Typing tool
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Typing tool
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Complete norovirus genomes
| MZ292794 | GII.8 | |
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| GII.P8 |
ORF1: 5..5101
ORF2: 5082..6695
ORF3: 6695..7468
LOCUS MZ292794 7494 bp RNA linear VRL 31-MAY-2021
DEFINITION Norovirus GII isolate Hu/US/2014/GII.8[P8]/CA-RGDS-1133
nonstructural polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes,
complete cds.
ACCESSION MZ292794
VERSION MZ292794.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7494)
AUTHORS Pan,C.-Y., Huynh,T., Padilla,T., Montmayeur,A.M., Chhabra,P.,
Barclay,L., Vinje,J., Wadford,D.A. and Morales,C.
TITLE Direct Submission
JOURNAL Submitted (25-MAY-2021) Viral and Rickettsial Disease Laboratory,
California Department of Public Health, 850 Marina Bay Parkway,
Richmond, CA 94804, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPades v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7494
/organism="Norovirus GII"
/mol_type="genomic RNA"
/strain="CA-RGDS-1133"
/isolate="Hu/US/2014/GII.8[P8]/CA-RGDS-1133"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="USA"
/collection_date="25-Jul-2014"
/note="Amplicon sequencing: first 35 nt does represent
primer sequence;
genotype: GII.8[P8]"
gene 5..5101
/gene="ORF1"
CDS 5..5101
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QVW09611.1"
/translation="MKMASNDASAAAGNFNIANNSENTPPPVKEEASVLSNVKVGFKK
ILGAVPKQPKPPEVKTKDQPRVLVNGKALEVPPPPPNGEDVVYYNSKDDTVHGLPNLT
TVSCEGENLPYTVPPLSEREHRAAPEPLPGTILEMWDGEFYHYAIYVSGGKAIGVHKP
PAAISLATIELTPISLYWRPVYVPNYLVHPDTLKSLAGEKFPYTAFSNNCYNFCCWVL
DLKDSWLNRRSITRTTGFFKPYQSWNKKPLPTVDDGKIKKVANAVLCALGSLFSKPIK
DLIGKLKPLNFLNLLASCDWTFSGVVETVILAELFGVFWTPPDVSNFIASLIGDFELQ
GPEDLAVELVPIIMGGIGMVLGFTAEKIGRMLSSAASTLRACRDLGNYALDILKLVMK
WFFPKKEEKAEMETLRAIEDAVLDMEAIGNNHLTALLKDRDSLLTYMKTLDLEEEKAR
KLSTKSSSPDIVGTINAILARIAAARSLLHRAKEEMYSRPRPVVVMISGRPGVGKTHM
ARHLAKSVASTMSGDQRVGLIPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALALQEL
ADTCPVTLNCDRIENKGKMFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAP
TIEKAKKDFPGQPDMWKEHFKADFSHLKLTLAPQGGFDKNGNTPHGKGTMKTLTQGSL
TARVAGLVHERKDEFQLQGGELQVYNFDTNKVSAFRKLAADNNYGFLETMGVGSSLKD
VKTVEDLKCALRSVSFKECEVIYRNVKYRISSDGCGKVSIEKLADNNSQTTREIITAV
TRLRQARARYYISCFQDLVYTLLQVAGASFVINRIVKKFNWERWVKAPETDEPTPSND
KPDTEEEWEIAPKDVDSEGKKGKNKKGRGRKHTAFSSKGLSDEEYDEFKRLREEKQGR
YTIEEYLQDRDRYYEELAVARATEENFCEEEEIKIRQRIFRPTKKQRKEERGVLGLVT
GADIRKRRPDDFQPKGKLWADDSRSVDYNEKIEFEAPPSVWSRIVPLGTGWGFWVSSN
LLITTTHVLPKGIKELFGVDIKQVQVHKSGEFCRFRFPKPVRPDVSGLVLEEGAPEGT
VCSVLIKRSTGEMIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDC
GCPYIYKRGNDIVVAGVHTAAARGGNTVICATQGPDGEAVLEGGEDHGTYCGAPILAP
GKAPKLSTKTKFWRSSPDSLPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEPR
GKPPRPSVLEEAKKTVMNVLEQTIEPAKPWTYSQACASLDKTTSSGSPHHIRKNEHWN
GESFTGPLADQASKANLMYEEGKHMDPMYTAALKDELVKTDKIYKKIKKRLLWGSDLG
TMVRCARAFGGLLDSMKESCISLPCRVGMNINEDGPLIFEKHSKYTYHYDADYSRWDS
TQQRAVLGAAMEVMVKFSAEPELAQVVAEDLLAPSRLDVGDFVISVQEGLPSGVPCTS
QWNSIAHWILTLSAMSEVSGLSPEVVQANSCFSFYGDDEIVSTDINLDPEKLTRKLRE
YGLVPTRPDKTEGPLVITQDLNGLTFLRRTIVRDPAGWFGKLDRDSILRQLYWTRGPN
HENPFESMIPHSQRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEA
MFRWMRFSDLSTWEGDRNLAPENVNEDGVE"
mat_peptide 5..1006
/gene="ORF1"
/product="p48"
mat_peptide 1007..2104
/gene="ORF1"
/product="NTPase"
mat_peptide 2105..2626
/gene="ORF1"
/product="p22"
mat_peptide 2627..3025
/gene="ORF1"
/product="VPg"
mat_peptide 3026..3568
/gene="ORF1"
/product="Pro"
mat_peptide 3569..5098
/gene="ORF1"
/product="RdRp"
gene 5082..6695
/gene="ORF2"
CDS 5082..6695
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QVW09612.1"
/translation="MKMASNDAAPSNDGAAGLVPEINHEVMAIEPVAGASLAAPVVGQ
LNIIDPWIRNNFVQAPAGEFTVSPRNAPGEFLLDLELGPELNPYLAHLSRMYNGHAGG
MEVQIVLAGNAFTAGKILFAVIPPGFPYENLSPAQLTMCPHVVVDVMQLEPILLPMPD
IRNTFFHYNQSNGPKLRLVAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFEFNFLVPP
SVESKTKVFTLPILKISEMTNSRFPIPVDQMYTSRNENIVVQPQNGRVTLDGELQGTT
TLQPVSICGFRGTLQTRLADQPNYTYQVHLENLDGSPVDPTDEVPAPLGTPDFQAQLF
GVISQRSSDNATRAHEARVNTNDPTFAPQIAQVRFKSPSHDFFDNEPIKFTPVGVSVD
SENSYNQWLLPRYGGHLTNNTHLAPSVSPMFPGEQILFFRSFMPGASGHTDGAIDCLL
PQEWVAHFYQEAATAQTDVALIRFVNPDTGRVLFEGKLHKQGFITISNSGDHPIVMPA
NGYFRFEAWVNQFYSLAPVGTGSGRRRIQ"
gene 6695..7468
/gene="ORF3"
CDS 6695..7468
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QVW09613.1"
/translation="MAGAFLAGLAGDVVTSGIGSLINAGANAVNQKIEYDFNRQLQEA
SFKHDKEMLNAQINATTKLQRDMIAIKQGVLTAGGFSPTDAARGSINAPTTKILDWNG
SRYWAPGSMRTTAYSGNFISQGVKQPTPIVRSVKPQVQQSPAPSSVYSVGSVRSQSTR
STQLTGSGTVSGAPTPSTTTTLSRTSEWVRSQNDRLSPFMGGALQTAFITPPSSKASS
SSGTVSTIPREILDSWTPAFNTRRQPLFAHIRKRGESRA"
ORIGIN
1 gtgaatgaag atggcgtcta acgacgcttc cgctgccgct ggcaacttta acattgccaa
61 caacagtgaa aacactcccc ctcccgttaa ggaagaggcg agtgtcctat ccaacgtaaa
121 agttggattc aagaaaatat tgggggctgt gcctaagcag cccaagccac cagaagtgaa
181 aaccaaagat caacccaggg tgttggtcaa tggtaaggcc ctggaggtgc cgcctccacc
241 accaaatggt gaagacgtgg tttactataa cagcaaggac gacactgtgc acggtctacc
301 aaatctaaca acagtcagct gtgaaggtga aaaccttccg tacacagttc ctcctctcag
361 cgagagagag cacagggcag caccagaacc attacctggc accatactag agatgtggga
421 tggtgaattc taccattatg cgatatatgt ctctggtggt aaggccatag gggtgcacaa
481 acccccagct gcaatcagcc ttgctaccat cgagcttaca cctatatcgc tttactggag
541 gcctgtttat gtccccaatt acttggtcca ccctgacaca ctcaagagct tagctggcga
601 aaaatttcca tacaccgcat ttagcaataa ttgttacaat ttctgttgct gggttcttga
661 cttgaaagac tcgtggctta accgcagatc aataactaga acaactggtt tcttcaagcc
721 ttatcaatcc tggaacaaga aaccacttcc gacggtggat gatggaaaaa tcaagaaagt
781 cgccaatgca gtcctgtgtg cccttggttc actattctca aaacctatta aggacttgat
841 cgggaagctg aagccattga atttcttgaa tctcctcgct tcgtgcgact ggaccttctc
901 cggagtggtt gagactgtca tactagctga actatttggt gtgttttgga ccccccccga
961 cgtgtcgaac ttcatcgcgt cactcatcgg ggacttcgag ctgcagggtc cagaggattt
1021 agctgtggag ttagtgccaa ttatcatggg cggcatcggg atggtgctgg gattcaccgc
1081 cgagaagatt ggtcgaatgc tatcatcagc tgcatcgacc cttagggcct gtagagacct
1141 aggtaactac gcccttgaca tacttaaatt ggtcatgaag tggttcttcc caaagaagga
1201 ggaaaaggca gagatggaga ccttgagggc catagaggat gctgtcttag atatggaggc
1261 aattggaaat aatcacctca ctgctctgtt gaaagacagg gacagcctcc taacctacat
1321 gaagactcta gacctcgaag aggaaaaggc gagaaagtta tccacaaaat catcttcccc
1381 tgacatcgtg ggtaccatca atgccatatt agccagaatt gccgcggcta ggtctctcct
1441 gcacagagcc aaagaggaaa tgtacagcag acctaggcct gtcgtggtga tgatatcagg
1501 aagaccaggg gttggtaaaa cccatatggc tagacacctc gccaagagtg tggcgagcac
1561 catgagcggt gaccaaaggg tgggccttat cccccgcaat ggagttgatc actgggatgc
1621 ctacagggga gaacgagttg tcttgtggga cgactacggc atgggtaacc cagtgaagga
1681 tgcccttgct ctgcaagaac tagcggacac ttgtccagtc accctcaatt gtgacaggat
1741 agagaataag ggaaagatgt ttgacagcga ggtaataatt ataacaacta atctggccaa
1801 ccctgccccg cttgattatg tcaactttga ggcttgttcc cgcagaattg acttcctcgt
1861 ctacgcagaa gccccaacca ttgagaaggc gaagaaggat tttcccgggc aaccagacat
1921 gtggaaggag cacttcaaag cagatttctc tcatctcaaa ctcacactgg ccccgcaagg
1981 cggttttgac aagaacggca acacaccaca tgggaagggg actatgaaga ccttaacaca
2041 gggttccctt acagcaagag tggctgggct tgtgcacgag aggaaagacg agttccagtt
2101 acagggtggg gagttgcagg tctacaactt tgacacaaac aaggtatcgg ctttcaggaa
2161 gcttgctgca gacaacaact atggatttct ggagacaatg ggagtcggct cctcactcaa
2221 ggacgtcaag acagtggaag atcttaaatg tgcccttaga agtgtcagtt tcaaagaatg
2281 tgaagtaatc tacaggaatg tcaagtaccg catatcatca gacggttgcg gtaaggtcag
2341 catagagaaa ctggcagata acaactccca aacaaccaga gaaattatca cggccgtcac
2401 tagactacga caggctcgtg ctaggtacta catcagttgt ttccaagacc tagtctacac
2461 actcctgcag gttgccggag cctcatttgt cattaataga atagttaaga agttcaactg
2521 ggaacgatgg gtcaaggctc cagaaacaga tgaacccaca ccaagtaatg acaagcccga
2581 cactgaagag gaatgggaga tcgcccccaa agatgtggac tctgagggta aaaaggggaa
2641 gaacaagaag ggcaggggac gtaagcacac tgcattctcc agcaaagggc ttagtgatga
2701 ggagtatgat gagttcaaaa gactaaggga agagaaacag ggccgctaca caatagagga
2761 gtacctccag gacagagacc ggtactatga agagctagca gtggcccggg ccactgaaga
2821 gaacttttgt gaagaggaag agataaagat caggcaaaga atattccgcc ccaccaaaaa
2881 gcagaggaag gaggagcgcg gggttctggg actcgtcaca ggagcagaca tcaggaaacg
2941 gagacccgat gacttccaac caaaaggaaa attgtgggca gatgattcta ggagcgtcga
3001 ctacaatgag aagatcgagt ttgaagctcc tcctagcgtc tggtcaagaa tcgtcccgct
3061 tgggactggt tggggattct gggtctcatc caacttacta attaccacca cacacgtgct
3121 gcccaaaggc atcaaagagc tttttggggt ggacatcaaa caagtccaag ttcacaaatc
3181 aggtgaattt tgcaggttca ggttcccaaa accagtgagg ccagatgtct ctgggttggt
3241 actagaagaa ggggcccccg aaggcacagt gtgctctgtt ctcatcaaga ggtcaacagg
3301 agagatgatc ccccttgcag ttaggatggg cacccacgcc tctatgaaga tccaggggcg
3361 cactgttggc ggccagatgg gcatgctgct cactggagcc aacgctaaga acatggattt
3421 gggtaccggc cccggggatt gtggttgccc gtacatatac aagaggggca atgacatcgt
3481 ggtggccggc gtccacacag cagcagcgcg cgggggcaac acggtcatct gcgcaaccca
3541 aggacctgat ggtgaggcag tgttggaagg gggagaggac cacggtactt actgtggagc
3601 cccaatactg gcccctggta aagcgccgaa gcttagcaca aagactaagt tttggcgctc
3661 atcccctgat tcccttcccc ctgggacgta tgaaccagct taccttgggg gcaaggaccc
3721 ccgtgtggag aaagggccgt cactccaaca agtgatgcga gaccaactca aacccttcac
3781 agaacccagg ggcaagccac ccaggccgtc agtgctggag gaagccaaga agacagtcat
3841 gaatgtactg gagcagacca tagaaccagc taagccatgg acctattctc aagcctgtgc
3901 ttcattggat aaaacaacat ccagtggcag tcctcaccac atcagaaaga atgaacactg
3961 gaacggggag tcttttactg ggcctcttgc agatcaagcc tcaaaagcca acctgatgta
4021 tgaggagggt aaacatatgg accctatgta cacagcagcc ctcaaggacg agctggtgaa
4081 aactgacaaa atctataaga aaatcaagaa gaggttgttg tgggggtctg atctggggac
4141 aatggtgagg tgtgctcgag cgtttggagg attgctcgac agcatgaaag agagttgcat
4201 ctccttgcct tgcagggttg gcatgaatat aaatgaagat ggaccactca tatttgaaaa
4261 acattccaaa tacacctatc attatgatgc tgattactct aggtgggact caacacagca
4321 gagggctgtc ctgggtgcag ccatggaggt aatggtgaag ttctccgctg agccggaact
4381 ggctcaggtg gttgccgaag acctccttgc gcccagccgt cttgacgtgg gtgacttcgt
4441 catctccgtt caagaaggtc ttccatcggg tgtcccctgc acgtcacagt ggaactcaat
4501 cgctcactgg atcctgactc tcagtgctat gtctgaggtc tctggtcttt cccctgaggt
4561 tgtgcaagcc aactcctgtt tctcattcta tggggatgat gagatagtca gcacagatat
4621 aaacctggac ccagaaaaac tcaccaggaa attgagggaa tatggtctcg tcccaacaag
4681 gccagacaaa actgagggcc cacttgtgat cactcaggat ttgaatggtc tcacattttt
4741 gaggcgaacc atagtgcggg accccgcagg ttggtttgga aaattggacc gtgattccat
4801 tctaaggcag ttatactgga ccagaggacc caatcatgag aacccctttg aaagcatgat
4861 tccccactcc cagagagcaa cccagttaat ggcccttctt ggggaagcct cgttgcatgg
4921 tccccagttt tacaagaagg tgagtaaaat ggtcatcaat gagatcaaga gtggtggtct
4981 ggagttttac gtgcccagac aggaggccat gttcagatgg atgagatttt cagacctcag
5041 cacgtgggag ggcgatcgca atctggctcc cgagaatgtg aatgaagatg gcgtcgaatg
5101 acgcagctcc atcgaatgat ggcgcggctg gcctcgtacc agagatcaac catgaggtca
5161 tggccataga gcctgttgca ggagcctctt tagcagcccc tgtcgtagga caacttaata
5221 taattgatcc ctggattaga aataattttg tacaagcccc tgctggagaa ttcactgttt
5281 cgcctagaaa tgctccaggt gaatttttgt tagatctaga gttaggccca gaattgaatc
5341 cttatcttgc tcacctttca cgcatgtata atgggcatgc aggtggtatg gaggtgcaga
5401 tagtgcttgc tgggaatgcg ttcacagcgg gcaaaatact gtttgcagtc ataccacctg
5461 gattccccta tgaaaatttg tcacctgcac aattgaccat gtgcccgcac gtagtggtgg
5521 atgtgatgca gcttgaacca atcttgctgc ccatgccaga catccgtaat acattcttcc
5581 attacaatca gagcaatggg ccaaaactca gattagtagc tatgctttac acacccctaa
5641 gggctaacaa tgctggtgat gatgtcttca cagtttcctg cagggttctg actcgtccat
5701 caccagattt tgaattcaat tttcttgtcc ccccatctgt tgaatctaag actaaagttt
5761 tcactcttcc aattcttaaa atatctgaga tgacaaattc aagatttccc ataccagttg
5821 accagatgta tactagtagg aatgaaaata tagttgttca accacagaat ggcagggtga
5881 cacttgatgg agagttacag ggcacaacca cactccaacc ggtgtccatt tgcggcttcc
5941 gagggacgct gcagaccagg ctagcagatc aaccaaatta cacataccaa gtgcaccttg
6001 agaatttgga cggctcaccc gtcgatccga cagatgaagt cccagccccc ctggggacgc
6061 cagattttca ggcccagcta tttggagtta tcagccaaag gagtagtgac aatgccacca
6121 gggcacatga ggccagggtc aacaccaacg atcctacctt cgcgccccag attgcccagg
6181 tgcgtttcaa atcaccatcc cacgacttct ttgacaatga acccattaag ttcacaccag
6241 ttggagttag tgttgatagc gaaaacagct acaaccaatg gctccttccc aggtatggtg
6301 ggcacctgac aaacaacacc cacctggccc cctctgtgtc cccaatgttc cccggcgagc
6361 agattctctt tttccgctcg ttcatgccag gcgccagtgg tcacactgat ggtgctattg
6421 actgcctttt accacaagag tgggttgccc acttctacca ggaggccgca actgcgcaaa
6481 cagacgtggc tctgattaga tttgtgaacc ccgacacagg cagagtgtta tttgaaggga
6541 agctacacaa gcagggtttt ataaccatct ccaacagtgg ggaccacccc attgttatgc
6601 ctgctaatgg atacttcagg tttgaggcat gggtcaatca attttactct ctcgcccccg
6661 tgggaactgg aagtgggcgt agaaggattc aataatggct ggagcttttc ttgcaggtct
6721 ggctggtgat gtggtgacct ctggcatcgg gtcgctcatc aatgcaggtg ctaatgcagt
6781 gaaccaaaag attgaatatg acttcaatag gcaacttcaa gaagcttctt ttaaacatga
6841 caaggagatg ttgaatgctc aaattaatgc cacaaccaaa ttgcagaggg acatgattgc
6901 catcaagcag ggggttttga ccgctggcgg cttttccccc actgatgctg caaggggttc
6961 catcaatgct ccaaccacca aaattcttga ctggaatgga tctaggtact gggcgccagg
7021 atcaatgaga acaacagcat actctggcaa tttcatatca cagggagtta agcagcccac
7081 acccattgtt agatctgtga aacctcaagt acagcaatct cctgcccctt cttctgttta
7141 ttctgtaggt tctgttagat cacaatcaac acgatcaact caattgacag ggtcagggac
7201 tgtatcaggg gcacccaccc cctcaacaac cacaacactg tccagaacaa gtgagtgggt
7261 gaggagccag aatgataggc tgagcccctt tatgggaggc gcacttcaga cagcttttat
7321 cacgccccca tcgagtaagg cttcatcctc atcaggaaca gtctcaacca ttcctagaga
7381 aattttggac tcctggactc ctgcatttaa cacacgcagg cagccgctct tcgctcacat
7441 acgtaagcga ggggagtcac gggcttagtg aaaagaatga tttggttaga ttat
//