Typing tool
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Typing tool
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Complete norovirus genomes
| OK376252 | GII.2 | |
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| GII.P16 |
ORF1: 4..5103
ORF2: 5084..6694
ORF3: 6694..7473
LOCUS OK376252 7517 bp RNA linear VRL 11-OCT-2021
DEFINITION Norovirus GII isolate CHN-GII4 nonstructural polyprotein (ORF1),
VP1 (ORF2), and VP2 (ORF3) genes, complete cds.
ACCESSION OK376252
VERSION OK376252.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7517)
AUTHORS Li,W., Tong,Y. and Mao,P.
TITLE Direct Submission
JOURNAL Submitted (05-OCT-2021) Fifth Medical Center, Chinese PLA General
Hospital, West Fourth Ring Middle Road, Beijing 100039, China
COMMENT ##Assembly-Data-START##
Assembly Method :: Newbler v. 2.3; CLC Genomic Workbench v.
9.0
Sequencing Technology :: Sanger dideoxy sequencing; Illumina;
IonTorrent
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7517
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="CHN-GII4"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="China"
/collection_date="Oct-2018"
/note="genotype: GII.2"
gene 4..5103
/gene="ORF1"
CDS 4..5103
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="UBX26718.1"
/translation="MKMASNDATVAVACNNNNDKEKSSGEGLFTNMSSTLKKALGARP
KQPAPRDKPQKPPRPPTPELVKRIPPPPPNGEEEKEPVIRYEVKSGISGLPELTTVPQ
PDVANTAFSVPPLSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAA
ISMARVELTPLSLYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLN
DSWLSRRMIQRTTGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLI
GKIKPLNILNILATCDWTFAGIVESLILFAELFGVFWTPPDVSAMIAPLLGDYELQGP
EDLAVELVPVVMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWF
FPKKEEANELAMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRL
STKSASPDIVGTINALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLAR
EVARKVASTLTGDQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELAD
TCPLTLNCDRIENKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEV
EKAKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIA
RASGLLHERMDEFELQGPTVTTFNFDRNRITAFRQLAAENKYGLVDTMKVGNQLKGVK
TMEELKQAIRNVTIKRCQIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHH
LKHARIRYYVKCVQEAVYSIIQIAGAAFVTTRIARRMNIQELWSKPQLDQNESETKEE
APKSEDDEFIISSKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNG
KYSIEEYLQDRDRYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLV
TGSEIRKRNPDDFKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSP
SLFITSTHVIPAGITEAFGVSIKQIQIHKSGEFCRFRFPKPIRPDVTGMILEEGAPEG
TVATVLIKRPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGD
CGCPYIYKRGNDYIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILG
PGGAPKLSTKTKFWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEAAKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHIRKNEFW
NGETFTGKLADQASKANLMFEEGKHMTPVYTAALKDELVKTEKIYGRIKKRLLWGSDL
STMIRCARSFGGLMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWD
STQQRAVLAAALEIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKITINEGLPSGVPCT
SQWNSIAHWLLTLCALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEQLTAKLK
EYGLKPTRPDKTEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGP
NHEDPKETMIPHSQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQE
PMFRWMRFSDLSTWEGDRNLAPNFVNEDGVE"
mat_peptide 4..999
/gene="ORF1"
/product="p48"
mat_peptide 1000..2097
/gene="ORF1"
/product="NTPase"
mat_peptide 2098..2628
/gene="ORF1"
/product="p22"
mat_peptide 2629..3027
/gene="ORF1"
/product="VPg"
mat_peptide 3028..3570
/gene="ORF1"
/product="Pro"
mat_peptide 3571..5100
/gene="ORF1"
/product="RdRp"
gene 5084..6694
/gene="ORF2"
CDS 5084..6694
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="UBX26719.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTLPILTLGELSNSRFPVSIDQMYTSPNEIISVQCQNGRCTLDGELQGTT
QLQVSGICAFKGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
IISQRDKHNSPGHNEPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDTEHFNQWVVPRYAGALAPSVAPVFPGERLLFFRSYIPLKGGYGNPAIDCLLP
QEWVQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAPVVVPAN
GYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6694..7473
/gene="ORF3"
CDS 6694..7473
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="UBX26720.1"
/translation="MAGAFVAGLAGDVLSNGLSSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPNSMRTTSYSGKFTSTAPVRQAGFQHTQSRPSSGSSVSSFATQSSRPTLTTTT
GSSHGTTSSNSTRSTSLSQSTVSRATSRTSEWVRDQNRNLEPYMHGALQTAFVTPPSS
RASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 ttaatgaaga tggcgtctaa cgacgctacc gttgccgttg cttgcaacaa caacaacgac
61 aaagaaaaat cttcaggtga aggcttattc acaaatatgt cttccacctt aaagaaagcc
121 ctcggggcta ggcccaaaca acctgccccg agagacaaac cacaaaagcc cccaagacca
181 ccaactcccg agttggtcaa gaggataccc cctcctccac ctaacggcga agaagaaaaa
241 gaaccagtca ttaggtatga ggttaagagt gggatctctg gtctgcccga gctcacaaca
301 gtcccccaac cggacgtggc caacacagca ttcagtgttc caccactgag cttgagagaa
361 aacagggagg ccaaggagcc gctaacaggg gcaatattag agatgtggga tggagagata
421 taccactatg gcctgtacgt ggagaaaggc ttagtgttgg gtgtgcacaa accacctgca
481 gccataagca tggcaagagt ggagctgacg ccgttgtcat tgtactggcg tgtggtgtac
541 actccccaat acctcatctc ccctgaaacc ctcaggaggc tcaacggaga ggcattccct
601 tacaccgcct ttgacaacaa ctgctatgcc ttttgctgct gggtgttaga cctcaatgac
661 tcatggctta gcaggaggat gatacaaaga acaacgggct tcttcagacc ttaccaagag
721 tggaacagaa aacccctgcc taccatggat gactccaaaa ttaagaaggt agcaaatata
781 ttcctatgtt cattgtccac attattcacc agacccataa aagacctcat aggaaaaatt
841 aaaccgttga acatattgaa tatcctggca acgtgtgact ggacttttgc cggaatagtg
901 gagtctctga tattatttgc tgaactcttc ggagttttct ggacaccccc agatgtgtct
961 gctatgatcg ctcccttact cggggactac gagttgcaag ggccagaaga cctcgccgtt
1021 gagctcgtac ctgtggtaat gggggggatt ggcttggtgt tgggattcac caaagagaaa
1081 attggcaaaa tgttgtcctc agcagcatca acactcaggg cttgcaaaga tcttggtgcc
1141 tatggcttag agatactcaa attggtcatg aagtggttct tcccaaagaa agaggaggcc
1201 aatgagctag ctatggtgag ggccatagag gatgctgtat tagaccttga ggcaatagaa
1261 aataaccaca tgacaaccct gttgaaagac aaagacagct tagcaacata catgaaaaca
1321 ctggacatgg aggaggagaa agccaggagg ttgtccacaa aatctgcatc ccctgacata
1381 gttgggacaa tcaacgccct gctggctcga atagcagcgg ccaggtcatt agtccacagg
1441 gccaaggaag agctatctag taggataagg ccagtagttg ttatgatatc tggcaagcca
1501 ggaataggca aaactcatct ggccagggag gtggcaagaa aggtggcatc cactctcaca
1561 ggggatcaaa gagtcggact cataccacga aatggtgtgg accattggga tgcatacaaa
1621 ggtgagagag tcgtgctgtg ggacgactat ggcatgagta accctattca tgatgctctt
1681 cgcatacaag aattggctga tacgtgtccc cttaccttaa attgtgacag aattgaaaat
1741 aagggaaaag tttttgacag tgaagtcata ataattacaa caaaccttgc caatccagcc
1801 ccacttgatt atgtcaactt tgaggcctgt tccaggagaa ttgatttcct ggtgtacgct
1861 gaggcaccag aagtagaaaa ggcaaaacgg gactttcctg gtcagccaga tatgtggaag
1921 gacgccttca agccggactt ttcacacatc aagctacagc ttgcacccca gggcggcttt
1981 gacaagaatg gcaacacccc acatgggaaa ggggtgatga agaccctcac taccggttct
2041 ctgattgccc gtgcatcagg cctactgcat gagaggatgg atgaatttga actccaaggc
2101 cccacagtca ccaccttcaa tttcgaccga aacagaatca cggcattcag acaattggct
2161 gcagaaaaca agtatggatt ggtggatacc atgaaagttg gcaatcaatt aaaaggagtg
2221 aaaaccatgg aagaactcaa acaagcaatc aggaatgtga ccatcaagag gtgccagatc
2281 atctacggag gttccacgta tgaccttgaa tctgatggca agggcaaagt tttggtggaa
2341 aaggtcaaga acacctctgt acagaccaat aacgagttgg ctggggccct gcaccatctc
2401 aaacatgccc gaatcaggta ctatgtcaaa tgtgtgcaag aagcagtcta ttccatcata
2461 caaattgccg gcgctgcgtt tgtcaccacg cgcatcgcac gccgcatgaa catacaagaa
2521 ctctggtcaa agccacaact agatcaaaat gaatcagaga ctaaggaaga ggcccccaag
2581 tcagaagatg acgaattcat catatcttct aaggacatca aggaggaagg aaagaagggc
2641 aaaaacaaaa ctggtcgtgg caagaaacac actgcattct ccagcaaggg cttgagcgat
2701 gaggagtatg acgagtacaa gaggataaga gaagagagaa atgggaagta ctctatagag
2761 gagtatcttc aagacagaga caggtactat gaggagctcg ccattgccaa ggccacggag
2821 gaagacttct gtgaagagga ggagatcaaa atccgtcaga gaattttccg tcccaccaga
2881 aaacaaagaa aggaagagag ggccacatta gggctagtaa caggttcaga aatcagaaaa
2941 agaaaccctg atgacttcaa acccaaaggg aagctgtggg ccgatgacaa caggagtgtt
3001 gactacaatg agaaactgga ctttgaggcc cccccaagca tatggtctag gattgtgagc
3061 tttggctctg gctggggctt ctgggtgtca ccaagccttt tcataacatc aactcatgta
3121 atccccgcgg gcataacaga agcatttgga gtctccatca aacaaatcca gatccacaaa
3181 tcaggcgaat tttgccgatt cagattccca aaaccaatta gaccagatgt gacaggaatg
3241 atcttggaag aaggtgcgcc tgagggcacc gtggcaactg tgctcatcaa acgtcccacc
3301 ggagagctca tgcctcttgc agccagaatg ggaacacacg caaccatgaa aattcaaggc
3361 cgcatggttg gcggacagat gggtatgttg ctcactggat caaatgctaa aggaatggac
3421 ttgggaacaa ctcctggtga ctgtggctgt ccttacatct ataaaagggg caatgactat
3481 atagtcattg gggtgcacac tgcagcagcc cgtggtggaa acactgtcat ctgtgccaca
3541 cagggaagcg agggtgaggc aactcttgag ggtggagatg acaaagggac atactgtggg
3601 gcacccattc taggccctgg gggtgcacca aaattgagca ccaaaaccaa attttggagg
3661 tcatcgaaca cgccccttcc accagggaca tatgagcctg cctacctcgg tggccgtgat
3721 ccgcgtgtta agggtgggcc ttccctgcag caggtgatga gagaccagtt gaagccattc
3781 actgaaccca ggggcaaacc tccaagacca agtgtattgg aagcagccaa acaaaccatc
3841 atcaatgtcc tcgaacaaac cctggaccct ccacaaaaat ggacatacgc acaggcgtgc
3901 gcctcacttg acaaaaccac ttccagcggg cacccccatc acatccgaaa gaatgaattc
3961 tggaatggtg agaccttcac tggtaaactg gcagaccaag catcaaaagc aaacctaatg
4021 tttgaggaag ggaaacacat gacaccagtg tacacagcag cactcaagga cgagctagtc
4081 aagactgaga aaatttatgg aaggatcaag aagagactgc tctggggctc tgacttgtcc
4141 accatgatcc ggtgcgctag gtcatttggt gggcttatgg acgagatgaa ggcacactgc
4201 atatcactcc cagttcgagt tggcatgaat atgaatgaag atggcccaat aatatttgag
4261 aaacattcca gatacaaata tcactatgat gcagactact ctcgttggga ttcaacacaa
4321 cagagggcag ttctagcagc agccttggaa atcatggtta gattctctgc agaaccacaa
4381 ttggcacaaa tagtcgctga ggatctgctg gcccctagtg tagtagatgt gggagacttt
4441 aaaatcacaa taaatgaagg gctcccttct ggtgtgccat gcacttctca atggaactcc
4501 atcgcacact ggctgctaac tctctgtgcc ttgtctgaag tcaccaaact atcccctgac
4561 attatacagg caaattccat gttctcattt tacggtgatg acgagattgt cagtaccgac
4621 ataaaattgg accctgaaca gttaaccgcc aaattgaagg agtacggcct gaaaccaacc
4681 cgcccagaca aaaccgaggg acccctgatt atcagtgaag atttgaacgg tctcactttc
4741 ctccgaagga cggtgactcg tgacccagct ggctggttcg gaaaactgga ccaaagctca
4801 attttgaggc agatgtattg gactagagga ccaaatcatg aagaccccaa agagacaatg
4861 ataccccatt cccaaagacc catacagctc atggcactgc ttggtgaagc ctctcttcac
4921 ggaccctctt tctacagtaa aatcagtaaa ttggtcataa ctgaactcaa agaaggtggg
4981 atggactttt acgtgccaag gcaggaaccc atgttcaggt ggatgaggtt ttctgacttg
5041 agcacgtggg agggcgatcg caatctggct cccaattttg tgaatgaaga tggcgtcgaa
5101 tgacgccgct ccatctactg atggtgcagc cggcctcgtg ccagaaagta acaatgaggt
5161 catggctctt gaacccgtgg ctggtgccgc cttggcagcc ccagtcaccg gtcaaacaaa
5221 tattatagac ccttggatta gagcaaattt tgtccaggcc cccaatggtg aatttacagt
5281 ctctccccga aatgcccctg gtgaagtgct actgaatcta gagttgggtc cagaattaaa
5341 tccttatctg gcacatttag caagaatgta caatgggtat gccggtggga tggaggtgca
5401 ggtcatgttg gctgggaacg cgttcacagc cggcaagttg gtcttcgccg ccgtgccacc
5461 ccacttcccg gttgaaaacc ttagcccaca gcaaatcacc atgttccctc atgtgatcat
5521 agatgtgagg accttggaac ctgttttgtt accactccct gatgttagga ataacttctt
5581 ccattataac cagaaagatg atcccaagat gagaattgtg gctatgcttt atacccccct
5641 caggtctaat ggttcaggtg atgatgtgtt tacagtctcc tgtagagtgt tgactagacc
5701 ttcccctgac tttgacttca catacctggt gccaccaaca gtggagtcta aaacaaagcc
5761 attcaccctc ccaatcctta cacttgggga actttccaat tccaggttcc cagtgtccat
5821 agaccagatg tacaccagtc ctaatgaaat tatatcagtg cagtgtcaaa atggtaggtg
5881 cacactggac ggggagctcc aagggacaac acaactccaa gtcagtggca tttgtgcttt
5941 caaaggtgaa gtgaccgccc acttgcatga caatgatcac ctatataatg tcaccatcac
6001 aaacttgaat gggtcccctt ttgatccctc cgaggatatc cctgcccctt tgggtgtgcc
6061 tgacttccag ggaagggtct ttggtatcat ctcccaaaga gataaacaca atagtcctgg
6121 gcataatgaa ccagcaaaca ggggacacga cgctgtggtc cctacttaca cagcacagta
6181 cactccaaaa cttggacaaa ttcaaattgg cacatggcaa actgacgacc ttacagtcaa
6241 ccaaccagtc aaattcaccc cagttggact caatgacact gaacacttta accaatgggt
6301 agtccctagg tatgctggtg cccttgcccc ttctgttgct ccagtatttc caggagagcg
6361 cctgctcttc ttcagatcat acattcccct caagggcggt tatggaaacc cagccattga
6421 ttgcctacta ccacaagagt gggtgcagca cttctatcag gaagcagccc cttcaatgag
6481 tgaggtggcc ctcgtcagat acatcaaccc ggacactggt cgggcactgt ttgaggccaa
6541 gctccataga gctggtttca tgacagtctc gagcaacacc agtgccccgg tggttgtgcc
6601 tgccaacggg tacttcagat ttgattcttg ggtgaaccaa ttttattctc ttgcccccat
6661 gggaactggg aatgggcgta gaagggttca ataatggctg gagcttttgt agctggtctt
6721 gcaggggacg tgctcagcaa tgggcttagt tcattaatca atgcaggtgc taatgcaata
6781 aatcagaggg cagaatttga ttttaaccaa aaattgcagc aaaattcttt taatcatgat
6841 aaggagatgt tgcaggctca gattcaggca actaagcagc tgcaggcaga catgatggct
6901 ataaaacaag gggtcttgac cgctggcggc ttttcccctg ctgatgcagc cagaggtgct
6961 gtgaacgcgc ccatgacaca ggcgctggat tggaatggca caaggtattg ggcaccaaac
7021 tccatgagga ccacatctta ttctggaaaa ttcacatcaa ccgccccagt gaggcaggct
7081 ggcttccagc acacccaaag ccggccttcg agtggctcct ctgtgtcttc ctttgccact
7141 cagtcttcaa ggccaactct gaccacaacc actggttcct cacatggcac aacctcatca
7201 aattcaactc gcagcacaag cctctcccaa tcaacggtct ccagagctac atctaggact
7261 agcgagtggg ttagggatca gaacagaaat ttggaaccct acatgcatgg tgccttacag
7321 acagcctttg tcaccccacc ttccagcagg gcatctgacg ggacagtctc aaccgtccct
7381 aaaggtgttt tggactcctg gacacctgcg tttaacactc gcaggcagcc gctttttgca
7441 cacctccgta agagggggga gtcacaagct tagtgaaaag gtgaaaattt gtttaggatt
7501 aattgatttc acctttt
//