Typing tool
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Typing tool
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Complete norovirus genomes
| MW305517 | GII.17 | |
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| GII.P13 |
ORF1: 1..5078
ORF2: 5059..6684
ORF3: 6684..7463
LOCUS MW305517 7487 bp RNA linear VRL 18-JUL-2024
DEFINITION Norovirus GII isolate PNV008216 nonstructural polyprotein (ORF1)
gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete
cds.
ACCESSION MW305517
VERSION MW305517.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norovirus norwalkense.
REFERENCE 1 (bases 1 to 7487)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A.U.A., Ford-Siltz,L.A., Green,K.Y.,
Galeano,M.E., Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N.,
Ushijima,H. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses provide insights on
evolutionary dynamics and evidence of coexisting viral populations
evolving under recombination constraints
JOURNAL PLoS Pathog 17 (7), e1009744 (2021)
PUBMED 34255807
REFERENCE 2 (bases 1 to 7487)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7487
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="PNV008216"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/geo_loc_name="Peru"
/collection_date="07-Jul-2008"
/note="genotype: GII.17[GII.P13]"
gene <1..5078
/gene="ORF1"
CDS <1..5078
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QPJ58887.1"
/translation="VAGKNNNNDNAKSSSDGLFSNMSVTFKKALGARPKQPPPGETKQ
ISKPPRPPTPELVKRIPPPPPNGEDEPKVVYKVGEGVSGLPDLTTVTQPDARCTAYSV
PPLSQREAGDAKEPLPGSILEMWDGEIYHYGLYVERGHVLGVHKPPAAISFAKIELTP
LSLYWRVVYTPQYLIAPDTLKDLNGESFPYTAFDNNCYAFCCWVLDLNDSWLSRRMIQ
RTTGFFRPYQEWNKKPLPTMDEPKIKKVANAVLCALSSLFTRPIKDIIGKLKPMNILN
ILATCDWTFAGIVESLILLAELFGVFWTPPDVSAMIAPLLGDFEMQGPEDLAVELVPV
VMGGIGLVLGFTKEKIGKMLSSAASTLRACKDLGAYGLEILKLVMKWFFPKKEEANEL
AMVRAIEDAVLDLEAIENNHMTTLLKDKDSLATYMRTLDLEEEKARKLSTKSASPDIV
GTINSLLARIAAARSLVHKAKEELSSRQRPVVVMISGRPGIGKTHLARELAKKVASTL
AGDQRIGLVPRNGVDHWDAYKGERVVLWDDYGMSNPIQDALRLQELADTCPLTLNCDR
IENKGKVFDSDAIIITTNLSNPAPLDYVNFEACSRRIDFLVYADAPDIEKAKRDFPGQ
PDMWKDHYRPDFSHIKLQLAPQGGFDKNGNTPHGKGVMKSLTVGSLIARASGLLHERM
DEFELQGPGLSTFNFDRNKVAAFRQLAAENKYGMLDTLRVGNQLKGVKTMDELKRAIN
NITIKKCLIVYNGCTYTMESDGRGKVLVDKVQNTTVQTNNELAGALHHLRSARIRYYV
KCFQEAIYSLLQIAGAAFVTSRIVRRMNISNLWSKPPAEDNDESEDKGGCPKPRDEDE
FTVDSKDIKVEGKKGKNKSGRGKKHTAFSSKGLSDEEYDEYKRIREERNGKYSIEEYL
QDRDRYYEELAIAKATEEDFCEEEEAKIRQRIFRPTRKQRKEERATLGLVTGSEIRKR
NPDDFKPRGKLWADDDRSVDYNEKISFEAPPSIWSRIVNFGSGWGFWVSSSLFITSTH
VIPKGITEAFGVPINQIQIHKSGEFCRLRFPKPIRTDVSGMILEEGAPEGTVATILVK
RPTGELMPLAARMGTHATMKIQGRMVGGQMGMLLTGSNAKSMDLGTTPGDCGCPYIYK
RGNDFVVIGVHTAAARGGNTVICATQGSEGEATLEGGDNKGTYCGAPILGPGNAPKLS
TKTKFWRSSNAPLPPGTYEPAYLGGKDPRVKGGPSLQQVMRDQLKPFTEPRGKPPNPS
ILESAKRTIINVLEQTIDPPQKWTYAQACASLDKTTSSGYPHHVRKNDYWSGETFTGK
LADQASKANLMYEEGKHMTPVYTAALKDELVKTDKIYGKIKKRLLWGSDLSTMIRCAR
AFGGLMEELKAHCITLPVRVGMNMNEDGPIIFEKHSRYNYHYDADYSRWDSTQQRAVL
ASALEIMVRFSAEPQLAQIVAEDLLSPSVVDVGDFKITINEGLPSGVPCTSQWNSISH
WLLTLCALSEVTGLGPDIIQANSMYSFYGDDEIVSTDIKLDPEKLTAKLKEYGLKPTR
PDKTEGPLVISEDLNGLTFLRRTVTRDPAGWFGKLDQSSILRQLYWTKGPNHEDPSET
MIPHAQRPVQLMALLGESSLHGPSFYSKVSKLVISELKEGGMDFYVPRQESMFRWMRF
SDLSTWEGDRNLAPSFVNEDGVE"
mat_peptide <1..968
/gene="ORF1"
/product="p48"
mat_peptide 969..2066
/gene="ORF1"
/product="NTPase"
mat_peptide 2067..2603
/gene="ORF1"
/product="p22"
mat_peptide 2604..3002
/gene="ORF1"
/product="VPg"
mat_peptide 3003..3545
/gene="ORF1"
/product="Pro"
mat_peptide 3546..5075
/gene="ORF1"
/product="RdRp"
gene 5059..6684
/gene="ORF2"
CDS 5059..6684
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ58888.1"
/translation="MKMASNDAAPSNDGAAGLVPEINTETLPLEPVAGAALAAAVTGQ
NNIIDPWIRTNFVQAPNGEFTVSPRNSPGEILLNLELGPDLNPYLAHLSRMYNGYAGG
VEVQVLLAGNAFTAGKILFAAVPPNFPVEFLSPAQITMLPHLIVDVRTLEPIMIPLPD
VRNTFFHYNNRPSERMRLVAMLYTPLRSNGSGDDVFTVSCRVLTRPTPDFEFTYLVPP
SVESKTKPFSLPILTISELTNSRFPAPIDSLFTAQNNNLNVQCQNGRCTLDGELQGTT
QLLPTGICAFRGKISADVQNSHQDRWHMQLTNLNGTPFDPTDDVPAPLGTPDFTGLLF
GVASQRNVGGTGNNTTRAHEVVIATTSTQFVPKLGSINFGSESDDFQVGPPTKFTPVG
IKVETGHPFRQWDLPNYSGALTLNMNLAPPVAPNFPGEQLLFFRSNVPCAGGVSEGII
DCLLPQEWIQHFYQESAPSQSDVALIRYVNPDTGRTLFEAKLHRTGYITVAHSGDYPL
VVPSNGYFRFDSWVNQFYSLAPMGTGNGRRRVQ"
gene 6684..7463
/gene="ORF3"
CDS 6684..7463
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ58889.1"
/translation="MAGAFIAGLTGDMLTSAVGSLANAGANAITQKIDFENNKQLQAA
SFQHDKDMLRAQVDATKQLQAEMIAIKQGILTAGGFSPADAARGAVGAPMTKVLDWSG
TRYWAPNSTKTTSYSGQFTSTPVHTPNFNSKPRPPTKTQPSSSSSGSVYSLSTQSTSL
PGPSSSGSSVSSVSTQSTKLSSVSSMSRTADWVNQQRSLSPYMSGALNISHVTPPSSR
ASSSGTVSTVPKEVLDSWTSAFNTRRQPLFAHLRVRGESRV"
ORIGIN
1 ccgttgctgg caaaaacaac aacaacgaca acgcaaaatc ttcaagtgac ggattgtttt
61 ctaacatgtc tgtcactttt aagaaagccc tcggggcgcg gcctaaacag ccgcccccgg
121 gagaaacaaa gcaaatctct aaaccgccaa gaccgccaac accggaattg gtgaagagaa
181 tacccccacc cccacccaat ggcgaagacg agccaaaagt ggtgtacaag gtgggagaag
241 gtgtgtctgg gctgcctgac ttaacaactg tcacgcagcc tgacgcacga tgtacagcct
301 atagcgtccc cccgctcagt caaagagagg cgggtgacgc gaaggaacca ttacctggct
361 ccatcttgga gatgtgggat ggtgagatct atcattatgg gttgtacgtg gagcgtggcc
421 atgtgcttgg ggtgcacaaa ccacccgctg cgataagctt cgctaaaatt gagttaacac
481 cattgtctct ttattggagg gttgtttaca ccccccagta cctaatagct ccagacactt
541 tgaaggacct gaatggagaa tcattcccat acacggcttt tgacaacaac tgctatgctt
601 tttgctgctg ggttttggat cttaatgatt cttggctcag caggagaatg attcaaagga
661 ccactggttt cttcaggcct taccaggagt ggaacaaaaa gccattacca accatggacg
721 agcccaagat caagaaagtt gcaaacgccg tcctatgtgc tctctcttca ctcttcacca
781 gacccattaa agacatcatc ggcaagctaa agccaatgaa catccttaac atactggcaa
841 cttgtgactg gacatttgca ggcatagtgg aatcccttat tcttcttgct gaactctttg
901 gggtgttctg gacgccccca gatgtgtctg cgatgatcgc tcccttgctc ggtgatttcg
961 aaatgcaggg ccctgaagat cttgccgtgg agctcgtgcc cgtggtaatg ggagggatag
1021 gtctggtgtt gggattcacc aaggaaaaga tcggcaagat gctttcatca gctgcatcca
1081 cactcagagc ttgtaaagat ctaggggctt atggattgga aatactcaaa ttagttatga
1141 aatggttctt ccctaagaaa gaagaggcca acgagctggc catggtaagg gccattgagg
1201 atgctgtgtt agacctggag gcgatagaaa acaaccatat gaccactctc ctcaaggaca
1261 aagacagtct tgccacatac atgagaaccc tcgacttgga ggaagagaaa gcaagaaagc
1321 tctccaccaa atctgcatca ccagacatcg tgggcacaat aaactcactg ttggcaagga
1381 ttgcagcagc ccggtcacta gtccacaaag caaaagaaga gctgtcaagc agacaaaggc
1441 ctgttgtcgt tatgatatct ggcaggccgg gcatagggaa aactcacctg gccagagagc
1501 tggccaagaa agtcgcatca acactggcag gtgaccaaag gattggcctg gtgcccagga
1561 atggtgtgga ccattgggac gcctacaaag gagagagagt ggtgctgtgg gacgactatg
1621 gcatgagcaa ccccatacag gatgccctaa gactccaaga actggctgac acctgccctc
1681 taacacttaa ctgtgacaga attgaaaaca agggaaaggt gtttgatagc gatgccataa
1741 taataacaac caacctctca aatccagcac ccttagacta tgttaacttt gaggcctgct
1801 ccaggcgcat agacttttta gtgtatgcag atgcaccaga tattgagaag gccaagcgag
1861 atttccctgg ccagccagac atgtggaaag accattacag accagacttc tcacacatca
1921 agctccaact ggccccacag ggcggttttg acaagaacgg caacacccca cacggtaagg
1981 gtgtgatgaa gtccttgact gttgggtcat tgatcgccag agcctctggc ctgctccatg
2041 agagaatgga tgaatttgag ctacagggtc ctggtctgtc aactttcaac tttgaccgca
2101 acaaggtcgc tgccttcaga caactggcag ctgaaaacaa gtatggcatg ttggacacac
2161 tgagagtagg aaaccagcta aagggtgtca aaaccatgga tgagctgaaa cgagccatca
2221 ataacatcac catcaagaag tgcctgatag tgtacaatgg gtgcacctac accatggagt
2281 ctgatggacg tggcaaagtg ttagttgaca aagtgcaaaa cacaacagtt caaaccaaca
2341 atgagctcgc gggggccctg caccacctca ggtctgcaag aataagatac tatgtcaagt
2401 gcttccaaga ggcaatctac tccctactcc aaattgctgg tgcagctttt gtcacctcac
2461 gcatagtgag gcgcatgaac atctcaaacc tatggtcaaa gccacctgct gaagacaatg
2521 atgaatcaga ggacaaagga gggtgtccca aacccagaga tgaggatgag ttcaccgttg
2581 attccaaaga tatcaaagtg gaaggaaaga aaggcaagaa caaatctggg agaggaaaga
2641 aacacacagc tttctccagc aagggcctca gtgatgaaga atatgatgag tacaaaagaa
2701 tcagagaaga aagaaatggc aagtactcga tagaagagta tctccaagat agggacaggt
2761 attatgagga acttgccatt gctaaagcca ctgaggaaga cttttgcgaa gaggaggagg
2821 ccaaaatccg ccagaggatc ttccgtccta ccaggaaaca acggaaggag gagagagcca
2881 ctctcggact cgtcacgggg tcagaaatca ggaagaggaa tccggatgac ttcaaaccaa
2941 gaggaaaact gtgggctgat gatgacagga gtgtggatta taatgagaaa ataagttttg
3001 aagcaccacc aagcatctgg tcaagaatag ttaattttgg ttcaggctgg ggattctggg
3061 tgtcctcaag ccttttcata acctcaaccc acgtgatacc gaaggggatc acggaggctt
3121 ttggtgtgcc catcaatcaa atacaaattc acaagtcagg agagttctgt cgcctgaggt
3181 tcccaaaacc catcaggacg gatgtgagtg ggatgatctt ggaagaaggt gcccctgagg
3241 gaaccgtcgc aaccatcctt gtcaaacggc cgacagggga gttgatgccc ttggctgcta
3301 gaatgggaac ccatgccaca atgaaaatcc aagggagaat ggtgggtggc cagatgggca
3361 tgttgctcac cggctcaaac gccaagagca tggacctcgg cacaacacca ggtgattgtg
3421 ggtgccctta tatatacaag agaggcaacg actttgtggt catcggcgta cacaccgcag
3481 cagcacgcgg aggcaacaca gtcatatgtg ccacacaagg aagtgaaggt gaagccactc
3541 ttgaaggagg ggacaacaag ggtacttact gtggagcccc tatcctgggt cctggcaacg
3601 caccaaaatt gagcaccaaa acaaaattct ggagatcttc caatgcacca ctcccaccag
3661 gtacctatga gccagcgtac ctaggtggaa aagacccacg agtgaagggg ggtccgtcct
3721 tgcaacaagt catgagagac cagctcaagc ctttcactga acccagaggg aaaccaccaa
3781 acccaagtat tctggaatct gcaaagagaa ccatcattaa cgttttggaa caaactattg
3841 atccacccca aaagtggaca tatgcccagg catgtgcatc tcttgacaaa acaacttcca
3901 gcggttaccc acatcatgtt cgcaagaatg actactggag tggtgagaca ttcacaggca
3961 aactggcaga tcaagcttca aaggcaaatc ttatgtatga ggaaggaaaa cacatgacac
4021 cggtgtacac cgcggccctc aaggatgaac tagttaaaac tgacaaaatc tatggtaaga
4081 tcaagaagag gctactgtgg ggttctgacc tttccaccat gatccgatgt gctagggcat
4141 tcggtggcct catggaagaa ctcaaagcac actgcatcac tcttcctgtc agagttggca
4201 tgaacatgaa tgaagatgga ccaataatat ttgagaaaca ttccagatat aactaccatt
4261 atgatgcaga ctactcccgt tgggattcta cacaacaacg ggcggtgctt gcatcagcac
4321 ttgaaatcat ggtgagattt tctgctgagc cacaattggc acagatagtg gctgaggacc
4381 tgctctcacc aagtgtggtt gatgtgggtg atttcaaaat tacaatcaat gagggcctgc
4441 catccggcgt gccttgcacg tcccagtgga actcaatctc ccactggttg ctcacattgt
4501 gtgccttatc tgaagtgaca ggactaggtc ctgacatcat acaggccaac tccatgtact
4561 ccttctatgg tgatgatgaa attgtgagca ctgacataaa attggatcca gaaaagttaa
4621 ctgcaaagct caaagagtat ggcctcaagc ccactcgtcc tgacaaaact gaggggccat
4681 tggtgattag tgaagacttg aacgggttaa cattccttcg ccgcactgtg acccgtgatc
4741 cagcaggttg gtttggaaaa ctagatcaaa gctctatcct caggcaattg tattggacaa
4801 aaggacccaa ccatgaagac cccagtgaaa ccatgatacc acatgcacag aggcccgtac
4861 aactcatggc actactagga gaatcctccc tacatggacc ctcattttac agcaaagtta
4921 gtaaattggt tatatctgaa cttaaggagg gaggaatgga tttttatgtg cccagacaag
4981 agtcaatgtt cagatggatg aggttctcag atctaagcac atgggagggc gatcgcaatc
5041 tggctcccag ttttgtgaat gaagatggcg tcgaatgacg ccgctccatc taatgatggt
5101 gctgcgggcc tcgtcccaga gatcaacacc gagacccttc ccctggaacc agtggctggt
5161 gcagctcttg ctgcggctgt cactggtcaa aataatataa ttgatccctg gattagaaca
5221 aattttgtac aagcacccaa tggggagttc actgtttcac ctaggaattc cccaggagaa
5281 atcctcctaa atttagaatt aggtcctgac ttaaatcctt atttggcaca cttatctaga
5341 atgtacaatg ggtatgctgg tggagtggag gtccaggttc tcctagcagg gaatgcgttc
5401 accgctggaa agatcctctt cgctgccgta ccaccaaatt tcccagttga attcttaagt
5461 cctgcccaaa ttactatgct cccacatttg atagttgacg tcaggaccct tgaaccaatt
5521 atgatacccc tccccgatgt gagaaacacc ttcttccatt acaacaatag gccctctgag
5581 cgtatgcgtt tggtggccat gttgtacaca cccctgagat ccaatggctc aggtgatgat
5641 gtcttcacag tctcatgtag agtgttaact agacccactc cagattttga attcacctac
5701 ctagttccac cctcagtaga gtctaagaca aagcctttct ctcttcctat cttaaccatc
5761 tctgaattga ctaattcaag gttcccagca cccattgatt cattgtttac cgcccaaaat
5821 aacaatctca atgtccaatg tcaaaatggt cggtgcacac tagatggtga gttgcaggga
5881 accacccagc tgctcccaac tggaatatgt gccttcagag ggaaaatatc agcagatgtg
5941 caaaacagcc accaagacag gtggcacatg cagttgacaa acctcaatgg aaccccattt
6001 gatccaacag atgatgtccc agctccgctt ggcactcctg acttcacagg tctgctgttt
6061 ggagttgcaa gccaaagaaa cgtcggtgga acaggtaaca acactaccag agcccacgag
6121 gtagtgatag caacaactag cacacaattt gtgccaaaat tgggttctat taattttggg
6181 agtgaaagtg acgattttca agtgggccca ccaaccaaat tcacaccagt tggaatcaaa
6241 gttgaaaccg ggcatccttt cagacaatgg gacctaccta actattctgg agcactgacc
6301 cttaacatga accttgcccc acctgttgcc ccaaacttcc caggtgagca gctgctcttc
6361 tttagatcaa atgttccttg tgctggtggt gtcagtgagg gtattattga ctgcctgctg
6421 cctcaagagt ggatacaaca tttctaccag gaatccgctc catcccaatc agatgtggca
6481 ctgatcagat atgtcaaccc tgacacgggc cgcactctct ttgaggcaaa actccacagg
6541 actggttaca ttactgttgc tcactctggt gattatcctc ttgttgttcc ttctaatggc
6601 tattttagat ttgattcttg ggtaaatcaa ttttactcac tcgcccccat gggaactggg
6661 aatgggcgca ggagagtgca gtaatggcag gagcttttat agcaggtctt acaggtgaca
6721 tgctcacctc tgctgtaggc tcactggcga atgccggagc aaatgccata acacagaaaa
6781 ttgactttga aaataacaaa caacttcaag cagcctcctt tcaacatgac aaagatatgc
6841 tccgcgcaca agtggatgca actaagcagc tgcaggcaga aatgattgcc atcaaacagg
6901 ggatcttgac cgctggcggc ttctcccctg ctgacgcagc aagaggggct gtaggagcac
6961 ccatgaccaa ggtgcttgac tggtctggca cacgctattg ggcaccaaat tctaccaaaa
7021 caacaagtta ctccgggcag ttcacatcaa cacctgtgca cacaccaaat ttcaacagta
7081 aacccaggcc tcctaccaaa acccagcctt cttcttcttc ttctggtagt gtttatagtc
7141 tttcaaccca gtcaacttca ctccctggac cctcttcttc gggttcatct gtttcttctg
7201 tctcaacgca atcaacaaaa ttgagttcag tttcttctat gagtagaaca gcagattggg
7261 ttaatcaaca aaggagcctc agcccctata tgagcggggc ccttaatatt tctcatgtga
7321 cacctccatc aagcagggct tcaagttcgg gaacagtctc aactgtgccc aaagaagttt
7381 tggactcctg gacatctgca ttcaatacac gcagacagcc gctcttcgca cacctcagag
7441 tgagggggga gtcacgtgtt tagtgaaaag aatcaattag ttttaat
//