Typing tool
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Typing tool
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Complete norovirus genomes
| OQ451906 | GII.4 Sydney | |
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| GII.P31 |
ORF1: 1..4415
ORF2: 4396..6018
ORF3: 6018..6824
LOCUS OQ451906 6861 bp RNA linear VRL 22-FEB-2023
DEFINITION Norovirus GII isolate Hu/CHN/2021/GII.P31-GII.4/SJZ1007
nonstructural polyprotein (ORF1) gene, partial cds; and VP1 (ORF2)
and VP2 (ORF3) genes, complete cds.
ACCESSION OQ451906
VERSION OQ451906.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 6861)
AUTHORS Chen,L.-N., Wang,S.-J., Wang,S.-M., Fu,X.-L., Zheng,W.-J.,
Hao,Z.-Y., Zhou,H.-S., Zhang,X.-J., Zhao,Y.-L., Qiu,C.,
Seidlein,Lv., Qiu,T.-Y. and Wang,X.-Y.
TITLE Molecular epidemiology analysis of symptomatic and asymptomatic
norovirus infections in Chinese infants
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 6861)
AUTHORS Chen,L.-N., Wang,S.-J., Wang,S.-M., Fu,X.-L., Zheng,W.-J.,
Hao,Z.-Y., Zhou,H.-S., Zhang,X.-J., Zhao,Y.-L., Qiu,C.,
Seidlein,Lv., Qiu,T.-Y. and Wang,X.-Y.
TITLE Direct Submission
JOURNAL Submitted (17-FEB-2023) Institutes of Biomedical Sciences, Fudan
University, Dongling Road, Shanghai, Shanghai 200032, China
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..6861
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Hu/CHN/2021/GII.P31-GII.4/SJZ1007"
/isolation_source="fecal sample"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="China"
/collection_date="Feb-2022"
/note="genotype: GII.4"
gene <1..4415
/gene="ORF1"
CDS <1..4415
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="WDE42294.1"
/translation="GLFGPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDI
IGKLKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQG
PEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKW
FFPKKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLTTYMRTLDLEEEKARK
LSTKSASPDIVGTINSLLARIAAARSLVHRAKEELSSRPRPVVVMISGRPGIGKTHLA
RELAKKIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELA
DTCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPE
VEKAKRDFPGQPDMWKNAFSPDFSHIKLSLAPQGGFDKRRHTPHGKGVMKTLTTGSLI
ARASGLLHERLDEYELQGPALTTFNFDRNKILAFRQLAAENKYGLMDTMRVGKQLKDV
KTMSDLKQALKNIAIKKCQIVYNGGTYTLEADGKGSVKVDKVQSATVQTNNELAGALH
HLRCARIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVEDTEEVANK
DGCLKPKDDEEFVVSSDDIKTEGKKGKNKSGRGQKHTAFSSKGLSDEEYDEYKRIREE
RNGKYSIEEYLQDRDRYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASL
GLVTGSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLNFEAPPSIWSRIVNFGSGWGFW
VSPSLFITSTHVIPQGAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGA
PEGTVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTT
PGDCGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDSKGTYCGAP
ILGPGSAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPF
TEPRGKPPRPNVLEAAKKTIINVLEQTIDPPQKWSFAQACASLDKTTSSGHPHHMRKN
DCWNGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKVYGKVKKRLLWG
SDLATMVRCARAFGGLMDELKAHCVTLPVRVGINMNEDGPIIFEKHSRYRYHYDADYS
RWDSTQQRDVLAAALEIMVKFSPEPHLAQIVAEDLLSPSVMDVGDFQISISEGLPSGV
PCTSQWNSIAHWLLTLCVLSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPERLTA
KLKEYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQGSILRQMYWT
RGPNHEDPFETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVP
RQEPMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..305
/gene="ORF1"
/product="p48"
mat_peptide 306..1403
/gene="ORF1"
/product="NTPase"
mat_peptide 1404..1940
/gene="ORF1"
/product="p22"
mat_peptide 1941..2339
/gene="ORF1"
/product="VPg"
mat_peptide 2340..2882
/gene="ORF1"
/product="Pro"
mat_peptide 2883..4412
/gene="ORF1"
/product="RdRp"
gene 4396..6018
/gene="ORF2"
CDS 4396..6018
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="WDE42295.1"
/translation="MKMASSDVNPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSHNYTMNLASQNWSNYDPTEEIPAPLGTPDFVGKIQGML
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTNNDFEANQNTKFTPVGVIQDG
GTTHRNEPQQWVLPSYSGRNTPNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGAGRRRAL"
gene 6018..6824
/gene="ORF3"
CDS 6018..6824
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="WDE42296.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKRLQRETMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPGRANFRDAVPARGSSSKSS
NSSTATSVYSNQTTSTRLGSTAGSGTSVSSFPSTARTRSWVEDQSRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 tggggctctt cgggccgtac caggattgga acaggaaacc cctccccact atggatgact
61 ccaaattaaa gaaggtagcc aacatattct tgtgcacttt gtcttcacta ttcaccaggc
121 ccattaagga cataataggg aagttgaaac ctctcaacat ccttaatatt ctggctacat
181 gtgattggac cttcgcaggc atagtggaat ccttaatact cttggcagaa ctctttggag
241 ttttctggac acccccagat gtgtctgcga tgatcgcccc cttgcttggt gattatgaac
301 tgcaaggacc cgaggacctt gcagtggaac tggtcccagt agtgatgggg gggataggtt
361 tggtgctagg atttaccaaa gagaagatcg gtaaaatgtt gtcatccgct gcatccactt
421 taagagcttg caaagacctt ggtgcatacg gactggaaat cttaaaattg gtcatgaagt
481 ggttcttccc aaagaaagag gaagcaaatg aactggccat ggtgagatcc atcgaggatg
541 cagtactaga cctcgaggca attgaaaaca accacatgac caccctgctc aaagacaaag
601 acagcttgac aacctacatg agaacccttg accttgagga ggagaaagcc agaaaactct
661 caaccaaatc tgcttcaccc gatattgtgg gcacaatcaa ctctcttctg gcaagaatcg
721 ctgctgcacg ctccctagtg catcgggcga aagaagagct ctccagcagg ccgagacctg
781 tcgttgtaat gatatcggga agaccaggga taggaaaaac tcaccttgcc agggagctgg
841 ccaagaagat cgcggcctcc ctcacagggg accagcgtgt gggccttatc ccacgcaatg
901 gtgtcgacca ctgggacgca tacaagggcg aaagggttgt cctatgggac gactatggaa
961 tgagcaaccc catccatgat gcccttaggt tgcaggagct tgctgacact tgccccctca
1021 cgctaaattg tgacagaatt gagaacaaag gaaaagtctt tgacagtgat gccataatta
1081 tcaccaccaa cctggccaac ccagcaccac tggattatgt caactttgaa gcgtgttcga
1141 gacgcattga tttcctcgtg tacgcagaag cccctgaggt ggagaaggca aagcgcgact
1201 tcccaggtca acctgacatg tggaagaacg ctttcagtcc tgacttctca cacataaaac
1261 tgtcattggc tccacagggt ggttttgaca agagacggca caccccgcat ggaaaagggg
1321 tcatgaagac cctcaccact ggctccctca tcgcccgagc atcagggttg ctccatgaga
1381 ggctagatga atatgaattg caaggcccag ccctcaccac tttcaacttt gaccgcaaca
1441 agatactcgc ttttagacag cttgctgctg aaaacaagta tgggctgatg gacacaatga
1501 gagttggaaa acagctcaag gatgtcaaga ctatgtcaga cctcaaacaa gcactcaaga
1561 acatcgcgat caagaagtgc cagatagtgt acaatggtgg cacctacaca cttgaggctg
1621 atggcaaggg cagtgtgaaa gttgataaag tgcaaagtgc cactgtgcag accaacaatg
1681 aactagccgg tgccctacac cacctaagat gcgctagaat cagatactat gttaagtgcg
1741 tccaggaggc actgtattcc atcatccaaa tcgctggggc tgcattcgtc accacgcgca
1801 tcgctaagcg catgaatata cagaatctct ggtccaagcc acaggtggaa gacacagaag
1861 aggtggccaa caaagatggt tgcctaaaac ccaaagatga tgaagagttt gtcgtttcat
1921 ccgacgacat caaaactgag ggcaagaaag ggaagaacaa gtccggccgt gggcagaagc
1981 acacagcctt ttcaagtaaa gggctcagtg atgaggagta cgatgagtac aagagaatca
2041 gagaagaaag gaatggtaag tactccatag aagagtacct tcaggacaga gacaggtact
2101 acgaggaggt ggccattgcc agggcaaccg aagaggactt ctgtgaagaa gaagaggcca
2161 aaatccggca gaggattttc agaccaacaa ggaaacaacg caaagaagag agggcttctc
2221 tcggcttggt cacaggttct gaaatcagga agagaaaccc agaagacttc aaacccaagg
2281 gaaagctgtg ggctgatgac gacagaagtg ttgactacaa tgagaaactc aactttgagg
2341 ccccaccaag catctggtcg cggatagtca actttggttc aggctggggc ttctgggtct
2401 cccccagtct gtttataaca tcaacccatg tcatacccca aggtgcaaag gagttcttcg
2461 gagtccctat caagcaaatc cagatacaca agtcaggtga attctgccga ttgagattcc
2521 caaagccaat cagaaccgat gtgacgggca tgattctaga agaaggtgcg cccgagggga
2581 ccgtggccac actgctcatc aagagaccaa ctggagagct catgcctctg gcagccagaa
2641 tggggaccca tgcaaccatg aaaattcagg ggcgcacagt tggagggcaa atgggtatgc
2701 tcctgacagg atccaacgcc aagagtatgg acctaggcac aacaccaggt gactgcggct
2761 gcccctacat ctacaagagg gggaatgact acgtggtcat aggggtccat acggctgctg
2821 cccgtggagg aaacactgtc atatgtgcca cccagggaag tgagggagag gccacacttg
2881 aaggaggtga cagtaaaggg acatactgtg gcgcgccaat cttgggccca gggagcgctc
2941 cgaagctcag caccaagact aagttttgga gatcatccac aacaccactc ccacctggca
3001 cctacgaacc agcctacctc ggtggcaaag accctagagt caaaggtggc ccttcattgc
3061 aacaagttat gagggaccag ctgaagccat tcacagaacc cagaggcaaa ccaccaagac
3121 caaatgtgtt ggaagctgcc aagaaaacca tcatcaatgt ccttgagcaa acaattgatc
3181 caccccaaaa atggtcattt gcgcaagctt gcgcatccct tgacaaaacc acctccagcg
3241 gccacccgca ccacatgcgg aaaaacgact gttggaatgg ggagtccttc acaggaaagt
3301 tggctgacca agcctccaag gccaacctaa tgtttgaaga gggaaagaac atgactccag
3361 tctatacagg tgcacttaaa gatgagttgg taaagaccga taaagtgtat ggtaaggtca
3421 agaagaggct tctatggggt tcagatctgg cgaccatggt acggtgcgcc cgagcttttg
3481 gaggcctcat ggatgaactc aaggcacact gtgtcacact ccctgtcaga gttggtataa
3541 acatgaatga ggatggcccc atcatcttcg agaagcactc cagatataga tatcattatg
3601 atgctgacta ttcccggtgg gactcaacac aacaaaggga tgtgctggca gcagcactag
3661 agatcatggt taagttctct ccagaaccac acctggccca gatagttgca gaagacctcc
3721 tttcccctag cgtgatggat gtgggtgact ttcaaatatc aataagtgag ggtctcccct
3781 ctggggtgcc ttgcacctcc cagtggaatt ccatcgccca ctggctcctc actctctgtg
3841 tgctctctga agtcacggac ctgtcccctg atattattca ggccaactcc cttttctcct
3901 tctatggtga tgatgagatt gtaagcacag atataaagtt ggacccagag aggctaacag
3961 caaagctcaa ggagtacggg ctaaaaccaa cccgccccga caaaactgaa ggaccccttg
4021 tcatctctga agacctggat ggtctgacat tcctccggag aactgtgacc cgtgatccag
4081 ctggctggtt tggaaaattg gaacaaggtt caattcttag gcaaatgtac tggaccaggg
4141 gccccaacca tgaagaccca tttgaaacaa tgataccaca ctcccaaaga cccatacaat
4201 tgatgtcctt gctgggcgag gctgcactcc acggcccggc attctacagc aaaattagca
4261 aattagtcat tgcagagttg aaggaaggtg gcatggattt ttacgtgccc agacaagagc
4321 caatgttcag atggatgaga ttctcagatc tgagcacgtg ggagggcgat cgcaatctgg
4381 ctcccagttt tgtgaatgaa gatggcgtcg agtgacgtca acccatctga tgggtccgca
4441 gccaacctcg tcccagaggt caacaatgag gttatggctc tggagcccgt tgttggtgcc
4501 gccattgcgg cacctgtagc gggccaacaa aatgtaattg acccctggat tagaaacaat
4561 tttgtacaag cccctggtgg agagttcaca gtatccccta gaaacgctcc aggtgaaata
4621 ctatggagcg cgcccttggg ccctgatctg aatccctact tgtctcattt ggccagaatg
4681 tacaatggtt atgcaggtgg ttttgaagtg caggtaatcc tcgcggggaa cgcgttcacc
4741 gccgggaagg tcatatttgc agcagtccca ccaaatttcc caactgaagg cttgagcccc
4801 agccaggtca ctatgttccc ccatatagta gtagatgtta ggcaactaga acctgtgttg
4861 attcccttac ccgatgttag gaataatttc tatcactaca atcaatcaaa tgaccccact
4921 attaagttga tagcaatgtt gtatacacca cttagggcta ataatgctgg ggatgatgtc
4981 ttcacagttt cttgtcgagt tctcacgaga ccatcccccg attttgactt catatttcta
5041 gtgccaccca cagttgagtc aaggactaaa ccattctctg tcccagtttt gactgttgag
5101 gagatgacca attcaagatt ccccattccc ttggaaaagt tgttcacggg tcccagcagt
5161 gccttcgttg tccaaccaca aaatggtagg tgcacgactg atggcgtgct cctaggcacc
5221 acccaactgt ctcctgtcaa catctgcacc ttcagaggag atgtcaccca tatcacaggt
5281 agtcataact atacaatgaa tttggcttct caaaattgga gcaactacga cccaacagaa
5341 gaaatcccag cccctctagg gactccagac tttgtgggga agattcaagg catgctcacc
5401 caaaccacaa ggacagatgg ctcaacacgc ggccacaaag ccacagtgta cactgggagc
5461 gccgactttg ctccaaaact gggtagagtc caatttgaaa ccgacacaaa caatgatttt
5521 gaggctaacc aaaacacaaa gttcacccca gttggtgtca tccaagatgg tggcaccact
5581 catcgaaatg aaccccaaca gtgggtgctc ccaagttact caggcaggaa cactcctaat
5641 gtgcatctgg cccccgctgt ggcccccact tttccgggtg agcaactcct tttctttaga
5701 tccaccatgc ccggttgcag cgggtacccc aacatggatt tggattgtct gctcccccag
5761 gaatgggtgc agtacttcta ccaggaggca gccccagcac aatctgatgt ggctctgcta
5821 agatttgtga atccagacac aggtagggtt ttgtttgaat gtaagcttca taaatcaggc
5881 tatgtcacag tggctcacac tggccaacat gatttggtta ttccccccaa tggttatttt
5941 agatttgatt cctgggtcaa ccagttttac acacttgccc ccatgggaaa tggagcgggg
6001 cgtagacgtg cactataatg gctggagctt tctttgctgg attggcatct gatgttcttg
6061 gctctggact tggttccctt atcaatgctg gggctggggc catcaaccaa aaagttgagt
6121 ttgaaaataa tagaaaattg cagcaagcat ccttccaatt tagcagcaat ctacaacagg
6181 cttcctttca acatgacaaa gagatgctcc aagcacaaat tgaggctacc aaaaggttac
6241 aacgggaaac gatgaaagtt aagcaggcaa tgctcctaga gggtgggttc tctgagacag
6301 atgcagcccg cggggcaatc aacgccccta tgacaaaagc cttggactgg agcgggacaa
6361 ggtactgggc tcctgatgct aggactacaa catacaatgc aggccgcttt tccacccccc
6421 aaccatcagg ggcgttgcca ggaagagcta attttaggga tgctgtccct gctcggggtt
6481 cttctagtaa gtcttctaat tcttctactg ctacttctgt gtattcaaat caaacaactt
6541 caacgagact tggttctaca gctggttctg gtaccagtgt ctcgagcttc ccgtcaactg
6601 caaggactag gagctgggtt gaggaccaaa gtaggaattt gtcacctttc atgagggggg
6661 cccacaacat atcgtttgtc accccaccat ctagcaggtc ctctagccaa ggcacagtct
6721 caaccgtgcc taaagagatt ttggactcct ggactggcgc tttcaacacg cgcaggcagc
6781 cactcttcgc tcacattcgt aagcgagggg agtcacgggt gtaatgtgaa aaggcaaaat
6841 tgattatctt tccttcttta a
//