Typing tool
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Typing tool
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Complete norovirus genomes
| OL336382 | GII.4 Sydney | |
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| GII.P16 |
ORF1: 1..4988
ORF2: 4969..6591
ORF3: 6591..7334
LOCUS OL336382 7334 bp RNA linear VRL 19-NOV-2021
DEFINITION Norovirus GII isolate 19121200 nonstructural polyprotein (ORF1)
gene, partial cds; VP1 (ORF2) gene, complete cds; and VP2 (ORF3)
gene, partial cds.
ACCESSION OL336382
VERSION OL336382.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7334)
AUTHORS Li,W., Yan,H., Shen,L., Liu,B., Tian,Y., Wang,Y., Jia,L., Gao,Z.
and Wang,Q.
TITLE Emergence of GII.4[P16] Noroviruses Associated Gastroenteritis in
Beijing, China, 2019-2021
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7334)
AUTHORS Li,W., Yan,H., Shen,L., Liu,B., Tian,Y., Wang,Y., Jia,L., Gao,Z.
and Wang,Q.
TITLE Direct Submission
JOURNAL Submitted (02-NOV-2021) Institute for Infectious Disease and
Endemic Disease Control, Beijing Center for Disease Prevention and
Control, Dongcheng District, No. 16 Hepingli Middle Street,
Beijing, Beijing 100013, China
COMMENT ##Assembly-Data-START##
Sequencing Technology :: Sanger dideoxy sequencing
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7334
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="19121200"
/isolation_source="stool specimen"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="China"
/collection_date="Dec-2019"
/note="genotype: GII.P16-GII.4"
gene <1..4988
/gene="ORF1"
CDS <1..4988
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="UEA14115.1"
/translation="ALGARPKQPAPRDEPQKPPRPPTPELVKRIPPPPPNGEEEEEPV
IRYEVKSGISGLPELTTVPQPDVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIY
HYGLYVEKGLVLGVHKPPAAISMARVELTPLSLYWRVVYTPQYLISPETLRRLNGEAF
PYTAFDNNCYAFCCWVLDLNDSWLSRRMVQRTTGFFRPYQEWNRKPLPTMDDSKIKKV
ANIFLCSLSTLFTRPIKDLIGKIKPLNILNILATCDWTFAGIVESLILLAELFGVFWT
PPDVSAMIAPLLGDYELQGPEDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLR
ACKDLGAYGLEILKLVMKWFFPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDK
DSLATYMKTLDMEEEKARRLSTKSASPDIVGTINALLARIAAARSLVHRAKEELSSRI
RPVVVMISGKPGIGKTHLAREVARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLW
DDYGMSNPIHDALRIQELADTCPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYV
NFEACSRRIDFLVYAEAPEVEKAKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGFDKN
GNTPHGKGVMKTLTTGSLIARASGLLHERMDEFELQGPTITTFNFDRNRITAFRQLAA
ENKYGLVDTMKVGNQLKGVKTMEELKQAIRNVTIKRCRIIYGGSTYDLESDGKGKVLV
EKVKNTSIQTNNELAGALHHLKHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIARRMN
IQELWSKPQLDQNESETKEEAPKSEDDEFVISSKDIKEEGKKGKNKTGRGKKHTAFSS
KGLSDEEYDEYKRIREERNGKYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQ
RIFRPTRKQRKEERATLGLVTGSEIRRRNPDDFKPKGKLWADDNRSVDYNEKLDFEAP
PSIWSRIVSFGSGWGFWVSPSLFITSTHVIPAGITEAFGVPIKQIQIHKSGEFCRFRF
PKPIRPDVTGMILEEGAPEGTVATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQM
GMLLTGSNAKGMDLGTTPGDCGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEG
EATLEGGDDKGTYCGAPILGPGGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRV
RGGPSLQQVMRDQLKPFTEPRGKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACA
SLDKTTSSGHPHHARKNEFWNGETFTGKLADQASKANLMFEEGKHMTPVYTAALKDEL
VKTEKIYGKIKKRLLWGSDLSTMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPI
IFEKHSRYKYHYDADYSRWDSTQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVV
DVGDFKITINEGLPSGVPCTSQWNSITHWLLTLCALSEVTKLSPDIIQANSMFSFYGD
DEIVSTDIKLDPEQLTAKLKEYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAG
WFGKLDQSSILRQMYWTRGPNHEDPNETMIPHSQRPIQLMALLGEASLHGPSFYSRIS
KLVITELKEGGMDFYVPRQEPMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide <1..884
/gene="ORF1"
/product="p48"
mat_peptide 885..1982
/gene="ORF1"
/product="NTPase"
mat_peptide 1983..2513
/gene="ORF1"
/product="p22"
mat_peptide 2514..2912
/gene="ORF1"
/product="VPg"
mat_peptide 2913..3455
/gene="ORF1"
/product="Pro"
mat_peptide 3456..4985
/gene="ORF1"
/product="RdRp"
gene 4969..6591
/gene="ORF2"
CDS 4969..6591
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="UEA14116.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKIIFAAVPPNFPTEGLSPSQVTMFPHIIVDVRQLEPVLIPLPD
VRNNFYHYNQSNDSTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTTDGVLLGTT
QLSPVSICTFRGDVTHITGSHNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGML
SQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTNHDFEANQNTKFTPVGVIQDG
STTHRNEPQQWVLPSYSGRNTHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMDLD
CLLPQEWVQYFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAV"
gene 6591..>7334
/gene="ORF3"
CDS 6591..>7334
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="UEA14117.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMRVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARITTYNSGHFSTPQPSGALPGRANLRDAVPARGPSTKSS
NSSAATSVYSNQTTSTRLGSTAGSGTSVSSLPSTARTRSWVEDQNRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGA"
ORIGIN
1 aagccctcgg ggctaggccc aaacagcctg ccccgagaga cgaaccacaa aagcccccaa
61 gaccaccaac tcccgagttg gtcaagagga taccccctcc tccacctaat ggcgaagaag
121 aagaagaacc agtcattagg tatgaggtta agagtgggat ctctggcctg cccgagctca
181 caacagttcc ccaaccggac gtggccaaca cagcatttag tgttccacca ctgagcttga
241 gagaaaacag ggaggccaag gaaccgctaa caggggcaat actagagatg tgggatggag
301 agatatacca ctatggcctg tacgtggaga aaggcttagt gttgggtgtg cacaaaccac
361 ctgcagccat aagcatggca agagtggagt tgacgccgct gtcattgtac tggcgtgtgg
421 tgtacactcc ccaatacctc atctcccctg aaactctcag gaggctcaac ggagaggcgt
481 ttccttacac cgctttcgac aacaactgct atgccttttg ctgctgggtg ttagacctca
541 atgactcatg gcttagcagg aggatggtgc aaagaacaac gggcttcttc aggccttacc
601 aagagtggaa tagaaaaccc ttgcctacta tggatgactc caaaataaag aaggtagcaa
661 atatattcct atgttcattg tccacattat tcaccagacc cataaaagac ctcataggaa
721 aaatcaaacc actaaacata ttgaacatct tggcaacgtg tgactggacg tttgccggaa
781 tagtggagtc tctgatattg cttgccgagc tcttcggagt tttctggaca cccccagatg
841 tgtctgctat gatcgctccc ttactcgggg actacgagtt acaagggcca gaagacctcg
901 ccgttgaact cgtacctgtg gtaatgggag ggattggttt ggtgttggga ttcaccaaag
961 agaaaatcgg caaaatgttg tcctcagcag catcaacact cagggcttgt aaagatcttg
1021 gtgcctatgg cttagagata ctcaaattgg tcatgaagtg gttcttccca aagaaagagg
1081 aggccaatga gctagccatg gtgagggcca tagaggatgc cgtgctagat cttgaggcaa
1141 tagagaataa ccacatgaca accctgttga aagacaaaga cagcttagca acatacatga
1201 aaacactgga catggaggag gagaaagcca gaaggttatc cacaaaatct gcatcccctg
1261 acatagttgg gacaatcaac gccctgctgg ctcgaatagc agccgccagg tcattagtcc
1321 acagggccaa ggaagagctg tctagcagga taagaccagt agttgttatg atatctggca
1381 aaccaggaat aggcaaaact catctggcca gggaggtggc aagaaaggtg gcatccactc
1441 tcacagggga ccaaagagtt ggactcatac caagaaacgg tgtggaccat tgggatgcat
1501 acaaaggtga gagagtcgtg ctgtgggacg actatggcat gagtaacccc attcatgatg
1561 ctctccgcat acaagaattg gctgatacgt gtccccttac cttaaattgt gacagaattg
1621 aaaataaggg aaaagttttt gacagtgaag tcataataat tacaacaaac cttgccaacc
1681 cagccccact tgattatgtc aactttgagg cctgttccag gagaattgat ttcctggtgt
1741 acgctgaggc accagaagta gaaaaggcaa aacgggattt tcctggtcag ccagatatgt
1801 ggaaggacgc cttcaagccg gacttttcac acatcaagct acagcttgca cctcagggcg
1861 gctttgacaa gaatggcaat accccacatg ggaaaggagt gatgaagacc ctcactaccg
1921 gttctctgat tgcccgtgca tcaggcctac tgcatgagag gatggatgaa tttgaactcc
1981 aaggtcccac aatcaccact ttcaatttcg accggaatag aatcacagca ttcagacaat
2041 tggctgcaga aaacaagtat ggactggtgg acaccatgaa agttggcaat caactaaaag
2101 gagtgaaaac catggaagaa ctcaaacaag caatcagaaa tgtgaccatc aagaggtgcc
2161 ggatcatcta cggtggttcc acgtatgacc ttgaatctga tggcaagggc aaagttttgg
2221 tggaaaaggt caagaacacc tctatacaga ccaacaacga gttggccggg gccctgcacc
2281 atcttaaaca tgcccgaatc aggtactatg tcaaatgtgt gcaagaagca gtctattcca
2341 tcatacaaat tgccggcgct gcgtttgtca ccacgcgcat tgcacgccgc atgaacatac
2401 aagaactctg gtcgaagcca caattagatc aaaatgaatc agagactaag gaagaggccc
2461 ccaagtcaga agatgacgag ttcgtcatat cttctaagga tatcaaggag gaaggaaaga
2521 agggcaaaaa caaaactggc cgtggcaaga aacacactgc attctccagc aagggcttga
2581 gcgatgagga gtatgacgag tacaagagga taagagaaga gagaaacggg aagtactcta
2641 tagaggaata tcttcaagac agagacaggt actatgagga gctcgccatt gccaaggcca
2701 cggaagaaga cttctgtgaa gaggaggaaa tcaaaatccg tcagagaatt ttccgtccca
2761 ccaggaaaca aagaaaggaa gagagggcca cattagggct ggtaacaggt tcagaaatca
2821 gaagaagaaa ccctgatgat ttcaaaccca aagggaagct gtgggccgat gacaacagaa
2881 gtgttgacta caatgagaaa ctggactttg aggccccccc aagcatatgg tctagaattg
2941 tgagctttgg ttctggctgg ggcttctggg tatcaccaag cctgttcata acatcaaccc
3001 atgttatccc tgcaggcata acagaagcat ttggagtccc catcaaacaa attcagattc
3061 acaaatcagg tgaattttgc cgattcagat tcccaaaacc aattagacca gatgtgacag
3121 gaatgatctt ggaagaaggt gcgcctgaag gcaccgtggc aactgtgctc atcaaacgcc
3181 ccaccggaga gctcatgcca cttgcagcca gaatgggaac acacgcaacc atgaagattc
3241 aaggccgcat ggttggcgga cagatgggta tgttgctcac tggatcaaat gctaaaggaa
3301 tggatttggg aacaactcct ggtgactgtg gctgccctta catctataaa aggggcaatg
3361 actatatagt cattggggta cacactgcag cagcccgtgg tggaaacacc gtcatctgtg
3421 ccacacaggg aagtgagggt gaggcaactc ttgagggtgg agatgacaaa ggaacatact
3481 gtggggcacc cattctaggc cctgggggtg caccaaaatt gagcaccaaa accaaatttt
3541 ggaggtcatc gaacacgccc cttccaccag ggacatatga gcctgcctac ctcggtggcc
3601 gtgacccgcg tgttaggggt gggccctcct tacagcaggt aatgagagac cagttgaagc
3661 cattcactga acccaggggc aaacctccaa gaccaagtgt tttggaagca gccaaacaaa
3721 ccattatcaa tgtcctcgaa caaaccctgg atcctccaca aaaatggaca tacgcacagg
3781 cgtgtgcctc acttgacaaa accacctcca gcgggcatcc acaccacgcc cgaaagaatg
3841 aattctggaa tggtgagacc ttcactggta aattggcaga ccaagcatca aaagcaaacc
3901 taatgtttga ggaagggaaa cacatgacac cagtgtatac agcagcactc aaggacgagc
3961 tagtcaagac tgagaaaatc tatggaaaga tcaagaagag actgctctgg ggctctgact
4021 tgtccaccat gatccggtgc gctaggtcat ttggtgggct catggacgag atgaaggcac
4081 actgcatatc actcccagta cgagttggca tgaatatgaa tgaagatggc ccaataatat
4141 ttgagaaaca ttccagatac aaataccact atgatgcaga ctactctcgc tgggattcaa
4201 cacaacagag ggcagtatta gcagcagcct tggaaatcat ggtcagattc tctgcagaac
4261 cacaattggc acaaatagtc gctgaggatc tactggcccc tagtgtagta gatgtaggag
4321 actttaaaat cacaataaat gaagggctcc catctggtgt gccatgcact tctcaatgga
4381 actccataac acactggctg ctaactctct gtgccttgtc tgaagtcacc aaactgtccc
4441 ctgacattat acaagcaaat tccatgttct cattttacgg tgatgacgag attgtcagca
4501 ccgacataaa attggaccct gaacagttga ccgccaagtt gaaggagtac ggcctgaaac
4561 caactcgccc agacaagacc gagggacccc tgatcatcag tgaagatttg aacggactca
4621 ctttcctccg aaggacggtg actcgtgacc cagctggctg gtttggaaaa ctggaccaaa
4681 gttcaatttt gaggcagatg tactggacta gagggccaaa tcatgaagac cccaatgaga
4741 caatgatacc ccattctcag agacccatac agctcatggc actgcttggt gaagcctctc
4801 ttcacggacc ctctttctac agtagaatca gtaaattggt cataactgaa cttaaagaag
4861 gtgggatgga cttttacgtg ccaaggcagg aacccatgtt caggtggatg aggttttctg
4921 acttgagcac gtgggagggc gatcgcaatc tggctcccaa ttttgtgaat gaagatggcg
4981 tcgagtgacg ccaacccatc tgatgggtcc gcagccaacc tcgtaccaga ggtcaacaat
5041 gaggttatgg ctttggagcc cgttgttggt gccgctattg cggcacctgt agcgggccaa
5101 caaaatgtaa ttgacccctg gattagaaat aattttgtac aagcccctgg tggggagttc
5161 acagtatccc ctagaaatgc tccaggtgaa atactatgga gcgcgcccct aggccctgac
5221 ctaaatccct acctatccca tttagccaga atgtacaatg gttatgcagg tggttttgaa
5281 gtgcaggtaa ttctcgcggg gaacgcgttc accgccggga agattatatt tgcagcagtc
5341 ccaccaaatt ttccaactga aggtttaagc cctagccagg tcactatgtt cccccacata
5401 atagtagatg ttagacaatt ggaacctgtg ctgatcccct tacccgatgt taggaataat
5461 ttctatcatt acaatcagtc aaatgattcc actattaagt tgatagcaat gttgtacaca
5521 ccacttaggg ctaataatgc tggggatgat gttttcacag tttcgtgccg agttctcacg
5581 agaccatccc ccgattttga tttcatattt ttagtaccac ccacagttga gtcaagaact
5641 aaaccattct ctgtcccagt tttaactgtt gaggagatga ccaattcaag attccccatc
5701 cctttggaaa agttgtttac aggccccagc agtgcatttg tcgttcaacc acaaaacggc
5761 agatgcacaa ctgatggcgt gcttctaggc accacccaac tttctcctgt cagcatctgc
5821 accttcagag gggatgtcac tcacatcaca ggtagtcaca actacactat gaatttggct
5881 tctcaaaatt ggaacaacta tgatccaaca gaagaaatcc cagcccctct aggaactcca
5941 gattttgtgg ggaagattca aggcatgctc tcccagacca caaggacaga tggttcaaca
6001 cgcggtcaca aagctacagt gtacactggg agcgccgact ttgctccaaa actgggtaga
6061 gttcaatttg aaactgacac aaaccatgat tttgaagcca atcaaaacac aaagttcacc
6121 ccagtcggtg tcatccaaga tggtagcacc acccatcgaa acgaacccca gcagtgggtg
6181 ctcccaagtt actcaggcag aaatactcac aatgtacatt tggcccccgc tgtagccccc
6241 acctttccgg gtgagcaact tctcttcttc agatccacca tgcccggatg cagcgggtac
6301 cccaacatgg atttggactg tctgctcccc caggaatggg tgcagtactt ctaccaagag
6361 gcagccccag cacaatctga tgtggctctg ctaagatttg tgaatccaga cacaggtagg
6421 gttttgtttg agtgcaagct tcacaaatca ggctatgtta cagtggctca cactggccaa
6481 catgatttgg ttatcccccc caatggttac tttaggtttg attcctgggt caaccagttc
6541 tacacgcttg cccccatggg aaatggaacg gggcgtagac gtgcagtata atggctggag
6601 ctttctttgc tggattggca tctgatgtcc ttggctctgg acttggttcc cttatcaatg
6661 ctggggctgg ggccatcaac caaaaggttg agtttgaaaa taacagaaaa ttgcaacaag
6721 catcctttca atttagcagc aatttgcaac aggcttcctt tcaacatgat aaagagatgc
6781 tccaagcaca aattgaggcc accaaaaagc tacaacagga aatgatgaga gttaagcagg
6841 caatgctcct agagggtggg ttctctgaga cagatgcagc ccgcggggca attaacgccc
6901 ccatgacaaa ggctttggac tggagcggga caaggtactg ggctccagat gctagaatta
6961 caacatacaa ttcaggccac ttttccaccc ctcaaccatc gggggcactg ccaggaagag
7021 ctaatcttag ggatgctgtc cctgctcggg gaccctccac caaatcttct aactcttctg
7081 ctgccacttc tgtgtactca aatcaaacta cttcaacgag acttggttct acagctggtt
7141 ctggaaccag tgtctcgagc ctcccgtcga ctgcaaggac taggagctgg gttgaggatc
7201 aaaataggaa tttgtcacct ttcatgaggg gggcccacaa catatcattt gtcaccccac
7261 catctagcag atcctctagc caaggcacag tctcaaccgt gcctaaagaa attttggact
7321 cctggactgg cgct
//