Typing tool
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Typing tool
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Complete norovirus genomes
| MW305618 | GII.6 | |
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| GII.P7 |
ORF1: 1..5063
ORF2: 5044..6687
ORF3: 6687..7463
LOCUS MW305618 7515 bp RNA linear VRL 06-JUL-2021
DEFINITION Norovirus GII isolate Arg11943 nonstructural polyprotein (ORF1)
gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete
cds.
ACCESSION MW305618
VERSION MW305618.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7515)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses reveal coexistence of
viral populations evolving under recombination constraints
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7515)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7515
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="Arg11943"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Argentina"
/collection_date="2014"
/note="genotype: GII.6[GII.P7]"
gene <1..5063
/gene="ORF1"
CDS <1..5063
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QPJ59190.1"
/translation="FGSQNSVNDSINTAPSNKEEVGAFSNIKVGFKKMLGAVPKGTKA
PSSDQHCPSVKIGTKTLTVPPEPPNGEDTVQFDAKSETVRGLPDLTTVQNEHENTPYT
VPPLSEREHRPATEPLPGTILEMWDGEFYHYSVYVSGGKALGVHKPPAAISLATIELT
PISLYWRPVYTPNYLVCPDTLKGLAGEKFPYTAFSNNCYNFCCWVLELNDTWLSRRNI
SRTTGFFKPYQSWNRKPLPTVDDGKIKKVANAILCALGSLFSKPIKDLLGKLKPLNLL
HLLASCDWTFAGIVETVILMAELFGIFWTPPDVSSFIASLIGDFELQGPEDLAVELVP
VVMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMKWFFPKKEEKAE
METLRAIEDAVLDMEAIGNNHLTTLLKDKDSLTAFMKTLDLEEEKARKLSTKSSSPDI
VGTINAILARIAAARSLLHKAKEEMFSRIRPVVVMISGRPGIGKTHMARHLAKSIANT
MSGDQRVGLVPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALTLQELADTCPVTLNCD
RIENKGKMFDSDVIIITTNLVNPAPLDYVNFEACSRRVDFLVYAESPEIEKVKRDFPG
QPDMWKDHFKPDFSHIKLTLAPQGGFDKNGNTPHGKGTMRSLTQGSLTARVAGLVHER
RDEFQLQGNDLQTYNFDTNRVSAFRKLAADNKYGIMETMRVGTALKSVKTLEDLKVAL
RDVKFNECEIIYRSSKYRVSSNGKGSVSVNKVEDQTSQAANEVGAALLRLRQARARYY
VSCFQDLVYTLIQVAGASFVVNRISKRFCWERWVKPTETQETSESEKEVAQGRWEIEP
KDTEPEGKKGKNKKGRGKKHTAFSSKGLSDEEYDEFKRIREERNGKYSIEEYLQDRDR
YYEEVAVARATEEDFCEEEEAKIRQRIFRPTKKQRKEERGVLGLVTGSDIRKRRPDDF
QPKGNLWADDTRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSNLLITTTHVLPKG
INELFGVEIKQIQIHKSGEFCRFRFPRPIRPDVTGLVLEEGAPEGTVCSILVKRPTGE
MIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDCGCPYIYKRGNDI
VVAGVHTAAARGGNTVICATQGQDGEAVLEGNENLGTYCGAPILGPGKAPKLSTKTKF
WRSSPDALPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEPRGKPPRPAVLEEA
KKTVMNVLEQTIDPAKPWTYSQACASLDKTTSSGSPHHVRKNDHWNGESFTGPLADQA
SKANLMYEQAKHVQPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGTMIRCARAFGGL
MDSMKASCIALPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDSTQQRSILSAAME
VMVRFSAEPELAQVVAEDLLAPSQLDVGDFVISVQEGLPSGVPCTSQWNSIAHWILTL
SAMAEVSGLSPDVVQAHSCFSFYGDDEIVSTDINLDPMKLTQKLREYGLVPTRPDKTE
GPLVITEDLTGLTFLRRSIARDPAGWFGKLDQDSILRQLYWTRGPNHENPYESMVPHS
QRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEAMFRWMRFSDLST
WEGDRNLAPEGVNEDGVE"
mat_peptide <1..971
/gene="ORF1"
/product="p48"
mat_peptide 972..2069
/gene="ORF1"
/product="NTPase"
mat_peptide 2070..2588
/gene="ORF1"
/product="p22"
mat_peptide 2589..2987
/gene="ORF1"
/product="VPg"
mat_peptide 2988..3530
/gene="ORF1"
/product="Pro"
mat_peptide 3531..5060
/gene="ORF1"
/product="RdRp"
gene 5044..6687
/gene="ORF2"
CDS 5044..6687
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ59191.1"
/translation="MKMASNDAAPSNDGAANLVPEATNEVMALEPVVGASIAAPVVGQ
QNIIDPWIRENFVQAPQGEFTVSPRNSPGEMLLNLELGPELNPYLSHLSRMYNGYAGG
MQVQVVLAGNAFTAGKIIFAAVPPHFPVENISAAQITMCPHVIVDVRQLEPVLLPLPD
IRNRFFHYNQENTPRMRLVAMLYTPLRANSGEDVFTVSCRVLTRPAPDFEFTFLVPPT
VESKTKPFTLPILTLGELSNSRFPAPIDMLYTDPNEAIVVQPQNGRCTLDGTLQGTTQ
LVPTQICSFRGTLISQTSRSADSTDSAPRARNHPLHVQLKNLDGTPYDPTDEVPAVLG
AIDFKGTVFGVASQRNTTGNPTGATRAHEVHIDTTNPRYTPKLGSVLMYSESTDFDDG
QPTRFTPIGMGADDWHQWELPKYSGHLTLNMNLAPAVAPAFPGERILFFRSVVPSAGG
YGSGHIDCLIPQEWVQHFYQEAAPSQSAVALIRYVNPDTGRNIFEAKLHREGFITVAN
SGNNPIVVPPNGYFRFEAWVNQFYTLTPMGTGQGRRRVQ"
gene 6687..7463
/gene="ORF3"
CDS 6687..7463
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ59192.1"
/translation="MAGAFLAGLAGDAITSGVGSLINAGANAINQKVEYDFNKQLQLA
SFKHDKEMLQSQVLATKQLQQEMMNIRQGVLSAGGFSPTDAARGAVNAPMTKILDWNG
TRYFAPNSMKTTSYSGQFSSNPVHRQPTLPRSEPPKIKVNSDSASVYSSASTAPSQST
HSTALTAGSSSSRTTSSSAVASTLSRTGDWVRGQNERLSPFMDGALQTTFVTPPSSKA
SSYGSVSTVPKAVLDSWTPMFNTHRQPLFAHVRRRGESQI"
ORIGIN
1 cctttggcag ccaaaactct gtcaatgaca gtatcaacac cgccccttct aataaagaag
61 aggttggtgc attctccaac atcaaagttg gttttaagaa aatgctgggt gccgttccca
121 aggggaccaa agcacccagc agtgatcagc actgcccctc agttaagatt gggaccaaga
181 cattaacagt tccccctgag cccccaaatg gtgaagacac cgtgcagttt gatgcgaagt
241 cggaaactgt gcgcgggtta ccagacttga caacggtgca gaatgaacac gaaaacacac
301 catacactgt ccctccattg agtgaaaggg aacacagacc agctactgaa ccgcttcctg
361 gcacaatact ggagatgtgg gatggtgaat tctaccatta ctctgtgtac gtcagcggtg
421 gcaaagccct aggggttcac aagccccctg cagcgataag cctcgcgacg atagagctca
481 cacccatatc tctttattgg aggcccgttt acactcccaa ctatctggtc tgcccagaca
541 cgttgaaggg ccttgctggt gagaagttcc cctacacggc cttcagcaac aactgttaca
601 acttctgttg ctgggtgctt gagctcaatg acacgtggct tagcaggaga aacatctcta
661 ggaccaccgg cttcttcaaa ccataccagt cttggaatag gaaacccctt ccaaccgttg
721 atgatggaaa gatcaaaaag gtggccaacg caattctctg cgcacttgga tcactgtttt
781 caaaaccaat caaggaccta ttgggcaaac ttaaaccatt gaacttgctg cacttgctcg
841 catcatgtga ctggacgttt gcgggtatag tagagacagt catcctaatg gcggaacttt
901 tcggcatctt ttggacaccg ccagatgttt ccagtttcat agcctccctg ataggtgatt
961 ttgaattgca agggcctgag gacctggctg tggagcttgt acccgtggtc atgggtggca
1021 taggaatggt tctcggcttt actgctgaga agataggccg catgctatcg tccgctgcat
1081 caacactacg ggcgtgcaaa gacttgggga attatgctct tgacatattg aaactggtta
1141 tgaagtggtt cttcccaaag aaagaagaga aagccgagat ggaaacccta agggcgattg
1201 aggatgccgt cctggacatg gaagctatag gaaataacca tctcacaacc ctcctcaagg
1261 acaaggatag cctcacggct ttcatgaaga ctctagatct agaagaagag aaggcgagga
1321 agctgtccac caaatcatcc tcgccagaca ttgtcggcac cattaatgcc atactggcta
1381 gaatagctgc tgccaggtcc ctcttacaca aggctaaaga agaaatgttc agcaggatca
1441 gacccgtggt tgtcatgatc tcgggtagac ctggcattgg caaaacccac atggcaagac
1501 acttggctaa gagtatcgcc aacaccatga gcggcgacca gagagtgggg ctcgtcccac
1561 gcaacggggt tgatcattgg gacgcctaca ggggagagag ggtggtttta tgggatgatt
1621 atggcatggg aaaccctgtc aaagatgccc taacactgca agagctggcc gacacctgcc
1681 cagtaactct aaactgtgat aggattgaga acaaggggaa gatgtttgac agtgatgtca
1741 tcataatcac gaccaattta gtcaacccag cgcccctcga ttatgtaaac ttcgaggcgt
1801 gctccagaag ggtcgacttt ctggtctatg cagagtcgcc agaaattgag aaggttaaga
1861 gagacttccc cggccaacct gacatgtgga aggaccattt taagccagac ttttcccaca
1921 taaaactgac tctagcccca cagggtggat ttgacaagaa tggcaacacc ccgcatggta
1981 agggcaccat gcgatcccta acccaggggt ccctgactgc aagggttgca ggtcttgttc
2041 atgagaggag agacgagttc cagctccagg ggaacgacct tcaaacatat aactttgata
2101 ccaacagagt ctctgcattt aggaagctgg ccgcagacaa caagtatggg atcatggaga
2161 ctatgagagt gggcacagcg cttaagagtg tcaagacctt ggaagatctg aaagttgcgc
2221 tgagggatgt gaagttcaat gagtgtgaga taatttacag aagctccaaa taccgagtct
2281 cttccaatgg taaaggttct gtctctgtta acaaagttga ggaccaaaca tcccaggccg
2341 caaacgaagt gggtgcagca ctccttagac tcagacaggc aagggccagg tactatgtca
2401 gctgcttcca agacctcgtt tacactctaa tacaggtcgc cggagcatca ttcgttgtca
2461 acaggatctc taaaaggttc tgttgggaga gatgggtcaa accaaccgag acccaggaaa
2521 cgagtgaatc cgaaaaggaa gtggcccaag gcagatggga gattgagccc aaggacacag
2581 aaccagaagg taagaagggt aagaacaaga aaggaagagg caagaaacac acagctttct
2641 ccagtaaagg tctgagtgat gaggagtatg acgagttcaa gagaatcaga gaagaaagga
2701 acggaaaata ctccattgag gaatacctgc aagaccggga tcgctactat gaggaagtgg
2761 cagttgcccg ggcgacagag gaggacttct gtgaagagga ggaggccaag ataagacaaa
2821 gaatctttcg ccccacaaag aaacagagga aggaagaaag gggggtgctt ggtttggtta
2881 ctggctcaga catcaggaag agaagaccag acgattttca accgaagggc aacctgtggg
2941 cagacgacac caggagtgtg gactacaacg agagacttga tttcgaggct cccccgagtg
3001 tctggtcaag aatagtccca ttgggcactg gctggggctt ctgggtctca tcaaacctcc
3061 tgatcacaac aacgcacgtc ctacctaagg ggattaatga gctctttgga gttgagatca
3121 aacagattca gattcacaag tctggagagt tctgcaggtt cagattccca agaccaatca
3181 gaccagatgt cacagggctc gtgttggagg agggcgctcc agaaggcact gtctgctcca
3241 tactcgtgaa gagacctaca ggtgagatga tccccctggc agtgaggatg ggcacgcatg
3301 catccatgaa aatacagggt aggaccgtcg gtggccagat ggggatgctc ctcacagggg
3361 caaatgcgaa gaacatggac cttggcaccg gtcctggtga ctgcggttgc ccctacatct
3421 acaaacgtgg caatgatata gttgtcgcgg gtgtccacac cgcagcagcc cggggaggca
3481 acactgtcat atgtgccact caagggcaag atggggaagc agtccttgag ggaaatgaga
3541 accttggcac ttactgcggt gctccaatct tgggtccagg caaggcgccc aaacttagca
3601 cgaagaccaa gttctggcgt tcatcaccag acgctttgcc gccaggcact tatgaacctg
3661 cctacttggg aggtaaggac cctagagtgg aaaaaggacc atccctgcag caagtcatga
3721 gggaccagct aaaacctttc acagaaccca ggggcaagcc acctagacct gcagtcttag
3781 aagaagccaa aaagacagtg atgaatgttc tagagcaaac cattgaccct gctaaaccgt
3841 ggacctattc ccaagcatgt gcctcactgg acaagaccac ttccagtggt agcccccatc
3901 atgtcaggaa aaatgaccat tggaatgggg agtccttcac tggccccctc gcagaccaag
3961 catccaaagc caacctcatg tacgagcagg ccaaacatgt gcagcccgtg tacacggccg
4021 cactcaaaga tgaactagtc aaaactgata agatctacaa gaagataaag aaaaggctct
4081 tatgggggtc ggatcttggt acaatgatca ggtgtgccag ggcctttggc ggtctcatgg
4141 atagcatgaa ggcaagctgc atagctctcc catgtagggt aggaatgaac atgaatgaag
4201 atggccccat catatttgac aagcattcta agtataggta ccattatgat gctgactatt
4261 ccaggtggga ctcaacccag caaaggagca ttctctcggc cgctatggaa gtgatggtgc
4321 ggttctctgc tgaaccagag ctggcacaag tggttgcaga ggacctcctg gcacccagcc
4381 aactagatgt tggcgatttc gtcatctcag tccaggaggg tctgccatca ggggtcccat
4441 gcacatcaca atggaattca atagcacact ggatcctaac cttgagtgca atggcagaag
4501 tgtcgggtct ctcaccagat gttgttcaag cccactcctg tttctcattc tacggtgatg
4561 atgagatcgt cagcactgac atcaaccttg atcccatgaa gttgacacag aagctcagag
4621 agtatggcct ggtccccacc cgacctgaca aaactgaggg tcccctcgta ataactgaag
4681 atctcaccgg cctaacgttc ctgcgcaggt caattgcacg ggacccagct gggtggtttg
4741 gaaaattgga ccaagactca atcctcagac agttgtactg gacaaggggc cccaaccatg
4801 agaacccata tgagagcatg gtccctcatt cccagcgggc cacacaactt atggcccttc
4861 tcggtgaggc ttcactgcac ggtccccagt tttacaagaa agttagcaag atggttatta
4921 atgagatcaa aagtggtggt ctggaattct atgtgcccag acaagaggcc atgttcagat
4981 ggatgagatt ctctgacctc agcacatggg agggcgatcg caatcttgct cccgagggtg
5041 tgaatgaaga tggcgtcgaa tgacgctgct ccatcgaatg atggtgctgc caacctcgta
5101 ccagaggcca ccaatgaggt tatggcactt gagccggtgg tgggagcctc aattgctgct
5161 cctgtcgtcg gccaacaaaa tataattgac ccctggatta gagaaaactt tgttcaggca
5221 ccacagggtg agtttactgt ttcaccaagg aactcacctg gtgagatgct tctaaatctt
5281 gaattaggcc ctgagctcaa cccttatctg agtcacttgt cccgcatgta taacggctat
5341 gctggtggta tgcaggttca ggtggtccta gctgggaatg cgttcacagc tggtaaaatc
5401 atctttgccg ccgtcccacc acatttccct gttgagaaca ttagtgcagc ccaaatcaca
5461 atgtgccccc atgtaatcgt tgatgtaaga cagcttgagc cagtactttt gcccctccct
5521 gacataagga atagattctt tcattataac caggaaaata ccccccggat gagacttgtg
5581 gctatgttgt atacacccct tagagcaaat tctggtgagg atgtgtttac ggtgtcttgc
5641 agagttctga cccgcccagc ccccgacttt gagttcacgt ttttggtgcc accaactgtg
5701 gagtcaaaga ctaagccctt tacactccct attctgactc ttggagagct gtccaactcc
5761 agattccccg ctccgataga catgttgtac actgacccca atgaggcaat tgtggtgcaa
5821 ccacaaaatg gtaggtgcac tctagatgga acacttcaag ggaccaccca attggtaccc
5881 acccaaattt gctccttcag gggcacgcta attagccaga cgtcgaggtc tgcagattca
5941 acagattcag ccccacgggc gaggaaccac cctctccacg ttcagctgaa gaacctcgat
6001 gggacaccat atgacccaac agatgaggtg ccagcagttt tgggtgccat agatttcaaa
6061 ggaactgtgt ttggggtcgc tagccagaga aacaccacag ggaaccctac aggagcaacc
6121 cgcgcccatg aagtgcacat agacaccaca aaccctagat acaccccaaa gcttggctct
6181 gtgttgatgt attctgaatc tactgatttt gatgatggac aacccacccg ctttaccccc
6241 attggtatgg gagccgatga ttggcaccaa tgggaattgc ccaaatattc tggtcacctc
6301 actcttaaca tgaatttggc ccccgcagtt gcccctgctt tccctggtga gcgcattctc
6361 ttcttcagat cagtggtacc gtctgctggt ggctatggat caggtcacat agattgcctc
6421 atcccacagg agtgggttca gcatttctac caggaggccg ctccatcaca gtccgcggtg
6481 gctcttatca gatatgtcaa ccctgacact ggaagaaaca tctttgaggc aaaactgcat
6541 agagaagggt tcatcaccgt ggcaaattct ggaaacaacc ccatagttgt gcccccaaat
6601 ggttacttca ggtttgaggc ctgggtcaat caattctaca cactcacccc catgggaact
6661 ggacaggggc gcagaagagt tcaataatgg caggagcttt cttggctgga ttggcaggtg
6721 acgccataac aagtggtgtc gggtccctaa tcaatgctgg ggccaatgca attaaccaga
6781 aggtagaata tgactttaat aaacagctcc aattggcatc ctttaaacat gacaaagaga
6841 tgttgcaatc acaagtactg gccactaaac agctccagca ggagatgatg aacataaggc
6901 aaggggtctt gtccgctggc ggcttttccc ctacagatgc cgcgagaggt gctgtgaacg
6961 cgccgatgac aaaaattttg gattggaatg gaacaaggta ctttgcccca aatagtatga
7021 agacaaccag ttattcgggc cagttttcca gcaaccctgt gcataggcaa cccactttac
7081 cccgttctga acccccaaaa attaaggtta atagtgattc tgctagtgtg tatagttctg
7141 catctactgc tccttcacaa tcaactcact caacggcttt gactgcgggg tctagctcat
7201 ctaggacaac gtcctcttct gcagtagctt ccaccctatc taggactggt gactgggtga
7261 gaggacaaaa tgaaaggctt agcccgttta tggatggtgc tctccaaaca acttttgtca
7321 caccaccatc gagcaaagct tcatcatatg ggtcggtctc aaccgttccc aaagctgttt
7381 tggactcctg gactcctatg ttcaataccc ataggcagcc tctcttcgct catgtgcgca
7441 ggcgagggga gtcacagatt tagtgaaaag attgattagg ttttctttct ttcttctttt
7501 ccttttcttt ctttt
//