Typing tool
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Typing tool
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Complete norovirus genomes
| MW305666 | GII.14 | |
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| GII.P7 |
ORF1: 1..5063
ORF2: 5044..6654
ORF3: 6654..7448
LOCUS MW305666 7493 bp RNA linear VRL 06-JUL-2021
DEFINITION Norovirus GII isolate 10609 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MW305666
VERSION MW305666.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7493)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses reveal coexistence of
viral populations evolving under recombination constraints
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7493)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7493
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="10609"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Japan"
/collection_date="25-Jan-2011"
/note="genotype: GII.14[GII.P7]"
gene <1..5063
/gene="ORF1"
CDS <1..5063
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QPJ59334.1"
/translation="FGSQNSVNDSINATPSNKEEVGAFSNIKVGFKKMLGAVPKSTRA
PSSGQHCPTVKIGPKTLTIPPEPPNGEDTVQFDAKSETIIGLPDLTTVQNEHENTPYT
VPPLSEREHRSATEPLPGTILEMWDGEFYHYSVYVSDGKALGVHKPPAAISFATIELT
PISLYWRPVYTPNYLVSPDTLKGLAGEKFPYTAFSNNCYNFCCWVLELNDTWLNRRCI
SRTTGFFKPYQSWNRKPLPTVDDGKIKKVANAILCALGSLFSKPIKDLLGKLKPLNLL
HLLASCDWTFAGIVETVILMAELFNIFWTPPDVSNFIASLIGDFELQGPEDLAVELVP
VVMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMKWFFPKKEEKAE
METLRAIEDAVLDMEAIGNNHLTTLLKDKDSLTAFMKTLDLEEEKARKLSTKSSSPDI
VGTINAILARIAAARSLLHKAKEEMFSRIRPVVVMISGRPGIGKTHMARHLAKSIANT
MSGDQRVGLVPRNGVDHWDAYRGERVVLWDDYGMGSPVKDALTLQELADTCPVTLNCD
RIENKGKMFDSDVIIITTNLVNPAPLDYVNFEACSRRVDFLVYAESPEIEKVKRDFPG
QPDMWKDHFKPDFSHIKLTLAPQGGFDKNGNTPHGKGTMRSLTQGSLTARVAGLVHER
RDEFQLQGNDLQTYNFDTNRVSAFRKLAADNKYGIMETMRVGAALKNVKTLEDLKLAL
RDVKFNECEIIYKNSKYRVSSNGKGSVSVDKIEDNASQTANEVQSAILRLRQARARYY
ISCFQDLVYTLIQVAGASFVVNRISKRFCWERWVKPTETQEVNESEKEVAQGRWEIEP
KDTEPEGKKGKNKKGRGKKHTAFSSKGLSDEEYDEFKRIREERNGKYSIEEYLQDRDR
YYEEVAVARATEEDFCEEEEAKIRQRIFRPTKKQRKEERGVLGLVTGTDIRKRRPDDF
QPKGNLWADDTRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSNLLITTTHVLPKG
VKELFGVEIKQIQVHKSGEFCRFRFPRPIRPDVTGLVLEEGAPEGTVCSILIKRPTGE
MIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDCGCPYIYKRGNDI
VVAGVHTAAARGGNTVICATQGQDGEAVLEGNEDLGTYCGAPILGPGKAPKLSTKTKF
WRSSPDALPPGTYEPAYLGGKDPRVERGPSLQQVMRDQLRPFTEPRGKPPRPAVLEEA
KKTVMNVLEQTIDPAKPWSYSQACASLDKTTSSGSPHHVKKNDHWNGESFTGPLADQA
SKANLMYEQAKHVQPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGTMIRCARAFGGL
MDSMKASCIALPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDSTQQRSILSAAME
VMVRFSAEPELAQVVAEDLLAPSQLDVGDFIISVQEGLPSGVPCTSQWNSIAHWILTL
SAMAEVSGLSPDVVQAHSCFSFYGDDEIVSTDINLDPMKLTQKLREYGLVPTRPDKTE
GPLVITEDLTGLTFLRRSIARDPAGWFGKLDQDSILRQLYWTRGPNHENPYESMVPHS
QRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEAMFRWMRFSDLST
WEGDRNLAPEGVNEDGVE"
mat_peptide <1..971
/gene="ORF1"
/product="p48"
mat_peptide 972..2069
/gene="ORF1"
/product="NTPase"
mat_peptide 2070..2588
/gene="ORF1"
/product="p22"
mat_peptide 2589..2987
/gene="ORF1"
/product="VPg"
mat_peptide 2988..3530
/gene="ORF1"
/product="Pro"
mat_peptide 3531..5060
/gene="ORF1"
/product="RdRp"
gene 5044..6654
/gene="ORF2"
CDS 5044..6654
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ59335.1"
/translation="MKMASNDATPSDDGAAGLVPEINSEVMALEPVAGASIAAPVVGQ
QNIIDPWIRNNFVQAPAGEFTVSPRNSPGELLLDLELGPELNPYLAHLARMYNGHAGG
VEVQIVLAGNAFTAGKILFAAIPPSFPYENLSPAQLTMCPHVIVDVRQLEPVLLPMPD
IRNVFYHYNQNNSPKLRLVAMLYTPLRANNSGDDVFTVSCRVLTRPSPDFQFTFLVPP
TVESKTKNFTLPVLRVSEMTNSRFPVVLDQMYTSRNENVIVQPQNGRCTTDGELLGTT
ILQSVSICNFKGTMQAKLNEEPRYQLQLTNLDGSPIDPTDDMPAPLGTPDFQAMLYGV
ASQRSSTDNATRAHDAQIDTAGDTFAPKIGQVRFKSSSNDFDLHDPTKFTPIGVNVDD
QHPFRQWSLPNYGGHLALNNHLAPAVTPLFPGEQILFFRSYIPSAGGHTDGAMDCLLP
QEWVEHFYQEAAPSQSDIALVRFINPETGRVLFEAKLHKQGFLTIAASGDHPIVMPTN
GYFRFEAWVNPFYTLAPVGTGSGRRRIQ"
gene 6654..7448
/gene="ORF3"
CDS 6654..7448
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ59336.1"
/translation="MAGAFLAGLAGDVVTSSLGSLVGAGANAINQKVEYDFNRQLQEA
SFRHDKDMLKAQVAATAGLQQAMIDIKREALTAGGFSPADAARGAVRAPMTQILDWNG
SRYWAPNSMKTTGYSGTFASQGIKSSPHLSNQIPSAVKSTKPLPSISSSSSVYSSPST
APSQSTQSTTLSVGTGSSRSNTVSTKTSTLSRTSDWVRGQNEMLGPFMSGALQTVYVT
PPSSRASSQGTVSTVPKAVLDSWTPMFNTHRQPLFAHLRRRGESQI"
ORIGIN
1 cctttggcag tcaaaactct gtcaatgaca gtatcaacgc caccccttcc aataaggaag
61 aggttggtgc attctccaac atcaaagttg gatttaagaa aatgctgggt gctgtaccca
121 agagcaccag ggcacccagc agtggtcaac attgccccac agttaagatc gggcctaaaa
181 cattaacaat tccccctgag cccccaaatg gtgaagacac tgtgcagttt gatgcaaagt
241 cggaaactat aatcgggctg ccggacttga caacggtgca aaacgaacat gaaaacaccc
301 catacaccgt ccccccacta agtgagaggg agcatagatc ggccactgaa ccacttcctg
361 gcacaatatt ggagatgtgg gatggtgaat tttaccacta ctccgtgtat gtcagcgatg
421 gcaaagctct gggggtccac aaaccaccgg ctgctataag cttcgcgacg atagaactca
481 cccccatatc tctctactgg agacccgttt acacccccaa ctatttggtc tccccagaca
541 cattgaaagg cctcgctggt gagaagttcc cctacacggc cttcagtaac aattgttata
601 acttttgttg ttgggtactt gagctcaacg acacgtggct caatagaaga tgcatttcca
661 gaaccaccgg cttcttcaaa ccctatcagt cctggaacag gaaacccctc ccaaccgttg
721 atgatggaaa gatcaaaaag gtggccaacg cgatcctctg tgcacttggc tcactgttct
781 caaagccaat caaagatttg ttaggcaaac ttaaaccatt gaacctgcta cacttgcttg
841 cgtcatgcga ttggacgttt gcaggtatag tggagacagt catcttaatg gcagaacttt
901 tcaatatctt ctggaccccg ccagatgttt ctaattttat agcctccctg ataggtgatt
961 ttgaattaca agggcccgag gacctggctg tggaactcgt tcctgtggtt atgggtggca
1021 taggaatggt tctcggcttc accgctgaga agataggccg tatgctgtca tccgccgcat
1081 caacactgcg ggcatgcaaa gacctgggga actatgccct tgacattctc aaattggtca
1141 tgaagtggtt cttccccaag aaggaagaga aagctgagat ggaaacctta agggcgatcg
1201 aggatgccgt cctagatatg gaagctatag ggaataacca tctcacgacc ctcctcaagg
1261 acaaagacag cctcacggct tttatgaaga ccttggactt agaagaggaa aaagctagaa
1321 aactgtccac taagtcatct tcaccggaca tcgtcggcac cattaacgcc atactagcta
1381 ggattgctgc tgccagatcc cttctgcata aagccaaaga agagatgttt agtaggatca
1441 gaccagtggt cgttatgata tcaggcagac ctggcattgg caaaactcac atggcaagac
1501 atttggctaa gagcatcgcc aacaccatga gtggcgacca gagagtcggg ctcgtcccac
1561 gcaacggtgt cgaccactgg gatgcctata gaggagagag ggtggtcttg tgggacgact
1621 acggtatggg gagccctgta aaagatgcct tgacactaca ggagctggcc gacacctgcc
1681 cagtcacttt aaattgtgat aggattgaga acaaggggaa gatgttcgac agtgatgtca
1741 tcataatcac aaccaacctg gtcaaccccg cgcccctcga ttatgtgaac ttcgaggcgt
1801 gttccaggag agttgacttc ttggtctatg cagagtcacc agagattgaa aaggttaaaa
1861 gggacttccc tggccaacct gacatgtgga aggaccattt taagccagac ttttctcaca
1921 tcaagctaac tttagccccc cagggcgggt ttgacaagaa tggtaacact ccacacggca
1981 agggcaccat gcggtccctg acccaggggt ccctgactgc aagagttgcg ggccttgtcc
2041 atgagaggag agatgagttc caactccaag gaaacgacct ccaaacatac aattttgaca
2101 ccaacagagt ctccgcattc agaaaactgg ctgcagataa caagtatggt atcatggaaa
2161 cgatgagagt aggtgcggca ctcaaaaatg taaagacctt ggaagatcta aaacttgcat
2221 taagggatgt aaaattcaat gagtgtgaaa taatttacaa gaactctaag tatcgagtct
2281 cttccaacgg taaaggctca gtttctgttg acaaaattga ggacaatgca tcccagaccg
2341 caaacgaggt acaatcagca attctcaggc tcaggcaagc gagggccaga tattacatca
2401 gctgcttcca agacctcgtt tacactctca tacaggttgc cggagcgtca ttcgttgtca
2461 acagaatctc caaaaggttc tgctgggaaa ggtgggtcaa accaaccgag acccaggaag
2521 tgaatgagtc cgaaaaggaa gtggctcaag gtagatggga aattgagccc aaggacacag
2581 aaccagaagg caagaaaggt aagaacaaga aaggaagggg caagaaacac acagcttttt
2641 ctagcaaagg cctgagtgat gaagagtatg acgagttcaa gagaatcagg gaagaaagga
2701 atggaaagta ctccattgag gaatacctgc aagaccggga ccgctattat gaagaagtgg
2761 cagttgcccg ggcaacagag gaggacttct gtgaggagga ggaggccaaa ataagacaaa
2821 gaattttccg cccgacaaag aaacaaagga aggaggaaag gggtgtactt ggcttagtca
2881 ccggcacaga catcagaaag aggagaccag acgattttca accaaaaggc aatctatggg
2941 cagatgacac caggagtgtg gactacaatg agagacttga ttttgaagcg cccccgagtg
3001 tctggtcaag aatagtccca ttgggcactg gttggggttt ctgggtttca tccaaccttc
3061 taatcacaac aacacacgtc ctgcctaaag gggttaagga actctttgga gttgaaatca
3121 aacagatcca agttcacaag tctggggagt tttgcaggtt cagattccca agaccaatca
3181 gaccagatgt cacagggctc gtgttggagg aaggcgcccc agaaggcact gtctgctcta
3241 tactcataaa aagacccaca ggtgagatga tccccttggc agtgaggatg ggcacacacg
3301 catccatgaa aatacaaggc aggaccgttg gtggccagat gggaatgctt ctaacaggag
3361 caaatgcaaa gaacatggat cttggcaccg gccctggtga ctgcggttgt ccctacatct
3421 acaaacgcgg caacgacata gttgtcgcgg gtgtccacac cgcagcagcc cgaggaggta
3481 acaccgtcat atgcgccact caagggcaag atggggaagc agtccttgag ggaaatgagg
3541 acctcggtac ctactgtggc gctccaattc taggccctgg taaggcgcct aaactcagca
3601 cgaagaccaa gttttggcgc tcatcaccag atgccttgcc acctggcaca tatgaacctg
3661 cttacctggg agggaaagac cccagagtgg aaagaggacc ttccctgcag caagtcatga
3721 gagaccagtt gagacccttc acagaaccca ggggaaagcc gcctagacct gcagtcttag
3781 aagaagccaa gaagacagtg atgaatgttt tagaacaaac cattgaccct gcaaaaccgt
3841 ggtcctactc gcaagcatgc gcctcactgg acaaaaccac ttctagtggt agcccccatc
3901 atgtaaagaa aaatgaccac tggaatgggg agtccttcac tggtcccctt gcagatcagg
3961 catccaaagc caatctcatg tatgaacagg ccaaacatgt gcagcccgtg tacacggccg
4021 cgctcaaaga tgagcttgtt aagactgaca agatctacaa aaagataaag aagagactcc
4081 tatggggatc ggaccttgga acaatgatca ggtgcgccag ggcttttggt ggtctcatgg
4141 acagcatgaa ggcaagctgt atagctcttc catgcagggt aggaatgaac atgaatgaag
4201 atggccctat catatttgac aaacattcta agtataggta ccactatgat gctgactatt
4261 ctaggtggga ctcaacccag caaaggagca ttctttctgc cgctatggaa gtgatggtgc
4321 gattttctgc tgaaccagaa ttggcacaag tggttgcaga ggaccttttg gcgcctagtc
4381 agcttgatgt tggtgatttt atcatctcag ttcaggaggg cctgccatca ggagtcccat
4441 gtacatcaca atggaactca atagcacact ggatcctaac tttgagtgcg atggcagaag
4501 tgtcaggtct ctcaccagat gttgtccaag ctcactcctg cttttcattt tatggggacg
4561 atgagatcgt cagcactgat atcaaccttg accccatgaa gttgacacag aaactcaggg
4621 agtacggcct ggttcccacc cgacctgata aaactgaagg tcccctcgtc ataactgaag
4681 acctcaccgg cctgacgttc cttcgtaggt cgattgcacg ggacccagct ggatggtttg
4741 ggaaattgga ccaagattca atcctcaggc aactatactg gacaaggggg cctaaccatg
4801 agaacccgta cgagagcatg gtccctcatt ctcagcgggc cacacagctt atggcccttc
4861 ttggcgaggc ttcactgcat ggtccccaat tttacaagaa agtcagcaaa atggttatca
4921 atgagattaa gagtggtggt ctggaatttt atgtgcccag acaggaggcc atgtttaggt
4981 ggatgagatt ctctgacctc agcacatggg agggcgatcg caatcttgct cccgaaggtg
5041 tgaatgaaga tggcgtcgaa tgacgctact ccatctgatg atggtgcagc cggcctcgta
5101 ccagagatca acagtgaggt tatggctctt gaacccgtcg ctggggcctc cattgcagcc
5161 cccgtagtcg gccaacagaa tataattgat ccctggatta gaaataattt tgtacaagcc
5221 cctgctggtg aattcacagt ttcccctaga aactctcctg gagaacttct acttgatttg
5281 gaattgggtc ctgaacttaa tccctatctt gcacatttgg ccaggatgta caatgggcat
5341 gcaggaggag tggaagtgca gatagtactg gctgggaatg cgttcacagc tggtaaaatc
5401 ctatttgctg ccatcccgcc tagcttcccc tatgaaaatt tgtcacccgc tcaattgact
5461 atgtgccccc atgtgatagt ggatgtgaga caattggaac cagtgctcct gccaatgcca
5521 gatataagaa atgttttcta tcactataac cagaacaata gtcccaaact taggcttgta
5581 gctatgcttt atactcctct gagggctaac aactcaggtg atgacgtgtt cacggtctct
5641 tgccgcgttt taacacgccc ttctccagat ttccagttca cctttctggt ccctcctaca
5701 gttgagtcta aaactaagaa tttcaccctt cccgttctca gagtctcaga gatgacaaac
5761 tcaaggttcc ccgttgtctt ggaccaaatg tatacaagca ggaatgaaaa cgtcattgtc
5821 cagccccaaa acggcaggtg cacgactgac ggtgagctgc ttggcactac catcttgcag
5881 tctgtgtcta tctgcaattt taaaggaaca atgcaggcaa agctgaatga agaaccacga
5941 taccagttac aactcaccaa cttggatgga tcacccatag atccaacaga tgatatgcct
6001 gcccctcttg gcacaccaga tttccaggcc atgttatatg gcgttgcaag tcaacgctct
6061 tccacagaca atgccaccag ggcacatgat gcacagattg acactgcggg tgacacattc
6121 gccccgaaaa ttggccaggt tcgttttaaa tcaagctcta atgattttga cctacatgac
6181 cctacaaaat tcacacctat tggtgtcaat gtggatgatc agcacccttt cagacagtgg
6241 tccctaccaa actacggtgg tcaccttgcc ctgaacaatc acttagcccc cgctgtgaca
6301 ccactctttc ctggcgagca gattttgttc ttcaggtcat acattccaag cgccggaggc
6361 cacacagacg gtgctatgga ctgcttgctg ccccaagagt gggtagagca cttctaccag
6421 gaagctgccc cttcccaatc tgacatcgca ctggtaaggt tcatcaaccc tgaaacagga
6481 agagtgctct ttgaagctaa attgcataaa caaggttttc tcacaattgc agcatctgga
6541 gatcacccta ttgtgatgcc cactaatggt tactttaggt ttgaagcttg ggtcaaccct
6601 ttctatactc tcgcccccgt gggaactggg tctgggcgca ggaggattca ataatggctg
6661 gagctttcct tgcaggtttg gcaggtgacg ttgtgacttc cagcctgggc tcacttgtgg
6721 gcgctggagc caacgccatc aaccagaaag tggagtatga cttcaacaga cagctccagg
6781 aggcatcttt cagacatgat aaggatatgc tcaaagccca ggttgcagca acagcaggcc
6841 ttcaacaggc catgatagac atcaagcggg aggcattgac cgcaggcggc ttttcccccg
6901 ctgatgctgc aagaggtgca gttagagcgc ctatgacaca gattcttgac tggaatggtt
6961 ctaggtattg ggcccccaac tccatgaaga caactggcta ttcaggtaca tttgcctccc
7021 aaggcattaa aagttccccc cacctgtcta atcaaattcc aagtgctgtt aaatctacca
7081 aacctttacc atctatatct agttcttcta gtgtatatag ttctccttct actgcccctt
7141 cacaatcaac acaatcaaca acgctgtctg taggaacagg gtcctccaga tctaacaccg
7201 tgtccacaaa gacctctaca ctgtcgagga cgagtgactg ggtcagaggt caaaatgaga
7261 tgcttggccc gttcatgagt ggtgcactcc aaactgttta tgtcacacca ccatcaagca
7321 gggcctcatc acaaggtacg gtctcgaccg tacctaaggc tgttttggac tcctggactc
7381 ccatgttcaa cacccacagg cagcctctct tcgcccactt gcgtaggcga ggggagtcac
7441 agatttagtg aaaaggatga ttagggtttc ttcctttccc cttcttattc ttt
//