Typing tool
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Typing tool
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Complete norovirus genomes
| MW305532 | GII.6 | |
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| GII.P7 |
ORF1: 1..5063
ORF2: 5044..6696
ORF3: 6696..7475
LOCUS MW305532 7528 bp RNA linear VRL 06-JUL-2021
DEFINITION Norovirus GII isolate ONVHH0813 nonstructural polyprotein (ORF1)
gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete
cds.
ACCESSION MW305532
VERSION MW305532.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7528)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses reveal coexistence of
viral populations evolving under recombination constraints
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7528)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7528
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="ONVHH0813"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Peru"
/collection_date="18-Sep-2013"
/note="genotype: GII.6[GII.P7]"
gene <1..5063
/gene="ORF1"
CDS <1..5063
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QPJ58932.1"
/translation="LGSQNSVNDSINTTPSNKEEAGAFSNIKVGFKKMLGAVPKGTKA
PSSDQHCPTVKIGPKTLTVPPEPPNGEDTIQFDAKSETVIGLPDLTTVQNEHENTPYT
VPPLSEREHRPATEPLPGTILEMWDGEFYHYSVYVSGGKALGVHKPPAAISLATIELT
PISLYWRPVYTPNYLVCPDTLKGLAGEKFPYTAFSNNCYNFCCWVLELNDTWFSRRSI
SRTTGFFKPYQSWNRKPLPTVDDGKIKKVANAILCALGSLFSKPIKDLLGKLKPLNLL
HLLASCDWTFAGIVETVILMAELFNVFWTPPDVSNFIASLIGDFELQGPEDLAVELVP
VVMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMKWFFPKKEEKAE
METLRAIEDAVLDMEAIGNNHLTTLLKDKDSLTAFMKTLDLEEEKARKLSTKSSSPDI
VGTINAILARIAAARSLLHKAKEEMFSRIRPVVVMISGRPGIGKTHMARHLAKNIANT
MSGDQRVGLVPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALTLQELADTCPVTLNCD
RIENKGKMFDSDVIIITTNLVNPAPLDYVNFEACSRRIDFLVYAESPEIEKVKRDFPG
QPDMWKDYFKQDFSHIKLTLAPQGGFDKNGNTPHGKGTMRSLTQGSLTARVAGLVHER
KDEFQLQGNDLQTYNFDTNRVSAFRKLAADNKYGIMETMRVGAALKNVKTLEDLKVAL
RDVKFNECEIIYRNSKYRVSSNGKGSVSVDKVEDHTSQTANEVGSALLRLRQARARYY
VSCFQDLVYTLIQVAGASFVVNRISKRFCWERWVKPTETQEASEPEKEVAQGGWEIEP
KDTEPEGKKGKNKKGRGKKHTAFSSKGLSDEEYDEFKRIREERNGKYSIEEYLQDRDR
YYEEVAVARATEEDFCEEEEAKIRQRIFRPTRKQRKEERGVLGLVTGSDIRKRKPDDF
QPKGNLWADDTRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSNLLITTTHVLPKG
IKELFGVEVKQIQIHKSGEFCRFRFPRPIRPDVTGLVLEEGAPEGTVCSILVKRPTGE
MIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDCGCPYIYKRGNDI
VVAGVHTAAARGGNTVICATQGQDGEAVLEGNENLGTYCGAPILGPGKAPKLSTKTKF
WRSSPDALPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEPRGKPPRPAVLEEA
KKTVMNVLEQTIDPAKPWTYSQACASLDKTTSSGSPHHVRKNDHWNGESFTGPLADQA
SKANLMYEQAKHVQPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGTMIRCARAFGGL
MDSMKASCIALPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDSTQQRNILSAAME
VMVRFSAEPELAQVVAEDLLAPSQLDVGDFVISVQEGLPSGVPCTSQWNSIAHWILTL
SAMAEVSGLSPDVVQAHSCFSFYGDDEIVSTDINLDPMKLTQKLREYGLVPTRPDKTE
GPLVITEDLTGLTFLRRSIARDPAGWFGKLDQDSILRQLYWTRGPNHENPYESMVPHS
QRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEAMFRWMRFSDLST
WEGDRNLAPEGVNEDGVE"
mat_peptide <1..971
/gene="ORF1"
/product="p48"
mat_peptide 972..2069
/gene="ORF1"
/product="NTPase"
mat_peptide 2070..2588
/gene="ORF1"
/product="p22"
mat_peptide 2589..2987
/gene="ORF1"
/product="VPg"
mat_peptide 2988..3530
/gene="ORF1"
/product="Pro"
mat_peptide 3531..5060
/gene="ORF1"
/product="RdRp"
gene 5044..6696
/gene="ORF2"
CDS 5044..6696
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ58933.1"
/translation="MKMASNDAAPSNDGAANLVPEANNEVMALEPVVGASIAAPVVGQ
QNIIDPWIRENFVQAPQGEFTVSPRNSPGEMLLNLELGPELNPYLSHLSRMYNGYAGG
MQVQVVLAGNAFTAGKIIFAAVPPHFPVDNISAAQITMCPHVIVDVRQLEPVLLPLPD
IRNRFFHYNQENTPRMRLVAMLYTPLRANSGEDVFTVSCRVLTRPAPDFEFTFLVPPT
VESKTKPFTLPILTLGELSNSRFPAAIDMLYTDPNESIVVQPQNGRCTLDGTLQGTTQ
LVPTQICAFRGTLISQTARAADSTDSPQRARDHPLHVQVKNLDGTQYDPTDDIPAVLG
AIDFKGTVFGVASQRDVSGTQEQGHYATRAHEAHIDTTDPKYAPKLGTILIKSESTDF
TTNQPIRFTPVGMGDNNWRQWELPDYSGRLTLNMNLAPAVSPSFPGERILFFRSIVPS
AGGFGSGYIDCLIPQEWVQHFYQEAAPSQSAVALVRYVNPDTGRNIFEAKLHREGFLT
VANPGNNPIVVPPNGYFRFEAWVNQFYTLAPMGSGQGRRRAQ"
gene 6696..7475
/gene="ORF3"
CDS 6696..7475
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ58934.1"
/translation="MAGAFFAGLAGDVVSNGIGSLINAGANAVNQKVEYDFNKQLQMA
SFKHDKEMLQSQVLATKQLQQEMMNIKQGMLTAGGFSPADAARGAVNAPMTKILDWNG
TRYWAPNSMKTTSYSGQFSSSPVHRSPAPLQHTAPPKSKLQSDSASVYSSPSTVSSQS
THSTVLSVGAGSSRSTPTSTATPTLSRTSDWVRGQNERLSPFMDGALQTTFVTPPSSK
ASSNGTVSTVPKAVLDSWTPMFNTHRQPLFAHLRRRGESQI"
ORIGIN
1 cccttggcag tcaaaactct gtcaatgaca gtatcaacac caccccttca aacaaagaag
61 aggctggtgc attctccaat atcaaagttg gatttaagaa aatgctgggt gccgtaccta
121 agggcactaa agcacccagc agtgaccagc actgtccaac agttaagatc gggcccaaaa
181 cactaacagt tccccctgaa cccccaaatg gtgaagacac tatacagttt gatgcaaaat
241 cggaaacagt aattgggcta ccggacttga caacagtgca aaatgaacat gaaaacaccc
301 catacactgt ccctccactg agtgagaggg aacacagacc agccactgag ccgcttcctg
361 gcacaatact ggagatgtgg gatggtgaat tctaccacta ctctgtgtac gtcagcggtg
421 gcaaagctct gggggttcac aaacctccgg cagctataag tctcgcgacg atagagctca
481 cccccatatc tctatactgg aggcctgttt acacccccaa ctacctggtc tgcccagaca
541 cactgaaagg tctcgctggt gaaaagttcc cttacacggc cttcagcaac aattgctaca
601 acttctgctg ctgggtgctt gaactcaatg atacgtggtt tagcagaaga agcatttcca
661 gaaccaccgg cttcttcaaa ccgtaccagt cttggaacag gaaacctctc ccaaccgttg
721 atgatggaaa gatcaaaaag gtggccaacg cgatcctttg tgcactcggt tcgctgttct
781 caaaaccaat caaggatctg ctaggcaagc tcaaaccatt gaacttacta catctgctcg
841 cgtcgtgtga ttggacgttt gcaggtatag tggagacagt cattttaatg gcagaactct
901 tcaacgtctt ttggaccccg ccagacgtct ccaattttat agcctccctc ataggtgatt
961 ttgaattgca ggggcctgag gacttggcgg tagagcttgt tcctgtggtc atgggtggta
1021 taggaatggt tctcggtttc acagctgaga agataggtcg catgctgtca tccgctgcat
1081 caacactgcg ggcgtgtaaa gacttaggga actatgccct tgacatactt aaattggtca
1141 tgaaatggtt cttcccaaag aaagaggaga aagccgagat ggaaaccttg agggcgattg
1201 aggatgccgt cctagatatg gaggccatag gtaacaacca cctcacaacc ctcctcaagg
1261 ataaagacag tctcacggcc ttcatgaaga ccttggattt ggaagaagag aaagcaagga
1321 agctatccac caagtcatcc tcgccggaca tcgtcggcac tatcaatgcc atactggcta
1381 ggatagctgc cgctagatcc cttctgcaca aagccaaaga agagatgttc agcaggatca
1441 gaccagtggt tgttatgatc tcaggcagac ctggcattgg caaaacccat atggcgagac
1501 atttggctaa gaacatcgcc aacaccatga gtggtgacca aagagtcggg ctcgtcccgc
1561 gcaacggggt cgaccactgg gacgcttaca ggggagagag ggtggtcttg tgggatgatt
1621 acggaatggg gaaccctgtc aaagatgctc taacactgca agagctagct gatacatgcc
1681 cagtcactct aaactgtgac aggattgaga acaagggaaa aatgttcgac agtgatgtca
1741 tcataatcac gaccaaccta gtcaaccctg cacctctcga ttatgtgaac ttcgaggcgt
1801 gctctagaag aattgatttc ttggtctatg cagagtcacc agaaattgag aaggttaaga
1861 gagatttccc tggccaacct gacatgtgga aagactattt caaacaagac ttttcccata
1921 taaagctaac cctagccccc caaggcggat ttgacaagaa tggtaacacc ccgcatggta
1981 agggtaccat gcgatccctc acccaggggt ccctgaccgc aagggtagca ggacttgtcc
2041 atgagaggaa ggatgagttc cagctacaag ggaatgacct ccagacatac aactttgaca
2101 ccaacagggt ctctgcgttc aggaaactgg ctgcagacaa caagtatgga attatggaaa
2161 caatgagagt gggtgcagcg ctcaaaaatg tcaaaacttt ggaagatctg aaagtcgcct
2221 tgagagatgt gaagttcaat gagtgtgaaa taatttacag gaactctaag taccgggtct
2281 cttctaacgg caagggctct gtttctgttg ataaagttga ggaccacacg tctcagaccg
2341 caaatgaagt gggctcagca ctcctcagac ttaggcaagc aagggctaga tattatgtca
2401 gctgtttcca agacctcgtc tacactctca tacaggttgc tggggcgtca ttcgttgtca
2461 acaggatctc caaaaggttc tgttgggaaa ggtgggttaa accaactgaa acccaagaag
2521 cgagtgaacc cgaaaaggaa gtagctcaag gtggatggga gatagaaccc aaggacacag
2581 aaccagaagg caagaagggt aagaacaaga aagggagagg caagaaacac accgccttct
2641 ctagcaaagg cttaagtgat gaagagtatg atgagttcaa gagaatcagg gaagagagga
2701 atggaaaata ctccattgag gaatacctgc aagaccggga ccgctactat gaagaagtgg
2761 cggtcgcccg agcaacagaa gaggactttt gtgaagaaga ggaagccaag ataagacaaa
2821 gaatcttccg cccaacaagg aagcaaagaa aggaggaaag gggggtgctt ggcttagtca
2881 ctggctcaga tatcagaaag aggaaaccag acgattttca gccaaaaggc aatctgtggg
2941 cagatgacac taggagtgtg gactacaatg agagacttga ctttgaggct ccaccaagcg
3001 tctggtcaag aatagttcca ttgggcactg gttggggctt ctgggtttca tcaaacctcc
3061 tgatcacaac aacacacgtc ctgcccaagg ggatcaagga actctttggg gtcgaagtca
3121 aacaaattca aatccacaag tctggagagt tctgcaggtt caggttccca agaccaatca
3181 ggccagatgt cacaggactc gtgttggagg aaggcgctcc tgagggcact gtctgttcta
3241 tactcgttaa gaggcctaca ggtgagatga tccccctagc agtgaggatg ggcacgcacg
3301 catccatgaa aatacagggt aggaccgtcg gtggccagat ggggatgctt cttacagggg
3361 caaatgcaaa gaacatggac cttggcaccg gtcctggtga ctgcggttgt ccttacatct
3421 acaagcgtgg caacgacata gttgtcgcgg gtgtccacac cgcagcagcc cgggggggca
3481 acactgttat ttgtgccact caaggacaag acggagaggc agtccttgag ggaaatgaaa
3541 accttggcac ctactgtggt gctccaattc tgggccctgg caaagcgcct aaactcagca
3601 cgaaaaccaa attttggcgc tcatcaccag atgccctacc tcctggcacg tatgaacctg
3661 cttatctggg gggtaaggat cccagggtgg aaaaggggcc ctccctgcag caagttatga
3721 gagaccagct aaaaccattc acagagccca ggggcaaacc gcctagacca gcagttttag
3781 aagaggctaa aaagacagtg atgaatgttc tagaacagac cattgaccct gctaaaccat
3841 ggacttactc acaagcatgt gcttcactgg acaagaccac ttctagtgga agcccccacc
3901 atgtcaggaa aaatgaccac tggaatgggg agtcttttac tggtcccctc gcggaccaag
3961 catccaaagc caacctcatg tatgaacagg caaaacatgt gcagcccgtg tacacggccg
4021 cgctcaaaga tgagcttgtt aagactgata agatctacaa gaaaataaag aagagacttc
4081 tgtgggggtc agaccttggt acgatgatca ggtgtgccag ggcttttggc ggccttatgg
4141 acagtatgaa agcaagttgt atagcccttc catgcagggt ggggatgaac atgaatgagg
4201 atggccctat catatttgac aaacactcca agtataggta ccattatgat gctgactact
4261 ccaggtggga ctcaacccag caaaggaaca ttctttccgc cgccatggag gtgatggtga
4321 ggttctctgc tgaaccagaa ttggcacaag tggtcgcaga ggaccttttg gcgcctagcc
4381 agctagatgt tggcgatttt gtcatctcag tccaggaggg cctgccttca ggagtcccat
4441 gtacgtcaca atggaattca atagcgcact ggattctaac tctgagcgca atggcagaag
4501 tgtcaggtct ctcaccagac gttgtccaag cccactcctg tttttcattt tatggcgacg
4561 atgagatcgt cagcactgac atcaaccttg accccatgaa attgacacag aagctcagag
4621 agtatggtct ggtccctacc cggcctgata agactgaagg tcccctcgtt ataactgaag
4681 acctaaccgg cctgacattc ctgcgtagat caattgcacg ggatccagct ggatggtttg
4741 gaaaattgga tcaagactca atcctcaggc agttatactg gacaaggggg cccaatcatg
4801 aaaacccata cgagagcatg gttccccact cccagcgagc tactcagctc atggcccttc
4861 ttggtgaggc ttcattgcat ggtccccagt tttacaagaa agttagcaag atggtcatca
4921 atgagattaa gagtggtggt ctggagtttt atgtgcccag acaagaggcc atgtttaggt
4981 ggatgagatt ctctgacctc agcacatggg agggcgatcg caatcttgct cccgagggtg
5041 tgaatgaaga tggcgtcgaa tgacgccgcc ccatcaaatg atggtgctgc caacctcgta
5101 ccagaggcca acaatgaggt tatggcactt gaaccggtgg tgggagcttc aatcgcagct
5161 cctgttgtcg gtcaacagaa tataattgac ccctggatta gagaaaattt tgttcaagca
5221 ccacagggcg agtttactgt ttcaccaagg aattcgcccg gtgagatgct tttaaatctt
5281 gaattgggcc cagaacttaa cccctatttg agtcatttgt cccgcatgta caatgggtat
5341 gctggtggca tgcaggttca ggtggtccta gctgggaatg cgttcacagc tgggaagatc
5401 atctttgccg ctgtgccacc acacttccct gtggataata ttagtgcagc ccagataact
5461 atgtgtcccc atgtgattgt tgatgtgaga cagcttgaac cagtgcttct acccctcccc
5521 gatataagga ataggttctt ccattacaac caggaaaaca ccccccggat gagactcgtg
5581 gccatgctct acacgcctct aagggctaat tccggagagg acgtgttcac tgtgtcctgt
5641 agagttctga ctcgtcccgc tccagatttt gaattcacat ttttagttcc accaactgtt
5701 gaatcaaaaa caaaaccctt tactctacct attttaaccc ttggtgagtt gtccaattcc
5761 cgcttccctg ctgccataga tatgctttat actgatccca acgaatcaat agttgttcag
5821 ccccaaaatg gtagatgcac ccttgacggt acgttgcaag gcacaacaca attggtccca
5881 acacagattt gtgcctttag aggcaccctg atcagtcaga ctgcgagagc ggctgattca
5941 acagattccc cccagagagc ccgtgatcac ccgttgcacg tccaggtcaa gaacctagat
6001 ggtacacagt atgacccaac agatgacatc cctgcagtcc tgggggctat tgatttcaaa
6061 ggtacagtgt tcggagtggc gagccagagg gacgtctctg gaacacaaga acagggccat
6121 tatgccaccc gggctcatga agcacacatt gacacaactg acccaaagta tgcacctaaa
6181 ttaggtacaa ttctcattaa atctgaatct actgatttca ccacaaatca gcccattagg
6241 ttcactccag tgggtatggg tgacaataat tggagacagt gggaattgcc tgactactct
6301 ggtagattga ctttaaatat gaaccttgcc cctgctgttt ccccatcctt ccctggtgaa
6361 cgaatccttt tctttaggtc tatagtgcca tcagctggag gcttcgggtc tggctatata
6421 gactgtctta taccccagga atgggtgcaa catttctacc aggaggcagc accttcacaa
6481 tctgctgttg cactggttag gtatgtcaac cccgacactg ggcgtaacat ctttgaggcc
6541 aagttgcaca gagagggatt cctcaccgtg gctaatcctg gaaacaatcc tattgtggtt
6601 ccccctaatg gttattttag atttgaggct tgggttaacc aattctacac acttgccccc
6661 atgggatctg gacaggggcg tagaagagct cagtaatggc tggagccttc ttcgcagggt
6721 tagcaggtga tgtcgtgtcg aacggcatcg gttccctcat caatgcaggt gctaatgcag
6781 tcaatcaaaa ggttgagtat gattttaata agcaacttca gatggcatca ttcaaacatg
6841 ataaggagat gttacaatca caggtgttgg caaccaaaca actgcagcag gaaatgatga
6901 acataaagca ggggatgttg actgctggcg gcttctcccc tgctgacgct gctagagggg
6961 ctgttaacgc tccaatgaca aaaatactgg actggaatgg cacaagatat tgggcaccta
7021 atagcatgaa aaccacaagc tattcaggac aattctctag cagccccgtc cataggtctc
7081 ctgctcccct ccagcacacc gccccaccaa aaagtaagtt gcaaagtgat tctgctagtg
7141 tgtatagctc tccttccact gtttcttcac aatcaactca ctcaacagtg ttgtctgtag
7201 gagctgggtc gtccagatcc acccccacgt ccacagcaac ccccaccctg tctaggacca
7261 gcgactgggt tagaggacag aatgaaaggc ttagcccgtt tatggatggt gctctccaaa
7321 ccacttttgt cacaccacca tcgagcaaag cttcatcaaa tgggacagtc tcgaccgtgc
7381 ccaaagctgt tttggactcc tggactccta tgttcaacac acataggcag cctctcttcg
7441 cccatttgcg taggcgaggg gagtcacaaa tttagtgaaa agagtgatta ggttttcttt
7501 tccttcttcc tccccttttc tctctttt
//