Typing tool
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Typing tool
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Complete norovirus genomes
| MW305564 | GII.6 | |
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| GII.P7 |
ORF1: 1..5063
ORF2: 5044..6687
ORF3: 6687..7466
LOCUS MW305564 7491 bp RNA linear VRL 06-JUL-2021
DEFINITION Norovirus GII isolate 522SR nonstructural polyprotein (ORF1) gene,
partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete cds.
ACCESSION MW305564
VERSION MW305564.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7491)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses reveal coexistence of
viral populations evolving under recombination constraints
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7491)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7491
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="522SR"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Paraguay"
/collection_date="2004"
/note="genotype: GII.6[GII.P7]"
gene <1..5063
/gene="ORF1"
CDS <1..5063
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QPJ59028.1"
/translation="FGSQNSVNDSINTAPSNKEEVGAFSNIKVGFKKMLGAVPKGTKA
PSSDQHCPTVKIGTKTLTVPPEPPNGEGTVQFDAKSETVRGLPDLTTVQNEHENTPYT
VPPLSEREHRPATEPLPGTILEMWDGEFYHYSVYVSGGKALGVHKPPAAISLATIELT
PISLYWRPVYTPNYLVCPDTLKGLAGEKFPYTAFSNNCYNFCCWVLELNDTWLSRRSI
SRTTGFFKPYQSWNRKPLPTVDDGKIKKVANAILCALGSLFSKPIKDLLGKLKPLNLL
HLLASCDWTFAGIVETVILMAELFNIFWTPPDVSNFIASLIGDFELQGPEDLAVELVP
VVMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMKWFFPKKEEKAE
METLRAIEDAVLDMEAIGNNHLTTLLKDKDSLTAFMKTLDLEEEKARKLSTKSSSPDI
VGTINAILARIAAARSLLHKAKEEMFSRIRPVVVMISGRPGIGKTHMARHLAKSIANT
MSGDQRVGLVPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALTLQELADTCPVTLNCD
RIENKGKMFDSDVIIITTNLVNPAPLDYVNFEACSRRVDFLVYAESPEIEKVKRDFPG
QPDMWKDHFKPDFSHIKLTLAPQGGFDKNGNTPHGKGTMRSLTQGSLTARVAGLVHER
RDEFQLQGNDFQTYNFDTNRVSAFRRLAADNKYGIMETMRVGAALKNVKTLEDLKIAL
RDVKFNECEIIYRNSKYRVSSNGKGSVSVDKVEDQTSQTANEVGSALLRLRQARARYY
VSCFQDLVYTLIQVAGASFVVNRISKRFCWERWVKPTEAQETSESEKEVAQGRWEIEP
KDTEPEGKKGKNKKGRGKKHTAFSSKGLSDEEYDEFKRIREERNGKYSIEEYLQDRDR
YYEEVAVARATEEDFCEEEEAKIRQRIFRPTKKQRKEERGVLGLVTGSDIRKRRPDDF
QPKGNLWADDTRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSNLLITTTHVLPKG
IKELFGVEIKQIQIHKSGEFCRFRFPRPIRPDVTGLVLEEGAPEGTVCSILVKRPTGE
MIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDCGCPYIYKRGNDI
VVAGVHTAAARGGNTVICATQGQDGEAVLEGNENLGTYCGAPILGPGKAPKLSTKTKF
WRSSPDALPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEPRGKPPRPAVLEEA
KKTVMNVLEQTIDPAKPWTYSQACASLDKTTSSGSPHHVKKDDHWNGESFTGPLADQA
SKANLMYEQAKHVQPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGTMIRCARAFGGL
MDSMKASCIALPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDSTQQRSILSAAME
VMVRFSAEPELAQVVAEDLLAPSQLDVGDFVISVQEGLPSGVPCTSQWNSIAHWILTL
SAMAEVSGLSPDVVQAHSCFSFYGDDEIVSTDINLDPMKLTQKLREYGLVPTRPDKTE
GPLVITEDLTGLTFLRRSIARDPAGWFGKLDQDSILRQLYWTRGPNHENPYESMVPHS
QRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEAMFRWMRFSDLST
WEGDRNLAPEGVNEDGVE"
mat_peptide <1..971
/gene="ORF1"
/product="p48"
mat_peptide 972..2069
/gene="ORF1"
/product="NTPase"
mat_peptide 2070..2588
/gene="ORF1"
/product="p22"
mat_peptide 2589..2987
/gene="ORF1"
/product="VPg"
mat_peptide 2988..3530
/gene="ORF1"
/product="Pro"
mat_peptide 3531..5060
/gene="ORF1"
/product="RdRp"
gene 5044..6687
/gene="ORF2"
CDS 5044..6687
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ59029.1"
/translation="MKMASNDAAPSNDGAANLVPEANNEVMALEPVVGASIAAPVVGQ
QNIIDPWIRENFVQAPQGEFTVSPRNSPGEMLLNLELGPELNPYLSHLSRMYNGYAGG
MQVQVVLAGNAFTAGKIIFAAVPPHFPVENISAAQITMCPHVIVDVRQLEPVLLPLPD
IRNRFFHYNQENTPRMRLVAMLYTPLRANSGEDVFTVSCRVLTRPAPDFEFTFLVPPT
VESKTKPFTLPILTLGELSNSRFPAPIDMLYTDPNEGIVVQPQNGRCTLDGTLQGTTQ
LVPTQICAFRGTLIGQTSRSSDSTDSVPRRRDHPLHVQLKNLDGTQYDPTDEVPAVLG
AIDFKGTVFGVASQRDVSGSQVGATRAHEVHINTTDPRYTPKLGSILMHSESDDFVTG
QPVRFTPIGMGDNDWHQWELPDYSGHLTLNMNLAPAVAPAFPGERILFFRSIVPSAGG
YGSGQIDCLIPQEWVQHFYQEAAPSQSAVALIRYVNPDTGRNIFEAKLHREGFITVAN
SGNNPIVVPPNGYFRFEAWVNQFYTLTPMGTGQGRRRNQ"
gene 6687..7466
/gene="ORF3"
CDS 6687..7466
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ59030.1"
/translation="MASAFLAGLAGDVITNGVGSLINAGANAINQKVEYDFNKQLQMA
SFKHDKEMLQSQVLATKQLQQEMMNIRQGVLTAGGFSPADAARGAVNAPMTKILDWNG
TRYWAPNSMKTTSYSGQFSSSPVHKSPASSQHVAPSKGRLQNDSASVYSFPSSVSSQS
THSTVLSAGTGSSRSITTSTTTPTLSRTSDWVRGQNERLSPFMDGALQTAFVTPPSSK
ASSNGTVSTVPKAVLDSWTPMFNTHRQPLFAHLRRRGESQV"
ORIGIN
1 cctttggcag ccaaaactct gtcaatgaca gtatcaacac cgccccttct aataaagaag
61 aggttggtgc attttccaac atcaaagttg gttttaagaa aatgctgggt gccgttccca
121 aggggaccaa agcacccagt agtgatcagc actgccccac agttaagatc gggaccaaaa
181 cattaacagt tccccctgag cccccaaatg gtgaaggcac cgtgcagttt gatgcgaagt
241 cagaaactgt gcgtgggcta ccagacttaa caacggtgca aaatgaacac gaaaacacac
301 catacactgt ccccccattg agtgaaaggg aacacagacc agccactgag ccgcttcctg
361 gcacaatact ggagatgtgg gatggtgaat tctaccatta ctccgtgtac gtcagcggcg
421 gcaaagccct aggggttcac aagccccctg cagcaataag cctcgcgacg atagagctca
481 cacccatatc tctttactgg aggcccgttt acacccccaa ctacctggtc tgtccagaca
541 cgttgaaagg cctcgctggt gagaagtttc cctacacggc cttcagcaac aattgttaca
601 acttctgttg ctgggtgctt gagctcaatg acacgtggct tagcaggagg agcatctcca
661 ggactaccgg cttcttcaaa ccatatcaat cttggaacag gaaacccctt ccaaccgttg
721 atgatggaaa gatcaaaaag gtggccaacg caatcctctg tgcacttgga tcactgttct
781 caaaaccaat caaagacctg ttgggcaaac ttaaaccatt aaacttgctg cacttgctcg
841 catcatgtga ttggacgttt gcgggtatag tggagacagt tatcctaatg gcggaacttt
901 tcaacatctt ttggacaccg ccagatgttt ccaacttcat agcctccctg ataggtgatt
961 ttgaattgca agggcctgag gacctggctg tggagcttgt ccccgtggtc atgggtggca
1021 taggaatggt tctcggcttt actgctgaga agataggacg catgctgtcg tccgctgcat
1081 caacactgcg ggcatgcaaa gacctgggga attatgccct tgacatatta aaactggtta
1141 tgaagtggtt cttcccaaag aaagaagaga aagccgagat ggaaacctta agggcgattg
1201 aggatgccgt cctggacatg gaagctatag gaaacaatca tctcacaacc ctcctcaagg
1261 ataaggacag cctcacggct ttcatgaaaa ctctggacct agaagaggag aaggcaagga
1321 aactgtctac caaatcatcc tcgccagaca tcgtcggcac tatcaatgcc atattggcca
1381 gaatagctgc tgccaggtcc ctcctacaca aggctaaaga agaaatgttt agcaggatca
1441 gacccgtggt tgttatgatc tcgggtagac ctggcattgg caaaacccac atggcaagac
1501 acctggctaa gagcatcgcc aacaccatga gtggcgacca gagagtcggg ctcgttccac
1561 gcaacggggt cgatcactgg gacgcctaca ggggagagag ggtggtctta tgggatgatt
1621 atggcatggg aaaccctgtc aaagatgccc taacactgca agagttggct gacacctgcc
1681 cagtaactct aaactgtgac aggattgaga acaaggggaa gatgttcgac agtgatgtca
1741 tcataatcac gaccaattta gtcaacccag cgcccctcga ttatgtaaac ttcgaggcgt
1801 gctccagaag ggttgacttt ctggtctatg cggagtcacc agagattgag aaggttaaga
1861 gagatttccc cggccaacct gacatgtgga aggaccattt taagccggac ttctcccaca
1921 taaagctgac tctagcccct cagggcggat tcgacaagaa tggcaacacc ccgcatggta
1981 agggcaccat gcgatcccta acccaggggt ccctgactgc aagggttgca ggccttgttc
2041 atgagagaag agatgagttt cagctccagg ggaacgactt tcaaacatac aactttgaca
2101 ccaacagggt ctccgcattt aggaggctgg ccgcagacaa caagtatgga atcatggaaa
2161 caatgagagt gggtgcggcg cttaagaatg tcaagacctt ggaagatctg aaaattgccc
2221 tgagggatgt gaagttcaat gagtgtgaga taatttacag gaactccaaa taccgagtct
2281 cttccaacgg taaaggttct gtctctgttg acaaagttga ggaccaaaca tcccagactg
2341 caaacgaagt gggctcagca ctccttagac tcaggcaggc aagggccaga tactatgtca
2401 gctgcttcca agatctcgtc tacactctaa tacaggttgc cggagcatca ttcgttgtca
2461 acagaatctc caagaggttc tgttgggaga gatgggtcaa accaaccgaa gcccaggaaa
2521 cgagtgaatc cgaaaaggaa gtagcccaag gtagatggga gattgaaccc aaggacacag
2581 aaccagaagg taagaagggc aagaacaaga aaggaagagg caagaaacac acagctttct
2641 ccagcaaagg cctgagtgat gaggagtatg acgagttcaa gagaatcagg gaagaaagga
2701 acgggaaata ctccattgag gaatacctgc aagaccggga tcgctactat gaggaagtgg
2761 cagttgcccg ggcaacagag gaggacttct gtgaagagga ggaggccaag ataagacaaa
2821 gaatcttccg tcctacaaag aaacaaagga aggaagaaag gggggtgctt ggtttggtta
2881 ctggttcaga catcaggaag aggagaccag acgattttca accaaagggc aatctgtggg
2941 cagacgacac cagaagtgtg gactacaacg agaggcttga tttcgaggct cccccgagtg
3001 tctggtcgag aatagtccca ttgggcactg gctggggctt ctgggtctca tccaacctcc
3061 tgatcacgac aacacacgtc ctgcctaagg ggattaagga actttttgga gttgaaatca
3121 aacagatcca aattcataag tctggagagt tttgcaggtt cagattccca aggccaatca
3181 ggccagatgt cacagggctc gtgttggagg aaggtgctcc agaaggcact gtctgctcca
3241 tactcgtaaa gagacctaca ggtgagatga tccccctggc agtgaggatg ggcacgcatg
3301 catccatgaa aatacagggt aggaccgtcg gtggccagat gggaatgctc ctcacagggg
3361 caaacgcgaa aaacatggat cttggcaccg gtcctggtga ctgcggttgt ccttacatct
3421 acaaacgtgg caatgacata gttgtcgcgg gtgtccacac cgcagcagcc cggggaggca
3481 acactgtcat atgtgccacc caaggacaag atggggaggc agtccttgag ggaaatgaga
3541 accttggcac ttactgcggt gccccaatct tgggtccagg caaggcgccc aaacttagta
3601 cgaagaccaa attctggcgt tcatcaccag acgctttgcc gccaggcact tatgagcctg
3661 cctacctggg aggcaaggat cccagagtgg aaaaaggacc gtccctgcag caagtcatga
3721 gggaccaact aaaacctttc acagaaccca ggggcaaacc acctagacct gcggtcttag
3781 aagaagccaa aaagacagtg atgaatgttc tagaacaaac catcgaccct gctaagccat
3841 ggacctattc ccaagcatgt gcctcactgg acaagaccac ttccagtggt agcccccatc
3901 atgtcaagaa agatgaccat tggaatggag aatccttcac cggccccctt gcagaccaag
3961 catccaaagc caacctcatg tatgagcagg ccaaacatgt gcagcccgtg tacacggccg
4021 cactcaaaga tgagcttgtc aagactgaca agatctacaa aaagataaag aagaggctct
4081 tatgggggtc ggatcttggc acaatgatca ggtgcgccag ggcctttggt ggtcttatgg
4141 atagcatgaa ggcaagttgt atagccctcc cgtgcagggt agggatgaac atgaatgaag
4201 atggtcccat catatttgac aaacactcta agtacaggta ccactatgat gctgactatt
4261 ccaggtggga ttcaacccag caaaggagca ttctctcggc cgctatggaa gtgatggtgc
4321 ggttttctgc cgaaccagag ctggcacaag tggttgcaga ggacctcctg gcacccagcc
4381 aactagatgt tggcgatttc gtcatctcag tccaggaggg tctgccatca ggggtcccat
4441 gcacatcaca gtggaattca atagcacatt ggatcctaac cttgagtgca atggcagaag
4501 tgtcaggtct ctcgccagat gttgttcaag cccactcctg tttctcattt tacggcgatg
4561 atgagatcgt cagcactgat atcaaccttg atcccatgaa gttgacacag aagctcagag
4621 agtatggtct ggtccccacc cgacctgaca aaactgaagg ccccctcgta ataactgaag
4681 acctcaccgg cctaacgttc ctgcgtaggt caattgcacg agacccagct gggtggtttg
4741 gaaaactgga ccaagactca atcctcagac agttatactg gacaaggggc cccaatcatg
4801 agaatccata tgagagcatg gtccctcatt cccagcgggc cacacagctc atggcccttc
4861 tcggcgaggc ttcactgcat ggcccccagt tttacaagaa agttagcaag atggtcatca
4921 atgaaatcaa aagtggtggt ctggaatttt atgtgcccag acaagaggcc atgtttagat
4981 ggatgagatt ctctgacctc agcacatggg agggcgatcg caatcttgct cccgagggtg
5041 tgaatgaaga tggcgtcgaa tgacgctgct ccatcgaatg atggtgctgc caacctcgta
5101 ccagaggcca acaatgaggt tatggcactt gaaccggtgg tgggagcctc aatcgcggct
5161 cctgtcgtcg gccaacaaaa cataattgac ccctggatta gagaaaattt tgtccaagca
5221 ccacagggcg agtttaccgt ctcaccgagg aactcgcctg gtgagatgct attaaatctt
5281 gaattgggcc cagaacttaa cccctatcta agccatttgt cccgtatgta caacgggtat
5341 gctggtggta tgcaggttca ggtggtcctg gctgggaatg cgttcacagc tgggaaaatc
5401 atctttgccg ccgtaccacc acattttccc gtagaaaaca tcagtgcagc ccaaataact
5461 atgtgccccc atgtaatcgt tgatgtgaga caacttgaac cagtacttct gcccctccct
5521 gacataagaa acaggttctt tcattacaat caggagaaca ccccccggat gagacttgtg
5581 gctatgcttt atacccccct gagggctaac tctggtgagg atgtgtttac tgtctcttgt
5641 agggtcttga cccgccctgc ccctgatttt gaatttactt tcttggtgcc accaactgtt
5701 gaatcaaaga ccaaaccttt tacactgccc atattaactc ttggtgagct atctaactct
5761 agattcccag ccccgataga catgttgtac actgacccaa atgaggggat tgtggtccaa
5821 ccacaaaatg gtaggtgcac tcttgatggc acgctgcaag gcaccacaca actggtcccc
5881 acccaaattt gtgccttcag gggcacacta attggccaaa catcaagatc ttcagactcg
5941 accgactcag tccctcggag aagggatcac ccactccatg tgcaattaaa gaatcttgat
6001 ggcacgcagt acgacccaac tgatgaagtg ccagcagtcc ttggtgccat tgacttcaag
6061 gggaccgtct ttggggtggc cagtcagaga gacgtgtcag ggagtcaagt gggggcaact
6121 cgagctcatg aagtgcacat caacacaacc gatcctaggt acacaccaaa actgggatcc
6181 atcctcatgc actcagagtc ggacgacttt gtgactggac agccggtgcg cttcacaccc
6241 ataggaatgg gtgacaacga ctggcaccag tgggagctgc ctgactactc tggacaccta
6301 accctgaaca tgaaccttgc cccagcggtt gctcctgctt ttccgggcga gaggattctt
6361 ttcttcaggt caatagtccc ttctgctggt ggctatgggt ctggacaaat agattgcctc
6421 ataccacagg agtgggttca gcatttctat caggaagctg caccatccca atctgccgtg
6481 gcactcatta ggtatgtcaa ccctgacaca ggcagaaaca tctttgaggc taaattgcac
6541 agggaaggtt tcatcaccgt ggcaaattct ggcaataacc ccattgttgt cccccccaat
6601 gggtatttca ggtttgaagc ttgggtgaat caattttaca ctttgacccc catgggaact
6661 ggtcaggggc gcaggaggaa tcaataatgg ctagtgcttt tcttgcaggt cttgctggcg
6721 acgtcataac aaatggcgtt ggatctctaa taaatgctgg agctaatgca attaatcaga
6781 aagttgaata tgattttaat aaacagcttc aaatggcatc atttaaacat gataaagaga
6841 tgttgcaatc acaagtgttg gcaaccaagc agttgcagca ggagatgatg aacataaggc
6901 agggggtgtt gaccgctggc ggcttctccc ccgcagacgc tgctagaggg gccgtcaacg
6961 ccccaatgac aaagatcctg gactggaatg gcaccaggta ctgggcacca aacagcatga
7021 aaactacaag ctactcagga cagttttcta gcagccctgt tcataagtcc cctgcttcct
7081 cccagcatgt cgctccatca aagggtagat tgcaaaatga ttctgctagt gtatatagct
7141 tcccctcctc tgtttcttca caatcaaccc attcaacagt gctgtcagca ggaactgggt
7201 cttccaggtc catcaccaca tccacaacaa cccctacctt gtctagaacc agcgactggg
7261 ttaggggaca gaatgagagg ctcagcccgt ttatggatgg tgctctccaa actgcctttg
7321 tcacacctcc atcgagcaaa gcttcttcaa atggtacggt ctcaaccgtt cccaaagctg
7381 ttttggactc ctggactcct atgttcaaca cacataggca gcctctcttc gcccacctac
7441 gtaggcgagg ggagtcacaa gtttagtgaa aagagtgatt aggttttctt c
//