Typing tool
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Typing tool
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Complete norovirus genomes
| MW305675 | GII.7 | |
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| GII.P7 |
ORF1: 1..5031
ORF2: 5012..6634
ORF3: 6634..7407
LOCUS MW305675 7463 bp RNA linear VRL 18-JUL-2024
DEFINITION Norovirus GII isolate 11157 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MW305675
VERSION MW305675.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7463)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A.U.A., Ford-Siltz,L.A., Green,K.Y.,
Galeano,M.E., Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N.,
Ushijima,H. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses provide insights on
evolutionary dynamics and evidence of coexisting viral populations
evolving under recombination constraints
JOURNAL PLoS Pathog 17 (7), e1009744 (2021)
PUBMED 34255807
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 7463)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7463
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="11157"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Japan"
/collection_date="19-Nov-2012"
/note="genotype: GII.7[GII.P7]"
gene <1..5031
/gene="ORF1"
CDS <1..5031
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QPJ59361.1"
/translation="NNAAPSNKEEVGALSNIKVGFKKMLGVVPKGTKTPSSGQHCPTV
KIGPKTLTIPPEPPNGEDTVQFDAKSETIIGLPDLTTVQNEHENTPYTVPPLSEREHR
PATEPLPGTILEMWDGEFYHYSVYVSDGKALGVHKPPAAISLATIELTPISLYWRPVY
TPNYLVSPDTLKGLAGEKFPYTAFSNNCYNFCCWVLELNDTWLNRRCISRTTGFFKPC
QSWNRKPLPTVDDGKIKKVANAILCALGSLFSKPIKDLLGKLKPLNLLHLLASCDWTF
AGIVETVILMAELFNVFWTPPDVSNFIASLIGDFELQGPEDLAVELVPVVMGGIGMVL
GFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMKWFFPKKEEKAEMETLRAIEDA
VLDMEAIGNNHLTTLLKDKDSLTAFMKTLDLEEEKARKLSTKSSSPDIVGTINAILAR
IAAARSLLHKAKEEMFSRIRPVVVMISGRPGIGKTHMARHLAKSIANTMSGDQRVGLV
PRNGVDHWDAYRGERVVLWDDYGMGSPVKDALTLQELADTCPVTLNCDRIENKGKMFD
SDVIIITTNLVNPAPLDYVNFEACSRRVDFLVYAESPEIEKVKRDFPGQPDMWKDHFK
PDFSHIKLTLAPQGGFDKNGNTPHGKGTMRSLTQGSLTARVAGLVHERRDEFQLQGND
LQTYNFDTNRVSAFRKLAADNKYGIMETMRVGAALKNVKTLEDLKTALRDVKFNECEI
IYKNSKYRVSSNGKGSVSVDKVEDNASQTVNEVQSAILRLRQARARYYISCFQDLVYT
LIQVAGASFVVSRISRRFCWERWVKPTETQEVNESEKEVAQGRWEIEPKDTEPEGKKG
KNKKGRGKKHTAFSSKGLSDEEYDEFKRIREERNGKYSIEEYLQDRDRYYEEVAVARA
TEEDFCEEEEAKIRQRIFRPTKKQRKEERGVLGLITGSDIRKRRPDDFQPKGNLWADD
TRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSNLLITTTHVLPKGVKELFGVEIK
QIQVHKSGEFCRFRFPRPIRPDVTGLVLEEGAPEGTVCSILIKRPTGEMIPLAVRMGT
HASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDCGCPYIYKRGNDIVVAGVHTAAA
RGGNTVICATQGQDGEAVLEGNEDLGTYCGAPILGPGKAPKLSTKTKFWRSSPDALPP
GTYEPAYLGGKDPRVEKGPSLQQVMRDQLRPFTEPRGKPPRPAVLEEAKKTVMNVLEQ
TIDPAKPWSYSQACASLDKTTSSGNPHHARKNDHWNGESFTGPLADQASKANLMYEQA
KHVQPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGTMIRCARAFGGLMDSMKASCIA
LPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDSTQQRSILSAAMEVMVRFSAEPE
LAQVVAEDLLAPSQLDVGDFVISVQEGLPSGVPCTSQWNSIAHWILTLSAMAEVSGLS
PDVVQAHSCFSFYGDDEIVSTDINLDPMKLTQKLREYGLVPTRPDKTEGPLVITEDLT
GLTFLRRSIARDPAGWFGKLDQDSILRQLYWTRGPNHENPYESMVPHSQRATQLMALL
GEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEAMFRWMRFSDLSTWEGDRNLAPE
GVNEDGVE"
mat_peptide <1..939
/gene="ORF1"
/product="p48"
mat_peptide 940..2037
/gene="ORF1"
/product="NTPase"
mat_peptide 2038..2556
/gene="ORF1"
/product="p22"
mat_peptide 2557..2955
/gene="ORF1"
/product="VPg"
mat_peptide 2956..3498
/gene="ORF1"
/product="Pro"
mat_peptide 3499..5028
/gene="ORF1"
/product="RdRp"
gene 5012..6634
/gene="ORF2"
CDS 5012..6634
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ59362.1"
/translation="MKMASNDAAPSNDGAAGLVPEINNEVMPLEPVAGASLATPVVGQ
QNIIDPWIRNNFVQAPTGEFTVSPRNSPGEILLDLELGPELNPYLAHLARMYNGHAGG
MEVQIVLAGNAFTAGKIIFAAIPPGFPYENLSPSQITMCPHVIIDVRQLEPVLLPMPD
IRNNFFHYNQGNDPKLRLIAMLYTPLRANNSGDDVFTVSCRVLTKPSPDFEFTFLVPP
TVESKTKQFTLPILKISEMTNSRFPVPVEMMYTARNENQVVQPQNGRVTLDGELLGTT
PLLAVNICKFKGEVIAKNGDVRSYRMDMEITNTDGTPIDPTEDTPGPIGSPDFQGILF
GVASQRNKNEQNPATRAHEANINTGGDQYAPKLAQVKFFSESQDFEVHQPTVFTPVGV
AGDTSHPFRQWVLPRYGGHLTNNTHLAPAVAPLFPGEQILFFRSQIPSSGGHELGYMD
CLVPQEWVQHFYQEAATAQSEVALIRFINPDTGRVLFEAKLHKQGFITVAHTGDNPIV
MPPNGYFRFEAWVNQFYSLAPVGTGNGRRRIQ"
gene 6634..7407
/gene="ORF3"
CDS 6634..7407
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ59363.1"
/translation="MASAFLASLAGGVASNGISSLINAGANAINQKVEFDYNKQLQNA
SFSHDKEMLQAQIEATKRLQQEMIDIKQGVLTDAGFSPTDAARGSVGAPMTKLVDWSG
TRYWAPGAMRTTGYSGTFTHLPPVQSASYVNNQNRQFLKVDPSPPSSSGSSVSSVKTQ
STTLSGTSRVGSSSQSTLSTRPSTRTSDWVRSQNERLSPFMDGALQTTYVTPPSSRAS
NVSTVSTVPKEVLDSWTPMFNTHRQPLFAHLRRRGESQV"
ORIGIN
1 aataatgccg ccccttctaa caaagaagag gttggtgcat tatccaacat caaagttgga
61 ttcaagaaaa tgctgggtgt cgtacccaag ggtaccaaaa cacccagcag tggtcaacat
121 tgccccacag ttaagatcgg gcctaaaaca ttaacaatcc cccctgagcc cccaaatggt
181 gaagacaccg tacagtttga cgcaaagtca gaaactataa ttgggttgcc agacttaaca
241 acggtgcaaa atgaacatga aaacacccca tacactgtcc ctccattaag tgagagggag
301 cacagaccgg ccactgaacc acttcctggc acaatactgg agatgtggga tggtgagttt
361 taccactact ccgtgtacgt cagcgacggc aaagctctgg gggtccacaa accaccggcg
421 gctataagcc tcgcgacgat agagctcacc cccatatcac tttactggag gcccgtttat
481 acccccaact acttggtctc ccctgacaca ttaaagggcc tcgctggtga gaagttcccc
541 tacacggcct tcagtaacaa ctgttacaac ttctgttgct gggtgttaga gctcaacgac
601 acgtggctta acagaagatg tatttccaga actaccggct tcttcaaacc atgccagtct
661 tggaacagga aacctctccc aaccgttgat gatggaaaaa tcaaaaaagt ggccaacgcg
721 atcctctgcg cactcggctc gctgttctca aaaccaatca aagacctatt aggcaaactc
781 aagccattga acctactgca cttgcttgcg tcttgtgatt ggacgtttgc gggtatagtg
841 gagacagtca tcttgatggc agagcttttc aatgtcttct ggaccccgcc agatgtctct
901 aattttatag cctccctaat aggtgatttt gaattgcaag ggcctgaaga cctggctgtg
961 gagctcgtcc ccgtggttat gggcggcata gggatggtcc tcggtttcac cgctgagaag
1021 ataggccgca tgctatcgtc cgctgcatca acactgcggg cgtgcaaaga cctagggaac
1081 tatgcccttg acatactcaa attggtcatg aagtggttct tcccaaagaa agaagagaaa
1141 gctgagatgg aaaccttgag ggcaatcgaa gatgccgtcc tggatatgga agctataggg
1201 aataaccacc tcacaaccct tctcaaggac aaagacagcc tcacggcttt catgaagacc
1261 ctggatctgg aggaggagaa ggcgaggaaa ctgtccacta aatcatcttc accggacata
1321 gttggcacca tcaatgccat actggctagg atagctgctg ctagatccct tctacataag
1381 gccaaagagg agatgttcag caggatcagg ccagtggtcg tgatgatctc aggcaggcct
1441 ggcattggaa agacccacat ggcgagacat ttggctaaga gcatcgccaa caccatgagt
1501 ggcgaccaga gagtcgggct cgttccgcgc aacggtgtcg accactggga tgcctacagg
1561 ggagagaggg tggtcttgtg ggatgactac ggtatgggga gccctgttaa agacgcccta
1621 acactgcaag agctggccga cacatgtcca gtcactttaa attgtgatag gattgagaat
1681 aaggggaaga tgtttgacag tgatgtcatc ataatcacga ccaacctagt caaccccgcg
1741 ccccttgact atgtgaactt cgaggcgtgt tctaggaggg ttgacttcct ggtctatgca
1801 gagtcaccag aaattgaaaa ggtcaagagg gacttccctg gccagcctga tatgtggaaa
1861 gaccacttta agccagactt ctcccacatc aagctgaccc tagcccccca gggggggttt
1921 gacaaaaatg gcaacacccc acacggcaag ggtaccatgc ggtccctaac ccaggggtcc
1981 ctgactgcga gagttgcagg cctcgtccat gagaggagag atgaattcca gctccaagga
2041 aatgacctcc aaacatacaa ctttgacacc aacagagtct ccgcattcag gaaattggct
2101 gcagataaca agtatgggat catggagacg atgagagtgg gtgcggcact caagaatgtg
2161 aagaccctgg aagatcttaa aactgcattg agggatgtaa aattcaatga gtgtgaaata
2221 atttacaaga actctaagta tcgagtctct tccaatggta aaggttcagt ttctgttgat
2281 aaagttgagg acaatgcatc ccagactgta aacgaggtac aatcagcaat tctcaggctc
2341 aggcaagcga gggccagata ttacatcagc tgtttccaag acctcgtcta cactctcata
2401 caggttgccg gagcatcatt cgttgtcagc aggatctcca gaaggttttg ctgggaaagg
2461 tgggtcaaac cgaccgagac ccaggaggtg aatgagtccg aaaaggaagt ggcacaaggc
2521 agatgggaaa ttgagcccaa ggacacagaa ccagaaggca agaagggtaa gaacaagaaa
2581 ggaaggggca agaaacacac agctttctct agcaaaggcc tgagtgatga agagtatgac
2641 gagttcaaga gaatcaggga ggaaaggaac ggaaagtatt ccattgagga atacctgcaa
2701 gaccgggacc gctattatga agaagtggca gttgcccggg caacagagga ggacttctgt
2761 gaagaggaag aggccaagat aagacaaaga attttccgcc cgacaaagaa acagaggaag
2821 gaggaaaggg gtgtgcttgg cttaatcacc ggctcagaca tcagaaagag gagaccagat
2881 gacttccaac caaaaggcaa cctatgggca gatgacacca ggagtgtgga ctacaatgag
2941 aggcttgact ttgaagcgcc cccgagtgtc tggtcaagaa tagtcccatt aggcactggt
3001 tggggattct gggtttcatc caaccttctg atcacaacaa cacacgtcct gcctaaaggg
3061 gttaaggagc tctttggagt tgaaatcaag caaatccaag ttcacaagtc tggagagttt
3121 tgcaggttta gattcccaag acctatcagg ccagatgtca caggactcgt actggaggaa
3181 ggcgccccag aaggcactgt ctgttctata ctcataaaaa gacccacagg tgagatgatc
3241 cccttggcag tgaggatggg cacacatgca tccatgaaaa tacagggcag gactgttggt
3301 ggccagatgg gaatgcttct cacaggagca aacgcgaaga acatggacct cggcaccggt
3361 cctggtgact gcggttgccc ctacatctac aaacgtggca acgacattgt tgtcgcgggt
3421 gttcacaccg cagcagcccg gggaggcaac actgttatat gtgccaccca agggcaagat
3481 ggggaagcag tccttgaggg aaatgaggac cttggcacct attgtggcgc cccgattctg
3541 ggccctggca aggcgcctaa actcagcaca aagaccaagt tttggcgctc atcaccagat
3601 gccttgccac ctggcacata tgaacctgct tacttaggag gcaaagaccc tagagtggaa
3661 aaaggtccct ccctgcaaca agtcatgaga gaccagttga gacccttcac agaacccagg
3721 ggcaaaccac ctagacctgc agtcttggag gaagccaaaa agacagtgat gaatgttcta
3781 gaacaaacca ttgaccccgc caagccatgg tcctattcgc aggcatgtgc ctcactggac
3841 aagaccacct ctagtggtaa cccccatcac gctaggaaaa atgaccactg gaatggggag
3901 tccttcactg gtccacttgc agatcaggca tctaaagcca acctcatgta tgagcaggcc
3961 aaacatgtgc agcccgtgta tacggccgcg ctcaaagatg agcttgttaa gactgacaag
4021 atctataaga agataaagaa gaggctccta tgggggtcgg accttggcac aatgatcagg
4081 tgtgccaggg cttttggtgg tctcatggac agcatgaagg caagttgtat agctcttcct
4141 tgcagggtag gaatgaacat gaatgaagat ggccccatta tatttgataa acattctaag
4201 tacaggtacc actatgatgc tgactattct aggtgggatt caactcaaca aaggagcatt
4261 ctttctgccg ctatggaagt aatggtgcgg ttctctgctg aaccagaatt ggcacaagtg
4321 gttgcagagg accttttggc acctagccag cttgatgtcg gcgattttgt catttcagtc
4381 caggagggtc tgccatcagg agtcccatgc acatcacaat ggaactcaat agcacactgg
4441 atcctaactt tgagcgcaat ggcagaagtg tcaggtctct caccagatgt tgtccaagct
4501 cactcctgtt tttcatttta tggggacgat gagattgtca gtactgatat caaccttgac
4561 cccatgaagt tgacacagaa actcagggag tatggtctgg tccccacccg gcctgacaaa
4621 actgaaggtc ccctagtcat aactgaagac ctcactggcc tgacgttcct ccgtaggtcg
4681 attgcccggg acccagctgg ttggtttgga aagctggacc aagactcgat cctgaggcag
4741 ctgtactgga caagggggcc taaccatgag aacccgtacg agagcatggt tcctcattct
4801 cagcgggcca cacaactcat ggcccttctt ggtgaggcct cactgcatgg tccccagttt
4861 tacaagaaag ttagcaagat ggtcatcaat gagatcaaga gtggtggtct ggagttttat
4921 gtgcccagac aagaggccat gttcaggtgg atgagattct ctgacctcag cacatgggag
4981 ggcgatcgca atcttgctcc cgaaggtgtg aatgaagatg gcgtcgaatg acgcagctcc
5041 atctaatgat ggtgcagcag gcctcgtgcc agagatcaac aatgaggtca tgccccttga
5101 gcccgtggct ggtgcatcgc tggcgacacc agttgtcggg caacaaaata taattgatcc
5161 ctggataaga aataattttg tacaagctcc tacaggtgag ttcacagttt cccctagaaa
5221 ttcccctggt gaaattttac ttgatttgga gttgggacca gaactgaacc cctatctcgc
5281 tcatctggcc cgcatgtaca atgggcacgc tggtggcatg gaagtgcaaa ttgtgctagc
5341 tgggaacgcg ttcacagctg gcaagatcat atttgctgcc atccctccag ggttcccata
5401 tgaaaatttg tcaccttcac aaatcacaat gtgccctcat gttataattg atgttagaca
5461 attagaacca gttctattac ctatgccaga tattagaaat aacttcttcc attacaatca
5521 gggcaatgac ccaaaattga gattgatagc tatgctctac acccctttaa gggctaacaa
5581 ctctggtgat gatgtgttta cagtttcttg tagggttctc accaaaccgt cacctgattt
5641 tgaattcaca tttttggtcc cccctacggt tgaatctaag accaaacagt tcacattacc
5701 catcctcaaa atatcagaga tgaccaactc aagattccca gtgccagtgg aaatgatgta
5761 tacagccagg aatgagaacc aagttgtcca gccacagaat ggtagggtca cactcgatgg
5821 cgagctatta ggcaccacac ccctgttggc tgtcaacatc tgcaaattca agggggaggt
5881 tatagctaag aatggagatg tgagatccta taggatggac atggaaatta ccaacactga
5941 tggcacccca attgacccca cagaagacac accaggtccc attggttcac ctgactttca
6001 aggtatactc tttggcgttg ccagccaacg caacaagaat gagcaaaacc ctgccacgag
6061 agcccatgaa gccaacatta acactggtgg ggaccaatat gcccccaaat tggcccaagt
6121 gaaattcttc tcagagtccc aggatttcga ggtgcaccag cccacagttt tcaccccagt
6181 tggtgtggca ggcgacactt cccacccttt cagacagtgg gtcctgcctc gatacggtgg
6241 acatctcacc aacaacaccc acttggctcc agcagtggcc cccctattcc caggtgagca
6301 gatcctattc tttagatcac aaatacccag ctcaggcggc catgaattag gttacatgga
6361 ctgccttgtc ccacaagaat gggtccaaca cttctatcaa gaagctgcca cagctcagtc
6421 tgaggtggca ctcataaggt tcatcaaccc agacactggc agagtcctct ttgaggccaa
6481 gctgcacaag caaggcttta taactgtggc tcacactggt gataacccaa ttgttatgcc
6541 accaaatggg tactttagat ttgaagcctg ggttaatcag ttttactcac tcgcccccgt
6601 gggaactggg aatgggcgca ggaggatcca ataatggcta gtgctttcct tgcaagtttg
6661 gcaggaggcg ttgcctccaa tgggattagt tcactcataa atgctggggc taatgctatt
6721 aaccaaaagg ttgagtttga ttataataaa caactccaaa atgcatcctt ctcccatgat
6781 aaggaaatgc tccaagccca aattgaagcc actaaacgtc tgcaacaaga gatgattgac
6841 ataaagcaag gggtgctgac agatgcggga ttctctccta cagatgccgc gaggggttct
6901 gtcggcgcgc caatgacaaa attagttgat tggagtggca ctagatattg ggcgcctggt
6961 gccatgagga caacaggcta ttcagggact tttactcact tgccccctgt gcagtctgct
7021 tcatatgtta ataatcaaaa tagacaattt cttaaagtag acccttctcc tccttcttcg
7081 agtggttctt ctgtttcttc tgtcaaaaca caatcaacta ccctctcagg cacttcaagg
7141 gtgggctctt catctcagtc aaccctgtcg accaggccga gcacaaggac atctgattgg
7201 gtgcgcagcc agaatgaaag gttgagtccc tttatggatg gagcgttgca aacaacgtat
7261 gtaacgccac catccagtag ggcatcaaat gtcagcacag tctcgaccgt gccgaaagag
7321 gttttggact cctggacgcc tatgtttaat actcacaggc agccactctt cgcccatttg
7381 cgtaggcgag gggagtcaca ggtttagtga aaagattggt taggaaagtt gattagtttg
7441 ttcttctttt ctactattcc ttt
//