Typing tool
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Typing tool
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Complete norovirus genomes
| MW305658 | GII.5 | |
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| GII.P5 |
ORF1: 1..5063
ORF2: 5044..6666
ORF3: 6666..7442
LOCUS MW305658 7477 bp RNA linear VRL 06-JUL-2021
DEFINITION Norovirus GII isolate 1034 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MW305658
VERSION MW305658.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7477)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses reveal coexistence of
viral populations evolving under recombination constraints
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7477)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7477
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="1034"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Japan"
/collection_date="28-Feb-1997"
/note="genotype: GII.5[GII.P5]"
gene <1..5063
/gene="ORF1"
CDS <1..5063
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QPJ59310.1"
/translation="VACNNNNDKEKSSGEGLFTNMSSTLKKALGARPKQPVPRDNSQK
PPRPPTPELIKRMPPPPPNGEDEPTVRYEVTKGVSGLPELTTVTQPDSTNTAFSVPPL
SLRENKEAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAISMAKVEMTPLSL
YWRVVYTPQYLISPDTLKRLDGEAFPYTAFDNNCYAFCCWVLDLNDSWLSRRMVQRTT
GFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDIIGKIRPLNILNILA
TCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDIAVELVPVVMG
GIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKEEASELAMV
RAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKSASPDIVGTI
NALLARIAAARSLVHRAKEELSSRIRPVVVMMSGRPGIGKTHLAREVAKKVASTLTGD
QRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCPLTLNCDRIEN
KGKVFDSDVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAKRDFPGQPDM
WKDAFKSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGLLHERMDEF
ELQGPAITTFNFDRNKIAAFRQLAAENKYGIMDTMRIGNQLKGVKTMEELKQAIKNVS
IKRCQIIYNGSTFSLESDGKGKVLVEKIKSATIQTSNELAGALRHLRSARIRYYVKCV
QEAIYSILQIAGAAFVTTRIARRMNIQELWAKPPIDQDESEPREENPKLEDDEFIISS
KDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRDR
YYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVTGSEIRRRNPDDF
KPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPSLFITSTHVIPSG
ITEVFGVPVKQVQIHKSGEFCRFRFPKPIRTDVTGMILEEGAPEGTVATILIKRPTGE
LMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDCGCPYIYKRGNDY
IVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGPGGAPKLSTKTKF
WRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPRGKPPKPSVLEAA
KQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHTRKNEFWNGETFTGKLADQA
SKANLMFEEGKHMTPVYTAALKDELVKTDKIYGKIKKRLLWGSDLSTMVRCARAFGGL
MEEMKAHCISLPIRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDSTQQRDVLAAAME
IMVRFSAEPQLSQKVAEDLLAPSVVDVGDFKISINEGLPSGVPCTSQWNSITHWLLTL
CALSETTNLSPDIIQANSMFSFYGDDEIVSTDIKLDPEKLTTKLREYGLKPTRPDKTE
GPLIISEDLDGLTFLRRTVSRDPAGWFGKLDQSSILRQMYWTRGPNHEDPNETMIPHS
QRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQEPMFRWMRFSDLST
WEGDRNLAPSFVNEDGVE"
mat_peptide <1..959
/gene="ORF1"
/product="p48"
mat_peptide 960..2057
/gene="ORF1"
/product="NTPase"
mat_peptide 2058..2588
/gene="ORF1"
/product="p22"
mat_peptide 2589..2987
/gene="ORF1"
/product="VPg"
mat_peptide 2988..3530
/gene="ORF1"
/product="Pro"
mat_peptide 3531..5060
/gene="ORF1"
/product="RdRp"
gene 5044..6666
/gene="ORF2"
CDS 5044..6666
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ59311.1"
/translation="MKMASNDATPSNDGAAGLVPESNNEAMALEPVVGASLAAPVTGQ
TNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILVNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKIIFAAVPPYFPVENLSPSQITMFPHVIIDVRTLEPVLLPMPD
VRSTLFHFNQKDEPKMRLVAMLYTPLRSNGSGDDVFTVSCRILTRPSPEFDFTYLVPP
TVESKTKPFTLPVLTLGELSNSRFPLSIDEMVTSPNESIVVQPQNGRVTLDGELLGTT
QLQACNICSIRGKVTGQVPNEQHMWNLEITNLNGTQFDPTDDVPAPLGVPDFAGEVFG
VLSQRNRGESNPANRAHDAVVATYSDKYTPKLGLVQIGTWNTNDVENQPTKFTPIGLN
EVANGHRFEQWTLPRYSGALTLNMNLAPAVAPLFPGERLLFFRSYVPLKGGFGNPAID
CLVPQEWVQHFYQESAPSLGDVALVRYVNPDTGRVLFEAKLHKGGFLTVSSTSTGPVV
VPANGYFRFDSWVNQFYSLAPMGTGNGRRRFQ"
gene 6666..7442
/gene="ORF3"
CDS 6666..7442
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ59312.1"
/translation="MAGAFIAGLAGDVLSNGLGSLINAGANAINQRAEFDFNRQLQQN
SFNHDKEMLNAQIQATKQLQADMIAIKQGVLAAGGFSPTDAARGAVNAPMTQALDWSG
TRYWAPGSMKTTSYSGKFVSMNPVRQVEFPQPKKSAAIPSSASSVSSGRTNLTNSTQS
TVVSTSSVPPSRGSSAPSTLSRATTRTSNWVEEQNRNLEPYMRGALQTTFVTPPSSRA
SSNGTVSTVPKGVLDSWTPAFNTRRQPLFAYLRKKGESQV"
ORIGIN
1 ccgttgcttg caacaacaac aacgacaagg aaaaatcttc gggtgaaggc ctgtttacaa
61 acatgtcttc taccctaaag aaagccctcg gggcacggcc taaacagcct gtcccgaggg
121 acaactcaca aaaaccacca aggccaccca cgcctgagct gattaaaagg atgccccccc
181 ccccgcctaa cggtgaagac gagccaaccg ttaggtacga agtcacaaaa ggggtatccg
241 gcctacctga gctcacgaca gttacacaac cagattcaac caacacggca tttagtgtcc
301 caccgttgag tctgagagag aacaaggagg ctaaggagcc gctgaccggg gcaatactgg
361 aaatgtggga tggagagata taccactatg gtttgtatgt ggagaaaggt cttgtgctgg
421 gtgtgcacaa accacccgca gccataagca tggcgaaggt ggaaatgaca ccgctttcgt
481 tatactggcg tgtggtgtac accccccagt atctcatttc ccctgacacg ctcaagagac
541 tcgatggaga ggcgttccca tacaccgctt ttgacaacaa ctgttacgcc ttttgctgct
601 gggtgctaga tcttaatgat tcatggctta gtaggagaat ggtgcaaaga acaacaggct
661 tcttcaggcc ctaccaggag tggaacagga aacctctgcc caccatggat gactccaaga
721 tcaagaaagt ggcgaacata tttttatgct ctttatctac actattcact aggcccatta
781 aagacattat tggaaaaatt agaccattaa atattttaaa cattctggca acatgtgatt
841 ggacgttcgc tgggatcgtg gagtcgctaa tcttgcttgc tgagctcttt ggagtgttct
901 ggacaccccc agatgtgtct gcaatgattg cccccctact tggtgactac gagttacaag
961 gacctgagga catcgctgtc gaactcgtac ccgtggtgat gggaggaatc ggtttggtgt
1021 taggctttac caaagagaag ataggcaaga tgctgtcttc agcagcatca acactcagag
1081 cctgtaaaga ccttggggcc tatggattgg aaatactcaa gctggttatg aaatggttct
1141 tccccaagaa agaagaagct agtgagctag ccatggtgag ggctatagag gatgccgtgt
1201 tggaccttga ggcaatagaa aacaatcaca tgacgacact gctcaaagac aaagacagcc
1261 tcgcaaccta catgagaaca ctagaccttg aggaagaaaa agccaggaag ttgtccacca
1321 agtctgcatc ccctgacata gttgggacaa ttaatgccct gttagcccga atagcggcag
1381 ccaggtcact ggttcacagg gccaaggagg aactgtctag tagaatcagg ccagttgttg
1441 ttatgatgtc tggtagacca ggtataggga agacacacct ggccagggaa gtggcgaaga
1501 aggtggcatc caccctcaca ggggaccaga gggttggact cataccaagg aatggtgtag
1561 accattggga tgcatacaag ggcgaaaggg tcgtgctatg ggacgactat ggcatgagta
1621 accccattca tgatgccctg cgcctgcagg agctggccga cacatgcccc ttaacattaa
1681 attgtgatag aattgagaat aaagggaagg tgtttgatag tgatgttata atcattacaa
1741 cgaaccttgc aaatccagcc cctcttgatt atgtcaactt tgaggcttgc tccaggcgca
1801 ttgacttcct ggtttatgcc gaagcaccgg aagtggaaaa ggcaaagcga gacttccccg
1861 gtcagccaga catgtggaaa gatgctttta aatcagactt ctcacatatt aaactacaac
1921 ttgcacccca gggaggcttt gacaaaaatg ggaacacccc acatggaaaa ggtgtgatga
1981 aaacactcac cactggctct ctgatcgcta gggcgtcagg ccttctacac gagagaatgg
2041 acgagttcga actccagggc ccagcaatca ccactttcaa cttcgaccgt aacaaaattg
2101 ccgcgttcag acagttggct gcggaaaaca aatatggaat aatggacacc atgcggattg
2161 gcaaccaact gaaaggggtg aaaactatgg aggaacttaa acaggcaatc aagaacgtgt
2221 ccatcaaaag gtgtcaaata atttacaatg gctctacatt cagtctcgag tctgatggca
2281 aaggcaaggt tttggtggag aagatcaaaa gtgccactat tcaaaccagt aatgaactgg
2341 ccggggctct gcgccacctc agaagtgcca gaataaggta ttatgtgaaa tgtgtgcaag
2401 aagctatcta ctctattctt cagattgctg gtgccgcatt cgtcaccacg cgcattgcac
2461 gccgcatgaa catacaagaa ctctgggcaa aaccaccaat agaccaggat gaatcagagc
2521 ctagagaaga gaaccctaag ttggaggacg atgaattcat catatcatct aaagacatca
2581 aggaagaagg caagaagggc aagaacaaaa ctggccgtgg caagaaacac accgcattct
2641 ctagcaaggg cctaagtgat gaggagtatg atgagtacaa gaggataaga gaggaaagaa
2701 atggtaagta ctctattgaa gaatacctcc aggacagaga cagatactac gaggagctcg
2761 ccattgctaa ggctactgaa gaggacttct gtgaggaaga ggagatcaaa attcgccaga
2821 ggatctttcg ccccacaaga aaacaaagga aggaagaaag ggctacgtta ggactggtga
2881 ctggttcaga aatcagaagg aggaaccctg atgatttcaa gcccaaagga aagctgtggg
2941 ctgacgacaa cagaagtgtc gactacaatg aaaaactgga tttcgaggcc cccccgagca
3001 tttggtctag aatcgtcagt tttggctcag gttggggttt ctgggtgtca ccaagcctgt
3061 ttataacatc aactcatgtg attccttctg gtataacaga ggtgttcgga gtgcccgtta
3121 agcaagtcca aattcacaag tcaggcgaat tttgccgctt cagatttcca aaaccaatca
3181 gaacagatgt gacaggaatg atcctagaag agggggctcc agaaggcacc gtggcgacca
3241 tcctcatcaa acgccccacc ggcgagctca tgccacttgc tgccagaatg gggacgcacg
3301 caaccatgaa aattcaggga cgcatggtcg gtggacagat gggcatgttg ctcactggtt
3361 caaacgccaa aggcatggat ttagggacaa ctcccggaga ctgcggctgc ccgtatattt
3421 acaagagagg taacgattac atcgttatcg gagttcacac agcagccgcc cgtggaggga
3481 acactgtcat ctgtgctaca caagggagtg aaggtgaagc aacacttgag ggtggagatg
3541 ataaagggac atattgtggg gcacccatcc ttggtcctgg tggggcacca aaattgagca
3601 ccaagaccaa attctggaga tcatcaaaca cacccctccc accggggaca tatgaacctg
3661 cttaccttgg gggccgtgac ccacgtgtta agggcgggcc ctccctgcaa caagtcatga
3721 gggaccaact gaaaccattt accgaaccca ggggtaaacc tccaaaaccc agtgtcctag
3781 aggcagccaa acaaaccatc attaatgtcc tggaacagac cctggacccc ccacaaaagt
3841 ggacttacgc acaggcgtgc gcatcacttg acaaaaccac ctctagcggg cacccccacc
3901 acacccgaaa gaatgagttt tggaatggag agactttcac cggcaaacta gcagaccaag
3961 catcaaaagc gaacctaatg tttgaggaag ggaaacacat gacaccagtg tacacggcag
4021 cccttaagga tgagctggtc aagacagaca agatttatgg gaagatcaag aaaaggttgc
4081 tgtggggttc tgatctgtcc actatggtcc ggtgtgcaag agcttttggg ggactcatgg
4141 aggagatgaa ggcccactgc atatcactcc caatccgtgt tggcatgaac atgaatgaag
4201 atggcccaat aatatttgag aaacattcca ggtataaata tcattatgat gcagattact
4261 cccgatggga ctccactcaa cagagagatg tgttagctgc agctatggaa ataatggtta
4321 ggttctccgc tgaaccacaa ctatcacaaa aagtggctga agatttgttg gcccccagtg
4381 tggtggacgt cggagacttt aaaatttcaa taaatgaagg gctcccatcc ggtgtcccgt
4441 gcacctcaca gtggaattcc atcacacatt ggcttctaac tctctgtgct ctgtctgaaa
4501 ctaccaacct gtctcctgac atcatacagg caaattccat gttctcattc tatggtgatg
4561 acgagatcgt tagcaccgac atcaaattgg atccggaaaa attgaccaca aaattgagag
4621 agtatggctt gaaaccgact cgtccggata aaacagaagg acctctaatc attagtgagg
4681 atttggatgg actcaccttc ctccgaagaa cagtctcccg tgatccagct ggttggtttg
4741 ggaaattgga tcaaagttca atactcaggc aaatgtactg gaccagagga cccaaccatg
4801 aagaccccaa tgaaacaatg atacctcact ctcagaggcc catacaactc atggccctac
4861 ttggtgaagc ctctctacac ggaccctctt tttacagcaa aattagcaaa ttggtcataa
4921 ctgaactcaa ggaaggtgga atggattttt acgtgccaag acaagagcct atgttcaggt
4981 ggatgagatt ctctgacttg agcacgtggg agggcgatcg caatctggct cccagttttg
5041 tgaatgaaga tggcgtcgaa tgacgctact ccatcaaatg atggtgctgc cggcctcgtg
5101 ccagaaagta ataatgaggc aatggctctg gaacccgtgg tgggggcgtc tttagccgcc
5161 cctgtcactg gccaaactaa tataatagac ccctggatta gaactaattt tgtccaagcc
5221 cctaatggtg aatttacagt ttcccctaga aattcccctg gagagatatt ggtcaatttg
5281 gagttaggtc cagaactgaa cccttatctg gcacatttag ctaggatgta caatggttat
5341 gcgggtggta tggaggtgca agtgatgctc gcggggaacg cgttcactgc tggcaagatc
5401 atctttgccg ccgtgccacc ttactttcca gtggaaaatc ttagcccttc ccaaataaca
5461 atgttcccac atgtgatcat tgatgttaga accttagaac ctgtgctgct cccaatgcct
5521 gatgtcagaa gcaccctttt tcacttcaat caaaaggatg aacctaagat gagacttgtt
5581 gccatgcttt acacccctct tcgttctaat ggttctggtg acgacgtttt caccgtctca
5641 tgtaggatcc ttactaggcc ctcccctgaa tttgatttca catacttggt gccaccaaca
5701 gtggaatcaa agactaagcc attcacacta cctgtgctga cactgggaga actgtccaac
5761 tctagattcc ctctctctat tgatgaaatg gtcaccagcc ccaatgagtc catagttgtt
5821 cagccacaga atggtagggt cacactagat ggggaactgt taggcacaac ccaactgcaa
5881 gcatgtaaca tttgctccat aagggggaaa gtgacaggac aggtccctaa tgaacaacat
5941 atgtggaacc tggagatcac aaacctaaat gggacgcaat ttgaccctac agatgatgtc
6001 ccagcccctc ttggtgtgcc cgattttgca ggtgaggtct ttggtgtact cagccagaga
6061 aatagaggtg aaagcaaccc agcaaacagg gctcatgatg ctgtcgtggc tacctacagt
6121 gataaataca cccctaaatt gggcttagtg caaattggga cttggaacac caatgatgtt
6181 gaaaaccagc caacaaaatt caccccaatt ggtttgaatg aggtcgccaa tggccatcga
6241 tttgaacagt ggactttgcc taggtattct ggtgccctga cattaaatat gaatttagcc
6301 cctgctgtgg ccccgctctt tcctggagag cgtctccttt tcttccgctc ttatgtccca
6361 ttaaaaggtg gatttggaaa ccctgctata gattgtctag tgcctcagga gtgggtccaa
6421 catttctacc aggaatctgc cccatctctt ggggatgtgg ccttagtcag gtacgtcaac
6481 ccagacaccg ggcgcgtcct ttttgaggcc aaactccaca aaggtgggtt cctgaccgtg
6541 tcaagtacta gcacagggcc tgttgtggtc ccagccaatg gctatttcag gtttgactcc
6601 tgggttaatc aattttactc tcttgccccc atgggaactg ggaatgggcg cagaaggttt
6661 cagtaatggc aggagctttc atagcaggtt tagcaggtga tgtgcttagt aatggcctcg
6721 gttcgctgat taatgccgga gccaatgcta tcaatcaaag agcagaattt gattttaata
6781 ggcaattgca acaaaattct tttaatcatg ataaggagat gttaaatgcc caaattcaag
6841 caacaaaaca gttgcaggct gatatgatag caatcaaaca gggagtccta gctgctgggg
6901 gtttctcacc aactgatgca gccagaggag ctgtcaatgc acccatgacc caagcactag
6961 attggagtgg cactaggtac tgggcccctg gttcaatgaa gaccaccagc tattctggaa
7021 agtttgtgtc catgaatcct gttaggcagg ttgagttccc gcagcccaaa aagagtgcgg
7081 ccataccatc aagcgccagc tctgtgtctt ctggtaggac caatcttaca aattctaccc
7141 aatcaactgt tgttagcact tcctcagtgc caccttctag gggttcttct gccccttcta
7201 ctctgtcaag ggccacaact agaacttcca attgggttga ggagcaaaac aggaatttgg
7261 aaccctatat gaggggtgcc ctccaaacaa catttgtcac ccccccttcc agccgggcgt
7321 ctagcaatgg tacagtctca actgtaccaa aaggtgtttt ggactcctgg acacctgcgt
7381 ttaacacccg caggcagccg cttttcgctt accttcgtaa gaagggggag tcacaagttt
7441 agtgaaaaga taattaatga ttaataattg atctttt
//