Typing tool
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Typing tool
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Complete norovirus genomes
| MW305540 | GII.6 | |
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| GII.P7 |
ORF1: 1..5063
ORF2: 5044..6696
ORF3: 6696..7475
LOCUS MW305540 7527 bp RNA linear VRL 06-JUL-2021
DEFINITION Norovirus GII isolate PNV010945 nonstructural polyprotein (ORF1)
gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete
cds.
ACCESSION MW305540
VERSION MW305540.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7527)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses reveal coexistence of
viral populations evolving under recombination constraints
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7527)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7527
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="PNV010945"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Peru"
/collection_date="02-Oct-2008"
/note="genotype: GII.6[GII.P7]"
gene <1..5063
/gene="ORF1"
CDS <1..5063
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QPJ58956.1"
/translation="LGSQNSVNDSINTTPSNKEEAGAFSNIKVGFKKMLGAVPKGTKA
PSSDQHCPTVKIGPKILTVPPEPPNGEDAVQFDAKSETVIGLPDLTTVQNEHENTPYT
VPPLSEREHRPATEPLPGTILEMWDGEFYHYSVYVSGGKALGVHKPPAAISFATIELT
PISLYWRPVYTPSYLVCPDTLKGLAGEKFPYTAFSNNCYNFCCWVLELNDTWLSRRSI
SRTTGFFKPYQSWNRKPLPTVDDGKIKKVANAILCALGSLFSKPIKDLLGKLKPLNLL
HLLASCDWTFAGIVETVILMAELFNVFWTPPDVSNFIASLIGDFELQGPEDLAVELVP
VVMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMKWFFPKKEEKAE
METLRAIEDAVLDMEAIGNNHLTTLLKDKDSLTAFMKTLDLEEEKARKLSTKSSSPDI
VGTINAILARIAAARSLLHKAKEEMFSRIRPVVVMISGRPGIGKTHMARHLAKNIANT
MSGDQRVGLVPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALTLQELADTCPVTLNCD
RIENKGKMFDSDVIIITTNLVNPAPLDYVNFEACSRRIDFLVYAESPEIEKVKRDFPG
QPDMWKDYFKQDFSHIKLTLAPQGGFDKNGNTPHGKGTMRSLTQGSLTARVAGLVHER
KDEFQLQGNDLQTYNFDTNRVSAFRKLAADNKYGIMETMRVGAVLKNVKTLEDLKTAL
RDVRFNECEIIYRNSKYRVSSNGKGSVSVDKVEDHTSQTANEVGSALLRLRQARARYY
VSCFQDLVYTLIQVAGASFVVNRISKRFCWERWVKPTEAQEASEPEKEVAQGRWEIEP
KDTEPEGKKGKNKKGRGKKHTAFSSKGLSDEEYDEFKRIREERNGKYSIEEYLQDRDR
YYEEVAVARATEEDFCEEEEAKIRQRIFRPTRKQRKEERGVLGLVTGSDIRKRRPDDF
QPKGNLWADDTRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSNLLITTTHVLPKG
VKELFGVEVKQIQIHKSGEFCRFRFPRPIRPDVTGLVLEEGAPEGTVCSILIKRPTGE
MIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDCGCPYIYKRGNDI
VVAGVHTAAARGGNTVICATQGQDGEAVLEGNENLGTYCGAPILGPGKAPKLSTKTKF
WRSSPDALPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEPRGKPPRPAVLEEA
KKTVMNVLEQTIDPAKPWTYSQACASLDKTTSSGSPHHVRKNDHWNGESFTGPLADQA
SKANLMYEQAKHVQPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGTMIRCARAFGGL
MDSMKASCIALPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDSTQQRNILSAAME
VMVRFSAEPELAQVVAEDLLAPSQLDVGDFVISVQEGLPSGVPCTSQWNSIAHWILTL
SAMAEVSGLSPDVIQAHSCFSFYGDDEIVSTDINLDPMKLTQKLREYGLVPTRPDKTE
GPLVITEDLTGLTFLRRSIARDPAGWFGKLDQDSILRQLYWTRGPNHENPYESMVPHS
QRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEAMFRWMRFSDLST
WEGDRNLAPEGVNEDGVE"
mat_peptide <1..971
/gene="ORF1"
/product="p48"
mat_peptide 972..2069
/gene="ORF1"
/product="NTPase"
mat_peptide 2070..2588
/gene="ORF1"
/product="p22"
mat_peptide 2589..2987
/gene="ORF1"
/product="VPg"
mat_peptide 2988..3530
/gene="ORF1"
/product="Pro"
mat_peptide 3531..5060
/gene="ORF1"
/product="RdRp"
gene 5044..6696
/gene="ORF2"
CDS 5044..6696
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ58957.1"
/translation="MKMASNDAAPSNDGAANLVPEANNEVMALEPVVGASIAAPVVGQ
QNIIDPWIRENFVQAPQGEFTVSPRNSPGEMLLNLELGPELNPYLSHLSRMYNGYAGG
MQVQVVLAGNAFTAGKIIFAAVPPHFPVDNISAAQITMCPHVIVDVRQLEPVLLPLPD
IRNRFFHYNQENTPRMRLVAMLYTPLRANSGEDVFTVSCRVLTRPAPDFEFTFLVPPT
VESKTKPFTLPILTLGELSNSRFPAAIDMLYTDPNESIVVQPQNGRCTLDGTLQGTTQ
LVPTQICAFRGTLISQTARAVDSTDSPQRARDHPLHVQVKNLDGTQYDPTDDIPAVLG
AIDFKGTVFGVASQRDVSGTQEQGHYATRAHEAHIDTTDPKYAPKLGTILIKSESTDF
NTNQPIRFTPVGMGDNNWRQWELPDYSGRLTLNMNLAPAVSPSFPGERILFFRSVVPS
AGGFGSGYIDCLIPQEWVQHFYQEAAPSQSAVALVRYVNPDTGRNIFEAKLHREGFLT
VANSGNNPIVVPPNGYFRFEAWVNQFYTLAPMGSGQGRRRAQ"
gene 6696..7475
/gene="ORF3"
CDS 6696..7475
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ58958.1"
/translation="MAGAFFAGLAGDVVSNGIGSLINAGANAVNQKVEYDFNKQLQMA
SFKHDKEMLQSQVLATKQLQQEMMNIKQGMLTAGGFSPADAARGAVNAPMTKILDWNG
TRYWAPNSMKTTSYSGQFSSSPVHRSPAPPQHTAPPKGKLQSDSASVYSSPSSVSSQS
THSTVLSAGTGSSRSTPTSTATSTLSRTSDWVRGQNERLSPFMDGALQTTFVTPPSSK
ASSNGTVSTVPKAVLDSWTPMFNTHRQPLFAHLRRRGESQI"
ORIGIN
1 cccttggcag tcaaaattct gtcaatgaca gtatcaacac caccccttca aacaaagaag
61 aggctggtgc attctccaac attaaagttg gatttaagaa aatgctgggt gccgtaccta
121 agggcaccaa agcacccagc agtgaccagc actgtccaac agttaagatc gggcctaaaa
181 tactaacagt cccccctgaa cccccaaatg gtgaagacgc tgtacagttt gatgcaaaat
241 cggaaactgt gattgggcta ccggacttga caacagtgca aaatgaacat gaaaacaccc
301 catacaccgt ccctccactg agtgagaggg aacacagacc agccactgag ccgcttcctg
361 gcacaatatt ggagatgtgg gatggtgagt tctaccacta ctccgtgtac gtcagcggcg
421 gcaaagctct gggggttcac aagcccccgg cagctataag cttcgcgacg atagagctca
481 cccccatatc tctatactgg aggcctgtct acacccccag ctacctggtc tgcccagaca
541 cactgaaagg tctcgctggt gaaaagttcc cctatacggc cttcagcaac aactgctaca
601 acttctgttg ctgggtgctt gagctcaatg acacgtggct cagcagaaga agcatttcca
661 gaaccaccgg cttcttcaaa ccgtaccagt cttggaacag gaaacctctc ccaaccgttg
721 acgatggaaa gatcaaaaag gtggctaacg cgatcctctg tgcactcggt tcgctgttct
781 caaagccaat caaggacctg ttaggcaagc tcaaaccatt gaacttatta cacctgctcg
841 cgtcgtgtga ttggacgttt gcgggtatag tggagacagt catcttaatg gcggaacttt
901 tcaacgtctt ttggaccccg ccagatgtct ctaatttcat agcctccctg ataggtgatt
961 ttgaattgca gggacctgag gacttggcgg tagagcttgt tcctgtggtc atgggtggta
1021 taggaatggt tctcggcttc acagctgaga agataggtcg catgctgtcg tccgctgcat
1081 caacactgcg ggcgtgtaaa gacttaggga actatgctct tgacatactt aaattggtca
1141 tgaagtggtt tttcccaaag aaagaggaga aagccgagat ggagaccttg agggcgattg
1201 aggatgccgt cctagatatg gaggccatag gtaacaacca tctcacgacc ctcctcaagg
1261 acaaagacag tctcacggct ttcatgaaga ccctggatct agaagaagag aaggcaagga
1321 agctatccac caaatcgtcc tcgccggaca tcgtcggcac tatcaatgcc atactggcta
1381 gaatagctgc cgctagatcc ctcctacata aggctaaaga agagatgttc agtaggatca
1441 gaccagtggt tgttatgatc tcaggcagac ctggcattgg caaaacccat atggcaagac
1501 atttggctaa aaacatcgcc aacaccatga gtggtgacca aagagtcggg ctcgttccgc
1561 gcaacggggt tgaccactgg gacgcctaca ggggagagag ggtggtcttg tgggatgatt
1621 atggaatggg gaaccctgtt aaagatgcct taacactaca agaattagct gacacatgcc
1681 cagtcactct aaactgtgac aggatcgaga acaagggaaa aatgttcgac agtgatgtca
1741 tcataattac gaccaatcta gtcaaccctg cacctctcga ttatgtgaac ttcgaggcgt
1801 gctctagaag aattgatttc ttggtctatg cagagtcacc agaaattgag aaggttaaga
1861 gagatttccc tggccaacct gacatgtgga aggactattt caaacaagac ttttcccata
1921 taaagctgac cctagccccc caaggcggat ttgacaagaa tggtaacacc ccgcatggta
1981 agggcaccat gcgatctctc acccaggggt ccctgaccgc aagggttgca ggccttgttc
2041 atgagaggaa ggacgagttc caactacaag ggaatgacct ccagacatac aactttgaca
2101 ccaacagggt ctctgcgttc aggaaactgg ctgcagacaa caagtatgga atcatggaaa
2161 caatgagagt gggtgcagtg ctcaaaaatg tcaaaacttt ggaagatctg aagaccgcct
2221 taagagatgt gaggttcaat gagtgtgaaa taatttacag gaactctaag taccgagtct
2281 cttccaacgg caagggctct gtttctgttg acaaagttga ggatcacacg tcccagactg
2341 caaatgaagt gggctcagca ctccttagac ttagacaagc aagggctaga tattatgtca
2401 gctgtttcca agacctcgtc tacactctca tacaggttgc tggggcatca ttcgttgtca
2461 acaggatctc caaaaggttc tgctgggaaa ggtgggttaa accaaccgaa gcccaagaag
2521 cgagtgagcc tgaaaaggaa gtagctcaag gtagatggga gatagagccc aaggacacag
2581 aaccagaagg caagaagggt aagaacaaga aagggagagg caagaaacac acagccttct
2641 ccagcaaagg cctaagtgat gaagagtatg atgagttcaa gagaatcaga gaagagagga
2701 acggaaaata ctccattgag gaatacctgc aagaccggga ccgctactac gaagaagtgg
2761 cagttgcccg agcaacagaa gaggactttt gtgaagaaga agaagccaag ataagacaaa
2821 gaatcttccg cccgacaagg aagcaaagaa aggaggaaag gggggtgctt ggcttagtca
2881 ctggctcaga tatcaggaag aggagaccag acgattttca accaaaaggt aacctgtggg
2941 cagatgacac taggagtgtg gactacaatg agaggcttga ctttgaggct cccccaagcg
3001 tctggtcaag aatagtccca ttgggtactg gttggggctt ctgggtttca tctaatctcc
3061 tgatcacaac aacacacgtc ctgcccaagg gggtcaagga actctttggg gttgaagtca
3121 aacaaattca aatccacaag tctggagagt tctgcaggtt taggttccca agaccaatca
3181 ggccagatgt cacaggactc gtgttggagg aaggtgctcc agaaggtact gtctgttcta
3241 ttctcataaa gagacctaca ggtgagatga tccccctagc agtgaggatg ggcacgcatg
3301 catccatgaa aatacagggt aggaccgtcg gtggccagat gggaatgctt ctcacagggg
3361 caaacgcaaa gaacatggat cttggcaccg gtcctggtga ctgtggttgc ccttacatct
3421 ataagcgtgg caacgacata gttgtcgcgg gtgtccacac cgcagcagcc cgggggggca
3481 acactgttat ttgtgccact caaggacaag acggggaggc agtccttgag ggaaatgaaa
3541 accttggcac ttactgtggt gctccaattc tgggccctgg caaagcgcct aaactcagca
3601 cgaaaaccaa gttttggcgc tcatcaccag atgccctacc tcctggtacg tatgaacctg
3661 cttacctggg gggtaaggat cccagagtgg aaaaggggcc ctccctacag caagttatga
3721 gggaccagct gaagccattc acagagccca ggggcaaacc acctagacca gcagttttag
3781 aagaggctaa aaagacagtg atgaatgttc tagaacagac cattgaccct gccaaaccat
3841 ggacctactc acaagcatgt gcctcactgg acaagaccac ttctagtgga agcccacacc
3901 atgtcaggaa aaatgaccac tggaatgggg agtcttttac tggtcccctc gcggaccaag
3961 catccaaagc caacctcatg tatgaacagg caaaacatgt gcagcccgtg tacacggccg
4021 cgctcaaaga tgagcttgtt aagactgata agatctacaa gaagataaag aagaggcttc
4081 tatggggatc agaccttggt acgatgatca ggtgtgccag ggcttttggt ggccttatgg
4141 acagtatgaa agcaagttgt atagccctcc catgcagagt ggggatgaac atgaatgagg
4201 atggtcctat catatttgac aaacactcca agtataggta ccattatgat gctgactact
4261 ctaggtggga ctcaacccag caaaggaaca ttctttccgc cgctatggag gtgatggtga
4321 ggttctctgc tgaaccagaa ttggcacaag tggtcgcaga ggacctcttg gcgcccagcc
4381 agctagatgt tggcgatttt gtcatctcag tccaggaggg cctgccatca ggagtcccat
4441 gtacatcaca atggaattca atagcgcact ggattctaac tctgagcgca atggcagaag
4501 tgtcaggcct ttcaccagac gttatccaag cccattcctg cttttcattc tatggcgatg
4561 atgagatcgt cagcactgac atcaaccttg accccatgaa attgacacag aaactcaggg
4621 agtatggtct ggtccccacc cggcctgata agactgaagg ccccctcgtc ataactgaag
4681 acctcaccgg cctgacattc ctgcgtaggt cgattgcacg ggatccagct ggatggtttg
4741 gaaaattgga tcaagactca atcctcaggc aattatactg gacaaggggg cccaatcatg
4801 aaaacccata cgagagcatg gttccccatt cccagcgagc cacccagctc atggcccttc
4861 ttggtgaggc ttcactgcat ggtccccagt tctacaagaa agttagcaag atggtcatca
4921 atgagattaa gagtggtggt ctggagtttt atgtgcccag acaagaggcc atgtttaggt
4981 ggatgagatt ctctgacctc agcacatggg agggcgatcg caatcttgct cccgagggtg
5041 tgaatgaaga tggcgtcgaa tgacgccgct ccatcaaatg atggcgctgc caacctcgta
5101 ccagaggcca acaatgaggt tatggcactt gaaccggtgg tgggagcttc aatcgcagct
5161 cctgttgtcg gtcagcaaaa tataattgac ccctggatta gagaaaattt tgtccaagca
5221 ccacagggcg agtttactgt ttcaccaagg aattcgcccg gtgagatgct cctaaatctt
5281 gaattgggcc cagaactaaa cccctacttg agtcatttgt cccgcatgta caatgggtat
5341 gctggtggta tgcaggttca ggtggtccta gctgggaatg cgttcacagc tgggaagatc
5401 atctttgccg ccgtgccacc acatttcccc gtggacaata ttagtgcagc ccagataact
5461 atgtgccccc atgtgattgt tgatgtgaga cagcttgaac cagtgcttct gcccctcccc
5521 gatataagga acaggttctt ccattacaac caggaaaaca ccccccggat gagacttgtg
5581 gccatgctct acacgcctct aagggctaat tctggagagg acgtgttcac tgtgtcctgt
5641 agggttctga ctcgccccgc tccagatttt gaattcacat ttttagtccc accaactgtt
5701 gaatcaaaaa caaaaccctt tactttacct attctaaccc ttggtgagtt gtctaattcc
5761 cgtttcccgg ctgctataga tatgctttat actgatccca atgaatcaat agttgttcag
5821 ccccaaaatg gtagatgcac ccttgatggc acattgcaag gcacaacaca attggtccca
5881 acacagattt gtgcctttag agggaccctg atcagccaga ctgcgagagc ggtcgattca
5941 acagattccc cccagagagc ccgtgatcac ccgttacacg tccaggtcaa gaacctagat
6001 ggcacacagt atgacccaac agatgatatt cctgcagtcc tgggggctat tgacttcaaa
6061 ggcacagtgt tcggagtggc tagtcagagg gacgtctctg gaacacaaga acagggccat
6121 tatgccaccc gggcccatga agcacacatt gacacaactg acccaaagta tgcgcccaaa
6181 ttaggcacaa ttcttatcaa atctgaatct actgatttta atacaaatca acccattagg
6241 ttcactccag tgggcatggg tgacaacaat tggagacagt gggaattgcc tgactattct
6301 ggtagattga ccctaaatat gaaccttgcc cccgctgttt ccccatcttt ccctggtgaa
6361 cggatccttt tctttaggtc tgtagtacca tcagctggag gcttcgggtc tggctatata
6421 gactgtctca taccccagga atgggtgcaa cacttctacc aggaggcagc accttcacaa
6481 tctgctgttg cactggttag gtatgtcaac cccgacactg ggcgtaacat ctttgaggcc
6541 aagttgcaca gagaagggtt cctcaccgtg gccaattctg gaaacaatcc tattgtggtt
6601 ccccctaatg gttattttag atttgaggct tgggttaatc aattctacac acttgccccc
6661 atgggatctg gacaggggcg tagaagggcc cagtaatggc tggagccttc ttcgcagggt
6721 tagcaggtga tgtcgtgtcg aacggcatcg gttccctcat caatgcaggt gctaatgcag
6781 tcaatcaaaa ggttgagtat gattttaata agcaacttca gatggcatca ttcaaacatg
6841 acaaggagat gttacaatca caggtgttgg caaccaaaca actgcagcag gaaatgatga
6901 atataaaaca ggggatgttg accgctggcg gcttctcccc tgcggacgct gctagagggg
6961 ctgttaacgc tccaatgaca aaaatactgg actggaatgg cacaagatat tgggcaccta
7021 acagcatgaa aactacaagc tattcaggac agttctctag tagccccgtc cacaggtctc
7081 ctgctccccc ccagcacact gctccaccaa aaggtaagtt gcaaagtgat tctgccagtg
7141 tgtatagctc cccttcctct gtttcttcac aatcaaccca ttcaacagtg ttgtctgcag
7201 gaactgggtc gtccagatcc acccccacgt ccacagcaac ctccaccctg tctaggacta
7261 gcgactgggt tagaggacag aatgaaaggc ttagcccgtt tatggatggt gctctccaaa
7321 ctacctttgt cacaccacca tcgagcaaag cttcatcaaa tgggacagtc tcaaccgtgc
7381 ccaaagctgt tttggactcc tggactccta tgttcaatac acataggcag cctctcttcg
7441 cccatttgcg taggcgaggg gagtcacaaa tttagtgaaa agagtgatta ggctttcttt
7501 cccttcctct tccccttttc tctcttt
//