Typing tool
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Typing tool
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Complete norovirus genomes
| OP205541 | GII.2 | |
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| GII.P16 |
ORF1: 1..5100
ORF2: 5081..6709
ORF3: 6709..7488
LOCUS OP205541 7488 bp RNA linear VRL 21-JUN-2023
DEFINITION Norovirus GII isolate RIVM-NOV-2017-0180_R02-19 nonstructural
polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes, complete cds.
ACCESSION OP205541
VERSION OP205541.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7488)
AUTHORS Schmitz,D., Zwagemaker,F., van der Veer,B., Vennema,H., Bosch,T.,
Laros,J.F., Koopmans,M.P., de Graaf,M. and Kroneman,A.
TITLE Shotgun whole genome sequencing for gastroenteritis surveillance
using Norovirus as a model
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7488)
AUTHORS Schmitz,D., Zwagemaker,F., van der Veer,B., Vennema,H., Bosch,T.,
Laros,J.F., Koopmans,M.P., de Graaf,M. and Kroneman,A.
TITLE Direct Submission
JOURNAL Submitted (05-AUG-2022) Center for Infectious Diseases,
Rijksinstituut voor Volksgezondheid en Milieu, Antonie van
Leeuwenhoeklaan 9, Bilthoven, Utrecht 3721 MA, Netherlands
COMMENT ##Assembly-Data-START##
Assembly Method :: SPAdes v. v3.11.0
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7488
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="RIVM-NOV-2017-0180_R02-19"
/isolation_source="Human feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Netherlands"
/collection_date="2017-02-16"
/note="genotype: GII.2[P16]"
gene 1..5100
/gene="ORF1"
CDS 1..5100
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="UUV60924.1"
/translation="MKMASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARP
KQPAPRDKPQKPPRPPTPELVKRIPPPPPNGEEEEEPVIRYEVKSGVSGLPELTTVPQ
PDVANTAFSIPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAA
VSMARVELTPLSLYWRVVYTPQYLISPETLRKLNGEAFPYTAFDNNCYAFCCWVLDLN
DSWLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANILLCSLSTLFTRPIKDLI
GKIKPLNILNILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGP
EDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWF
FPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDMEEEKARRL
STKSASPDIVGTINALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLAR
EVARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELAD
TCPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPEV
EKAKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIA
RASGLLHERMDEFELQGPTITTFNFDRNRITAFRQLAAENKYGLVDTMRVGNQLKGVK
TMEELKQAIRNVTIKRCRIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHH
LKHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESETKEE
APKSGDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLV
TGSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSP
SLFITSTHVIPAGITEAFGVPIKQIQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEG
TVATVLIKRPTGELMPLAARMGTHAAMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILG
PGGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDSRVKGGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPYHVRKNEFW
NGETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKIYGRIKKRLLWGSDL
STMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWD
STQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTAKLK
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGP
NHEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide 1..996
/gene="ORF1"
/product="p48"
mat_peptide 997..2094
/gene="ORF1"
/product="NTPase"
mat_peptide 2095..2625
/gene="ORF1"
/product="p22"
mat_peptide 2626..3024
/gene="ORF1"
/product="VPg"
mat_peptide 3025..3567
/gene="ORF1"
/product="Pro"
mat_peptide 3568..5097
/gene="ORF1"
/product="RdRp"
gene 5081..6709
/gene="ORF2"
CDS 5081..6709
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="UUV60925.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYIPLKGGYGNPA
IDCLLPQEWVQHFYQESAPSMSEVALVRYINPDTGRSLFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6709..7488
/gene="ORF3"
CDS 6709..7488
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="UUV60926.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPNSMRTTYYSGKFTSTVPVRQADFQHTQSRPSSGSSVSSFATQSSRPTLTTTT
GSSHGTVSSNSTRSTSLSQSTVSRATSRTGEWVRDQNRNLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 atgaagatgg cgtctaacga cgctaccgtt gccgttgctt gcaacaacaa caacgacaaa
61 gaaaaatctt caggtgaagg tttattcaca aatatgtctt ccaccttaaa gaaagccctc
121 ggggctaggc ccaaacagcc tgccccgaga gacaaaccac aaaagccccc aagaccacca
181 actcccgagt tggtcaagag gataccccct cctccaccta atggcgaaga agaagaagaa
241 ccagttatta ggtatgaggt taagagtggg gtctctggcc tgcccgagct cacaacagtc
301 ccccaaccgg acgtggccaa cacagcattc agtattccac cactgagctt gagagaaaac
361 agggaggcca aggaaccgct aacaggggca atattagaga tgtgggatgg agagatatac
421 cactatggcc tgtacgtgga gaaaggctta gtgttaggtg tgcacaaacc acctgcagcc
481 gtaagcatgg caagagtgga gctgacgccg ctgtcattgt actggcgagt ggtgtacact
541 ccccaatacc tcatctcccc tgaaactctc aggaaactca acggagaggc attcccttac
601 accgcctttg acaataactg ctatgccttt tgctgctggg tgttagacct caatgactca
661 tggcttagca ggaggatggt gcaaagaaca acgggcttct tcagacctta ccaagagtgg
721 aacagaaaac ccctgcccac catggatgac tccaaaatta agaaggtggc aaatatatta
781 ctatgttcat tgtccacatt attcaccaga cccataaaag acctcatagg aaaaattaaa
841 ccattaaaca tattgaatat cctggcaacg tgtgactgga cttttgccgg aatagtggag
901 tctctgatat tacttgctga actcttcgga gttttctgga cacccccaga tgtgtctgct
961 atgatcgctc ccttactcgg ggactacgag ttgcaggggc cagaagacct cgccgttgaa
1021 ctcgtacctg tggtaatggg ggggattggt ttggtgttgg gattcaccaa agagaaaatt
1081 ggcaaaatgt tgtcctcagc agcatcaaca ctcagggctt gcaaagatct tggtgcctat
1141 ggcttagaga tactcaaatt ggtcatgaag tggttcttcc caaagaaaga ggaggccaat
1201 gagttagcca tggtgagggc catagaggat gctgtactag atcttgaggc aatagagaat
1261 aaccacatga caaccctgtt gaaagacaaa gacagcttag caacatacat gagaacactg
1321 gacatggagg aggagaaagc caggaggttg tccacaaaat ctgcatcccc tgacatagtt
1381 gggacaatca acgccctgct ggctcgaata gcagcggcca ggtcattagt ccacagggcc
1441 aaggaagagc tatctagcag gataagacca gtagttgtta tgatatctgg caaaccagga
1501 ataggcaaaa ctcatctggc cagggaggtg gcaagaaagg tggcgtccac tctcacaggg
1561 gatcaaagag tcggactcat accaagaaac ggtgtggacc attgggatgc atacaaaggt
1621 gagagagtcg tgctgtggga cgactatggc atgagtaacc ccattcatga tgctcttcgc
1681 atacaagaat tggctgatac gtgtcccctt accttaaatt gtgacagaat tgaaaataag
1741 ggaaaagttt ttgacagtga ggtcataata attacaacaa accttgccaa tccagcccca
1801 cttgattatg ttaactttga ggcctgttcc aggagaattg atttcctggt gtacgctgat
1861 gcaccagaag tagaaaaggc aaaacgggac tttcctggtc agccagatat gtggaaggac
1921 gccttcaagc cggacttttc acacatcaag ctacagcttg caccccaggg cggctttgat
1981 aagaatggca acaccccaca tgggaaagga gtgatgaaga ccctcactac cggttctctg
2041 attgcccgtg catcaggcct actgcatgag aggatggatg aatttgaact ccaaggtccc
2101 acaatcacca ccttcaattt cgaccggaac agaatcacag cattcagaca attggctgca
2161 gaaaacaagt atggattggt ggataccatg agagttggca atcaactaaa aggagtgaaa
2221 accatggagg aacttaaaca agcaatcagg aatgtgacca tcaagaggtg ccggatcatc
2281 tacggtggct ccacgtatga ccttgaatct gatggcaagg gcaaagtttt ggtggaaaag
2341 gtcaagaaca cctctgtaca aaccaacaac gagttggctg gggccctgca ccatctcaaa
2401 cacgcccgaa tcaggtacta cgtcaaatgt gtgcaagaag cagtctattc catcatacaa
2461 attgccggcg ctgcgtttgt caccacgcgc attgcacgcc gcatgaacat acaagaactc
2521 tggtcgaagc cacaattaga tcaaaatgaa tcagagacta aggaagaggc ccccaagtca
2581 ggagatgacg agttcatcat atcttctaag gacatcaagg aggaaggaaa gaagggcaaa
2641 aacaaaactg gccgtggcaa gaaacacact gcattctcca gcaagggctt gagcgatgag
2701 gagtatgacg agtacaagag gataagagaa gagagaaatg ggaagtactc catagaggag
2761 tatcttcaag acagagacag gtactatgag gagctcgcca ttgccaaggc cacggaagaa
2821 gacttctgtg aagaggagga gatcaaaatc cgtcagagaa ttttccgtcc caccaggaaa
2881 caaagaaagg aagagagggc cacattaggg ctagtaacag gttcagaaat cagaaaaaga
2941 aaccctgatg acttcaaacc caaagggaag ctgtgggccg atgacaacag gagtgttgac
3001 tacaatgaga aactggactt tgaggccccc ccaagcatat ggtccaggat tgtgagcttt
3061 ggttctggct ggggcttctg ggtgtcacca agtcttttca taacgtcaac tcatgtaatc
3121 cccgcaggca taacagaagc atttggagtc cccatcaaac aaattcagat ccacaaatca
3181 ggtgaatttt gccgattcag attcccaaaa ccaatcagac cagatgtgac agggatgatc
3241 ttggaagaag gtgcgcctga gggcaccgtg gcaactgtgc tcatcaaacg ccccaccgga
3301 gagctcatgc ctcttgcagc cagaatggga acacacgcag ccatgaaaat tcaaggccgc
3361 atggttggcg gacagatggg tatgttgctc actggatcaa atgctaaagg aatggatttg
3421 ggaacaactc ctggtgactg tggctgtcct tacatctata aaaggggcaa tgactatata
3481 gtcattgggg tgcacactgc agcagcccgt ggtggaaaca ccgtcatctg tgccacacag
3541 ggaagtgagg gtgaggcaac tcttgagggt ggagatgaca aaggaacata ctgtggggca
3601 cccattctag gccctggggg tgcaccaaaa ttgagcacca aaaccaaatt ttggaggtca
3661 tcgaacacgc cccttccacc agggacatat gaacctgcct acctcggtgg ccgtgattcg
3721 cgtgttaagg gtgggccctc cctgcagcag gtaatgagag accagttgaa gccattcact
3781 gaacccaggg gcaaacctcc aagaccaagt gtattggaag cagccaaaca aaccatcatc
3841 aatgtcctcg aacaaaccct ggaccctcca caaaaatgga catacgcaca ggcgtgtgcc
3901 tcacttgaca aaaccacctc cagcgggcat ccctatcacg tccgaaagaa tgaattctgg
3961 aatggtgaga ccttcactgg taaattggca gaccaagcat caaaagcaaa cctaatgttt
4021 gaggaaggga aacacatgac accagtgtac acagcagcac tcaaggacga gctagtcaag
4081 actgagaaaa tctatggaag gatcaagaag agactgctct ggggctctga cttgtccacc
4141 atgatccggt gcgctaggtc atttggtggg ctcatggacg agatgaaggc acactgcata
4201 tcactcccag tccgagttgg catgaatatg aatgaagatg gcccaataat atttgagaaa
4261 cattccaggt acaaatatca ctatgatgca gactactctc gttgggattc aacacaacag
4321 agggcagtac tagcagcagc cttggaaatt atggtcagat tctctgcaga accacaattg
4381 gcacaaatag tcgctgagga tctgctggcc cctagtgtag tagatgtagg agactttaaa
4441 attacaataa atgaagggct cccctctggt gtgccatgca cttctcaatg gaactccatc
4501 gcacactggc tgctaacact ctgtgccttg tctgaagtca ccaaactgtc ccctgacatt
4561 atacaggcaa attccatgtt ctcattttac ggtgatgacg agattgtcag caccgacata
4621 aaattggacc ctgaacagtt aaccgccaaa ttgaaggagt acggcctgaa accaacccgc
4681 ccagacaaaa ccgagggacc cctgattatc agtgaagatt tgaacggact cactttcctc
4741 cgaaggacag tgactcgtga cccagctggc tggtttggaa aactggacca aagctcaatt
4801 ttgaggcaga tgtactggac tagaggacca aatcatgaag accccaatga gacaatgata
4861 ccccattctc aaagacccat acagctcatg gcactgcttg gtgaagcctc tcttcacgga
4921 ccctctttct acagtaaaat cagtaaattg gtcataactg aactcaaaga aggtgggatg
4981 gacttttacg tgccaaggca ggaacccatg ttcaggtgga tgaggttttc tgacttgagc
5041 acgtgggagg gcgatcgcaa tctggctccc aattttgtga atgaagatgg cgtcgaatga
5101 cgccgctcca tctactgatg gtgcagccgg cctcgtgcca gaaagtaaca atgaggtcat
5161 ggctcttgaa cccgtggctg gtgccgcctt ggcagccccg gtcactggtc aaacaaatat
5221 tatagaccct tggattagag caaattttgt ccaggccccc aatggtgaat ttacagtctc
5281 tccccgtaat gcccctggtg aagtgctact gaatctagag ttgggtccag aattaaatcc
5341 ttatctggca catttagcaa gaatgtacaa tgggtatgcc ggtgggatgg aggtgcaggt
5401 catgttggct gggaacgcgt tcacagccgg caagttggtc ttcgccgccg tgccacctca
5461 cttcccagtt gaaaacctta gcccacagca aatcaccatg ttccctcatg tgatcataga
5521 tgtgagaacc ttggaacctg ttctgttacc actccctgat gttaggaata atttcttcca
5581 ttataatcag aaagatgatc ccaagatgag aattgtggct atgctttaca cccccctcag
5641 gtctaatggt tcaggtgatg atgtgtttac agtctcctgc agagtgttga ctagaccttc
5701 ccctgacttt gacttcacat acctggtgcc accaacagtg gagtctaaaa caaaaccatt
5761 caccctccca atcctcacac ttggggaact ttctaattcc aggttcccag tgtccataga
5821 ccagatgtat accagcccta atgaagtcat atcagtgcag tgtcaaaatg gtaggtgcac
5881 actggacggg gagctccagg ggacaacaca actccaagtc agtggcattt gtgctttcaa
5941 aggtgaagtg accgcccact tgcatgacaa tgatcaccta tataatgtta ccatcacaaa
6001 cttgaatggg tccccttttg atccctccga ggatatccct gcccctctgg gtgtgcctga
6061 cttccaggga agggtttttg gtatcatctc ccaaagggac aaacacaata gtcctgggca
6121 taatgaacca gcaaacaggg gacacgacgc tgtggttccc acttacacag cacagtacac
6181 tccaaaactg ggacaaattc aaattggcac atggcagact gacgacctta cagtcaacca
6241 accagtcaaa ttcaccccag ttggactcaa tgacactgaa cattttaacc aatgggtggt
6301 ccccaggtat gctggtgccc taaacctcaa tacaaacctt gccccttctg ttgctccagt
6361 atttccagga gagcgtctgc tcttcttcag atcatacatt cccctcaagg gcggttatgg
6421 aaacccagcc attgattgcc tactaccaca agagtgggtg caacacttct atcaggaatc
6481 agccccttca atgagtgagg tggccctcgt cagatacatc aacccggaca ctggtcggtc
6541 actgtttgag gccaagctcc acagagctgg tttcatgaca gtctcgagca acaccagtgc
6601 cccggtggtt gtgcctgcca acggatactt cagatttgat tcttgggtga accaattcta
6661 ttctctcgcc cccatgggaa ctgggaatgg gcgtagaagg gttcaataat ggctggagct
6721 tttgtagctg gtcttgcagg ggacgtgctc agcaatgggc ttagttcatt aatcaatgca
6781 ggtgctaatg caataaatca gagggcagaa tttgatttta atcagaaatt gcagcaaaat
6841 tcttttaatc atgataagga gatgttgcag gctcagattc aggcaactaa gcagctgcag
6901 gcagacatga tggctataaa acaaggggtc ttgaccgctg gcggcttttc ccctgctgat
6961 gcagccagag gtgctgtgaa cgcgcctatg acacaagcgc tggattggaa tggtacaagg
7021 tattgggcac caaactccat gaggaccaca tattattctg gaaaattcac atcaaccgtc
7081 ccagtgaggc aggccgactt ccagcacacc caaagccggc cttcgagtgg ctcctctgtg
7141 tcttcctttg ccactcagtc ttcaaggcca actctgacca caaccactgg ttcctcacat
7201 ggcacagtct catcaaattc aactcgcagc acaagcctct cccaatcaac ggtctccaga
7261 gctacatcta ggactggtga gtgggttaga gatcaaaata gaaatttgga accctacatg
7321 catggtgcct tacagacagc ctttgtcacc ccaccttcca gcagggcatc tgacgggaca
7381 gtctcaaccg tcccgaaagg tgttttggac tcctggacac ctgcgtttaa cacccgcagg
7441 cagccgcttt ttgcacacct ccgtaagagg ggggagtcac aagcttag
//