Typing tool
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Typing tool
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Complete norovirus genomes
| MW305541 | GII.3 | |
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| GII.P21 |
ORF1: 1..5069
ORF2: 5050..6696
ORF3: 6696..7460
LOCUS MW305541 7479 bp RNA linear VRL 06-JUL-2021
DEFINITION Norovirus GII isolate PNV016867 nonstructural polyprotein (ORF1)
gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete
cds.
ACCESSION MW305541
VERSION MW305541.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7479)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses reveal coexistence of
viral populations evolving under recombination constraints
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7479)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7479
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="PNV016867"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Peru"
/collection_date="14-May-2009"
/note="genotype: GII.3[GII.P21]"
gene <1..5069
/gene="ORF1"
CDS <1..5069
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QPJ58959.1"
/translation="AAANSNNDNAKSSSDGVLSNMAVTFKRALGARSKQPPPRDKPPK
PPRPPTPELVKAIPPPPPNGEDEPIISYNVKEGVSGLPELSTVTQLEESSTAFSVPPL
SQRENRDAKEPLTGTILEMWDGEIYHYGLYVERGLVLGVHKPPAAISLAKVELTPLSL
YWRPVYTPQYLISPDTLRKLHGETFPYTAFDNNCYAFCCWVLDLNDSWLSRRMIQRTT
GFFRPYQDWNRKPLPTMDDSKVKKVANVVLCALSSLFTRPIKDIIGKLKPLNILNILA
TCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAVELVPVVMG
GIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKEEKNELAMV
RSIEDAVLDLEAIENNHMTALLKDKDSLATYMRTLDMEEEKARKLSTKSASPDIVGTI
NALLSRIAAARSLVHRAKEELSSRPRPVVVMISGRPGIGKTHLARELAKKIASSLTGD
QRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCPLTLNCDRIEN
KGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYADAPEVEKAKRDFPGQPDM
WKDTFKPDFTHIKLTLAPQGGFDKNGNTPHGKGVMKTLTASSLVARASGLLHERLDEY
ELQGPTPTTFNFDRNKVLAFRQLAAENKYGLVDTMRVGSQLKNVKTMTELKQALKNIS
VKKCQLVYGGGTYTLESDGKGNVRVEKVNNTSVQTNNELSGALHHLRCARIRYYVKCV
QEALYSILQIAGAAFITTRIAKRMNIQNLWSKPQAEDLEETNNEEGCPKPKNDEEFVI
SSDDIKTEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDR
DKYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERVSLGLVTGSEIRKRNPD
DFKPKGKLWADDDRSVDYNEKLSFEAPPSIWSRIVNFGSGWGFWVSPSLFITSTHVIP
QGAQELFGVPIKQIQVHKSGEFCRLRFPKPIRTDVTGMILEEGAPEGTVATLLIKRPT
GELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGN
DYVVIGVHTAAARGGNTVICATQGNEGEAMLEGGDNKGTYCGAPILGPGNAPKLSTKT
KFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGKPPKPSVLE
AAKKTIINVLEQTIDPPQKWTYAQACASLDKTTSSGHPYHMRKNDCWNGETFTGKLAD
QASKANLMFEEGKNMTPVYTGALKDELVKTDKIYGTIKKRLLWGSDLSTMIRCARAFG
GLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDSTQQRAVLATA
LEIMVKFSPEPHLAQVVAEDLLSPSVMDVGDFKISINEGLPSGVPCTSQWNSIAHWLL
TLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTTKLKEYGLKPTRPDK
TEGPLIISEDLDGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPNHEDPFETMIP
HSQRPIQLMSLLGEAALHGPSFYSRISKLVISELKEGGMDFYVPRQEPMFRWMRFSDL
STWEGDRNLAPSFVNEDGVE"
mat_peptide <1..959
/gene="ORF1"
/product="p48"
mat_peptide 960..2057
/gene="ORF1"
/product="NTPase"
mat_peptide 2058..2594
/gene="ORF1"
/product="p22"
mat_peptide 2595..2993
/gene="ORF1"
/product="VPg"
mat_peptide 2994..3536
/gene="ORF1"
/product="Pro"
mat_peptide 3537..5066
/gene="ORF1"
/product="RdRp"
gene 5050..6696
/gene="ORF2"
CDS 5050..6696
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ58960.1"
/translation="MKMASNDAAPSNDGAAGLVPEINNEAMALEPVAGAAIAAPLTGQ
QNIIDPWIMNNFVQAPGGEFTVSPRNSPGEVLLNLELGPEINPYLAHLARMYNGYAGG
FEVQVVLAGNAFTAGKIIFAAIPPNFPIDNLSAAQITMCPHVIVDVRQLEPVNLPMPD
VRNNFFHYNQGSDSRLRLIAMLYTPLRANNSGDDVFTVSCRVLTRPSPDFSFNFLVPP
TVESKTKPFSLPILTISEMSNSRFPVPIDSLHTSPTENIVVQCQNGRVTLDGELMGTT
QLLPSQICAFRGVLTRSTSRASDQADTATPRLFNYYWHIQLDNLNGTPYDPAEDIPGP
LGTPDFRGKVFGVASQRNPDTTTRAHEAKIDTTSGRFTPKLGSLEISTESDDFDQNKP
TRFTPVGIGVDHEADFQQWTLPDYAGQFTHNMNLAPAVAPNFPGEQLLFFRSQLPSSG
GRSNGILDCLVPQEWVQHFYQESAPSQSQVALVRYINPDTGRVLFEAKLHKLGFITIA
KNGDSPITVPPNGYFRFESWVNPFYTLAPMGTGNGRRRIQ"
gene 6696..7460
/gene="ORF3"
CDS 6696..7460
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ58961.1"
/translation="MAGAFIAGLAGDMFTNTVGSLVNAGANAINQTIDFENNKYLQNA
SFNHDKEMLNAQIEATKRLQADMIAIKQGVLTAGGFSPTDAARGAINAPMTKVLDWNG
TRYWAPGATSTTSMSGGFTNQTVHRSTPNFKTNQAPKPTPSSGSSVRSNSTQITSLSS
HSFGSSRSSGSTVVSSIPSSNRTRDWVNQQNFNLEPHMPGSLRTAFVTPPSSTASSSG
TVSTVSKNVLDSWTSAFNTRRQPLFAHLRRRGESNV"
ORIGIN
1 ccgctgctgc taacagcaac aacgacaacg caaaatcttc aagtgacgga gtattatcta
61 atatggctgt cacttttaaa cgagccctcg gggcgcggtc taaacagccg cccccgaggg
121 acaaaccacc aaaaccccca agaccaccca caccagaact ggttaaagca atcccccctc
181 ccccacccaa cggggaggat gaaccaatca tttcttacaa cgtcaaagag ggtgtttctg
241 gtctgcctga actctcaact gtcactcaac tggaagagag ttctacagca ttcagcgttc
301 cccctcttag tcagagggag aacagagatg caaaggaacc attgactgga accatcctgg
361 agatgtggga cggggagatt taccattatg gcttatacgt ggaacgagga ttagtactag
421 gtgtacacaa accaccagca gccatcagcc ttgccaaggt tgagctgacc cccttgtctt
481 tgtattggag accagtgtac accccacagt acctcatttc ccctgacact ctcaggaagt
541 tgcatgggga gacgttccct tatacagcct ttgacaacaa ctgttatgcc ttctgctgtt
601 gggtgcttga cttgaacgat tcatggctga gcagaaggat gatacagagg actacaggct
661 ttttccgacc ctatcaggac tggaacagga aacccctccc cacgatggat gactccaaag
721 tgaaaaaggt ggccaatgtt gttctctgtg ctctctcatc attgtttaca agaccaatta
781 aggacattat tgggaagttg aaacccctaa acatcctcaa catcctagcc acatgtgatt
841 ggacttttgc aggcatagtg gaatccctga tccttttggc tgaactgttt ggagttttct
901 ggacaccccc agatgtgtct gcaatgatcg ctcccttact gggtgattat gagctgcagg
961 gacccgagga cctcgctgtg gaactcgtac ccgtagtaat gggagggata ggtttggtgc
1021 tgggattcac caaagagaaa atcggcaaaa tgctttcatc tgctgcttca accctgaggg
1081 catgtaaaga tctcggtgca tatgggttgg agatcctcaa gttggtcatg aaatggttct
1141 tcccaaagaa agaagagaaa aacgaattgg caatggtgag atccatcgag gatgcagtgc
1201 tagatcttga ggccattgag aacaaccata tgacagctct actcaaggat aaagacagcc
1261 ttgcaaccta catgaggact cttgacatgg aggaggagaa ggcgaggaaa ctttccacca
1321 agtctgcctc gccggatatt gtgggcacga taaacgccct actgtcaagg attgcagctg
1381 cccggtctct agtgcacagg gctaaggagg agctgtcaag caggccccga ccggttgttg
1441 tgatgatttc agggagacca ggtataggga aaacccatct agctagagag ttggcaaaga
1501 agatcgcctc ctcacttaca ggtgaccaga gggtgggtct tatcccacgc aacggggtcg
1561 accactggga tgcatacaaa ggtgaaagag tcgttctctg ggacgactac gggatgagca
1621 accctatcca tgacgccctc agactccagg agcttgctga cacctgtcct ctcacactca
1681 actgtgacag gattgagaac aaaggcaaag tctttgatag tgatgccata ataataacca
1741 ccaacctggc caacccagcg ccactggatt acgtcaactt tgaagcttgc tcaagacgca
1801 tagacttcct cgtctatgct gatgcccctg aggttgagaa ggctaaacgg gacttcccag
1861 gccaaccaga catgtggaaa gacaccttta aacctgattt cacacacata aaactgacat
1921 tggccccgca aggaggtttt gacaagaatg gtaacactcc tcatgggaag ggtgtcatga
1981 aaaccctcac tgccagttcc ctcgttgccc gagcatcagg gctcctccac gagagattag
2041 acgaatatga gctgcagggc ccaactccca caacattcaa ctttgaccgc aacaaggtgc
2101 ttgcttttag gcaacttgcc gctgaaaaca agtacggtct tgttgacaca atgagggtcg
2161 gatcacagct caaaaatgtc aaaaccatga cagaactcaa acaggctctc aagaatatct
2221 cagtcaagaa atgtcagctt gtgtatggtg ggggcacgta cacacttgaa tctgatggta
2281 aaggtaatgt gcgtgtcgag aaggtgaaca acaccagtgt gcaaactaac aacgagctct
2341 ccggggcttt gcaccatctc aggtgtgcca gaatcaggta ttatgttaag tgtgtccagg
2401 aagctctcta ctccatcttg caaattgccg gggctgcatt tattaccacg cgcattgcaa
2461 agcgcatgaa catacaaaac ctctggtcca aaccacaagc agaagatctg gaggagacta
2521 acaacgagga gggttgtcca aaacctaaaa atgatgagga atttgtcatc tcctctgatg
2581 acatcaaaac cgagggcaaa aaaggaaaga acaaaactgg ccgtggcaag aagcacacag
2641 ccttttccag caaaggactc agtgatgagg agtacgatga gtacaaaaga atcagggagg
2701 agagaaatgg caagtactcc atagaggaat acctacagga cagagacaaa tactatgagg
2761 aggtggccat agccagggca actgaggaag acttctgtga agaagaggag gcaaaaatcc
2821 ggcaaaggat atttagacca acaaggaaac aacgcaaaga ggaaagagtc tctcttggtt
2881 tggttacagg ttctgagatc aggaagagaa acccagatga cttcaaaccc aaagggaaac
2941 tatgggccga tgatgacagg agtgttgact acaatgagaa actcagtttc gaggctccac
3001 caagcatttg gtcacgaata gtcaactttg gctcagggtg gggcttttgg gtctcgccca
3061 gcctcttcat aacatcaacc catgtcattc cccaaggcgc acaggagctc tttggagtgc
3121 ccatcaaaca aatacaagtt cacaagtcag gtgagttctg ccggcttagg ttcccaaaac
3181 caatcaggac agacgtcaca ggcatgatct tggaggaagg tgctccagaa ggcactgttg
3241 ccacacttct catcaagaga ccaactgggg agctcatgcc cttggcagcc agaatgggca
3301 cccacgcaac catgaaaatt cagggtcgca ctgttggtgg acagatgggc atgctactca
3361 cagggtctaa cgctaagagc atggacttgg gcacaactcc tggcgattgt ggttgtccct
3421 atatctacaa gagagggaac gactacgtgg ttattggagt tcacactgcc gccgctcgtg
3481 gaggaaacac cgtcatctgt gcaacccaag gaaacgaggg tgaggccatg ctagaaggtg
3541 gtgacaacaa gggaacttat tgtggagcac caatattagg ccctggaaat gcccccaaac
3601 tcagcaccaa aaccaaattc tggaggtctt ccaccacccc cctgccaccc ggaacctatg
3661 agccagctta tctgggtggc aaggacccta gagtgaaagg tggcccctca ctgcaacagg
3721 ttatgaggga ccaactaaaa ccattcactg agcccagagg caaaccaccc aaaccaagtg
3781 tgctagaagc tgccaagaag actataatca atgtgcttga acaaacaata gacccacctc
3841 aaaaatggac atacgcacag gcgtgtgcat cactagacaa gaccacttcc agcggccacc
3901 cttaccacat gcggaagaac gattgctgga atggggagac tttcacagga aaactggcag
3961 accaagcatc aaaggctaac ctaatgtttg aggaaggaaa gaacatgacc ccagtgtaca
4021 caggagctct gaaagatgag ctagtcaaga ctgataagat ctatgggaca atcaagaaga
4081 gactcctgtg gggttcagac ctatcaacca tgatacggtg tgcacgagcc ttcggtgggc
4141 taatggacga actcaaggcc cattgcgtca cactaccagt tagggttggt atgaacatga
4201 atgaggatgg acccataata tttgagaaac attccagata caaataccat tatgatgcag
4261 attattcccg ctgggactca acacaacaaa gagcagtgct agctacagcc ctggaaataa
4321 tggtcaaatt ctcaccagaa ccccatctgg cccaggtggt tgcagaagac ctcttgtccc
4381 ccagtgtgat ggatgtgggt gatttcaaga tatcaatcaa cgagggatta ccctctggtg
4441 ttccctgcac ctcacaatgg aactccattg cccactggct cctcacacta tgtgcactgt
4501 ctgaagtcac agacctgtcc cctgacatca tccaggcaaa ttccctgttc tccttttatg
4561 gtgatgatga aatagtgagc acagacatca aactggaccc agagaaatta acaacaaaat
4621 tgaaggagta cgggctaaaa ccaacccgtc ctgacaaaac agaaggaccc ttaattatct
4681 ctgaagattt ggatggcctg accttcttac ggagaacggt gacccgtgat ccggccgggt
4741 ggtttggcaa actggaccaa agttcaatac tcagacagat gtactggacc aggggaccaa
4801 accatgagga ccccttcgaa acaatgatac cacactccca aagacccata caactgatgt
4861 cattattggg tgaagccgcg ttgcatggtc catcattcta cagtaggatc agcaaattgg
4921 tcatctcaga attgaaagag ggtggaatgg atttttacgt gcccagacaa gaaccaatgt
4981 tcaggtggat gagattctca gatttgagca cgtgggaggg cgatcgcaat ctggctccca
5041 gttttgtgaa tgaagatggc gtcgaatgac gccgctccat ctaatgatgg tgccgccggc
5101 ctcgtcccag agatcaacaa tgaggcaatg gcgctagagc cagtggcggg tgcagcgata
5161 gcagcacccc tcactggtca gcaaaatata attgatccct ggattatgaa taattttgtg
5221 caagcacctg gtggtgagtt tacagtatcc cctagaaatt cccctggtga agttcttctt
5281 aatttggaat tgggcccaga aataaacccc tatttggccc atcttgctag aatgtataat
5341 ggttatgcag gtggatttga agtgcaggtg gtcctagctg gaaatgcgtt tacagcagga
5401 aagataatct ttgcagcaat tccccccaat tttccaattg acaatctaag tgcagcacag
5461 atcacaatgt gtccacatgt gattgtggat gtcagacagc tggaaccagt caacctcccg
5521 atgcctgacg ttcgcaacaa tttctttcat tacaatcaag ggtctgattc gagattgcgc
5581 ctaattgcaa tgctatatac acctcttagg gcaaataatt ctggggatga tgtttttact
5641 gtgtcttgca gagtgctaac tagacctagc cctgacttct catttaattt ccttgtgcca
5701 cctactgtgg agtcaaagac aaaacccttt tccctcccta ttctgactat ctctgaaatg
5761 tccaattcta ggttcccagt accaattgat tctctgcaca ccagccctac tgagaatatt
5821 gttgtccagt gtcagaatgg gcgcgtcact cttgatggtg agttgatggg cactacccaa
5881 ctcttaccta gccaaatctg tgctttcagg ggcgtgctca ccagatcaac aagcagggct
5941 agtgaccagg ccgatacagc aacccctaga ttgtttaatt attattggca catacaattg
6001 gataatctaa atggaactcc ttatgaccct gcagaagata taccaggccc cctagggaca
6061 ccagatttcc ggggcaaagt ctttggcgtg gccagccaga gaaatcctga tactacaact
6121 agggcacatg aagcaaagat agacacaaca tctggccgct tcaccccaaa attaggctca
6181 ttagagattt ctactgaatc tgatgatttt gatcaaaaca aaccaacaag attcacccca
6241 gttggcattg gggttgacca tgaggcagac tttcaacaat ggactcttcc cgactatgct
6301 ggccagttca cccacaacat gaacttggcc ccagctgttg ctcccaactt ccctggtgag
6361 caactccttt tcttccgctc acagttgcca tcttctggtg ggcgatccaa cgggattcta
6421 gactgcctgg tcccccaaga atgggtacag cacttctacc aagaatcagc cccctcccaa
6481 tctcaagtgg ccctggttag gtatatcaac cctgacactg gtagagtgtt atttgaggcc
6541 aagctgcaca aattaggttt cataactata gccaagaatg gtgactctcc aataaccgtc
6601 cctccaaatg gatattttag gtttgaatct tgggtgaacc ccttttatac acttgccccc
6661 atgggaacag ggaatgggcg tagaagaatt caataatggc tggagctttt atagcaggat
6721 tggctggtga catgttcaca aatactgtag gatctttagt taatgcaggg gctaatgcca
6781 ttaatcaaac aattgatttt gaaaataata aatatttgca aaatgcttct tttaatcatg
6841 ataaggagat gttgaatgca caaattgagg caacaaagag gttacaggct gacatgattg
6901 ctatcaagca aggggttttg accgctggcg gcttctcccc tactgatgca gcccgcgggg
6961 caattaatgc ccccatgaca aaagtcctag attggaatgg aacgagatac tgggcaccag
7021 gtgccacctc cacaacctcg atgtcgggtg gctttacgaa tcaaactgtg cacagatcta
7081 caccaaattt taaaacgaac caggctccca aacccacacc cagcagtgga tcttcagtga
7141 ggtcaaattc aacccaaatc actagcctga gctcacactc gttcgggtcg tctcgatcca
7201 gcgggtctac agttgtcagc tcaataccat cctctaacag gactagggac tgggtcaacc
7261 aacaaaattt taatttggaa ccacacatgc ctggatccct taggacagct tttgtcactc
7321 caccatctag tacagcctct agctcaggca cagtctcaac tgtgtctaaa aatgttttgg
7381 actcctggac atctgcgttt aacacgcgca gacagccgct atttgcacac cttcgcagaa
7441 ggggggagtc aaatgtttag tgaaaagatt attttaaat
//