Typing tool
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Typing tool
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Complete norovirus genomes
| OP727614 | GII.4 Sydney | |
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| GII.P31 |
ORF1: 6..5105
ORF2: 5086..6708
ORF3: 6708..7512
LOCUS OP727614 7512 bp RNA linear VRL 01-NOV-2022
DEFINITION Norovirus GII isolate OES4 nonstructural polyprotein (ORF1) and VP1
(ORF2) genes, complete cds; and VP2 (ORF3) gene, partial cds.
ACCESSION OP727614
VERSION OP727614.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7512)
AUTHORS Kelly,D., Allen,D.J. and Iturriza-Gomara,M.
TITLE Direct Submission
JOURNAL Submitted (27-OCT-2022) Clinical Infection, Microbiology and
Immunity, Institute of Infection and Global Health, 8 West Derby
Street, Liverpool, Please select. L697BE, United Kingdom
COMMENT ##Assembly-Data-START##
Assembly Method :: SPAdes v. 3.15.4
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7512
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="OES4"
/isolation_source="stool sample"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="United Kingdom"
/collection_date="Jan-2017"
/note="genotype: GII.P31/GII.4"
gene 6..5105
/gene="ORF1"
CDS 6..5105
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="UYR40592.1"
/translation="MKMASNDASAAAVANSNNDIAKSSSDGMFSNMAVTFKRALGARP
KQPPPKEIPPRPPRPPTPELVKKIPPPPPNGEDELVVSYSAKDGVSGLPELTTVRQPE
ETNTAFSVPPLNQRESRDAKEPLTGTIIEMWDGEIYHYGLYVERGLILGVHRPPAAIS
LARVELAPLSLFWRPVYTPQYLISPDTLRRLHGESFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGK
LKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPED
LAVELVPIVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINSLLARIAAARSLVHRAKEELSSRPRPVVVMISGRPGIGKTHLAREL
AKKIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEK
AKRDFPGQPDMWKNAFSPDFSHIKLSLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERLDEYELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMRVGKQLKDVKTM
SDLKQALKNIAIKKCQIVYNGGTYTLEADGKGSVKVDKVQSATVQTNNELAGALHHLR
CARIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVEDTEEMANKDGC
LKPKDDEEFVVSSDDIKTEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLNFEAPPSIWSRIVNFGSGWGFWVSP
NLFITSTHVIPQGAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDSKGTYCGAPILG
PGSAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEAAKKTIINVLEQTIDPPQKWSFAQACASLDKTTSSGHPHHMRKNDCW
NGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKVYGKVKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRDVLATALEIMVKFSPEPHLAQIVAEDLLSPSVMDVGDFQISISEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGP
NHEDPFETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide 6..995
/gene="ORF1"
/product="p48"
mat_peptide 996..2093
/gene="ORF1"
/product="NTPase"
mat_peptide 2094..2630
/gene="ORF1"
/product="p22"
mat_peptide 2631..3029
/gene="ORF1"
/product="VPg"
mat_peptide 3030..3572
/gene="ORF1"
/product="Pro"
mat_peptide 3573..5102
/gene="ORF1"
/product="RdRp"
gene 5086..6708
/gene="ORF2"
CDS 5086..6708
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="UYR40593.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHTTGSHNYTMNLASQNWSNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTNHDFEANQNTKFTPVGVIQDG
GTTHRNEPQQWVLPSYSGRNTPNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
gene 6708..>7512
/gene="ORF3"
CDS 6708..>7512
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="UYR40594.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKRLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPRRANLRDTVPTRGSSSKSS
NSSTATSVYSNQTTSTRLGSTAGSGTSVSSFPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 cgtgaatgaa gatggcgtct aacgacgctt ccgctgccgc tgttgccaac agcaacaacg
61 acatcgcaaa atcttcaagt gacggtatgt tttctaacat ggctgtcact tttaagcggg
121 ccctcggggc gcggcctaaa cagccgcccc cgaaggaaat accacccaga cccccgcgac
181 cacccacacc agaattggtc aaaaagatcc ctcctccccc acccaacggg gaggatgaac
241 tagtggtctc ttacagcgcc aaagatggcg tttccggact gcctgagctc accactgtca
301 gacaaccgga agaaaccaac acggcgttca gtgttccccc actcaaccaa agggagagca
361 gggacgccaa ggagccacta actgggacaa ttattgaaat gtgggatgga gaaatctacc
421 attacggcct gtacgtggaa cgaggtctta tacttggtgt gcacaggcca ccggcagcca
481 ttagccttgc tagggtcgag ctagcaccgc tctctttgtt ctggagacct gtatacaccc
541 cccagtatct catctcccca gacactctta ggagattaca tggggagtca ttcccctaca
601 ctgcatttga caacaattgc tacgcctttt gttgctgggt attggaccta aacgactcat
661 ggctaagcag gagaatgatt cagagaacaa caggcttctt caggccgtac caggattgga
721 acaggaaacc cctccccact atggatgatt ccaaattaaa gaaggtagcc aacatattct
781 tgtgcacttt gtcttcacta ttcaccagac ccattaagga cataataggg aagttgaaac
841 ctcttaacat ccttaacatt ctggctacat gtgattggac cttcgcaggc atagtggaat
901 ccttaatact cttggcagaa ctctttggag ttttctggac acccccagat gtgtctgcga
961 tgatcgcccc cttgctaggt gattatgaac tgcaaggacc tgaggacctt gcagtggaac
1021 tggtcccaat agtgatgggg gggataggtt tggtgctagg atttaccaaa gagaaaatcg
1081 gaaagatgct atcatccgct gcatccactt taagagcttg taaagacctt ggtgcatacg
1141 gactggaaat cttaaaattg gtcatgaagt ggttcttccc aaagaaagag gaagcaaatg
1201 aactggctat ggtgagatcc atcgaggatg cagtgttaga cctcgaggca attgaaaaca
1261 accacatgac caccctactc aaagacaaag acagcttggc aacctacatg agaacccttg
1321 accttgagga ggagaaagcc agaaaactct caaccaaatc tgcttcaccc gatattgtgg
1381 gcacaatcaa ctctcttctg gcaagaatcg ctgctgcacg ctccctagtg catcgggcga
1441 aagaagagct ctccagcagg ccgagacctg tcgttgtgat gatatcgggg aggccaggga
1501 tagggaaaac tcaccttgcc agggagctgg ccaagaagat cgcggcctcc ctcacagggg
1561 accagcgtgt gggccttatc ccacgcaatg gtgtcgacca ttgggacgca tacaagggcg
1621 aaagagttgt cctatgggac gactatggaa tgagcaaccc catccacgac gccctcaggt
1681 tgcaggagct tgctgacact tgccccctca cgctaaattg tgacagaatt gagaacaaag
1741 ggaaagtctt tgacagtgat gccataatca tcaccaccaa tctggccaac ccagcaccac
1801 tggattatgt caactttgaa gcgtgctcga gacgtattga tttcctcgtg tacgcagaag
1861 cccctgaggt ggagaaggca aagcgcgact tcccaggtca acctgacatg tggaagaacg
1921 ccttcagtcc tgacttctca cacataaaac tgtcattggc tccacagggt ggttttgaca
1981 agaacggcaa caccccgcat ggaaaagggg tcatgaagac cctcaccact ggctccctca
2041 tcgcccgagc atcagggtta ctccatgaga ggctagatga atatgaactg caaggcccag
2101 ccctcaccac cttcaacttt gaccgcaaca aggtacttgc ttttagacaa cttgctgctg
2161 aaaacaagta tgggctgatg gacacaatga gagttggaaa acagctcaag gatgtcaaga
2221 ccatgtcaga cctcaaacaa gcactcaaga acatcgcgat caagaagtgc cagatagtgt
2281 acaatggtgg cacctacaca cttgaggctg atggcaaggg tagtgtgaaa gttgacaaag
2341 tgcaaagtgc cactgtgcag accaacaatg aactagccgg tgccctacac cacctaaggt
2401 gcgctagaat cagatactat gtcaagtgcg tccaggaggc actgtattcc atcatccaaa
2461 tcgctggggc tgcattcgtc accacgcgca tcgctaagcg catgaatata caaaatctct
2521 ggtccaagcc acaggtggaa gacacagaag agatggccaa caaagatggt tgcctaaaac
2581 ccaaagatga tgaggagttt gtcgtctcat ccgacgacat caaaactgag ggcaagaaag
2641 ggaagaacaa gtctggccgt ggcaagaagc acacagcctt ttcaagtaaa gggctcagtg
2701 atgaggagta cgatgagtac aagagaatca gagaagaaag gaatggtaag tactccatag
2761 aagagtacct tcaggacaga gacaggtact acgaggaggt ggccattgcc agggcaaccg
2821 aagaggactt ctgtgaagaa gaagaggcca aaatccggca gagaattttc agaccaacaa
2881 ggaaacaacg caaagaagag agggcctctc tcggcttggt cacaggctct gaaatcagga
2941 aaagaaaccc agaagacttc aaacccaagg gaaagctgtg ggctgatgat gacagaagtg
3001 ttgactacaa tgagaaactc aactttgagg ccccaccaag catctggtcg cggatagtca
3061 actttggttc gggctggggc ttctgggtct cccccaatct gtttataaca tcaacccatg
3121 tcatacccca aggtgcaaaa gagttcttcg gagtccctat caagcaaatc caaatacaca
3181 agtcaggtga attctgccgg ttgagattcc caaagccaat cagaactgat gtgactggca
3241 tgattctaga agaaggtgcg cccgagggga ccgtggccac actgctcatc aagagaccaa
3301 ctggagagct catgcctctg gcagccagaa tggggaccca tgcaaccatg aaaattcagg
3361 ggcgcacagt tggagggcaa atgggtatgc tcctgacagg atccaacgcc aagagtatgg
3421 acctaggcac aacaccaggc gactgcggct gcccctacat ctacaagagg gggaatgact
3481 acgtggtcat aggagtccat acggccgctg cccgtggagg aaacactgtc atatgtgcca
3541 cccaggggag tgagggagaa gccacacttg aaggaggtga cagtaaaggg acatactgtg
3601 gcgcaccaat cttgggccca gggagcgctc cgaagctcag caccaagact aagttttgga
3661 gatcatccac aacaccactc ccacctggca cctacgaacc agcctacctc ggtggcaagg
3721 accctagagt caaaggtggc ccttcattgc aacaagttat gagggaccag ctgaagccat
3781 tcacagagcc cagaggcaaa ccaccaagac caagtgtgct ggaggctgcc aagaaaacca
3841 tcatcaatgt ccttgagcaa acaattgatc caccccaaaa atggtcattt gcgcaagctt
3901 gcgcatccct tgacaaaacc acctccagcg gccacccgca ccacatgcgg aaaaacgact
3961 gttggaatgg ggagtccttc acaggaaaat tggctgatca agcctccaag gccaacctaa
4021 tgtttgagga gggaaagaac atgactccag tctacacagg tgcacttaaa gatgagttgg
4081 taaagaccga taaagtttat ggtaaggtca agaagaggct tctgtggggt tcagatctag
4141 cgaccatgat acggtgcgcc cgagcttttg gaggccttat ggatgaactc aaggcacact
4201 gtgtcacact tcctgtcaga gttggtatga acatgaatga ggatggcccc atcatctttg
4261 agaagcactc cagatataga tatcactatg atgctgatta ctcccggtgg gactcaacac
4321 agcaaaggga tgtgctagca acagcactag aaatcatggt taagttctct ccagaaccac
4381 acctggccca aatagttgca gaagacctcc tttcccctag cgtgatggat gtaggtgact
4441 ttcaaatatc aataagtgag ggtctcccct ctggggtacc ttgtacctcc cagtggaatt
4501 ccatcgccca ctggctcctc actctgtgtg cactctctga agtcacggac ctatcccctg
4561 atattattca ggccaactcc cttttctcct tctatggtga tgatgagatt gtaagcacag
4621 atataaagtt ggacccagag aagctgacag caaaactcaa ggagtacggg ctgaaaccaa
4681 cccgccctga caaaactgaa ggaccccttg ttatctctga agacctggat ggcttgacat
4741 tcctccggag aactgtgacc cgtgatccag ctggctggtt tggaaaatta gaacaaagtt
4801 caattctcag gcaaatgtac tggaccaggg gtcctaacca tgaagaccca tttgaaacaa
4861 tgataccaca ctcccaaaga cccatacaat tgatgtcctt gctgggcgag gctgcactcc
4921 acggcccggc attctatagc aaaattagca aattagtcat tgcagagttg aaggagggtg
4981 gcatggattt ttacgtaccc agacaagagc caatgttcag atggatgaga ttctcagatc
5041 tgagcacgtg ggagggcgat cgcaatctgg ctcccagttt tgtgaatgaa gatggcgtcg
5101 agtgacgcca acccatctga tgggtccgca gccaacctcg tcccagaggt caacaatgag
5161 gttatggctc tggagcccgt tgttggtgcc gccattgcgg cacctgtagc gggccaacaa
5221 aatgtaattg acccctggat tagaaataat tttgtacaag cccctggtgg agagttcaca
5281 gtatccccta gaaacgctcc aggtgaaata ctatggagcg cgcccctggg ccctgatcta
5341 aatccctacc tatcccattt ggccagaatg tacaatggtt atgcaggtgg ttttgaagtg
5401 caggtaattc tcgcggggaa cgcgttcacc gccgggaagg tcatatttgc agcagttcca
5461 ccaaattttc caactgaagg cttgagcccc agccaggtca ctatgtttcc ccatatagta
5521 gtggatgtta ggcaattaga acctgtgttg attcccttac ccgatgttag gaataatttc
5581 tatcattaca atcaatcaaa tgaccccacc attaagttga tagcaatgtt gtatacacca
5641 cttagggcta ataatgctgg ggatgatgtc ttcacagttt cctgccgagt tctcacgaga
5701 ccatcccccg attttgattt catattccta gtgccaccca cagttgagtc aagaactaaa
5761 ccattctctg tcccagtttt aactgttgag gagatgacca attcaagatt ccccattcct
5821 ttggaaaagt tgttcacggg tcccagcagt gcctttgttg tccaaccaca aaacggcagg
5881 tgcacgactg atggcgtgct cctaggcacc acccaactgt ctcctgtcaa catctgcacc
5941 ttcagaggag atgtcaccca taccacaggt agtcataact acacaatgaa tttggcttct
6001 caaaattgga gcaattatga cccaacagaa gaaatcccag cccctctagg aactccagat
6061 tttgtgggga agattcaggg cgtgctcacc caaaccacaa ggacagatgg ctcaacacgc
6121 ggccacaaag ccacagtgta tactgggagc gccgactttg ctccaaaact gggtagagtt
6181 caatttgaaa ctgacacaaa ccatgatttt gaagctaacc aaaacacaaa gttcacccca
6241 gttggtgtca tccaagatgg tggcaccacc caccgaaatg agccccaaca gtgggtgctc
6301 ccaagttact caggcaggaa cactcccaat gtgcatctgg cccccgctgt agcccccact
6361 tttccgggtg agcaacttct cttcttcaga tccaccatgc ccggatgcag cgggtacccc
6421 aacatggatt tggactgtct gctcccccag gaatgggtgc agtacttcta ccaagaggcg
6481 gccccagcac aatctgatgt ggctctgcta agatttgtga atccagacac aggtagggtt
6541 ttgtttgagt gtaagcttca taaatcaggc tatgttacag tggctcacac tggccaacat
6601 gatttggtta ttccccccaa tggttatttt aggtttgatt cctgggtcaa ccagttctac
6661 acgcttgccc ccatgggaaa tggaacgggg cgtagacgtg cactataatg gctggagctt
6721 tctttgctgg attggcatct gatgtccttg gctctggact tggttccctt atcaatgctg
6781 gggctggggc cattaaccaa aaagttgagt ttgaaaataa cagaaaattg caacaagcat
6841 ccttccaatt tagcagcaat ctacaacagg cttcctttca acatgacaaa gagatgctcc
6901 aagcacaaat tgaggccacc aaaaggctac aacaggaaat gatgaaagtt aagcaggcaa
6961 tgctcctgga gggtggattc tctgagacag atgcagctcg cggggcaatc aacgccccca
7021 tgacaaaagc tttggactgg agcgggacaa ggtactgggc tcccgacgct aggactacaa
7081 catacaatgc aggccgcttt tccacccctc aaccatcggg ggcactgcca agaagagcta
7141 atctcaggga tactgtccct actcggggtt cctccagtaa gtcttctaat tcttctactg
7201 ctacttctgt gtactcaaat caaaccactt caacgagact tggttctaca gctggttctg
7261 gcaccagtgt ctcgagcttc ccgtcaactg caaggactag gagctgggtt gaggatcaaa
7321 acaggaattt gtcacctttc atgagggggg cccacaacat atcgtttgtc accccaccat
7381 ctagcagatc ctctagccaa ggcacagtct caaccgtgcc taaagagatt ttggactcct
7441 ggactggcgc tttcaacacg cgcaggcagc cactcttcgc tcacattcgt aagcgagggg
7501 agtcacgggc gt
//