Typing tool
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Typing tool
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Complete norovirus genomes
| MW305598 | GII.6 | |
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| GII.P6 |
ORF1: 1..5063
ORF2: 5044..6687
ORF3: 6687..7463
LOCUS MW305598 7510 bp RNA linear VRL 06-JUL-2021
DEFINITION Norovirus GII isolate 212 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MW305598
VERSION MW305598.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7510)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses reveal coexistence of
viral populations evolving under recombination constraints
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7510)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7510
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="212"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Japan"
/collection_date="16-Feb-1996"
/note="genotype: GII.6[GII.P6]"
gene <1..5063
/gene="ORF1"
CDS <1..5063
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QPJ59130.1"
/translation="FGSQNSVNDSINTTPSNKEEVGAFSNIKVGLKKMLGAVPKNTKT
PSGDQHCPTVKIGSKTLVIPPEPPNGEDIVQFDAKSETVRGLPDLTTVQNEHENTPYT
VPPLSEREHRPAAEPLPGTILEMWDGEFYHYSIYVSGGKALGVHKPPAAISLATVELT
PISLYWRPVYTPNYLVHPDTLKGLAGEKFPYTAFSNNCYNFCCWVLELNDTWLCRRSI
SRTTGFFKPYQSWNRKPLPTIDDGKIKKVANAILCALGSLFSKPIKDLLGKLKPLNLL
HLLASCDWTFAGIVETVILMAELFNVFWTPPDVSNFIASLIGDFQLQGPEDLAVELVP
VVMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVVKWFFPKKEEKAE
METLRAIEDAVLDMEAIGNNHLTTLLKDKDSLTAFMKTLDLEEEKARKLSTKSSSPDI
VGTINAILARIAAARSLLHKAKEEMFSRIRPVVVMISGRPGIGKTHMARHLAKNIANT
MSGDQRVGLVPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALTLQELADTCPVTLNCD
RIENKGKMFDSDVIIITTNLVNPAPLDYVNFEACSRRIDFLVYAESPEIEKVKRDFPG
QPDMWKDHFKPDFSHIKLTLAPQGGFDKNGNTPHGKGTMRSLTQGSLTARVAGLVHER
RDEFQLQGGSLQTYNFDTNRVSAFRKLAADNKYGIMETMRVGAALKNVKTLEDLRVAL
RDVKFNECEIIYRNTKYRVSSDGKGTVSVNKVEDLTSQTANEVSSALLRLRQARARYY
VSCFQDLVYTLIQVAGASFVVNRISKRFCWERWVKPTETQETSEPEKETAQNKWEIEP
KDTEPEGKKGKNKKGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRDR
YYEEVAVARATEEDFCEEEEAKIRQRIFRPTRKQRKEERGVLGLVTGTDIRKRRPDDF
QPKGNLWADDTRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSNLLITTTHVLPKG
VKELFGVDVKQIQIHKSGEFCRFRFPKPIRPDVSGLVLEEGAPEGTVCSILVKRPTGE
MIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDCGCPYIYKRGNDI
VVAGVHTAAARGGNTVICATQGQDGEAVLEGNESLGTYCGAPILGPGKAPKLSTKTKF
WRSSPDALPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEPRGKPPRPTVLEEA
KKTVMNVLEQTIDPAKPWTYSQACASLDKTTSSGSPHHIRKNDHWNGESFTGPLADQA
SKANLMYEQAKHMQPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGTMVRCARAFGGL
MDSMKASCIALPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDSTQQRSILSAAME
VMVRFSAEPELAQVVAEDLLAPSQLDVGDFVISVQEGLPSGVPCTSQWNSIAHWILTL
SAMAEVSGLSPDVVQAHSCFSFYGDDEIVSTDINLDPSKLTQKLREYGLVPTRPDKTE
GPLVITEDLTGLTFLRRSIARDPAGWFGKLDQDSILRQLYWTRGPNHENPYESMVPHS
QRATQLMALLGEASLHGPQFYKKVSKMVISEIKSGGLEFYVPRQEAMFRWMRFSDLST
WEGDRNLAPESVNEDGVE"
mat_peptide <1..971
/gene="ORF1"
/product="p48"
mat_peptide 972..2069
/gene="ORF1"
/product="NTPase"
mat_peptide 2070..2588
/gene="ORF1"
/product="p22"
mat_peptide 2589..2987
/gene="ORF1"
/product="VPg"
mat_peptide 2988..3530
/gene="ORF1"
/product="Pro"
mat_peptide 3531..5060
/gene="ORF1"
/product="RdRp"
gene 5044..6687
/gene="ORF2"
CDS 5044..6687
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ59131.1"
/translation="MKMASNDAAPSNDGAANLVPEANNEVMALEPVVGASIAAPVVGQ
QNIIDPWIRENFVQAPQGEFTVSPRNSPGEMLLNLELGPELNPYLSHLSRMYNGYAGG
MQVQVVLAGNAFTAGKIIFAAVPPHFPVENISAAQITMCPHVIVDVRQLEPVLLPLPD
IRNRFFHYNQEDTPRMRLVAMLYTPLRANSGEDVFTVSCRVLTRPAPDFEFTFLVPPT
VESKTKPFTLPILTLGELSNSRFPAPIDMLYTDPNETIVVQPQNGRCTLDGTLQGTTQ
LVPTQICSFRGTLISQTSRSADSTDSAPRVRNHPLHVQLKNLDGTPYDPTDEVPAVLG
AIDFKGTVFGVASQRNTTGSSVGATRAHEVHIDTTNPRYTPKLGSVLMYSESSDFDDG
QPTRFTPIGMGADDWRQWELPEYSGHLTLNMNLAPAVAPAFPGERILFFRSVVPSAGG
YGSGQIDCLIPQEWVQHFYQEAAPSQSAVALIRYVNPDTGRNIFEAKLHREGFITVAN
SGNNPIVVPPNGYFRFEAWVNQFYTLTPMGTGQGRRRAQ"
gene 6687..7463
/gene="ORF3"
CDS 6687..7463
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ59132.1"
/translation="MAGAFFAGLAGDAITNGVGSLINAGANAINQKVEYDFNKQLQLA
SFKHDKEMLQSQVLATKQLQQEMMNIRQGVLTAGGFSPTDAARGAVNAPMTKILDWNG
TRYFAPNSMKTTSYSGQFSSNPVHRQPTLSRSDPPKVKINSDPASVYSSTSTAPSQST
HSTTLTAGSGSSRTSSSSAATSTLSRTSDWVRGQNERLSPFMDGALQTTFVTPPSSRA
SSNGSVSTVPKAVLDSWTPMFNTHRQPLFAHLRRRGESQI"
ORIGIN
1 cctttggcag tcaaaactct gtcaatgaca gtatcaacac caccccttcc aataaagaag
61 aggttggtgc attctccaac atcaaagttg gacttaagaa aatgctgggt gccgtgccta
121 aaaacaccaa aacacccagc ggtgaccagc actgccccac agttaagatc gggtccaaaa
181 cactagtgat cccaccagaa cccccaaacg gcgaggacat tgtgcagttc gacgcaaaat
241 cggaaactgt acgtgggctg cccgacctga cgacagtgca aaatgaacat gagaacaccc
301 catacacagt ccctccactg agtgaaaggg aacacaggcc agccgctgag ccactccccg
361 gcacaatact ggagatgtgg gatggtgagt tctaccatta ctccatctac gtcagcggag
421 gcaaagctct gggggtacac aaacccccag cggctataag cctcgcgaca gtggagctca
481 ctcccatatc cctttactgg cggcctgtct acactccaaa ctacctggtc cacccagaca
541 cactgaaggg tcttgctggt gaaaagtttc cctacacggc ctttagtaac aactgctaca
601 atttctgttg ttgggtactt gaacttaacg acacgtggct ttgcagaagg agtatttcta
661 gaaccactgg cttctttaaa ccatatcagt cttggaacag gaagcccctc cccaccattg
721 atgatgggaa gatcaaaaag gtggccaatg caattctctg cgcacttggc tcactgtttt
781 caaaaccaat caaagaccta ctgggtaaac tcaagccact taacctacta catctgcttg
841 cgtcatgtga ctggacgttt gcgggtatag tagagacagt catcttaatg gcggaactct
901 tcaatgtatt ctggacccca cctgatgttt ccaatttcat agcctccttg ataggtgatt
961 ttcagttaca aggacccgag gacttggctg tggagctcgt ccccgtggtt atgggaggca
1021 taggtatggt cctcggtttc actgccgaga agattggccg catgttgtca tctgccgcgt
1081 caaccctaag ggcatgtaaa gatctgggga actacgccct agacatacta aaactagtcg
1141 tgaagtggtt ctttccaaag aaagaagaga aggccgaaat ggagacctta agggcgattg
1201 aggatgccgt cttagacatg gaggcaatag ggaacaatca cctcacgaca cttctcaagg
1261 acaaggatag ccttactgca tttatgaaaa ccctagatct agaggaggag aaagcaagaa
1321 agctatcgac gaagtcatcc tcaccagaca tcgtcggcac cattaacgcc atactggcta
1381 gaatagcagc cgctaggtcc ctcctacaca aggccaagga agagatgttt agcagaatta
1441 gaccagtagt tgtcatgatc tcaggtagac ctggcattgg caaaacccac atggcaaggc
1501 atctggctaa gaatatagcc aacacaatga gtggagacca gagagttgga cttgtcccgc
1561 gcaacggggt tgaccattgg gatgcttaca ggggggagag agtggtcctg tgggacgact
1621 atggtatggg gaaccctgtc aaagatgcct taacactgca agaactggcc gacacctgtc
1681 cagtcacctt gaattgtgat aggattgaga ataaggggaa gatgtttgac agtgatgtca
1741 tcataatcac aaccaacttg gtcaaccctg cacctctcga ttatgtgaac ttcgaggctt
1801 gctccagaag gatcgatttc cttgtctatg cagagtcacc agaaatagaa aaggtcaaga
1861 gagacttccc tggtcagcct gatatgtgga aagatcactt caaaccggac ttttcccaca
1921 taaagctgac tttggccccc cagggcgggt ttgacaagaa tggcaacacc ccacatggta
1981 aaggtaccat gcgttctctg acccaggggt ctctgactgc aagagtggcg ggtcttgttc
2041 acgagaggag agatgaattc cagctgcaag ggggtagcct acaaacatac aattttgata
2101 ccaacagggt ctctgcgttt aggaaactgg ccgcagacaa caagtatgga atcatggaga
2161 caatgagagt aggtgcggca ctcaagaatg tcaagacttt ggaagacctc agagttgctt
2221 tgagagatgt aaaattcaat gaatgtgaga tcatctacag gaacaccaag taccgggtct
2281 catctgatgg caaaggcaca gtctctgtta acaaagtcga ggacctcact tcccagactg
2341 caaacgaggt gagttcagcc ctcctcaggc tcagacaagc gagggccaga tattatgtca
2401 gctgcttcca ggaccttgtc tacactctca tacaggttgc tggggcttca tttgtcgtta
2461 acaggatctc caagaggttc tgctgggaaa gatgggttaa accgaccgag acccaggaga
2521 cgagtgagcc cgagaaggaa actgcccaga ataaatggga gattgaaccc aaggacacag
2581 aaccagaagg taagaagggt aaaaacaaga aaggaagggg caagaaacac acagccttct
2641 ccagtaaagg cctgagtgat gaagagtatg atgagtacaa aaggattagg gaagaaagaa
2701 atggaaagta ctccattgag gaataccttc aagaccgtga ccgctactac gaagaagtag
2761 cagttgcccg agcaacagag gaggacttct gtgaagagga agaggccaaa ataaggcaaa
2821 gaatcttccg cccgacaagg aagcaaagaa aagaggaaag gggtgtgctt ggtctggtta
2881 ctggcacgga tattaggaag agaagaccag atgacttcca accaaagggc aatttgtggg
2941 cagatgacac taggagtgtg gactacaatg agagacttga tttcgaggcc cccccaagcg
3001 tgtggtcaag gatagtccca ctgggcaccg gctggggctt ctgggtctca tccaacctcc
3061 taattacaac aacacatgtc ctgcctaagg gtgttaagga actctttggt gtcgacgtca
3121 aacaaatcca aatccacaaa tctggagaat tttgcaggtt tagattccca aaaccaatca
3181 gaccagacgt ctcagggctt gtattggaag aaggtgcacc agagggcact gtttgctcca
3241 tactcgtgaa gagaccaaca ggtgagatga tccccctagc ggtgaggatg ggcacgcatg
3301 catctatgaa aatccagggc aggactgttg gtggccaaat gggaatgctc ctcactgggg
3361 cgaacgcaaa gaacatggac cttggcaccg gcccggggga ttgcggttgc ccatacattt
3421 acaagcgcgg caatgacata gtcgtggcag gtgtccacac tgcagcggcc cgaggaggca
3481 acactgtcat ctgtgccacc caagggcagg acggggaagc agttcttgaa gggaatgaga
3541 gccttggcac ttactgtggt gccccaatcc taggtcctgg caaggcgccc aagctcagca
3601 cgaagaccaa gttctggcgc tcatcgcctg atgccctacc acccggcaca tatgaacctg
3661 cctacctagg aggcaaggac cccagagtag agaagggacc ttccctgcag caagttatga
3721 gggatcagtt gaaacctttc acggaaccca ggggcaaacc accaagaccc acagtcctgg
3781 aagaagctaa aaagacagta atgaacgtcc tggaacagac cattgacccc gctaaaccgt
3841 ggacatactc acaagcatgt gcttccttgg ataagactac ttccagtggc agcccccatc
3901 acatcaggaa gaatgaccat tggaacggag agtcttttac aggccccctc gcagaccaag
3961 catccaaagc taatctcatg tatgagcagg ccaaacacat gcagcctgtg tacacagctg
4021 cactcaagga tgagctcgtc aaaactgaca aaatttacaa gaagataaag aagaggctcc
4081 tatgggggtc ggaccttggt acaatggtca ggtgtgccag ggcctttggt ggtctcatgg
4141 acagcatgaa agcaagttgc atagccctcc cgtgcagagt gggaatgaac atgaatgagg
4201 acgggcctat catttttgac aagcactcca aatacagata ccattatgac gctgactact
4261 ctaggtggga ctcaactcaa caaagaagca tcttgtccgc cgctatggaa gtgatggtgc
4321 ggttctctgc agaaccagaa ttggcacaag tggttgcaga ggacctcttg gcacccagcc
4381 agctggacgt tggcgacttt gtcatctcag ttcaggaagg cctaccatca ggagtcccat
4441 gcacgtcaca atggaattca atagcccact ggatcttgac tttgagtgca atggcagaag
4501 tgtcaggcct ctcgccagat gttgtgcaag cccattcctg tttctctttc tatggtgatg
4561 atgagattgt gagcactgac atcaaccttg acccttcaaa actgacacag aaactcaggg
4621 agtatggtct ggtccccacc cgacctgaca aaactgaagg cccccttgtc ataactgagg
4681 acctcaccgg cctaacattc ctgcgcaggt cgatcgcgcg ggatcccgct gggtggtttg
4741 gaaagctgga tcaagactca attctcagac agttgtattg gacaagaggg cccaaccatg
4801 agaacccata cgaaagcatg gtcccccact cccagcgagc cacacaactc atggcccttc
4861 ttggtgaagc ttcactgcac ggaccccaat tctacaagaa ggtcagtaag atggttatca
4921 gtgagatcaa gagtggtggt ctggagtttt atgtgcccag acaagaggcc atgtttaggt
4981 ggatgagatt ctctgacctc agcacatggg agggcgatcg caatcttgct cccgagagtg
5041 tgaatgaaga tggcgtcgaa tgacgctgct ccatcgaatg atggtgctgc caacctcgta
5101 ccagaggcca acaatgaggt tatggcactt gaaccggtgg tgggagcctc aattgcagct
5161 cctgtcgtcg gtcaacaaaa tataattgac ccctggatta gagaaaattt tgttcaggca
5221 ccacagggtg agtttactgt ttcaccaaga aactcgcctg gtgagatgct tttaaatctt
5281 gaattaggcc cagagctcaa tccttacctg agtcatttat cccgcatgta taatggttat
5341 gctggtggca tgcaggttca ggtggtccta gctgggaatg cgttcacagc tggtaaaatc
5401 atctttgccg ccgttccacc acatttccct gtagagaata ttagtgcagc tcaaatcaca
5461 atgtgccccc atgtgattgt tgatgtgaga cagcttgagc ctgtgctttt gcccctccct
5521 gatataagga atagattctt tcactacaac caggaagaca ccccccggat gagacttgtg
5581 gctatgttgt acacacctct tagagcaaac tctggtgagg acgtgttcac agtgtcttgc
5641 agggtcttga cccgcccagc ccctgacttt gagttcacgt tcttagtgcc accaaccgta
5701 gaatcaaaga ccaagccttt cacactccct attttaaccc taggggaact atccaattcc
5761 agattccctg ctccaataga catgctgtac acagatccca atgagacaat tgtggtacaa
5821 ccacaaaatg gcagatgcac cctagatggg acactccaag ggaccaccca gctggtgccc
5881 acccaaattt gctcttttag gggcacgtta atcagccaaa cgtcgaggtc tgcagattca
5941 acagattcag ctccacgagt gaggaaccac cccctccacg ttcagctgaa gaacctcgac
6001 ggtacaccat atgacccaac agatgaggtg ccggcagttc tgggtgccat agatttcaaa
6061 ggaactgtgt ttggagttgc tagccagaga aacaccacgg ggagctctgt aggggcgacc
6121 cgcgcccacg aggtgcacat agacaccaca aaccctagat acaccccaaa acttggttct
6181 gtgttgatgt attctgagtc tagtgatttt gatgatggac aaccgactcg cttcaccccc
6241 attggcatgg gagcagatga ttggcgccaa tgggaattgc ccgaatattc cggtcacctc
6301 actcttaaca tgaacctagc ccccgcagtt gcccctgctt tccccggtga gcgcatcctc
6361 ttcttcaggt cagtggttcc atctgctggt ggttacggat caggccaaat agactgcctc
6421 atcccacagg aatgggtcca gcacttctac caggaggccg ccccatcaca atctgcggtg
6481 gctcttatca gatatgttaa ccctgacact gggagaaaca tctttgaggc aaagctacat
6541 agagaagggt tcatcactgt ggcaaattct ggaaacaacc ccatagttgt gcccccaaat
6601 ggttatttca ggtttgaggc ctgggtcaat caattttaca cactcacccc catgggaact
6661 ggacaggggc gtaggagagc ccaataatgg caggagcttt ctttgctgga ttagcaggtg
6721 acgccataac aaatggtgtc gggtccctga tcaatgctgg ggccaatgca attaaccaga
6781 aggtagagta tgatttcaac aaacaactcc aattggcatc ctttaaacat gacaaggaaa
6841 tgttgcaatc acaagttctg gccaccaaac agctccagca agaaatgatg aacataaggc
6901 aaggggtctt gaccgctggc ggcttttccc ctacagatgc cgcgagaggc gctgtaaacg
6961 cgccaatgac aaaaattctg gattggaatg gcacaagata ttttgctcca aatagtatga
7021 aaacaaccag ttattcgggt cagttctcca gtaatcctgt gcataggcaa cccactttgt
7081 cccgttctga tcccccaaaa gttaagatta atagtgatcc tgctagtgta tatagttcta
7141 catccactgc tccttcacaa tcaacccatt caacgactct gactgcaggg tctggatcat
7201 ccaggacatc ctcctcttcc gcagcaactt ccaccctatc taggaccagt gactgggtga
7261 ggggacaaaa tgagaggctt agcccgttca tggatggtgc tctccaaaca acttttgtca
7321 caccaccatc gagcagagct tcatcaaatg ggtcggtctc aaccgttccc aaagctgttt
7381 tggactcctg gactcctatg tttaacaccc ataggcagcc tctcttcgca cacttacgta
7441 ggcgagggga gtcacaaatt tagtgaaaag attgattagg ttttcttctc ccttctttct
7501 ccttttcttt
//