Typing tool
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Typing tool
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Complete norovirus genomes
| MW305535 | GII.4 Sydney | |
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| GII.P31 |
ORF1: 1..5069
ORF2: 5050..6672
ORF3: 6672..7478
LOCUS MW305535 7525 bp RNA linear VRL 18-JUL-2024
DEFINITION Norovirus GII isolate ONVHH0051 nonstructural polyprotein (ORF1)
gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete
cds.
ACCESSION MW305535
VERSION MW305535.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7525)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A.U.A., Ford-Siltz,L.A., Green,K.Y.,
Galeano,M.E., Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N.,
Ushijima,H. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses provide insights on
evolutionary dynamics and evidence of coexisting viral populations
evolving under recombination constraints
JOURNAL PLoS Pathog 17 (7), e1009744 (2021)
PUBMED 34255807
REMARK Publication Status: Online-Only
REFERENCE 2 (bases 1 to 7525)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7525
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="ONVHH0051"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Peru"
/collection_date="03-Jun-2013"
/note="genotype: GII.4[GII.P31]"
gene <1..5069
/gene="ORF1"
CDS <1..5069
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QPJ58941.1"
/translation="AVANSNNDIAKSSSDGVFSNMAVTFKRALGARPKQPPPKETPPR
PPRPPTPELVKKIPPPPPNGEDELVVSYSAKDGVSGLPELTTVRQPEETNTAFSVPPL
NQRESRDAKEPLTGTIIEMWDGEIYHYGLYVERGLILGVHKPPAAISLAKVELTPLSL
FWRPVYTPQYLISPDTLRRLHGESFPYTAFDNNCYAFCCWVLDLNDSWLSRRMIQRTT
GFFRPYQDWNRKPLPTMDDSKLKKVANIFLCTLSSLFTRPIKDIIGKLKPLNILNILA
TCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDYELQGPEDLAVELVPIVMG
GIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKEEANELAMV
RSIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKSASPDIVGTI
NSLLARIAAARSLVHRAKEELSSRPRPVVVMISGRPGIGKTHLARELAKKIAASLTGD
QRVGLIPRNGVDHWDAYKGERVVLWDDYGMSNPIHDALRLQELADTCPLTLNCDRIEN
KGKVFDSDAIIITTNLANPAPLDYVNFEACSRRIDFLVYAEAPEVEKAKRDFPGQPDM
WKNAFSPDFSHIKLSLAPQGGFDKNGNTPHGKGVMKTLTTGSLIARASGLLHERLDEY
ELQGPALTTFNFDRNKILAFRQLAAENKYGLMDTMRVGKQLKDVKTMSDLKQALKNIA
IKKCQIVYNGSTYTLEADGKGSVKVDKVQSATVQTNNELAGALHHLRCARIRYYVKCV
QEALYSIIQIAGAAFVTTRIAKRMNIQNLWSKPQVEDTEEMANKDGCLKPKDDEEFVV
SSDDIRTEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYLQDR
DRYYEEVAIARATEEDFCEEEEAKIRQRIFRPTRKQRKEERASLGLVTGSEIRKRNPE
DFKPKGKLWADDDRSVDYNEKLNFEAPPSIWSRIVNFGSGWGFWVSPSLFITSTHVIP
QGAKEFFGVPIKQIQIHKSGEFCRLRFPKPIRTDVTGMILEEGAPEGTVATLLIKRPT
GELMPLAARMGTHATMKIQGRTVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYKRGN
DYVVIGVHTAAARGGNTVICATQGSEGEATLEGGDSKGTYCGAPILGPGSAPKLSTKT
KFWRSSTTPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGKPPRPNVLE
SAKKTIINVLEQTIDPPQKWSFAQACASLDKTTSSGHPHHMRKNDCWNGESFTGKLAD
QASKANLMFEEGKNMTPVYTGALKDELVKTDKVYGKIKKRLLWGSDLATMIRCARAFG
GLMDELKAHCVTLPVRVGMNMNEDGPIIFEKHSRYRYHYDADYSRWDSTQQRDVLAAA
LEIMVKFSPEPHLAQVVAEDLLSPSVMDVGDFQISISEGLPSGVPCTSQWNSIAHWLL
TLCALSEVTDLSPDIIQANSLFSFYGDDEIVSTDIKLDPEKLTAKLKEYGLKPTRPDK
TEGPLVISEDLDGLTFLRRTVTRDPAGWFGKLEQSSILRQMYWTRGPNHEDPFETMIP
HSQRPIQLMSLLGEAALHGPAFYSKISKLVIAELKEGGMDFYVPRQEPMFRWMRFSDL
STWEGDRNLAPSFVNEDGVE"
mat_peptide <1..959
/gene="ORF1"
/product="p48"
mat_peptide 960..2057
/gene="ORF1"
/product="NTPase"
mat_peptide 2058..2594
/gene="ORF1"
/product="p22"
mat_peptide 2595..2993
/gene="ORF1"
/product="VPg"
mat_peptide 2994..3536
/gene="ORF1"
/product="Pro"
mat_peptide 3537..5066
/gene="ORF1"
/product="RdRp"
gene 5050..6672
/gene="ORF2"
CDS 5050..6672
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ58942.1"
/translation="MKMASSDANPSDGSAANLVPEVNNEVMALEPVVGAAIAAPVAGQ
QNVIDPWIRNNFVQAPGGEFTVSPRNAPGEILWSAPLGPDLNPYLSHLARMYNGYAGG
FEVQVILAGNAFTAGKVIFAAVPPNFPTEGLSPSQVTMFPHIVVDVRQLEPVLIPLPD
VRNNFYHYNQSNDPTIKLIAMLYTPLRANNAGDDVFTVSCRVLTRPSPDFDFIFLVPP
TVESRTKPFSVPVLTVEEMTNSRFPIPLEKLFTGPSSAFVVQPQNGRCTIDGVLLGTT
QLSPVNICTFRGDVTHVTGSHNYTMNLASQNWNNYDPTEEIPAPLGTPDFVGKIQGVL
TQTTRTDGSTRGHKATVYTGSADFAPKLGRVQFETDTDRDFEANQNTKFTPVGVIQDG
STTHQNEPQQWVLPSYSGRNTHNVHLAPAVAPTFPGEQLLFFRSTMPGCSGYPNMVLD
CLLPQEWVQFFYQEAAPAQSDVALLRFVNPDTGRVLFECKLHKSGYVTVAHTGQHDLV
IPPNGYFRFDSWVNQFYTLAPMGNGTGRRRAV"
gene 6672..7478
/gene="ORF3"
CDS 6672..7478
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ58943.1"
/translation="MAGAFFAGLASDVLGSGLGSLINAGAGAINQKVEFENNRKLQQA
SFQFSSNLQQASFQHDKEMLQAQIEATKKLQQEMMKVKQAMLLEGGFSETDAARGAIN
APMTKALDWSGTRYWAPDARTTTYNAGRFSTPQPSGAQPGRANLREAVPARGSSSKSS
NSSTATSVYSNQTTSTRLGSTAGSGTSVSSLPSTARTRSWVEDQSRNLSPFMRGAHNI
SFVTPPSSRSSSQGTVSTVPKEILDSWTGAFNTRRQPLFAHIRKRGESRV"
ORIGIN
1 ccgctgttgc caacagcaac aacgacatcg caaaatcttc aagtgacggt gtgttttcta
61 acatggctgt cacttttaag cgggccctcg gggcgcggcc taaacagccg cccccgaagg
121 agacaccacc cagacccccg cgaccaccca caccagaatt ggtcaaaaag atccctcctc
181 ccccacccaa cggggaggat gaactagtgg tctcttacag cgccaaagat ggcgtttccg
241 gactgcctga gctcaccact gtcagacaac cggaagaaac caacacggcg ttcagtgtcc
301 ccccactcaa ccaaagggag agcagggacg ccaaggagcc actaactgga acaattattg
361 aaatgtggga tggagaaatc taccattacg gcctgtacgt ggaaagaggt cttatacttg
421 gtgtgcacaa gccaccggca gccatcagcc ttgccaaggt cgagctaaca ccgctctctt
481 tgttctggag acctgtatac accccccagt atctcatctc tccagacact cttaggaggt
541 tacatgggga gtcattcccc tacactgcat ttgacaacaa ttgctacgcc ttttgttgtt
601 gggtattaga cctaaacgac tcatggctaa gcaggagaat gattcagaga acaacaggtt
661 tcttcaggcc gtaccaggat tggaacagga aacccctccc caccatggat gattccaaat
721 taaagaaggt agccaacata ttcttgtgca ctttgtcttc actattcacc agacccatta
781 aggacataat agggaaattg aaacctctta acatccttaa cattctggct acatgtgatt
841 ggaccttcgc aggcatagtg gaatctttaa tactcttagc agaactcttt ggagttttct
901 ggacaccccc agatgtgtct gcgatgatcg cccccttgct aggtgattat gaactgcaag
961 gacctgagga ccttgcagtg gaactggtcc caatagtgat gggggggata ggtttggtgc
1021 taggatttac caaagagaaa attggaaaga tgctatcatc cgctgcatcc actttaagag
1081 cttgtaaaga ccttggtgca tacggactgg aaatcttaaa attggtcatg aagtggttct
1141 tcccaaagaa agaggaagca aatgaactgg ctatggtaag atccatcgag gatgcggtgc
1201 tagacctcga ggcaattgaa aacaaccaca tgaccaccct actcaaagac aaagacagct
1261 tggcaaccta catgagaacc cttgaccttg aggaggagaa agccagaaaa ctctcaacca
1321 aatctgcttc acccgatatt gtgggcacaa tcaactctct tctggcaaga atcgctgctg
1381 cacgctccct agtgcatcgg gcgaaagaag agctctccag caggccgaga cctgtcgttg
1441 tgatgatatc gggaagacca gggataggga aaactcacct tgctagggag ctggccaaga
1501 agatcgcggc ctccctcaca ggggaccagc gtgtgggtct tatcccacgc aatggtgtcg
1561 atcactggga cgcgtacaag ggcgaaagag ttgtcctatg ggacgactat ggaatgagca
1621 accccatcca tgatgccctc aggctgcagg agcttgctga cacttgcccc ctcacgctaa
1681 attgtgacag aattgagaat aaagggaaag tctttgacag tgatgccata attatcacca
1741 ccaatctggc caacccagca ccactggatt atgtcaactt tgaagcgtgc tcgagacgta
1801 ttgacttcct cgtgtacgca gaagcccctg aggtggagaa ggcaaagcgc gacttcccag
1861 gtcaacctga catgtggaag aacgctttca gtcctgactt ctcacacata aaactgtcat
1921 tggctccaca gggtggtttt gacaagaacg gcaacacccc gcatggaaaa ggggtcatga
1981 agaccctcac cactggctcc ctcatcgccc gagcatcagg gttactccat gagaggctag
2041 atgaatatga actgcaaggc ccagccctca ccactttcaa ctttgaccgc aacaagatac
2101 ttgcttttag acagcttgct gctgaaaaca agtatgggct gatggacaca atgagagttg
2161 gaaaacagct caaggatgtc aagaccatgt cagacctcaa acaagcactc aagaacatcg
2221 cgatcaagaa gtgccagata gtgtacaatg gtagcaccta cacacttgag gccgatggca
2281 agggtagtgt gaaagttgac aaagtgcaaa gtgccactgt gcagaccaac aatgaattag
2341 ccggtgccct acaccaccta aggtgcgcta gaatcagata ttatgttaaa tgcgtccagg
2401 aggcactgta ttccatcatc caaatcgctg gggctgcatt cgtcaccacg cgcatcgcta
2461 agcgcatgaa tatacagaat ctctggtcca agccacaggt ggaagacaca gaagagatgg
2521 ccaacaaaga tggttgccta aaacccaaag atgatgaaga gtttgtcgtc tcatccgacg
2581 acatcagaac tgagggcaag aaagggaaga acaagtccgg ccgtggcaag aagcacacag
2641 ccttttcaag caaagggctc agtgatgagg agtacgatga gtacaagaga atcagagaag
2701 aaaggaatgg taagtactcc atagaagagt accttcagga cagagacagg tactacgagg
2761 aggtggccat tgccagggca accgaagagg acttctgtga agaagaagag gccaaaatcc
2821 ggcagagaat ttttagacca acaaggaaac aacgcaaaga agagagggcc tctctcggat
2881 tggtcacagg ctctgaaatc aggaagagaa acccagaaga cttcaaaccc aagggaaaac
2941 tgtgggctga tgatgacaga agtgttgact acaacgagaa actcaacttt gaggccccac
3001 caagcatttg gtcgcggata gtcaactttg gttcaggctg gggcttctgg gtctccccca
3061 gtctgtttat aacatcaacc catgtcatac cccaaggtgc aaaagagttc ttcggagtcc
3121 ctatcaagca aatccagata cacaaatcag gtgaattctg ccggttgaga ttcccaaagc
3181 caatcagaac tgatgtgacg ggcatgattc tagaagaagg tgcgcccgag ggaaccgtgg
3241 ccacactgct catcaagaga ccaactggag agctcatgcc tctggcagcc agaatgggga
3301 cccatgcaac catgaaaatt caggggcgca cagttggagg gcaaatgggt atgctcctga
3361 caggatccaa cgccaagagt atggacctag gcacaacacc aggcgactgc ggctgcccct
3421 acatctacaa gagggggaat gactacgtag tcataggagt ccatacggcc gctgcccgtg
3481 gaggaaacac tgtcatatgt gccacccagg ggagtgaggg agaagccaca cttgaaggag
3541 gtgacagtaa aggaacatac tgtggcgctc caatcttggg cccagggagc gctccgaagc
3601 tcagcaccaa gactaagttt tggagatcat ccacaacacc actcccacct ggcacctacg
3661 aaccagccta cctcggtggc aaagacccca gagtcaaagg tggtccttca ttgcaacaag
3721 ttatgaggga ccagctaaag ccattcacag aacccagagg caaaccacca agaccaaatg
3781 tgttggaatc tgccaagaaa accatcatca atgtccttga gcaaacaatt gatccacccc
3841 aaaaatggtc atttgcgcaa gcttgcgcat cccttgacaa aaccacctcc agcggccacc
3901 cgcaccacat gcggaaaaac gattgttgga atggggagtc attcacagga aaattggctg
3961 atcaagcctc caaggccaac ctaatgtttg aggagggaaa gaacatgact ccagtctaca
4021 caggtgcact taaagatgag ttggtaaaga ccgataaagt ttatggtaag atcaaaaaga
4081 ggcttctgtg gggttcagat ctggcgacca tgatacggtg cgcccgggct tttggaggcc
4141 ttatggatga actcaaggcg cactgtgtca cactacctgt cagagttggt atgaacatga
4201 atgaggatgg ccccatcatc tttgagaagc actccagata tagatatcac tatgatgctg
4261 actattcccg gtgggactca acacaacaaa gggatgtgct agcagcagca ctagaaatca
4321 tggtcaagtt ctctccagag ccacacctgg cccaggtagt tgcagaagac ctcctttccc
4381 ctagcgtgat ggatgtaggt gactttcaaa tatcaataag tgagggtctt ccctctgggg
4441 taccttgcac ctcccagtgg aattccatcg cccactggct cctcacactt tgtgcactct
4501 ctgaagtcac ggacctgtcc cctgatatca ttcaggccaa ctcccttttc tccttctatg
4561 gtgatgatga gattgtgagc acagacataa agttggaccc agagaagctg acggcaaaac
4621 tcaaggagta cgggctgaaa ccaacccgcc ccgacaaaac tgaaggaccc cttgttatct
4681 ctgaagacct ggatggcctg acattcctcc ggagaactgt gacccgtgat ccagctggct
4741 ggtttggaaa attggaacaa agttcaattc tcagacaaat gtactggacc aggggtccca
4801 accatgaaga tccatttgaa acaatgatac cacactccca aagacccata cagttgatgt
4861 ccttgctggg cgaggctgca ctccacggcc cggcatttta tagcaaaatt agtaaattag
4921 tcattgcaga gttgaaagaa ggtggcatgg atttttacgt gcccagacaa gagccaatgt
4981 tcagatggat gagattctca gatctgagca cgtgggaggg cgatcgcaat ctggctccca
5041 gttttgtgaa tgaagatggc gtcgagtgac gccaacccat ctgatgggtc cgcagccaac
5101 ctcgtcccag aggtcaacaa tgaggttatg gctctggagc ccgttgttgg tgccgccatt
5161 gcggcacctg tagcgggcca acaaaatgta attgacccct ggattagaaa caattttgta
5221 caagcccctg gtggagagtt tacagtgtcc cctagaaacg ctccaggtga aatactatgg
5281 agcgcgccct tgggccctga tctaaatccc tacttatccc atttggccag aatgtacaat
5341 ggttatgcag gtggttttga agtgcaggta attctcgcgg ggaacgcgtt caccgccggg
5401 aaggtcatat ttgcagcagt cccaccaaat tttccaactg aaggcttgag ccccagccag
5461 gtcactatgt tcccccatat agtagtagat gttaggcaac tagaacctgt gttgatcccc
5521 ttacccgatg ttaggaataa tttctatcat tataatcaat caaatgaccc caccattaag
5581 ttgatagcaa tgttgtatac accacttagg gctaataatg ctggggatga tgtcttcaca
5641 gtttcttgcc gagttctcac gagaccatcc cccgattttg atttcatatt tctagtgcca
5701 cccacagttg agtcaagaac taaaccattc tctgtcccag ttttaactgt tgaggagatg
5761 accaattcaa gattccccat tcctttggaa aagctgttca cgggtcccag cagtgccttt
5821 gttgtccaac cacaaaacgg caggtgcacg attgatggcg tgctcctagg caccacccaa
5881 ctgtcccctg tcaacatctg caccttcaga ggagatgtca cccacgtcac aggtagtcat
5941 aactacacaa tgaatttggc ttctcaaaat tggaacaatt atgacccaac agaagaaatc
6001 ccagcccctc taggaacccc agactttgtg gggaagattc aaggcgtgct cacccaaacc
6061 acaaggacag atggctcaac acgcggccac aaagccacag tgtacactgg gagcgccgac
6121 tttgctccaa aactgggtag agttcaattt gaaactgaca cagaccgtga ttttgaagct
6181 aaccaaaaca caaagttcac cccagtcggt gtcatccaag atggtagcac cacccaccaa
6241 aatgaacccc aacagtgggt gctcccaagt tactcaggca gaaatactca taatgtgcat
6301 ctggcccccg ctgtagcccc cacttttccg ggtgagcaac ttctcttctt cagatccacc
6361 atgcccggat gcagcgggta ccccaacatg gttttggact gtctgctccc ccaggaatgg
6421 gtgcagttct tctaccaaga ggcagcccca gcacaatctg atgtggctct gctaagattt
6481 gtgaatccag acacaggtag ggttttgttt gagtgtaagc ttcataaatc aggctatgtt
6541 acagtggctc acactggcca acatgatttg gttattcccc ccaatggtta ttttagattt
6601 gattcctggg tcaaccagtt ctacacgctt gcccccatgg gaaatggaac ggggcgtaga
6661 cgtgcagtat aatggctgga gctttctttg ctggattggc atctgatgtc cttggctctg
6721 gacttggttc ccttatcaat gctggggctg gggccatcaa ccaaaaagtt gagtttgaaa
6781 ataacagaaa attgcaacaa gcatccttcc aatttagcag caatctacaa caggcttcct
6841 ttcaacatga caaagagatg ctccaagcac aaattgaggc caccaaaaag ttacaacagg
6901 aaatgatgaa agttaagcag gcaatgctcc tagagggtgg gttctctgag acggatgcag
6961 cccgcggggc aatcaacgcc cccatgacaa aagctttgga ctggagcggg acaaggtact
7021 gggctcccga tgctaggact acaacataca atgcaggccg cttttccacc cctcaaccat
7081 cgggggcaca gccaggaaga gctaatctta gggaagctgt ccctgctcgg ggttcctcca
7141 gtaaatcttc taactcttct actgctactt ctgtgtactc aaatcaaact acttcaacga
7201 gacttggttc tacagctggt tctggtacca gtgtctcgag cctcccgtca actgcgagga
7261 ctaggagctg ggttgaggat caaagtagga atttgtcacc tttcatgagg ggggcccaca
7321 acatatcgtt tgtcacccca ccatctagca gatcctctag ccaaggcaca gtctcaaccg
7381 tgcctaaaga gattttggac tcctggactg gcgctttcaa cacgcgcagg cagccactct
7441 tcgctcacat tcgtaagcga ggggagtcac gggtgtaatg tgaaaagaca aaattaatta
7501 tctttctttt tctttagtgt ctttt
//