Typing tool
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Typing tool
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Complete norovirus genomes
| MW305698 | GII.14 | |
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| GII.P7 |
ORF1: 1..5063
ORF2: 5044..6654
ORF3: 6654..7448
LOCUS MW305698 7494 bp RNA linear VRL 18-JUL-2024
DEFINITION Norovirus GII isolate CMH-047-07 nonstructural polyprotein (ORF1)
gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete
cds.
ACCESSION MW305698
VERSION MW305698.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7494)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A.U.A., Ford-Siltz,L.A., Green,K.Y.,
Galeano,M.E., Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N.,
Ushijima,H. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses provide insights on
evolutionary dynamics and evidence of coexisting viral populations
evolving under recombination constraints
JOURNAL PLoS Pathog 17 (7), e1009744 (2021)
PUBMED 34255807
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 7494)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7494
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="CMH-047-07"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Thailand"
/collection_date="14-Mar-2007"
/note="genotype: GII.14[GII.P7]"
gene <1..5063
/gene="ORF1"
CDS <1..5063
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QPJ59430.1"
/translation="FGSQNSVNDSINATPSNKEEVGAFSNIKVGFKKMLGAVPKGTRA
PSSGQHCPTVKIGPKTLTIPPEPPNGEDTVQFDAKSETIIGLPDLTTVQNEHENTPYT
VPPLSEREHRSATEPLPGTILEMWDGEFYHYSVYVSDGKALGVHKPPAAISLATIELT
PISLYWRPVYTPNYLVSPDTLKGLAGEKFPYTAFSNNCYNFCCWVLELNDTWLNRRCI
SRTTGFFKPYQSWNRKPLPTVDDGKIKKVANAILCALGSLFSKPIKDLLGKLKPLNLL
HLLASCDWTFAGIVETVILMAELFNIFWTPPDVSNFIASLIGDFELQGPEDLAVELVP
VVMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMKWFFPKKEEKAE
METLRAIEDAVLDMEAIGNNHLTTLLKDKDSLTAFMKTLDLEEEKARKLSTKSSSPDI
VGTINAILARIAAARSLLHKAKEEMFSRIRPVVVMISGRPGIGKTHMARHLAKSIANT
MSGDQRVGLVPRNGVDHWDAYRGERVVLWDDYGMGSPVKDALTLQELADTCPVTLNCD
RIENKGKMFDSDVIIITTNLVNPAPLDYVNFEACSRRVDFLVYAESPEIEKVKRDFPG
QPDMWKDHFKPDFSHIKLTLAPQGGFDKNGNTPHGKGTMRSLTQGSLTARVAGLVHER
KDEFQLQGSDLQTYNFDTNRVSAFRKLAADNKYGIMETMRVGAALKNVKTLEDLKLAL
RDVKFNECEIIYKNSKYRVSSNGKGSVSVDKIENNASQTANEVQSALLRLRQARARYY
ISCFQDLVYTLIQVAGASFVVNRISKRFCWERWVKPTETQEVNESEKEVAQGRWEIEP
KDTEPEGKKGKNKKGRGKKHTAFSSKGLSDEEYDEFKRIREERNGKYSIEEYLQDRDR
YYEEVAVARATEEDFCEEEEAKIRQRIFRPTKKQRKEERGVLGLVTGTDIRKRRPDDF
QPKGNLWADDTRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSNLLITTTHVLPKG
VKELFGVEIKQIQVHKSGEFCRFRFPRPIRPDVTGLVLEEGAPEGTVCSILIKRPTGE
MIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDCGCPYIYKRGNDI
VVAGVHTAAARGGNTVICATQGQDGEAVLEGNEDLGTYCGAPILGPGKAPKLSTKTKF
WRSSPDALPPGTYEPAYLGGKDPRVERGPSLQQVMRDQLRPFTEPRGKPPRPAVLEEA
KKTVMNVLEQTIDPAKPWSYSQACASLDKTTSSGSPHHVKKNDHWNGESFTGPLADQA
SKANLMYEQAKHVQPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGTMIRCARAFGGL
MDSMKASCIALPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDSTQQRSILSAAME
VMVRFSAEPELAQVVAEDLLAPSQLDVGDFIISVQEGLPSGVPCTSQWNSIAHWILTL
SAMAEVSGLSPDVVQAHSCFSFYGDDEIVSTDINLDPMKLTQKLREYGLVPTRPDKTE
GPLVITEDLTGLTFLRRSIARDPAGWFGKLDQDSILRQLYWTRGPNHENPYESMVPHS
QRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEAMFRWMRFSDLST
WEGDRNLAPEGVNEDGVE"
mat_peptide <1..971
/gene="ORF1"
/product="p48"
mat_peptide 972..2069
/gene="ORF1"
/product="NTPase"
mat_peptide 2070..2588
/gene="ORF1"
/product="p22"
mat_peptide 2589..2987
/gene="ORF1"
/product="VPg"
mat_peptide 2988..3530
/gene="ORF1"
/product="Pro"
mat_peptide 3531..5060
/gene="ORF1"
/product="RdRp"
gene 5044..6654
/gene="ORF2"
CDS 5044..6654
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ59431.1"
/translation="MKMASSDATPSDDGAAGLVPEINSEVMALEPVAGASIAAPVVGQ
QNIIDPWIRNNFVQAPAGEFTVSPRNSPGELLLDLELGPELNPYLAHLARMYNGHAGG
MEVQIVLAGNAFTAGKILFAAIPPSFPYENLSPAQLTMCPHVIVDVRQLEPVLLPMPD
IRNVFYHYNQNNSPKLRLVAMLYTPLRANNSGDDVFTVSCRVLTRPSPDFQFTFLVPP
TVESKTKNFTLPVLRVSEMTNSRFPVVLDQMYTSRNENIIVQPQNGRCTTDGELLGTT
ILQSVSICNFKGTMQAKLNEEPRYQLQLTNLDGSPIDPTDDMPAPLGTPDFQAMLYGV
ASQRSSRDNATRAHDAQIDTAGDTFAPKIGQVRFKSSSNDFDLHDPTKFTPIGVNVDD
QHPFRQWSLPNYGGHLALNNHLAPAVTPLFPGEQILFFRSYIPSAGGHTDGAMDCLLP
QEWVEHFYQEAAPSQSDIALVRFINPDTGRVLFEAKLHKQGFLTIAASGDHPIVMPTN
GYFRFEAWVNPFYTLAPVGTGSGRRRIQ"
gene 6654..7448
/gene="ORF3"
CDS 6654..7448
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ59432.1"
/translation="MAGAFLAGLAGDVVASSLGSLVGAGANAINQKVEYDFNRQLQEA
SFRHDKDMLKAQVAATAGLQQAMIDIKREALTAGGFSPADAARGAVRAPMTQILDWNG
SRYWAPNSMKTTGYSGTFASQGIKSSPHLSNQTPSAVKSTKPLPSISSSSSVYSSPST
APSQSTQSTTLSAGTGSSRSNTVSTKTSTLSRTSDWVRGQNEMLGPFMSGALQTAYVT
PPSSRASSQGTVSTVPKAVLDSWTPMFNTHRQPLFAHLRRRGESQI"
ORIGIN
1 cctttggcag tcaaaactct gtcaatgaca gtatcaacgc caccccttcc aataaggaag
61 aggttggtgc attctccaac atcaaagttg gatttaagaa aatgctgggt gctgtaccca
121 agggcaccag agcacccagc agtggtcaac attgccccac agttaagatc gggcctaaaa
181 cattaacaat tccccctgag cccccaaatg gtgaagacac tgtgcagttt gatgcaaagt
241 cggaaactat aatcgggctg ccggacttga caacggtgca aaacgagcat gaaaacaccc
301 catacaccgt ccccccatta agtgagaggg agcacagatc ggccactgaa ccacttcctg
361 gcacaatatt ggagatgtgg gatggtgaat tttaccacta ctccgtgtat gtcagcgatg
421 gcaaagctct gggggtccac aaaccaccgg ctgctataag cctcgcgacg atagagctca
481 cccctatatc tctctattgg agacccgttt acacccccaa ctatttggtc tccccagaca
541 cattgaaagg cctcgctggt gagaagttcc cctacacggc cttcagtaac aattgttata
601 acttttgttg ttgggtgctt gagctcaacg acacgtggct caacagaaga tgcatttcca
661 gaaccaccgg cttcttcaaa ccttatcaat cttggaacag gaagcccctc ccaaccgttg
721 atgatggaaa gatcaaaaag gtggccaacg cgatcctctg cgcacttggc tcactgttct
781 caaaaccaat caaagatttg ttaggcaaac ttaagccatt gaacctgctg cacttgcttg
841 cgtcatgcga ttggacgttt gcaggtatag tggagacagt catcttaatg gcagaacttt
901 tcaatatctt ctggaccccg ccagatgtct ctaattttat agcctccctg ataggtgatt
961 ttgaattaca agggcctgag gacctggctg tggaactcgt tcctgtggtt atgggtggca
1021 taggaatggt tctcggcttc accgctgaga agataggccg tatgctgtca tccgccgcat
1081 caacactgcg ggcatgcaaa gacctaggga attatgccct tgacattctc aaattggtca
1141 tgaagtggtt cttcccaaag aaggaagaga aagctgagat ggaaaccttg agggcgatcg
1201 aggatgctgt cctagatatg gaagccatag ggaataacca tctcacgacc ctcctcaagg
1261 acaaagacag cctcacggct tttatgaaga ccctggacct agaagaggaa aaagcaagaa
1321 aactgtccac taagtcatct tcaccggaca tcgtcggcac cattaatgcc atactagcta
1381 ggattgctgc tgccagatcc cttctacata aggccaaaga agagatgttt agtaggatca
1441 gaccagtggt cgttatgata tcaggcagac ctggcattgg caaaacccac atggcaagac
1501 atttggctaa gagcatcgcc aacaccatga gtggcgacca gagagtcggg ctcgtcccac
1561 gtaacggtgt cgaccactgg gatgcctaca gaggagagag ggtggtcttg tgggatgact
1621 acggtatggg gagccctgtt aaagatgcct taacactaca ggagctggcc gacacctgtc
1681 cagtcacttt aaattgtgat aggattgaga acaaggggaa gatgttcgac agtgatgtca
1741 tcataatcac aaccaacctg gtcaaccccg cgcccctcga ctatgtgaac ttcgaggcgt
1801 gttccaggag agttgacttc ttggtctatg cagagtcacc agagattgaa aaggtcaaga
1861 gggacttccc tggccaacct gatatgtgga aagaccattt taagccagac ttttctcaca
1921 tcaagctaac tttagccccc cagggcgggt ttgacaagaa tggtaacact ccacacggta
1981 agggtaccat gcggtccctg acccaggggt ccctgactgc aagagttgca ggccttgtcc
2041 atgagaggaa agatgagttc caactccaag gaagcgacct ccaaacatac aattttgaca
2101 ccaacagagt ctccgcattt agaaaactgg ctgcagataa caagtatggt atcatggaaa
2161 cgatgagagt aggtgcggca ctcaaaaatg taaagacctt ggaagatcta aagcttgcat
2221 taagggatgt aaaattcaat gagtgtgaaa taatttacaa gaactctaag tatcgagtct
2281 cttccaatgg taaaggctca gtttctgttg acaaaattga gaacaatgca tcccagaccg
2341 cgaacgaggt acaatcagca cttctcaggc tcagacaagc gagggccaga tattacatca
2401 gctgcttcca agacctcgtc tacactctca tacaggttgc cggagcatca ttcgttgtca
2461 acagaatttc caaaaggttc tgctgggaaa ggtgggtcaa accaaccgag acccaggaag
2521 tgaatgagtc cgaaaaggaa gtggctcaag gtaggtggga aattgagccc aaggacacag
2581 aaccagaagg caagaagggt aaaaacaaga aaggaagggg caagaaacac acagctttct
2641 ctagcaaagg cctgagtgat gaagagtatg acgagttcaa gagaatcagg gaagaaagga
2701 atggaaagta ctccattgag gaatacctgc aagaccggga ccgctattat gaagaagtgg
2761 cagttgcccg ggcaacagag gaggacttct gtgaagagga agaggccaaa ataagacaaa
2821 gaattttccg cccgacaaag aaacaaagga aggaggaaag gggtgtactt ggcttagtca
2881 ccggcacaga catcagaaag aggagaccag acgattttca accaaaaggc aatctatggg
2941 cagatgacac caggagtgtg gactacaatg agagacttga ttttgaagcg cccccaagtg
3001 tctggtcaag aatagtccca ttaggcactg gttggggttt ctgggtttca tccaaccttc
3061 taatcacaac aacacacgtc ctgcctaaag gggttaagga actctttgga gttgaaatca
3121 aacagatcca agttcacaag tctggagagt tttgcaggtt cagattccca agaccaatca
3181 ggccagatgt cacagggctc gtgttggagg aaggcgcccc agaaggcact gtctgttcca
3241 tactcataaa aagacctaca ggtgagatga tccccttggc agtgaggatg ggcacacacg
3301 catccatgaa aatacaaggc aggaccgttg gtggccagat gggaatgctt ctaacaggtg
3361 caaatgcgaa gaacatggat cttggcaccg gccctggtga ctgcggttgt ccctacatct
3421 acaaacgcgg caacgacata gttgtcgcgg gtgtccacac cgcagcagcc cggggaggta
3481 acactgtcat atgcgccact caagggcaag atggggaagc agtccttgag ggaaatgagg
3541 acctcggtac ctactgtggc gccccaattc tgggccctgg taaggcacct aaactcagca
3601 cgaagaccaa gttttggcgc tcatcaccag atgccttgcc gcctggcaca tatgaacctg
3661 cttacctggg aggcaaagac cccagagtgg aaagaggacc ttccctgcag caagtcatga
3721 gagaccagtt gagacccttc acagaaccca ggggaaaacc gcctagacct gcagtcttag
3781 aagaagccaa gaagacagtg atgaatgttt tagaacaaac cattgaccct gcaaaaccgt
3841 ggtcctactc gcaagcatgt gcctcactgg ataaaaccac ttctagtggt agcccccatc
3901 atgtaaagaa aaatgaccac tggaatgggg agtccttcac tggtcccctt gcagatcagg
3961 catccaaagc caacctcatg tatgaacagg ctaaacatgt gcagcccgtg tacacggccg
4021 cgctcaaaga tgagcttgtt aagactgaca agatctacaa aaagataaag aagaggctcc
4081 tatggggatc ggaccttgga acaatgatca ggtgcgccag ggcttttggt ggtctcatgg
4141 acagcatgaa ggcaagctgt atagctcttc catgcagggt aggaatgaac atgaatgaag
4201 atggccctat catatttgac aaacattcta agtataggta ccactatgat gctgactatt
4261 ctaggtggga ctcaacccag caaaggagca ttctttctgc cgctatggaa gtgatggtgc
4321 gattttctgc tgaaccagaa ttggcacaag tggttgcaga ggaccttttg gcgcctagtc
4381 agcttgatgt tggtgatttt atcatctcag ttcaggaggg cctgccatca ggagtcccat
4441 gtacatcaca atggaactca atagcacact ggatcctaac tttgagtgca atggcagaag
4501 tgtcaggtct ctcaccagat gttgtccaag ctcactcttg cttttcattt tatggggacg
4561 atgagatcgt cagcactgac atcaaccttg accccatgaa gttgacacag aaactcaggg
4621 agtacggcct ggtccccacc cgacctgata aaactgaagg tcccctcgtc ataactgaag
4681 acctcaccgg cctgacattc cttcgtaggt cgattgcacg ggacccagct ggatggtttg
4741 gaaaattgga ccaagattca atcctcaggc aactatactg gacaaggggg cctaaccatg
4801 agaacccgta cgagagcatg gtccctcatt cccagcgagc cacacagctt atggctcttc
4861 tcggtgaggc ttcactgcat ggtccccaat tttacaagaa agtcagcaag atggttatta
4921 atgagattaa gagtggtggt ctggaatttt atgtgcccag acaggaggcc atgttcaggt
4981 ggatgagatt ctctgacctc agcacatggg agggcgatcg caatcttgct cccgaaggtg
5041 tgaatgaaga tggcgtcgag tgacgctact ccatctgatg atggtgcagc cggcctcgta
5101 ccagagatca acagtgaggt tatggctctt gaacccgtcg ctggggcctc cattgcagcc
5161 cccgtagtcg gccaacagaa tataattgat ccctggatta gaaataattt tgtacaagcc
5221 cctgctggtg aatttacagt ttcccctaga aactctcctg gagaacttct acttgatttg
5281 gaattgggtc ctgaacttaa tccctatctt gcacatttgg ccaggatgta caatgggcat
5341 gcaggaggaa tggaagtgca gatagtactg gctgggaatg cgttcacagc tggtaaaatc
5401 ctatttgctg ccatcccgcc tagcttcccc tatgaaaatt tgtcacccgc tcaattgact
5461 atgtgccccc atgtgatagt ggatgtgaga caattagaac cagtgcttct gccaatgcca
5521 gatataagaa atgttttcta ccactataac cagaacaata gtcccaaact taggcttgta
5581 gctatgcttt atactcctct gagggctaac aactcaggtg atgacgtgtt cacggtgtct
5641 tgccgcgttt taacacgtcc ttctccagat ttccagttca cctttctggt cccacctaca
5701 gttgagtcta aaactaagaa tttcaccctt cccgttctta gagtctcaga gatgacaaat
5761 tcaaggttcc ccgttgtttt ggaccaaatg tatacaagca ggaatgaaaa catcattgtc
5821 caaccccaaa acggcaggtg cacgactgac ggtgagctgc ttggcactac catcttgcag
5881 tctgtgtcta tttgcaattt taaaggaaca atgcaggcaa agctgaatga agaaccacga
5941 taccagttac aactcaccaa cttggatggg tcacccatag atccaacaga tgatatgcct
6001 gcccctcttg gcacaccaga tttccaggcc atgttatatg gcgttgcaag ccaacgctct
6061 tccagagaca atgccaccag ggcacatgat gcacagattg acactgcggg tgacacattc
6121 gccccaaaaa ttggccaggt tcgttttaaa tcaagctcta atgattttga cctacatgac
6181 cctacaaaat tcacacctat tggtgtcaat gtggatgatc agcacccttt tagacagtgg
6241 tccctaccaa actacggtgg tcaccttgcc ctgaacaatc atttagcccc cgctgtgaca
6301 ccactctttc ctggcgagca gattttgttc ttcaggtcat acattccaag cgccggaggc
6361 cacacagacg gtgctatgga ctgcttgctg ccccaagagt gggtagagca cttctaccag
6421 gaagctgccc cttcccaatc tgatatcgca ctggtaaggt tcatcaaccc tgacacagga
6481 agagtgctct ttgaagctaa attgcataaa caaggtttcc tcacaattgc agcatctgga
6541 gatcacccta ttgtgatgcc cactaatggt tactttaggt ttgaagcttg ggtcaaccct
6601 ttctatactc tcgcccccgt gggaactggg tctgggcgca ggaggattca ataatggctg
6661 gagctttcct tgcaggcttg gcaggtgacg ttgtggcttc cagcttgggc tcacttgtgg
6721 gcgctggagc caacgccatc aaccagaaag tggagtatga cttcaacaga cagctccaag
6781 aggcatcttt tagacatgat aaggatatgc tcaaagccca ggttgcagca acagcaggcc
6841 ttcaacaggc catgatagac atcaagcggg aggcattgac cgcaggcggc ttttcccccg
6901 ctgatgctgc aagaggtgca gttagagcgc ctatgacaca gattcttgac tggaatggtt
6961 ctaggtattg ggcccccaac tccatgaaga caactggcta ttcaggtaca tttgcttccc
7021 aaggcattaa aagttccccc cacctgtcta atcaaactcc aagtgctgtt aaatctacca
7081 aacctttacc atctatatct agttcttcta gtgtatatag ttctccttct actgcccctt
7141 cacaatcaac acaatcaaca acgctgtctg caggaacagg gtcctccaga tctaacaccg
7201 tgtccacaaa gacctctaca ctgtcgagga caagtgactg ggtcagaggt caaaatgaga
7261 tgcttggccc gttcatgagt ggtgcactcc aaactgctta tgtcacacca ccatcgagca
7321 gggcctcatc acaagggacg gtctcgaccg tacccaaggc tgttttggac tcctggactc
7381 ccatgttcaa cacccacagg cagcctctct tcgcccactt gcgtaggcga ggggagtcac
7441 agatttagtg aaaaggatga ttagggtttc ttcctttccc cttcttattc tttt
//