Typing tool
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Typing tool
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Complete norovirus genomes
| OP805362 | GII.17 | |
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| GII.P17 |
ORF1: 1..5091
ORF2: 5072..6688
ORF3: 6688..7451
LOCUS OP805362 7451 bp RNA linear VRL 24-MAR-2023
DEFINITION Norovirus GII isolate 446222 nonstructural polyprotein (ORF1) gene,
partial cds; VP1 (ORF2) gene, complete cds; and VP2 (ORF3) gene,
partial cds.
ACCESSION OP805362
VERSION OP805362.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7451)
AUTHORS Dinu,S., Oprea,M., Iordache,R.I., Rusu,L.C. and Usein,C.R.
TITLE Genome characterisation of norovirus GII.P17-GII.17 detected during
a large gastroenteritis outbreak in Romania in 2021
JOURNAL Arch Virol 168 (4), 116 (2023)
PUBMED 36947248
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 7451)
AUTHORS Dinu,S., Oprea,M., Iordache,R.I. and Usein,C.R.
TITLE Direct Submission
JOURNAL Submitted (10-NOV-2022) Molecular Epidemiology for Communicable
Diseases Laboratory, Cantacuzino National Military Medical
Institute for Research and Development, 103 Splaiul Independentei,
Bucharest 050096, Romania
COMMENT ##Assembly-Data-START##
Assembly Method :: Bowtie2 v. NOV-2022
Sequencing Technology :: IonTorrent
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7451
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="446222"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Romania"
/collection_date="27-Jul-2021"
/note="genotype: GII.P17-GII.17"
gene <1..5091
/gene="ORF1"
CDS <1..5091
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="UZH91367.1"
/translation="DASVAVAGKNNNNDKEKSSSDSLFSNMTVTFKKALGARSKQPPP
GETKQTQRPPRPPTPELVKKIPPPPPNGEDEPKIAYKVGEGVSGLPDLTTVAQPDAQN
TAYSVPPLSQREAGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAISLAK
IELTPLSLYWRVVYTPQYLIAPETLKNLNGEAFPYTAFDNNCYAFCCWVLDLNDSWLS
RRMIQRTTGFFRPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDVIGKLKP
LNIMNILATCDWTFAGIVESMILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPEDLAV
ELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKWFFPKKE
EANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSSKSA
SPDIVGTVNALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLARELAKK
VASTLSGDQRIGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTCPLT
LNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIEKAKR
DFPGQPDMWKDHYRSDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLIARASGL
LHERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSVKTLDEL
KQAIKNITIKKCQIVYNGCTYTVESDGRNKVVVEKVQNATVQTNNELTGALHHLRSAR
IRYYVKCFQEAIYSLLQIAGAAFVTTRIVRRMNISNLWSKPPVEEGDEPEDKEGCPKP
RDEDDLTIDSKDIKAEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYS
IEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRREERATLGLVTGS
EIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFWVSPSLF
ITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGAPEGTVV
SILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGC
PYIYKRGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGN
APKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGK
PPKPSVLESAKKTIINVLEQTIDPPEKWSYAQACASLDKTTSSGYPHHVRKNDYWSGE
SFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWGSDLSTM
IRCARAFGGLMDELKANCITLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQ
QRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIVINEGLPSGVPCTSQW
NSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLKEYG
LKPTRPDKTEGPLVISEDLNGLTFLRRTITRDPAGWFGKLDQNSILRQLYWTRGPNHE
DPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQESMF
RWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..981
/gene="ORF1"
/product="p48"
mat_peptide 982..2079
/gene="ORF1"
/product="NTPase"
mat_peptide 2080..2616
/gene="ORF1"
/product="p22"
mat_peptide 2617..3015
/gene="ORF1"
/product="VPg"
mat_peptide 3016..3558
/gene="ORF1"
/product="Pro"
mat_peptide 3559..5088
/gene="ORF1"
/product="RdRp"
gene 5072..6688
/gene="ORF2"
CDS 5072..6688
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="UZH91368.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHIIVDVRTLEPIMIPLPD
VRNTFFHYNNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAETDNPDKWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
ASQRNVGNDAPGSTRAHEAVISTYSPRFVPKLGSVNFKSNDNDFQLQPTRFTPVGIND
DGDHPFRQWELPDYSGVLTLNMNLAPPVAPNFPGEQLLLFRSSVPCSGGYNQGIIDCL
IPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVP
ANGYFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6688..>7451
/gene="ORF3"
CDS 6688..>7451
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="UZH91369.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAISQKIDFENNKQLQSA
SFQHDKEMLQAQVNATKQLQSEMIALKQGVLAAGGFSPTDAARGAIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMPSPSAPQSKPAKSRSLGSSSSSSSVYSMSTQST
SLTSGSSSNASSASTKLTNLSSGSSRNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRG"
ORIGIN
1 gacgcttccg tcgccgttgc tggcaaaaac aacaacaacg acaaggaaaa atcttcaagt
61 gacagcttgt tttctaacat gactgttact tttaagaaag ccctcggggc gcggtctaaa
121 cagccgcccc cgggagaaac aaaacaaaca caaagaccac caaggccacc gacaccggaa
181 ttggtgaaga agataccccc accccccccc aatggtgagg atgaaccaaa gatagcgtat
241 aaggtgggag aaggtgtgtc tgggctgccc gacttgacaa ccgtggcaca acctgacgca
301 cagaacacag cctacagtgt ccccccactt agccagagag aggccggcga agctaaagaa
361 ccgttgcctg gctccattct ggaaatgtgg gatggtgaga tctaccacta tgggctgtat
421 gttgagcggg ggcatgtact gggagtgcac aagccacctg ccgcaataag ccttgccaaa
481 attgaattaa caccgctgtc tctctactgg agagtggttt acactcccca atatttgata
541 gctccagaga cccttaagaa tttaaatgga gaggctttcc catacacggc ctttgacaac
601 aactgttatg ccttctgttg ttgggtttta gacctcaacg actcctggct tagcagaaga
661 atgatccaaa gaacaactgg attcttcaga ccgtatcagg actggaacag aaaacccttg
721 ccaaccatgg atgaaccaaa aatcaagaag gccgcgaatg ctgttctgtg tgctctctcc
781 tcactcttca ctaggcccat caaagacgtc attggaaagc tcaaaccact gaacattatg
841 aacatactgg caacttgtga ttggactttt gcgggcatag tggaatccat gatccttctt
901 gctgagctct ttggggtgtt ctggacgccc ccagatgtgt ctgcaatgat tgctccctta
961 ctcggtgact acgagatgca aggccccgaa gacctggccg tggaacttgt gcccgtggta
1021 atgggaggaa taggtttggt gttaggattc accaaggaaa agatcggcaa gatgctttca
1081 tcagctgcga ccacactcag ggcctgtaag gatctaggat cttatgggtt ggagatactc
1141 aaactggtca tgaagtggtt cttccccaag aaggaggagg ccaacgagtt agccatggtg
1201 agggccattg aggatgcagt tctggatttg gaggcaatag aaaacaacca catgaccact
1261 ctccttaagg acaaagacag cctggccaca tacatgagga ctcttgactt ggaagaagaa
1321 aaagcaagga aactgtcatc caaatcggcg tcacctgaca tcgtgggcac agtaaacgca
1381 ttattggcaa ggatagcagc cgccaggtca ctggtccaca aggctaagga ggagctctcg
1441 agcagacaga ggcctgttgt tgtaatgata tcaggtaggc caggtatagg aaagacccat
1501 ctggccagag agctagccaa gaaggttgcg tcaacactgt caggcgacca aaggattgga
1561 ctgataccta gaaatggcgt cgaccattgg gacgcctaca aaggagagcg ggtggttctg
1621 tgggatgact atggcatgag caaccctata caggacgcac tgaggctcca agaattggct
1681 gacacctgtc ctctgaccct aaattgtgac aggattgaaa acaaaggaaa agtgttcgac
1741 agtgacgcca taattataac aaccaacctc gcaaacccag caccactgga ttatgtcaac
1801 tttgaggctt gttctagacg catagacttc ttggtgtatg cagacgcacc tgacatcgag
1861 aaggctaagc gtgacttccc tggccaacca gatatgtgga aagaccatta cagatcagac
1921 ttctcacaca ttaaacttca gctggcacca cagggaggct ttgataagaa tggcaacacc
1981 ccacatggca aaggtgtggt taagtctctg acgattggtt ctctgatcgc cagggcttct
2041 ggcttgctcc atgagagaat ggatgaattt gagctccaag gctctgattt accaaccttc
2101 aatttcgacc gtaacaaagt cgccgccttc agacaattgg cagctgaaaa caaatatggt
2161 cttatggaca cactgagggt cggcaaccaa ctgaaaagtg tcaaaaccct ggatgagctg
2221 aagcaggcta taaagaacat caccatcaag aagtgccaga tagtgtacaa tggatgcacc
2281 tacaccgtgg aatctgatgg gaggaacaag gttgtggttg aaaaggttca aaatgcaaca
2341 gtccaaacca acaatgaact tacaggagca ctccaccacc tgagatctgc aaggataagg
2401 tattatgtta aatgtttcca agaagctatt tactctctac tccaaattgc tggtgcagcc
2461 ttcgtcacca cacgcatcgt gaggcgcatg aacatctcaa acctctggtc gaagccaccc
2521 gtcgaagagg gtgatgagcc tgaagacaaa gaggggtgcc ccaagcccag ggatgaagat
2581 gacctcacta ttgactctaa agacattaaa gcagaaggga agaagggcaa gaacaaatct
2641 ggccggggca agaaacacac agctttctca tccaagggcc tcagtgatga agagtacgat
2701 gagtacaaga gaatcaggga ggagaggaat ggcaaatact caattgaaga atacctccag
2761 gacagggata gatactatga agagcttgcc attgctaagg ccactgagga agacttctgt
2821 gaagaggagg aaatcaaaat tcgccagaga atcttccggc ccaccaggaa gcaacggaga
2881 gaggaaagag ccacgcttgg gcttgtcaca ggatcggaaa tcagaaagag gaacccagat
2941 gactttaagc caaaaggaaa actttgggct gatgacaaca gaagtgtgga ctacaatgag
3001 aggatagatt ttgaggctcc cccgagtgtt tggtctagga tagtcaactt tggtacagga
3061 tggggattct gggtctcccc aagtctcttt ataacttcaa cacatgtcat accaaaagga
3121 atcactgagg cttttggagt tcccattaac caaattcaaa ttcacaaatc tggagagttt
3181 tgccgcttgc ggtttccaaa accaatcagg ccagacgtga gtggaatgat cttggaagag
3241 ggtgcccctg aaggcactgt tgtgtccatt ctcatcaaga ggacaacagg ggaactgatg
3301 cctctcgcag ttagaatggg aactcatgcc acaatgaaaa tccaaggtag aacggtgggt
3361 ggtcaaatgg gcatgcttct cactggctca aacgctaaaa gcatggacct aggcacaaca
3421 ccaggtgact gtgggtgccc atacatatac aaaaggggca atgacttcgt ggtcattggg
3481 gtgcacactg cagcagcccg tggaggcaac acggtcatat gtgccacaca gggaagtgaa
3541 ggcgaagcca ccctcgaagg aggtgacaac aagggcacct attgtggggc ccccatcttg
3601 ggacctggca acgcaccaaa attaagcaca aaaacaaaat tctggagatc ttccaacgcg
3661 ccgcttcctc caggtaccta tgaaccagca taccttggtg gaaaagaccc gcgtgtgaag
3721 ggaggcccat ctctacaaca ggttatgaga gaccaactta aaccttttac agagccaaga
3781 gggaagccac caaaaccaag tgtcctagaa tcagcaaaga agaccatcat taatgttctg
3841 gagcaaacca ttgacccccc tgaaaagtgg tcatatgccc aagcttgtgc atccctcgac
3901 aagacaacct ccagtggata cccgcatcac gtccggaaga atgactattg gagtggtgaa
3961 tccttcacgg ggaaacttgc agaccaggcc tcaaaagcaa accttatgta tgaggaaggc
4021 aagcacatgc aaccagttta caccgcagca ctcaaagacg agctcgtgaa aactgacaaa
4081 atttatggca agatcaagaa aagactcctg tggggctctg acctatctac catgattcga
4141 tgcgccaggg catttggtgg cctcatggat gagctcaaag caaattgtat cacactccct
4201 gtcagagttg gtatgaacat gaatgaagat ggtcccataa tatttgagaa gcactccagg
4261 tacaggtacc actatgatgc tgattactcc cgctgggatt ccacacaaca gcgggcagtg
4321 ctggaagcgg cacttgaaat catggtgaga ttttctgctg agccacagtt ggcacaaata
4381 gtggcagagg acctgctatc accaagtgtg gttgatgtgg gcgatttcaa aattgttatc
4441 aatgaaggcc taccatctgg cgtgccttgc acttcacaat ggaattctat tgcccactgg
4501 ttactcaccc tgtgtgccct gtctgaagta acaggactag gccctgacat catacaagcc
4561 aactccatgt actctttcta tggtgatgat gagattgtga gcacagacat aaaattagac
4621 ccagagaaat tgactgcaaa actcaaagaa tatggtctta aacccacccg gcctgacaag
4681 actgaggggc cactggtaat tagtgaggac ctgaatgggt tgactttcct ccgccgaaca
4741 atcacccgcg atccagcggg ttggtttgga aagttggacc aaaactccat cctcaggcag
4801 ctgtactgga caaggggacc caaccatgaa gaccccagtg agactatgat accacacgca
4861 cagagacctg tgcagctcat ggcactgcta ggagagtcct ccctacatgg accctcattt
4921 tacagcaagg ttagcaagct ggtcatatct gaacttaaag agggaggaat ggatttttat
4981 gtgcccagac aagagtcaat gttcaggtgg atgaggttct cagatctaag cacatgggag
5041 ggcgatcgca atctggctcc cagttttgtg aatgaagatg gcgtcgaatg acgccgctcc
5101 atctaatgat ggtgctgctg gtctcgtacc agagggcaat aacgagaccc ttcccctaga
5161 accagttgcg ggcgcagcta tagccgcacc cgtcactggc caaaacaata taattgaccc
5221 ctggattaga acaaattttg tgcaagcacc aaatggagag ttcacagtgt cacccagaaa
5281 ctctcctgga gaaattttac taaacctaga gttgggccct gatttgaacc cttatttggc
5341 tcatttgtca aggatgtaca atgggtacgc tggtggagtt gaagtccagg ttctcctggc
5401 agggaacgcg ttcactgccg ggaagatcct cttcgccgct gtcccgccaa atttcccagt
5461 ggaattctta agcccagccc agattacaat gctcccacat ataatagtag atgttagaac
5521 tcttgaacca attatgatcc cattacctga tgttaggaac acattcttcc attataacaa
5581 ccagcccaac agccgcatga gattagtggc tatgctctac acccccctta gatctaatgg
5641 ctcaggtgat gatgttttca ctgtttcttg cagggttttg actagaccta ctcctgattt
5701 tgagttcact tacttagtgc caccctctgt tgaatctaag actaagccct tttccttacc
5761 cattttaacc ctttctgagc tcacaaattc gaggttcccg gtccccattg attcgctttt
5821 caccgcccag aacaatgtgt tgcaggtgca gtgtcaaaat ggcaggtgca cacttgacgg
5881 tgagctacaa ggcacaaccc agttgctccc atctggcatc tgtgcgttca gaggacgggt
5941 gacagcagaa actgacaatc ctgataagtg gcacatgcaa ctgcaaaacc tcaatggcac
6001 aacgtatgac ccaactgatg atgtgccagc cccactgggt acacctgact tcaagggcgt
6061 cgtgtttggg atggcaagcc aaagaaatgt gggtaacgat gcgcccggct caaccagggc
6121 tcatgaggcg gtgatttcaa cctacagccc cagatttgtt cccaaattag gctctgtcaa
6181 ttttaaaagt aatgacaatg atttccaatt gcagccaaca agattcacac cagtgggcat
6241 caatgatgat ggcgaccacc cgttcagaca atgggaactg ccagactatt caggggtgct
6301 taccttgaat atgaaccttg cccccccggt tgctccaaat ttccctggtg aacaattatt
6361 actcttcaga tcttccgtgc catgttcagg aggttacaac caaggtatta tagattgtct
6421 tatcccccaa gaatggatcc aacacttcta ccaggaatca gcaccttctc agtcagacgt
6481 ggccctgatc aggtacgtca accccgacac gggtcgcaca ctgtttgagg caaaattgca
6541 cagatctggc tatatcactg tggctcactc tggagactat cctctcgttg ttccggctaa
6601 tggatacttt agatttgact cttgggtaaa tcagttttac tcactcgccc caatgggaac
6661 tgggaatggg cgaaggaggg ctcagtaatg gctggagctt tcattgcagg attggcgggt
6721 gacatgctca cgtcatccgt gggctccctg gtgaacgcag gggcaaacgc catcagccaa
6781 aagatagact ttgaaaacaa caaacaactc cagtctgctt cctttcaaca tgataaagag
6841 atgctccaag cgcaggtaaa tgcaaccaag cagctgcaat ctgagatgat agccctaaaa
6901 cagggggttt tggccgcagg cggcttttcc cccactgatg cagcgagggg ggccatcggt
6961 gcacccatga caaaggtgct tgactggtct ggcactcgat attgggctcc caattccaca
7021 aagacaactg gttattcggg gcaattcacc tcttcacctg tgcacatgcc cagcccgagt
7081 gctccacaat caaaacccgc aaagtccaga tctctaggtt cttcttcttc ttctagtagt
7141 gtttatagta tgtctaccca atcaacttct ctaacatctg gctcttctag taatgcttct
7201 tctgcttcta caaaattgac aaatttaagc tctggctcct ctcgaaacag gacagcagag
7261 tgggtgaacc aacagagaag tctcagccct ttcatgagtg gcgcactcaa tatctcacat
7321 gtcacgccac cttcaagtag ggcctccagt tctgggacgg tctcaaccgt gcccaaggaa
7381 gttttggact cctggacatc tgcattcaac acacgcagac agccgctctt cgcacacctc
7441 agagtgaggg g
//