAFSSKGLSDEEYDE
YKRIREERNGKYSIEEYLQDRDRYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQR
KEERASLGLVTGSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLNFEAPPSIWSRIVNF
GSGWGFWVSPSLFITSTHVIPQGAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTG
MILEEGAPEGTVATLPTERPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAK
SMDLGTTPGDCGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDSK
GTYCGAPILGPGSAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVM
RDQLKPFTEPRGKPPRPNVLEAAKKTIINVLEQTIDPPQKWSFAQACASLDKTTSSGH
PHHMRKNDCWNGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKVYGKV
KKRLLWGSDLATMVRCARAFGGLMDELKAHCVTLPVRVGINMNEDGPIIFEKHSRYRY
HYDADYSRWDSTQQRDVLAAALEIMVKFSPEPHLAQIVAEDLLSPSVMDVGDFQISIS
EGLPSGVPCTSQWNSIAHWLLTLRVLSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKL
DPERLTAKLKEYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQGSI
LRQMYWTRGPNHEDPFETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEG
GMDFYVPRQEPMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..325
/gene="ORF1"
/product="p48"
mat_peptide 326..1423
/gene="ORF1"
/product="NTPase"
mat_peptide 1424..1960
/gene="ORF1"
/product="p22"
mat_peptide 1961..2359
/gene="ORF1"
/product="VPg"
mat_peptide 2360..2902
/gene="ORF1"
/product="Pro"
mat_peptide 2903..4432
/gene="ORF1"
/product="RdRp"
gene 4416..6038
/gene="ORF2"
CDS 4416..6038
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="WDE42343.1"
/translation="MKMASSDVNPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSHNYTMNLASQNWSNYDPTEEIPAPLGTPDFVGKIQGML
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTNNDFEANQNTKFTPVGVIQDG
GTTHRNEPQQWVLPSYSGRNTPNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGAGRRRAL"
gene 6038..6844
/gene="ORF3"
CDS 6038..6844
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="WDE42344.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKRLQRETMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRANFRDAVPARGSSSKSS
NSSTATSVYSNQTTSTRLGSTAGSGTSVSSFPSTARTRSWVEDQSRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 aagaatgatt catagaacaa caggcttctt tgggccgtac caggattgga acaggaaacc
61 cctccccact atggatgact ccaaattaaa gaaggtagcc aacatattct tgtgcacttt
121 gtcttcacta ttcaccaggc ccattaagga cataataggg aagttgaaac ctctcaacat
181 ccttaatatt ctggctacat gtgattggac cttcgcaggc atagtggaat ccttaatact
241 cttggcagaa ctctttggag ttttctggac acccccagat gtgtctgcga tgatcgcccc
301 cttgcttggt gattatgaac tgcaaggacc cgaggacctt gcagtggaac tggtcccagt
361 agtgatgggg gggataggtt tggtgctagg atttaccaaa gagaagatcg gtaaaatgtt
421 gtcatccgct gcatccactt taagagcttg caaagacctt ggtgcatacg gactggaaat
481 cttaaaactg gtcatgaagt ggttcttccc aaagaaagag gaagcaaatg aactggccat
541 ggtgagatcc atcgaggatg cagtactaga cctcgaggca attgaaaaca accacatgac
601 caccctgctc aaagacaaag acagcttgac aacctacatg agaacccttg accttgagga
661 ggagaaagcc agaaaactct caaccaaatc tgcttcaccc gatattgtgg gcacaatcaa
721 ctctcttctg gcaagaatcg ctgctgcacg ctccctagtg catcgggcga aagaagagct
781 ctccagcagg ccgagacctg tcgttgtaat gatatcggga agaccaggga tagggaaaac
841 tcaccttgcc agggagctgg ccaagaagat cgcggcctcc ctcacagggg accagcgtgt
901 gggccttatc ccacgcaatg gtgtcgacca ctgggacgca tacaagggcg aaagggttgt
961 cctatgggac gactatggaa tgagcaaccc catccatgat gcccttaggt tgcaggagct
1021 tgctgacact tgccccctca cgctaaattg tgacagaatt gagaacaaag gaaaagtctt
1081 tgacagtgat gccataatta tcaccaccaa cctggccaac ccagcaccac tggattatgt
1141 caactttgaa gcgtgttcga gacgcattga tttcctcgtg tacgcagaag cccctgaggt
1201 ggagaaggca aagcgcgact tcccaggtca acctgacatg tggaaaaacg cttttagtcc
1261 tgacttctca cacataaaac tgtcattggc tccacagggt ggttttgaca agaacggaaa
1321 caccccgcat ggaaaagggg tcatgaagac cctcaccact ggctccctca tcgcccgagc
1381 atcagggttg ctccatgaga ggctagatga atatgaattg caaggcccag ccctcaccac
1441 tttcaacttt gaccgcaaca agatactcgc ttttaggcag cttgctgctg aaaacaagta
1501 tgggctgatg gacacaatga gagttggaaa acagctcaag gatgtcaaga ctatgtcaga
1561 cctcaaacaa gcactcaaga acatcgcgat caagaagtgc cagatagtgt acaatggtgg
1621 cacctacaca cttgaggctg atggcaaggg cagtgtgaaa gttgataaag tgcaaagtgc
1681 cactgtgcag accaacaatg aactagccgg tgccctacac cacctaagat gcgctagaat
1741 cagatactat gttaagtgcg tccaggaggc actgtattcc atcatccaaa tcgctggggc
1801 tgcattcgtc accacgcgca tcgctaagcg catgaatata cagaatctct ggtccaagcc
1861 acaggtggaa gacacagaag agatggccaa caaagatggt tgcctaaaac ccaaagatga
1921 tgaagagttt gtcgtttcat ccgacgacat caaaactgag ggcaagaaag ggaagaacaa
1981 gtccggccgt cgtcagaagc acacagcctt ttcaagtaaa gggctcagtg atgaggagta
2041 cgatgagtac aagagaatca gagaagaaag gaatggtaag tactccatag aagagtacct
2101 tcaggacaga gacaggtact acgaggaggt ggccattgcc agggcaaccg aagaggactt
2161 ctgtgaagaa gaagaggcca aaatccggca gaggattttc agaccaacaa ggaaacaacg
2221 caaagaagag agggcttctc tcggcttggt cacaggttct gaaatcagga agagaaaccc
2281 agaagacttc aaacccaagg gaaagctgtg ggctgatgac gacagaagtg ttgactacaa
2341 tgagaaactc aactttgagg ccccaccaag catctggtcg cggatagtca actttggttc
2401 aggctggggc ttctgggtct cccccagtct gtttataaca tcaacccatg tcatacccca
2461 aggtgcaaag gagttcttcg gagtccctat caagcaaatc cagatacaca agtcaggtga
2521 attctgccga ttgagattcc caaagccaat cagaaccgat gtgacgggca tgattctaga
2581 agaaggtgcg cccgagggga ccgtggccac actccccact gagagaccaa ctggagagct
2641 catgcctctg gcagccagaa tggggaccca tgcaaccatg aaaattcagg ggcgcacagt
2701 tggagggcaa atgggtatgc tcctgacagg atctaacgcc aagagtatgg acctaggcac
2761 aacaccaggt gactgcggct gcccctacat ctacaagagg gggaatgact acgtggtcat
2821 aggggtccat acggctgctg ctcgtggagg aaacactgtc atatgtgcca cccagggaag
2881 tgagggagag gccacacttg aaggaggtga cagtaaaggg acatactgtg gcgcgccaat
2941 cttgggacca gggagcgctc cgaagctcag cactaagact aagttttgga ggtcatccac
3001 aacaccactc ccacctggca cctacgaacc agcctacctc ggtggcaaag accctagagt
3061 caaaggtggc ccttcattgc aacaagttat gagggaccag ctgaagccat tcacagaacc
3121 cagaggcaaa ccaccaagac caaatgtgtt ggaagctgcc aagaaaacca tcatcaatgt
3181 ccttgagcaa acaattgatc caccccaaaa atggtcattt gcgcaagctt gcgcatccct
3241 tgacaaaacc acctccagcg gccacccgca ccacatgcgg aaaaacgact gttggaatgg
3301 ggagtccttc acaggaaagt tggctgacca agcctccaag gccaacctaa tgtttgaaga
3361 gggaaagaac atgactccag tctatacagg tgcacttaaa gatgagttgg taaagaccga
3421 taaagtgtat ggtaaggtca agaagaggct tctatggggt tcagatctgg cgaccatggt
3481 acggtgcgcc cgagcttttg gaggcctcat ggatgaactc aaggcacact gtgtcacact
3541 ccctgtcaga gttggtataa acatgaatga ggatggcccc atcatcttcg agaagcactc
3601 cagatataga tatcattatg atgctgacta ttcccggtgg gactcaacac aacaaaggga
3661 tgtgctggca gcagcactag agatcatggt taagttctct ccagaaccac acctggccca
3721 gatagttgca gaagacctcc tttcccctag cgtgatggat gtgggtgact ttcaaatatc
3781 aataagtgag ggtctcccct ctggggtgcc ttgcacctcc cagtggaatt ccatcgccca
3841 ctggctcctc actctccgag tgctctctga agtcacggac ctgtcccctg atattattca
3901 ggccaactcc cttttctcct tctatggtga tgatgagatt gtaagcacag atataaagtt
3961 ggacccagag aggctaacag caaagctcaa ggagtacggg ctaaaaccaa cccgccccga
4021 caaaactgaa ggaccccttg tcatctctga agacctggat ggtctgacat tcctccggag
4081 aactgtgacc cgtgatccag ctggctggtt tggaaaattg gaacaaggtt caattcttag
4141 gcaaatgtac tggaccaggg gccccaacca tgaagaccca tttgaaacaa tgataccaca
4201 ctcccaaaga cccatacaat tgatgtcctt gctgggcgag gctgcactcc acggcccggc
4261 attctacagc aaaattagca aattagtcat tgcagagttg aaggaaggtg gcatggattt
4321 ttacgtgccc agacaagagc caatgttcag atggatgaga ttctcagatc tgagcacgtg
4381 ggagggcgat cgcaatctgg ctcccagttt tgtgaatgaa gatggcgtcg agtgacgtca
4441 acccatctga tgggtccgca gccaacctcg tcccagaggt caacaatgag gttatggctc
4501 tggagcccgt tgttggtgcc gccattgcgg cacctgtagc gggccaacaa aatgtaattg
4561 acccctggat tagaaacaat tttgtacaag cccctggtgg agagttcaca gtatccccta
4621 gaaacgctcc aggtgaaata ctatggagcg cgcccttggg ccctgatctg aatccctact
4681 tgtctcattt ggccagaatg tacaatggtt atgcaggtgg ttttgaagtg caggtaatcc
4741 tcgcggggaa cgcgttcacc gccgggaagg tcatatttgc agcagtccca ccaaatttcc
4801 caactgaagg cttgagcccc agccaggtca ctatgttccc ccatatagta gtagatgtta
4861 ggcaactaga acctgtgttg attcccttac ccgatgttag gaataatttc tatcactaca
4921 atcaatcaaa tgaccccact attaagttga tagcaatgtt gtatacacca cttagggcta
4981 ataatgctgg ggatgatgtc ttcacagttt cttgtcgagt tctcacgaga ccatcccccg
5041 attttgactt catatttcta gtgccaccca cagttgagtc aaggactaaa ccattctctg
5101 tcccagtttt gactgttgag gagatgacca attcaagatt ccccattccc ttggaaaagt
5161 tgttcacggg tcccagcagt gccttcgttg tccaaccaca aaatggtagg tgcacgactg
5221 atggcgtgct cctaggcacc acccaactgt ctcctgtcaa catctgcacc ttcagaggag
5281 atgtcaccca tatcacaggt agtcataact acacaatgaa tttggcttct caaaattgga
5341 gcaactacga cccaacagaa gaaatcccag cccctctagg gactccagac tttgtgggga
5401 agatacaagg catgctcacc caaaccacaa ggacagatgg ctcaacacgc ggccacaaag
5461 ccacagtgta cactgggagc gccgactttg ctccaaaact gggtagagtc caatttgaaa
5521 ctgacacaaa caatgatttt gaggctaacc aaaacacaaa gttcacccca gttggtgtca
5581 tccaagatgg tggcaccact catcgaaatg aaccccaaca gtgggtgctc ccaagttact
5641 caggcaggaa cactcctaat gtgcatctgg cccccgctgt ggcccccact tttccgggtg
5701 agcaactcct tttctttaga tccaccatgc ccggttgcag cgggtatccc aacatggatt
5761 tggattgtct gctcccccag gaatgggtgc agtacttcta ccaggaggca gccccagcac
5821 aatctgatgt ggctctgcta agatttgtga atccagacac aggtagggtt ttgttcgaat
5881 gtaagcttca taaatcaggc tatgtcacag tggctcacac tggccaacat gatttggtta
5941 tcccccccaa tggttatttt aggtttgatt cctgggtcaa ccagttttac acacttgccc
6001 ccatgggaaa tggagcgggg cgtagacgtg cactataatg gctggagctt tctttgctgg
6061 attggcatct gatgtccttg gctctggact tggttccctt atcaatgctg gggctggggc
6121 catcaaccaa aaagttgagt ttgaaaataa tagaaaattg cagcaagcat ccttccaatt
6181 tagcagcaat ctacaacagg cttcctttca acatgacaaa gagatgctcc aagcacaaat
6241 tgaggctacc aaaaggttac aacgggaaac gatgaaagtt aagcaggcaa tgctcctaga
6301 gggtgggttc tctgagacag atgcagcccg cggggcaatc aacgccccta tgacaaaagc
6361 cttggactgg agcgggacaa ggtactgggc tcctgatgct aggactacaa catacaatgc
6421 aggccgcttt tccacccccc aaccatcagg ggcgttgcca ggaagagcta attttaggga
6481 tgctgtccct gctcggggtt cttctagtaa gtcttctaat tcttctactg ctacttctgt
6541 gtattcaaat caaacaactt caacgagact tggttctaca gctggttctg gtaccagtgt
6601 ctcgagcttc ccgtcaactg caaggactag gagctgggtt gaggaccaaa gtaggaattt
6661 gtcacctttc atgagggggg cccacaacat atcgtttgtc accccaccat ctagcaggtc
6721 ctctagccaa ggcacagtct caaccgtgcc taaagagatt ttggactcct ggactggcgc
6781 tttcaacacg cgcaggcagc cactcttcgc tcacattcgt aagcgagggg agtcacgggt
6841 gtaa
//