Typing tool
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Typing tool
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Complete norovirus genomes
| MW661257 | GII.8 | |
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| GII.P8 |
ORF1: 4..5103
ORF2: 5084..6697
ORF3: 6697..7470
LOCUS MW661257 7558 bp RNA linear VRL 28-SEP-2021
DEFINITION Norovirus GII isolate BMH18-086 nonstructural polyprotein (ORF1),
VP1 (ORF2), and VP2 (ORF3) genes, complete cds.
ACCESSION MW661257
VERSION MW661257.1
DBLINK BioProject: PRJNA396739
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7558)
AUTHORS Nasheri,N., Flint,A., Reaume,S., Harlow,J., Hoover,E. and
Weedmark,K.
TITLE Genomic Analysis of Human Noroviruses Using Hybrid
Illumina-Nanopore Data
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7558)
AUTHORS Nasheri,N., Flint,A., Reaume,S., Harlow,J., Hoover,E. and
Weedmark,K.
TITLE Direct Submission
JOURNAL Submitted (23-FEB-2021) Bureau of Microbial Hazards, Health Canada,
251 SIR FREDERICK BANTING, Ottawa ON, Canada
COMMENT ##Assembly-Data-START##
Assembly Method :: Medaka v. v1.1.3; Pilon v. v1.23
Sequencing Technology :: Illumina; Nanopore
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7558
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="BMH18-086"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Canada: Ottawa"
/collection_date="2018-10-26"
/note="Viral RNA extracted from fecal samples;
genotype: GII.8_GII.P8"
gene 4..5103
/gene="ORF1"
CDS 4..5103
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QSD58390.1"
/translation="MKMASNDASAAAGNFNIANNSENTPPPVKEEASVLSNVKVGFKK
ILGAVPKQPKPPEVKTKDQPRVLVNGKALEVPPPPPNGEDVVYYNSKDDTVHGLPNLT
TVSCEGENLPYTVPPLSEREHRAAPEPLPGTILEMWDGEFYHYAIYVSGGKAIGVHKP
PAAISLATIELTPISLYWRPVYVPNYLVHPDTLKSLAGEKFPYTAFSNNCYNFCCWVL
DLKDSWLNRRSITRTTGFFKPYQPWNKKPLPTVDDGKIKKVANAVLCALGSLFSKPIK
DLIGKLKPLNFLNLLASCDWTFSGVVETVILAAELFGVFWTPPDVSNFIASLIGDFEL
QGPEDLAVELVPIIMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVM
KWFFPKKEEKAEMETLRAIEDAVLDMEAIGNNHLTALLKDRDSLLTYMKTLDLEEEKA
RKLSTKSSSPDIVGTINAILARIAAARSLLHRAKEEMYSRPRPVVVMISGRPGVGKTH
MARHLAKSVAGTMSGDQRVGLIPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALALQE
LADTCPVTLNCDRIENKGKMFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEA
PTIEKAKKDFPGQPDMWKEHFKADFSHLKLTLAPQGGFDKNGNTPHGKGTMKTLTQGS
LTARVAGLVHERKDEFQLQGGELQVYNFDTNKVSAFRKLAADNNYGFLETMRVGSSLK
DVKTVEDLKCALRSVSFKECEIIYKNVKYRISSDGCGKVSIEKLADNNSQTTREIITA
VTRLRQARARYYISCFQDLVYTLLQVAGASFVINRIVKKFNWERWVKAPETDEPTPSN
DKPDTEEEWEIAPKDVDSEGKKGKNKKGRGRKHTAFSSKGLSDEEYDEFKRLREEKQG
RYTIEEYLQDRDRYYEELAVARATEENFCEEEEIKIRQRIFRPTKKQRKEERGVLGLV
TGADIRKRRPDDFQPKGKLWADDSRSVDYNEKIEFEAPPSVWSRIVPLGTGWGFWVSS
NLLITTTHVLPKGIKELFGVDIKQVQVHKSGEFCRFRFPKPVRPDVSGLVLEEGAPEG
TVCSVLIKRSTGEMIPLAVRMGTHASMKIQGRAVGGQMGMLLTGANAKNMDLGTGPGD
CGCPYIYKRGNDIVVAGVHTAAARGGNTVICATQGPDGEAVLEGGEDHGTYCGAPILA
PGKAPKLSTKTKFWRSSPDSLPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEP
RGKPPRPSVLEEAKKTVMNVLEQTIEPAKPWTYSQACASLDKTTSSGSPHHVRKNEHW
NGESFTGPLADQASKANLMYEEGKHMDPMYTAALKDELVKTDKIYKKIKKRLLWGSDL
GTMVRCARAFGGLLDSMKESCISLPCRVGMNINEDGPLIFEKHSKYTYHYDADYSRWD
STQQRAVLSAAMEVMVKFSAEPELAQVVAEDLLAPSRLDVGDFVISVQEGLPSGVPCT
SQWNSIAHWILTLSAMSEVSGLSPEVVQANSCFSFYGDDEIVSTDINLDPEKLTRKLR
EYGLVPTRPDKTEGPLVITQDLNGLTFLRRTIVRDPAGWFGKLDRDSILRQLYWTRGP
NHENPFESMIPHSQRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQE
AMFRWMRFSDLSTWEGDRNLAPENVNEDGVE"
mat_peptide 4..1008
/gene="ORF1"
/product="p48"
mat_peptide 1009..2106
/gene="ORF1"
/product="NTPase"
mat_peptide 2107..2628
/gene="ORF1"
/product="p22"
mat_peptide 2629..3027
/gene="ORF1"
/product="VPg"
mat_peptide 3028..3570
/gene="ORF1"
/product="Pro"
mat_peptide 3571..5100
/gene="ORF1"
/product="RdRp"
gene 5084..6697
/gene="ORF2"
CDS 5084..6697
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QSD58391.1"
/translation="MKMASNDAAPSNDGAAGLVPEINHEVMAIEPVAGASLAAPVVGQ
LNIIDPWIRNNFVQAPAGEFTVSPRNAPGEFLLDLELGPELNPYLAHLARMYNGHAGG
MEVQIVLAGNAFTAGKILFAVIPPGFPYENLSPAQLTMCPHVVVDVRQLEPILLPMPD
IRNTFFHYNQSNGPKLRLVAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFEFNFLVPP
SVESKTKAFTLPILKISEMTNSRFPIPVDQMYTSRNENIVVQPQNGRVTLDGELQGTT
TLQPVSICGFRGTLQTRLADQPNYTYQVHLENLDGSPVDPTDEVPAPLGTPDFQAQLF
GVVSQRSSDNATRAHEARVNTNDPTFAPQIAQVRFKSPSHDFFDNEPIKFTPVGISVD
SENSYNQWLLPRYGGHLTNNTHLAPSVSPMFPGEQILFFRSFMPGASGHTDGAIDCLL
PQEWVAHFYQEAATAQTDVALIRFVNPDTGRVLFEGKLHKQGFITISNSGDHPIVMPA
NGYFRFEAWVNQFYSLAPVGTGSGRRRVQ"
gene 6697..7470
/gene="ORF3"
CDS 6697..7470
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QSD58392.1"
/translation="MAGAFFAGLAGDVVTPGIGSLINAGANAVNQKVEYDFNRQLQEA
SFKHDKEMLNAQINATTKLQRDMIAIKQGVLTAGGFSPTDAARGSINAPTTKILDWNG
SRYWAPGSMRTTAYSGNFISQGVKQPTPIVRSVKPQVQQSPAPSSVYSVGSVKSQSTQ
STQLTGSGTVSRAPTPSTTTTLSRTSEWVRSQNDRLSPFMGGALQTAFITPPSSKASS
SSGTVSTVPREILDSWTPAFNTRRQPLFAHMRRRGESRA"
ORIGIN
1 tgaatgaaga tggcgtctaa cgacgcttcc gctgccgctg gcaactttaa cattgccaac
61 aacagtgaaa acactccccc tcccgttaag gaagaggcga gtgtcctatc caacgtaaaa
121 gttggattca agaaaatatt gggggctgtg cctaagcagc ccaagccacc agaagtgaaa
181 accaaagatc aacccagggt gctggtcaat ggtaaggccc tggaggtgcc gcccccacca
241 ccaaatggtg aagacgtggt ttactataac agcaaggatg acactgtgca cggcctacca
301 aatctaacaa cagtcagctg tgaaggcgaa aaccttccgt acacagttcc tcctctcagc
361 gagagagagc acagggcagc accagaacca ttacctggca ccatactaga gatgtgggat
421 ggtgaattct accattatgc gatatatgtc tctggtggta aggccatagg ggtgcacaaa
481 cccccagctg caatcagcct tgccaccatc gagcttacac ctatatcgct ttactggagg
541 cctgtttatg tccccaatta cttggtccac cctgacacac tcaagagctt agctggtgaa
601 aaatttccat acaccgcatt tagcaataat tgttacaatt tctgttgctg ggttcttgac
661 ttgaaagact cgtggcttaa ccgcagatca ataactagaa caaccggttt cttcaagcct
721 tatcaaccct ggaacaagaa accacttccg acggtggatg atggaaaaat caagaaagtc
781 gccaatgcag tcctgtgtgc ccttggttca ctattctcaa aacctattaa ggacttgatc
841 gggaagctga aaccactgaa tttcttgaat ctcctcgctt cgtgcgactg gaccttctcc
901 ggagtggttg agaccgtcat actagctgct gaactattcg gtgtgttttg gacccccccc
961 gacgtgtcga acttcatcgc gtcactcatc ggggacttcg agttgcaggg tccagaggat
1021 ttagctgtgg agttggtgcc gattatcatg ggcggcatcg ggatggtgct gggattcacc
1081 gccgagaaga tcggccgaat gctatcatca gctgcatcga cccttagggc ctgtaaagac
1141 ctaggtaact acgcccttga catacttaaa ttggtcatga agtggttctt cccaaagaag
1201 gaggagaagg cagagatgga gaccttgagg gccatagagg atgctgtctt agacatggaa
1261 gcgattggaa ataatcacct cactgctctg ctgaaagaca gggacagcct cctaacctac
1321 atgaagactc tagacctcga agaggaaaag gcaagaaagt tatccacaaa atcatcttcc
1381 cctgacatcg tgggtaccat caatgccata ctagccagaa ttgccgcggc taggtctctc
1441 ctacacagag ccaaagaaga aatgtacagc agacctaggc ctgtcgtggt gatgatatca
1501 ggaagaccag gggttggtaa aacccatatg gctagacacc tcgccaagag tgtggcgggc
1561 accatgagcg gtgaccaaag ggtgggcctc atcccccgta atggagttga tcactgggat
1621 gcctacaggg gggaacgagt tgtcttgtgg gacgactatg gcatgggtaa cccagtgaag
1681 gacgcccttg ctctgcaaga actagcagac acttgtccag tcaccctcaa ttgtgacagg
1741 atagagaata agggaaagat gttcgatagc gaggtaataa ttataacaac caatctggcc
1801 aaccccgccc cgcttgatta tgtcaacttt gaggcatgtt cccgcagaat tgacttcctc
1861 gtctacgcag aggccccgac cattgagaag gcgaagaagg atttccccgg gcaaccagac
1921 atgtggaagg agcacttcaa agcagacttc tctcatctca aactcacact ggctccgcaa
1981 ggcggttttg acaagaacgg caacacgcca catgggaagg ggactatgaa gaccttaaca
2041 cagggttccc tcacagcaag agtggctggg cttgtgcacg aaaggaaaga cgagttccag
2101 ttacagggtg gggagttgca ggtctacaac tttgacacaa acaaggtatc ggctttcagg
2161 aagcttgctg cagacaacaa ctatggattt ctggagacaa tgagagtcgg ctcctcactc
2221 aaggacgtca agacagtgga agatcttaaa tgtgccctca ggagtgtcag tttcaaagaa
2281 tgtgagataa tctacaagaa tgtcaagtac cgcatatcat cagacggttg cggtaaggtc
2341 agcatagaga aactggcaga taacaactcc caaacaacca gagagattat cacggccgtc
2401 actagactac gacaggctcg tgctaggtac tacatcagct gtttccaaga cctagtctac
2461 acactcttgc aggttgccgg agcctcattt gtcattaata gaatagttaa gaagttcaac
2521 tgggaacgat gggtcaaggc tccggaaaca gatgaaccca caccaagtaa tgacaagccc
2581 gacactgaag aggaatggga gatcgccccc aaagatgtgg actctgaggg taaaaagggg
2641 aagaacaaga agggcagggg acgtaagcac actgcattct ccagcaaagg gcttagtgat
2701 gaggagtatg atgaattcaa aagactgagg gaagagaaac agggccgcta cacaatagag
2761 gagtacctcc aggacagaga ccggtactat gaagagctgg cagtggcccg ggccactgaa
2821 gagaacttct gtgaagagga agagataaag atcaggcaaa gaatattccg ccccaccaaa
2881 aagcagagga aggaggagcg gggggttctg ggactcgtca caggagcaga catcaggaaa
2941 cggagacccg atgatttcca accaaaagga aaactgtggg cagatgattc taggagcgtc
3001 gactacaatg agaagatcga gtttgaagct cctcctagcg tctggtcaag aatcgtcccg
3061 cttgggactg gttggggatt ctgggtctca tccaacttac taatcaccac cacacatgtg
3121 ctgcccaaag gcatcaaaga gctttttggg gtggacatca aacaagtcca agttcacaaa
3181 tcaggtgaat tttgcagatt caggttccca aaaccagtga ggccagatgt ctctgggttg
3241 gtactagaag aaggggcccc cgaaggcaca gtgtgctctg ttctcatcaa gaggtcaaca
3301 ggagagatga tcccccttgc agttaggatg ggcacccacg cctctatgaa gatccagggg
3361 cgcgctgttg gcggccagat gggcatgctg ctcactggag ccaacgctaa gaacatggat
3421 ttgggtaccg gccccgggga ttgtggttgc ccgtacatat acaagagggg caatgacatc
3481 gtggtggccg gcgtccacac agcagcagcg cgtgggggca acacggtcat ctgtgcaacc
3541 caaggacctg atggtgaggc agtgttggaa gggggagagg accacggtac ttactgtgga
3601 gccccaatat tagcccctgg taaagcgccg aagcttagca caaagactaa gttttggcgc
3661 tcatcccctg attcccttcc ccctgggacg tatgaaccag cttaccttgg gggtaaggat
3721 ccccgtgtgg agaaagggcc atcactccaa caagtgatgc gagaccaact caaacccttc
3781 acagaaccca ggggcaagcc acctaggccg tcagtgctgg aggaagccaa gaagacagtc
3841 atgaatgtac tggagcagac catagaacca gctaagccat ggacctactc tcaagcctgt
3901 gcttcattgg ataaaacaac atccagtggc agtcctcacc acgtcaggaa gaatgaacac
3961 tggaacgggg agtctttcac tgggcctctt gcagatcaag cctcaaaagc caacctgatg
4021 tatgaggagg gtaaacacat ggaccctatg tacacagcag ccctcaagga cgagctggtg
4081 aaaactgaca aaatctataa gaaaatcaag aagaggttgt tgtgggggtc tgatctgggg
4141 acaatggtga ggtgtgctcg agcgtttgga ggattgctcg acagcatgaa agagagctgc
4201 atctccttac cctgtagggt tggcatgaac ataaatgaag atggaccact catatttgaa
4261 aaacattcca aatacaccta tcactatgat gctgattact ctaggtggga ctcaacacag
4321 cagagggctg tcctgagtgc agccatggag gtaatggtga aattctctgc tgagccggaa
4381 ctggctcagg tggttgccga agacctcctt gcacccagcc gtcttgacgt gggtgacttc
4441 gtcatctccg ttcaagaggg tcttccatcg ggtgtcccct gcacgtcaca gtggaactca
4501 atcgctcact ggatcctgac tcttagtgct atgtctgagg tctctggtct ttcccctgag
4561 gttgtgcaag ccaactcctg tttctcattc tatggggatg atgagatagt cagcacagat
4621 ataaacctag acccagaaaa actcaccagg aaactgaggg agtatggcct cgtcccaaca
4681 aggccagaca aaactgaggg cccacttgtg atcactcagg atttgaatgg tctcacattc
4741 ttgaggcgaa ccatagtgcg ggaccccgca ggttggtttg gaaaattgga ccgtgattcc
4801 attctaaggc agttatactg gaccagagga cccaatcatg agaacccctt tgaaagcatg
4861 attccccact cccagagagc aacccagtta atggcccttc ttggggaagc ctcgttgcat
4921 ggtccccagt tttacaagaa ggtgagtaaa atggtcatca atgagatcaa gagtggtggt
4981 ctggagtttt acgtgcccag acaggaggcc atgtttagat ggatgagatt ttcagacctc
5041 agcacgtggg agggcgatcg caatctggct cccgagaatg tgaatgaaga tggcgtcgaa
5101 tgacgcagct ccatcgaatg atggcgcggc tggcctcgta ccagagatca accatgaggt
5161 catggccata gagcctgttg caggggcctc tttagcagcc cctgtcgtag gacaacttaa
5221 tataattgat ccctggatta gaaataattt tgtacaagcc cctgctggag aattcactgt
5281 ttcgcctaga aatgctccag gtgaattttt gttagatcta gagttaggtc cagaactgaa
5341 tccttatctt gctcaccttg cacgcatgta taatgggcat gcaggtggta tggaggtgca
5401 gatagtgctt gctgggaatg cgttcacagc gggcaaaata ctgtttgcag tcataccacc
5461 tggattcccc tatgaaaatt tgtcacctgc acaattgacc atgtgcccgc atgtagtggt
5521 ggatgtgaga cagcttgaac caatcctgct gcccatgcca gacatccgta atacattctt
5581 ccattacaat cagagcaatg ggccaaaact cagattagta gccatgcttt acacacccct
5641 aagggctaac aatgctggtg atgatgtctt cacagtctcc tgcagggttt tgactcgtcc
5701 gtcaccagat tttgaattca attttcttgt ccccccatct gttgaatcta agactaaagc
5761 tttcactctt ccaattctta agatatctga gatgacaaat tcaagatttc ccataccagt
5821 tgaccagatg tatactagta ggaatgaaaa tatagttgtt caaccacaga atggcagggt
5881 gacacttgat ggagagttac agggcacaac cacacttcaa ccggtgtcca tttgtggctt
5941 ccgagggacg ctgcagacca ggctggcaga tcaaccaaat tacacatacc aagtgcacct
6001 tgagaatttg gacggctcac ccgtcgatcc gacagatgaa gtcccagccc ccctggggac
6061 gccagatttt caggcccagc tatttggagt tgtcagtcaa aggagtagtg ataatgccac
6121 cagggcacat gaggctaggg tcaacaccaa cgatcctacc ttcgcgcccc agatcgccca
6181 ggtgcgtttc aaatcaccat cccacgactt ctttgacaat gaacccatca agttcacacc
6241 agttggaatt agtgttgata gcgaaaacag ctacaaccaa tggctccttc ccaggtatgg
6301 cgggcacttg acaaacaaca cccacctggc cccctctgtg tccccaatgt tccccggcga
6361 gcagattctc ttcttccgct cgttcatgcc aggtgccagt ggtcatactg atggtgctat
6421 tgactgcctc ttaccacaag agtgggttgc ccacttctat caggaggccg caactgcgca
6481 aacagatgtg gctctgatta gatttgtgaa ccccgacaca ggcagagtgc tatttgaagg
6541 gaagctacac aagcagggct ttataaccat ctccaacagt ggggaccacc ccattgttat
6601 gcctgctaat ggatacttca ggtttgaggc atgggtcaac caattttact ctctcgcccc
6661 cgtgggaact ggaagtgggc gcagaagggt tcaataatgg ctggagcttt ctttgcgggt
6721 ctggctggtg atgtggtgac ccctggcatc gggtcgctca tcaatgcagg tgctaatgca
6781 gtgaaccaaa aggttgaata tgacttcaat aggcaacttc aagaagcttc ttttaaacat
6841 gacaaggaga tgttgaatgc tcaaattaat gccacaacca aattgcagag ggacatgatt
6901 gccatcaagc agggggtttt gaccgctggc ggcttttccc ccactgatgc tgcaagaggt
6961 tccatcaatg ctccaaccac caaaattctt gactggaatg gatctaggta ctgggcgcca
7021 ggatcaatga gaacaacagc atactctggc aatttcatat cacagggagt taagcaacct
7081 acacccattg ttagatctgt gaaacctcaa gtacagcaat ctcctgcccc ttcttctgtt
7141 tattctgtag gttctgttaa gtcacaatca acacaatcaa ctcaattaac agggtcaggg
7201 actgtatcaa gggcacccac cccctcaaca accacaacac tgtccagaac aagtgagtgg
7261 gtgaggagcc agaatgatag gctgagcccc tttatgggag gcgcactcca gacagctttc
7321 atcacgcccc catcgagtaa ggcttcatcc tcatcaggaa cagtctcaac cgttcctaga
7381 gaaattttgg actcctggac tcctgcattt aacacgcgca ggcagccgct cttcgcccac
7441 atgcgtaggc gaggggagtc acgggcttag tgaaaagaat gatttggtta gattatatct
7501 ttttcttacc tattctatct tttaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//