Typing tool
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Typing tool
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Complete norovirus genomes
| MW305582 | GII.17 | |
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| GII.P13 |
ORF1: 1..5040
ORF2: 5021..6634
ORF3: 6634..7404
LOCUS MW305582 7446 bp RNA linear VRL 18-JUL-2024
DEFINITION Norovirus GII isolate T055 nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MW305582
VERSION MW305582.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7446)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A.U.A., Ford-Siltz,L.A., Green,K.Y.,
Galeano,M.E., Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N.,
Ushijima,H. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses provide insights on
evolutionary dynamics and evidence of coexisting viral populations
evolving under recombination constraints
JOURNAL PLoS Pathog 17 (7), e1009744 (2021)
PUBMED 34255807
REFERENCE 2 (bases 1 to 7446)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7446
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="T055"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Tunisia"
/collection_date="15-Jul-1977"
/note="genotype: GII.17[GII.P13]"
gene <1..5040
/gene="ORF1"
CDS <1..5040
/gene="ORF1"
/codon_start=1
/product="nonstructural polyprotein"
/protein_id="QPJ59082.1"
/translation="KSSSDGLFANMTVTFKKALGARPKQPPPGETKQISKPPRPPTPE
LVKRIPPPPPNGEDEPKVVYRVGEGVSGLPDLTTVTQPDAQNTAYSVPPLSQREVGDA
KEPLPGSILEMWDGEIYHYGLYVERGHILGVHKPPAAISLAKIELTPLSLYWRVVYTP
QYLIAPDTLKNLSGESFPYTAFDNNCYAFCCWVLDLNDSWLSRRMIQRTTGFFRPYQD
WNRKPLPTMDEPKIKKVANAVLCALSSLFTRPIKDIIGKLKPMNILNILATCDWTFAG
IVESLILLAELFGVFWTPPDVSAMIAPLLGDYEMQGPEDLAVELVPVVMGGIGLVLGF
TKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKEEANELAIVRAIEDAVL
DLEAIENNHLTTLLKDKDSLATYMRTLDLEEEKARKLSTKSASPDIVGTINSLLARIA
AARSLVHKAKEELSSRQRPVVVMMSGRPGIGKTHLAREIAKKVASTLAGDQRIGLVPR
NGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTCPLTLNCDRIENKGKVFDSD
VIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPDIEKAKRDFPGQPDMWKDHYRPD
FSHIKLQLAPQGGFDKNGNTPHGKGVMKSLTVGSLIARASGLLHERMDEFELQGPNLP
TFNFDRNKVTAFRQLAAENKYGMMDTLRVGNQLKSVKTMDELKQAIRNITIKKCQIVY
NGCTYTMESDGRGKVSVDKVQNATVQTNNELVGALHHLRSARIRYYVKCFQEAIYSLL
QIAGAAFVTSRIVRRMNISSLWSKPPVEDNESEDKEGCPKPRDEDEFTVDSKDIKVEG
KKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERHGKYSIEEYLQDRDRYYEELAI
AKATEEDFCEEEEAKIRQRIFRPTRKQRKEERATLGLVTGSEIRKRNPDDFKPKGKLW
ADDNRSVDYNERIDFEAPPSIWSRIVNFGSGWGFWVSPSLFITSTHVIPKGITEAFGV
PISQIQIHKSGEFCRLRFPKPIRTDVSGMILEEGAPEGTVATILVKRPTGELMPLAAR
MGTHAAMKIQGRMVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGNDFVVIGVHT
AAARGGNTVICATQGSEGEATLEGGDNRGTYCGAPILGPGNAPKLSTKTKFWRSSNAP
LPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPRGKPPNPSVLESAKKTIINV
LEQTIDPPQKWTYAQACASLDKTTSSGHPHHVRKNDYWSGESFIGKLADQASKANLMY
EEGKHMTPVYTAALKDELVKTDKIYGKIKKRLLWGSDLSTMIRCARAFGGLMDELKAH
CITLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQQRAVLAAALEIMVRFSA
EPQLAQIVAEDLLSPSVVDVGDFKITINEGLPSGVPCTSQWNSISHWLLTLCALSEVT
GLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTTKLKEYGLKPTRPDKTEGPLVISE
DLNGLTFLRRTVTRDPAGWFGKLDQSSILRQLYWTRGPNHEDPSETMIPHAQRPVQLM
ALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQESMFRWMRFSDLSTWEGDRNL
APSFVNEDGVE"
mat_peptide <1..933
/gene="ORF1"
/product="p48"
mat_peptide 934..2031
/gene="ORF1"
/product="NTPase"
mat_peptide 2032..2565
/gene="ORF1"
/product="p22"
mat_peptide 2566..2964
/gene="ORF1"
/product="VPg"
mat_peptide 2965..3507
/gene="ORF1"
/product="Pro"
mat_peptide 3508..5037
/gene="ORF1"
/product="RdRp"
gene 5021..6634
/gene="ORF2"
CDS 5021..6634
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ59083.1"
/translation="MKMASSDAAPSNDGATGLVPEINHETLPLEPVAGAAIAAPVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHLIVDVRTLEPIMIPLPD
VRNTFFHYNNQPAQRMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTISELTNSRFPAPIDSLFTAQNNALNVQCQNGRCTLDGELQGTT
QLLPSGICAFRGRLTADVNQQHDDRWHMQLTNLNGTPFDPTEDVPAPLGTPDFTGLLY
GVASQRNSDNTTRAHEVVISTTSSQFVPKLGSINFGSTSTDFQLQQPTRFTPVGIKIE
DGHEFNQWTLPRYSGHLTLNMNLAPPIAPNFPGEQLLFFRSNVPCAGGINAGIIDCLL
PQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRSGYITVAHSGDYPLVVPS
NGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6634..7404
/gene="ORF3"
CDS 6634..7404
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ59084.1"
/translation="MAGAFIAGLAGDMLTNAVGSLANAGANAITQKIDFENNKQLQSA
SFQHDKDMLQAQVAATKQLQADMIAIKQGILTAGGFSPTDAARGAVGAPMTKVLDWSG
TRYWAPNSTKTTSYSGQFTSTPVHMPVKQPTPVRKTQPPSSSSGSVYSLSTQSTTLSV
PSSSSSAPSASTQLTKLSSASSMDRTANWVNQQRSLSPYMSGALNISHVTPPSSRASS
SGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 aagtcttcaa gtgacggctt gtttgctaac atgactgtca cttttaagaa ggccctcggg
61 gcgcggccta aacagccgcc cccgggagaa acaaaacaaa tatctaaacc accaagacca
121 ccgacaccgg aattggtgaa gagaataccc ccacccccac ccaatggtga agatgagcca
181 aaggtggtgt acagggtggg agaaggtgta tctgggctgc ctgacttaac aaccgtcacg
241 cagcctgacg cacaaaacac agcctatagt gttcccccac tcagtcaaag agaggtgggt
301 gacgcgaagg aaccactacc tgggtccatc ttggaaatgt gggacggcga gatctaccac
361 tatgggctgt acgtggagcg tggtcatata ctcggggtac acaaaccacc cgctgcaata
421 agcctcgcta aaattgagtt aacaccattg tctctctact ggagggtggt ttacaccccc
481 cagtatttga tagctccaga cactttgaag aacttgagtg gagagtcatt tccctacacg
541 gcttttgata acaactgtta tgctttttgc tgctgggtcc tggatctcaa cgattcttgg
601 cttagtagaa ggatgatcca aagaacgacc ggtttcttta gaccatatca ggattggaac
661 agaaagcccc tgccaaccat ggatgaacct aaaatcaaga aggtcgcgaa tgccgtccta
721 tgtgccctct cttcactctt cactaggcct attaaggaca ttattggaaa gctcaaacca
781 atgaacatcc tcaatatact ggctacttgt gactggactt ttgcaggcat agtggaatcc
841 cttattcttc ttgccgaact ctttggggtg ttctggacac ccccagatgt gtctgcgatg
901 attgctccct tgctcggcga ctacgagatg caaggtcccg aagacctggc cgtggaactc
961 gtgcccgtag taatgggagg gataggtctg gtgctgggat tcaccaagga aaagatcggc
1021 aagatgctct catcggctgc atccacactc agagcctgca aagacctagg ggcttacgga
1081 ttggaaatac tcaaattagt tatgaaatgg ttcttcccta agaaagagga ggctaatgag
1141 ttagctatag tgagagccat tgaagatgct gtcttagacc tggaggcaat agaaaacaac
1201 cacttgacca ctctcctcaa ggataaggac agcctggcca catacatgag gactcttgac
1261 ttagaggaag agaaagcaag aaagctctcc accaaatctg catcaccaga cattgtaggc
1321 acaataaact cattgttggc aagaattgca gctgctaggt cactagtcca caaggcaaag
1381 gaggaattgt caagcagaca gaggcctgtc gtcgtaatga tgtctggcag accaggcata
1441 gggaaaaccc acctcgccag agagatagct aagaaggttg catcaacgtt ggcgggtgat
1501 caaagaattg ggttggtgcc caggaacggt gtggaccact gggacgccta caaaggagaa
1561 agggtggtgc tatgggatga ctatggcatg agcaacccta tacaggatgc tctaagactc
1621 caagagttgg ccgacacctg ccctctaaca ctaaattgtg acagaattga aaacaaggga
1681 aaagtgtttg acagcgatgt cataatcata acaaccaacc ttgcaaaccc agcaccactg
1741 gattatgtca actttgaggc ctgctccaga cgcatagact tcttagtgta tgcagatgca
1801 ccagacattg aaaaggccaa gcgtgacttc cctggccaac cagacatgtg gaaagatcat
1861 tacagaccag acttctcaca catcaagctc cagctagcac cgcagggtgg ttttgacaag
1921 aatggtaaca ccccacatgg caaaggtgtg atgaaatccc tgacggtcgg atcattgatc
1981 gccagggctt ctggattact ccatgagaga atggatgaat ttgaactcca aggccctaac
2041 ctaccaactt tcaactttga ccgcaacaaa gtcaccgcct ttaggcaatt ggcagctgaa
2101 aacaaatatg gtatgatgga cacactgagg gttggcaacc aactgaaaag tgttaaaacc
2161 atggatgaac ttaaacaagc catcagaaac atcaccatca aaaagtgcca gatagtgtac
2221 aatggatgca cctacaccat ggagtctgac gggcgtggca aagtgtcagt tgacaaagtg
2281 caaaatgcaa cagttcaaac caacaacgaa cttgtgggag cgctacacca cctaaggtct
2341 gcaagaataa gatactatgt caagtgcttc caggaggcaa tctactcctt gttgcaaatt
2401 gctggtgcag cctttgtcac ctcacgcatc gtgaggcgca tgaacatatc aagtctctgg
2461 tcaaagccac ccgttgaaga caatgagtca gaagacaaag aggggtgccc caagcccaga
2521 gatgaggatg agttcactgt tgactccaag gacatcaagg tggaaggaaa gaaaggcaag
2581 aacaagtctg gcagaggaaa gaaacacacg gctttctcca gtaagggcct cagtgatgaa
2641 gagtacgatg agtataaaag aatcagagaa gaaaggcatg gcaaatactc aatagaggaa
2701 tacctccaag atagggacag gtactatgaa gaactcgcca tcgctaaggc cactgaggag
2761 gacttctgtg aagaggagga agctaaaatc cgccagagaa tcttccgccc caccaggaaa
2821 cagcggaagg aggaaagggc cacactcgga ctcgtcacgg ggtcagaaat cagaaagagg
2881 aacccagatg acttcaaacc aaaggggaaa ctgtgggctg acgacaacag gagtgtggat
2941 tacaatgaga gaatagattt tgaggcacct ccaagcattt ggtcaagaat agtcaacttt
3001 ggttcaggtt gggggttttg ggtctcccca agtctcttca taacttcaac ccacgtgata
3061 ccgaaaggaa tcacggaggc ttttggtgta cccatcagtc aaatacaaat ccacaagtca
3121 ggggaattct gccgcttgcg gtttccaaaa ccaatcagga cagatgtgag tgggatgatt
3181 ttagaagagg gtgcccctga gggaaccgtt gcaaccattc ttgtcaagcg accaacaggg
3241 gaactaatgc ccctagcggc cagaatgggg acccatgccg caatgaagat ccaagggaga
3301 atggtgggtg gtcagatggg tatgttgctt accggttcaa acgccaaaag catggacctt
3361 ggcacaacac caggtgattg tggatgccct tacatataca aaagaggcaa tgacttcgta
3421 gtcatcggcg tgcacaccgc agcagcacgt ggaggcaaca cagtcatatg tgccacacag
3481 gggagcgaag gtgaggccac tcttgaaggt ggtgacaaca ggggcaccta ctgcggagct
3541 cccatcctgg ggcctggtaa cgcaccaaaa ctgagcacca aaacaaaatt ttggaggtct
3601 tccaacgcac cactcccacc aggcacctat gaaccagcat acctaggtgg gagagaccca
3661 cgtgtgaagg gaggtccgtc cttgcaacag gtcatgagag accagctcaa gccttttact
3721 gaacccagag gaaaaccacc aaacccaagt gttttagaat cagcaaagaa aaccatcatt
3781 aatgtcttgg aacaaaccat tgatcccccc cagaaatgga cctacgccca agcatgtgca
3841 tctcttgaca aaacaacctc cagcggtcat ccacatcacg tccgtaagaa tgactactgg
3901 agtggtgagt ccttcatagg caagctagca gaccaggcat caaaggcaaa tctcatgtac
3961 gaggagggta aacacatgac accagtgtac accgcagctc tcaaggatga gctggtgaaa
4021 actgacaaaa tttatggtaa gatcaagaaa agactcttat ggggttccga cctctccacc
4081 atgattcggt gtgccagggc attcggcggt ctcatggatg agctcaaagc acattgcatc
4141 actctccctg tcagagttgg catgaatatg aatgaagatg gacccataat atttgagaaa
4201 cattccagat acagatacca ctatgatgca gactattccc gttgggattc cacacagcaa
4261 cgggcagtgc tagcagcagc acttgaaatc atggtgagat tttctgcaga accacaattg
4321 gcacagatag tggctgagga cctgctgtcg ccgagcgtgg ttgacgtggg cgattttaag
4381 attacaatca atgagggtct gccatctggc gtgccttgca cgtctcaatg gaattccatc
4441 tcccactggt tgctcacctt atgtgccctg tctgaagtga caggactggg ccctgacatc
4501 atacaagcta actccatgta ttctttctat ggtgatgatg aaattgtaag cactgacata
4561 aaattggacc cagaaaagct aactacaaaa cttaaggaat atggcctcaa acccactcgc
4621 cctgacaaaa ctgaggggcc actggtgatc agtgaagact tgaacgggtt aacgttcctc
4681 cgtcggacag tgacccgtga tccagcaggt tggttcggaa agttggacca aagttccatc
4741 ctcaggcagt tatattggac aagaggaccc aaccatgaag atcctagtga aaccatgata
4801 ccacacgcac aaagacccgt gcagctcatg gcattgttag gagaatcctc cctacatgga
4861 ccctcatttt acagcaaagt tagcaaattg gttatatctg aacttaagga gggaggaatg
4921 gatttttatg tgcccagaca agagtcaatg ttcagatgga tgaggttctc agatctaagc
4981 acatgggagg gcgatcgcaa tctggctccc agttttgtga atgaagatgg cgtcgagtga
5041 cgccgctcca tctaatgatg gtgctacggg cctcgtccca gagatcaacc acgagaccct
5101 tcctctagaa ccagtggcag gcgcagctat tgccgcaccc gtcactggtc aaaataacat
5161 aattgatccc tggataagaa caaattttgt acaagcaccc aatggggagt ttacggtttc
5221 acctaggaac tctcctggag aaatcctcct aaatttggaa ttaggccctg atttgaatcc
5281 ttatttggca catctgtcta gaatgtacaa tgggtatgct ggtggtgtgg aagtccaagt
5341 cctcctagcg gggaacgcgt tcactgcagg aaagattctt ttcgctgccg tgccaccaaa
5401 tttcccagtt gaattcttga gtcctgccca aatcactatg ctaccacatt tgattgttga
5461 tgtcagaacc cttgagccca ttatgatacc actccctgat gttagaaaca ccttcttcca
5521 ttataataat cagcctgccc aacgcatgcg cctagtggcc atgttataca cccctctgag
5581 gtccaatggt tctggtgatg atgttttcac tgtttcttgc agagttttga ctagacccac
5641 cccagatttt gagtttacat atttggtccc cccttcggtg gagtctaaaa ctaaaccctt
5701 ttccctgccc attttaacta tctctgagct gactaattca agatttcctg cacctataga
5761 ttcactgttc acggcccaaa acaatgccct caatgtccaa tgccagaatg gccggtgcac
5821 actggatggt gagctacagg gaaccactca actgttgcca tcaggtatat gtgccttcag
5881 aggcaggttg acagcagatg taaatcagca acacgatgac agatggcaca tgcaactgac
5941 aaaccttaat ggaactccct ttgatccaac agaggatgtg ccagcccctc taggtacccc
6001 agactttaca ggtctcctct acggtgtggc cagccagaga aacagtgaca acaccaccag
6061 agcacacgag gtcgtgattt ccacaactag ctcacaattc gtgcctaaat tggggtcaat
6121 caactttggg agtacaagta ctgattttca gttgcagcaa cccaccagat ttacaccggt
6181 tggaatcaaa attgaagacg gacatgaatt taatcaatgg accctaccca ggtattcagg
6241 ccatttgacc cttaacatga accttgcccc acctattgct ccaaatttcc ctggtgaaca
6301 gttgctattc tttagatcaa atgtcccttg tgccggtggc atcaatgctg gcatcattga
6361 ctgcctgttg cctcaagagt ggatacagca tttctatcag gaatctgccc cctctcaatc
6421 agacgtggcc ctaatcaggt atgtcaaccc tgacacaggg cgcacgctct ttgaggcaaa
6481 gctccacaga tcaggttaca tcactgttgc ccactcaggt gactatccac ttgttgtccc
6541 ctctaatgga tactttagat ttgattcttg ggtgaaccag ttttactcac ttgcccccat
6601 gggaacaggg aatgggcgca gacgggtgca gtaatggcag gagcttttat agcaggtctt
6661 gcaggtgaca tgctcaccaa cgcagtcggc tcactggcaa acgctggggc caatgccata
6721 acccaaaaga tagattttga gaacaacaag cagctccaat ctgcctcttt ccagcatgac
6781 aaagacatgc tccaagcaca ggtagctgcc accaaacaat tgcaggctga catgatcgcc
6841 atcaaacagg ggatactgac cgctggcggc ttctccccta ctgatgcggc gagaggagca
6901 gtgggtgcac ccatgaccaa ggtccttgat tggtccggca ctcgctattg ggcaccaaat
6961 tccacaaaaa caaccagcta ttcgggacag ttcacatcaa cgcccgtaca catgcctgtt
7021 aaacagccca cccctgttag aaagacccag cccccttcct cttcttctgg tagtgtctat
7081 agtctttcaa cacagagtac cactttgtct gtaccttctt ccagttcttc tgctccttct
7141 gcttcaacgc aattaacaaa attgagttca gcttcctcta tggataggac agcaaattgg
7201 gttaatcaac agagaagcct tagcccctac atgagcggtg ctctcaacat ctctcacgtg
7261 acacctccgt cgagcagggc ttcaagttcg gggacagtct caactgtgcc caaagaagtt
7321 ttggactcct ggacatctgc attcaacaca cgcagacagc cgctcttcgc acacctcaga
7381 gtgagggggg agtcacgagt ttagtgaaaa gaatcaattg attttaaatt agatttaaat
7441 tggatt
//