Typing tool
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Typing tool
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Complete norovirus genomes
| MW305677 | GII.7 | |
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| GII.P7 |
ORF1: 1..5032
ORF2: 5013..6635
ORF3: 6635..7408
LOCUS MW305677 7464 bp RNA linear VRL 18-JUL-2024
DEFINITION Norovirus GII isolate 11389 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MW305677
VERSION MW305677.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7464)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A.U.A., Ford-Siltz,L.A., Green,K.Y.,
Galeano,M.E., Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N.,
Ushijima,H. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses provide insights on
evolutionary dynamics and evidence of coexisting viral populations
evolving under recombination constraints
JOURNAL PLoS Pathog 17 (7), e1009744 (2021)
PUBMED 34255807
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 7464)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7464
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="11389"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Japan"
/collection_date="29-Aug-2012"
/note="genotype: GII.7[GII.P7]"
gene <1..5032
/gene="ORF1"
CDS <1..5032
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="QPJ59367.1"
/translation="NNATPSNKEEVGALSNIKVGFKKMLGAVPKGTKTPSSGQHCPTV
KIGPKTLTIPPEPPNGEDTVQFDAKSETIIGLPDLTTVQNEHENTPYTVPPLSEREHR
PATEPLPGTILEMWDGEFYHYSVYVSDGKALGVHKPPAAISLATIELTPISLYWRPVY
TPNYLVSPDTLKGLAGEKFPYTAFSNNCYNFCCWVLELNDTWLNRRCISRTTGFFKPY
QSWNRKPLPTVDDGKIKKVANAILCALGSLFSKPIKDLLGKLKPLNLLHLLASCDWTF
AGIVETVILMAELFNVFWTPPDVSNFIASLIGDFELQGPEDLAVELVPVVMGGIGMVL
GFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMKWFFPKKEEKAEMETLRAIEDA
VLDMEAIGNNHLTTLLKDKDSLTAFMKTLDLEEEKARKLSTKSSSPDIVGTINAILAR
IAAARSLLHKAKEEMFSRIRPVVVMISGRPGIGKTHMARHLAKSIANTMSGDQRVGLV
PRNGVDHWDAYRGERVVLWDDYGMGSPVKDALTLQELADTCPVTLNCDRIENKGKMFD
SDVIIITTNLVNPAPLDYVNFEACSRRVDFLVYAESPEIEKVKRDFPGQPDMWKDHFK
PDFSHIKLTLAPQGGFDKNGNTPHGKGTMRSLTQGSLTARVAGLVHERRDEFQLQGND
LQTYNFDTNRVSAFRKLAADNKYGIMETMRVGAALKNVKTLEDLKTALRDVKFNECEI
IYKNSKYRVSSNGKGSVSVDKVEDNASQTVNEVQSAILRLRQARARYYISCFQDLVYT
LIQVAGASFVVSRISRRFCWERWVKPTETQEVNESEKEVAQGRWEIEPKDTEPEGKKG
KNKKGRGKKHTAFSSKGLSDEEYDEFKRIREERNGKYSIEEYLQDRDRYYEEVAVARA
TEEDFCEEEEAKIRQRIFRPTKKQRKEERGVLGLITGSDIRKRRPDDFQPKGNLWADD
TRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSNLLITTTHVLPKGVKELFGVEIK
QIQVHKSGEFCRFRFPRPIRPDVTGLVLEEGAPEGTVCSILIKRPTGEMIPLAVRMGT
HASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDCGCPYIYKRGNDIVVAGVHTAAA
RGGNTVICATQGQDGEAVLEGNEDLGTYCGAPILGPGKAPKLSTKTKFWRSSPDALPP
GTYEPAYLGGKDPRVEKGPSLQQVMRDQLRPFTEPRGKPPRPAVLEEAKKTVMNVLEQ
TIDPAKPWSYSQACASLDKTTSSGSPHHARKNDHWNGESFTGPLADQASKANLMYEQA
KHVQPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGTMIRCARAFGGLMDSMKASCIA
LPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDSTQQRSILSAAMEVMVRFSAEPE
LAQVVAEDLLAPSQLDVGDFVISVQEGLPSGVPCTSQWNSIAHWILTLSAMAEVSGLS
PDVVQAHSCFSFYGDDEIVSTDINLDPMKLTQKLREYGLVPTRPDKTEGPLVITEDLT
GLTFLRRSIARDPAGWFGKLDQDSILRQLYWTRGPNHENPYESMVPHSQRATQLMALL
GEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEAMFRWMRFSDLSTWEGDRNLAPE
GVNEDGVE"
mat_peptide <1..940
/gene="ORF1"
/product="p48"
mat_peptide 941..2038
/gene="ORF1"
/product="NTPase"
mat_peptide 2039..2557
/gene="ORF1"
/product="p22"
mat_peptide 2558..2956
/gene="ORF1"
/product="VPg"
mat_peptide 2957..3499
/gene="ORF1"
/product="Pro"
mat_peptide 3500..5029
/gene="ORF1"
/product="RdRp"
gene 5013..6635
/gene="ORF2"
CDS 5013..6635
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ59368.1"
/translation="MKMASNDAAPSNDGAAGLVPEINNEVMPLEPVAGASLATPVVGQ
QNIIDPWIRNNFVQAPAGEFTVSPRNSPGEILLDLELGPELNPYLAHLARMYNGHAGG
MEVQIVLAGNAFTAGKIIFAAIPPGFPYENLSPSQITMCPHVIIDVRQLEPVLLPMPD
IRNNFFHYNQGNDPKLRLIAMLYTPLRANNSGDDVFTVSCRVLTKPSPDFEFTFLVPP
TVESKTKQFTLPILKISEMTNSRFPVPVEMMYTARNENQVVQPQNGRVTLDGELLGTT
PLLAVNICKFKGEVIAKNGDVRSYRMDMEITNTDGTPIDPTEDTPGPIGSPDFQGILF
GVASQRNKNEQNPATRAHEANINTGGDQYAPKLAQVKFFSESQDFEVHQPTVFTPVGV
AGDTSHPFRQWVLPRYGGHLTNNTHLAPAVAPLFPGEQILFFRSQIPSSGGHELGYMD
CLVPQEWVQHFYQEAATAQSEVALIRFINPDTGRVLFEAKLHKQGFITVAHTGDNPIV
MPPNGYFRFEAWVNQFYSLAPVGTGNGRRRIQ"
gene 6635..7408
/gene="ORF3"
CDS 6635..7408
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ59369.1"
/translation="MASAFLANLAGGVASNGISSLINAGANAINQKVEFDYNKQLQNA
SFSHDKEMLQAQIEATKRLQQEMIDIKQGVLTAAGFSPTDAARGSVGAPMTKLVDWSG
TRYWAPGAMRTTGYSGTFTHLPPVQSASYVNNQNRQFLKVDPSPPSSSGSSVSSVKTQ
STTLSGTSRVGSSSQSTLSTRPSTRTSDWVRSQNERLSPFMDGALQTTYVTPPSSRAS
NVSTVSTVPKEVLDSWTPMFNTHRQPLFAHLRRRGESQV"
ORIGIN
1 taataatgcc accccttcta acaaagaaga ggttggtgca ttatccaaca tcaaagttgg
61 attcaagaaa atgctgggtg ccgtacccaa gggtaccaaa acacccagca gtggtcaaca
121 ttgccccaca gttaagatcg ggcctaaaac attaacaatc ccccctgagc ccccaaatgg
181 tgaagacacc gtacagtttg acgcaaagtc agaaactata attgggttgc cagacttaac
241 aacggtgcaa aatgaacatg aaaacacccc atacactgtc cctccattaa gtgagaggga
301 gcacagaccg gccactgaac cacttcctgg cacaatactg gagatgtggg atggtgagtt
361 ttaccactac tccgtgtacg tcagcgacgg caaagctctg ggggtccaca aaccaccggc
421 ggctataagc ctcgcgacga tagagctcac ccccatatca ctttactgga ggcccgttta
481 tacccccaac tacttggtct cccctgacac attaaagggc ctcgctggtg agaagttccc
541 ctacacggcc ttcagtaaca actgttacaa cttctgttgc tgggtgctag agctcaacga
601 cacgtggctt aacagaagat gcatttccag aactaccggc ttcttcaaac cataccagtc
661 ttggaacagg aaacctctcc caaccgttga tgatggaaag atcaaaaaag tggccaacgc
721 gatcctctgc gcactcggct cgctgttctc aaaaccaatc aaagacctat taggcaaact
781 caagccattg aacctactgc acttgcttgc gtcttgtgat tggacgtttg cgggtatagt
841 ggagacagtc atcttgatgg cagagctttt caatgtcttc tggaccccgc cagatgtctc
901 taattttata gcctccctaa taggtgattt tgaattgcaa gggcctgaag acctggctgt
961 ggagctcgtc cccgtggtta tgggcggcat agggatggtt ctcggtttca ccgctgagaa
1021 gataggccgc atgctgtcgt ccgctgcatc aacactgcgg gcgtgcaaag acctagggaa
1081 ctatgccctt gacatactca aattggtcat gaagtggttc ttcccaaaga aagaagagaa
1141 agctgagatg gaaaccttga gggcaatcga agatgccgtc ctggatatgg aagctatagg
1201 gaataaccac ctcacaaccc ttctcaagga caaagacagc ctcacggctt tcatgaagac
1261 cctggatctg gaggaggaga aggcgaggaa actgtccact aaatcatctt caccggacat
1321 agttggcacc atcaatgcca tactggctag gatagctgct gctagatccc ttctacataa
1381 ggccaaagag gagatgttca gcaggatcag gccagtggtc gtgatgatct caggcaggcc
1441 tggcattgga aagacccaca tggcgagaca tttggctaag agcatcgcca acaccatgag
1501 tggcgaccag agagtcgggc tcgttccgcg caacggtgtc gaccactggg atgcctacag
1561 gggagagagg gtggtcttgt gggatgacta cggtatgggg agccctgtta aagacgccct
1621 aacactgcaa gagctggccg acacatgtcc agtcacttta aattgtgata ggattgagaa
1681 taaggggaag atgtttgaca gtgatgtcat cataatcacg accaacctag tcaaccccgc
1741 gccccttgac tatgtgaact tcgaggcgtg ttctaggagg gttgacttcc tggtctatgc
1801 agagtcacca gaaattgaaa aggtcaagag ggacttccct ggccagcctg atatgtggaa
1861 agaccacttt aagccagact tctcccacat caagctgacc ctagcccccc agggggggtt
1921 tgacaaaaat ggcaacaccc cacacggcaa gggtaccatg cggtccctaa cccaggggtc
1981 cctgactgcg agagttgcag gcctcgtcca tgagaggaga gatgaattcc agctccaagg
2041 aaatgacctc caaacataca actttgacac caacagagtc tccgcattca ggaaattggc
2101 tgcagataac aagtatggga tcatggagac gatgagagtg ggtgcggcac tcaagaatgt
2161 gaagaccctg gaagatctta aaactgcatt gagggatgta aaattcaatg agtgtgaaat
2221 aatttacaag aactctaagt atcgagtctc ttccaatggt aaaggttcag tttctgttga
2281 taaagttgag gacaatgcat cccagactgt aaacgaggta caatcagcaa ttctcaggct
2341 caggcaagcg agggccagat attatatcag ctgtttccaa gacctcgtct acactctcat
2401 acaggttgcc ggagcatcat tcgttgtcag caggatctcc agaaggtttt gctgggaaag
2461 gtgggtcaaa ccgaccgaga cccaggaggt gaatgagtcc gaaaaggaag tggcacaagg
2521 cagatgggaa attgagccca aggacacaga accagaaggc aagaagggta agaacaagaa
2581 aggaaggggc aagaaacaca cagctttctc tagcaaaggc ctgagtgatg aagagtatga
2641 cgagttcaag agaatcaggg aggaaaggaa cggaaagtat tccattgagg aatacctgca
2701 agaccgggac cgctattatg aagaagtggc agttgcccgg gcaacagagg aggacttctg
2761 tgaagaggaa gaggccaaga taagacaaag aattttccgc ccgacaaaga aacagaggaa
2821 ggaggaaagg ggtgtgcttg gcttaatcac cggctcagac atcagaaaga ggagaccaga
2881 tgacttccaa ccaaaaggca acctatgggc agatgacacc aggagtgtgg actacaatga
2941 gaggcttgac tttgaagcgc ccccgagtgt ctggtcaaga atagtcccat taggcactgg
3001 ttggggattc tgggtttcat ccaaccttct gatcacaaca acacacgtcc tgcctaaagg
3061 ggttaaggag ctctttggag ttgaaatcaa gcaaatccaa gttcacaagt ctggagagtt
3121 ttgcaggttt agattcccaa gacctatcag gccagatgtc acaggactcg tactggagga
3181 aggcgcccca gaaggcactg tctgttctat actcataaaa agacccacag gtgagatgat
3241 ccccttggca gtgaggatgg gcacacatgc atccatgaaa atacagggca ggactgttgg
3301 tggccagatg ggaatgcttc tcacaggagc aaacgcgaag aacatggacc tcggcaccgg
3361 tcctggtgac tgcggttgcc cctacatcta caaacgtggc aacgacattg ttgtcgcggg
3421 tgttcacacc gcagcagccc ggggaggcaa cactgttata tgtgccaccc aagggcaaga
3481 tggggaagca gtccttgagg gaaatgagga ccttggcacc tattgtggcg ccccgattct
3541 gggccctggc aaggcgccta aactcagcac aaagaccaag ttttggcgct catcaccaga
3601 tgccttgcca cctggcacat atgaacctgc ttacttagga ggcaaagacc ctagagtgga
3661 aaaaggtccc tccctgcaac aagtcatgag agaccagttg agacccttca cagaacccag
3721 gggcaaacca cctagacctg cagtcttgga ggaagccaaa aagacagtga tgaatgttct
3781 agaacaaacc attgaccccg ccaagccatg gtcctattcg caggcatgtg cctcactgga
3841 caaaaccacc tctagtggta gcccccatca cgctaggaaa aatgaccact ggaatgggga
3901 gtccttcact ggtccacttg cagatcaggc atctaaagcc aacctcatgt atgagcaggc
3961 caaacatgtg cagcccgtgt atacggccgc gctcaaagat gagcttgtta agactgacaa
4021 gatctacaag aagataaaga agaggctcct atgggggtcg gaccttggca caatgatcag
4081 gtgtgccagg gcttttggtg gtctcatgga cagcatgaag gcaagttgta tagctcttcc
4141 ttgcagggta ggaatgaaca tgaatgaaga tggccccatt atatttgata aacattctaa
4201 gtacaggtac cactatgatg ctgactattc taggtgggat tcaactcaac aaaggagcat
4261 tctttctgcc gctatggaag taatggtgcg gttctctgct gaaccagaat tggcacaagt
4321 ggttgcagag gaccttttgg cacctagcca gcttgatgtc ggcgattttg tcatttcagt
4381 ccaggagggt ctgccatcag gagtcccatg cacatcacaa tggaactcaa tagcacactg
4441 gatcctaact ttgagtgcaa tggcagaagt gtcaggtctc tcaccagatg ttgtccaagc
4501 tcactcctgt ttttcatttt atggggacga tgagattgtc agtactgata tcaaccttga
4561 ccccatgaag ttgacacaga aactcaggga gtatggtctg gtccccaccc ggcctgacaa
4621 aactgaaggt cccctagtca taactgaaga cctcactggc ctgacgttcc tccgtaggtc
4681 gattgcccgg gacccagctg gttggtttgg aaagctggac caagactcga tcctgaggca
4741 gctgtactgg acaagggggc ctaaccacga gaacccgtac gagagcatgg ttcctcattc
4801 tcagcgggcc acacaactca tggcccttct tggtgaggcc tcactgcatg gtccccagtt
4861 ttacaagaaa gttagcaaga tggtcatcaa tgagatcaag agtggtggtc tggagtttta
4921 tgtgcccaga caagaggcca tgttcaggtg gatgagattc tctgacctca gcacatggga
4981 gggcgatcgc aatcttgctc ccgaaggtgt gaatgaagat ggcgtcgaat gacgcagctc
5041 catctaatga tggtgcagca ggcctcgtgc cagagatcaa caatgaggtc atgccccttg
5101 agcccgtggc tggtgcatcg ctggcgacac cagttgtcgg gcaacaaaat ataattgatc
5161 cctggataag aaataatttt gtacaagctc ctgcaggtga gttcacagtt tcccctagaa
5221 attcccctgg tgaaatttta cttgatttgg agttgggacc agaactgaac ccctatctcg
5281 ctcatctggc ccgtatgtac aatgggcacg ctggtggcat ggaagtgcaa attgtgctag
5341 ctgggaacgc gttcacagct ggcaagatca tatttgctgc catccctcca gggttcccat
5401 atgaaaattt gtcaccttca caaatcacaa tgtgccctca tgttataatt gatgttagac
5461 aattagaacc agttctatta cctatgccag atattagaaa taacttcttc cattacaatc
5521 agggcaatga cccaaaattg agattgatag ctatgctcta caccccttta agggctaaca
5581 attctggtga tgatgtgttt acagtttctt gtagggttct caccaaaccg tcacctgatt
5641 ttgaattcac atttttggtc ccccctacgg ttgaatctaa gaccaaacag ttcacattac
5701 ccatcctcaa aatatcagag atgaccaact caagattccc agtgccagtg gaaatgatgt
5761 atacagccag gaatgagaac caagttgtcc agccacagaa tggtagggtc acactcgatg
5821 gcgagctatt aggcaccaca cccctgttgg ctgtcaacat ctgcaaattc aagggggagg
5881 ttatagctaa gaatggagat gtgagatcct ataggatgga catggaaatt accaacactg
5941 atggcacccc aattgacccc acagaagaca caccaggtcc cattggttca cctgactttc
6001 aaggtatact ctttggcgtt gccagccaac gcaacaagaa tgagcaaaac cctgccacga
6061 gagcccatga agccaacatt aacactggtg gggaccaata tgcccccaaa ttggcccaag
6121 tgaaattctt ctcagagtcc caggatttcg aggtgcacca gcccacagtt ttcaccccag
6181 ttggtgtggc aggcgacact tcccaccctt tcagacagtg ggtcctgcct cgatacggtg
6241 gacatctcac caacaacacc cacttggctc cagcagtggc ccccctattc ccaggtgagc
6301 agatcctatt ctttagatca caaataccca gctcaggcgg ccatgaatta ggttacatgg
6361 actgccttgt cccacaagaa tgggtccaac acttctatca agaagctgcc acagctcagt
6421 ctgaggtggc actcataagg ttcatcaacc cagacactgg cagagtcctc tttgaggcca
6481 agctgcacaa gcaaggcttt ataactgtgg ctcacactgg tgataaccca attgttatgc
6541 caccaaatgg gtactttaga tttgaagcct gggttaatca gttttactca ctcgcccccg
6601 tgggaactgg gaatgggcgc aggaggatcc aataatggct agtgctttcc ttgcaaattt
6661 ggcaggaggc gttgcctcca atgggattag ttcactcata aatgctgggg ctaatgctat
6721 taaccaaaag gttgagtttg attataataa acaactccaa aatgcatcct tctcccatga
6781 taaggaaatg ctccaagccc aaattgaagc cactaaacgt ctgcaacaag agatgattga
6841 cataaagcaa ggggtgctga cagctgcggg attctctcct acagatgccg cgaggggttc
6901 tgtcggcgcg ccaatgacaa aattagttga ttggagtggc actagatatt gggcgcctgg
6961 tgccatgagg acaacaggct attcagggac ttttactcac ttgccccctg tgcagtctgc
7021 ttcatatgtt aataatcaaa atagacaatt tcttaaagta gacccttctc ctccttcttc
7081 gagtggttct tctgtttctt ctgtcaaaac acaatcaact accctctcag gcacttcaag
7141 ggtgggctct tcatctcagt caaccctgtc gaccaggccg agcacaagga catctgattg
7201 ggtgcgcagc cagaatgaaa ggttgagtcc ctttatggat ggagcgttgc aaacaacgta
7261 tgtaacgcca ccatccagta gggcatcaaa tgtcagcaca gtctcgaccg tgccgaaaga
7321 ggttttggac tcctggacgc ctatgtttaa tactcacagg cagccactct tcgcccattt
7381 gcgtaggcga ggggagtcac aggtttagtg aaaagattgg ttaggaaagt tgattagttt
7441 gttcttcttt tctactattc cttt
//