Typing tool
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Typing tool
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Complete norovirus genomes
| MW305533 | GII.5 | |
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| GII.P40 |
ORF1: 1..5105
ORF2: 5086..6708
ORF3: 6708..7484
LOCUS MW305533 7519 bp RNA linear VRL 06-JUL-2021
DEFINITION Norovirus GII isolate ONVHH0987 nonstructural polyprotein (ORF1)
gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete
cds.
ACCESSION MW305533
VERSION MW305533.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7519)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses reveal coexistence of
viral populations evolving under recombination constraints
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7519)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7519
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="ONVHH0987"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Peru"
/collection_date="04-Oct-2013"
/note="genotype: GII.5[GII.P40]"
gene <1..5105
/gene="ORF1"
CDS <1..5105
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QPJ58935.1"
/translation="TAGNTSTNSVIHNQDVNSTSSLFANMTVGLKRALGARPKQPAPR
VPSPNREGRHETTPRAPPPNKGGNANIPPIPPPPPNGEDIVIKYTKQDDAVEGVPTVA
TVDVPPTHNTAYSVPPLDQREKIEAKEPLTGSILEMWDGEIYHYGLYVEKGLVLGVHK
PPAAISFARIELTPLSLYWRTVYTPPYLIAPETLRKLHGESFPYTAFDNNCYSFCCWV
LDLNDSWLNRKFVSRTTGFYRPYQEWNRKPLPTMDEGKLKKVANVLLCGLSGLFTRPI
KDLIGKLRPLNILNIITNCDWTFPGIVEAFILLAELFGVFWTPPDISTFIASLLGDYE
MQGPEDIAVEVVPVILGGIGMVLGFTKERIGRLLSSAASSLRACREIGNYGIEVVKLV
MKWFFPTKDETNEMDMVRAIEDAVLDFEAIQNNHMTALLKDKNSLATFLRELDMEEEK
ARKLSTKSASPDIIGTINALLARIAAARSLVHKAKEEMSSRMRPVVIMISGRPGIGKT
HLARDLAKKMAATLSGDQRVGLVPRNGVDHWDAYKGERIVLWDDYGMSNPVTDALRLQ
ELADTCPLTLNCDRIENKGKVFDSDTIIITTNLANPAPLDYVNFEACSRRIDFLVYAD
SPSVDKAKRDFPGQPDMWKDAFKPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKTLTTH
SLIARATGLLHERLDEFDLQGPELPVYNFDHNRVAAFRRLAADNRYGLMETIKVGNKL
KSVKTLEQLKDALKDISIMPCRIVYNSMAYDLDSNGSGRVSVKKVVDHKIQTNNELNS
ALNNLRGARVRYYVKCVQEMVYSLLQIAGAAFVTSRMTRRLNVSSIWARPEKQVEATE
EPPSPPTEDWTITPANAVQEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERQ
GKYSIEEYLQDRDRYYEELAIAKATEENFCEEEEIKIRQRVFRPTRKQRKEERATLGL
VTGSEIRKRNPDDFKPRGKLWADDDRSVNYNEKIDFEAPPSLWSRIVNFGSGWGFWVS
SNLLITSTHVIPPNMTEAFGVPISQIQVHRSGEFCKMRFPKAIRPDVSGMILEEGAPE
GTVVTILIKRTTGELMPLAARMGTHATMKIQGKMLGGQMGMLLTGSNAKNMDLGTIPG
DCGCPYVYKRGNDWVAIGVHTAAARGGNTVICATQGPDGEATLEGRDNHGTYCGAPIL
GPGSAPKLSTKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMREQLKPFTA
PRGKPPRPAILEAAKETICNVLEQIIDPPQKWSYAQACASLDKTTSSGHPHHMKKNDN
WNGESFTGVLADQASKANLMFEQGKHMQPVYTAALKDELVKTSKIYEKIKKRLLWGSD
LGTMIRCARAFGGLMDEMKANCVNLPIRVGMNMNEDGPIIFEKHSKYKYHYDADYSRW
DSTQQRHILGAALEIMVRFSAEPELAQIVSEDLLAPSVVDVGDFKITINEGLPSGVPC
TSQWNSISHWLITLCAISEISGLSPDVVQTNSCFSFYGDDEIVSTDIKLDPMKLTNKL
KEYGLIPTRPDKTEGPLIIKENLDGLTFLRRDVCRDPAGWYGKLDQSSIMRQLFWTKG
PNHDDPNETMIPHSQRPIQLMSLLGEAALHGPVFYKKVSKLVITELKEGGMDFYVPRQ
EPMFRWMRFSDLSTWEGDRNLAPEGVNEDGVE"
mat_peptide <1..1010
/gene="ORF1"
/product="p48"
mat_peptide 1011..2108
/gene="ORF1"
/product="NTPase"
mat_peptide 2109..2645
/gene="ORF1"
/product="p22"
mat_peptide 2646..3029
/gene="ORF1"
/product="VPg"
mat_peptide 3030..3572
/gene="ORF1"
/product="Pro"
mat_peptide 3573..5102
/gene="ORF1"
/product="RdRp"
gene 5086..6708
/gene="ORF2"
CDS 5086..6708
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ58936.1"
/translation="MKMASNDATPSNDGAAGLVPESNSEAMALEPVVGASLAAPVTGQ
TNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILVNLELGPELNPYLAHLARMYNGYAGG
MEVQVMLAGNAFTAGKIIFAAVPPYFPVENLSPSQITMFPHVIIDVRTLEPVLLPMPD
VRSTLFHFNQKDEPKMRLVAMLYTPLRSNGSGDDVFTVSCRILTRPSPEFDFTYLVPP
TVESKTKPFTLPVLTLGELSNSRFPLSIDEMVTSPNESIVVQPQNGRVTLDGELLGTT
QLQACNICSIRGKVTGQVPNEQHMWNLEITNLNGTQFDPTDDVPAPLGVPDFAGEVFG
VLSQRNRGESNPANRAHDAVVATYSDKYTPKLGLVQIGTWNTNDVENQPTKFTPIGLN
EVANGHRFEQWTLPRYSGALTLNMNLAPAVAPLFPGERLLFFRSYVPLKGGFGNPAID
CLVPQEWVQHFYQESAPSLGDVALVRYVNPDTGRVLFEAKLHKGGFLTVSSTSTGPVV
VPANGYFRFDSWVNQFYSLAPMGTGNGRRRFQ"
gene 6708..7484
/gene="ORF3"
CDS 6708..7484
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ58937.1"
/translation="MAGAFIAGLAGDVLSNGLGSLINAGANAINQRAEFDFNRQLQQN
SFNHDKEMLSAQIQATKQLQADMIAIKQGVLAAGGFSPTDAARGAVNAPMTQALDWSG
TRYWAPGSMKTTSYSGKFVSMNPVRQVEFPQPKKSAAIPSSASSVSSGRTNLTNSTQS
TVVSTSSVSPSRGSSAPSTLSRTTTRTSNWVEEQNRNLEPYMRGALQTTFVTPPSSRA
SSSGTVSTVPKGVLDSWTPAFNTRRQPLFAYLRKKGESQV"
ORIGIN
1 cgaccgctgg caataccagc acaaacagtg taattcacaa ccaagatgta aattctacat
61 ctagcctctt tgccaacatg actgttggcc tgaagagggc cctgggggcg agaccaaaac
121 aacccgctcc cagggttcct tcccccaaca gggagggaag acatgaaacc actcctagag
181 ctccccctcc gaacaaggga ggtaatgcta acatcccacc aataccaccc ccaccgccca
241 acggggagga catagtcatc aagtatacca agcaggatga cgcggttgaa ggggtgccca
301 ccgtcgccac ggttgatgtt ccccccacac acaacaccgc ttacagtgtc ccccccctgg
361 atcagaggga gaagattgaa gcgaaggagc ccttgacagg ttcgatactt gagatgtggg
421 acggtgagat ctaccactat ggtctctacg tggagaaggg cttggttctt ggtgtgcaca
481 aacctccagc tgccataagc tttgcacgca tagaactcac tcccctctcc ctatactgga
541 gaacagtcta cactccacct tacctgatag ccccagaaac cctaaggaag ctccacgggg
601 agtcattccc atatacagcc tttgacaaca attgctattc cttctgctgc tgggtcctgg
661 acctgaacga ttcttggctc aacagaaaat ttgtatcaag gacaacgggt ttctacagac
721 cctaccaaga gtggaataga aagcctttgc caaccatgga tgaaggaaag ctcaagaaag
781 tggccaatgt gcttctatgt ggtctctctg ggcttttcac taggcccatc aaggatctca
841 tagggaagtt gaggccacta aacatactaa acatcatcac caattgcgac tggactttcc
901 ccggaattgt ggaggctttc atactgcttg cagagctctt tggagttttc tggacaccac
961 cagacatttc caccttcata gcttcacttc tgggtgacta tgaaatgcag ggccctgagg
1021 atatcgcggt tgaagtcgta ccggtgatcc tcggcggcat aggtatggta cttggattca
1081 ccaaagaaag aattggccgg ttgttgagct ctgccgcttc ctcacttaga gcgtgcaggg
1141 agatcggcaa ctatgggata gaagtagtga agctggtgat gaaatggttt ttccccacca
1201 aagatgagac aaatgagatg gatatggtga gggcaataga ggatgctgtt cttgactttg
1261 aagccataca gaacaatcac atgacagcat tgcttaaaga caaaaacagc cttgcaacct
1321 tcctcaggga gctggatatg gaagaggaaa aggcgcggaa gctatcaaca aaatctgcgt
1381 ccccagatat tatcggcacc ataaacgccc ttctagccag aattgccgct gctaggtccc
1441 tagtccacaa ggccaaggaa gaaatgtcat ctaggatgcg tcctgttgtc atcatgatct
1501 ccggccgacc cgggataggg aagacgcatt tggcccgcga cctggctaag aagatggcgg
1561 cgaccctctc aggtgatcag agagtggggc tcgtgccgag gaatggtgtt gaccattggg
1621 acgcatataa aggagagagg atcgtgctct gggacgatta tgggatgagc aaccctgtga
1681 ctgatgcact gcggcttcag gagcttgccg acacatgccc cctaacgctt aactgtgata
1741 gaatagaaaa taagggaaaa gtgtttgaca gtgacactat aatcatcacc actaatttgg
1801 ccaatcctgc tcctctagat tatgtcaact ttgaagcttg ctcccgccga atcgacttcc
1861 ttgtctatgc agactccccc tcggtggaca aggcgaagag agacttccct ggtcaaccag
1921 acatgtggaa ggatgccttt aaaccggact tttcacacat aaaacttcag ttggcaccac
1981 agggaggctt tgataagaac gggaacaccc ctcatggaaa aggtgtcatg aaaacgctaa
2041 ccacacactc actcattgcc cgcgccacgg gcctcctaca tgagagattg gatgaatttg
2101 acctgcaggg acccgagttg cccgtgtaca attttgacca caacagggtg gctgctttca
2161 ggagactggc agctgacaac aggtatgggc ttatggaaac cataaaggtg ggtaacaaat
2221 tgaaaagcgt caagactcta gaacaactca aggacgctct aaaagacata agtatcatgc
2281 cttgcagaat agtctacaac tcgatggctt acgatctcga ttcgaacgga tcagggagag
2341 tcagtgtcaa aaaggttgta gaccacaaga tccagaccaa caacgagctc aattccgccc
2401 tcaacaatct gcgcggtgcc agagtgagat actatgttaa atgtgttcaa gagatggtat
2461 attccctcct tcaaattgct ggcgcagcct tcgtcacctc aagaatgaca cggaggttga
2521 acgtcagcag catttgggcc agaccagaaa aacaagtgga ggccactgag gaacccccat
2581 cccccccaac tgaggactgg actataaccc cagcaaatgc agtccaggaa ggtaaaaagg
2641 gcaagaacaa gagcggcaga ggcaagaaac ataccgcctt ctccagtaaa ggcctaagtg
2701 atgaggagta tgatgagtat aaaagaatca gagaagagag acaaggaaaa tactccatag
2761 aagaatacct tcaggatagg gaccggtatt atgaggaatt ggccatagcc aaggcaacag
2821 aggagaactt ctgtgaggag gaagaaataa aaatcagaca gagggtcttc cgtccgacca
2881 ggaaacaacg caaggaagag agggcaactc taggactggt cacaggtagt gaaataagga
2941 agaggaaccc agatgatttc aagccaagag gaaaattgtg ggctgatgat gaccgcagtg
3001 taaattacaa tgagaaaata gattttgagg cgcctcccag cctttggtct cgaatagtca
3061 acttcgggtc aggttggggt ttttgggtct cttccaactt gctcatcaca tcaacacatg
3121 tcatcccccc gaacatgact gaggcctttg gtgtaccaat aagtcagata caagtacata
3181 ggagtggaga gttctgtaaa atgaggttcc ccaaagctat aagacctgat gtctcaggca
3241 tgatccttga ggaaggagct cccgagggaa cggtggtgac catactgatc aagaggacca
3301 ccggtgagct catgccactg gccgcccgaa tgggtaccca cgccaccatg aaaattcaag
3361 ggaaaatgct tggaggccaa atgggcatgc tcctcacggg gtccaacgcc aagaacatgg
3421 acctcggtac cattcctgga gactgtggtt gtccctatgt ctacaagaga ggtaatgact
3481 gggtggctat aggggtgcac accgcagccg ccagaggtgg caacaccgtg atttgtgcca
3541 cccagggtcc agacggtgag gccacgcttg aggggagaga caaccacggg acttactgtg
3601 gggcaccaat acttggacca ggaagtgcac caaaactcag cactaagact aaattctgga
3661 ggtcatccaa cgccccactc ccgcctggca cttatgagcc cgcttaccta ggcggaaaag
3721 acccaagagt caagggggga ccatcactac agcaagtcat gagggaacaa ctcaaacctt
3781 tcacagcccc ccgagggaag cccccacgac cggcgatcct ggaggctgct aaggaaacca
3841 tctgtaatgt acttgagcag atcattgacc caccccaaaa atggtcttat gctcaggcct
3901 gtgcctctct ggacaaaaca acatccagtg gccatcccca ccatatgaaa aagaatgaca
3961 actggaacgg agagtccttc accggtgtgt tggctgacca agcttccaag gcaaatctca
4021 tgtttgaaca agggaaacac atgcaacctg tgtacaccgc cgccctcaaa gacgagctcg
4081 tcaagactag caagatctat gagaaaatta agaagaggct cctatggggt tcagatctgg
4141 gcacaatgat ccgctgtgct agggcttttg gaggcctcat ggatgagatg aaagcaaatt
4201 gtgtaaactt accaatcaga gttggcatga acatgaatga agatggaccc atcattttcg
4261 agaaacattc aaagtataag taccattatg atgctgacta ttctaggtgg gattcaaccc
4321 aacagagaca tatcttgggg gctgcccttg agataatggt taggttctca gctgaacctg
4381 aattggccca aattgtatct gaagatctcc tagcccccag cgtggtggac gttggcgact
4441 tcaagatcac cataaatgaa ggtttgccct ctggagtgcc gtgcacatca caatggaact
4501 caatttccca ctggctaata acactatgtg ccatatcaga aatttcaggg ctgtcgccag
4561 atgtggtaca aacaaactcc tgtttctcct tctatgggga tgatgagata gtcagcactg
4621 acattaagtt ggatcccatg aaattaacta acaagttgaa ggagtatgga ctgatcccaa
4681 caagaccaga caagacagag gggccactca taatcaaaga gaaccttgat ggcttaacct
4741 ttctgaggag ggatgtgtgt cgggacccag ctggttggta tggaaaactt gatcaatcct
4801 caattatgag acaattgttt tggaccaagg ggcccaacca tgacgatccc aatgagacaa
4861 tgattccaca ctcccagagg cccatacaac taatgtcatt gctgggggag gcagcattac
4921 acggaccagt tttctacaag aaagtcagta aattagttat cactgagctc aaagagggtg
4981 gaatggattt ttacgtgcca aggcaagaac ctatgtttag gtggatgaga ttctctgacc
5041 tcagcacttg ggagggcgat cgcaatcttg ctcccgaagg tgtgaatgaa gatggcgtcg
5101 aatgacgcta ctccatcaaa tgatggcgct gccggcctcg tgccagaaag taacagtgag
5161 gcaatggctc tggaacccgt ggtgggggcg tctttagccg cccctgtcac tggccaaact
5221 aatataatag acccctggat cagaactaat tttgtccaag cccctaatgg tgaattcaca
5281 gtttctccta gaaattcccc tggagagata ttggtcaatt tggagttagg tccagaactg
5341 aacccttatc tggcacattt agctaggatg tacaatggtt atgcgggtgg tatggaggtg
5401 caagtgatgc tcgcggggaa cgcgttcact gctggcaaga tcatctttgc cgccgtgcca
5461 ccttactttc cagtggaaaa tcttagccct tcccaaataa caatgttccc acatgtgatt
5521 atcgatgtta gaaccttaga acctgtactg ctcccaatgc ctgatgtcag aagcaccctt
5581 ttccacttta atcaaaagga tgaacctaag atgagacttg ttgccatgct ctacacccct
5641 cttcgttcta atggctctgg tgatgatgtt ttcactgtct catgtaggat cctcactagg
5701 ccctctcctg aatttgattt cacatacttg gtgccaccaa cagtagagtc aaagaccaag
5761 ccattcacac tacctgtgct gacattggga gaattgtcca attctagatt ccctctctct
5821 attgatgaaa tggtcaccag ccctaatgag tccatagttg ttcagccaca gaatggtagg
5881 gtcacactag atggggagtt gttaggcaca acccaactac aagcatgtaa catttgttcc
5941 ataaggggga aagtgacagg acaggtccct aatgaacaac acatgtggaa cctggagatt
6001 acaaacctaa atgggacgca atttgaccct acagatgatg tcccagcccc tcttggtgtg
6061 cccgactttg caggtgaggt ctttggtgta ctcagccaga gaaatagagg tgaaagcaat
6121 ccagcaaaca gggctcatga tgctgttgtg gctacctaca gtgataaata cacccctaaa
6181 ttgggcttag tgcaaattgg gacttggaac accaacgatg ttgaaaacca gccaacaaaa
6241 ttcaccccaa ttggtttgaa tgaggtcgcc aatggccatc gatttgaaca gtggaccttg
6301 cctaggtatt ctggtgccct gacactaaat atgaatttag ctcctgctgt ggccccgctc
6361 ttccctggag agcgtctcct tttcttccgc tcttacgtcc cattaaaagg tggatttgga
6421 aaccctgcta tagattgtct agtgcctcag gagtgggtcc aacatttcta ccaggaatct
6481 gccccatctc tgggggatgt ggccttagtc aggtacgtca acccagacac cgggcgcgtc
6541 ctttttgagg ccaaactcca caaaggtggg ttcctgaccg tgtcaagcac tagcacaggg
6601 cctgttgtgg tcccagccaa tggttatttc agatttgatt cttgggtcaa tcaattttac
6661 tctcttgccc ccatgggaac tgggaatggg cgtagaaggt ttcagtaatg gcaggagctt
6721 tcatagcagg tttagcaggt gatgtgctta gtaatggcct cggttcgctg attaatgccg
6781 gagccaatgc tatcaatcaa agagcagaat ttgattttaa taggcaattg cagcaaaatt
6841 cttttaatca tgataaggag atgttaagtg cccaaattca agcaacaaaa cagttgcagg
6901 ctgacatgat agcaatcaaa cagggagtcc tagctgctgg gggtttctca ccaactgatg
6961 cagccagagg agctgtcaat gcacccatga cccaagcatt agattggagt ggcactaggt
7021 attgggcccc tggttcaatg aagaccacca gctattctgg aaagtttgtg tccatgaacc
7081 ctgttaggca ggttgagttc ccgcagccca aaaagagtgc ggccatacca tcaagtgcca
7141 gctctgtgtc ttctggtagg actaatctca caaattctac tcaatcaact gttgttagca
7201 cttcctcagt atcaccttct agaggttctt ctgctccttc tactctatca aggactacaa
7261 ccagaacttc caattgggtt gaggaacaaa acaggaattt ggaaccctac atgaggggtg
7321 ccctccaaac aacatttgtc accccccctt ccagccgggc atctagcagc ggtacagtct
7381 caactgtacc aaaaggtgtt ttggactcct ggacacctgc gtttaacacc cgcaggcaac
7441 cgcttttcgc ttaccttcgc aagaaggggg agtcacaagt ttagtgaaaa gataattagt
7501 gattgataat tgatctttt
//