Typing tool
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Typing tool
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Complete norovirus genomes
| OQ451915 | GII.4 Sydney | |
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| GII.P31 |
ORF1: 1..4413
ORF2: 4394..6016
ORF3: 6016..6822
LOCUS OQ451915 6857 bp RNA linear VRL 22-FEB-2023
DEFINITION Norovirus GII isolate Hu/CHN/2021/GII.P31-GII.4/SJZ8021
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION OQ451915
VERSION OQ451915.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 6857)
AUTHORS Chen,L.-N., Wang,S.-J., Wang,S.-M., Fu,X.-L., Zheng,W.-J.,
Hao,Z.-Y., Zhou,H.-S., Zhang,X.-J., Zhao,Y.-L., Qiu,C.,
Seidlein,Lv., Qiu,T.-Y. and Wang,X.-Y.
TITLE Molecular epidemiology analysis of symptomatic and asymptomatic
norovirus infections in Chinese infants
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 6857)
AUTHORS Chen,L.-N., Wang,S.-J., Wang,S.-M., Fu,X.-L., Zheng,W.-J.,
Hao,Z.-Y., Zhou,H.-S., Zhang,X.-J., Zhao,Y.-L., Qiu,C.,
Seidlein,Lv., Qiu,T.-Y. and Wang,X.-Y.
TITLE Direct Submission
JOURNAL Submitted (17-FEB-2023) Institutes of Biomedical Sciences, Fudan
University, Dongling Road, Shanghai, Shanghai 200032, China
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..6857
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/CHN/2021/GII.P31-GII.4/SJZ8021"
/isolation_source="fecal sample"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="China"
/collection_date="Feb-2022"
/note="genotype: GII.4"
gene <1..4413
/gene="ORF1"
CDS <1..4413
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="WDE42321.1"
/translation="GFFGPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDI
IGKLKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQG
PEDLAVELVPIVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKW
FFPKKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARK
LSTKSASPDIVGTINSLLARIAAARSLVHRAKEELSSRPRPVVVMISGRPGIGKTHLA
RELAKKIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELA
DTCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPE
VEKAKRDFPGQPDMWKNAFSPDFSHIKLSLAPQGGFDKKRYTPHGKGVMKTLTTGSLI
ARASGLLHERLDEYELQGPALTTFNFDRNKILAFRQLAAENKYGLMDTMRVGKQLKDV
KTMSDLKQALKNIAIKKCQIVYNGGTYTLEADGKGSVKVDKVQSATVQTNNELAGALH
HLRCARIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVEDTEEVANK
DGCLKPKDDEEFVVSSDDIKTEGKKGKNKSGRGQKHTAFSSKGLSDEEYDEYKRIREE
RNGKYSIEEYLQDRDRYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASL
GLVTGSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLNFEAPPSIWSRIVNFGSGWGFW
VSPSLFITSTHVIPQGAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGA
PEGTVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTT
PGDCGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGNEGEATLEGGDSKGTYCGAP
ILGPGSAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPF
TEPRGKPPRPNVLEAAKKTIINVLEQTIDPPQKWSFAQACASLDKTTSSGHPHHMRKN
DCWNGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKVYGKVKKRLLWG
SDLATMVRCARAFGGLMDELKAHCVTLPVRVGINMNEDGPIIFEKHSRYRYHYDADYS
RWDSTQQRDVLAAALEIMVKFSPEPHLAQIVAEDLLSPSVMDVGDFQISISEGLPSGV
PCTSQWNSIAHWLLTLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPERLTA
KLKEYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWT
RGPNHEDPFETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVP
RQEPMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..303
/gene="ORF1"
/product="p48"
mat_peptide 304..1401
/gene="ORF1"
/product="NTPase"
mat_peptide 1402..1938
/gene="ORF1"
/product="p22"
mat_peptide 1939..2337
/gene="ORF1"
/product="VPg"
mat_peptide 2338..2880
/gene="ORF1"
/product="Pro"
mat_peptide 2881..4410
/gene="ORF1"
/product="RdRp"
gene 4394..6016
/gene="ORF2"
CDS 4394..6016
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="WDE42322.1"
/translation="MKMASSDVNPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSHNYTMNLASQNWSNYDPTEEIPAPLGTPDFVGKIQGML
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTNNDFEANQNTKFTPVGVIQDG
GTTHRNEPQQWVLPSYSGRNTPNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGAGRRRAL"
gene 6016..6822
/gene="ORF3"
CDS 6016..6822
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="WDE42323.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKRLQQEMMKVKQAMLLEGGFSETDATRGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRANFRDAVPARGSSKKSS
NSSTATSVYSNQTVSTRLGATAGSGTSVSSFPSIARTRSWVEDQSRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 ggcttcttcg ggccgtacca ggattggaac aggaaacccc tccccactat ggatgattcc
61 aaattaaaga aggtagccaa tatattcttg tgcactttgt cttcactatt caccagaccc
121 attaaggaca taataggaaa gttgaaacct ctcaacatcc ttaacattct ggctacatgc
181 gattggacct tcgcaggcat agtggaatcc ttaatactct tggcagaact ctttggagtt
241 ttctggacac ccccagatgt gtctgcgatg atcgccccct tgctaggtga ttatgaactg
301 caagggcccg aggaccttgc agtggaactg gtcccaatag tgatgggggg gataggtttg
361 gtgctaggat ttaccaaaga gaaaatcgga aagatgctgt catccgctgc atccacttta
421 agagcttgta aagaccttgg tgcatacgga ctggagatct taaaattggt catgaaatgg
481 ttcttcccaa agaaagagga agcaaatgaa ctggctatgg tgagatccat cgaggatgca
541 gtactagacc tcgaggcaat tgaaaacaac catatgacca ccctgctcaa agacaaagac
601 agcttggcaa cctacatgag aacccttgac cttgaggagg agaaagccag aaaactctca
661 accaaatctg cttcacccga tattgtgggc acaatcaact ctcttctggc aagaatcgct
721 gctgcacgct ccctagtgca tcgggcgaaa gaagagctct ccagcaggcc gagacctgtc
781 gttgtaatga tatcgggaag accagggata gggaaaactc accttgccag ggagctggcc
841 aagaagatcg cggcctccct cacaggggac cagcgtgtgg gccttatccc acgcaatggt
901 gtcgaccact gggacgcata caagggcgaa agggttgtcc tatgggacga ctatggaatg
961 agcaacccca tccatgatgc ccttaggttg caggagcttg ctgacacttg ccccctcacg
1021 ctaaattgtg acagaattga gaacaaagga aaagtctttg acagtgatgc cataattatc
1081 accaccaacc tggccaaccc agcaccactg gattatgtca actttgaagc gtgttcgaga
1141 cgcattgatt tcctcgtgta cgcagaagcc cctgaggtgg agaaggcaaa gcgcgacttc
1201 ccaggtcaac ctgacatgtg gaaaaacgct tttagtcctg acttctcaca cataaaactg
1261 tcattggctc cacagggtgg ttttgacaag aaacggtaca ccccacatgg aaaaggggtc
1321 atgaagaccc tcaccactgg ctccctcatc gcccgggcat cagggttact ccatgagagg
1381 ctagatgaat atgaattgca aggcccagcc ctcaccactt tcaactttga ccgcaacaag
1441 atacttgctt ttagacagct tgctgctgaa aacaagtatg ggctgatgga cacaatgaga
1501 gttggaaaac agctcaagga tgtcaagact atgtcagacc tcaaacaagc actcaagaac
1561 atcgcgatca agaagtgcca gatagtgtac aatggtggca cctacacact tgaggctgat
1621 ggcaagggca gcgtgaaagt tgacaaagtg caaagtgcca ctgtgcagac caacaatgaa
1681 ctagccggtg ccctacacca cctaagatgc gctagaatca ggtactatgt taagtgcgtc
1741 caggaggcac tgtattccat catccaaatc gctggggctg cattcgtcac cacgcgcatc
1801 gctaagcgca tgaatataca gaatctctgg tccaagccac aggtggaaga cacagaagag
1861 gtggccaaca aagatggttg cttaaaaccc aaagatgatg aagagtttgt cgtttcatcc
1921 gacgacatca aaactgaggg caagaaaggg aagaacaagt ccggccgtgg gcagaagcac
1981 acagcctttt caagtaaagg gctcagtgat gaagagtacg atgagtacaa gagaatcaga
2041 gaagaaagga atggtaagta ctccatagaa gagtaccttc aagacagaga caggtactac
2101 gaggaggtgg ccattgccag ggcaaccgaa gaggacttct gtgaagaaga agaggccaaa
2161 atccgacaga ggattttcag accaacaagg aaacaacgca aagaagagag ggcttctctc
2221 ggcttggtca caggatctga aatcaggaag agaaacccag aagacttcaa acccaaggga
2281 aagctgtggg ctgatgacga cagaagtgtt gactacaatg agaaactcaa ctttgaggcc
2341 ccaccaagca tctggtcgcg gatagtcaac tttggttcag gctggggctt ctgggtctcc
2401 cccagtctgt ttataacatc aacccatgtc ataccccaag gtgcaaagga gttcttcgga
2461 gtccctatca agcaaatcca gatacacaag tcaggtgaat tctgccgatt gagattccca
2521 aagccaatca gaaccgatgt gacgggcatg attctagaag aaggcgcgcc tgaggggacc
2581 gtggccacac tgctcatcaa gagaccaact ggagagctca tgcctctggc agccaggatg
2641 gggacccatg caaccatgaa aattcagggg cgcacagttg gagggcaaat gggtatgctc
2701 ctaacaggat ccaacgccaa gagtatggac ctaggcacaa caccaggcga ctgcggctgc
2761 ccctacatct acaagagggg gaatgactac gtggtcattg gggtccatac ggctgctgcc
2821 cgtggaggaa acactgtcat atgtgccacc cagggaaatg agggagaggc cacacttgaa
2881 ggaggtgaca gtaaagggac atactgtggc gcgccaatct taggcccagg gagcgctccg
2941 aagctcagca ccaagactaa gttttggaga tcatccacaa caccactccc gcctggcacc
3001 tacgaaccag cctacctcgg tggcaaagac cctagagtca aaggtggccc ttcattgcaa
3061 caagttatga gggaccagct gaagccattc acagaaccca gaggcaaacc accaagacca
3121 aatgtgttgg aagctgccaa gaaaaccatc atcaatgtcc ttgagcaaac aattgatcca
3181 ccccaaaaat ggtcatttgc gcaagcttgc gcatcccttg acaaaaccac ctccagcggc
3241 cacccgcacc acatgcggaa aaacgactgt tggaatgggg agtccttcac aggaaagttg
3301 gctgaccaag cctccaaggc caacctaatg tttgaagagg gaaagaacat gactccagtc
3361 tatacaggtg cacttaaaga tgagttggta aagaccgata aagtgtatgg taaggtcaag
3421 aagaggcttc tatggggttc agatctggcg accatggtac ggtgcgcccg agcttttgga
3481 ggcctcatgg atgaactcaa ggcacactgt gtcacactcc ctgtcagagt tggtataaac
3541 atgaatgagg atggccccat catcttcgag aagcactcca gatatagata tcattatgat
3601 gctgactatt cccggtggga ctcaacacaa caaagggatg tgctggcagc agcactagag
3661 atcatggtta agttctctcc agaaccacac ctggcccaga tagttgcaga agacctcctt
3721 tcccctagcg tgatggatgt gggtgacttt caaatatcaa taagtgaggg tctcccctct
3781 ggggtgcctt gcacctccca gtggaattcc atcgcccact ggctcctcac tctctgtgcg
3841 ctctctgaag tcacggacct gtcccctgat attattcagg ccaactccct tttctccttc
3901 tatggtgatg atgagattgt aagcacggac ataaagttgg acccagagag gctaacagca
3961 aaactcaagg agtacgggct gaaaccaacc cgccccgaca aaactgaagg accccttgtt
4021 atctctgaag acctggatgg tctgacattc ctccggagaa ctgtgacccg tgacccagct
4081 ggctggtttg gaaaattgga acaaagttca attcttaggc aaatgtactg gaccaggggt
4141 cccaaccatg aagacccatt tgaaacaatg ataccacact cccaaagacc catacaattg
4201 atgtccttgc tgggcgaggc tgcactccac ggcccggcat tctacagcaa aattagcaaa
4261 ttagtcattg cagagttgaa ggaaggtggc atggattttt acgtgcccag acaagagcca
4321 atgttcagat ggatgagatt ctcagatctg agcacgtggg agggcgatcg caatcttgct
4381 cccagctttg tgaatgaaga tggcgtcgag tgacgtcaac ccatctgatg ggtccgcagc
4441 caacctcgtc ccagaggtca acaatgaggt catggctctg gagcccgttg ttggtgccgc
4501 cattgcggca cctgtagcgg gccaacaaaa tgtaattgac ccctggatta gaaacaattt
4561 tgtacaagcc cctggtggag agtttacagt atcccctaga aacgctccag gtgaaatact
4621 atggagcgcg cccctgggcc ctgatctaaa tccctactta tctcatttgg ccagaatgta
4681 caatggttat gcaggtggtt ttgaagtgca ggtgattctc gcggggaacg cgttcaccgc
4741 cgggaaggtc atatttgcag cagtcccacc aaattttcca actgaaggct tgagccccag
4801 ccaggtcact atgttccccc atatagtagt agatgttagg caactagagc ctgtgttgat
4861 tcccttaccc gatgttagga ataatttcta tcattacaat caatcaaatg accccaccat
4921 taagttgata gcaatgttgt atacaccact tagggctaat aatgctgggg atgacgtctt
4981 cacagtttct tgccgagttc tcacgagacc atcccccgac tttgacttca tatttctagt
5041 gccacccaca gttgagtcaa gaactaaacc attctctgtc ccagttttga ctgttgagga
5101 gatgaccaat tcaagattcc ccattccttt ggaaaagctg ttcacgggtc ccagcagtgc
5161 ctttgttgtc caaccacaaa atggtaggtg cacgactgat ggcgtgctcc taggcaccac
5221 ccaactgtct cctgtcaaca tctgcacctt cagaggagat gtcacccata tcacaggtag
5281 tcataactat acaatgaatt tggcttctca aaattggagc aactacgacc caacagaaga
5341 aatcccagcc cctctaggga ctccagactt tgtggggaag attcaaggca tgcttaccca
5401 aaccacaagg acagatggct caacacgcgg ccacaaagcc acagtgtaca ctgggagcgc
5461 cgacttcgct ccaaaactgg gtagagttca atttgaaacc gacacaaaca atgattttga
5521 ggctaaccaa aacacaaagt tcaccccagt tggtgtcatc caagatggtg gcaccaccca
5581 tcgaaatgaa cctcaacagt gggtgctccc aagttactca ggcaggaaca ctcctaatgt
5641 gcatctggcc cccgctgtgg ctcccacttt tccgggtgag caactcctct tctttaggtc
5701 caccatgccc ggatgcagcg ggtaccccaa catggatttg gattgtctgc tcccccagga
5761 atgggtgcag tacttctacc aggaggcagc cccagcacaa tctgatgtgg ctctgctaag
5821 atttgtgaat ccagacacag gtagggtttt gtttgaatgt aagcttcata aatcaggcta
5881 tgttacagtg gctcacactg gccaacatga tttggttatt ccccccaatg gttattttag
5941 atttgattcc tgggtcaacc agttttacac gcttgccccc atgggaaatg gagcggggcg
6001 tagacgtgca ctataatggc tggagctttc tttgctggat tggcatctga tgtccttggc
6061 tctggacttg gttcccttat caatgctggg gctggggcca tcaaccaaaa agttgagttt
6121 gaaaataaca gaaaattgca acaagcatcc ttccaattta gcagcaatct acaacaggct
6181 tcctttcaac atgacaaaga gatgctccaa gcacaaattg aggctaccaa aaggttacaa
6241 caggaaatga tgaaagttaa gcaggcaatg ctcctagagg gtgggttctc tgagacagat
6301 gcaacccgcg gggcaatcaa cgcccctatg acaaaagcct tggactggag cgggacaagg
6361 tactgggctc ctgatgctag gactacaaca tacaatgcag gccgcttttc caccccccaa
6421 ccatcagggg cgctgccagg aagagctaat tttagggatg ctgtccctgc tcggggttcc
6481 tctaaaaagt cttctaactc ttctactgct acttctgtgt actcaaatca aactgtttca
6541 acgagacttg gtgctacagc tggttctggt accagtgtct cgagcttccc gtcaattgca
6601 aggactagga gctgggttga ggatcaaagc aggaatttgt cccctttcat gaggggggcc
6661 cacaacatat cgtttgtcac cccaccatct agcaggtcct ctagccaagg cacagtctca
6721 accgtgccta aagaaatttt ggactcctgg actggcgctt tcaacacgcg caggcagcca
6781 ctcttcgctc acattcgcaa gcgaggggag tcacgggtgt aatgtgaaaa gacaaaattg
6841 attatctttc ctttctt
//