Typing tool
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Typing tool
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Complete norovirus genomes
| OP727612 | GII.4 Sydney | |
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| GII.P31 |
ORF1: 8..5107
ORF2: 5088..6710
ORF3: 6710..7514
LOCUS OP727612 7514 bp RNA linear VRL 01-NOV-2022
DEFINITION Norovirus GII isolate OES1 nonstructural polyprotein (ORF1) and VP1
(ORF2) genes, complete cds; and VP2 (ORF3) gene, partial cds.
ACCESSION OP727612
VERSION OP727612.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7514)
AUTHORS Kelly,D., Allen,D.J. and Iturriza-Gomara,M.
TITLE Direct Submission
JOURNAL Submitted (27-OCT-2022) Clinical Infection, Microbiology and
Immunity, Institute of Infection and Global Health, 8 West Derby
Street, Liverpool, Please select. L697BE, United Kingdom
COMMENT ##Assembly-Data-START##
Assembly Method :: SPAdes v. 3.15.4
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7514
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="OES1"
/isolation_source="stool sample"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="United Kingdom"
/collection_date="Jan-2017"
/note="genotype: GII.P31/GII.4"
gene 8..5107
/gene="ORF1"
CDS 8..5107
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="UYR40586.1"
/translation="MKMASNDASAAAVANSNNDIAKSSSDGMFSNMAVTFKRALGARP
KQPPPKEIPPRPPRPPTPELVKKIPPPPPNGEDELVVSYSAKDGVSGLPELTTVRQPE
ETNTAFSVPPLNQRESRDAKEPLTGTIIEMWDGEIYHYGLYVERGLILGVHRPPAAIS
LARVELAPLSLFWRPVYTPQYLISPDTLRRLHGESFPYTAFDNNCYAFCCWVLDLNDS
WLSRRMIQRTTGFFRPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGK
LKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPED
LAVELVPIVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFP
KKEEANELAMVRSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLST
KSASPDIVGTINSLLARIAAARSLVHRAKEELSSRPRPVVVMISGRPGIGKTHLAREL
AKKIAASLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTC
PLTLNCDRIENKGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEK
AKRDFPGQPDMWKNAFSPDFSHIKLSLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARA
SGLLHERLDEYELQGPALTTFNFDRNKVLAFRQLAAENKYGLMDTMRVGKQLKDVKTM
SDLKQALKNIAIKKCQIVYNGGTYTLEADGKGSVKVDKVQSATVQTNNELAGALHHLR
CARIRYYVKCVQEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVEDTEEMANKDGC
LKPKDDEEFVVSSDDIKTEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLV
TGSEIRKRNPEDFKPKGKLWADDDRSVDYNEKLNFEAPPSIWSRIVNFGSGWGFWVSP
NLFITSTHVIPQGAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEG
TVATLLIKRPTGELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGD
CGCPYIYKRGNDYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDSKGTYCGAPILG
PGSAPKLSTKTKFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEAAKKTIINVLEQTIDPPQKWSFAQACASLDKTTSSGHPHHMRKNDCW
NGESFTGKLADQASKANLMFEEGKNMTPVYTGALKDELVKTDKVYGKVKKRLLWGSDL
ATMIRCARAFGGLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWD
STQQRDVLATALEIMVKFSPEPHLAQIVAEDLLSPSVMDVGDFQISISEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLK
EYGLKPTRPDKTEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGP
NHEDPFETMIPHSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide 8..997
/gene="ORF1"
/product="p48"
mat_peptide 998..2095
/gene="ORF1"
/product="NTPase"
mat_peptide 2096..2632
/gene="ORF1"
/product="p22"
mat_peptide 2633..3031
/gene="ORF1"
/product="VPg"
mat_peptide 3032..3574
/gene="ORF1"
/product="Pro"
mat_peptide 3575..5104
/gene="ORF1"
/product="RdRp"
gene 5088..6710
/gene="ORF2"
CDS 5088..6710
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="UYR40587.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHTTGSHNYTMNLASQNWSNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTNHDFEANQNTKFTPVGVIQDG
GTTHRNEPQQWVLPSYSGRNTPNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAL"
gene 6710..>7514
/gene="ORF3"
CDS 6710..>7514
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="UYR40588.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKRLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGALPRRANLRDTVPTRGSSSKSS
NSSTATSVYSNQTTSTRLGSTAGSGTSVSSFPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 tctgtgaatg aagatggcgt ctaacgacgc ttccgctgcc gctgttgcca acagcaacaa
61 cgacatcgca aaatcttcaa gtgacggtat gttttctaac atggctgtca cttttaagcg
121 ggccctcggg gcgcggccta aacagccgcc cccgaaggaa ataccaccca gacccccgcg
181 accacccaca ccagaattgg tcaaaaagat ccctcctccc ccacccaacg gggaggatga
241 actagtggtc tcttacagcg ccaaagatgg cgtttccgga ctgcctgagc tcaccactgt
301 cagacaaccg gaagaaacca acacggcgtt cagtgttccc ccactcaacc aaagggagag
361 cagggacgcc aaggagccac taactgggac aattattgaa atgtgggatg gagaaatcta
421 ccattacggc ctgtacgtgg aacgaggtct tatacttggt gtgcacaggc caccggcagc
481 cattagcctt gctagggtcg agctagcacc gctctctttg ttctggagac ctgtatacac
541 cccccagtat ctcatctccc cagacactct taggagatta catggggagt cattccccta
601 cactgcattt gacaacaatt gctacgcctt ttgttgctgg gtattggacc taaacgactc
661 atggctaagc aggagaatga ttcagagaac aacaggcttc ttcaggccgt accaggattg
721 gaacaggaaa cccctcccca ctatggatga ttccaaatta aagaaggtag ccaacatatt
781 cttgtgcact ttgtcttcac tattcaccag acccattaag gacataatag ggaagttgaa
841 acctcttaac atccttaaca ttctggctac atgtgattgg accttcgcag gcatagtgga
901 atccttaata ctcttggcag aactctttgg agttttctgg acacccccag atgtgtctgc
961 gatgatcgcc cccttgctag gtgattatga actgcaagga cctgaggacc ttgcagtgga
1021 actggtccca atagtgatgg gggggatagg tttggtgcta ggatttacca aagagaaaat
1081 cggaaagatg ctatcatccg ctgcatccac tttaagagct tgtaaagacc ttggtgcata
1141 cggactggaa atcttaaaat tggtcatgaa gtggttcttc ccaaagaaag aggaagcaaa
1201 tgaactggct atggtgagat ccatcgagga tgcagtgtta gacctcgagg caattgaaaa
1261 caaccacatg accaccctac tcaaagacaa agacagcttg gcaacctaca tgagaaccct
1321 tgaccttgag gaggagaaag ccagaaaact ctcaaccaaa tctgcttcac ccgatattgt
1381 gggcacaatc aactctcttc tggcaagaat cgctgctgca cgctccctag tgcatcgggc
1441 gaaagaagag ctctccagca ggccgagacc tgtcgttgtg atgatatcgg ggaggccagg
1501 gatagggaaa actcaccttg ccagggagct ggccaagaag atcgcggcct ccctcacagg
1561 ggaccagcgt gtgggcctta tcccacgcaa tggtgtcgac cattgggacg catacaaggg
1621 cgaaagagtt gtcctatggg acgactatgg aatgagcaac cccatccacg acgccctcag
1681 gttgcaggag cttgctgaca cttgccccct cacgctaaat tgtgacagaa ttgagaacaa
1741 agggaaagtc tttgacagtg atgccataat catcaccacc aatctggcca acccagcacc
1801 actggattat gtcaactttg aagcgtgctc gagacgtatt gatttcctcg tgtacgcaga
1861 agcccctgag gtggagaagg caaagcgcga cttcccaggt caacctgaca tgtggaagaa
1921 cgccttcagt cctgacttct cacacataaa actgtcattg gctccacagg gtggttttga
1981 caagaacggc aacaccccgc atggaaaagg ggtcatgaag accctcacca ctggctccct
2041 catcgcccga gcatcagggt tactccatga gaggctagat gaatatgaac tgcaaggccc
2101 agccctcacc accttcaact ttgaccgcaa caaggtactt gcttttagac aacttgctgc
2161 tgaaaacaag tatgggctga tggacacaat gagagttgga aaacagctca aggatgtcaa
2221 gaccatgtca gacctcaaac aagcactcaa gaacatcgcg atcaagaagt gccagatagt
2281 gtacaatggt ggcacctaca cacttgaggc tgatggcaag ggtagtgtga aagttgacaa
2341 agtgcaaagt gccactgtgc agaccaacaa tgaactagcc ggtgccctac accacctaag
2401 gtgcgctaga atcagatact atgtcaagtg cgtccaggag gcactgtatt ccatcatcca
2461 aatcgctggg gctgcattcg tcaccacgcg catcgctaag cgcatgaata tacaaaatct
2521 ctggtccaag ccacaggtgg aagacacaga agagatggcc aacaaagatg gttgcctaaa
2581 acccaaagat gatgaggagt ttgtcgtctc atccgacgac atcaaaactg agggcaagaa
2641 agggaagaac aagtctggcc gtggcaagaa gcacacagcc ttttcaagta aagggctcag
2701 tgatgaggag tacgatgagt acaagagaat cagagaagaa aggaatggta agtactccat
2761 agaagagtac cttcaggaca gagacaggta ctacgaggag gtggccattg ccagggcaac
2821 cgaagaggac ttctgtgaag aagaagaggc caaaatccgg cagagaattt tcagaccaac
2881 aaggaaacaa cgcaaagaag agagggcctc tctcggcttg gtcacaggct ctgaaatcag
2941 gaaaagaaac ccagaagact tcaaacccaa gggaaagctg tgggctgatg atgacagaag
3001 tgttgactac aatgagaaac tcaactttga ggccccacca agcatctggt cgcggatagt
3061 caactttggt tcgggctggg gcttctgggt ctcccccaat ctgtttataa catcaaccca
3121 tgtcataccc caaggtgcaa aagagttctt cggagtccct atcaagcaaa tccaaataca
3181 caagtcaggt gaattctgcc ggttgagatt cccaaagcca atcagaactg atgtgactgg
3241 catgattcta gaagaaggtg cgcccgaggg gaccgtggcc acactgctca tcaagagacc
3301 aactggagag ctcatgcctc tggcagccag aatggggacc catgcaacca tgaaaattca
3361 ggggcgcaca gttggagggc aaatgggtat gctcctgaca ggatccaacg ccaagagtat
3421 ggacctaggc acaacaccag gcgactgcgg ctgcccctac atctacaaga gggggaatga
3481 ctacgtggtc ataggagtcc atacggccgc tgcccgtgga ggaaacactg tcatatgtgc
3541 cacccagggg agtgagggag aagccacact tgaaggaggt gacagtaaag ggacatactg
3601 tggcgcacca atcttgggcc cagggagcgc tccgaagctc agcaccaaga ctaagttttg
3661 gagatcatcc acaacaccac tcccacctgg cacctacgaa ccagcctacc tcggtggcaa
3721 ggaccctaga gtcaaaggtg gcccttcatt gcaacaagtt atgagggacc agctgaagcc
3781 attcacagag cccagaggca aaccaccaag accaagtgtg ctggaggctg ccaagaaaac
3841 catcatcaat gtccttgagc aaacaattga tccaccccaa aaatggtcat ttgcgcaagc
3901 ttgcgcatcc cttgacaaaa ccacctccag cggccacccg caccacatgc ggaaaaacga
3961 ctgttggaat ggggagtcct tcacaggaaa attggctgat caagcctcca aggccaacct
4021 aatgtttgag gagggaaaga acatgactcc agtctacaca ggtgcactta aagatgagct
4081 ggtaaagacc gataaagttt atggtaaggt caagaagagg cttctgtggg gttcagatct
4141 agcgaccatg atacggtgcg cccgagcttt tggaggcctt atggatgaac tcaaggcaca
4201 ctgtgtcaca cttcctgtca gagttggtat gaacatgaat gaggatggcc ccatcatctt
4261 tgagaagcac tccagatata gatatcacta tgatgctgat tactcccggt gggactcaac
4321 acagcaaagg gatgtgctag caacagcact agaaatcatg gttaagttct ctccagaacc
4381 acacctggcc caaatagttg cagaagacct cctttcccct agcgtgatgg atgtaggtga
4441 ctttcaaata tcaataagtg agggtctccc ctctggggta ccttgtacct cccagtggaa
4501 ttccatcgcc cactggctcc tcactctgtg tgcactctct gaagtcacgg acctatcccc
4561 tgatattatt caggccaact cccttttctc cttctatggt gatgatgaga ttgtaagcac
4621 agatataaag ttggacccag agaagctgac agcaaaactc aaggagtacg ggctgaaacc
4681 aacccgccct gacaaaactg aaggacccct tgttatctct gaagacctgg atggcttgac
4741 attcctccgg agaactgtga cccgtgatcc agctggctgg tttggaaaat tagaacaaag
4801 ttcaattctc aggcaaatgt actggaccag gggtcctaac catgaagacc catttgaaac
4861 aatgatacca cactcccaaa gacccataca attgatgtcc ttgctgggcg aggctgcact
4921 ccacggcccg gcattctata gcaaaattag caaattagtc attgcagagt tgaaggaggg
4981 tggcatggat ttttacgtac ccagacaaga gccaatgttc agatggatga gattctcaga
5041 tctgagcacg tgggagggcg atcgcaatct ggctcccagt tttgtgaatg aagatggcgt
5101 cgagtgacgc caacccatct gatgggtccg cagccaacct cgtcccagag gtcaacaatg
5161 aggttatggc tctggagccc gttgttggtg ccgccattgc ggcacctgta gcgggccaac
5221 aaaatgtaat tgacccctgg attagaaata attttgtaca agcccctggt ggagagttca
5281 cagtatcccc tagaaacgct ccaggtgaaa tactatggag cgcgcccctg ggccctgatc
5341 taaatcccta cctatcccat ttggccagaa tgtacaatgg ttatgcaggt ggttttgaag
5401 tgcaggtaat tctcgcgggg aacgcgttca ccgccgggaa ggtcatattt gcagcagttc
5461 caccaaattt tccaactgaa ggcttgagcc ccagccaggt cactatgttt ccccatatag
5521 tagtggatgt taggcaatta gaacctgtgt tgattccctt acccgatgtt aggaataatt
5581 tctatcatta caatcaatca aatgacccca ccattaagtt gatagcaatg ttgtatacac
5641 cacttagggc taataatgct ggggatgatg tcttcacagt ttcctgccga gttctcacga
5701 gaccatcccc cgattttgat ttcatattcc tagtgccacc cacagttgag tcaagaacta
5761 aaccattctc tgtcccagtt ttaactgttg aggagatgac caattcaaga ttccccattc
5821 ctttggaaaa gttgttcacg ggtcccagca gtgcctttgt tgtccaacca caaaacggca
5881 ggtgcacgac tgatggcgtg ctcctaggca ccacccaact gtctcctgtc aacatctgca
5941 ccttcagagg agatgtcacc cataccacag gtagtcataa ctacacaatg aatttggctt
6001 ctcaaaattg gagcaattat gacccaacag aagaaatccc agcccctcta ggaactccag
6061 attttgtggg gaagattcag ggcgtgctca cccaaaccac aaggacagat ggctcaacac
6121 gcggccacaa agccacagtg tatactggga gcgccgactt tgctccaaaa ctgggtagag
6181 ttcaatttga aactgacaca aaccatgatt ttgaagctaa ccaaaacaca aagttcaccc
6241 cagttggtgt catccaagat ggtggcacca cccaccgaaa tgagccccaa cagtgggtgc
6301 tcccaagtta ctcaggcagg aacactccca atgtgcatct ggcccccgct gtagccccca
6361 cttttccggg tgagcaactt ctcttcttca gatccaccat gcccggatgc agcgggtacc
6421 ccaacatgga tttggactgt ctgctccccc aggaatgggt gcagtacttc taccaagagg
6481 cggccccagc acaatctgat gtggctctgc taagatttgt gaatccagac acaggtaggg
6541 ttttgtttga gtgtaagctt cataaatcag gctatgttac agtggctcac actggccaac
6601 atgatttggt tattcccccc aatggttatt ttaggtttga ttcctgggtc aaccagttct
6661 acacgcttgc ccccatggga aatggaacgg ggcgtagacg tgcactataa tggctggagc
6721 tttctttgct ggattggcat ctgatgtcct tggctctgga cttggttccc ttatcaatgc
6781 tggggctggg gccattaacc aaaaagttga gtttgaaaat aacagaaaat tgcaacaagc
6841 atccttccaa tttagcagca atctacaaca ggcttccttt caacatgaca aagagatgct
6901 ccaagcacaa attgaggcca ccaaaaggct acaacaggaa atgatgaaag ttaagcaggc
6961 aatgctcctg gagggtggat tctctgagac agatgcagct cgcggggcaa tcaacgcccc
7021 catgacaaaa gctttggact ggagcgggac aaggtactgg gctcccgacg ctaggactac
7081 aacatacaat gcaggccgct tttccacccc tcaaccatcg ggggcactgc caagaagagc
7141 taatctcagg gatactgtcc ctactcgggg ttcctccagt aagtcttcta attcttctac
7201 tgctacttct gtgtactcaa atcaaaccac ttcaacgaga cttggttcta cagctggttc
7261 tggcaccagt gtctcgagct tcccgtcaac tgcaaggact aggagctggg ttgaggatca
7321 aaacaggaat ttgtcacctt tcatgagggg ggcccacaac atatcgtttg tcaccccacc
7381 atctagcaga tcctctagcc aaggcacagt ctcaaccgtg cctaaagaga ttttggactc
7441 ctggactggc gctttcaaca cgcgcaggca gccactcttc gctcacattc gtaagcgagg
7501 ggagtcacgg gcgt
//