Typing tool
|
|
|
|
|
|
Typing tool
|
Complete norovirus genomes
| OQ451912 | GII.4 Sydney | |
|
|---|---|---|---|
| GII.P31 |
ORF1: 1..4413
ORF2: 4394..6016
ORF3: 6016..6822
LOCUS OQ451912 6859 bp RNA linear VRL 22-FEB-2023
DEFINITION Norovirus GII isolate Hu/CHN/2022/GII.P31-GII.4/SJZ7488
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION OQ451912
VERSION OQ451912.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 6859)
AUTHORS Chen,L.-N., Wang,S.-J., Wang,S.-M., Fu,X.-L., Zheng,W.-J.,
Hao,Z.-Y., Zhou,H.-S., Zhang,X.-J., Zhao,Y.-L., Qiu,C.,
Seidlein,Lv., Qiu,T.-Y. and Wang,X.-Y.
TITLE Molecular epidemiology analysis of symptomatic and asymptomatic
norovirus infections in Chinese infants
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 6859)
AUTHORS Chen,L.-N., Wang,S.-J., Wang,S.-M., Fu,X.-L., Zheng,W.-J.,
Hao,Z.-Y., Zhou,H.-S., Zhang,X.-J., Zhao,Y.-L., Qiu,C.,
Seidlein,Lv., Qiu,T.-Y. and Wang,X.-Y.
TITLE Direct Submission
JOURNAL Submitted (17-FEB-2023) Institutes of Biomedical Sciences, Fudan
University, Dongling Road, Shanghai, Shanghai 200032, China
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..6859
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/CHN/2022/GII.P31-GII.4/SJZ7488"
/isolation_source="fecal sample"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="China"
/collection_date="Feb-2022"
/note="genotype: GII.4"
gene <1..4413
/gene="ORF1"
CDS <1..4413
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="WDE42312.1"
/translation="GFFGPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDI
IGKLKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQG
PEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKW
FFPKKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLTTYMRTLDLEEEKARK
LSTKSASPDIVGTINSLLARIAAARSLVHRAKEELSSRPRPVVVMISGRPGIGKTHLA
RELAKKIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELA
DTCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPE
VEKAKRDFPGQPDMWKNAFSPDFSHIKLSLAPQGGFDKIRHTPHGKGVMKTLTTGSLI
ARASGLLHERLDEYELQGPALTTFNFDRNKILAFRQLAAENKYGLMDTMRVGKQLKDV
KTMSDLKQALKNIAIKKCQIVYNGGTYTLEADGKGSVKVDKVQSATVQTNNELAGALH
HLRCARIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVEDTEEMANK
DGCLKPKDDEEFVVSSDDIKTEGKKGKNKSGRGQKHTAFSSKGLSDEEYDEYKRIREE
RNGKYSIEEYLQDRDRYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASL
GLVTGSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLNFEAPPSIWSRIVNFGSGWGFW
VSPSLFITSTHVIPQGAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGA
PEGTVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTT
PGDCGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDSKGTYCGAP
ILGPGSAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPF
TEPRGKPPRPNVLEAAKKTIINVLEQTIDPPQKWSFAQACASLDKTTSSGHPHHMRKN
DCWNGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKVYGKVKKRLLWG
SDLATMVRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYS
RWDSTQQRDVLAAALEIMVKFSPEPHLAQIVAEDLLSPSVMDVGDFQISISEGLPSGV
PCTSQWNSIAHWLLTLCVLSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPERLTA
KLKEYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQGSILRQMYWT
RGPNHEDPFETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVP
RQEPMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..303
/gene="ORF1"
/product="p48"
mat_peptide 304..1401
/gene="ORF1"
/product="NTPase"
mat_peptide 1402..1938
/gene="ORF1"
/product="p22"
mat_peptide 1939..2337
/gene="ORF1"
/product="VPg"
mat_peptide 2338..2880
/gene="ORF1"
/product="Pro"
mat_peptide 2881..4410
/gene="ORF1"
/product="RdRp"
gene 4394..6016
/gene="ORF2"
CDS 4394..6016
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="WDE42313.1"
/translation="MKMASSDVNPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSHNYTMNLASQNWSNYDPTEEIPAPLGTPDFVGKIQGML
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTNNDFEANQNTKFTPVGVIQDG
GTTHRNEPQQWVLPSYSGRNTPNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGAGRRRAL"
gene 6016..6822
/gene="ORF3"
CDS 6016..6822
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="WDE42314.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDREMLQAQIEATKRLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRANFRDAVPARGSSSKSS
NSSTATSVYSNQTTSTRLGSTAGSGTSVSSSPSTARTRSWVEDQSRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 ggcttcttcg ggccgtacca ggattggaac aggaaacccc tccccactat ggatgactcc
61 aaattaaaga aggtagccaa catattcttg tgcactttgt cttcactatt caccaggccc
121 attaaggaca taatagggaa gttgaaacct ctcaacatcc ttaatattct ggctacatgt
181 gattggacct tcgcaggcat agtggaatcc ttaatactct tggcagaact ctttggagtt
241 ttctggacac ccccagatgt gtctgcgatg atcgccccct tgcttggtga ttatgaactg
301 caaggacccg aggaccttgc agtggaactg gtcccagtag tgatgggggg gataggtttg
361 gtgctaggat ttaccaaaga gaagatcggt aaaatgttgt catccgctgc atccacttta
421 agagcttgca aagaccttgg tgcatacgga ctggaaatct taaaattggt catgaagtgg
481 ttcttcccaa agaaagagga agcaaatgaa ctggccatgg tgagatccat cgaggatgca
541 gtactagacc tcgaggcaat tgaaaacaac cacatgacca ccctgctcaa agacaaagac
601 agcttgacaa cctacatgag aacccttgac cttgaggagg agaaagccag aaaactctca
661 accaaatctg cttcacccga tattgtgggc acaatcaact ctcttctggc aagaatcgct
721 gctgcacgct ccctagtgca tcgggcgaaa gaagagctct ccagcaggcc gagacctgtc
781 gttgtaatga tatcgggaag accagggata ggaaaaactc accttgccag ggagctggcc
841 aagaagatcg cggcctccct cacaggggac cagcgtgtgg gccttatccc acgcaatggt
901 gtcgaccact gggacgcata caagggcgaa agggttgtcc tatgggacga ctatggaatg
961 agcaacccca tccatgatgc ccttaggttg caggagcttg ctgacacttg ccccctcacg
1021 ctaaattgtg acagaattga gaacaaagga aaagtctttg acagtgatgc cataattatc
1081 accaccaacc tggccaaccc agcaccactg gattatgtca actttgaagc gtgttcgaga
1141 cgcattgatt tcctcgtgta cgcagaagcc cctgaggtgg agaaggcaaa gcgcgacttc
1201 ccaggtcaac ctgacatgtg gaagaacgct ttcagtcctg acttctcaca cataaaactg
1261 tcattggctc cacagggtgg ttttgacaag atacggcaca ccccgcatgg aaaaggggtc
1321 atgaagaccc tcaccactgg ctccctcatc gcccgagcat cagggttact ccatgagaga
1381 ctagatgaat atgaattgca aggcccagcc ctcaccactt tcaactttga ccgcaacaag
1441 atactcgctt ttagacagct tgctgctgaa aacaagtatg ggctgatgga cacaatgaga
1501 gttggaaaac agctcaagga tgtcaagact atgtcagacc tcaaacaagc actcaagaac
1561 atcgcgatca agaagtgcca gatagtgtac aatggtggca cctacacact tgaggctgat
1621 ggcaagggca gtgtgaaagt tgataaagtg caaagtgcca ctgtgcagac caacaatgaa
1681 ctagccggtg ccctacacca cctaagatgc gctagaatca gatactatgt aaagtgcgtc
1741 caggaggcac tgtattccat catccaaatc gctggggctg cattcgtcac cacgcgcatc
1801 gctaagcgca tgaatataca gaatctctgg tccaagccac aggtggaaga cacagaagag
1861 atggccaaca aagatggttg cctaaaaccc aaagatgatg aagagtttgt cgtttcatcc
1921 gacgacatca aaactgaggg caagaaaggg aagaacaagt ccggccgtgg gcagaagcac
1981 acagcctttt caagtaaagg gctcagtgat gaggagtacg atgagtacaa gagaatcaga
2041 gaagaaagga atggtaagta ttccatagaa gagtaccttc aggacagaga caggtactac
2101 gaggaggtgg ccattgccag ggcaaccgaa gaggacttct gtgaagaaga agaggccaaa
2161 atccggcaga ggattttcag accaacaagg aaacaacgca aagaagagag ggcttctctc
2221 ggcttggtca caggttctga aatcaggaag agaaacccag aagacttcaa acccaaggga
2281 aagctgtggg ctgatgacga cagaagtgtt gactacaatg agaaactcaa ctttgaggcc
2341 ccaccaagca tctggtcgcg gatagtcaac tttggttcag gctggggctt ctgggtctcc
2401 cccagtctgt ttataacatc aacccatgtc ataccccaag gtgcaaagga gttcttcgga
2461 gtccctatca agcaaatcca gatacacaag tcaggtgaat tctgccgatt gagattccca
2521 aagccaatca gaaccgatgt gacgggcatg attctagaag aaggtgcgcc cgaggggacc
2581 gtggccacac tgcttatcaa gagaccaact ggagagctca tgcctctggc agccagaatg
2641 gggacccatg caaccatgaa aattcagggg cgcacagttg gagggcaaat gggcatgctc
2701 ctgacaggat ctaacgccaa gagtatggac ctaggcacaa caccaggcga ctgcggctgc
2761 ccctacatct acaagagggg gaatgactac gtggtcatag gggtccatac ggctgctgcc
2821 cgtggaggaa acactgtcat atgtgccacc cagggaagtg agggagaggc cacacttgaa
2881 ggaggtgaca gtaaagggac atactgtggc gcgccaatct tgggcccagg gagcgctccg
2941 aagctcagca ctaagactaa gttttggaga tcatccacaa caccactccc acctggcacc
3001 tacgaaccag cctacctcgg tggcaaagac cctagagtca aaggtggccc ttcattgcaa
3061 caagttatga gggaccagct gaagccattc acagaaccca gaggcaaacc accaagacca
3121 aatgtgttgg aagctgccaa gaaaaccatc atcaatgtcc ttgagcaaac aattgatcca
3181 ccccaaaaat ggtcatttgc gcaagcttgc gcatcccttg acaaaaccac ctccagcggc
3241 cacccgcacc acatgcggaa aaacgactgt tggaatgggg agtccttcac aggaaagttg
3301 gctgaccaag cctccaaggc caacctaatg tttgaagagg gaaagaacat gactccagtc
3361 tatacaggtg cacttaaaga tgagttggta aagaccgata aagtgtatgg taaggtcaag
3421 aagaggcttc tatggggttc agatctggcg accatggtac ggtgcgcccg agcttttgga
3481 ggcctcatgg atgaactcaa ggcacactgt gtcacactcc ctgtcagagt tggtatgaac
3541 atgaatgagg atggccccat catcttcgag aagcactcca gatatagata tcattatgat
3601 gctgactatt cccggtggga ctcaacacaa caaagggatg tgctggcagc agcactagag
3661 atcatggtta agttctctcc agaaccacac ctggcccaga tagttgcaga agacctcctt
3721 tcccctagcg tgatggatgt gggtgacttt caaatatcaa taagtgaggg tctcccctct
3781 ggggtgcctt gcacctccca gtggaattcc atcgcccact ggctcctcac tctctgtgtg
3841 ctctctgaag tcacggacct gtcccctgat atcattcagg ccaactccct tttctccttc
3901 tatggtgatg atgagattgt aagcacagat ataaagttgg acccagagag gctaacagca
3961 aagctcaagg agtatgggct aaaaccaacc cgccccgaca aaactgaggg accccttgtc
4021 atctctgaag acctggatgg tctgacattc ctccggagaa ctgtgacccg tgatccagct
4081 ggctggtttg gaaaattgga acaaggttca attcttaggc aaatgtactg gaccaggggc
4141 cccaaccatg aagacccatt tgaaacaatg ataccacact cccaaagacc catacaattg
4201 atgtccttgc tgggcgaggc tgcactccac ggcccggcat tctacagcaa aattagcaaa
4261 ttagtcattg cagagttgaa ggaaggtggc atggattttt acgtgcccag acaagagcca
4321 atgttcagat ggatgagatt ctcagatctg agcacgtggg agggcgatcg caatctggct
4381 cccagttttg tgaatgaaga tggcgtcgag tgacgtcaac ccatctgatg ggtccgcagc
4441 caacctcgtc ccagaggtca acaatgaggt tatggctctg gagcccgttg ttggtgccgc
4501 cattgcggca cctgtagcgg gccaacaaaa tgtaattgac ccctggatta gaaacaattt
4561 tgtacaagcc cctggtggag agtttacagt atcccctaga aacgctccag gtgaaatact
4621 atggagcgcg cccttgggcc ctgatctaaa tccctacttg tctcatttgg ccagaatgta
4681 caatggttat gcaggtggtt ttgaagtgca ggtaatcctc gcggggaacg cgttcaccgc
4741 cgggaaggtc atatttgcag cagtcccacc aaatttccca actgaaggct tgagccccag
4801 ccaggtcact atgttccccc atatagtagt agatgttagg caactagaac ctgtgttgat
4861 tcccttaccc gatgttagga ataatttcta tcattacaat caatcaaatg accccaccat
4921 taagttgata gcaatgttgt atacaccact tagggctaat aatgctgggg atgatgtctt
4981 cacagtttct tgtcgagttc tcacgagacc atcccccgat tttgacttca tatttctagt
5041 gccacccaca gttgagtcaa ggactaaacc attctctgtc ccagttttga ctgttgagga
5101 gatgaccaat tcaagattcc ccattccttt ggaaaagttg ttcacgggtc ccagcagtgc
5161 ctttgttgtc caaccacaaa atggtagatg cacgactgat ggcgtgctcc taggcaccac
5221 ccaactgtct cctgtcaaca tctgcacctt cagaggagat gtcacccata tcacaggtag
5281 tcataactat acaatgaatt tggcttctca aaattggagc aactacgacc caacagaaga
5341 aataccagcc cctctaggga ctccagactt tgtggggaag atacaaggca tgctcaccca
5401 aaccacaagg acagatggct caacacgcgg ccacaaagcc acagtgtaca ctgggagcgc
5461 cgactttgct ccaaaactgg gtagagttca atttgaaact gacacaaaca atgattttga
5521 ggctaaccaa aacacaaagt tcaccccagt tggtgtcatc caagatggtg gcaccactca
5581 tcgaaatgaa ccccaacagt gggtgctccc aagttactca ggcaggaaca ctcctaatgt
5641 gcatctggcc cccgctgtgg cccccacttt tccgggtgag caactccttt tctttagatc
5701 caccatgccc ggttgcagcg ggtaccccaa catggatttg gattgtctgc tcccccagga
5761 atgggtacag tacttctacc aggaggcagc cccagcacaa tctgatgtgg ctctgctaag
5821 atttgtgaat ccagacacag gtagggtttt gtttgaatgt aagcttcata aatcaggcta
5881 tgtcacagtg gctcacactg gccaacatga tttggttatc ccccccaatg gttattttag
5941 gtttgattcc tgggtcaacc agttttacac acttgccccc atgggaaatg gagcggggcg
6001 tagacgtgca ctataatggc tggagctttc tttgctggat tggcatctga tgttcttggc
6061 tctggacttg gttcccttat caatgctggg gctggggcca tcaaccaaaa agttgagttt
6121 gaaaataata gaaaattgca gcaagcatcc ttccaattta gcagcaatct acaacaggct
6181 tcctttcaac atgacagaga gatgctccaa gcacaaattg aggctaccaa aaggttacaa
6241 caggaaatga tgaaagttaa gcaggcaatg ctcctagagg gtgggttctc tgagacagat
6301 gcagcccgcg gggcaatcaa cgcccctatg acaaaagcct tggactggag cgggacaagg
6361 tactgggctc ctgatgctag gactacaaca tacaatgcag gccgcttttc caccccccaa
6421 ccatcggggg cgctgccagg aagagctaat tttagggatg ctgtccctgc tcggggttcc
6481 tctagtaagt cttctaattc ttctactgct acttctgtgt attcaaatca aacaacttca
6541 acgagacttg gttctacagc tggttctggt accagtgtct cgagctcccc gtcaactgca
6601 aggactagga gctgggttga ggaccaaagt aggaacttgt cacctttcat gaggggggcc
6661 cacaacatat cgtttgtcac cccaccatct agcaggtcct ctagccaagg cacagtctca
6721 accgtgccta aagagatttt ggactcctgg actggcgctt tcaacacgcg caggcagcca
6781 ctcttcgctc acattcgtaa gcgaggggag tcacgggcgt aatgtgaaaa ggcaaaattg
6841 attatctttc cttctttaa
//