Typing tool
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Typing tool
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Complete norovirus genomes
| OP727613 | GII.4 Sydney | |
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| GII.P31 |
ORF1: 7..5106
ORF2: 5087..6709
ORF3: 6709..7513
LOCUS OP727613 7513 bp RNA linear VRL 01-NOV-2022
DEFINITION Norovirus GII isolate OES3 nonstructural polyprotein (ORF1) and VP1
(ORF2) genes, complete cds; and VP2 (ORF3) gene, partial cds.
ACCESSION OP727613
VERSION OP727613.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7513)
AUTHORS Kelly,D., Allen,D.J. and Iturriza-Gomara,M.
TITLE Direct Submission
JOURNAL Submitted (27-OCT-2022) Clinical Infection, Microbiology and
Immunity, Institute of Infection and Global Health, 8 West Derby
Street, Liverpool, Please select. L697BE, United Kingdom
COMMENT ##Assembly-Data-START##
Assembly Method :: SPAdes v. 3.15.4
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7513
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="OES3"
/isolation_source="stool sample"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="United Kingdom"
/collection_date="Jan-2017"
/note="genotype: GII.P31/GII.4"
gene 7..5106
/gene="ORF1"
CDS 7..5106
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="UYR40589.1"
/translation="MKMASNDASAAAVANSNNDIAKSSSDGMFSNMAVTFKRALGARP
KQPPPKEIPPRPPRPPTPELVKKIPPPPPNGEDELVVSYSAKDGVSGLPELTTVRQPE
ETNTAFSVPPLNQRESRDAKEPLTGTIIEMWDGEIYHYGLYVERGLILGVHRPPAAIS
LARVELAPLSLFWRPVYTPQYLISPDTLRRLHGESFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGK
LKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPED
LAVELVPIVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINSLLARIAAARSLVHRAKEELSSRPRPVVVMISGRPGIGKTHLAREL
AKKIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEK
AKRDFPGQPDMWKNAFSPDFSHIKLSLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERLDEYELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMRVGKQLKDVKTM
SDLKQALKNIAIKKCQIVYNGGTYTLEADGKGSVKVDKVQSATVQTNNELAGALHHLR
CARIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVEDTEEMANKDGC
LKPKDDEEFVVSSDDIKTEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLNFEAPPSIWSRIVNFGSGWGFWVSP
NLFITSTHVIPQGAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDSKGTYCGAPILG
PGSAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEAAKKTIINVLEQTIDPPQKWSFAQACASLDKTTSSGHPHHMRKNDCW
NGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKVYGKVKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRDVLATALEIMVKFSPEPHLAQIVAEDLLSPSVMDVGDFQISISEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGP
NHEDPFETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide 7..996
/gene="ORF1"
/product="p48"
mat_peptide 997..2094
/gene="ORF1"
/product="NTPase"
mat_peptide 2095..2631
/gene="ORF1"
/product="p22"
mat_peptide 2632..3030
/gene="ORF1"
/product="VPg"
mat_peptide 3031..3573
/gene="ORF1"
/product="Pro"
mat_peptide 3574..5103
/gene="ORF1"
/product="RdRp"
gene 5087..6709
/gene="ORF2"
CDS 5087..6709
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="UYR40590.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHTTGSHNYTMNLASQNWSNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTNHDFEANQNTKFTPVGVIQDG
GTTHRNEPQQWVLPSYSGRNTPNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
gene 6709..>7513
/gene="ORF3"
CDS 6709..>7513
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="UYR40591.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKRLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPRRANLRDTVPTRGSSSKSS
NSSTATSVYSNQTTSTRLGSTAGSGTSVSSFPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 ttgtgaatga agatggcgtc taacgacgct tccgctgccg ctgttgccaa cagcaacaac
61 gacatcgcaa aatcttcaag tgacggtatg ttttctaaca tggctgtcac ttttaagcgg
121 gccctcgggg cgcggcctaa acagccgccc ccgaaggaaa taccacccag acccccgcga
181 ccacccacac cagaattggt caaaaagatc cctcctcccc cacccaacgg ggaggatgaa
241 ctagtggtct cttacagcgc caaagatggc gtttccggac tgcctgagct caccactgtc
301 agacaaccgg aagaaaccaa cacggcgttc agtgttcccc cactcaacca aagggagagc
361 agggacgcca aggagccact aactgggaca attattgaaa tgtgggatgg agaaatctac
421 cattacggcc tgtacgtgga acgaggtctt atacttggtg tgcacaggcc accggcagcc
481 attagccttg ctagggtcga gctagcaccg ctctctttgt tctggagacc tgtatacacc
541 ccccagtatc tcatctcccc agacactctt aggagattac atggggagtc attcccctac
601 actgcatttg acaacaattg ctacgccttt tgttgctggg tattggacct aaacgactca
661 tggctaagca ggagaatgat tcagagaaca acaggcttct tcaggccgta ccaggattgg
721 aacaggaaac ccctccccac tatggatgat tccaaattaa agaaggtagc caacatattc
781 ttgtgcactt tgtcttcact attcaccaga cccattaagg acataatagg gaagttgaaa
841 cctcttaaca tccttaacat tctggctaca tgtgattgga ccttcgcagg catagtggaa
901 tccttaatac tcttggcaga actctttgga gttttctgga cacccccaga tgtgtctgcg
961 atgatcgccc ccttgctagg tgattatgaa ctgcaaggac ctgaggacct tgcagtggaa
1021 ctggtcccaa tagtgatggg ggggataggt ttggtgctag gatttaccaa agagaaaatc
1081 ggaaagatgc tatcatccgc tgcatccact ttaagagctt gtaaagacct tggtgcatac
1141 ggactggaaa tcttaaaatt ggtcatgaag tggttcttcc caaagaaaga ggaagcaaat
1201 gaactggcta tggtgagatc catcgaggat gcagtgttag acctcgaggc aattgaaaac
1261 aaccacatga ccaccctact caaagacaaa gacagcttgg caacctacat gagaaccctt
1321 gaccttgagg aggagaaagc cagaaaactc tcaaccaaat ctgcttcacc cgatattgtg
1381 ggcacaatca actctcttct ggcaagaatc gctgctgcac gctccctagt gcatcgggcg
1441 aaagaagagc tctccagcag gccgagacct gtcgttgtga tgatatcggg gaggccaggg
1501 atagggaaaa ctcaccttgc cagggagctg gccaagaaga tcgcggcctc cctcacaggg
1561 gaccagcgtg tgggccttat cccacgcaat ggtgtcgacc attgggacgc atacaagggc
1621 gaaagagttg tcctatggga cgactatgga atgagcaacc ccatccacga cgccctcagg
1681 ttgcaggagc ttgctgacac ttgccccctc acgctaaatt gtgacagaat tgagaacaaa
1741 gggaaagtct ttgacagtga tgccataatc atcaccacca atctggccaa cccagcacca
1801 ctggattatg tcaactttga agcgtgctcg agacgtattg atttcctcgt gtacgcagaa
1861 gcccctgagg tggagaaggc aaagcgcgac ttcccaggtc aacctgacat gtggaagaac
1921 gccttcagtc ctgacttctc acacataaaa ctgtcattgg ctccacaggg tggttttgac
1981 aagaacggca acaccccgca tggaaaaggg gtcatgaaga ccctcaccac tggctccctc
2041 atcgcccgag catcagggtt actccatgag aggctagatg aatatgaact gcaaggccca
2101 gccctcacca ccttcaactt tgaccgcaac aaggtacttg cttttagaca acttgctgct
2161 gaaaacaagt atgggctgat ggacacaatg agagttggaa aacagctcaa ggatgtcaag
2221 accatgtcag acctcaaaca agcactcaag aacatcgcga tcaagaagtg ccagatagtg
2281 tacaatggtg gcacctacac acttgaggct gatggcaagg gtagtgtgaa agttgacaaa
2341 gtgcaaagtg ccactgtgca gaccaacaat gaactagccg gtgccctaca ccacctaagg
2401 tgcgctagaa tcagatacta tgtcaagtgc gtccaggagg cactgtattc catcatccaa
2461 atcgctgggg ctgcattcgt caccacgcgc atcgctaagc gcatgaatat acaaaatctc
2521 tggtccaagc cacaggtgga agacacagaa gagatggcca acaaagatgg ttgcctaaaa
2581 cccaaagatg atgaggagtt tgtcgtctca tccgacgaca tcaaaactga gggcaagaaa
2641 gggaagaaca agtctggccg tggcaagaag cacacagcct tttcaagtaa agggctcagt
2701 gatgaggagt acgatgagta caagagaatc agagaagaaa ggaatggtaa gtactccata
2761 gaagagtacc ttcaggacag agacaggtac tacgaggagg tggccattgc cagggcaacc
2821 gaagaggact tctgtgaaga agaagaggcc aaaatccggc agagaatttt cagaccaaca
2881 aggaaacaac gcaaagaaga gagggcctct ctcggcttgg tcacaggctc tgaaatcagg
2941 aaaagaaacc cagaagactt caaacccaag ggaaagctgt gggctgatga tgacagaagt
3001 gttgactaca atgagaaact caactttgag gccccaccaa gcatctggtc gcggatagtc
3061 aactttggtt cgggctgggg cttctgggtc tcccccaatc tgtttataac atcaacccat
3121 gtcatacccc aaggtgcaaa agagttcttc ggagtcccta tcaagcaaat ccaaatacac
3181 aagtcaggtg aattctgccg gttgagattc ccaaagccaa tcagaactga tgtgactggc
3241 atgattctag aagaaggtgc gcccgagggg accgtggcca cactgctcat caagagacca
3301 actggagagc tcatgcctct ggcagccaga atggggaccc atgcaaccat gaaaattcag
3361 gggcgcacag ttggagggca aatgggtatg ctcctgacag gatccaacgc caagagtatg
3421 gacctaggca caacaccagg cgactgcggc tgcccctaca tctacaagag ggggaatgac
3481 tacgtggtca taggagtcca tacggccgct gcccgtggag gaaacactgt catatgtgcc
3541 acccagggga gtgagggaga agccacactt gaaggaggtg acagtaaagg gacatactgt
3601 ggcgcaccaa tcttgggccc agggagcgct ccgaagctca gcaccaagac taagttttgg
3661 agatcatcca caacaccact cccacctggc acctacgaac cagcctacct cggtggcaag
3721 gaccctagag tcaaaggtgg cccttcattg caacaagtta tgagggacca gctgaagcca
3781 ttcacagagc ccagaggcaa accaccaaga ccaagtgtgc tggaggctgc caagaaaacc
3841 atcatcaatg tccttgagca aacaattgat ccaccccaaa aatggtcatt tgcgcaagct
3901 tgcgcatccc ttgacaaaac cacctccagc ggccacccgc accacatgcg gaaaaacgac
3961 tgttggaatg gggagtcctt cacaggaaaa ttggctgatc aagcctccaa ggccaaccta
4021 atgtttgagg agggaaagaa catgactcca gtctacacag gtgcacttaa agatgagttg
4081 gtaaagaccg ataaagttta tggtaaggtc aagaagaggc ttctgtgggg ttcagatcta
4141 gcgaccatga tacggtgcgc ccgagctttt ggaggcctta tggatgaact caaggcacac
4201 tgtgtcacac ttcctgtcag agttggtatg aacatgaatg aggatggccc catcatcttt
4261 gagaagcact ccagatatag atatcactat gatgctgatt actcccggtg ggactcaaca
4321 cagcaaaggg atgtgctagc aacagcacta gaaatcatgg ttaagttctc tccagaacca
4381 cacctggccc aaatagttgc agaagacctc ctttccccta gcgtgatgga tgtaggtgac
4441 tttcaaatat caataagtga gggtctcccc tctggggtac cttgtacctc ccagtggaat
4501 tccatcgccc actggctcct cactctgtgt gcactctctg aagtcacgga cctatcccct
4561 gatattattc aggccaactc ccttttctcc ttctatggtg atgatgagat tgtaagcaca
4621 gatataaagt tggacccaga gaagctgaca gcaaaactca aggagtacgg gctgaaacca
4681 acccgccctg acaaaactga aggacccctt gttatctctg aagacctgga tggcttgaca
4741 ttcctccgga gaactgtgac ccgtgatcca gctggctggt ttggaaaatt agaacaaagt
4801 tcaattctca ggcaaatgta ctggaccagg ggtcctaacc atgaagaccc atttgaaaca
4861 atgataccac actcccaaag acccatacaa ttgatgtcct tgctgggcga ggctgcactc
4921 cacggcccgg cattctatag caaaattagc aaattagtca ttgcagagtt gaaggagggt
4981 ggcatggatt tttacgtacc cagacaagag ccaatgttca gatggatgag attctcagat
5041 ctgagcacgt gggagggcga tcgcaatctg gctcccagtt ttgtgaatga agatggcgtc
5101 gagtgacgcc aacccatctg atgggtccgc agccaacctc gtcccagagg tcaacaatga
5161 ggttatggct ctggagcccg ttgttggtgc cgccattgcg gcacctgtag cgggccaaca
5221 aaatgtaatt gacccctgga ttagaaataa ttttgtacaa gcccctggtg gagagttcac
5281 agtatcccct agaaacgctc caggtgaaat actatggagc gcgcccctgg gccctgatct
5341 aaatccctac ctatcccatt tggccagaat gtacaatggt tatgcaggtg gttttgaagt
5401 gcaggtaatt ctcgcgggga acgcgttcac cgccgggaag gtcatatttg cagcagttcc
5461 accaaatttt ccaactgaag gcttgagccc cagccaggtc actatgtttc cccatatagt
5521 agtggatgtt aggcaattag aacctgtgtt gattccctta cccgatgtta ggaataattt
5581 ctatcattac aatcaatcaa atgaccccac cattaagttg atagcaatgt tgtatacacc
5641 acttagggct aataatgctg gggatgatgt cttcacagtt tcctgccgag ttctcacgag
5701 accatccccc gattttgatt tcatattcct agtgccaccc acagttgagt caagaactaa
5761 accattctct gtcccagttt taactgttga ggagatgacc aattcaagat tccccattcc
5821 tttggaaaag ttgttcacgg gtcccagcag tgcctttgtt gtccaaccac aaaacggcag
5881 gtgcacgact gatggcgtgc tcctaggcac cacccaactg tctcctgtca acatctgcac
5941 cttcagagga gatgtcaccc ataccacagg tagtcataac tacacaatga atttggcttc
6001 tcaaaattgg agcaattatg acccaacaga agaaatccca gcccctctag gaactccaga
6061 ttttgtgggg aagattcagg gcgtgctcac ccaaaccaca aggacagatg gctcaacacg
6121 cggccacaaa gccacagtgt atactgggag cgccgacttt gctccaaaac tgggtagagt
6181 tcaatttgaa actgacacaa accatgattt tgaagctaac caaaacacaa agttcacccc
6241 agttggtgtc atccaagatg gtggcaccac ccaccgaaat gagccccaac agtgggtgct
6301 cccaagttac tcaggcagga acactcccaa tgtgcatctg gcccccgctg tagcccccac
6361 ttttccgggt gagcaacttc tcttcttcag atccaccatg cccggatgca gcgggtaccc
6421 caacatggat ttggactgtc tgctccccca ggaatgggtg cagtacttct accaagaggc
6481 ggccccagca caatctgatg tggctctgct aagatttgtg aatccagaca caggtagggt
6541 tttgtttgag tgtaagcttc ataaatcagg ctatgttaca gtggctcaca ctggccaaca
6601 tgatttggtt attcccccca atggttattt taggtttgat tcctgggtca accagttcta
6661 cacgcttgcc cccatgggaa atggaacggg gcgtagacgt gcactataat ggctggagct
6721 ttctttgctg gattggcatc tgatgtcctt ggctctggac ttggttccct tatcaatgct
6781 ggggctgggg ccattaacca aaaagttgag tttgaaaata acagaaaatt gcaacaagca
6841 tccttccaat ttagcagcaa tctacaacag gcttcctttc aacatgacaa agagatgctc
6901 caagcacaaa ttgaggccac caaaaggcta caacaggaaa tgatgaaagt taagcaggca
6961 atgctcctgg agggtggatt ctctgagaca gatgcagctc gcggggcaat caacgccccc
7021 atgacaaaag ctttggactg gagcgggaca aggtactggg ctcccgacgc taggactaca
7081 acatacaatg caggccgctt ttccacccct caaccatcgg gggcactgcc aagaagagct
7141 aatctcaggg atactgtccc tactcggggt tcctccagta agtcttctaa ttcttctact
7201 gctacttctg tgtactcaaa tcaaaccact tcaacgagac ttggttctac agctggttct
7261 ggcaccagtg tctcgagctt cccgtcaact gcaaggacta ggagctgggt tgaggatcaa
7321 aacaggaatt tgtcaccttt catgaggggg gcccacaaca tatcgtttgt caccccacca
7381 tctagcagat cctctagcca aggcacagtc tcaaccgtgc ctaaagagat tttggactcc
7441 tggactggcg ctttcaacac gcgcaggcag ccactcttcg ctcacattcg taagcgaggg
7501 gagtcacggg cgt
//