Typing tool
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Typing tool
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Complete norovirus genomes
| MW305678 | GII.13 | |
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| GII.P16 |
ORF1: 1..5066
ORF2: 5047..6675
ORF3: 6675..7406
LOCUS MW305678 7423 bp RNA linear VRL 06-JUL-2021
DEFINITION Norovirus GII isolate 11470 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MW305678
VERSION MW305678.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7423)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses reveal coexistence of
viral populations evolving under recombination constraints
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7423)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7423
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="11470"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Japan"
/collection_date="25-Feb-2013"
/note="genotype: GII.13[GII.P16]"
gene <1..5066
/gene="ORF1"
CDS <1..5066
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QPJ59370.1"
/translation="VACNNNNDKEKSSGEGLFTNMSSTLKKALGARPKQPAPRDNSQK
PPRPPTPELVKRIPPPPPNGEEEEPVIRYGVKSGISGLPELTTVPQPDVANTAFSVPP
LSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAISMAKVELTPLS
LYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLNDSWLNRRMVQRT
TGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLIGKIKPLNILNIL
ATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAVELVPVVM
GGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKEEANELAM
VRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLSTKSASPDIVGT
INALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLAREVARKVASTLTG
DQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELADTCPLTLNCDRIE
NKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAKRDFPGQPD
MWKDAFKSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGLLHERMDE
FELQGPTVTTFNFDRNRIAAFRQLAAENKYGLVDTMRVGNQLKGVKTMEALKQAIKNV
IIKRCRIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHHLKHARIRYYVKC
VQEAVYSIIQIAGAAFVTTRIVRRMNIQELWSKPPLDQNESEAKEEALKSEDDEFIIS
SKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRD
RYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVTGSEIRKRNPDD
FKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPSLFITSTHVIPA
GITEAFGVPIKQIQVHKSGEFCRFRFPKPIRSDVTGMILEEGAPEGTVATVLIKRPTG
ELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDCGCPYIYKRGND
YIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGPGGAPKLSTKTK
FWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTESRGKPPRPSVLEA
AKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNEFWNGETFTGKLADQ
ASKANLMFEEGKHMTPVYTAALKDELVKTDKVYGKIKKRLLWGSDLSTMIRCARSFGG
LMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDSTQQRAVLAAAL
EIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKISINEGLPSGVPCTSQWNSIAHWLLT
LCALSEVTKLSPDIVQANSMFSFYGDDEIVSTDIKLDPEKLTTKLKEYGLKPTRPDKT
EGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPNHEDPNETMIPH
SQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQEPMFRWMRFSDLS
TWEGDRNLAPNFVNEDGVE"
mat_peptide <1..962
/gene="ORF1"
/product="p48"
mat_peptide 963..2060
/gene="ORF1"
/product="NTPase"
mat_peptide 2061..2591
/gene="ORF1"
/product="p22"
mat_peptide 2592..2990
/gene="ORF1"
/product="VPg"
mat_peptide 2991..3533
/gene="ORF1"
/product="Pro"
mat_peptide 3534..5063
/gene="ORF1"
/product="RdRp"
gene 5047..6675
/gene="ORF2"
CDS 5047..6675
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ59371.1"
/translation="MKMASNDAAPSNDGAASLVPEAINETMPLEPVAGASIAAPVAGQ
TNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAIPPNFPVDMISPAQITMLPHLIVDVRTLEPIMIPLPD
VRNVFYHFNNQPQPRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFIYLVPP
SVESKTKPFTLPILTISELTNSRFPIPIEQLYTAPNENNVVQCQNGRCTLDGELQGTT
QLLSSAVCSYRGRTVANSGDNWDQNLLQLTYPSGASYDPTDEVPAPLGTQDFSGILYG
VLTQDNVSEGTGEAKNAKGVYISTTSGKFTPKIGSIGLHSITENVHPNQQSRFTPVGV
AQNENTPFQQWVLPHYAGALALNTNLAPAVAPTFPGEQLLFFRSRVPCVQGLRGQDAF
IDCLLPQEWVNHFYQEAAPSQADVALIRYVNPDTGRTLFEAKLHRSGFITVSHTGAYP
LVVPPNGHFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6675..7406
/gene="ORF3"
CDS 6675..7406
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ59372.1"
/translation="MAGAFIAGLAGDMLTSAVGSLTSAGANAINQKLNFDYNKQLQNA
SFQHDKEMLQAQIDATKKLQSEMIAIKHGVLTAGGFSPADAARGAVNAPMTRVLDWSG
TRYYAPNSVQTTSYSGQFTPSPVHRAQVKSPSNSSQRTAAPSSIRSLSTQSTSLGSTS
SGGSSTASSSSRTADWVQQQRALSPYMQGALQTAYVTPPSSRASSMSSVSTVPKGVLD
SWTPVFNTRRQPLFAHLRKRGESQA"
ORIGIN
1 ccgttgcttg caacaacaac aacgacaagg aaaaatcttc aggtgaaggc ttattcacaa
61 atatgtcttc caccttaaag aaagccctcg gggcccggcc caaacagcct gccccgaggg
121 acaactcaca aaagccccca agaccaccaa ctcccgagtt ggttaagagg ataccccctc
181 ccccacctaa tggtgaagaa gaagaaccag tcattaggta tggggttaag agtggaatct
241 ctggcctgcc cgagctcaca acagtccctc aaccggatgt ggccaacacg gcattcagtg
301 tcccaccgct gagcttgaga gaaaacaggg aggccaagga accgctgaca ggggcaatat
361 tagagatgtg ggatggagag atataccact atggcctgta cgtggagaaa ggcttagtgt
421 tgggtgtgca taaaccacct gcagctataa gcatggcaaa agtggagctg acgccgttgt
481 cattgtactg gcgtgtggtc tacacccccc aatacctcat ctcccctgaa actctcagga
541 ggctcaacgg agaggcattc ccttacactg cctttgacaa caactgctat gccttttgct
601 gctgggtatt agacctcaat gactcatggc ttaacaggag gatggtgcaa agaacaacag
661 gctttttcag accttaccaa gagtggaaca gaaaacccct gcccactatg gatgactcca
721 aaatcaagaa ggtggcaaac atattcctgt gttcattgtc cacgttgttc accagaccta
781 taaaagacct cataggaaaa attaaaccat taaacatctt gaacatcctg gcaacgtgtg
841 actggacatt cgccggaata gtggagtctc tgatattact tgctgaactc tttggagttt
901 tctggacacc cccagatgtg tctgctatga tcgctccttt acttggagac tacgagttgc
961 aagggccaga agaccttgcc gttgagctcg tacctgtagt aatgggaggg attggtttgg
1021 tgttgggatt caccaaagag aaaattggca aaatgttgtc ctcagcagca tcaacgctca
1081 gggcttgtaa agatcttggt gcctatggct tagagatact caaattggtc atgaagtggt
1141 tcttcccaaa gaaagaagag gccaatgagc tagccatggt gagagctata gaggatgctg
1201 tactggatct tgaggcaata gaaaataatc acatgacaac tctgttgaaa gacaaagaca
1261 gcctagcaac ctacatgaaa acactagaca tggaggagga aaaagccaga agattgtcca
1321 caaaatctgc atcccctgac atagttggga cgatcaacgc cctgctggct cgaatagcag
1381 cggctaggtc actagtccac agggccaagg aggagttatc tagcaggata agaccagtgg
1441 ttgttatgat atctggcaaa ccagggatag gcaaaactca tttggccagg gaggtggcaa
1501 gaaaggtggc atccactctc acaggggatc aaagagtcgg gctcataccg agaaacggtg
1561 tggaccattg ggatgcatac aaaggtgaga gagtcgtgct gtgggacgac tatggcatga
1621 gcaaccccat tcatgatgct ctgcgcatac aagaattggc tgatacgtgt ccccttacct
1681 taaattgtga cagaattgaa aataagggaa aagtttttga cagtgaagtc ataataatca
1741 caacaaacct tgccaatcca gctccacttg attatgtcaa ctttgaggcc tgttccagga
1801 gaattgactt cctggtgtac gccgaggcac cagaagtaga aaaggcaaaa cgagactttc
1861 ctggtcaacc agatatgtgg aaggacgcct tcaagtcgga cttttcacat atcaagttgc
1921 aacttgcacc tcagggcggc tttgacaaga atggcaacac cccacatggg aaaggagtga
1981 tgaagaccct caccaccggt tccctgatcg cccgtgcatc aggcttactg catgagagga
2041 tggatgaatt tgaactccaa ggccccacag tcaccacctt caactttgac cggaacagaa
2101 tcgctgcatt cagacaattg gctgcagaaa acaagtatgg attggtggac accatgagag
2161 ttggcaatca attaaaaggg gtgaaaacca tggaagcact caaacaagca atcaagaatg
2221 tgatcatcaa gaggtgccgg atcatctacg gtggctccac gtatgacctt gaatctgacg
2281 gcaagggcaa agttctggtg gaaaaggtca agaacacctc tgtacagacc aacaatgagt
2341 tggccggagc cctgcatcac ctcaaacatg cccgaatcag gtactatgtc aaatgtgtgc
2401 aagaagcagt ctactctatt atacaaatcg ccggcgctgc gtttgtcacc acacgcatag
2461 tacgccgcat gaacatacaa gagctttggt cgaagccacc attagaccaa aatgaatcag
2521 aggctaagga agaggccctc aagtcagaag atgacgagtt catcatatct tctaaggaca
2581 tcaaggagga aggaaagaag ggcaaaaaca aaactggccg tggcaagaaa catactgcat
2641 tctctagcaa gggcttgagc gatgaggagt atgacgagta caagaggata agagaagaga
2701 gaaatggaaa gtactctata gaggagtacc ttcaagacag agacaggtac tatgaggaac
2761 tcgccatcgc caaggccacg gaagaagact tctgtgagga ggaggagatc aaaatccgtc
2821 agcggatctt ccgtcccacc aggaagcaaa ggaaggaaga gagggccaca ctagggctag
2881 taactggttc agaaatcaga aaaagaaacc ctgatgactt caaacctaaa gggaaactgt
2941 gggccgatga caacagaagt gttgactaca atgagaaact ggacttcgag gcccccccaa
3001 gcatatggtc taggattgtg agttttggtt ctggttgggg cttctgggtg tcaccaagcc
3061 tgttcataac atcaactcat gtaatccctg caggcataac agaggcattt ggagtcccca
3121 tcaaacaaat ccaggtccac aaatcaggtg aattttgccg gttcagattc ccaaaaccaa
3181 ttaggtcaga tgtgacagga atgatcttgg aagaaggtgc gcctgagggc accgtggcaa
3241 ccgtgctcat caaacgccct accggagagc tcatgcccct tgcagccaga atgggaacac
3301 acgcaaccat gaaaattcag ggccgcatgg ttggcggaca gatgggtatg ttgctcactg
3361 gttcaaatgc taaaggaatg gatttgggaa caactcctgg tgattgtggc tgtccctaca
3421 tctacaaaag gggcaatgac tatatagtca ttggggtgca cacagcagca gcccgtggtg
3481 gaaacaccgt catctgtgcc acacagggaa gtgagggtga ggcaactctt gagggtggag
3541 atgacaaagg aacgtactgt ggggcaccca ttctaggccc tgggggggca ccaaaattga
3601 gcaccaaaac caaattttgg aggtcatcga acacgcctct tccaccaggg acgtatgagc
3661 ctgcctacct cggtggccgt gacccgcgtg ttaagggtgg gccctccttg cagcaggtaa
3721 tgagagacca gttgaagcca ttcactgagt ccaggggtaa acctccaaga ccaagtgtgt
3781 tggaagcagc caaacaaacc atcatcaatg tcctcgaaca aaccctggac cctccacaaa
3841 aatggacata cgcacaggcg tgtgcttcac ttgacaaaac cacctccagc gggcatcccc
3901 accacgtccg aaagaatgaa ttctggaatg gtgagacctt cactggtaaa ttggcagacc
3961 aagcatcaaa agcaaatcta atgtttgagg aagggaaaca catgacacca gtgtatacag
4021 cagccctcaa ggatgagctg gtcaagactg acaaagtcta tggaaagatc aagaagagac
4081 tgctctgggg ctctgacttg tccaccatga tccggtgcgc caggtccttt ggtgggctca
4141 tggatgagat gaaagcacac tgcatatcac tcccagtccg agttggcatg aacatgaatg
4201 aagatggtcc aataatattt gagaagcact ccagatacaa gtatcactat gatgcagatt
4261 actcccgctg ggattcaaca caacagaggg cagtattagc agcagccttg gaaatcatgg
4321 tcaggttctc tgcagagcca caattggcac aaatagtcgc tgaggatctg ctggccccca
4381 gtgtggtaga cgtaggggac tttaaaattt caataaatga agggctcccc tctggtgtac
4441 catgcacttc tcaatggaat tccatcgcac actggctgct aaccctctgt gccttgtctg
4501 aagtcaccaa actgtcccct gacattgtac aggcaaattc tatgttctca ttttacggtg
4561 atgacgagat tgtcagcacc gatataaaat tggatcctga aaagttaacc accaaattga
4621 aggagtacgg cctgaaacca actcgcccag acaaaaccga gggacccctg atcatcagtg
4681 aggatttgaa cggactcact ttcctccgga ggacggtgac tcgtgaccca gctggctggt
4741 ttggaaaatt ggaccaaagc tcaatattga ggcagatgta ctggactaga ggaccaaatc
4801 atgaagaccc caatgagaca atgatacccc actctcaaag acccatacag ctcatggcac
4861 tgcttggtga ggcctccctt cacggaccct ctttctacag caaaattagt aagttggtca
4921 taactgaact caaagaaggt ggaatggact tttacgtgcc aaggcaggaa cccatgttca
4981 ggtggatgag gttttctgac ttgagcacgt gggagggcga tcgcaatctg gctcccaatt
5041 ttgtgaatga agatggcgtc gaatgacgcc gctccatcga atgatggtgc agctagtctc
5101 gtaccagagg ccattaatga gactatgcca ttggaacccg ttgctggcgc atctattgct
5161 gccccagtgg cgggacaaac taacataatt gacccctgga taagaacaaa ttttgtgcaa
5221 gcccctaatg gagagtttac agtatcaccg agaaattccc ctggagagat tctattaaat
5281 ttagagttag gaccagattt gaatccttat ttggcccatc tatcaaggat gtacaatgga
5341 tatgctggag gtgttgaggt gcaagtgctt cttgctggga acgcgttcac agcaggaaag
5401 atattatttg cagcaattcc acccaacttt cctgtagata tgattagccc agctcaaatt
5461 actatgcttc cccatttgat tgtagatgtt aggacattgg aacctattat gataccctta
5521 cctgatgtta ggaatgtgtt ctatcatttt aataatcaac cccaacctag gatgagatta
5581 gtggctatgc tctatacccc attgagatct aatggttcag gagatgatgt ctttactgtg
5641 tcttgtagag tgttgactag gccaacccct gactttgaat tcatctacct agtgcctccc
5701 tctgtagagt ctaaaactaa accattcaca cttccaatat tgaccatttc tgaactaacc
5761 aactcccggt ttcccatccc aattgagcaa ctgtacacgg ccccaaatga gaataatgtt
5821 gtacagtgtc aaaatggaag gtgcactttg gatggagagc ttcagggcac cacccagctg
5881 ctgtcaagtg cagtttgctc ttacaggggc aggactgtgg ctaacagtgg ggacaattgg
5941 gaccagaatt tgctccagct gacctaccca agcggtgcaa gctatgaccc cactgatgaa
6001 gtaccagcac ccttgggcac ccaggatttc agtgggatat tgtatggggt gttaacccaa
6061 gacaatgtaa gtgagggtac aggggaggcc aaaaatgcta agggagtata catatccacc
6121 accagtggaa aattcacccc aaaaattggg tcaattggat tgcattcaat aactgaaaat
6181 gtgcacccca atcagcagtc acggttcacc cccgttggag tcgctcagaa tgaaaacacc
6241 cccttccagc aatgggttct accacactac gcaggtgctc tcgctctaaa caccaatttg
6301 gcacccgctg ttgccccgac tttccctggc gagcaattac tgttcttcag gtcccgtgtt
6361 ccatgtgttc aaggtctgcg ggggcaggat gctttcatag attgtctcct acctcaagag
6421 tgggtgaacc atttttatca agaggctgct ccctcccaag cagacgttgc cctcatcagg
6481 tatgtcaacc ctgatactgg tcgcacgctg tttgaggcca aattgcacag gtcaggtttc
6541 attactgtat cacacactgg tgcctaccct cttgtggtcc ccccaaatgg tcatttcagg
6601 tttgattctt gggttaacca attctactca ctcgccccca tgggaactgg caatgggcgt
6661 agaagagttc aataatggca ggagcattta tagctggtct agccggtgac atgctgactt
6721 ctgctgttgg ttcactgacc tctgcaggag ccaatgccat caatcagaaa ctgaattttg
6781 attacaataa acaactccaa aatgcatcct ttcaacatga taaggaaatg ttgcaggccc
6841 aaattgatgc tacaaagaag ctccaatcag aaatgattgc aattaagcat ggggttttga
6901 ccgcgggcgg cttttcccca gctgatgcag ccagaggggc agtcaacgcc ccaatgactc
6961 gagtgttgga ttggtcaggg acacgctact acgctccaaa ttctgtgcaa accaccagtt
7021 attctgggca attcaccccc tcgccagtcc atcgggcgca ggtgaagtcc ccttccaatt
7081 catctcagcg gactgcagct ccaagcagta tccgcagcct gtcaacccaa tcaacttctt
7141 taggctccac ctcctcaggg gggtcctcta cagcctcctc tagttcgagg acagcagact
7201 gggtgcaaca acaaagggct cttagcccgt acatgcaagg agccctgcag acggcatacg
7261 tcacaccgcc gtctagtagg gcctccagta tgagctctgt ctcaacagtg cccaaagggg
7321 ttttggactc ctggacacct gtgtttaaca cacgcaggca gccgctgttt gcacacctca
7381 ggaagagggg ggagtcacag gcttagtgaa aaggataatc aac
//