Typing tool
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Typing tool
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Complete norovirus genomes
| MW305584 | GII.2 | |
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| GII.P30 |
ORF1: 1..5069
ORF2: 5050..6678
ORF3: 6678..7454
LOCUS MW305584 7494 bp RNA linear VRL 06-JUL-2021
DEFINITION Norovirus GII isolate T045 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MW305584
VERSION MW305584.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7494)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses reveal coexistence of
viral populations evolving under recombination constraints
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7494)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7494
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="T045"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Tunisia"
/collection_date="15-Jul-1977"
/note="genotype: GII.2[GII.P30]"
gene <1..5069
/gene="ORF1"
CDS <1..5069
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QPJ59088.1"
/translation="AAVNSNNDNAKSSSDGVLSSMAVTFKRALGARPKQPPPREIPQR
PPRPPTPELVKKIPPPPPNGEDEPVVHYSAKDGITGLPELTTVRQPEEAATAFSVPPL
DQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAISLAKVELTPLSL
YWRPVYTPQYLIAPDTLRRLHGESFPYTAFDNNCYAFCCWVLELNDSWLSRRMIQRTT
GFFRPYQEWNRKPLPTMDDSKLKKVANIVLCALSSLFTRPIKDIIGKLRPLNILNILA
SCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAVELVPIVMG
GIGLVLGFTKERIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKEEANELAMV
RAIEDAVLDLEAIENNHMTALLKDKDSLATYMRTLDLEEEKARKLSTKSASPDIVGTI
NALLARIAAARSLVHRAKEELSSRLRPVVVMISGKPGIGKTHLARELAKKIATTLSGD
QRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPVHDALRLQELADTCPLTLNCDRIEN
KGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDVEKAKRDFPGQPDM
WKSAYSSDFSHIKLMLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGLLHERLDEF
ELQGPNLTTFNFDRNKIQAFRQLAAENKYGLVDTMRVGGQLKGVRTMPELKQALKNIS
IKRCQIVYGGSTYTLESDGKGNVKVEKVQNTNVQINNELTGALHHLRCARIRYYVKCV
QEALYSIIQIAGAAFVTTRIVKRMNIQNLWSRPPVGDAEEVAGQDSCPKPKGDEEFVI
SSSDITPEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDR
DKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLVTGSEIRKRNPD
DFKPKGKLWADDERVVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSPSLFITSTHVIP
QGTQEFFGVPIKQIQIHKSGEFCRLRFPKSIRTDVTGMILEEGAPEGTVVSLLIKRPT
GELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGN
DYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGNAPKLSTKT
KFWRSSTVPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGKPPKPSVLE
AAKKTIINVLEQTIDPPQKWSFSQACASLDKTTSSGHPYHIRKNDCWNGESFTGKLAD
QASKANLMYEEGKNMTPVYTGALKDELVKTDKIYGQIKKRLLWGSDLATMVRCARAFG
GLMDELKAHCVTLPVRVGMNMNEDGPIIFERHSRFSYHYDADYSRWDSTQQRAVLAAA
LEIMVKFSPEPHLAQIVAEDLLAPSVMDVGDFKITINEGLPSGVPCTSQWNSIAHWLL
TLCALSEVTNLAPDITQANSLFSFYGDDEIVSTDIKLDPEKLTAKLKEYGLKPTRPDK
TEGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQGSILRQIYWTRGPNHEDPSETMIP
HSQRPIQLMSLLGEAALHGPTFYTKISKLVITELKEGGMDFYVPRQEPMFRWMRFSDL
STWEGDRNLAPSFVNEDGVE"
mat_peptide <1..959
/gene="ORF1"
/product="p48"
mat_peptide 960..2057
/gene="ORF1"
/product="NTPase"
mat_peptide 2058..2594
/gene="ORF1"
/product="p22"
mat_peptide 2595..2993
/gene="ORF1"
/product="VPg"
mat_peptide 2994..3536
/gene="ORF1"
/product="Pro"
mat_peptide 3537..5066
/gene="ORF1"
/product="RdRp"
gene 5050..6678
/gene="ORF2"
CDS 5050..6678
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ59089.1"
/translation="MKMASNDAAPSTDGAAGLVPESNNEVMALEPVAGAALAAPVTGQ
TNIIDPWIRANFVQAPNGEFTVSPRNAPGEVLLNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKLVFAAVPPHFPVENLSPQQITMFPHVIIDVRTLEPVLLPLPD
VRNNFFHYNQKDDPKMRIVAMLYTPLRSNGSGDDVFTVSCRVLTRPSPDFDFTYLVPP
TVESKTKPFTIPILTLGELSNSRFPVSIDQMFTSPNEVISVQCQNGRCTLDGELQGTT
QLQVSGICAFRGEVTAHLHDNDHLYNVTITNLNGSPFDPSEDIPAPLGVPDFQGRVFG
VISQRDNYNASGHNQPANRGHDAVVPTYTAQYTPKLGQIQIGTWQTDDLTVNQPVKFT
PVGLNDMEQFNQWVVPRYAGALNLNTNLAPSVAPVFPGERLLFFRSYLPLKGGYGNPA
IDCLLPQEWIQHFYQEAAPSMSEVALVRYINPDTGRALFEAKLHRAGFMTVSSNTSAP
VVVPANGYFRFDSWVNQFYSLAPMGTGNGRRRIQ"
gene 6678..7454
/gene="ORF3"
CDS 6678..7454
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ59090.1"
/translation="MAGAFIAGLAGDVLSNGLGSLINAGANAINQRAEFDFNQKLQQN
SFNHDKEMLQAQIQATKQLQADMMAIKQGVLTAGGFSPADAARGAVNAPMTQALDWNG
TRYWAPGSMRTTSYSGRFTSAAPTRQADFQHTQGRPSSGSSVSSYSTQSSRPTLTTTT
GSSHSTTSSNLTRSTNLPSTTSRATSRTSEWVREQNRNLEPYMHGALQTAFVTPPSSR
ASDGTVSTVPKGVLDSWTPAFNTRRQPLFAHLRKRGESQV"
ORIGIN
1 ccgctgctgt caacagcaac aacgacaacg caaaatcttc aagtgacgga gtactatcta
61 gtatggctgt cacttttaaa cgagccctcg gggcccggcc taaacagccg cccccgaggg
121 aaataccaca aaggcctcca aggccaccca ccccagaatt ggtgaaaaag atcccacctc
181 ccccgcctaa cggggaggac gaaccggtcg ttcactatag tgctaaagat ggtataactg
241 ggctgcccga acttacaaca gtgaggcagc cagaagaggc cgctacagca ttcagcgtcc
301 cacccctcga ccagagagag aacagggacg ctaaagaacc attgaccggc accatcttgg
361 agatgtggga tggcgagatc taccattatg gcctatatgt ggagcgaggg ctggtgcttg
421 gcgtgcacaa accaccagcc gccatcagcc tcgctaaagt tgagttaaca cctctatctt
481 tgtattggag gccagtgtac actcctcagt acctcatcgc tcctgacacc ctcaggagac
541 tgcacgggga gtcatttcca tacacggcct ttgataacaa ctgctatgcc ttctgctgct
601 gggtgttaga actaaacgac tcttggttga gcagaaggat gatacaaaga acaactggct
661 ttttcagacc ttaccaggaa tggaatagga agcccctccc taccatggat gattccaagt
721 tgaagaaggt ggccaacata gtcttgtgtg ccttgtcatc actattcact agacccatca
781 aggacataat tgggaaactc aggcctctca acattcttaa catcctggct tcttgtgatt
841 ggactttcgc aggtatagtg gagtctctaa ttctcctagc tgaactcttc ggagttttct
901 ggacaccccc agatgtgtct gcgatgatcg cccccttact gggtgactac gagctgcaag
961 gacccgaaga tcttgctgtg gaacttgtac caatagtgat gggggggata ggattggtgt
1021 tggggttcac caaggaaaga attgggaaga tgctatcatc tgctgcttcc accctgaggg
1081 cctgcaaaga ccttggcgct tatggactgg aaattctgaa actggtcatg aaatggtttt
1141 tcccaaagaa agaagaggca aacgagcttg cgatggtgag ggctattgag gacgcagtcc
1201 tagatctcga ggctattgag aacaaccata tgacagctct actcaaagac aaagatagcc
1261 tcgcgacata catgaggact cttgatttgg aggaagaaaa ggccagaaag ctctccacca
1321 agtccgcttc acctgatata gtgggcacga tcaacgccct actggctaga atcgccgctg
1381 ctcgttccct tgtgcacagg gccaaggaag aactgtccag caggctaagg ccagttgttg
1441 tgatgatatc tggtaagcca ggcatcggga agacccatct ggctagagaa ttggcaaaga
1501 agatcgctac aaccctatca ggagaccaga gggtaggcct catcccccgc aacggggtcg
1561 atcactggga tgcttacaag ggtgagagag tcgtcctctg ggacgattat gggatgagta
1621 accctgtcca tgatgcccta agactccaag aacttgctga cacctgcccc ttgaccctaa
1681 actgtgacag gattgagaat aagggcaagg tctttgacag tgatgccata atcatcacaa
1741 ccaacctggc caacccagct ccacttgatt atgtcaactt tgaagcttgc tccaggcgca
1801 ttgacttcct tgtgtatgcc gatgcacctg acgttgagaa agcaaagcgc gacttcccgg
1861 gacaacctga catgtggaag agcgcttaca gctccgactt ctcacacatc aagctaatgc
1921 tggctcccca gggtggtttt gacaaaaatg gcaacacccc acacggaaaa ggtgtcatga
1981 agaccctcac aacaggctcc ctcattgccc gtgcttcagg gctcctccat gaaagattgg
2041 atgagttcga gctacaagga cccaacctca caactttcaa ttttgaccgt aataaaatac
2101 aggctttcag gcagcttgcc gctgaaaaca aatatggcct ggtggacaca atgagagtgg
2161 gtggacaact caagggtgtc agaactatgc cagaactcaa gcaggccctc aagaacatat
2221 caatcaaaag gtgccagata gtgtatggtg gcagcaccta tacacttgaa tctgatggca
2281 aagggaatgt gaaagtggaa aaagtacaaa ataccaatgt ccaaatcaac aacgagctaa
2341 ctggtgcttt acaccatctc cggtgcgcca ggatcaggta ctatgttaaa tgtgttcagg
2401 aggctcttta ttccatcatc caaattgctg gggccgcttt tgtaaccacg cgcattgtga
2461 agcgcatgaa catacaaaac ttgtggtcaa ggccaccagt aggagatgcg gaggaggttg
2521 ctggccagga tagttgccca aagcccaaag gtgatgagga gttcgtcatc tcgtctagtg
2581 acatcacacc tgaaggcaag aaaggaaaga acaagactgg ccgcggcaag aaacacacag
2641 ccttctcgag caagggtctt agtgatgagg aatatgatga gtacaaaaga atcagggaag
2701 aaaggaacgg taagtactcc atagaagaat accttcagga cagagacaag tattatgaag
2761 aagtggccat agccagggca actgaggaag acttctgtga ggaagaagaa gccaaaatcc
2821 gacagaggat atttaggcca acgaggaaac aacgcaagga ggagagggct tcccttggtc
2881 ttgtcactgg ctcagagatc aggaagagaa acccagacga cttcaaacct aaaggaaagc
2941 tgtgggctga tgatgaaagg gtcgtcgact ataatgagaa actcagtttt gaggcccccc
3001 cgagcatctg gtcaaggata gtcaactttg ggtcaggatg ggggttctgg gtgtccccca
3061 gcctgtttat tacatcaacc catgtcatac cccaaggcac tcaggaattc tttggtgtac
3121 ccatcaagca gattcaaatt cacaaatcag gggagttttg tcgcctgaga ttccctaaat
3181 caatcagaac tgatgtaaca ggcatgattc tagaagaggg ggccccagaa ggaaccgtgg
3241 tctcattact catcaagaga ccaaccggtg agctcatgcc tctggcagcc agaatgggca
3301 cccatgcgac tatgaagatc caaggtcgca cggttggagg tcagatgggt atgttgctaa
3361 cagggtccaa tgctaagagc atggatttgg gtacaacacc tggtgactgt ggctgcccct
3421 acatttacaa gagaggcaat gactacgtag tcatcggcgt gcacacagcc gctgctcgcg
3481 gaggtaacac tgtcatctgt gcaacccagg gtagtgaagg tgaggccacg ctcgaaggcg
3541 gtgacaacaa aggtacctac tgtggagctc caatactagg ccctggtaac gcacccaagc
3601 tcagcaccaa gaccaaattc tggaggtcct ccacagtgcc actcccaccc gggacctatg
3661 aaccagccta cttaggtggt aaggacccca gggtgaaagg tggaccttca ctgcaacaag
3721 tcatgagaga ccagctaaaa ccattcactg agcctagggg caaaccaccc aagccaagtg
3781 tgctggaagc cgccaagaag accatcatta atgtgttgga acaaacaata gatccccccc
3841 aaaaatggtc attttcacaa gcatgtgcgt cgcttgataa aaccacctcc agcggccacc
3901 cctaccacat acggaagaac gattgttgga atggggagtc tttcacagga aaattagcag
3961 atcaagcatc aaaagctaac ttaatgtatg aggaaggaaa gaacatgacc ccagtctaca
4021 caggggctct caaggatgaa ctggtcaaga ctgacaagat ctatggacag atcaagaaaa
4081 ggcttctttg gggctcggac ctggcaacga tggttcgttg tgctcgggcg tttggagggt
4141 tgatggatga gcttaaggcc cattgtgtaa cacttcctgt cagggttggg atgaacatga
4201 atgaggatgg acccataatc tttgaaagac actccaggtt ctcataccac tatgatgcag
4261 actactcacg ctgggactca acccaacaga gggcagtgct agctgcagcc ttggaaatca
4321 tggttaaatt ctcaccagaa ccacacttgg cccaaattgt tgcagaggac cttctagccc
4381 ctagtgtgat ggatgtaggt gatttcaaaa taacaattaa tgagggtcta ccctcgggag
4441 taccctgcac atcgcagtgg aattccatcg cccactggct tctcacactc tgtgcactat
4501 ctgaagttac aaacctggct cccgacatca cacaagctaa ctccttgttc tctttctatg
4561 gtgatgatga aattgtaagc actgacataa aattagaccc agagaaactc acagcaaaac
4621 tcaaagaata cggactcaaa ccaacccgcc cggacaaaac tgaaggaccc ctgatcatat
4681 ccgaggactt gaatggcttg acctttctgc ggaggaccgt aacccgcgat ccagctgggt
4741 ggtttggcaa gttagaccag ggttcaattc tcaggcagat atactggact aggggcccca
4801 accatgagga cccgtccgaa acaatgatac cacactccca gaggcctata cagctgatgt
4861 ctcttttggg tgaagcagcc ttgcatggtc caacatttta caccaaaatc agtaaattgg
4921 tcattacaga actgaaggaa ggtggcatgg atttttacgt gcccaggcag gaacccatgt
4981 tcaggtggat gagattctca gatttgagca cgtgggaggg cgatcgcaat ctggctccca
5041 gttttgtgaa tgaagatggc gtcgaatgac gccgctccat ctactgatgg tgcagccggc
5101 ctcgtgccag aaagtaacaa tgaggtcatg gctcttgagc ccgtggctgg cgctgcctta
5161 gcggctccag tcactggcca aacaaatatt atagaccctt ggattagagc aaattttgtc
5221 caggccccta atggtgaatt cactgtttcc ccacgcaatg cccctggtga agtgctacta
5281 aatctagaac tgggtccaga actgaaccct tatctggcac acttggcaag gatgtacaac
5341 gggtatgccg gtggaatgga ggtgcaggtc atgctagctg ggaatgcgtt tacggctgga
5401 aagttggtct tcgccgctgt tccacctcat ttcccggttg aaaaccttag cccgcagcaa
5461 attaccatgt ttccccatgt gattatagat gttaggactt tagaacctgt tttactacca
5521 cttcctgatg ttaggaataa cttcttccac tacaaccaga aagatgaccc taagatgaga
5581 attgtggcca tgctttacac cccccttaga tcgaatggtt ctggtgatga tgtgttcacg
5641 gtctcttgta gagtgttgac taggccttcc cctgattttg atttcacata cttagtgcca
5701 ccaacagtgg agtctaaaac aaaaccattc actatcccaa tcctcacact cggggagctt
5761 tccaattcta gatttccagt gtccatagat cagatgttca ctagccccaa tgaagtcata
5821 tctgtgcagt gtcagaatgg aaggtgtaca ctagacgggg agcttcaagg aacaacgcaa
5881 ctccaagtca gtggtatctg tgcatttaga ggagaagtga ctgcccactt gcatgataat
5941 gaccatcttt ataatgtcac cataacaaat ttaaacgggt ctccttttga cccctctgag
6001 gacatccctg ctcccctggg tgtgcccgac tttcaaggga gggtttttgg tgtcatcagt
6061 cagagagaca actacaatgc cagtggacat aaccagcctg caaacagggg acacgatgct
6121 gtggttccaa cctacacagc tcaatacacc ccaaaattgg gtcaaatcca gattggcacg
6181 tggcagactg atgacctaac agtcaatcag cctgttaaat tcaccccagt tggccttaat
6241 gatatggagc aatttaatca atgggtggtc cctaggtatg ctggtgcact aaatttaaac
6301 acaaaccttg ccccttcagt tgcacccgtt ttcccaggag aacggctgct attctttaga
6361 tcataccttc ctctcaaagg tggttatggc aacccagcca ttgactgtct gctgccacag
6421 gagtggatac aacacttcta tcaagaagct gccccctcaa tgagtgaggt ggcccttgtt
6481 aggtacatca acccagacac tggtcgggcg ctgtttgagg ccaagctcca tagagctggc
6541 ttcatgacag tctcgagtaa caccagtgct ccagtagtcg tgcctgccaa cgggtacttc
6601 agatttgact cctgggtaaa tcaattttac tctctcgccc ccatgggaac tggcaatggg
6661 cgcagaagga tccaataatg gctggtgcct tcatagctgg tcttgcaggg gacgtgctca
6721 gcaatgggct cggctcacta atcaatgcag gtgctaatgc aataaatcag agagcagagt
6781 ttgattttaa tcagaaatta cagcaaaatt cttttaatca tgataaggag atgttgcagg
6841 ctcagattca agcaaccaag cagctgcagg cagacatgat ggctataaag cagggggtgt
6901 tgaccgctgg cggcttctct cctgctgatg cagccagagg cgctgtaaac gcgcccatga
6961 cacaagcgct ggattggaat ggtacaaggt attgggcacc aggctccatg aggacaactt
7021 cttactccgg aaggtttaca tcagccgctc caacaaggca ggctgacttt caacacactc
7081 agggccgacc ttcgagtggt tcttccgttt cctcctactc cacacaatcc tcaagaccaa
7141 ccttaaccac aactacaggg tcctcacata gcacaacatc atccaatttg acccgcagca
7201 caaatcttcc ctcgactact tctagagcaa cctctaggac tagtgaatgg gttagagaac
7261 aaaatagaaa tttggaaccc tacatgcatg gtgccttaca aacagccttt gtcacaccac
7321 catctagcag ggcatccgac gggacggtct caaccgttcc caagggtgtt ttggactcct
7381 ggacacctgc gtttaacacc cgcaggcagc cgctttttgc acacctccgt aagagggggg
7441 agtcacaagt ttagtgaaaa ggtaaaattt taaaataatc ttattctgcc tttt
//