Typing tool
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Typing tool
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Complete norovirus genomes
| OP609644 | GII.10 | |
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| GII.P16 |
ORF1: 5..5104
ORF2: 5085..6731
ORF3: 6731..7504
LOCUS OP609644 7543 bp RNA linear VRL 16-OCT-2022
DEFINITION Norovirus GII isolate Hu/US/2021/GII.10[P16]/Genesee0003
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION OP609644
VERSION OP609644.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7543)
AUTHORS Montmayeur,A.M.M., Mosher,L., Xu,R., Barclay,L., Vinje,J. and
Chhabra,P.
TITLE Direct Submission
JOURNAL Submitted (07-OCT-2022) Viral Gastroenteritis Branch, Centers for
Disease Control and Prevention, 1600 Clifton Road NE, Atlanta, GA
30329, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. v. 11.1.2; SPAdes v. v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7543
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="Genesee0003"
/isolate="Hu/US/2021/GII.10[P16]/Genesee0003"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="09-Apr-2021"
/note="Amplicon sequencing: First 35 nt may represent
primer sequence;
genotype: GII.10[P16]"
gene 5..5104
/gene="ORF1"
CDS 5..5104
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="UYA57428.1"
/translation="MKMASNDASAAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARP
KQPAPRDKPQKPPRPPTPELVKRIPPPPPNGEEEEEPVIRYEVKSGISGLPELTTVPQ
PDVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAA
ISMARVELTPLSLYWRVVYTPQYLISPEALRRLNGEAFPYTAFDNNCYAFCCWVLDLN
DSWLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLI
GKIKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGP
EDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWF
FPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRL
STKSASPDIVGTINALLARIAAARSLVHRAKEELSSRMRPVVVMISGKPGIGKTHLAR
EVATKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELAD
TCPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEV
EKAKRDFPGQPDMWKDAFKSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIA
RASGLLHERMDEFELQGPTITTFNFDRNRITAFRQLAAENKYGLVDTMKVGNQLKGVK
TMEELKQAIRNVTIKRCQIIYGGSTYDLESDGKGKVLVERVKNTSVQTNNELAGALHH
LKHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESETKEE
APKSEDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLV
TGSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSP
SLFITSTHVIPAGMTEAFGVSIKQIQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEG
TVASVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILG
PGGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLRPFTEP
RGKPPRPNVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFW
NGETFTGKLADQASKANLMFEEGKHMTPVFTAALKDELVKTEKIYGKIKKRLLWGSDL
STMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWD
STQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTAKLK
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGP
NHEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide 5..1000
/gene="ORF1"
/product="p48"
mat_peptide 1001..2098
/gene="ORF1"
/product="NTPase"
mat_peptide 2099..2629
/gene="ORF1"
/product="p22"
mat_peptide 2630..3028
/gene="ORF1"
/product="VPg"
mat_peptide 3029..3571
/gene="ORF1"
/product="Pro"
mat_peptide 3572..5101
/gene="ORF1"
/product="RdRp"
gene 5085..6731
/gene="ORF2"
CDS 5085..6731
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="UYA57429.1"
/translation="MKMASNDAAPSSDGAAGLVPESNTEVMALEPVAGASLAAPVTGQ
TNIIDPWIRMNFVQAPNGEFTVSPRNSPGEVLLNLELGPELNPYLAHLSRMYNGYAGG
MEVQIMLAGNAFTAGKLIFAAVPPHFPVENLSPPQITMFPHVIIDVRTLEPVLLPMPD
IRNSFFHFIQRDEPKMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFDFTYLVPP
TVESKSKPFTLPILTLGELTNSRFPLPIDMLYTNPNESAVVQCQNGRCTLDGELQGTT
QLLPTGICAFRGKVTQQVQDDHRGTHWNMTVTNLNGTPFDPTEDIPAPLGTPDFSGQI
YGVISQRNTNTVPAEGNLPANRAHEAVIATYSPKFTPKLGNIQFSTWETQDVSTGQPT
KFTPVGLASVDANSHFDQWTLPSYSGALTLNMNLAPSVAPVFPGECLLFFRSFIPLKG
GYGNPAIDCLLPQEWVQHLYQESAPSLSDVALVRYVNPETGRTLFEAKLHRNGFLTVA
RNSTGPVVAPTNGYFRFDSWVNQFYTLAPMGNGSGRRRMQ"
gene 6731..7504
/gene="ORF3"
CDS 6731..7504
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="UYA57430.1"
/translation="MAGAFVAGLAGDVLSNGIGSLINAGANAINQRAEFDFNRQLQQN
SFNHDKEMLQAQVQATKQLQADMIAIKQGVLAAGGFSPTDAARGAVNAPMTQALDWSG
TRYWAPGAMKTSSYSGRFISTTPSRQVEFPQRKNAAPSTGSSYGGSSRSTVSTTLSSS
VSSSSRASPLTQSSLVSNSSSSRSRTSDWVREQNRSLEPFMHGALQTTFVTPPSSKAS
SNGTVSTVPKGVLDSWTPAFNTRRQPLFAYLRPKGESQV"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgcttc cgctgccgtt gcttgcaaca acaacaacga
61 caaagaaaaa tcttcaggtg aaggcttatt cacaaatatg tcttccacct taaagaaagc
121 cctcggggct aggcccaaac agcctgcccc gagagacaaa ccacaaaagc ccccaagacc
181 accaactccc gagttggtca agaggatacc ccctcctcca cctaatggcg aagaagaaga
241 agaaccagtc attagatatg aggttaagag tgggatttct ggcctgcccg agctcacaac
301 agtcccccaa ccggacgtgg ccaacacagc attcagtgtc ccaccactga gcttgagaga
361 aaacagggag gccaaggaac cgctaacagg ggcaatatta gagatgtggg atggagagat
421 ataccactat ggcctgtacg tggagaaagg cttagtgtta ggtgtgcaca aaccacctgc
481 agccataagt atggcaagag tggagttgac gccgctgtca ttgtactggc gtgtggtgta
541 cactccccaa tacctcatct cccctgaagc tctcaggagg ctcaatggag aggcattccc
601 ttataccgcc tttgacaaca actgctatgc cttttgctgt tgggtattag acctcaatga
661 ctcatggctt agcaggagga tggtacaaag aacaacgggc ttcttcagac cttaccaaga
721 gtggaacaga aaacccctgc ccacaatgga tgactccaaa attaagaagg tagcaaatat
781 attcctatgt tcactgtcca cattattcac caggcccata aaagatctca taggaaaaat
841 taaaccatta aacatactga acatcctggc aacgtgtgac tggacttttg ccggaatagt
901 ggagtctctg atattacttg ctgaactctt cggagttttc tggacacccc cagatgtgtc
961 tgctatgatc gcccccttac tcggggacta cgagttgcaa gggccagaag acctcgccgt
1021 tgaactcgta cctgtggtaa tgggggggat tggtttggtg ttgggattca ctaaagagaa
1081 aattggcaaa atgttatcct cagcagcatc aacgctcagg gcttgcaaag accttggtgc
1141 ctatggctta gagatactca aattggtcat gaagtggttc ttcccaaaga aagaggaggc
1201 caatgagtta gccatggtga gggccataga ggatgctgta ctagatcttg aggcaataga
1261 aaataaccac atgacaacct tgttgaaaga caaagacagc ttagcaacat acatgaaaac
1321 actggacatg gaggaggaga aagccaggag gttgtccaca aaatctgcat cccctgacat
1381 agttgggaca atcaacgccc tgctggctcg aatagcagca gccaggtcat tagttcacag
1441 ggccaaggaa gagctatcta gcaggatgag accagtagtt gttatgatat ctggcaaacc
1501 aggaataggc aaaactcatc tggctaggga ggtggcaaca aaggtggcat ccactctcac
1561 aggggatcaa agagtcggac tcataccacg aaacggtgtg gaccattggg atgcatacaa
1621 aggtgagaga gtcgtgttgt gggacgacta tggcatgagt aacccaatcc atgatgctct
1681 tcgcatacaa gaattggctg atacgtgtcc cctcacctta aattgtgaca gaattgaaaa
1741 taagggaaaa gtttttgaca gtgaagtcat aataattaca acaaaccttg ccaatccagc
1801 cccacttgat tatgtcaact ttgaagcctg ttccaggaga attgatttcc tggtgtacgc
1861 tgaggcacca gaagtagaaa aggcaaaacg ggacttccct ggtcagccag atatgtggaa
1921 ggacgccttc aagtcggact tttcacacat caagctacag cttgcacccc agggcggctt
1981 tgacaaaaat ggcaacaccc cacatgggaa aggagtgatg aagaccctca ctaccggttc
2041 tctgattgcc cgtgcatcag gcctactgca tgagaggatg gatgaatttg aactccaagg
2101 tcccacgatc accaccttta atttcgaccg gaacagaatc acagcattca gacaattggc
2161 tgcagaaaac aagtatggat tggtggacac catgaaagtt ggcaatcaat taaaaggagt
2221 gaaaaccatg gaagaactca aacaagcaat caggaatgtg accatcaaga ggtgccagat
2281 catctacggt ggttccacgt atgaccttga atctgatggc aagggcaaag ttttggtgga
2341 aagggtcaag aacacctctg tacagaccaa caatgagttg gctggggccc tgcaccatct
2401 caaacatgcc cgaatcaggt actacgtcaa atgtgtacaa gaagcagtct attccatcat
2461 acaaattgcc ggcgctgcgt tcgtcaccac gcgcattgca cgccgcatga atatacaaga
2521 actctggtcg aagccacaat tagatcaaaa tgaatcagag actaaggaag aggcccccaa
2581 gtcagaagac gacgagttca tcatatcttc taaggacatt aaggaggaag gaaagaaggg
2641 taaaaacaaa actggtcgtg gcaagaaaca caccgcattc tccagcaagg gcttgagcga
2701 tgaggagtat gacgagtaca agagaataag agaagaaaga aatgggaagt actctataga
2761 ggagtatctt caagacagag acaggtacta tgaggaactc gccattgcca aggccacgga
2821 agaagacttc tgtgaagagg aggagatcaa aatccgtcag agaattttcc gtcccaccag
2881 gaaacaaaga aaggaagaaa gggccacatt agggctagtg acaggttcag aaatcagaaa
2941 gagaaaccct gatgacttca aacccaaagg gaagctgtgg gccgatgaca acaggagtgt
3001 tgactacaat gaaaaactgg actttgaggc ccctccaagc atatggtcta ggattgtgag
3061 ctttggttct ggctggggct tctgggtgtc accaagcctt ttcataacat caactcatgt
3121 aatccccgca ggcatgacag aagcatttgg agtctccatt aaacaaatac agatccacaa
3181 atcaggagag ttttgccgat tcagattccc aaaaccaatt agaccagatg tgacaggaat
3241 gattttggag gaaggtgcgc ctgagggcac cgtggcatct gtgctcatca aacgccctac
3301 cggagagctc atgcctcttg cagccagaat gggaacacac gcaaccatga aaattcaagg
3361 ccgcatggta ggcggacaga tgggtatgtt gctcactgga tcgaatgcta aaggaatgga
3421 tttgggaaca actcctggtg actgtggctg tccttacatc tataaaaggg gcaatgacta
3481 tatagtcatt ggggtgcaca ctgcagcagc ccgtggtgga aacaccgtca tttgtgccac
3541 acagggaagt gaaggtgagg caactcttga gggtggagat gacaaaggaa catactgtgg
3601 ggcgcccatt ctaggccctg ggggtgcacc aaaattgagc accaaaacca aattttggag
3661 gtcatcaaac acgccccttc caccagggac atatgagcct gcctacctcg gtggccgtga
3721 tccgcgtgtt aagggtgggc cctccctgca acaggtgatg agagaccagt tgaggccatt
3781 tactgagccc aggggcaagc ctccaagacc aaatgtattg gaagcagcca aacaaaccat
3841 catcaatgtc ctcgaacaaa ccctggaccc cccacaaaaa tggacatacg cacaggcgtg
3901 tgcctcactt gacaaaacca cctccagcgg gcatccccat cacgtccgaa agaatgaatt
3961 ctggaatggt gagaccttca ctggtaaact ggcagaccaa gcatcaaaag caaacctaat
4021 gttcgaggaa gggaaacaca tgacaccagt gttcacagca gcactcaagg acgagctagt
4081 caagactgag aaaatctatg gaaagatcaa gaagagactg ctctggggct ctgacttgtc
4141 caccatgatc cggtgcgcta ggtcgtttgg tggactcatg gacgagatga aggcacactg
4201 catatcactc ccagtccgag ttggcatgaa tatgaatgaa gacggcccaa taatatttga
4261 gaaacattcc aggtacaaat atcactatga tgcagactac tctcgttggg attcaacaca
4321 acagagggca gtactagcag cagccttgga aatcatggtc agattttctg cagaaccaca
4381 attggcacaa atagtcgctg aggatctgct ggcccctagt gttgtagatg taggtgactt
4441 taaaattaca ataaatgaag ggctcccttc tggtgtgcca tgcacttctc aatggaactc
4501 catcgcacac tggctgctaa ctctttgtgc cttgtctgaa gtcaccaaac tgtcccctga
4561 catcatacag gcaaactcca tgttctcatt ctacggtgat gacgagattg tcagcactga
4621 tataaaattg gaccctgaac agttaaccgc caaattgaag gagtacggcc tgaaaccaac
4681 ccgcccagac aaaaccgagg gacccctgat tatcagtgaa gatttgaacg gtctcacttt
4741 cctccggagg acggtgactc gtgacccagc tggctggttt ggaaagctgg accaaagctc
4801 aattttgagg cagatgtact ggaccagagg accaaatcat gaagatccca atgagacaat
4861 gataccccat tctcaaagac ctatacagct catggcactg cttggtgaag cctctcttca
4921 cggaccctct ttctacagca aaatcagcaa attggtcata actgaactca aagaaggtgg
4981 gatggacttt tacgtgccaa ggcaggaacc catgttcagg tggatgaggt tttctgactt
5041 gagcacgtgg gagggcgatc gcaatctggc tcccaatttt gtgaatgaag atggcgtcga
5101 atgacgccgc tccatctagt gatggtgcag ccggcctcgt gccagaaagt aatactgagg
5161 ttatggctct tgaacctgta gctggggcgt ctttagctgc ccctgtgacg ggtcaaacaa
5221 atataattga cccatggata agaatgaact ttgttcaagc cccaaatgga gagtttactg
5281 tttccccaag aaattcccct ggagaagtac tcctaaattt ggaactgggt cctgaattaa
5341 atccttatct ggcacattta tccaggatgt acaatggcta tgctggaggc atggaagttc
5401 agattatgct agctgggaac gcgttcactg ctggcaaact gatctttgct gctgtgcctc
5461 cacattttcc cgttgaaaat ctgagccctc cccaaattac aatgttccca catgtgatta
5521 tagatgttag aaccttagaa cctgtgttac tccctatgcc tgacatcagg aactccttct
5581 ttcacttcat ccagagggat gagccaaaaa tgaggttggt ggcaatgcta tacacaccac
5641 taaggtccaa tggttctgga gatgatgtat tcacagtttc atgtagggtt ctgacccgtc
5701 ctacccctga ttttgatttt acttacttgg taccaccaac tgttgaatca aagagcaaac
5761 cctttacttt gcctatatta acattgggag aattgacaaa ttctaggttt cccttgccca
5821 ttgatatgtt gtacaccaac ccaaatgaaa gtgcagttgt tcagtgccaa aatggtaggt
5881 gcaccctgga cggtgagctg cagggaacaa cccaactttt gcccacaggc atctgcgcat
5941 ttaggggcaa ggtcactcaa caggtgcagg atgatcacag gggcacacac tggaacatga
6001 cagtgaccaa cttgaatggg actccgtttg atccaactga ggacatccct gccccactag
6061 gcacaccgga cttctccggt caaatttatg gggtaataag tcagagaaac accaacacag
6121 ttcccgcaga aggaaatctt ccggccaacc gggctcatga agctgtgatt gcaacctaca
6181 gtcccaaatt cacacccaaa ttgggcaaca tccaatttag tacttgggaa acccaagatg
6241 tgagcactgg acaacctacc aagttcaccc cagttggctt ggcctctgtg gatgctaact
6301 cccattttga tcaatggact ctccccagct actctggtgc tttaacttta aatatgaatt
6361 tggccccatc tgtcgcccca gtctttcctg gggagtgtct tctattcttt aggtctttta
6421 tcccactgaa ggggggctat gggaaccccg ccattgattg cctgttgcca caagagtggg
6481 tccagcatct ctatcaggag tcagcaccat ctcttagcga tgtggctttg gtgaggtatg
6541 tgaacccaga gactggacgc accctcttcg aagccaagtt gcacaggaat ggattcctga
6601 ctgttgctag gaacagtact ggacctgtcg tggcccccac aaatggatat tttagatttg
6661 attcctgggt caaccagttt tatactttag cccccatggg aaatggcagt gggcgtagaa
6721 gaatgcagta atggctggag cttttgtagc aggtttggcc ggtgacgttc ttagcaacgg
6781 aatcgggtca ctcatcaatg ctggtgccaa tgcaattaat caaagagctg aatttgattt
6841 taacaggcag ttacaacaaa attcttttaa tcatgacaaa gagatgctcc aggcccaagt
6901 tcaagcaaca aagcagctgc aagcagacat gatcgccatc aagcaggggg tgttggccgc
6961 tggcggcttc tcccccactg atgcagcaag aggggcagtt aacgctccta tgacacaggc
7021 tttggactgg agtggcacga gatattgggc tccaggtgcc atgaaaacat ccagctattc
7081 aggcaggttt atatcgacca ctccatctag gcaagttgag tttcctcagc gtaagaatgc
7141 tgccccctcc actggctctt cttatggtgg gtcttctaga tctacagtct ctactactct
7201 cagttcttct gtatcttcta gttctagagc ttcaccccta acccaatcta gtttggtttc
7261 taattcttct tcatcaagat caagaactag tgactgggtg cgtgagcaaa accggagcct
7321 agaacccttt atgcatgggg ctttgcagac tacctttgtc actcctccat caagcaaagc
7381 ttctagcaat gggacggtct cgaccgttcc aaaaggtgtt ttggactctt ggacacctgc
7441 gtttaacacc cgcaggcagc cgcttttcgc ataccttcga ccgaagggag agtcacaagt
7501 ttagtgaaaa gattgatttt cttttaaatt tctcttttaa aaa
//