Typing tool
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Typing tool
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Complete norovirus genomes
| MZ220330 | GI.1 | |
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| GI.P1 |
ORF1: 1..5370
ORF2: 5354..6946
ORF3: 6946..7584
LOCUS MZ220330 7659 bp RNA linear VRL 28-MAY-2021
DEFINITION Norovirus GI isolate Hu/US/2015/GI.1[P1]/CA-RGDS-1104 nonstructural
polyprotein (ORF1), VP1 (ORF2), and VP2 (ORF3) genes, complete cds.
ACCESSION MZ220330
VERSION MZ220330.1
KEYWORDS .
SOURCE Norovirus GI
ORGANISM Norovirus GI
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7659)
AUTHORS Pan,C.-Y., Huynh,T., Padilla,T., Montmayeur,A.M., Chhabra,P.,
Barclay,L., Vinje,J., Wadford,D.A. and Morales,C.
TITLE Direct Submission
JOURNAL Submitted (17-MAY-2021) Viral and Rickettsial Disease Laboratory,
California Department of Public Health, 850 Marina Bay Parkway,
Richmond, CA 94804, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: Geneious v. R10; SPades v. 3.6
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7659
/organism="Norovirus GI"
/mol_type="genomic RNA"
/strain="CA-RGDS-1104"
/isolate="Hu/US/2015/GI.1[P1]/CA-RGDS-1104"
/isolation_source="stool"
/host="Homo sapiens"
/db_xref="taxon:122928"
/country="USA"
/collection_date="29-Jul-2015"
/note="Amplicon sequencing: first 35 nt does represent
primer sequence;
genotype: GI.1[P1]"
gene 1..5370
/gene="ORF1"
CDS 1..5370
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QVK11254.1"
/translation="MMMASNDAIPTAASSENANNNSSIKSRLLARLKGVSGTTTPPNS
IQITNQNMALGLIGQAPAPKATAVEAPKQQRDRPPRTAAEVQQNLCWTEKPQDQNVKA
WDELDHTTKQQILDEHAEWFDAGGLGPSTLPSNHERHPNDDSGGHQVKWSAKEGVNLG
IDGLTTVPGPEWNMCPLPPADQRSTTPAVEPIIGDMIEFYEGHIYHYAIYIGQGKTVG
VHSPQAAFSITRITIQPISAWWRVCYVPQPKQRLTYDQLKELENEPWPYAAVTNNCFE
FCCQVMCLEDTWLQRKLISSGRFHHPTQDWSRDTPEFQQDSKLEMVRDAVLAAINGLV
SRPFKDLLGKLKPLNVLNLLSNCDWTFMGVVEMVVLLLELFGVFWNPPDVSNFIASLL
PDFHLQGPEDLARDLVPVVLGGIGLAIGFTRDKVSKMMKNAVDGLRAATQLGQYGLEI
FSLLKKYFFGGDQTEKTLKDIESAVIDMEVLSSTSVTQLVRDKQSARAYMAILDNEEE
KARKLSVRNADPHVVSSTNALISRISMARAALAKAQAEMTSRMRPVVIMMCGPPGIGK
TKAAEHLAKRLANEIRPGGKVGLVPREAVDHWDGYHGEEVMLWDDYGMTKIQEDCNKL
QAIADSAPLTLNCDRIENKGMQFVSDAIVITTNAPGPAPVDFVNLGPVCRRVDFLVYC
TAPEVEHTRKVSPGDTNALKDCFKSDFSHMKMELAPQGGFDNQGNTPFGKGVMKPTTI
NRLLIQAVALTMERQDEFQLQGPTYDFDTDRVSAFTKMARANGIGLVSMASLGKKLRG
VSTIEGLKNALLGYKIAKCSIQWQSRVYIIESDGSNVHIKEDKQALTPLQQTINTASL
AITRLKAARAVAYASCFQSAVTTILQMAGSALVINRAVKRMFGTRTAAMALEGPEKEH
NCRVHKAKEAGKGPIGHDDMIEKFGLCETEEEESEDQIQMTPNDAIPEGKNKGKTKKG
RGRKNNYNAFSRRGLSDEEYEEYKKIREEKNGNYSIQEYLEDRQRYEEELAEVQAGGD
GGIGETEMEIRHRVFYKSKSRKHQQEQRRQLGLVTGSDIRKRKPIDWTPPKNEWADDD
REVDYNEKINFEAPPTMWSRVTKFGSGWGFWVSPTVFITTTHVVPTGVKEFFGEPLTN
IAIHQAGEFTQFRFSKKIRPDLTGMVLEEGCPEGTVCSVLIKRDSGELLPLAVRMGAI
ASMRIQGRLVHGQSGMLLTGANAKGMDLGTIPGDCGAPYVHKRGNDWVVCGVHAAATK
SGNTVVCAVQASEGETALEGGDKGHYAGHEIVRHGNGPALSTKTKFWRSSPEPLPPGV
YEPAYLGGKDPRVQNGPSLQQVLRDQLKPFAEPRGRMPEPGLLEAAVETVTSMLEQTM
DTPSPWSYADACQSLDKTTSSGFPYHKRKNDDWNGTTFVRELGDQAAHANNMYENGKH
MKPIYTAALKDELVKPEKVYQKIKKRLLWGADLGTVIRAARAFGPFCDAIKPHVIKLP
IKVGMNTIEDGPLIYAEHAKYKNHFDADYTAWDSTQNRQIMTESFSIMSRLTASPELA
EVVAQDLLAPSEMDVGDYVIRVKEGLPSGFPCTSQVNSINHWIITLCALSEATGLSPD
VVQAMSYFSFYGDDEIVSTDIDFDPARLTQILKEYGLRPTRPDKTEGPIQVRRNVDGL
VFLRRTISRDAAGFQGRLDRASIERQIFWTRGPNHSDPSETLVPHTQRKVQLISLLGE
ASLHGEKFYRKISSKVIHEIKTGGLEMYVPGWQAMFRWMRFHDLGLWTGDRNLLPEFV
NDDGV"
mat_peptide 1..1194
/gene="ORF1"
/product="p48"
mat_peptide 1195..2283
/gene="ORF1"
/product="NTPase"
mat_peptide 2284..2886
/gene="ORF1"
/product="p22"
mat_peptide 2887..3300
/gene="ORF1"
/product="VPg"
mat_peptide 3301..3843
/gene="ORF1"
/product="Pro"
mat_peptide 3844..5367
/gene="ORF1"
/product="RdRp"
gene 5354..6946
/gene="ORF2"
CDS 5354..6946
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QVK11255.1"
/translation="MMMASNDAMSNVDGASGAGQLVPEANTSDPLAMDPVAGSSTAVA
TAGQVNPIDPWIINNFVQAPQGEFTISPNNTPGDVLFDLSLGPHLNPFLLHLSQMYNG
WVGNMRVRIMLAGNAFTAGKIIVSCIPPGFGSHNLTIAQSTLFPHVIADVRTLDPIEV
PLEDVRNVLFHNNDRNQQTMRLVCMLYTPLRTGGGTGDSFVVAGRVMTCPSPDFNFLF
LVPPTVEQKTRPFTLPNLPLSSLSNSRAPLPIGSMGISPDNVQSVQFQNGRCTLDGRL
VGTTPVSLSQVGKIRGTSNGTVINLTELDGTPFHPFEGPAPIGFPDLGGCDWHINMTQ
FGHSSQTQFDVDTTPETFVPHLGSIQAGGIGSGNYIGVLSWISPPSHPSGSQVDLWKI
PNYGSSVTEATHLAPSVFPPGFGEVLVFFMSKIPGPGAYNLPCLLPQEYISHFASEQA
PTVGEAALLHYVDPDTGRNLGEFKAYPDGFLTCVPNGSSSGPQQLPINGVFVFVSWVS
RFYQLKPVGTASSARGRLGLRR"
gene 6946..7584
/gene="ORF3"
CDS 6946..7584
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QVK11256.1"
/translation="MAQAIIGAIAASTAGSALGAGIQVGGEAALQSQRYQQNLQLQEN
SFKHDKEMIGYQVEASNQLLAKNLATRYSLLRAGGLSSADAARSIAGAPVTRIVDWNG
VRVSAPESSATTLRSGGFMSVPIPYASKQKQIQSSGISNPNYSPSSISRTTSWVESQN
SSRFGNLSPYHTEALNTVWLTPPGSTASSTLSSVPRGYFNTDRLPLFANNRR"
ORIGIN
1 atgatgatgg cgtctaacga cgctattcct actgctgcta gcagtgaaaa tgctaacaac
61 aacagtagta tcaagtctcg cctattggcg agacttaaag gtgtgagtgg aacaacgact
121 ccacctaatt ctatacaaat aactaaccaa aatatggctt tggggctgat tggccaggcc
181 ccagcaccaa aggccacggc cgtggaggcc cccaagcaac agagggatag gcctccgcgg
241 actgctgccg aagtccaaca aaacttatgt tggaccgaaa aaccgcaaga ccaaaatgtc
301 aaggcgtggg atgaactaga ccatacaaca aaacaacaga tacttgatga gcatgctgaa
361 tggtttgatg ctggtggttt gggcccaagc acactcccta gcaaccacga acgccaccca
421 aacgatgata gtggaggcca ccaagttaaa tggtcggcta aagagggtgt gaatctcgga
481 atagatggac tcactactgt tcccggaccc gagtggaaca tgtgcccgtt acccccagca
541 gatcaaagga gcacgacgcc tgcagtcgag cccataatag gtgacatgat cgagttttat
601 gaaggtcaca tctaccatta tgccatctat atcggtcaag gcaagacagt gggtgtccat
661 tctcctcaag cagcattctc aataacaaga atcaccatac aacctatatc agcatggtgg
721 cgggtatgct atgtcccaca gccaaaacag agacttacat atgatcaact caaagaattg
781 gagaacgaac catggccata cgccgcggtc accaataact gttttgaatt ctgttgccag
841 gttatgtgtc tagaagacac ttggctacaa agaaagctca tctcctctgg acgattccac
901 catccaaccc aggattggtc tcgtgacact ccagagttcc aacaagacag taaacttgag
961 atggtcagag atgcagtgtt agccgcgata aatgggttag tgtcgcggcc ctttaaggat
1021 ctcctaggca aacttaaacc tttgaatgtg ctcaacttgc tttcaaactg tgattggaca
1081 tttatggggg ttgtggaaat ggtggtcctt cttttggagc tttttggagt gttttggaat
1141 ccacccgatg tgtccaattt tatagcttca ctcctaccag attttcacct acagggccct
1201 gaagaccttg ctagagacct tgtgccagtg gtcttgggcg gtattggtct ggccatagga
1261 tttactaggg acaaggtgag taagatgatg aagaatgctg tcgacggact gcgggctgca
1321 acccagctcg ggcagtatgg cctggaaata ttctcactat taaagaagta cttctttggt
1381 ggagaccaga cagagaagac cctaaaagat atagaatcag ctgtcattga catggaggtg
1441 ttgtcatcca cctcagtgac ccagctcgtg agggataagc aatctgcgcg ggcttacatg
1501 gctatcttgg ataatgaaga agaaaaagct agaaagctgt ccgtcaggaa tgctgatcca
1561 cacgtggtat cttctaccaa tgctctcata tcccgaatat caatggctag agccgcccta
1621 gccaaggccc aggctgagat gactagcagg atgcgtcctg tagtcattat gatgtgtggg
1681 ccccctggca taggaaagac caaggcagcg gaacacctgg ccaaacggtt ggccaacgaa
1741 atacggcctg gcggcaaagt tggactagtc ccacgtgaag ctgtggacca ttgggatggt
1801 tatcatggtg aggaagtgat gttatgggat gactatggga tgaccaaaat acaggaggat
1861 tgcaacaaac tacaagccat agctgactcg gcccccctga cgctcaattg tgaccgaata
1921 gagaataaag ggatgcaatt cgtgtctgat gccatagtca taaccactaa tgcccctggc
1981 ccagcccccg tggactttgt caacctcgga cctgtctgtc gaagggtgga cttccttgtg
2041 tactgtacgg caccagaagt ggaacatacg aggaaagtta gccctggcga cactaatgca
2101 ctaaaggact gttttaaatc tgacttttct cacatgaaaa tggaactcgc cccccagggt
2161 ggttttgata accaagggaa caccccgttt ggcaagggtg taatgaaacc aaccaccata
2221 aataggttac taatccaagc tgtggcctta acaatggaga ggcaggatga gttccaactt
2281 caaggtccca cttatgactt tgacactgat agggtctctg catttacaaa gatggcccga
2341 gctaatggga taggtcttgt atccatggcc tccttaggca agaaattgcg tggggtttcc
2401 accattgaag gcttgaagaa tgcccttctg ggatacaaga tagcaaagtg cagcatacag
2461 tggcagtcaa gggtgtacat catagaatca gatggtagta atgtacacat caaggaggac
2521 aagcaggctc taaccccctt acaacagaca attaacacag cctccttggc tatcacacgg
2581 cttaaagcgg ctagagctgt ggcttacgcc tcatgcttcc aatctgctgt caccaccata
2641 ttacaaatgg cagggtccgc attggtcatc aatcgggcag tcaagcgcat gtttggtacc
2701 cgtacggcag ccatggcgct agagggacca gaaaaagaac acaattgcag ggttcataaa
2761 gctaaggaag ctgggaaggg gcctatagga catgatgaca tgatagaaaa gttcggcctg
2821 tgtgagactg aagaggaaga aagcgaagac caaatccaaa tgaccccaaa tgatgccatt
2881 ccagaaggga agaacaaagg taagaccaag aaaggccgcg gccgcaaaaa caattacaat
2941 gcattctctc gacgtgggct gagtgatgag gagtatgaag aatacaaaaa gatcagggaa
3001 gagaagaatg gtaattacag catacaagaa tatttggagg atcgtcaacg gtatgaggaa
3061 gagttggcag aggtccaagc aggtggcgac ggtggtatag gggagactga gatggagatt
3121 cgccacagag ttttctacaa atccaaaagc agaaagcacc aacaggaaca acgacgtcaa
3181 cttggcctgg taactggatc ggatatcagg aaacgcaagc ctattgattg gaccccacca
3241 aagaatgaat gggctgatga tgatagggaa gttgactata atgaaaagat caattttgag
3301 gcccccccaa caatgtggag ccgggttaca aagtttgggt caggatgggg cttctgggtc
3361 agtccaaccg tgttcattac caccacacat gtggtgccaa ctggcgtgaa ggaattcttt
3421 ggcgaacctc tcaccaatat agcaatccat caagcaggtg agttcacaca gttcaggttc
3481 tctaagaaga tacgccctga cctgacgggc atggtgttgg aggaaggctg tcctgaaggg
3541 acagtttgtt cagtcctgat caaacgagac tcaggcgagc ttctcccact ggctgtccgt
3601 atgggggcca ttgcctctat gaggatacag ggccgccttg ttcatggcca atcaggaatg
3661 ctactgacag gagcgaatgc aaaagggatg gaccttggaa ctataccagg ggactgtgga
3721 gcaccatacg tccacaagcg cggtaacgac tgggttgtgt gcggagtcca cgctgcagcc
3781 acaaaatcag gtaacactgt ggtctgtgct gtgcaggcta gtgaaggtga gaccgcgtta
3841 gaaggcggag acaaagggca ctatgcgggt catgaaattg taaggcacgg gaatggcccg
3901 gcattgtcaa ctaaaacaaa attctggaga tcctccccag agccattgcc ccctggagtt
3961 tatgagcctg catacctagg aggaaaggac ccacgtgtcc agaatggtcc ttccctccaa
4021 caggttctgc gtgaccaatt gaaacccttt gcagagcccc gtggccgcat gcctgaacct
4081 ggtttgctgg aggcggcggt cgagactgta acatccatgt tagaacaaac aatggacact
4141 ccaagcccat ggtcttatgc tgatgcctgt caatctcttg ataaaactac aagttcaggc
4201 tttccctacc acaaaaggaa gaatgatgat tggaacggta ctacctttgt cagggagctt
4261 ggtgatcagg ccgcacatgc taacaacatg tatgagaatg gcaaacacat gaaacccatc
4321 tacacagcag ctttgaagga tgagctagtc aaacccgaaa aggtctacca aaagatcaaa
4381 aagcgcctat tatggggtgc cgacctcgga actgtaatca gagctgcccg agcttttggc
4441 ccattctgtg atgctataaa gccgcatgtc atcaagctac caataaaggt tggcatgaac
4501 acaatagaag atggccccct gatttatgct gagcatgcca agtacaaaaa ccactttgat
4561 gcggattaca cagcatggga ctcaacacag aatagacaaa ttatgacaga atctttctcc
4621 attatgtcac gcctaacggc ctctcctgag ctggccgaag tcgtggccca agatttattg
4681 gcaccatctg agatggatgt gggtgactat gtcataagag ttaaggaagg cttaccatct
4741 gggttcccgt gtacttccca agtgaacagc ataaatcatt ggataattac cctctgtgca
4801 ctttctgaag ccactggtct gtcacctgac gtagtgcaag ccatgtcata cttctcattt
4861 tatggcgatg atgaaattgt gtcaactgac atagattttg acccagcccg cctcacccaa
4921 atccttaagg aatatggtct caggccaaca aggccagata aaactgaagg gccaatacag
4981 gtcaggagga atgtggatgg actagttttc ttgcgccgca ccatctcccg tgacgctgca
5041 gggttccagg gcaggctaga tagggcctca attgaacggc agattttctg gacccgcggg
5101 cccaaccatt cagacccttc agagacattg gtgccgcaca cccaaagaaa agtgcaattg
5161 atctcactct taggagaggc ttcactccat ggagaaaagt tctatagaaa gatttccagc
5221 aaagtcatac atgaaattaa gactggtggg ttggagatgt atgtcccagg gtggcaggcc
5281 atgttccgct ggatgcgctt ccatgacctc ggattgtgga caggagatcg caatcttctg
5341 cccgaattcg tgaatgatga tggcgtctaa cgacgctatg tcaaacgtgg atggcgccag
5401 tggcgctggt cagttggtac cggaggctaa tacttctgac ccccttgcaa tggatcctgt
5461 ggcaggttct tcgacggcgg ttgcgactgc tggacaagta aaccccattg atccttggat
5521 aattaataat tttgtgcaag ctccccaagg ggagttcaca atctctccaa ataatacccc
5581 cggtgatgtt ttatttgatc tgagtttagg tccccacctt aatcccttct tgctacatct
5641 gtcacaaatg tataatggtt gggttggcaa tatgagagtt aggattatgc tggccggcaa
5701 cgcctttact gcaggtaaga tcatagtttc ctgtatacct cctggttttg ggtcgcataa
5761 tcttactata gcacaatcaa ctctatttcc acatgtgatt gctgatgtta ggactctaga
5821 ccctattgaa gtacctttgg aagatgttag gaatgttctc tttcataata atgataggaa
5881 tcaacaaact atgcgccttg tgtgcatgtt atatacccct ctccgcactg gtggtggtac
5941 aggtgattcc tttgttgtgg cggggcgagt catgacctgc cctagtcctg attttaattt
6001 cttgttcttg gtccccccca cagtggagca gaaaactaga cctttcaccc ttccaaattt
6061 gcctttgagc tctttgtcta attcacgtgc tccactccca attggcagca tgggcatttc
6121 tccagacaat gttcagagtg tacaattcca aaatggtcgg tgcactttgg acggtcgttt
6181 ggttggcacc accccagttt cactgtccca ggttggtaag ataaggggta cttccaatgg
6241 tactgtcatc aaccttactg aattggatgg cacgcctttt cacccttttg aaggccctgc
6301 ccccattgga ttcccagatc tcggtggttg cgactggcat atcaacatga cacaatttgg
6361 ccactctagt cagacacaat ttgatgtgga taccacccct gaaacctttg tcccccattt
6421 aggatcaatc caggcaggtg gtattggtag tggcaattac attggtgttc tcagttggat
6481 ctccccccca tcacatcctt ctggttccca ggtagacctt tggaagatcc ccaattatgg
6541 gtcgagcgtt actgaggcaa cacacctggc cccatcagtg ttcccacccg gctttgggga
6601 agtgctggtt ttcttcatgt cgaagatacc agggcctggc gcctacaatc tgccctgcct
6661 gctgccacaa gagtacatct cacactttgc aagtgagcaa gcccccactg tgggtgaggc
6721 tgctctgctc cattatgttg accctgatac agggcggaac cttggggagt tcaaagcata
6781 ccccgatgga tttctcactt gtgtccccaa tggatccagc tcgggtccac aacagttacc
6841 aatcaatgga gtttttgttt ttgtctcttg ggtgtctagg ttctatcaat tgaagcctgt
6901 gggaactgcc agttcggcaa gaggtaggct tggattgcgc cgataatggc tcaagctata
6961 attggtgcaa ttgctgcctc cacagcgggc agtgcccttg gggcaggtat acaggttggt
7021 ggtgaggcag cactccaaag tcaaagatat caacaaaatc tgcaattgca agagaattcc
7081 tttaaacatg acaaagaaat gattggatat caagttgagg cttcaaatca attgctagcc
7141 aagaatcttg caaccagata ctcactcctt cgtgctggag gtctatccag tgctgatgca
7201 gcaaggtcca tcgcgggagc cccagtgacc cgaatcgtgg actggaatgg tgtgagagtg
7261 tcagctcctg aatcttctgc aactacattg agatctggtg gctttatgtc agtgccaata
7321 ccatatgcat ctaagcaaaa acaaattcaa tcatctggca ttagtaatcc aaattattct
7381 ccttcttcca tttctcgaac cactagttgg gttgaatcac aaaattcatc aagatttggg
7441 aatctatccc cataccatac agaggccctt aatacagtgt ggttgacccc acctggttca
7501 acagcatcct ccacactgtc ctctgtgcca cgtggttatt tcaatacaga tagattgcca
7561 ttgttcgcaa acaataggcg ataatgttgt aatatgaaat gtgggcatca tattcagtta
7621 attaggctta attaggtttg atttgatgtt aaaaaaaaa
//