Typing tool
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Typing tool
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Complete norovirus genomes
| MW305536 | GII.3 | |
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| GII.P16 |
ORF1: 1..5066
ORF2: 5047..6693
ORF3: 6693..7457
LOCUS MW305536 7511 bp RNA linear VRL 06-JUL-2021
DEFINITION Norovirus GII isolate ONVHH0778 nonstructural polyprotein (ORF1)
gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete
cds.
ACCESSION MW305536
VERSION MW305536.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7511)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses reveal coexistence of
viral populations evolving under recombination constraints
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7511)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7511
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="ONVHH0778"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Peru"
/collection_date="17-Sep-2013"
/note="genotype: GII.3[GII.P16]"
gene <1..5066
/gene="ORF1"
CDS <1..5066
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QPJ58944.1"
/translation="VACNNNNDKEKSSGEGLFTNMSSTLKKALGARPKQPAPRDNPQK
PPRPPTPELVKGIPPPPPNGEEEEPVIRYEVKSGISGLPELTTVPQPDVANTAFSVPP
LSLRENREAKEPLTGAILEMWDGEIYHYGLYVEKGLVLGVHKPPAAISMAKVELTPLS
LYWRVVYTPQYLISPETLRRLNGEAFPYTAFDNNCYAFCCWVLDLNDSWLNRRMVQRT
TGFFRPYQEWNRKPLPTMDDSKIKKVANIFLCSLSTLFTRPIKDLIGKIKPLNILNIL
ATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAVELVPVVM
GGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKEEANELAM
VRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMKTLDMEEEKARRLSTKSASPDIVGT
INALLARIAAARSLVHRAKEELSSRIRPVVVMISGKPGIGKTHLAREVARKVASTLTG
DQRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRIQELADTCPLTLNCDRIE
NKGKVFDSEVIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAKRDFPGQPD
MWKDAFKSDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGLLHERMDE
FELQGPTVTTFNFDRNRITAFRQLAAENKYGLVDTMRVGNQLKGVKTMEELKQAIKNV
IIKRCRIIYGGSTYDLESDGKGKVLVEKVKNTSVQTNNELAGALHHLKHARIRYYVRC
VQEAVYSIIQIAGAAFVTTRIARRMNIQELWSKPPLDQNESEAKEEAPKSEDGEFIIS
SKDIKEEGKKGKNKTGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDRD
RYYEELAIAKATEEDFCEEEEIKIRQRIFRPTRKQRKEERATLGLVTGSEIRKRNPDD
FKPKGKLWADDNRSVDYNEKLDFEAPPSIWSRIVSFGSGWGFWVSPSLFITSTHVIPA
GITEAFGVPIKQIQVHKSGEFCRFRFPKPIRPDVTGMILEEGAPEGTVATVLIKRPTG
ELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKGMDLGTTPGDCGCPYIYKRGND
YIVIGVHTAAARGGNTVICATQGSEGEATLEGGDDKGTYCGAPILGPGGAPKLSTKTK
FWRSSNTPLPPGTYEPAYLGGRDPRVKGGPSLQQVMRDQLKPFTEPRGKPPRPSVLEA
AKQTIINVLEQTLDPPQKWTYAQACASLDKTTSSGHPHHVRKNECWNGETFTGKLADQ
ASKANLMFEEGKHMTPVYTAALKDELVKTDKVYGKIKKRLLWGSDLSTMIRCARSFGG
LMDEMKAHCISLPVRVGMNMNEDGPIIFEKHSRYKYHYDADYSRWDSTQQRAVLASAL
EIMVRFSAEPQLAQIVAEDLLAPSVVDVGDFKISINEGLPSGVPCTSQWNSIAHWLLT
LCALSEVTKLSPDIIQANSMFSFYGDDEIVSTDIKLDPEKLTTKLKEYGLKPTRPDKT
EGPLIISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQMYWTRGPNHEDPSETMIPH
SQRPIQLMALLGEASLHGPSFYSKISKLVITELKEGGMDFYVPRQEPMFRWMRFSDLS
TWEGDRNLAPNFVNEDGVE"
mat_peptide <1..962
/gene="ORF1"
/product="p48"
mat_peptide 963..2060
/gene="ORF1"
/product="NTPase"
mat_peptide 2061..2591
/gene="ORF1"
/product="p22"
mat_peptide 2592..2990
/gene="ORF1"
/product="VPg"
mat_peptide 2991..3533
/gene="ORF1"
/product="Pro"
mat_peptide 3534..5063
/gene="ORF1"
/product="RdRp"
gene 5047..6693
/gene="ORF2"
CDS 5047..6693
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ58945.1"
/translation="MKMASNDAAPSNDGAAGLVPEINNEAMALDPVAGAAIAAPLTGQ
QNIIDPWIMNNFVQAPGGEFTVSPRNSPGEVLLNLELGPEINPYLAHLARMYNGYAGG
FEVQVVLAGNAFTAGKVIFAAIPPNFPTDNLSAAQITMCPHVIVDVRQLEPINLPMPD
VRNNFFHYNQGSDSRLRLIAMLYTPLRANNSGDDVFTVSCRVLTRPSPDFSFNFLVPP
TVESKTKPFSLPILTISEMSNSRFPVPIDSLHTSPTDNIVVQCQNGRVTLDGELMGTT
QLLPSQICAFRGVLTRSTSRVSDQADTATPRLFNYYWHIQLDNLNGTPYDPAEDIPAP
LGTPDFRGKVFGVASQRNPDSTTRAHEAKVDTTSGRFTPKLGSLEISTESDDFDQNQP
TRFTPVGIGVDNEADFQQWTLPDYSGQFTHNMNLAPAVAPNFPGEQLLFFRSQLPSSG
GRSNGILDCLVPQEWVEHFYQESAPAQTQVALVRYVNPDTGRVLFEAKLHKLGYMTIA
KSGDSPITVPPNGYFRFESWVNPFYTLAPMGTGNGRRRIQ"
gene 6693..7457
/gene="ORF3"
CDS 6693..7457
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ58946.1"
/translation="MAGAFIAGLAGDMLTNTVGSLVNAGAGAINQKVDFENNKYLQNA
SFNHDKEMLNAQIEATKRLQADMIAIKQGVLTAGGFSPTDAARGAINAPITKVLDWSG
TRYWAPNATSTTSMSGGFTGQAVHRATPNFTTNQAPKPTPSSGSSVRSNSTQLTNLSS
HSSGSSRSSGSTMVSSLPSSSRTRDWVNQQNFNLEPHMPGSLRTAFVTPPSSTASSLD
TVSTVPKSVLDSWTSAFNTRRQPLFAHLRRRGESNV"
ORIGIN
1 ccgttgcttg caacaacaac aacgacaagg aaaagtcttc aggtgaaggc ttattcacaa
61 atatgtcttc caccttaaag aaagccctcg gggctcggcc taaacagccc gccccgaggg
121 acaacccaca aaagcctcca agaccaccaa ctcccgagtt ggtcaagggg ataccccctc
181 ccccacctaa tggtgaagaa gaagaaccag tcattaggta tgaggttaag agtgggatct
241 ctggcctgcc cgagctcaca acagtccccc aaccggatgt ggccaacacg gcattcagtg
301 tcccaccgct gagcttgaga gaaaacaggg aggccaagga accgctgaca ggggcaatat
361 tagagatgtg ggatggagaa atataccact atggcttgta cgtggagaaa ggcttagtgt
421 tgggtgtgca caaaccacct gcagctataa gcatggcaaa agtggagctg acgccgttgt
481 cattgtactg gcgtgtggtc tacacccccc aatacctcat ctcccctgaa actctcagga
541 ggctcaacgg agaggcattc ccttacaccg cctttgacaa caactgctat gccttttgct
601 gctgggtatt agacctcaat gactcatggc ttaacaggag gatggtgcaa aggacaacag
661 gcttcttcag accttaccaa gagtggaaca gaaaacccct gcctactatg gatgactcca
721 aaatcaagaa ggtggcaaat atatttctgt gttcattgtc cacgctgttc accagaccta
781 taaaagatct cataggaaaa attaaaccat taaatatctt gaacatcctg gcaacgtgtg
841 actggacgtt cgccggaata gtggagtctt tgatattact cgctgaactc tttggagttt
901 tctggacacc cccagatgtg tctgctatga tcgctccctt acttggagac tacgagttgc
961 aagggccaga agacctcgcc gttgagctcg tacctgtggt aatgggaggg attggtttgg
1021 tgctgggatt caccaaagag aaaattggca aaatgttgtc ctcagcagca tcaacgctca
1081 gggcttgtaa agatcttggt gcctatggct tagagatact caaattggtc atgaagtggt
1141 tcttcccgaa gaaagaagag gccaatgagc tagccatggt gagagctata gaggatgctg
1201 tactggatct tgaggcgata gaaaataatc acatgacaac tctgttgaaa gacaaagaca
1261 gcctagcaac ctacatgaaa acactggaca tggaggagga aaaagccaga agattgtcca
1321 caaaatctgc atcccctgac atagttggga cgatcaacgc cctgctggct cgaatagcag
1381 cggctaggtc actagtccac agggccaagg aggagttatc tagcaggata agaccagtgg
1441 ttgttatgat atctggcaag ccagggatag gcaagactca tttggccagg gaggtggcga
1501 gaaaggtggc atccactctc acaggggatc aaagagtcgg gctcataccg agaaacggtg
1561 tggaccattg ggatgcatac aaaggtgaga gagtcgtgct gtgggacgac tatggcatga
1621 gcaaccccat tcatgatgct ctgcgcatac aagaattggc tgatacgtgt ccccttacct
1681 tgaattgtga cagaattgaa aataagggaa aagtttttga cagtgaagtc ataataatta
1741 caacaaacct tgccaatcca gctccacttg attatgtcaa ctttgaggcc tgttccagga
1801 gaattgactt cctggtgtac gccgaggcac cagaagtaga aaaggcaaag cgagactttc
1861 ctggtcaacc agatatgtgg aaggacgcct tcaagtcgga cttttcacat atcaagttgc
1921 aacttgcacc tcagggcggc tttgacaaga atggtaacac cccacatggg aaaggagtga
1981 tgaagaccct caccactggt tcccttattg cccgtgcatc aggcttactg catgagagga
2041 tggatgaatt tgaactccaa ggccccacag tcaccacctt caatttcgac cggaacagaa
2101 tcaccgcatt cagacaattg gctgcagaaa acaagtatgg gttagtggac accatgagag
2161 ttggcaatca attaaaaggg gtgaaaacca tggaagaact caaacaagca atcaaaaatg
2221 tgatcatcaa gaggtgccga atcatctacg gtggctcaac gtatgacctt gaatctgatg
2281 gcaagggcaa agttttggtg gaaaaggtaa agaatacctc tgtgcagacc aacaacgagt
2341 tggccggagc cctgcaccac ctcaaacatg cccgaatcag gtactatgtc agatgcgtgc
2401 aagaagcagt ctactctatc atacaaatcg ctggcgctgc gtttgtaacc acacgcattg
2461 cacgccgcat gaacatacaa gaactttggt cgaagccacc attagaccaa aatgagtcag
2521 aggctaagga agaggccccc aagtcagaag atggcgagtt catcatatct tctaaggaca
2581 tcaaggagga aggaaagaag ggcaaaaaca aaactggccg tggcaagaaa cacacagcat
2641 tctctagcaa gggtttgagc gatgaggagt atgacgagta caagaggata agagaagaga
2701 gaaatgggaa gtactccata gaggagtacc ttcaagacag agacaggtac tatgaggaac
2761 tcgccatcgc caaggccacg gaagaagatt tctgtgagga ggaggagatc aagatccgtc
2821 agaggatctt ccgtcccacc aggaaacaaa ggaaggaaga gagggccaca ctagggctag
2881 taactggttc agaaatcaga aaaagaaacc ctgatgactt caaacctaaa gggaaactgt
2941 gggccgatga taacagaagt gttgactaca atgagaaact ggactttgag gcccccccaa
3001 gcatatggtc taggattgtg agctttggtt ctggctgggg cttttgggta tcaccaagcc
3061 tgttcataac atcaactcat gtaatccctg caggcataac agaggcattt ggagtcccca
3121 tcaagcaaat ccaggtccac aaatcaggtg aattttgccg gttcaggttc ccaaaaccaa
3181 ttagaccaga tgtgacagga atgatcttgg aagaaggtgc gcctgagggc actgtggcaa
3241 ccgtgctcat caaacgccct accggagaac tcatgcccct tgcagccaga atggggacac
3301 acgcaaccat gaaaattcaa ggccgcatgg ttggcggaca gatgggtatg ttgctcactg
3361 gttcaaatgc taaagggatg gatttgggaa caactcctgg tgactgtggc tgtccctaca
3421 tctacaagag gggcaatgac tatatagtca ttggggtgca tacagcagca gcccgtggtg
3481 gaaacaccgt catctgtgcc acacagggaa gtgagggtga ggcaactctt gaaggtggag
3541 atgacaaagg aacatattgt ggggcaccca ttctaggccc tggaggggca ccaaaattga
3601 gcaccaaaac caaattttgg aggtcatcga acacgcctct tccaccaggg acatatgagc
3661 ctgcctacct cggtggccgt gacccgcgtg tcaagggtgg accctcccta cagcaggtaa
3721 tgagagacca gttgaagcca ttcactgagc ccaggggtaa acctccaaga ccaagtgtgt
3781 tggaagcagc caaacaaacc atcatcaatg tcctcgaaca aaccctggac cccccacaaa
3841 aatggactta cgcacaggcg tgtgcttcac ttgacaaaac cacctccagc gggcatcccc
3901 atcacgtccg gaagaatgaa tgctggaacg gtgagacctt cactggtaaa ttggcagacc
3961 aagcatcaaa agcaaatcta atgtttgagg aagggaaaca catgacacca gtgtacacag
4021 cagccctcaa ggacgagttg gtcaagactg acaaagtcta tggaaagatc aaaaagagac
4081 tgctctgggg ctctgactta tccaccatga tccggtgcgc caggtccttt ggtgggctca
4141 tggatgagat gaaggcacac tgcatatcac tcccagtccg agtaggcatg aacatgaatg
4201 aagatggtcc aataatattt gagaagcact ccagatacaa gtaccattat gatgcagact
4261 actcccgctg ggattcaaca caacagagag cagtattagc atcagccttg gaaatcatgg
4321 tcaggttctc tgcagagcca caactggcac agatagtcgc tgaggatctg ttggccccca
4381 gtgtggtaga tgtaggagac tttaaaattt caataaatga agggctccct tctggtgtac
4441 catgcacttc tcaatggaac tccatcgcac actggctact aactctctgt gccttgtctg
4501 aagtcaccaa actgtcccct gacattatac aggcaaattc catgttctca ttctacggtg
4561 atgacgagat tgtcagcacc gatataaaat tggaccctga aaagttaacc accaaattga
4621 aagagtacgg cctgaaacca actcgcccag acaaaaccga gggacccctg atcatcagtg
4681 aggatttgaa cggactcact ttcctccgaa ggacggtgac tcgtgaccca gctggctggt
4741 ttggaaaatt ggaccaaagt tcaatattga ggcagatgta ctggactaga ggaccaaatc
4801 atgaagatcc cagtgagaca atgatacccc actctcaaag acccatacag ctcatggcat
4861 tgcttggtga ggcctccctt cacggaccct ctttctatag caagattagt aaattggtca
4921 taactgaact caaagaaggt gggatggact tttacgtgcc aaggcaggaa cccatgttca
4981 ggtggatgag gttttctgat ttgagcacgt gggagggcga tcgcaatctg gctcccaatt
5041 ttgtgaatga agatggcgtc gaatgacgct gctccatcta atgatggtgc cgccggcctc
5101 gtaccagaga tcaataatga ggcaatggcg ctagatccag tggcgggtgc agcgatagca
5161 gcacccctta ctggccagca aaacataata gatccctgga ttatgaataa ttttgtgcaa
5221 gcacctggtg gtgagtttac agtgtcacct aggaactccc ctggtgaagt acttctaaat
5281 ttagaattag gcccagaaat aaatccctat ctggcgcatc ttgctaggat gtacaatggt
5341 tatgcaggtg ggtttgaggt gcaggtggtc ctggctggaa acgcgtttac agcagggaaa
5401 gtgatctttg cagctatacc ccccaatttt ccaactgaca atttgagtgc agcacagatc
5461 acaatgtgtc ctcatgtaat tgtggatgtc agacagttgg aaccaatcaa cctcccgatg
5521 cctgatgtcc gcaacaattt cttccattac aatcaaggtt ctgattcgag gttacgctta
5581 attgcaatgt tgtatacacc ccttagggca aataattctg gagatgatgt tttcactgtg
5641 tcatgtaggg tattgactag gcccagtcct gatttttcat ttaatttcct cgtcccgccc
5701 actgtggaat caaagacaaa acctttttcc ctccctattt tgactatctc tgagatgtct
5761 aattctagat ttccagtgcc aattgattct ctgcacacca gtccaactga taacattgtt
5821 gttcagtgcc aaaatgggcg cgtcaccctt gacggtgagc taatgggcac cactcaactc
5881 ttgccgagtc agatatgtgc ttttaggggt gtgctcacca gatcaacaag cagggtcagt
5941 gaccaagctg acacagcaac ccccagactc ttcaactact actggcacat acaactagac
6001 aacctaaatg ggaccccgta tgatcctgca gaggacatac cagcccctct ggggacgcca
6061 gactttcggg gcaaagtctt tggcgtagcc agccagagaa accctgacag cacaacgagg
6121 gcacatgagg caaaagtgga cacaacatct ggccgcttca ccccaaaatt gggctcccta
6181 gaaatatcca ctgaatctga tgactttgac caaaaccaac caacaagatt caccccagtt
6241 ggcattggag ttgacaacga ggcagacttt caacaatgga ccttacccga ctattctggt
6301 cagttcaccc acaacatgaa tctggcccca gctgtcgctc ccaattttcc cggtgaacag
6361 ctgcttttct tccgctcaca gttgccatcc tctggcgggc ggtccaatgg cattctagac
6421 tgcttggtcc cccaggaatg ggtcgaacat ttctaccagg agtccgcccc tgcccaaacg
6481 caggtggctc tggtcaggta tgtcaaccct gatactggta gggtgttatt tgaggctaag
6541 ctgcataagc taggctacat gaccatagct aagagtggtg attctccaat aactgtaccc
6601 ccaaatggat actttaggtt tgaatcttgg gtgaacccct tttacacatt agcccccatg
6661 ggaactggga atgggcgcag aaggatccaa taatggctgg agcctttata gcaggattgg
6721 ctggtgacat gctcacaaac actgtagggt ctttagttaa tgcaggggct ggtgctatta
6781 atcaaaaggt tgattttgaa aataataaat atttacaaaa tgcatctttc aatcatgata
6841 aggagatgtt aaatgcacaa attgaggcaa caaagaggtt gcaggctgac atgattgcta
6901 tcaaacaagg ggttttgacc gctggcggtt tttcccccac tgatgcagcc cgtggggcta
6961 ttaatgcccc cataacaaaa gttctggact ggagtggaac caggtactgg gcaccaaatg
7021 ccacctccac tacttcaatg tcaggtggct tcacaggtca agctgtgcac agagctacac
7081 caaattttac aaccaatcaa gccccaaaac ccacacccag cagtgggtct tcagtgaggt
7141 caaactcaac ccaactcacc aatttgagct cacactcatc tgggtcttct cgatccagcg
7201 gatccacgat ggtcagctcg ttaccatctt ccagtagaac tagagactgg gttaaccaac
7261 agaattttaa tttggaacca cacatgcctg gatctctcag gacagctttt gtcactccac
7321 catctagtac agcctctagc ttagacacgg tctcaaccgt gcccaagagt gttttggact
7381 cctggacatc tgcgtttaac acgcgcagac agccgctttt cgcacacctt cgtagaaggg
7441 gggagtcaaa tgtttagtga aaagattgtt tttaaatttg gtttgtaatt ggatttaaat
7501 tagaatcttt t
//