Typing tool
|
|
|
|
|
|
Typing tool
|
Complete norovirus genomes
| OQ451916 | GII.4 Sydney | |
|
|---|---|---|---|
| GII.P31 |
ORF1: 1..4435
ORF2: 4416..6038
ORF3: 6038..6844
LOCUS OQ451916 6881 bp RNA linear VRL 22-FEB-2023
DEFINITION Norovirus GII isolate Hu/CHN/2021/GII.P31-GII.4/SJZ8032
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION OQ451916
VERSION OQ451916.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 6881)
AUTHORS Chen,L.-N., Wang,S.-J., Wang,S.-M., Fu,X.-L., Zheng,W.-J.,
Hao,Z.-Y., Zhou,H.-S., Zhang,X.-J., Zhao,Y.-L., Qiu,C.,
Seidlein,Lv., Qiu,T.-Y. and Wang,X.-Y.
TITLE Molecular epidemiology analysis of symptomatic and asymptomatic
norovirus infections in Chinese infants
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 6881)
AUTHORS Chen,L.-N., Wang,S.-J., Wang,S.-M., Fu,X.-L., Zheng,W.-J.,
Hao,Z.-Y., Zhou,H.-S., Zhang,X.-J., Zhao,Y.-L., Qiu,C.,
Seidlein,Lv., Qiu,T.-Y. and Wang,X.-Y.
TITLE Direct Submission
JOURNAL Submitted (17-FEB-2023) Institutes of Biomedical Sciences, Fudan
University, Dongling Road, Shanghai, Shanghai 200032, China
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..6881
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/CHN/2021/GII.P31-GII.4/SJZ8032"
/isolation_source="fecal sample"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="China"
/collection_date="Feb-2022"
/note="genotype: GII.4"
gene <1..4435
/gene="ORF1"
CDS <1..4435
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="WDE42324.1"
/translation="RMIQRTTGFFGPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLF
TRPIKDIIGKLKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLL
GDYELQGPEDLAVELVPIVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEI
LKLVMKWFFPKKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDL
EEEKARKLSTKSASPDIVGTINSLLARIAAARSLVHRAKEELSSRPRPVVVMISGRPG
IGKTHLARELAKKIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDA
LRLQELADTCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFL
VYAEAPEVEKAKRDFPGQPDMWKNAFSPDFSHIKLSLAPQGGFDKNRYTPHGKGVMKT
LTTGSLIARASGLLHERLDEYELQGPALTTFNFDRNKILAFRQLAAENKYGLMDTMRV
GKQLKDVKTMSDLKQALKNIAIKKCQIVYNGGTYTLEADGKGSVKVDKVQSATVQTNN
ELAGALHHLRCARIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVED
TEEVANKDGCLKPKDDEEFVVSSDDIKTEGKKGKNKSGRGQKHTAFSSKGLSDEEYDE
YKRIREERNGKYSIEEYLQDRDRYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQR
KEERASLGLVTGSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLNFEAPPSIWSRIVNF
GSGWGFWVSPSLFITSTHVIPQGAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTG
MILEEGAPEGTVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAK
SMDLGTTPGDCGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGNEGEATLEGGDSK
GTYCGAPILGPGSAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVM
RDQLKPFTEPRGKPPRPNVLEAAKKTIINVLEQTIDPPQKWSFAQACASLDKTTSSGH
PHHMRKNDCWNGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKVYGKV
KKRLLWGSDLATMVRCARAFGGLMDELKAHCVTLPVRVGINMNEDGPIIFEKHSRYRY
HYDADYSRWDSTQQRDVLAAALEIMVKFSPEPHLAQIVAEDLLSPSVMDVGDFQISIS
EGLPSGVPCTSQWNSIAHWLLTLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKL
DPERLTAKLKEYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSI
LRQMYWTTGPNHEDPFETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEG
GMDFYVPRQEPMFIWMRFSDLTTWEGDRNLAASFVNEDGVE"
mat_peptide <1..325
/gene="ORF1"
/product="p48"
mat_peptide 326..1423
/gene="ORF1"
/product="NTPase"
mat_peptide 1424..1960
/gene="ORF1"
/product="p22"
mat_peptide 1961..2359
/gene="ORF1"
/product="VPg"
mat_peptide 2360..2902
/gene="ORF1"
/product="Pro"
mat_peptide 2903..4432
/gene="ORF1"
/product="RdRp"
gene 4416..6038
/gene="ORF2"
CDS 4416..6038
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="WDE42325.1"
/translation="MKMASSDVNPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSHNYTMNLASQNWSNYDPTEEIPAPLGTPDFVGKIQGML
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTNNDFEANQNTKFTPVGVIQDG
GTTHRNEPQQWVLPSYSGRNTPNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGAGRRRAL"
gene 6038..6844
/gene="ORF3"
CDS 6038..6844
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="WDE42326.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFPHDKEMLQAQIEATKRLQQEMMKDKQAMLLEGGFSETDATRGAIN
APMTKALDWSGTRYWAPDATTTTYNAGRFSTPQPSGALPGRANFRDAVPARGSSKKSS
NSSTATSVYSNQTVSTRLGATAGSGTSVSSFPSIARTRSWVEDQSRNLSPFIRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 gagaatgatt cagagaacaa caggcttctt cgggccgtac caggattgga acaggaaacc
61 cctccccact atggatgatt ccaaattaaa gaaggtagcc aatatattct tgtgcacttt
121 gtcttcacta ttcaccagac ccattaagga cataatagga aagttgaaac ctctcaacat
181 ccttaacatt ctggctacat gcgattggac cttcgcaggc atagtggaat ccttaatact
241 cttggcagaa ctctttggag ttttctggac acccccagat gtgtctgcga tgatcgcccc
301 cttgctaggt gattatgaac tgcaagggcc cgaggacctt gcagtggaac tggtcccaat
361 agtgatgggg gggataggtt tggtgctagg atttaccaaa gagaaaatcg gaaagatgct
421 gtcatccgct gcatccactt taagagcttg taaagacctt ggtgcatacg gactggagat
481 cttaaaattg gtcatgaaat ggttcttccc aaagaaagag gaagcaaatg aactggctat
541 ggtgagatcc atcgaggatg cagtactaga cctcgaggca attgaaaaca accatatgac
601 caccctgctc aaagacaaag acagcttggc aacctacatg agaacccttg accttgagga
661 ggagaaagcc agaaaactct caaccaaatc tgcttcaccc gatattgtgg gcacaatcaa
721 ctctcttctg gcaagaatcg ctgctgcacg ttccctagtg catcgggcga aagaagagct
781 ctccagcagg ccgaggcctg tcgttgtgat gatatcggga agaccaggga tagggaagac
841 tcaccttgct agggagctgg ccaagaagat cgcggcctcc ctcacagggg accagcgtgt
901 gggccttatc ccacgcaatg gtgtcgacca ctgggacgcg tacaagggcg aaagggttgt
961 cctatgggac gactatggaa tgagcaaccc catccatgat gcccttaggc tgcaggagct
1021 tgctgacact tgccccctca cgctaaattg tgacagaatt gagaacaaag gaaaagtctt
1081 tgatagtgat gccataatta ttactaccaa cctggccaac ccagcaccac tggattatgt
1141 caactttgaa gcgtgctcga gacgcattga tttcctcgtg tacgcagaag cccctgaggt
1201 ggagaaggca aagcgcgact tcccaggtca acctgacatg tggaagaacg ctttcagtcc
1261 tgacttctca cacataaaac tgtcattggc tccacagggt ggttttgaca agaatcggta
1321 caccccacat ggaaaagggg tcatgaagac cctcaccact ggctccctca tcgcccgggc
1381 atcagggtta ctccatgaga ggctagatga atatgaattg caaggcccag ccctcaccac
1441 tttcaacttt gaccgcaaca agatacttgc ttttagacag cttgctgctg aaaacaagta
1501 tgggctgatg gacacaatga gagttggaaa acagctcaag gatgtcaaga ctatgtcaga
1561 cctcaaacaa gcactcaaga acatcgcgat caagaagtgc cagatagtgt acaatggtgg
1621 cacctacaca cttgaggctg atggcaaggg cagcgtgaaa gttgacaaag tgcaaagtgc
1681 cactgtgcag accaacaatg aactagccgg tgccctacac cacctaagat gcgctagaat
1741 caggtactat gttaagtgcg tccaggaggc actgtattcc atcatccaaa tcgctggggc
1801 tgcattcgtc accacgcgca tcgctaagcg catgaatata cagaatctct ggtccaagcc
1861 acaggtggaa gacacagaag aggtggccaa caaagatggt tgcttaaaac ccaaagatga
1921 tgaagagttt gtcgtttcat ccgacgacat caaaactgag ggcaagaaag ggaagaacaa
1981 gtccggccgt gggcagaagc acacagcctt ttcaagtaaa gggctcagtg atgaagagta
2041 cgatgagtac aagagaatca gagaagaaag gaatggtaag tactccatag aagagtacct
2101 tcaagacaga gacaggtact acgaggaggt ggccattgcc agggcaaccg aagaggactt
2161 ctgtgaagaa gaagaggcca aaatccgaca gaggattttc agaccaacaa ggaaacaacg
2221 caaagaagag agggcttctc tcggcttggt cacaggatct gaaatcagga agagaaaccc
2281 agaagacttc aaacccaagg gaaagctgtg ggctgatgac gacagaagtg ttgactacaa
2341 tgagaaactc aactttgagg ccccaccaag catctggtcg cggatagtca actttggttc
2401 aggctggggc ttctgggtct cccccagtct gtttataaca tcaacccatg tcatacccca
2461 aggtgcaaag gagttcttcg gagtccctat caagcaaatc cagatacaca agtcaggtga
2521 attctgccga ttgagattcc caaagccaat cagaaccgat gtgacgggca tgattctaga
2581 agaaggcgcg cctgagggga ccgtggccac actgctcatc aagagaccaa ctggagagct
2641 catgcctctg gcagccagga tggggaccca tgcaaccatg aaaattcagg ggcgcacagt
2701 tggagggcaa atgggtatgc tcctaacagg atccaacgcc aagagtatgg acctaggcac
2761 aacaccaggc gactgcggct gcccctacat ctacaagagg gggaatgact acgtggtcat
2821 tggggtccat acggctgctg cccgtggagg aaacactgtc atatgtgcca cccagggaaa
2881 tgagggagag gccacacttg aaggaggtga cagtaaaggg acatactgtg gcgcgccaat
2941 cttaggccca gggagcgctc cgaagctcag caccaagact aagttttgga gatcatccac
3001 aacaccactc ccgcctggca cctacgaacc agcctacctc ggtggcaaag accctagagt
3061 caaaggtggc ccttcattgc aacaagttat gagggaccag ctgaagccat tcacagaacc
3121 cagaggcaaa ccaccaagac caaatgtgtt ggaagctgcc aagaaaacca tcatcaatgt
3181 ccttgagcaa acaattgatc caccccaaaa atggtcattt gcgcaagctt gcgcatccct
3241 tgacaaaacc acctccagcg gccacccgca ccacatgcgg aaaaacgact gttggaatgg
3301 ggagtccttc acaggaaagt tggctgacca agcctccaag gccaacctaa tgtttgaaga
3361 gggaaagaac atgactccag tctatacagg tgcacttaaa gatgagttgg taaagaccga
3421 taaagtgtat ggtaaggtca agaagaggct tctatggggt tcagatctgg cgaccatggt
3481 acggtgcgcc cgagcttttg gaggcctcat ggatgaactc aaggcacact gtgtcacact
3541 ccctgtcaga gttggtataa acatgaatga ggatggcccc atcatcttcg agaagcactc
3601 cagatataga tatcattatg atgctgacta ttcccggtgg gactcaacac aacaaaggga
3661 tgtgctggca gcagcactag agatcatggt taagttctct ccagaaccac acctggccca
3721 gatagttgca gaagacctcc tttcccctag cgtgatggat gtgggtgact ttcaaatatc
3781 aataagtgag ggtctcccct ctggggtgcc ttgcacctcc cagtggaatt ccatcgccca
3841 ctggctcctc actctctgtg cgctctctga agtcacggac ctgtcccctg atattattca
3901 ggccaactcc cttttctcct tctatggtga tgatgagatt gtaagcacgg acataaagtt
3961 ggacccagag aggctaacag caaaactcaa ggagtacggg ctgaaaccaa cccgccccga
4021 caaaactgaa ggaccccttg ttatctctga agacctggat ggtctgacat tcctccggag
4081 aactgtgacc cgtgacccag ctggctggtt tggaaaattg gaacaaagtt caattcttag
4141 gcaaatgtac tggaccacgg gtcccaacca tgaagaccca tttgaaacaa tgataccaca
4201 ctcccaaaga cccatacaat tgatgtcctt gctgggcgag gctgcactcc acggcccggc
4261 attctacagc aaaattagca aattagtcat tgcagagttg aaggaaggtg gcatggattt
4321 ttacgtgccc agacaagagc caatgttcat atggatgaga ttctcagatc tgaccacgtg
4381 ggagggcgat cgcaatcttg ctgccagctt tgtgaatgaa gatggcgtcg agtgacgtca
4441 acccatctga tgggtccgca gccaacctcg tcccagaggt caacaatgag gtcatggctc
4501 tggagcccgt tgttggtgcc gccattgcgg cacctgtagc gggccaacaa aatgtaattg
4561 acccctggat tagaaacaat tttgtacaag cccctggtgg agagtttaca gtatccccta
4621 gaaacgctcc aggtgaaata ctatggagcg cgcccctggg ccctgatcta aatccctact
4681 tatctcattt ggccagaatg tacaatggtt atgcaggtgg ttttgaagtg caggtgattc
4741 tcgcggggaa cgcgttcacc gccgggaagg tcatatttgc agcagtccca ccaaattttc
4801 caactgaagg cttgagcccc agccaggtca ctatgttccc ccatatagta gtagatgtta
4861 ggcaactaga gcctgtgttg attcccttac ccgatgttag gaataatttc tatcattaca
4921 atcaatcaaa tgaccccacc attaagttga tagcaatgtt gtatacacca cttagggcta
4981 ataatgctgg ggatgacgtc ttcacagttt cttgccgagt tctcacgaga ccatcccccg
5041 actttgactt catatttcta gtgccaccca cagttgagtc aagaactaaa ccattctctg
5101 tcccagtttt gactgttgag gagatgacca attcaagatt ccccattcct ttggaaaagc
5161 tgttcacggg tcccagcagt gcctttgttg tccaaccaca aaatggtagg tgcacgactg
5221 atggcgtgct cctaggcacc acccaactgt ctcctgtcaa catctgcacc ttcagaggag
5281 atgtcaccca tatcacaggt agtcataact atacaatgaa tttggcttct caaaattgga
5341 gcaactacga cccaacagaa gaaatcccag cccctctagg gactccagac tttgtgggga
5401 agattcaagg catgcttacc caaaccacaa ggacagatgg ctcaacacgc ggccacaaag
5461 ccacagtgta cactgggagc gccgacttcg ctccaaaact gggtagagtt caatttgaaa
5521 ccgacacaaa caatgatttt gaggctaacc aaaacacaaa gttcacccca gttggtgtca
5581 tccaagatgg tggcaccacc catcgaaatg aacctcaaca gtgggtgctc ccaagttact
5641 caggcaggaa cactcctaat gtgcatctgg cccccgctgt ggctcccact tttccgggtg
5701 agcaactcct cttctttagg tccaccatgc ccggatgcag cgggtacccc aacatggatt
5761 tggattgtct gctcccccag gaatgggtgc agtacttcta ccaggaggca gccccagcac
5821 aatctgatgt ggctctgcta agatttgtga atccagacac aggtagggtt ttgtttgaat
5881 gtaagcttca taaatcaggc tatgttacag tggctcacac tggccaacat gatttggtta
5941 ttccccccaa tggttatttt agatttgatt cctgggtcaa ccagttttac acgcttgccc
6001 ccatgggaaa tggagcgggg cgtagacgtg cactataatg gctggagctt tctttgctgg
6061 attggcatct gatgtccttg gctctggact tggttccctt atcaatgctg gggctggggc
6121 catcaaccaa aaagttgagt ttgaaaataa cagaaaattg caacaagcat ccttccaatt
6181 tagcagcaat ctacaacagg cttcctttcc ccatgacaaa gagatgctcc aagcacaaat
6241 tgaggctacc aaaaggttac aacaggaaat gatgaaagat aagcaggcaa tgctcctaga
6301 gggtgggttc tctgagacag atgcaacccg cggggcaatc aacgccccta tgacaaaagc
6361 cttggactgg agcggcacaa ggtactgggc tcctgatgct acgactacaa catacaatgc
6421 aggccgcttt tccacccccc aaccatcagg ggcgctgcca ggaagagcta attttaggga
6481 tgctgtccct gctcggggtt cctctaaaaa gtcttctaac tcttctactg ctacttctgt
6541 gtactcaaat caaactgttt caacgagact tggtgctaca gctggttctg gtaccagtgt
6601 ctcgagcttc ccgtcaattg caaggactag gagctgggtt gaggatcaaa gcaggaattt
6661 gtcccctttc attagggggg cccacaacat atcgtttgtc accccaccat ctagcaggtc
6721 ctctagccaa ggcacagtct caaccgtgcc taaagaaatt ttggactcct ggactggcgc
6781 tttcaacacg cgcaggcagc cactcttcgc tcacattcgc aagcgagggg agtcacgggt
6841 gtaatgtgaa aagacaaaat tgattatctt tccttctttt a
//