Typing tool
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Typing tool
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Complete norovirus genomes
| MW305635 | GII.6 | |
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| GII.P7 |
ORF1: 1..5063
ORF2: 5044..6687
ORF3: 6687..7463
LOCUS MW305635 7515 bp RNA linear VRL 06-JUL-2021
DEFINITION Norovirus GII isolate Arg14711 nonstructural polyprotein (ORF1)
gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete
cds.
ACCESSION MW305635
VERSION MW305635.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7515)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses reveal coexistence of
viral populations evolving under recombination constraints
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7515)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7515
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Arg14711"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Argentina"
/collection_date="2016"
/note="genotype: GII.6[GII.P7]"
gene <1..5063
/gene="ORF1"
CDS <1..5063
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QPJ59241.1"
/translation="FGSQNSVNDSINTAPSNKEEVGAFSNIKVGFKKMLGAVPKGTKA
PSSDQHCPSVKIGTKTLTIPPEPPNGEDTVQFDAKSETVRGLPDLTTVQNEHENTPYT
VPPLSEREHRPATEPLPGTILEMWDGEFYHYSVYVSGGKALGVHKPPAAISLATIELT
PISLYWRPVYTPNYLVCPDTLKGLAGEKFPYTAFSNNCYNFCCWVLELNDTWLSRRSI
SRTTGFFKPYQSWNRKPLPTVDDGKIKKVANAILCALGSLFSKPIKDLLGKLKPLNLL
HLLASCDWTFAGIVETVILMAELFGIFWTPPDVSSFIASLIGDFELQGPEDLAVELVP
VVMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMKWFFPKKEEKAE
METLRAIEDAVLDMEAIGNNHLTTLLKDKDSLTAFMKTLDLEEEKARKLSTKSSSPDI
VGTINAILARIAAARSLLHKAKEEMFSRIRPVVVMISGRPGIGKTHMARHLAKSIANT
MSGDQRVGLVPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALTLQELADTCPVTLNCD
RIENKGKMFDSDVIIITTNLVNPAPLDYVNFEACSRRVDFLVYAESPEIEKVKRDFPG
QPDMWKDHFKPDFSHIKLTLAPQGGFDKNGNTPHGKGTMRSLTQGSLTARVAGLVHER
RDEFQLQGNDLQTYNFDTNRVSAFRKLAADNKYGIMETMRVGTALKSVKTLEDLKVAL
RDVKFNECEIIYRNSKYRVSSNGKGSVSVDKVEDQTSQTANEVGAALLRLRQARARYY
VSCFQDLVYTLIQVAGASFVVNRISKRFCWERWVRPTETQETSESEKEVAQGRWEIEP
KDTEPEGKKGKNKKGRGKKHTAFSSKGLSDEEYDEFKRIREERNGKYSIEEYLQDRDR
YYEEVAVARATEEDFCEEEEAKIRQRIFRPTKKQRKEERGVLGLVTGSDIRKRRPDDF
QPKGNLWADDTRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSNLLITTTHVLPKG
INELFGVEIKQIQIHKSGEFCRFRFPRPIRPDVTGLVLEEGAPEGTVCSILVKRPTGE
MIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDCGCPYIYKRGNDI
VVAGVHTAAARGGNTVICATQGQDGEAVLEGNENLGTYCGAPILGPGKAPKLSTKTKF
WRSSPDALPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEPRGKPPRPAVLEEA
KKTVMNVLEQTIDPAKPWTYSQACASLDKTTSSGSPHHVRKNDHWNGESFTGPLADQA
SKANLMYEQAKHVQPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGTMIRCARAFGGL
MDSMKASCIALPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDSTQQRNILSAAME
VMVRFSAEPELAQVVAEDLLAPSQLDVGDFVISVQEGLPSGVPCTSQWNSIAHWILTL
SAMAEVSGLSPDVVQAHSCFSFYGDDEIVSTDINLDPMKLTQKLREYGLVPTRPDKTE
GPLVITEDLTGLTFLRRSIARDPAGWYGKLDQDSILRQLYWTRGPNHENPYESMVPHS
QRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEAMFRWMRFSDLST
WEGDRNLAPEGVNEDGVE"
mat_peptide <1..971
/gene="ORF1"
/product="p48"
mat_peptide 972..2069
/gene="ORF1"
/product="NTPase"
mat_peptide 2070..2588
/gene="ORF1"
/product="p22"
mat_peptide 2589..2987
/gene="ORF1"
/product="VPg"
mat_peptide 2988..3530
/gene="ORF1"
/product="Pro"
mat_peptide 3531..5060
/gene="ORF1"
/product="RdRp"
gene 5044..6687
/gene="ORF2"
CDS 5044..6687
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ59242.1"
/translation="MKMASNDAAPSNDGAANLVPEATNEVMALEPVVGASIAAPVVGQ
QNIIDPWIRENFVQAPQGEFTVSPRNSPGEMLLNLELGPELNPYLSHLSRMYNGYAGG
MQVQVVLAGNAFTAGKIIFAAVPPHFPVENISAAQITMCPHVIVDVRQLEPVLLPLPD
IRNRFFHYNQENTPRMRLVAMLYTPLRANSGEDVFTVSCRVLTRPAPDFEFTFLVPPT
VESKTKPFTLPILTLGELSNSRFPAPIDMLYTDPNEAIVVQPQNGRCTLDGTLQGTTQ
LVPTQICSFRGTLISQTSRSADSTDSTPRARNHPLHVQLKNLDGTPYDPTDEVPAVLG
AIDFKGTVFGVASQRNTTGSSIGATRAHEVHIDTTNPRYTPKLGSVLMYSESTDFDDG
QPTRFTPIGMGADDWHQWELPEYSGHLTLNMNLAPAVAPAFPGERILFFRSMVPSAGG
YGSGHIDCLIPQEWVQHFYQEAAPSQSAVALIRYVNPDTGRNIFEAKLHREGFITVAN
SGNNPIVVPPNGYFRFEAWVNQFYTLTPMGTGQGRRRTQ"
gene 6687..7463
/gene="ORF3"
CDS 6687..7463
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ59243.1"
/translation="MAGAFLAGLAGDAITSGVGSLINAGANAINQKVEYDFNKQLQLA
SFKHDKEMLQSQVLATKQLQQEMMNIRQGVLSAGGFSPADAARGAVNAPMTKILDWNG
TRYFAPNSMKTTSYSGQFSSNPVHRQSTLPRSEPPKIKVNSDSASVYSSASTVPSQST
YSTVLTAGSSSSRTTSSSAAASTLSRTSDWVRGQNERLSPFMDGALQTTFVTPPSSKA
SSYGSVSTVPKAVLDSWTPMFNTHRQPLFAHVRRRGESQI"
ORIGIN
1 cctttggcag ccagaactct gtcaatgaca gtatcaacac cgccccttct aataaagaag
61 aggttggtgc attctccaac atcaaagttg gttttaagaa aatgctgggt gccgttccca
121 aggggaccaa agcacccagt agtgatcagc actgcccctc agttaagatc gggaccaaga
181 cattaacaat tccccctgag cccccaaatg gtgaagacac cgtgcagttt gatgcgaagt
241 cggaaactgt gcgcgggtta ccagacttga caacggtgca gaacgaacac gaaaacacac
301 catacactgt ccccccattg agcgaaaggg agcacagacc agctactgaa ccgcttcctg
361 gcacaatact ggagatgtgg gatggtgaat tctaccacta ctctgtgtac gtcagcggtg
421 gcaaggccct aggggttcac aagccccctg cagcgataag cctcgcgacg atagagctca
481 cacccatatc tctttattgg aggcccgttt acacccccaa ctatctggtc tgtccagaca
541 cgttgaaggg ccttgctggt gagaagttcc cctacacggc cttcagcaac aactgttaca
601 acttctgttg ctgggtgctt gagctcaatg acacgtggct tagcaggaga agcatttcta
661 ggaccaccgg cttcttcaaa ccataccagt cttggaatag gaaacccctt ccaacagttg
721 atgatggaaa gatcaaaaag gtggccaacg caattctctg tgcacttgga tcactgtttt
781 caaaaccaat caaggaccta ttgggcaaac ttaaaccatt gaacttgctg cacttgctcg
841 catcatgtga ctggacgttt gcgggtatag tagagacagt catcctaatg gcggaacttt
901 tcggcatctt ttggacaccg ccagatgttt ccagtttcat agcctccctg ataggtgatt
961 ttgaattgca agggccggag gacctggctg tggagcttgt acccgtggtc atgggtggca
1021 taggaatggt tctcggcttc actgctgaga agataggccg catgctatcg tccgctgcat
1081 caacactacg ggcgtgcaaa gacttgggga attatgctct tgacatattg aaactggtta
1141 tgaagtggtt cttcccaaag aaagaagaga aagccgagat ggaaacccta agggcgattg
1201 aggatgccgt cctggacatg gaagctatag gaaataacca tctcacaacc ctcctcaagg
1261 acaaggatag cctcacggct ttcatgaaga ctctagatct agaagaagag aaggcgagga
1321 agctgtccac caaatcatcc tcgccggaca ttgtcggcac cattaatgcc atactggcta
1381 gaatagctgc tgccaggtcc ctcttgcaca aggctaaaga agaaatgttc agtaggatca
1441 gacccgtggt tgtcatgatc tcgggtaggc ctggcattgg caaaacccac atggcaagac
1501 acttggctaa gagcatcgcc aacaccatga gcggcgacca gagagtgggg ctcgtcccac
1561 gcaacggggt cgatcattgg gacgcctaca ggggagagag ggtggtttta tgggatgatt
1621 atggcatggg aaaccctgtc aaagatgcct taacactaca agagctggcc gacacctgcc
1681 cagtaactct aaactgtgat aggattgaga acaaggggaa gatgtttgac agtgatgtca
1741 ttataatcac gaccaattta gtcaacccag cgcccctcga ttatgtaaac ttcgaggcgt
1801 gctccagaag ggtcgacttt ctggtctatg cagaatcgcc agaaattgag aaggttaaga
1861 gagacttccc cggccaacct gacatgtgga aggaccattt caaaccagac ttttcccaca
1921 taaaactaac tctagcccca cagggtggat ttgacaagaa tggcaacacc ccgcatggta
1981 agggcaccat gcgatcccta acccaggggt ccctgactgc aagggttgca ggtcttgttc
2041 atgagaggag agacgagttt cagctccagg ggaacgacct tcaaacatat aactttgata
2101 ccaacagagt ctctgcattt aggaagctgg ccgcagacaa caagtatggg atcatggaga
2161 ctatgagagt gggcacagcg cttaagagcg tcaagacctt ggaagatctg aaagttgcac
2221 tgagagatgt gaagttcaac gagtgcgaga taatttacag aaactccaaa taccgagtct
2281 cttccaatgg taaaggttct gtctctgttg acaaagttga ggaccaaaca tcccagaccg
2341 caaacgaagt gggtgcagca ctccttagac tcagacaggc aagagctagg tactatgtca
2401 gctgcttcca agacctcgtt tacactctaa tacaggtcgc cggagcatca ttcgttgtca
2461 acaggatctc taaaaggttc tgctgggaga gatgggtcag accaaccgag acccaggaaa
2521 cgagtgaatc cgaaaaggaa gtggcccaag gcagatggga gattgagccc aaggacacag
2581 aaccagaagg taagaagggt aagaacaaga aaggaagagg caagaaacac acagctttct
2641 ccagtaaagg actgagtgat gaggagtatg acgagttcaa gagaatcaga gaagaaagga
2701 acggaaaata ctccattgag gaatacctgc aagaccggga tcgctactat gaggaagtgg
2761 cagttgcccg ggcgacagag gaggacttct gtgaagagga ggaggccaag ataagacaaa
2821 gaatctttcg ccccacaaag aaacagagga aggaagaaag gggggtgctt ggtttggtta
2881 ctggctcaga catcaggaag agaagaccag acgattttca accgaagggc aacctgtggg
2941 cagacgacac caggagtgtg gactacaacg agagacttga tttcgaggcc cccccgagtg
3001 tctggtcaag aatagtccca ttgggcactg gctggggctt ctgggtctca tcaaacctcc
3061 tgatcacaac aacgcacgtc ctacctaagg ggattaatga actctttgga gttgagatca
3121 aacagattca gattcataag tctggagagt tctgcaggtt cagattccca agaccaatta
3181 gaccggatgt cacagggctc gtgttggagg aaggcgctcc agaaggcact gtctgctcca
3241 tactcgtaaa gagacctaca ggtgagatga tccccctggc agtgaggatg ggtacgcatg
3301 catccatgaa gatacagggt aggaccgtcg gtggccagat ggggatgctc ctcacagggg
3361 caaatgcgaa gaacatggat cttggcaccg gtcctggtga ctgcggttgc ccttacatct
3421 acaaacgtgg caatgatata gttgtcgcgg gtgtccacac cgcagcagcc cggggaggca
3481 acactgttat atgtgccact caagggcaag atggggaagc agtccttgag ggaaatgaga
3541 accttggcac ttactgtggt gctccaatct tgggtccagg caaggcgccc aaacttagca
3601 cgaagaccaa gttctggcgt tcatcaccag acgccttgcc gccaggcact tatgagcctg
3661 cctacttggg aggtaaggac cctagagtgg aaaaaggacc atccctgcag caagtcatga
3721 gggaccagtt aaaacctttc acagaaccca ggggcaagcc acctaggcct gcagtcttag
3781 aagaggccaa aaagacagtg atgaatgttc tagagcaaac cattgaccct gctaaaccat
3841 ggacctattc ccaagcatgt gcctcactgg acaagaccac ttccagtggt agcccccatc
3901 atgtcaggaa aaatgaccat tggaatgggg aatccttcac tggccccctc gcagaccaag
3961 catccaaagc caacctcatg tacgagcagg ccaagcatgt gcagcccgtg tacacggccg
4021 cacttaaaga tgaactagtc aaaaccgata agatctacaa gaagataaag aaaaggctct
4081 tgtgggggtc ggatcttggt acaatgatca ggtgtgccag ggcctttggc ggtctcatgg
4141 atagcatgaa ggcaagctgc atagccctcc catgtagggt aggaatgaac atgaatgaag
4201 atggccccat catatttgac aagcattcta agtataggta ccattatgat gctgactatt
4261 ccaggtggga ctcaacccag caaaggaaca ttctctcggc cgctatggaa gtgatggtgc
4321 ggttctctgc tgaaccagag ctggcacaag tggttgcaga ggacctcctg gcacccagcc
4381 aactagatgt tggcgacttc gtcatctcag tccaggaggg tctgccatca ggggtcccat
4441 gcacatcaca atggaattca atagcacact ggatcctaac cttgagtgca atggcagaag
4501 tgtcgggtct ctcaccagat gttgtccaag cccactcctg tttctcattc tacggtgatg
4561 atgagatcgt cagcactgac atcaaccttg accccatgaa gttgacacag aagctcagag
4621 agtatggcct ggtccccacc cgacctgaca aaactgaggg tcccctcgta ataactgaag
4681 atctcaccgg cctaacgttc ctgcgtaggt caattgcacg ggacccagct gggtggtatg
4741 gaaaattgga ccaagactca atcctcagac agttgtactg gacaaggggc cccaaccatg
4801 agaacccata cgagagcatg gtccctcatt cccagcgggc cacacaactt atggccctcc
4861 tcggtgaggc ctcactgcat ggtcctcagt tttacaagaa agttagcaag atggttatta
4921 atgagatcaa aagtggtggt ctggaattct atgtgcccag acaagaggcc atgttcagat
4981 ggatgagatt ctctgacctc agcacatggg agggcgatcg caatcttgct cccgagggtg
5041 tgaatgaaga tggcgtcgaa tgacgctgct ccatcgaatg atggtgctgc caacctcgta
5101 ccagaggcca ccaatgaggt tatggcactt gagccggtgg tgggagcctc aattgctgct
5161 cctgtcgtcg gccaacaaaa tataattgac ccctggatta gagaaaattt tgttcaggca
5221 ccacagggtg agtttactgt atcaccaagg aactcacctg gtgagatgct tctaaatctt
5281 gaattaggcc ctgagctcaa cccttatctg agtcatttgt cccgcatgta taatggctat
5341 gctggtggta tgcaggttca ggtggtccta gctgggaatg cgttcacagc tggtaaaatc
5401 atctttgccg ccgtcccacc acatttccct gttgagaaca ttagtgcagc ccaaatcaca
5461 atgtgccccc atgtaattgt tgatgtaaga cagcttgagc cagtgctttt gcccctccct
5521 gacataagga atagattctt tcattataat caggaaaata ccccccggat gagacttgtg
5581 gctatgttgt atacacccct tagagcaaat tctggtgagg atgtgtttac ggtgtcttgc
5641 agagtcctga cccgccctgc ccccgacttt gagttcacgt ttttggtgcc accaactgtg
5701 gagtcaaaga ccaagccctt tacactccct attctgactc ttggagagct gtccaactcc
5761 agattccccg ctccgataga catgttgtac actgacccca atgaggcaat tgtggtgcaa
5821 ccacaaaatg gcaggtgcac tctagatgga acacttcaag ggaccaccca actggtaccc
5881 acccaaattt gctccttcag gggcacgcta attagccaga cgtcgaggtc tgcagattca
5941 acagattcaa ccccacgggc gaggaaccac cctctccacg ttcagctgaa gaacctcgat
6001 gggacaccat atgacccaac agatgaggtg ccagcagttt tgggtgccat agatttcaaa
6061 ggaactgtgt ttggggtcgc tagccaaaga aacaccacgg ggagctctat aggagcaacc
6121 cgcgcccatg aagtgcacat agacaccaca aaccctagat acaccccaaa gcttggctct
6181 gtgttgatgt attctgaatc tactgatttt gatgatggac aacccacccg cttcaccccc
6241 attggtatgg gagccgatga ttggcaccaa tgggaattgc ccgaatattc tggtcacctc
6301 actcttaaca tgaatttggc ccctgcagtt gcccctgctt tccctggtga gcgcattctc
6361 ttcttcagat caatggtgcc gtctgctggt ggctatggat caggtcacat agattgcctc
6421 atcccacagg agtgggttca gcatttctac caggaggccg ctccatcaca gtctgcggtg
6481 gctcttatca gatatgtcaa ccctgacact ggaaggaaca tctttgaggc aaaactgcat
6541 agagaagggt ttatcactgt ggcaaattct ggaaacaacc ccatagttgt gcccccaaac
6601 ggttacttca ggtttgaggc ctgggttaat caattctata cactcacccc catgggaact
6661 ggacaggggc gcagaagaac tcaataatgg caggagcttt cttagctgga ttggcaggtg
6721 acgccataac aagtggtgtc gggtccctaa tcaatgctgg ggccaatgca attaaccaaa
6781 aggtagaata tgactttaat aaacagctcc aattggcatc cttcaaacat gacaaagaga
6841 tgttgcaatc acaagtgctg gccactaaac agctccagca ggagatgatg aacataaggc
6901 aaggggtctt gtccgctggc ggcttctccc ctgcagatgc cgcgagaggt gctgtgaacg
6961 cgccgatgac aaaaattttg gattggaatg gaacaaggta ctttgcccca aatagtatga
7021 agacaaccag ttattcgggc cagttttcca gcaaccctgt gcataggcag tccactttgc
7081 cccgttctga acccccaaaa attaaagtta atagtgattc tgctagtgtg tatagttctg
7141 catctactgt tccttcacaa tcaacttact caacggtttt gactgcgggg tctagctcat
7201 ctaggacaac atcttcttct gcagcagctt ccaccctatc taggactagt gactgggtga
7261 gaggacaaaa tgaaaggctt agcccgttta tggatggtgc tctccaaaca acttttgtca
7321 caccaccatc gagcaaagct tcatcatatg ggtcggtctc aaccgttccc aaagctgttt
7381 tggactcctg gactcctatg ttcaataccc ataggcagcc tctcttcgct catgtgcgca
7441 ggcgagggga gtcacagatt tagtgaaaag attgattagg ttttctttct ttcttctttt
7501 ccttttcttt ctttt
//