Typing tool
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Typing tool
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Complete norovirus genomes
| OP805360 | GII.17 | |
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| GII.P17 |
ORF1: 5..5113
ORF2: 5094..6716
ORF3: 6716..7495
LOCUS OP805360 7497 bp RNA linear VRL 24-MAR-2023
DEFINITION Norovirus GII isolate 187601 nonstructural polyprotein (ORF1), VP1
(ORF2), and VP2 (ORF3) genes, complete cds.
ACCESSION OP805360
VERSION OP805360.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7497)
AUTHORS Dinu,S., Oprea,M., Iordache,R.I., Rusu,L.C. and Usein,C.R.
TITLE Genome characterisation of norovirus GII.P17-GII.17 detected during
a large gastroenteritis outbreak in Romania in 2021
JOURNAL Arch Virol 168 (4), 116 (2023)
PUBMED 36947248
REFERENCE 2 (bases 1 to 7497)
AUTHORS Dinu,S., Oprea,M., Iordache,R.I. and Usein,C.R.
TITLE Direct Submission
JOURNAL Submitted (10-NOV-2022) Molecular Epidemiology for Communicable
Diseases Laboratory, Cantacuzino National Military Medical
Institute for Research and Development, 103 Splaiul Independentei,
Bucharest 050096, Romania
COMMENT ##Assembly-Data-START##
Assembly Method :: Bowtie2 v. NOV-2022
Sequencing Technology :: IonTorrent
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7497
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="187601"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Romania"
/collection_date="25-Oct-2015"
/note="genotype: GII.P17-GII.17"
gene 5..5113
/gene="ORF1"
CDS 5..5113
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="UZH91361.1"
/translation="MKMASNDASAAVAGKNNNNDKEKSSSDSLFANMSVTFKKALGAR
SKQPPPGETKQIQKPPRPPTPELVKRIPPPPPNGEDEPGIVYKVGEGVSGLPDLTTVV
QPDAQNTAYSVPPLSQREVGEAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPA
AISLAKIEITPLSLYWRVVYTPQYLIDPGTLKNLSGETFPYTAFDNNCYAFCCWVLDL
NDSWLSRRMIQRTTGFFKPYQDWNRKPLPTMDEPKIKKAANAVLCALSSLFTRPIKDI
IGKLRPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYEMQG
PEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAATTLRACKDLGSYGLEILKLVMKW
FFPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARK
LSTKSASPDIVGTINALLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLA
RELAKKVASTLSGDQRIGLVPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELA
DTCPLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPD
IEKAKRDFPGQPDMWKDHFRPDFSHIKLQLAPQGGFDKNGNTPHGKGVVKSLTIGSLI
ARASGLLHERMDEFELQGSDLPTFNFDRNKVAAFRQLAAENKYGLMDTLRVGNQLKSV
KTLDELKQAIKNISIKKCQIVYNGCTYTMESDGRGKVVVEKVQNATVQTNNELVGALH
HLRSARIRYYVKCFQEAIYSLLQIAGAAFVTSRIVRRMNISNLWSKPPIEEGDEPEDR
EGCPKPRDEDDLTIDSRDIKVEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREE
RNGKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATL
GLVTGSEIRKRNPDDFKPKGKLWADDNRSVDYNERIDFEAPPSVWSRIVNFGTGWGFW
VSPSLFITSTHVIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRPDVSGMILEEGA
PEGTVVSILIKRTTGELMPLAVRMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTT
PGDCGCPYMYKRGNDLVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAP
ILGPGNAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPF
TEPRGKPPNPNVLESAKKTIINVLEQTIDPPQKWSYAQACASLDKTTSSGYPHHVRKN
DYWSGESFTGKLADQASKANLMYEEGKHMQPVYTAALKDELVKTDKIYGKIKKRLLWG
SDLSTMIRCARAFGGLMDEFKANCITLPIRVGMNMNEDGPIIFEKHSRYRYHYDADYS
RWDSTQQRAVLEAALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKIAINEGLPSGV
PCTSQWNSIAHWLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTA
KLKEYGLKPTRPDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQNSILRQLYWT
RGPNHEDPSETMIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVP
RQESMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide 5..1003
/gene="ORF1"
/product="p48"
mat_peptide 1004..2101
/gene="ORF1"
/product="NTPase"
mat_peptide 2102..2638
/gene="ORF1"
/product="p22"
mat_peptide 2639..3037
/gene="ORF1"
/product="VPg"
mat_peptide 3038..3580
/gene="ORF1"
/product="Pro"
mat_peptide 3581..5110
/gene="ORF1"
/product="RdRp"
gene 5094..6716
/gene="ORF2"
CDS 5094..6716
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="UZH91362.1"
/translation="MKMASNDAAPSNDGAAGLVPEGNNETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHLIVDVRTLEPIMIPLPD
VRNTFFHYSNQPNSRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTLSELTNSRFPVPIDSLFTAQNNVLQVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRVTAQINQRDRWHMQLQNLNGTTYDPTDDVPAPLGTPDFKGVVFGM
VSQRNVGNDAPGSTRAQQAWVSTYSPQFVPKLGSVNLRISDNDDFQFQPTKFTPVGVN
DDDDGHPFRQWELPNYSGELTLNMNLAPPVAPNFPGEQLLFFRSFVPCSGGYNQGIID
CLIPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLV
VPANGHFRFDSWVNQFYSLAPMGTGNGRRRAQ"
gene 6716..7495
/gene="ORF3"
CDS 6716..7495
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="UZH91363.1"
/translation="MAGAFIAGLAGDMLTSSVGSLVNAGANAINQKIDFENNKQLQSA
SFQHDKEMLQAQVRATKQLQSEMIALKQGVLAAGGFSPTDAARGSIGAPMTKVLDWSG
TRYWAPNSTKTTGYSGQFTSSPVHMSSPNAPQSKPAKPRSLAPSSSSSSVYSMYTQST
HLTSGSSSNASSASTKLTNLSSGSSQNRTAEWVNQQRSLSPFMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTHRQPLFAHLRVRGESRV"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgcttc cgctgccgtt gctggcaaaa acaacaacaa
61 cgacaaggaa aaatcttcaa gtgacagctt gtttgctaac atgtctgtca cttttaagaa
121 agccctcggg gcgcggtcca aacaaccgcc cccgggagaa acaaaacaaa tacaaaaacc
181 accaaggcca ccgacaccgg aattggtgaa gagaatacct ccacccccac ccaatggcga
241 ggatgaacca gggatagtgt acaaggtggg agagggtgtg tctgggctgc ccgacctaac
301 aactgtggta caacctgacg cacaaaacac agcttatagt gttcccccac ttagccagag
361 agaagtcggc gaagctaaag aaccgctgcc tggctccatt ctggaaatgt gggacggtga
421 gatctaccac tatgggctgt atgttgagcg ggggcatgtg ctcggagtac acaaaccacc
481 tgctgcaata agccttgcca aaattgaaat aacaccgcta tctctctact ggagagtggt
541 ctacactccc cagtatttga tagatccagg aactcttaag aacttgagtg gagagacttt
601 cccatacacg gcctttgaca acaactgcta tgccttctgt tgttgggtcc tagacctcaa
661 cgactcctgg cttagcagga gaatgatcca aagaacaact ggattcttca aaccttatca
721 ggattggaac agaaaaccct taccgaccat ggatgaaccg aaaatcaaga aggccgcgaa
781 tgctgtccta tgcgctctct cctcactctt cactagaccc attaaggaca tcattggaaa
841 gcttagacca ctgaacattc ttaatatact ggcaacctgc gattggactt ttgcaggcat
901 agtggaatcc ttgatccttc ttgctgaact ctttggggtg ttctggacac ccccagatgt
961 gtctgcgatg attgctccct tactcggtga ctacgagatg caaggccccg aagacctggc
1021 cgtggaactt gtgcccgtgg tgatgggagg aataggtttg gtgttaggat tcaccaaaga
1081 aaagatcggc aagatgcttt catcagctgc gaccacactt agggcctgca aggatctagg
1141 atcttatgga ttggagatac tcaaattggt catgaagtgg ttcttcccca agaaggagga
1201 ggctaacgaa ctagccatgg tgagggccat tgaggatgca gtcctggatt tggaggcaat
1261 agaaaacaat cacatgacca cccttctcaa ggataaagac agcctggcca catacatgag
1321 aactcttgac ttggaagaag agaaagcaag gaaactgtca accaaatcgg cgtcacctga
1381 catcgtgggt acaataaacg ctttattggc taggatagca gccgccaggt cactggtcca
1441 caaggctaag gaggagctct cgagcagaca gagacctgtt gttgtaatga tatcaggtag
1501 accaggtata ggaaagactc atctggccag agagctagcc aagaaagttg cgtcaacact
1561 gtcaggcgac caaaggattg gactggtacc tagaaatggc gtcgaccatt gggacgccta
1621 caagggagaa agggtggttc tgtgggatga ttatggtatg agcaacccta tacaggacgc
1681 actgaggctc caagaattgg ctgacacctg tcctctgacc ctaaattgtg ataggattga
1741 aaacaaagga aaagtgttcg acagtgatgc cataattata acaaccaacc ttgcaaaccc
1801 agcaccactg gactatgtca actttgaggc ctgctctaga cgcatagact tcttggtgta
1861 tgcagacgca cctgacattg agaaggctaa gcgtgacttc cctggccaac cagatatgtg
1921 gaaagaccat ttcagaccag acttctcaca catcaaactt cagctggcac cacagggagg
1981 ttttgacaaa aatggcaaca ccccacatgg caaaggtgtg gtgaagtccc tgacgattgg
2041 ttctctgatc gccagggcct ccggcttgct ccacgagaga atggatgaat tcgagctcca
2101 aggctctgac ctgccaacct tcaattttga ccgcaacaaa gtcgccgcct tcagacaatt
2161 agcagctgaa aacaaatatg gtcttatgga cacactgagg gtcggcaacc aactgaaaag
2221 tgttaagacc ctggatgagc tgaagcaggc cataaagaac atcagtatca agaagtgtca
2281 gatagtgtat aatggatgca cctataccat ggaatctgat gggaggggca aggttgtggt
2341 tgaaaaggta caaaacgcaa cagttcaaac caacaacgaa cttgtagggg cgctccacca
2401 cctgagatct gcaaggataa gatactatgt taaatgtttc caagaagcca tttactctct
2461 actccaaatt gctggtgcag ccttcgtcac ctcacgtatc gtgaggcgca tgaacatatc
2521 aaacctctgg tcgaagccac ccatcgagga gggtgatgag cctgaagaca gagaaggatg
2581 ccccaagccc agggatgaag atgacctcac tattgactct agagacatta aagtggaagg
2641 gaagaagggc aagaacaagt ctggccgggg caagaaacac acagccttct cttccaaggg
2701 cctcagtgat gaagagtacg atgagtacaa gagaatcaga gaggagagga atggcaaata
2761 ctcaatagag gaatacctcc aagataggga cagatactat gaagagcttg ccattgctaa
2821 ggccactgag gaggacttct gtgaggagga ggagatcaaa atccgccaga gaatctttcg
2881 acccactagg aagcagcgga aagaggaaag ggccacgctt gggcttgtca caggatcgga
2941 aatcagaaag aggaatccag atgactttaa accaaaagga aaattgtggg ctgatgacaa
3001 caggagcgtg gattacaatg agaggataga ttttgaggct cccccgagtg tttggtctag
3061 gatagtcaac tttggcacag gctggggatt ctgggtctct ccaagtctct ttataacttc
3121 aacacacgtc ataccaaaag gaatcactga ggcctttgga gtgcccataa accaaatcca
3181 aattcacaaa tctggagaat tttgccgctt gcggtttcca aagccaatta gaccagacgt
3241 gagtgggatg atcttggaag agggcgcccc tgaaggcact gttgtgtcta ttctcatcaa
3301 aaggacaaca ggggagctga tgcctcttgc agtcagaatg gggactcatg ccacaatgaa
3361 gatccaaggt agaacggtgg gtggtcagat gggtatgctt ctcactggct caaatgctaa
3421 aagcatggat ctaggcacaa cgccaggtga ctgcggatgt ccatacatgt acaaaagggg
3481 caatgacctt gtggtcattg gggtgcacac tgcagcagct cgtggaggca acacggtcat
3541 atgtgccaca cagggaagtg aaggtgaagc cactcttgaa ggaggtgaca acaagggtac
3601 ctattgtgga gcccctattt tgggacctgg caatgcacca aaattgagta caaagacaaa
3661 attctggaga tcctctaacg caccgcttcc cccaggtact tatgaaccag cataccttgg
3721 tgggagagac ccgcgcgtga agggaggccc atctctgcaa caagttatga gagaccaact
3781 taaacctttt acagagccca gagggaagcc accaaaccca aatgtcttag agtcagcaaa
3841 gaagactatc atcaatgttc tggaacaaac cattgacccc cctcaaaagt ggtcatatgc
3901 ccaagcttgt gcatccctcg acaagacaac ctccagtgga tacccgcacc acgtccggaa
3961 gaatgactat tggagtggcg aatccttcac aggaaaactt gcagatcagg cttcaaaagc
4021 aaatctcatg tatgaggaag gcaagcacat gcaaccagtt tacaccgcag cactcaaaga
4081 cgagctcgtg aaaactgaca aaatttatgg caaaatcaag aaaagactcc tgtggggttc
4141 tgacctctcc acaatgattc gatgcgccag agcatttggt ggtctcatgg atgaattcaa
4201 agcaaattgt attacacttc ctatcagagt tggtatgaat atgaatgaag atggtcccat
4261 aatatttgag aaacactcca ggtacaggta ccactatgat gctgattact cccgctggga
4321 ctccacacaa cagcgagcag tgctggaagc ggcacttgaa atcatggtga gattttctgc
4381 tgagccacag ctggcacaaa tagtggcaga ggacctgctg tcaccaagtg tggttgatgt
4441 gggcgatttc aaaatcgcta tcaatgaagg cctaccatct ggcgtgcctt gcacctcaca
4501 atggaattct attgcccact ggttacttac cttgtgtgcc ctctctgaag tgacaggatt
4561 aggtcctgac atcatacaag ctaactccat gtactctttc tatggtgatg atgagattgt
4621 gagcacagac ataaaattgg acccagagaa attgaccgcc aagctcaaag aatatggcct
4681 taaacccact cggcccgaca aaactgaggg gccgttggtg attagtgagg acctgaatgg
4741 gttgactttc ctccgccgaa cagtcacccg cgatccagca ggttggtttg gaaagttgga
4801 ccaaaactcc atcctcaggc agttgtactg gacaagagga cccaaccatg aagaccccag
4861 tgagaccatg ataccacacg cacaaagacc tgtgcagctc atggcactac taggagaatc
4921 ctccctacat ggaccctcat tttacagcaa ggttagcaaa ttagtcatat ctgaacttaa
4981 agagggagga atggattttt atgtgcccag acaagagtca atgttcagat ggatgaggtt
5041 ctcagatcta agcacatggg agggcgatcg caatctggct cccagttttg tgaatgaaga
5101 tggcgtcgaa tgacgccgct ccatctaatg atggtgctgc tggtctcgta ccagagggca
5161 acaacgagac ccttccccta gaaccagttg cgggcgcagc tatagccgca cccgtcactg
5221 gccaaaacaa cataattgac ccctggatta gaacaaattt tgtgcaagca ccaaatggag
5281 agttcacagt gtcacccaga aactctcctg gagaaatttt attaaactta gagttgggcc
5341 ctgatttgaa cccttatttg gctcatttgt caaggatgta caatgggtat gctggtggag
5401 tggaagttca ggttctcctg gcagggaacg cgttcactgc cggaaagatc ctcttcgccg
5461 ccgtcccgcc aaatttccca gtggaattct taagcccagc ccagatcaca atgctcccac
5521 atttaatagt agatgttagg actcttgaac caattatgat cccactccct gatgttagga
5581 atacattctt ccattatagt aaccagccta acagccgtat gagattagtg gctatgctct
5641 ataccccact cagatctaat ggctcaggtg atgatgtctt tactgtctct tgcagggttt
5701 tgactaggcc tactcctgat tttgagttca cttatttagt gccaccttct gttgaatcta
5761 aaactaagcc tttttcctta cctattttaa ccctttctga gctcacaaat tcgaggttcc
5821 cagtccccat tgattcgctt ttcaccgccc agaataatgt gttgcaggtg cagtgtcaaa
5881 atggcaggtg tacacttgat ggtgagttac aaggcacaac ccagttgctc ccatctggca
5941 tctgtgcatt cagaggacgg gtgacagcac aaattaacca acgtgacagg tggcacatgc
6001 aactgcaaaa ccttaatggt acaacatatg acccaactga tgatgtgccg gccccgctgg
6061 gtacacctga cttcaagggc gtcgtgtttg ggatggtaag ccaaagaaat gtgggtaatg
6121 atgcgcctgg ctcaaccaga gcccaacagg cgtgggtttc aacctatagc ccccaatttg
6181 tccccaaatt aggttctgtc aatcttagaa ttagtgataa tgatgatttc caattccagc
6241 cgacaaaatt cacaccagtg ggcgtcaatg atgacgatga tggccatccg ttcagacaat
6301 gggaactacc aaactattca ggggagctta ccttgaatat gaatcttgcc cccccagttg
6361 ctccaaattt tcctggtgaa caattgttat tcttcagatc tttcgtgcca tgctcaggag
6421 gttacaacca aggtattata gattgtctta ttccccaaga atggatccaa cacttctatc
6481 aggaatcagc accctcccag tcagacgtgg ccctaatcag gtatgtcaac cccgatacgg
6541 gacgtacact gtttgaagca aaattgcaca gatctggtta cattactgtg gctcactctg
6601 gagactatcc tcttgttgtt ccggctaatg gacactttag atttgattct tgggtaaacc
6661 agttttactc actcgcccca atgggaactg ggaatgggcg aaggagggct cagtaatggc
6721 tggggctttc attgcaggat tggcaggcga catgctcacg tcatctgtgg gctcccttgt
6781 gaacgcaggg gcaaacgcca tcaaccaaaa gatagacttt gaaaacaaca aacaactcca
6841 gtctgcttcc tttcagcatg ataaagagat gctccaagcg caggtgaggg caaccaagca
6901 gctgcaatct gaaatgatag ccctaaaaca gggggttttg gccgcaggcg gcttttcccc
6961 cactgatgca gcaaggggat ccattggtgc acccatgaca aaggtgcttg actggtctgg
7021 cactcgatac tgggcgccca attccacaaa gacaactggc tattcgggac aattcacctc
7081 ttcacctgtg catatgtcta gcccaaatgc tccacaatca aaacctgcaa agcctaggtc
7141 tctagctcct tcctcttctt ctagcagtgt ctatagtatg tatactcaat ctactcattt
7201 aacatctggc tcttctagta atgcttcttc tgcctccaca aaattgacaa atttaagctc
7261 tggctcctct caaaacagaa cagcagagtg ggtaaatcaa cagagaagtc ttagcccttt
7321 catgagtggc gcacttaaca tctcacatgt cacgccaccc tcaagtaggg cttccagttc
7381 tgggacggtc tcgaccgtgc ccaaggaagt tttggactcc tggacgtctg cgtttaacac
7441 acacagacag ccgctcttcg cacacctcag agtgaggggg gagtcacgtg tttagtg
//