Typing tool
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Typing tool
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Complete norovirus genomes
| MW305672 | GII.14 | |
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| GII.P7 |
ORF1: 1..5060
ORF2: 5041..6651
ORF3: 6651..7445
LOCUS MW305672 7490 bp RNA linear VRL 06-JUL-2021
DEFINITION Norovirus GII isolate 11085 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MW305672
VERSION MW305672.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7490)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses reveal coexistence of
viral populations evolving under recombination constraints
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7490)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7490
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="11085"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Japan"
/collection_date="23-Jan-2012"
/note="genotype: GII.14[GII.P7]"
gene <1..5060
/gene="ORF1"
CDS <1..5060
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QPJ59352.1"
/translation="FGSQNSVNDSINATPSNKEEVGAFSNIKVGFKKMLGAVPKSTRA
PSSGQHCPTVKIGPKTLTIPPEPPNEDTVQFDAKSETIIGLPDLTTVQNEHENTPYTV
PPLSEREHRSATEPLPGTILEMWDGEFYHYSVYVSDGKALGVHKPPAAISLATIELTP
ISLYWRPVYTPNYLVSPDTLKGLAGEKFPYTAFSNNCYNFCCWVLELNDTWLNRRCIS
RTTGFFKPYQSWNRKPLPTVDDGKIKKVANAILCALGSLFSKPIKDLLGKLKPLNLLH
LLASCDWTFAGIVETVILMAELFNIFWTPPDVSNFIASLIGDFELQGPEDLAVELVPV
VMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMKWFFPKKEEKAEM
ETLRAIEDAVLDMEAIGNNHLTTLLKDKDSLTAFMKTLDLEEEKARKLSTKSSSPDIV
GTINAILARIAAARSLLHKAKEEMFSRIRPVVVMISGRPGIGKTHMARHLAKSIANTM
SGDQRVGLVPRNGVDHWDAYRGERVVLWDDYGMGSPVKDALTLQELADTCPVTLNCDR
IENKGKMFDSDVIIITTNLVNPAPLDYVNFEACSRRVDFLVYAESPEIEKVKRDFPGQ
PDMWKDHFKPDFSHIKLTLAPQGGFDKNGNTPHGKGTMRSLTQGSLTARVAGLVHERR
DEFQLQGNDLQTYNFDTNRVSAFRKLAADNKYGIMETMRVGAALKNVKTLEDLKFALR
DVKFNECEIIYKNSKYRVSSNGKGSVSVDKIEDNASQTANEVQSAILRLRQARARYYI
SCFQDLVYTLIQVAGASFVVNRISKRFCWERWVKPTETQEVNESEKEVAQGRWEIEPK
DTEPEGKKGKNKKGRGKKHTAFSSKGLSDEEYDEFKRIREERNGKYSIEEYLQDRDRY
YEEVAVARATEEDFCEEEEAKIRQRIFRPTKKQRKEERGVLGLVTGTDIRKRRPDDFQ
PKGNLWADDTRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSNLLITTTHVLPKGV
KELFGVEIKQIQVHKSGEFCRFRFPRPIRPDVTGLVLEEGAPEGTVCSILIKRPTGEM
IPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDCGCPYIYKRGNDIV
VAGVHTAAARGGNTVICATQGQDGEAVLEGNEDLGTYCGAPILGPGKAPKLSTKTKFW
RSSPDALPPGTYEPAYLGGKDPRVERGPSLQQVMRDQLRPFTEPRGKPPRPAVLEEAK
KTVMNVLEQTIDPAKPWSYSQACASLDKTTSSGSPHHVKKNDHWNGESFTGPLADQAS
KANLMYEQAKHVQPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGTMIRCARAFGGLM
DSMKASCIALPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDSTQQRSILSAAMEV
MVRFSAEPELAQVVAEDLLAPSQLDVGDFIISVQEGLPSGVPCTSQWNSIAHWILTLS
AMAEVSGLSPDVVQAHSCFSFYGDDEIVSTDINLDPMKLTQKLREYGLVPTRPDKTEG
PLVITEDLTGLTFLRRSIARDPAGWFGKLDQDSILRQLYWTRGPNHENPYESMVPHSQ
RATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEAMFRWMRFSDLSTW
EGDRNLAPEGVNEDGVE"
mat_peptide <1..968
/gene="ORF1"
/product="p48"
mat_peptide 969..2066
/gene="ORF1"
/product="NTPase"
mat_peptide 2067..2585
/gene="ORF1"
/product="p22"
mat_peptide 2586..2984
/gene="ORF1"
/product="VPg"
mat_peptide 2985..3527
/gene="ORF1"
/product="Pro"
mat_peptide 3528..5057
/gene="ORF1"
/product="RdRp"
gene 5041..6651
/gene="ORF2"
CDS 5041..6651
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ59353.1"
/translation="MKMASNDATPSDDGAAGLVPEINSEVMALEPVAGASIAAPVVGQ
QNIIDPWIRNNFVQAPAGEFTVSPRNSPGELLLDLELGPELNPYLAHLARMYNGHAGG
MEVQIVLAGNAFTAGKILFAAIPPSFPYENLSPAQLTMCPHVIVDVRQLEPVLLPMPD
IRNVFYHYNQNNSPKLRLVAMLYTPLRANNSGDDVFTVSCRVLTRPSPDFQFTFLVPP
TVESKTKNFTLPVLRVSEMTNSRFPVVLDQMYTSRNENIIVQPQNGRCTTDGELLGTT
ILQSVSICNFKGTMQAKLNEEPRYQLQLTNLDGSPIDPTDDMPAPLGTPDFQAMLYGV
ASQRSSTDNATRAHDAQIDTAGDTFAPKIGQVRFKSSSNDFDLHDPTKFTPIGVNVDD
QHPFRQWSLPNYGGHLALNNHLAPAVTPLFPGEQILFFRSYIPSAGGHTDGAMDCLLP
QEWVEHFYQEAAPSQSDIALVRFINPETGRVLFEAKLHKQGFLTIAASGDHPIVMPTN
GYFRFEAWVNPFYTLAPVGTGSGRRRIQ"
gene 6651..7445
/gene="ORF3"
CDS 6651..7445
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ59354.1"
/translation="MAGAFLAGLAGDVVTSSLGSLVGAGANAINQKVEYDFNRQLQEA
SFRHDKDMLKAQVAATAGLQQAMIDIKREALTAGGFSPADAARGAVRAPMTQILDWNG
SRYWAPNSMKTTGYSGTFASQGIKSSPHLSNQIPSAVKSTKPLPSISSSSSVYSSPST
APSQSTQSTTLSVGTGSSRSNTVSTKTSTLSRTSDWVRGQNEMLGPFMSGALQTAYVT
PPSSRASSQGTVSTVPKAVLDSWTPMFNTHRQPLFAHLRRRGESQI"
ORIGIN
1 cctttggcag tcaaaactct gtcaatgaca gtatcaacgc caccccttcc aataaggaag
61 aggttggtgc attctccaac atcaaagttg gatttaagaa aatgctgggt gctgtaccca
121 agagcaccag ggcacccagc agtggtcaac attgccccac agttaagatc gggcctaaaa
181 cattaacaat tccccctgag cccccaaatg aagacactgt gcagtttgat gcaaagtcgg
241 aaactataat cgggctgccg gacttgacaa cggtgcaaaa cgaacatgaa aacaccccat
301 acaccgtccc cccattaagt gagagggagc atagatcggc cactgaacca cttcctggca
361 caatattgga gatgtgggat ggtgaatttt accactactc cgtgtatgtc agcgatggca
421 aagctctggg ggtccacaaa ccaccggctg ctataagcct cgcgacgata gaactcaccc
481 ccatatctct ctactggaga cccgtttaca cccccaacta tttggtctcc ccagacacat
541 tgaaaggcct cgctggtgag aagttcccct acacggcctt cagtaacaat tgttataact
601 tttgttgttg ggtgcttgag ctcaacgaca cgtggctcaa tagaagatgc atttccagaa
661 ccaccggctt cttcaaaccc tatcagtcct ggaacaggaa gcccctccca accgtcgatg
721 atggaaagat caaaaaggtg gccaacgcga tcctctgtgc acttggctca ctgttctcaa
781 agccaattaa agatttgtta ggcaaactta agccattgaa cctgctacac ttgcttgcgt
841 catgcgattg gacgtttgca ggtatagtgg agacagtcat cttaatggca gaacttttca
901 atatcttctg gaccccgcca gatgtctcta attttatagc ctccctgata ggtgattttg
961 aattacaagg gcccgaggac ctggctgtgg aactcgttcc tgtggttatg ggtggcatag
1021 gaatggttct cggcttcacc gctgagaaga taggccgtat gctgtcatcc gccgcatcaa
1081 cactgcgggc atgcaaagac ctagggaact atgcccttga cattctcaaa ttggtcatga
1141 agtggttctt cccaaagaag gaggagaaag ctgagatgga aaccttaagg gcgatcgagg
1201 atgccgtcct agatatggaa gctataggga ataaccatct cacgaccctc ctcaaggaca
1261 aagacagcct cacggctttt atgaagaccc tggacttaga agaggaaaaa gctagaaaac
1321 tgtccactaa gtcatcttca ccggacatcg tcggcaccat taacgccata ctagctagga
1381 ttgctgctgc cagatccctt ctacataaag ccaaagaaga gatgtttagt aggatcagac
1441 cagtggtcgt tatgatatca ggcagacctg gcattggcaa aactcacatg gcaagacatt
1501 tggctaagag catcgccaac accatgagtg gcgaccagag agtcgggctc gtcccacgca
1561 acggtgtcga ccactgggat gcctacagag gagagagggt ggtcttgtgg gacgactacg
1621 gtatggggag ccctgttaaa gatgccttga cactacagga gctggccgac acctgcccag
1681 tcactttaaa ttgtgatagg attgagaaca aggggaagat gttcgacagt gatgtcatca
1741 taatcacaac caacctggtc aaccccgcgc ccctcgatta tgtgaacttc gaggcgtgtt
1801 ccaggagagt tgacttcttg gtctatgcag agtcaccaga gattgaaaag gtcaaaaggg
1861 acttccctgg ccaacctgac atgtggaagg accattttaa gccagacttt tctcacatca
1921 agctaacttt agccccccag ggcgggtttg acaagaatgg taacactcca cacggtaagg
1981 gtaccatgcg gtccctgacc caggggtccc tgactgcaag agttgcgggc cttgtccatg
2041 agaggagaga tgagttccaa ctccaaggaa acgatctcca aacatacaat tttgacacca
2101 acagagtttc cgcattcaga aaactggctg cagataacaa gtatggtatc atggaaacga
2161 tgagagtagg tgcggcactc aaaaatgtaa agaccttgga agatctaaaa tttgcattaa
2221 gggatgtaaa attcaatgag tgtgaaataa tttacaagaa ctctaagtat cgagtctctt
2281 ccaacggtaa aggctcagtt tctgttgaca aaattgagga caatgcatcc cagaccgcaa
2341 acgaggtaca atcagcaatt ctcaggctca ggcaagcgag ggccagatat tacatcagct
2401 gcttccaaga cctcgtctac actctcatac aggttgccgg agcatcattc gttgtcaaca
2461 gaatctccaa aaggttctgc tgggaaaggt gggtcaaacc aaccgagacc caggaagtga
2521 atgagtccga aaaggaagtg gctcaaggta gatgggaaat tgagcccaag gacacagaac
2581 cagaaggcaa gaaaggtaag aacaagaaag gaaggggcaa gaaacacaca gctttctcta
2641 gcaagggcct gagtgatgaa gagtatgacg agttcaagag aatcagggaa gaaaggaatg
2701 gaaagtactc cattgaggaa tacctgcaag accgggaccg ctattatgaa gaagtggcag
2761 ttgcccgggc aacagaggag gacttctgtg aggaggaaga ggccaaaata agacaaagaa
2821 ttttccgccc gacaaagaaa caaaggaagg aggaaagggg tgtacttggc ttagtcaccg
2881 gcacagacat cagaaagagg agaccagacg attttcaacc aaaaggcaat ctatgggcag
2941 atgacaccag gagtgtggac tacaatgaga gacttgattt tgaagcgccc ccaagtgtct
3001 ggtcaagaat agttccatta ggcactggtt ggggtttctg ggtttcatcc aaccttctaa
3061 tcacaacaac acacgtcctg cctaaagggg ttaaggaact ctttggagtt gaaattaaac
3121 agatccaagt tcacaagtct ggggagtttt gcaggttcag attcccaaga ccaatcaggc
3181 cagatgtcac agggctcgtg ctggaggaag gcgccccaga aggcactgtc tgttctatac
3241 tcataaaaag acccacaggt gagatgatcc ccttggcagt gaggatgggc acacacgcat
3301 ccatgaaaat acaaggcagg accgttggtg gccagatggg aatgcttcta acaggagcaa
3361 atgcaaagaa catggatctt ggcaccggcc ctggtgactg cggttgtccc tacatctaca
3421 aacgcggcaa cgacatagtt gtcgcgggtg tccacaccgc agcagcccga ggaggtaaca
3481 ctgtcatatg cgccactcaa gggcaagatg gggaagcagt ccttgaggga aatgaggacc
3541 tcggtaccta ctgtggcgct ccaattctgg gccctggtaa ggcgcctaaa ctcagcacga
3601 agaccaagtt ttggcgctca tcaccagatg ccttgccacc tggcacatat gaacctgcct
3661 acctgggagg aaaagacccc agagtggaaa gaggaccttc cctgcagcaa gtcatgagag
3721 accagttgag acccttcaca gaacccaggg gaaagccgcc tagacctgca gtcttagaag
3781 aagccaagaa gacagtgatg aatgttttag aacaaaccat tgaccctgca aaaccgtggt
3841 cctactcgca agcatgcgcc tcactggaca aaaccacttc tagtggtagc ccccatcatg
3901 taaagaaaaa tgaccactgg aatggggagt ccttcactgg tccccttgca gatcaggcat
3961 ccaaagccaa cctcatgtat gaacaggcca aacatgtgca gcccgtgtac acggccgcgc
4021 tcaaagatga gcttgttaag actgacaaga tctacaaaaa gataaagaag agactcctat
4081 ggggatcgga ccttggaaca atgatcaggt gcgccagggc ttttggtggt ctcatggaca
4141 gcatgaaggc aagctgtata gctcttccat gcagggtagg aatgaacatg aatgaagatg
4201 gccctatcat atttgacaaa cattctaagt ataggtacca ctatgatgct gactattcta
4261 ggtgggactc aacccagcaa aggagcattc tttctgccgc tatggaagtg atggtgcgat
4321 tttctgctga accagaattg gcacaagtgg ttgcagagga ccttttagcg cctagtcagc
4381 ttgatgttgg tgattttatc atctcagttc aggagggcct gccatcagga gtcccatgca
4441 catcacaatg gaactcaata gcacactgga tcctaacttt gagtgcgatg gcagaagtgt
4501 caggtctctc accagatgtt gtccaagctc attcctgctt ttcattttat ggggacgatg
4561 agatcgtcag cactgatatc aaccttgacc ccatgaagtt gacacagaaa ctcagggagt
4621 acggcctggt tcccacccga cctgataaaa ctgaaggtcc cctcgtcata actgaagacc
4681 tcaccggcct gacgttcctt cgtaggtcga ttgcacggga cccagctgga tggtttggaa
4741 aattggacca agattcaatc ctcaggcaac tatactggac aagggggcct aaccatgaga
4801 acccgtacga gagcatggtc cctcattctc agcgggccac acagcttatg gcccttcttg
4861 gcgaggcttc actgcatggc ccccaatttt acaagaaagt cagcaaaatg gttatcaatg
4921 agattaagag tggtggtctg gaattttatg tgcccagaca ggaggccatg tttaggtgga
4981 tgagattctc tgacctcagc acatgggagg gcgatcgcaa tcttgctccc gaaggtgtga
5041 atgaagatgg cgtcgaatga cgctactcca tctgatgatg gtgcagccgg cctcgtacca
5101 gagatcaaca gtgaggttat ggctcttgaa cccgtcgctg gggcctccat tgcagccccc
5161 gtagtcggcc aacagaatat aattgatccc tggattagaa ataattttgt acaagcccct
5221 gctggtgaat tcacagtttc ccctagaaac tctcctggag aacttctact tgatttggaa
5281 ttgggtcctg aacttaatcc ctatcttgca catttggcca ggatgtacaa tgggcatgca
5341 ggaggaatgg aagtgcagat agtactggct gggaatgcgt tcacagctgg taaaatccta
5401 tttgctgcca tcccgcctag cttcccctat gaaaatttgt cacccgctca attgactatg
5461 tgcccccatg tgatagtgga tgtgagacaa ttggaaccag tgcttctgcc aatgccagat
5521 ataagaaatg ttttctatca ctataaccag aacaatagtc ccaaacttag gcttgtagct
5581 atgctttata ctcctctgag ggccaacaac tcaggtgatg acgtgttcac ggtctcttgc
5641 cgcgttttaa cacgcccttc tccagatttc cagttcacct ttctggtccc tcctacagtt
5701 gagtctaaaa ctaagaattt cacccttccc gttctcagag tctcagagat gacaaattca
5761 aggttccccg ttgtcttgga ccaaatgtat acaagcagga atgaaaacat cattgtccag
5821 ccccaaaacg gcaggtgcac gactgacggt gagctgcttg gcactaccat cttgcagtct
5881 gtgtctattt gcaattttaa aggaacaatg caggcaaagc tgaatgaaga accacgatac
5941 cagttacagc tcaccaactt ggatggatca cccatagatc caacagatga tatgcctgcc
6001 cctcttggca caccagattt ccaggccatg ttatatggcg ttgcaagtca acgctcttcc
6061 acagacaatg ccaccagggc acatgatgca cagattgaca ctgcgggtga cacattcgcc
6121 ccgaaaattg gccaggttcg ttttaaatca agctctaatg attttgacct acatgaccct
6181 acaaaattca cacctattgg tgtcaatgtg gatgatcagc accctttcag acagtggtcc
6241 ctaccaaact acggtggtca ccttgccctg aacaatcact tagcccccgc tgtgacacca
6301 ctctttcctg gcgagcagat tttgttcttc aggtcataca ttccaagcgc cggaggccac
6361 acagacggtg ctatggactg cttgctgccc caagagtggg tagagcactt ctaccaggaa
6421 gctgcccctt cccaatctga catcgcactg gtaaggttca tcaaccctga aacaggaaga
6481 gtgctctttg aagctaaatt gcataaacaa ggtttcctca caattgcagc atctggagat
6541 caccctattg tgatgcccac taatggttac tttaggtttg aagcttgggt caaccctttc
6601 tatactctcg cccccgtggg aactgggtct gggcgcagga ggattcaata atggctggag
6661 ctttccttgc aggtttggca ggtgacgttg tgacttccag cttgggctca cttgtgggcg
6721 ctggagccaa cgccatcaac cagaaagtgg agtatgactt caacagacag ctccaggagg
6781 catcttttag acatgataag gatatgctca aagcccaggt tgcagcaaca gcaggccttc
6841 aacaggccat gatagacatc aagcgggagg cattgaccgc aggcggcttt tcccccgctg
6901 atgctgcaag aggtgcagtt agagcgccta tgacacagat tcttgactgg aatggttcta
6961 ggtattgggc ccccaactcc atgaagacaa ctggctattc aggtacattt gcctcccaag
7021 gcattaaaag ttccccccac ctgtctaatc aaattccaag tgctgttaaa tctaccaaac
7081 ctttaccatc tatatctagt tcttctagtg tatatagttc tccttctact gccccttcac
7141 aatcaacaca atcaacaacg ctgtctgtag gaacagggtc ctccagatct aacaccgtgt
7201 ccacaaagac ctctacactg tcgaggacga gtgactgggt cagaggtcaa aatgagatgc
7261 ttggcccgtt catgagtggt gcactccaaa ctgcttatgt cacaccacca tcaagcaggg
7321 cctcatcaca aggtacggtc tcgaccgtgc ccaaggctgt tttggactcc tggactccca
7381 tgttcaacac ccacaggcag cctctcttcg cccacttgcg taggcgaggg gagtcacaga
7441 tttagtgaaa aggatgatta gggtttcttc ctttcccctt cttattcttt
//