Typing tool
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Typing tool
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Complete norovirus genomes
| MW305620 | GII.7 | |
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| GII.P7 |
ORF1: 1..5032
ORF2: 5013..6635
ORF3: 6635..7408
LOCUS MW305620 7465 bp RNA linear VRL 18-JUL-2024
DEFINITION Norovirus GII isolate Arg12771 nonstructural polyprotein (ORF1)
gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete
cds.
ACCESSION MW305620
VERSION MW305620.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7465)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A.U.A., Ford-Siltz,L.A., Green,K.Y.,
Galeano,M.E., Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N.,
Ushijima,H. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses provide insights on
evolutionary dynamics and evidence of coexisting viral populations
evolving under recombination constraints
JOURNAL PLoS Pathog 17 (7), e1009744 (2021)
PUBMED 34255807
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 7465)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7465
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Arg12771"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Argentina"
/collection_date="2014"
/note="genotype: GII.7[GII.P7]"
gene <1..5032
/gene="ORF1"
CDS <1..5032
/gene="ORF1"
/codon_start=2
/product="nonstructural polyprotein"
/protein_id="QPJ59196.1"
/translation="NNATPSNKEEVGAFSNIKVGFKKMLGAVPKGTKAPSSGQHCPTV
KIGPKTLTIPPEPPNGEDTVQFDAKSETIIGLPDLTTVQNEHENTPYTVPPLSEREHR
PATEPLPGTILEMWDGEFYHYSVYVSDGKALGVHKPPAAISLATIELTPISLYWRPVY
TPNYLVSPDTLKGLAGEKFPYTAFSNNCYNFCCWVLELNDTWLNRRCISRTTGFFKPY
QSWNRKPLPTVDDGKIKKVANAILCALGSLFSKPIKDLLGKLKPLNLLHLLASCDWTF
AGIVETVILMAELFNVFWTPPDVSNFVASLIGDFELQGPEDLAVELVPVVMGGIGMVL
GFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMKWFFPKKEEKAEMETLRAIEDA
VLDMEAIGNNHLTTLLKDKDSLTAFMKTLDLEEEKARKLSTKSSSPDIVGTINAILAR
IAAARSLLHKAKEEMFSRIRPVVVMISGRPGIGKTHMARHLAKSIANTMSGDQRVGLV
PRNGVDHWDAYRGERVVLWDDYGMGSPVKDALTLQELADTCPVTLNCDRIENKGKMFD
SDVIIITTNLVNPAPLDYVNFEACSRRVDFLVYAESPEIEKVKRDFPGQPDMWKDHFK
PDFSHIKLTLAPQGGFDKNGNTPHGKGTMRSLTQGSLTARVAGLVHERRDEFQLQGND
LQIYNFDTNRVSAFRKLAADNKYGIMETMRVGAALKNVKTLEDLKIALRDVKFNECEI
IYKNSKYRVSSNGKGSVSVDKVEDNASQTVNEVQSAILRLRQARARYYISCFQDLVYT
LIQVAGASFVVSRISRRFCWERWVKPTETQEVNDSEKEVAQSRWEIEPKDTEPEGKKG
KNKKGRGKKHTAFSSKGLSDEEYDEFKRIREERNGKYSIEEYLQDRDRYYEEVAVARA
TEEDFCEEEEAKIRQRIFRPTKKQRKEERGVLGLVTGSDIRKRRPDDFQPKGNLWADD
TRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSNLLITTTHVLPKGVKELFGVEIK
QIQVHKSGEFCRFRFPRPIRPDVTGLVLEEGAPEGTVCSILIKRPTGEMIPLAVRMGT
HASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDCGCPYIYKRGNDIVVAGVHTAAA
RGGNTVICATQGQDGEAVLEGNEDLGTYCGAPILGPGKAPKLSTKTKFWRSSPDALPP
GTYEPAYLGGKDPRVEKGPSLQQVMRDQLRPFTEPRGKPPRPAVLEEAKKTVMNVLEQ
TIDPAKPWSYLQACASLDKTTSSGSPHHVKKNDHWNGESFTGPLADQASKANLMYEQA
KHVQPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGTMIRCARAFGGLMDSMKASCIA
LPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDSTQQRSILSAAMEVMVRFSAEPE
LAQVVAEDLLAPSQLDVGDFVISVQEGLPSGVPCTSQWNSIAHWILTLSAMAEVSGLS
PDVVQAHSCFSFYGDDEIVSTDINFDPMKLTQKLREYGLVPTRPDKTEGPLVITEDLT
GLTFLRRSIARDPAGWFGKLDQDSILRQLYWTRGPNHENPYESMVPHSQRATQLMALL
GEASLHGPHFYKKVSKMVINEIKSGGLEFYVPRQEAMFRWMRFSDLSTWEGDRNLAPE
GVNEDGVE"
mat_peptide <1..940
/gene="ORF1"
/product="p48"
mat_peptide 941..2038
/gene="ORF1"
/product="NTPase"
mat_peptide 2039..2557
/gene="ORF1"
/product="p22"
mat_peptide 2558..2956
/gene="ORF1"
/product="VPg"
mat_peptide 2957..3499
/gene="ORF1"
/product="Pro"
mat_peptide 3500..5029
/gene="ORF1"
/product="RdRp"
gene 5013..6635
/gene="ORF2"
CDS 5013..6635
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ59197.1"
/translation="MKMASNDAAPSNDGAAGLVPEINNEVMPLEPVAGASLATPVVGQ
QNIIDPWIRNNFVQAPAGEFTVSPRNSPGEILLDLELGPELNPYLAHLARMYNGHAGG
MEVQIVLAGNAFTAGKIIFAAIPPGFPYENLSPSQITMCPHVIIDVRQLEPVLLPMPD
IRNNFFHYNQGNDPKLKLIAMLYTPLRANNSGDDVFTVSCRVLTKPSPDFEFTFLVPP
TVESKTKQFTLPILKISEMTNSRFPVPVEMMYTARNENQVVQPQNGRVTLDGELLGTT
PLLAVNICKFKGEVIAKNGDVRSYRMDMEITNTDGTPIDPTEDTPGPIGSPDFQGILF
GVASQRNKNEQNPATRAHEANINTGGDQYAPKLAQVKFFSESQDFEVHQPTVFTPVGV
AGDTSHPFRQWVLPRYGGHLTNNTHLAPAVAPLFPGEQILFFRSQIPSSGGHELGYVD
CLVPQEWVQHFYQEAATAQSEVALIRFINPDTGRVLFEAKLHKQGFITVAHTGDNPIV
MPPNGYFRFEAWVNQFYSLAPVGTGNGRRRIQ"
gene 6635..7408
/gene="ORF3"
CDS 6635..7408
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ59198.1"
/translation="MASAFLANLAGGVASNGISSLINAGANAINQKVEFDYNKQLQNA
SFSHDKEMLQAQIEATKRLQQEMIDIKQGVLTAAGFSPTDAARGSVGAPMTKLVDWSG
TRYWAPGAMRTTGYSGTFTHLPPVQSASYVNNQNRQPLKVDSSPPSSSGSSVSSVKTQ
STTLSGTSRVGSSSQSTLSTRPSTRTSDWVRSQNERLSPFMDGALQTTYVTPPSSRAS
SVSTVSTVPKEVLDSWTPMFNTHRQPLFAHLRRRGESQI"
ORIGIN
1 taataacgcc accccttcta ataaagaaga ggttggtgca ttctccaaca taaaagttgg
61 attcaagaaa atgctgggtg ccgttcccaa gggtaccaaa gcacccagca gtggtcaaca
121 ttgccccaca gtcaagatcg ggcctaaaac tttaacaatc ccccctgagc ccccaaatgg
181 tgaagacacc gtacagtttg atgcaaagtc agaaactata attggattgc cggacttgac
241 aacggtgcaa aatgaacatg aaaacacccc atacactgtc cctccattaa gtgagaggga
301 acacagaccg gctaccgagc cacttcctgg cacaatattg gaaatgtggg atggtgagtt
361 ctaccattat tccgtgtacg tcagcgacgg caaagctctg ggggtccaca aaccaccggc
421 agctataagc ctcgcgacga tagagctcac ccccatatca ctttactgga ggcccgttta
481 tacccccaat tacttggtct ccccggacac attaaagggt cttgctggtg agaagtttcc
541 ctatacggcc ttcagtaaca actgttataa cttttgttgt tgggtgcttg agctcaacga
601 cacgtggctt aacagaagat gcatttccag aactaccggc ttcttcaagc cataccagtc
661 ttggaacaga aaacctctcc caaccgttga tgatggaaag attaaaaagg tggccaacgc
721 aatcctctgt gcactcggtt cactgttctc aaaaccaatt aaagacctgt taggtaaact
781 caagccattg aatctgctgc acttgcttgc gtcttgtgat tggacgtttg cgggtatagt
841 ggagacagtc atcttgatgg cggagctttt caatgtattt tggacccccc cagatgtctc
901 taattttgta gcctccctaa taggtgattt tgaattacaa gggcctgagg acctggctgt
961 ggagctcgtc cccgtggtta tgggcggcat agggatggtt ctcggtttca ccgccgagaa
1021 gataggccgc atgctgtcgt ccgctgcatc aacactgcgg gcgtgcaaag acctagggaa
1081 ctatgccctt gacatactca aattggtcat gaagtggttc ttcccgaaga aggaagagaa
1141 agctgagatg gaaaccttga gggcgattga agatgccgtc ctagatatgg aagctatagg
1201 gaacaaccac ctcacaaccc ttctcaagga caaagatagc ctcacggctt tcatgaagac
1261 cctggatctg gaagaggaga aggcgaggaa actgtccact aaatcatctt caccggacat
1321 agtcggcacc atcaatgcca tactggctag gatagctgct gctagatccc ttctacataa
1381 ggctaaagag gagatgttca gcaggatcag gccagtggtt gttatgatct caggcaggcc
1441 tggcattgga aaaacccaca tggcgagaca cttggctaag agcatcgcca acaccatgag
1501 tggcgaccag agagtcgggc tcgttccgcg caacggcgtc gatcactggg atgcctacag
1561 aggagagagg gtggtcttgt gggatgacta cggcatgggg agccccgtta aggacgctct
1621 aacactacaa gagctggccg acacatgccc agtcacttta aattgtgaca ggattgagaa
1681 caaggggaag atgtttgaca gtgatgtcat cataatcacg accaacctag tcaaccccgc
1741 gcccctcgac tatgtgaact tcgaggcgtg ttctaggaga gttgacttcc tggtctatgc
1801 agagtcacca gaaattgaaa aggtcaagag agacttccct ggccagcctg acatgtggaa
1861 agaccatttt aaaccagact tctcccacat caagctgact ctagcccccc agggtgggtt
1921 tgataaaaat ggcaacaccc cacacggcaa gggaaccatg cggtccctaa cccaggggtc
1981 cctgactgcg agagttgcag gccttgtcca tgagaggaga gatgaattcc agctccaagg
2041 aaatgacctc caaatataca attttgacac caacagagtc tccgcattca ggaaattggc
2101 tgcagataac aagtatggga tcatggagac aatgagggtg ggtgcggcac tcaagaatgt
2161 gaagaccctg gaagatctta aaattgcatt gagggatgta aaattcaatg agtgtgaaat
2221 aatctacaag aactctaagt atcgggtctc ttccaacggt aaaggctcag tttctgttga
2281 caaagttgag gacaatgcat cccagactgt aaacgaggta caatcagcaa ttctcaggct
2341 caggcaagcg agggccagat attacatcag ctgcttccaa gacctcgtct acactctcat
2401 acaggttgcc ggagcatcat tcgttgtcag caggatctcc agaaggttct gctgggaaag
2461 gtgggtcaaa ccgaccgaga cccaggaggt gaatgattcc gaaaaggaag tggcacaaag
2521 cagatgggaa attgaaccca aggatacaga accagaaggc aagaagggta agaataagaa
2581 aggaaggggt aagaaacaca cagctttctc tagcaaaggc ctgagtgatg aagagtatga
2641 cgagttcaag agaatcaggg aagaaagaaa cggaaagtac tccattgagg aatacctgca
2701 agaccgggac cgctattatg aagaagtggc agttgcccgg gcgacagagg aggacttttg
2761 tgaagaggaa gaggccaaga taagacaaag aattttccgc ccgacaaaga aacagaggaa
2821 ggaggagagg ggtgtgcttg gcttagtcac cggctcagac atcaggaaga ggagaccaga
2881 tgatttccaa ccaaaaggca acctatgggc agatgacacc agaagcgtgg actataatga
2941 gaggcttgac tttgaggcgc ccccgagtgt ttggtcaaga atagtcccat taggcactgg
3001 ttggggattc tgggtttcat ccaaccttct gatcactaca acacacgtcc tgcctaaagg
3061 ggttaaggag ctctttggag ttgaaatcaa gcaaatccaa gttcataagt ctggagagtt
3121 ttgcaggttc agattcccaa gacctatcag gccagatgtc acaggacttg tgctggagga
3181 aggcgcccct gaaggtactg tctgttctat actcataaaa agacccacag gtgagatgat
3241 ccccttagca gtgaggatgg gcacacatgc atccatgaaa atacagggta ggaccgtcgg
3301 tggccagatg ggaatgcttc tcacaggagc aaacgcgaag aacatggatc tcggcaccgg
3361 tcctggtgac tgcggttgtc cttacatcta caaacgtggc aacgacattg ttgtcgcagg
3421 tgttcatacc gcagcagcac gaggaggcaa cactgttata tgtgccaccc aagggcaaga
3481 tggggaagca gtccttgagg ggaatgagga ccttggcacc tattgtggcg ccccaatttt
3541 gggccccggc aaggcgccta aactcagcac gaagaccaag ttttggcgtt catcaccaga
3601 tgccttacca cctggcacat atgaacctgc ttacctaggg ggcaaagacc ctagagtgga
3661 aaaaggtcct tcccttcaac aagtcatgag agatcagttg agacccttca cagaacccag
3721 gggcaaacca cctagacctg cagttttgga ggaagccaaa aagacagtga tgaatgttct
3781 agaacaaacc attgaccccg ccaagccatg gtcctatttg caggcatgtg cctcactgga
3841 caaaaccacc tccagtggta gtccccatca tgttaagaaa aatgaccact ggaatgggga
3901 gtccttcact ggcccacttg cagatcaggc atctaaagcc aacctcatgt atgagcaggc
3961 taagcatgtg cagcccgtgt atacggccgc gctcaaagat gagcttgtta agactgacaa
4021 gatctacaaa aagataaaga agaggctcct atgggggtcg gaccttggca caatgatcag
4081 gtgcgccagg gcctttggtg gtctcatgga cagcatgaag gcaagctgta tagctcttcc
4141 ttgcagggta gggatgaaca tgaatgaaga tggccctatt atatttgaca aacattctaa
4201 gtacaggtac cactatgatg ctgattattc taggtgggac tcaacccaac aaaggagcat
4261 tctttctgcc gctatggaag tgatggtgcg gttctctgct gaaccagaat tggcacaagt
4321 ggttgcagag gaccttttag cacctagcca gcttgacgtt ggcgattttg tcatctcagt
4381 ccaggagggt ctgccatcag gagtcccatg cacatcacaa tggaattcaa tagcacactg
4441 gatcctaact ttgagtgcaa tggcagaagt atcaggtctc tcaccagatg tcgtccaagc
4501 tcactcttgt ttttcctttt atggggacga cgagattgtc agtactgaca tcaactttga
4561 ccccatgaag ttgacacaga aactcaggga gtatggtctg gttcccactc ggcctgataa
4621 aactgaaggt cccctcgtca taactgaaga cctcaccggc ctgacgttcc tccgtaggtc
4681 gattgctcgg gacccagctg gttggtttgg aaagctggac caagactcaa tccttaggca
4741 gctgtactgg acaagggggc ctaaccatga gaacccatat gagagcatgg ttcctcattc
4801 tcagcgggcc acacaactca tggcccttct tggtgaggcc tcactacatg gtccccattt
4861 ttacaagaaa gttagcaaga tggttatcaa tgagattaag agtggtggtc tggagtttta
4921 tgtgcccaga caagaggcca tgttcaggtg gatgagattc tctgacctca gcacatggga
4981 gggcgatcgc aatcttgctc ccgaaggtgt gaatgaagat ggcgtcgaat gacgcagctc
5041 catctaatga tggtgcagca ggcctcgtac cagagatcaa caatgaggtc atgccccttg
5101 agcccgtggc tggtgcatcg ctggcgacac cagttgtcgg gcaacagaat ataattgatc
5161 cctggataag aaataatttt gtacaagctc ctgcaggtga gtttacagtc tcccctagaa
5221 attcccctgg tgaaattttg cttgatttgg agttgggacc agaactgaac ccctatctcg
5281 ctcatctggc ccgtatgtac aatgggcacg ctggtggcat ggaagtgcaa attgtgttgg
5341 ctgggaatgc gttcacagct ggcaagatca tatttgctgc catccctcca gggttcccat
5401 atgaaaattt gtcaccttca caaattacaa tgtgccctca tgttataatt gatgttagac
5461 agttagaacc agtcctatta cctatgccag atattagaaa taatttcttc cattacaatc
5521 agggcaatga cccaaaattg aaattgatag ccatgctcta caccccttta agggctaaca
5581 attctggtga tgatgtgttc acagtttctt gtagggtcct cactaaaccg tcacctgatt
5641 ttgaattcac atttttggtc ccccctacgg ttgaatctaa gaccaaacag ttcacattgc
5701 ccatcctcaa aatatcggag atgaccaact caagattccc agttccagtg gaaatgatgt
5761 acacagccag gaatgagaac caagttgtcc agccacagaa tggtagggtc acactcgatg
5821 gcgagctatt aggcaccaca cccttgttgg ctgtcaacat ctgcaaattc aagggggagg
5881 ttatagctaa gaatggagat gtgagatcct ataggatgga catggaaatc accaacactg
5941 atggcacccc aattgacccc acggaagaca cacctggtcc cattggttca cctgactttc
6001 aaggtatact ctttggcgtt gccagtcaac gcaacaagaa tgagcagaac cctgctacga
6061 gagcccatga agccaatatt aacactggtg gggaccaata tgcccccaaa ttggcccaag
6121 tgaaattctt ctcagagtcc caggatttcg aggtgcacca gcccacagtt ttcaccccag
6181 ttggtgtggc aggcgacacc tcccaccctt tcagacagtg ggtcctgcct cgatacggtg
6241 gacatctcac caacaacacc catttggctc cagcagtggc ccccctattc ccaggtgagc
6301 agattctatt ctttagatca caaataccca gctcaggtgg ccatgaattg ggttacgtgg
6361 actgccttgt cccacaagaa tgggttcaac acttctacca agaagctgcc acagctcagt
6421 ctgaggtggc gctcataagg ttcatcaacc cagacactgg cagagtcctc tttgaggcca
6481 agttgcacaa gcaaggcttt ataactgtgg ctcacactgg tgataaccca attgtcatgc
6541 caccaaatgg gtactttaga tttgaagcct gggttaatca gttttactca ctcgcccccg
6601 tgggaactgg gaatgggcgc aggaggattc aataatggcc agtgctttcc tagcaaattt
6661 ggcaggaggc gttgcctcca atggaattag ttcactcata aatgctgggg ctaacgctat
6721 taaccaaaag gttgagtttg attacaataa acaactccaa aatgcatcct tctcccatga
6781 taaggaaatg ctccaagccc aaattgaagc cactaaacgt ctgcaacaag agatgattga
6841 cataaaacaa ggggtgctga cagctgcggg attctcccct acggatgccg cgaggggttc
6901 tgtcggcgcg ccaatgacaa aattagttga ttggagtggc actagatatt gggcgcctgg
6961 tgctatgagg acaacaggtt attcagggac ttttactcac ttgccccctg tgcagtctgc
7021 ttcatatgtt aataatcaaa acagacaacc tcttaaagta gattcttctc ctccttcttc
7081 gagtggttct tctgtctctt ctgtcaagac acaatcaact accctctcag gcacttcaag
7141 ggtgggctcc tcatctcagt caaccctatc gaccaggccg agcacaagga catctgattg
7201 ggtgcgcagc cagaatgaaa ggttgagtcc cttcatggat ggagcgttgc aaacaacgta
7261 tgtaacgcca ccgtccagta gggcatcaag tgtcagcaca gtctcgaccg tgccgaaaga
7321 ggttttggac tcctggacgc ctatgtttaa cactcacagg cagccactct tcgcccattt
7381 gcgtaggcga ggggagtcac agatttagtg aaaagattgg ttaggaaaat tgattagttt
7441 gttcttcttt tctattattc cttta
//