Typing tool
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Typing tool
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Complete norovirus genomes
| OL336387 | GII.4 Sydney | |
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| GII.P16 |
ORF1: 1..5047
ORF2: 5028..6650
ORF3: 6650..7418
LOCUS OL336387 7418 bp RNA linear VRL 19-NOV-2021
DEFINITION Norovirus GII isolate 20153072 nonstructural polyprotein (ORF1)
gene, partial cds; VP1 (ORF2) gene, complete cds; and VP2 (ORF3)
gene, partial cds.
ACCESSION OL336387
VERSION OL336387.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7418)
AUTHORS Li,W., Yan,H., Shen,L., Liu,B., Tian,Y., Wang,Y., Jia,L., Gao,Z.
and Wang,Q.
TITLE Emergence of GII.4[P16] Noroviruses Associated Gastroenteritis in
Beijing, China, 2019-2021
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7418)
AUTHORS Li,W., Yan,H., Shen,L., Liu,B., Tian,Y., Wang,Y., Jia,L., Gao,Z.
and Wang,Q.
TITLE Direct Submission
JOURNAL Submitted (02-NOV-2021) Institute for Infectious Disease and
Endemic Disease Control, Beijing Center for Disease Prevention and
Control, Dongcheng District, No. 16 Hepingli Middle Street,
Beijing, Beijing 100013, China
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7418
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="20153072"
/isolation_source="stool specimen"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="China"
/collection_date="Oct-2020"
/note="genotype: GII.P16-GII.4"
gene <1..5047
/gene="ORF1"
CDS <1..5047
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="UEA14130.1"
/translation="DKEKSSGEGLFTNMSSTLKKALGARPKQPAPRDEPQKPPRPPTP
ELVKRIPPPPPNGEEEEEPVIRYEVKSGISGLPELTTVPQSDVANTAFSVPPLSLREN
REAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAISMARVELTPLSLYWRVV
YTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLNDSWLSRRMVQRTTGFFRP
YQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLIGKIKPLNILNILATCDWT
FAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAVELVPVVMGGIGLV
LGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKEEANELAMVRAIED
AVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLSTKSASPDIVGTINALLA
RIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLAREVARKVASTLTGDQRVGL
IPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELADTCPLTLNCDRIENKGKVF
DSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAKRDFPGQPDMWKDAF
KPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGLLHERMDEFELQGP
TITTFNFDRNRITAFRQLAAENKYGLVDTMKVGNQLKGVKTMEELKQAIRNVTIKRCR
IIYGGSTYDLESDGKGKVLVEKVKNTSIQTNNELAGALHHLKHARIRYYVKCVQEAVY
SIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESETKEEAPKSEDDEFVISSKDIKE
EGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRDRYYEEL
AIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVTGSEIRRRNPDDFKPKGK
LWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPSLFITSTHVIPAGITEAF
GVPIKQIQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEGTVATVLIKRPTGELMPLA
ARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDCGCPYIYKRGNDYIVIGV
HTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGPGGAPKLSTKTKFWRSSN
SPLPPGTYEPAYLGGRDPRVRGGPSLQQVMRDQLKPFTEPRGKPPRPSVLEAAKQTII
NVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHARKNEFWNGETFTGKLADQASKANL
MFEEGKHMTPVYTAALKDELVKTEKIYGKIKKRLLWGSDLSTMIRCARSFGGLMDEMK
AHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDSTQQRAVLAAALEIMVRF
SAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCTSQWNSITHWLLTLCALSE
VTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTAKLKEYGLKPTRPDKTEGPLII
SEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPNHEDPNETMIPHSQRPIQ
LMALLGEASLHGPSFYSRISKLVITELKEGGMDFYVPRQEPMFRWMRFSDLSTWEGDR
NLAPNFVNEDGVE"
mat_peptide <1..943
/gene="ORF1"
/product="p48"
mat_peptide 944..2041
/gene="ORF1"
/product="NTPase"
mat_peptide 2042..2572
/gene="ORF1"
/product="p22"
mat_peptide 2573..2971
/gene="ORF1"
/product="VPg"
mat_peptide 2972..3514
/gene="ORF1"
/product="Pro"
mat_peptide 3515..5044
/gene="ORF1"
/product="RdRp"
gene 5028..6650
/gene="ORF2"
CDS 5028..6650
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="UEA14131.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVNICTFRGDVTHITGSHNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGML
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTNHDFEANQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAV"
gene 6650..>7418
/gene="ORF3"
CDS 6650..>7418
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="UEA14132.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMRVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARITTYSSGHFSTPQPSGALPGRANLRDAVPARGPSTKSS
NSSATTSVYSNQTTSTRLGSTAGSGTSVSSLPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPL"
ORIGIN
1 cgacaaggaa aaatcttcag gtgaaggctt attcacaaat atgtcttcca ccttaaagaa
61 agccctcggg gctaggccca aacagcctgc cccgagagac gaaccacaaa agcccccaag
121 accaccaact cccgagttgg tcaagaggat accccctcct ccacctaatg gcgaagaaga
181 agaagaacca gtcattaggt atgaggttaa gagtgggatc tctggcctgc ccgagctcac
241 aacagttccc caatcggacg tggccaatac agcatttagt gttccaccac tgagcttgag
301 agaaaacagg gaggccaagg aaccgctaac aggggcaata ctagagatgt gggatggaga
361 gatataccac tatggcctgt acgtggagaa aggcttagtg ttgggtgtgc acaaaccacc
421 tgcagccata agcatggcaa gagtggagtt gacgccgctg tcattgtact ggcgtgtggt
481 gtacactccc caatacctca tctcccctga aactctcagg aggctcaacg gagaggcgtt
541 tccttacacc gctttcgaca acaactgcta tgccttttgt tgctgggtgt tagacctcaa
601 tgactcatgg cttagcagga ggatggtgca aagaacaacg ggcttcttca ggccttacca
661 agagtggaat agaaaaccct tgcctactat ggatgattcc aaaataaaga aggtagcaaa
721 tatattccta tgttcattgt ccacattatt caccagaccc ataaaagacc tcataggaaa
781 aatcaaacca ctaaacatat tgaacatctt ggcaacgtgt gactggacgt ttgccggaat
841 agtggagtct ctgatattgc ttgccgagct cttcggagtt ttctggacac ccccagatgt
901 gtctgctatg atcgctccct tactcgggga ctacgagtta caagggccag aagacctcgc
961 cgttgaactc gtacctgtgg taatgggagg gattggtttg gtgttgggat tcaccaaaga
1021 gaaaatcggc aaaatgttgt cctcagcagc atcaacactc agggcttgta aagatcttgg
1081 tgcctatggc ttagagatac tcaaattggt catgaagtgg ttcttcccaa agaaagagga
1141 ggccaatgaa ctagccatgg tgagggccat agaggatgcc gtgctagatc ttgaggcaat
1201 agagaataac cacatgacaa ccctgttgaa agacaaagac agcttagcaa catacatgaa
1261 aacactggac atggaggagg agaaagccag aaggttatcc acaaaatctg catcccctga
1321 catagttggg acaatcaacg ccctgctggc tcgaatagca gccgccaggt cattagtcca
1381 cagggccaag gaagagctgt ctagcaggat aagaccagta gttgttatga tatctggcaa
1441 accaggaata ggcaaaactc atctggccag ggaggtggca agaaaggtgg catccactct
1501 cacaggggac caaagagtcg gactcatacc aagaaacggt gtggaccatt gggatgcata
1561 taaaggtgag agagtcgtgc tgtgggacga ttatggcatg agtaacccca ttcatgatgc
1621 tctccgcata caagaattgg ctgatacgtg tccccttacc ttaaattgtg acagaattga
1681 aaataaggga aaagtttttg acagtgaagt cataataatt acaacaaacc ttgccaaccc
1741 agccccactt gattatgtca actttgaggc ctgttccagg agaattgatt tcctggtgta
1801 cgctgaggca ccagaagtag aaaaggcaaa acgggatttt cctggtcagc cagatatgtg
1861 gaaggacgcc ttcaagccgg acttttcaca catcaagcta cagcttgcac ctcagggcgg
1921 ctttgacaag aatggcaata ccccacatgg gaaaggagtg atgaagaccc tcactaccgg
1981 ttctctgatt gcccgtgcat caggcctact gcatgagagg atggatgaat ttgaactcca
2041 aggtcccaca atcaccactt tcaatttcga ccggaataga atcacagcat tcagacaatt
2101 ggctgcagaa aacaagtatg gactggtgga caccatgaaa gttggcaacc aactaaaagg
2161 agtgaaaacc atggaagaac tcaaacaagc aatcagaaat gtgaccatca agaggtgccg
2221 gatcatctac ggtggttcca cgtatgacct tgaatctgat ggtaagggca aagttttggt
2281 ggaaaaggtc aagaacacct ctatacaaac caacaacgag ttggccgggg ccttgcacca
2341 tcttaaacat gcccgaatca ggtactatgt caaatgtgtg caagaagcag tctattccat
2401 catacaaatt gccggcgctg cgtttgtcac cacgcgcatt gcacgccgca tgaacataca
2461 agaactctgg tcgaagccac aattagatca aaatgaatca gagactaagg aagaggcccc
2521 caagtcagaa gatgacgagt tcgtcatatc ttctaaggat atcaaggagg aaggaaagaa
2581 gggcaaaaac aaaactggcc gtggcaagaa acacactgca ttctccagca agggcttgag
2641 cgatgaggag tatgacgagt acaagaggat aagagaagag agaaacggga agtactctat
2701 agaggaatat cttcaagaca gagacaggta ctatgaggag ctcgccattg ccaaggccac
2761 ggaagaagac ttctgtgaag aggaggaaat caaaatccgt cagagaattt tccgtcccac
2821 caggaaacaa agaaaggaag agagggccac attagggctg gtaacaggtt cagaaatcag
2881 aagaagaaac cctgatgatt tcaaacccaa agggaagctt tgggccgatg acaacagaag
2941 tgttgactac aatgagaaac tggactttga ggccccccca agcatatggt ctagaattgt
3001 gagctttggt tctggctggg gcttctgggt atcaccaagc ctgttcataa catcaaccca
3061 tgttatccct gcaggcataa cagaagcatt tggagtcccc atcaaacaaa tccagattca
3121 caaatcaggt gaattttgcc gattcagatt cccaaaacca attagaccag atgtgacagg
3181 aatgatcttg gaagaaggtg cgcctgaagg caccgtggca actgtgctca tcaaacgccc
3241 caccggagag ctcatgcctc ttgcagccag aatgggaaca cacgcaacca tgaagattca
3301 aggccgcatg gttggcggac agatgggcat gttgctcact ggatcaaatg ctaaaggaat
3361 ggatttggga acaactcctg gtgactgtgg ctgcccttac atctataaaa ggggcaatga
3421 ctatatagtc attggggtac acactgcagc agcccgtggt ggaaacaccg tcatctgtgc
3481 cacacaggga agtgagggtg aggcaactct tgaaggtgga gatgacaaag gaacatactg
3541 tggggcaccc attctaggcc ctgggggtgc accaaaattg agcaccaaaa ccaaattttg
3601 gaggtcatcg aactcgcccc ttccaccagg gacatatgag cctgcctacc tcggtggccg
3661 tgacccgcgt gttaggggtg ggccctcctt acagcaggta atgagagacc aattgaagcc
3721 attcactgaa cccaggggca aacctccaag accaagtgtt ttggaagcag ccaaacaaac
3781 cattatcaat gtcctcgaac aaaccctgga tcctccacaa aaatggacat acgcacaggc
3841 gtgtgcctca cttgacaaaa ccacctccag cgggcatcca caccacgccc gaaagaatga
3901 attctggaat ggtgagacct tcactggtaa attggcagac caagcatcaa aagcaaacct
3961 aatgtttgag gaagggaaac acatgacacc agtgtataca gcagcactca aggacgagct
4021 agtcaagact gagaaaatct atggaaagat caagaagaga ctgctctggg gctctgactt
4081 gtccaccatg atccggtgcg ctaggtcatt tggtgggctc atggacgaga tgaaggcaca
4141 ctgcatatca ctcccagtac gagttggcat gaatatgaat gaagatggcc caataatatt
4201 tgagaaacat tccagataca aatatcacta tgatgcagac tactctcgct gggattcaac
4261 acaacagagg gcagtattag cagcagcctt agaaatcatg gtcagattct ctgcagaacc
4321 acaattggca caaatagtcg ctgaggatct actagcccct agtgtagtag atgtaggaga
4381 ctttaaaatc acaataaatg aagggcttcc atctggtgtg ccatgcactt ctcaatggaa
4441 ctccataaca cactggctgc taactctctg tgccttgtct gaagtcacca aactgtcccc
4501 tgacattata caagcaaatt ccatgttctc attttacggt gatgacgaga ttgtcagcac
4561 cgacataaaa ttggaccctg aacagttgac cgccaagttg aaggagtacg gcctgaaacc
4621 aactcgccca gacaagaccg agggacccct gatcatcagt gaagatttga acggactcac
4681 tttcctccga aggacggtga ctcgtgaccc agctggatgg tttggaaaac tggaccaaag
4741 ttcaattttg aggcagatgt actggactag aggaccaaat catgaagacc ccaatgagac
4801 aatgataccc cattctcaga gacccataca gctcatggca ctgcttggtg aagcctctct
4861 tcacggaccc tctttctaca gtagaatcag taaattggtc ataactgaac ttaaagaagg
4921 tgggatggac ttttacgtgc caaggcagga acccatgttc aggtggatga ggttttctga
4981 cttgagcacg tgggagggcg atcgcaatct ggctcccaat tttgtgaatg aagatggcgt
5041 cgagtgacgc caacccatct gatgggtccg cagccaacct cgtaccagag gtcaacaatg
5101 aggttatggc tttggagccc gttgttggtg ccgctattgc ggcacctgta gcgggccaac
5161 aaaatgtaat tgacccctgg atcagaaaca attttgtaca agcccctggt ggggagttca
5221 cagtatcccc tagaaatgct ccaggtgaaa tactatggag cgcgccccta ggccctgacc
5281 taaatcccta cctatcccat ttagccagaa tgtacaatgg ttatgcaggt ggttttgaag
5341 tgcaggtaat tctcgcgggg aacgcgttca ccgccgggaa gattatattt gcagcagtcc
5401 caccaaattt tccaactgaa ggtttaagcc ctagccaggt cactatgttc ccccacataa
5461 tagtagatgt tagacaattg gaacctgtgc tgatcccctt acccgatgtt aggaataatt
5521 tctatcatta caatcagtca aatgattcca ctattaagtt gatagcaatg ttgtacacac
5581 cacttagggc taataatgct ggggatgatg ttttcacagt ttcgtgccga gttctcacga
5641 gaccatcccc cgattttgat ttcatatttt tagtaccacc cacagttgag tcaagaacta
5701 aaccattctc tgtcccagtt ttaactgttg aggagatgac caattcaaga ttccccatcc
5761 ctttggaaaa gttgtttaca ggccccagca gtgcatttgt cgttcaacca caaaacggca
5821 gatgcacaac tgatggcgtg cttctaggca ccacccaact ttctcctgtc aacatctgca
5881 ccttcagagg ggatgtcact cacatcacag gtagtcacaa ctacactatg aatttggctt
5941 ctcaaaattg gaacaactat gatccaacag aagaaatccc agcccctcta ggaactccag
6001 attttgtggg gaagattcaa ggcatgctca cccagaccac aaggacagat ggttcaacac
6061 gcggtcacaa agctacagtg tacactggga gcgccgactt tgctccaaaa ctgggtagag
6121 ttcaatttga gactgacaca aaccatgatt ttgaagccaa tcaaaacaca aagttcaccc
6181 cagtcggtgt cattcaagat ggtagcacca cccatcgaaa cgaaccccag cagtgggtgc
6241 tcccaagtta ctcaggcaga aatactcaca atgtacattt ggcccccgct gtagccccca
6301 cctttccggg tgagcaactt ctcttcttta gatccaccat gcccggatgc agcgggtacc
6361 ccaacatgga tttggactgt ctgctccccc aggaatgggt gcagtacttc taccaagagg
6421 cagccccagc acaatctgat gtggctctgc taagatttgt gaatccagac acaggtaggg
6481 ttttgtttga gtgcaagctt cacaaatcag gctatgttac agtggctcac actggccaac
6541 atgatttggt tatccccccc aatggttact ttaggtttga ttcctgggtc aaccagttct
6601 acacgcttgc ccccatggga aatggaacgg ggcgtagacg tgcagtataa tggctggagc
6661 tttctttgct ggattggcat ctgatgtcct tggctctgga cttggttccc ttatcaatgc
6721 tggggctggg gccatcaacc aaaaggttga gtttgaaaat aacagaaaat tgcaacaagc
6781 atcctttcaa tttagcagca atttgcaaca ggcttccttt caacatgata aagagatgct
6841 ccaagcacaa attgaggcca ccaaaaagct gcaacaggaa atgatgagag ttaagcaggc
6901 aatgctccta gagggtgggt tctctgagac agatgcagcc cgcggggcaa ttaacgcccc
6961 catgacaaag gctttggact ggagcgggac aaggtactgg gctccagatg ctagaattac
7021 aacatacagt tcaggccact tttccactcc tcaaccatcg ggggcactgc caggaagagc
7081 taatcttagg gatgctgtcc ctgctcgggg accctccacc aaatcttcta actcttctgc
7141 taccacttct gtgtactcaa atcaaactac ttcaacgaga cttggttcta cagctggttc
7201 tggaaccagt gtctcgagcc tcccgtcgac tgcaaggact aggagctggg ttgaggatca
7261 aaataggaat ttgtcacctt tcatgagggg ggcccacaac atatcatttg tcaccccacc
7321 atctagcaga tcctccagcc aaggcacagt ctcaaccgtg cctaaagaaa ttttggactc
7381 ctggactggc gctttcaaca cgcgcaggca gcctctct
//