Typing tool
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Typing tool
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Complete norovirus genomes
| MW305516 | GII.9 | |
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| GII.P7 |
ORF1: 1..5063
ORF2: 5044..6657
ORF3: 6657..7424
LOCUS MW305516 7452 bp RNA linear VRL 06-JUL-2021
DEFINITION Norovirus GII isolate PNV011337 nonstructural polyprotein (ORF1)
gene, partial cds; and VP1 (ORF2) and VP2 (ORF3) genes, complete
cds.
ACCESSION MW305516
VERSION MW305516.1
KEYWORDS .
SOURCE Norovirus GII
ORGANISM Norovirus GII
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Picornavirales; Caliciviridae; Norovirus; Norwalk virus.
REFERENCE 1 (bases 1 to 7452)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Genome-wide analyses of human noroviruses reveal coexistence of
viral populations evolving under recombination constraints
JOURNAL Unpublished
REFERENCE 2 (bases 1 to 7452)
AUTHORS Tohma,K., Lepore,C.J., Martinez,M., Degiuseppe,J.I., Khamrin,P.,
Saito,M., Mayta,H., Nwaba,A., Ford-Siltz,L.A., Galeano,M.E.,
Zimic,M., Stupka,J.A., Gilman,R.H., Maneekarn,N., Ushijima,H.,
Green,K.Y. and Parra,G.I.
TITLE Direct Submission
JOURNAL Submitted (23-NOV-2020) CBER/OVRR/DVP/LHV, U.S. Food and Drug
Administration, 10903 New Hampshire Avenue, Silver Spring, MD
20993, USA
COMMENT ##Assembly-Data-START##
Assembly Method :: High-performance Integrated Virtual
Environment (HIVE) v. 2
Sequencing Technology :: Illumina
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..7452
/organism="Norovirus GII"
/mol_type="genomic RNA"
/isolate="PNV011337"
/isolation_source="feces"
/host="Homo sapiens"
/db_xref="taxon:122929"
/country="Peru"
/collection_date="16-Oct-2008"
/note="genotype: GII.9[GII.P7]"
gene <1..5063
/gene="ORF1"
CDS <1..5063
/gene="ORF1"
/codon_start=3
/product="nonstructural polyprotein"
/protein_id="QPJ58884.1"
/translation="FGSQNSVNDSTNTAPSDKEEVGAFSNIKVGFKKMLGVAPKGTKA
PNSEQHCPTVKIGTRTLAVPPEPPNGEDTVQFDAKSETVRGLPDLTTVQNEHENTPYT
VPPLSEREHRPATEPLPGTILEMWDGEFYHYSVYVSGGKALGVHKPPAAISLATIELT
PISLYWRPVYTPNYLVCPDTLKGLAGEKFPYTAFSNNCYNFCCWVLELNDTWLSRRSI
SRTTGFFKPYQSWNRKPLPTVDDGKIKKVANAILCALGSLFSKPIKDLLGKLKPLNLL
HLLASCDWTFAGIVETVILMAELFNVFWTPPDVSNFIASLIGDFELQGPEDLAVELVP
VVMGGIGMVLGFTAEKIGRMLSSAASTLRACKDLGNYALDILKLVMKWFFPKKEEKAE
METLRAIEDAVLDMEAIGNNHLTTLLKDKDSLTAFMKTLDLEEEKARKLSTKSSSPDI
VGTINAILARIAAARSLLHKAKEEMFSRIRPVVVMISGRPGIGKTHMARHLAKSIANT
MSGDQRVGLVPRNGVDHWDAYRGERVVLWDDYGMGNPVKDALTLQELADTCPVTLNCD
RIENKGKMFDSDVIIITTNLVNPAPLDYVNFEACSRRVDFLVYAESPEIEKVKRDFPG
QPDMWKDHFKPDFSHIKLTLAPQGGFDKNGNTPHGKGTMRSLTQGSLTARVAGLVHER
RDEFQLQGNDLQIYNFDTNRVSAFRKLAADNKYGIMETMRVGAALKNVKTLEDLKVAL
RDVKFNECEIIYKSSKYRVSSNGKGSVSVDKVEDQASQTANEVGSALLRLRQARARYY
VSCFQDLVYTLIQVAGASFVVNRISKRFCWERWVKPTETQETSDSEKEAAQGRWEIEP
KDAEPEGKKGKNKKGRGKKHTAFSSKGLSDEEYDEFKRIREERNGKYSIEEYLQDRDR
YYEEVAVARATEEDFCEEEEAKIRQRIFRPTKKQRKEERGVLGLVTGSDIRKRRPDDF
QPKGNLWADDTRSVDYNERLDFEAPPSVWSRIVPLGTGWGFWVSSNLLITTTHVLPKG
IKELFGVEIKQIQIHKSGEFCRFRFPRPIRPDVTGLVLEEGAPEGTVCSILVKRPTGE
MIPLAVRMGTHASMKIQGRTVGGQMGMLLTGANAKNMDLGTGPGDCGCPYIYKRGNDI
VVAGVHTAAARGGNTVICATQGQDGEAVLEGNENLGTYCGAPILGPGKAPKLSTKTKF
WRSSPDALPPGTYEPAYLGGKDPRVEKGPSLQQVMRDQLKPFTEPRGKPPRPAVLEEA
KKTVMNVLEQTIDPAKPWTYSQACASLDKTTSSGSPHHVRKNDHWNGESFTGPLADQA
SKANLMYEQAKHVQPVYTAALKDELVKTDKIYKKIKKRLLWGSDLGTMIRCARAFGGL
MDSMKASCIALPCRVGMNMNEDGPIIFDKHSKYRYHYDADYSRWDSTQQRNILASAME
VMVRFSAEPELAQVVAEDLLAPSQLDVGDFVISVQEGLPSGVPCTSQWNSIAHWILTL
SAMAEVSGLSPDVVQAHSCFSFYGDDEIVSTDINLDPMKLTQKLREYGLVPTRPDKTE
GPLVITEDLTGLTFLRRSIARDPAGWFGKLDQDSILRQLYWTRGPNHENPYESMVPHS
QRATQLMALLGEASLHGPQFYKKVSKMVINEIKSGGLEFYVPRQEAMFRWMRFSDLST
WEGDRNLAPEGVNEDGVE"
mat_peptide <1..971
/gene="ORF1"
/product="p48"
mat_peptide 972..2069
/gene="ORF1"
/product="NTPase"
mat_peptide 2070..2588
/gene="ORF1"
/product="p22"
mat_peptide 2589..2987
/gene="ORF1"
/product="VPg"
mat_peptide 2988..3530
/gene="ORF1"
/product="Pro"
mat_peptide 3531..5060
/gene="ORF1"
/product="RdRp"
gene 5044..6657
/gene="ORF2"
CDS 5044..6657
/gene="ORF2"
/note="major capsid protein"
/codon_start=1
/product="VP1"
/protein_id="QPJ58885.1"
/translation="MKMASNDAAPSSDGAAGLVPEINHEVMAIEPVAGASIAAPVVGQ
QNIIDPWIRNNFVQAPAGEFTVSPRNAPGEFLLDLELGPDLNPYLAHLARMYNGHAGG
MEVQIVLAGNAFTAGKILFAVIPPGFPYENLSPAQLTMCPHVVVDVRQLEPVMLPMPD
IRNTFFHYNQDGGPKLRLIAMLYTPLRANNSGDDVFTVSCRVLTRPAPDFEFTFLVPP
SVESKTKAFTIPVLKISEMTNSRFPVPVDQMYTSRSEGIVVQPQNGRATIDGELLGTT
LVSPVSVCNFKGNLQTEVPGERQLYQLQLTNLDGSPIDPTDDTPGPLGCPDFTGLLYG
VASQRGPGDTTRAHEARIDTGNGTYAPKIGQVRFYSTSNNFEVNQPTHFTPVGIYIEG
NSSDFNQWQLPRYGGHLANNNHLAPAVSPLFPGEQILFFRSFIPGASGHTNGEMDCLL
PQEFVQHFYQEAATAQSEVALLRFVNPDTGRVLFESKLHKQGFMTIASSGDHPIIMPT
NGYFRFEAWVNQFYSLAPVGTGSGRRRIQ"
gene 6657..7424
/gene="ORF3"
CDS 6657..7424
/gene="ORF3"
/note="minor structural protein; small basic protein"
/codon_start=1
/product="VP2"
/protein_id="QPJ58886.1"
/translation="MAGAFIAGLAGDVLSSGVGSLVNAGSNAINQNVEYNFNRQLQEA
SFKHDKEMLNAQIAATTQLQKDIMAIKQGVLSAGGFSPTDAARGSVGAPMTKILDWNG
SRYWAPNSMRTTGYSGNFTSQGVRQVFQPVQGTPNPSTLKNVPKAPSSVSSLSTQSTQ
STKLSGSTAGTSIPSSRTTTLSRTSEWVRGQNERLSPFMSGALQTTFVTPPSSKSSSV
GTVSTVPKEVLDSWTPVFNTRRQPLFAHVRRRGESQI"
ORIGIN
1 cctttggcag ccaaaactct gtcaacgaca gtaccaacac cgccccttct gataaagaag
61 aggttggtgc attctccaat attaaagttg gattcaagaa aatgctgggt gtcgccccca
121 aggggaccaa agcacccaat agtgagcagc actgccccac agttaagatc gggaccagaa
181 cactagcggt tccccctgag cccccaaatg gtgaagacac cgtgcagttc gatgcgaagt
241 cagaaactgt gcgtgggtta ccagacctaa caacggtgca gaatgaacac gaaaacacac
301 catacaccgt ccccccattg agtgaaaggg aacacagacc agccactgag ccgcttcccg
361 gaacaatact agagatgtgg gatggtgaat tctaccacta ctccgtgtac gtcagcggcg
421 gcaaagccct aggggttcac aagcccccag cagcaataag cctcgcaacg atagagctca
481 cccccatatc cctctactgg agacccgttt acacccccaa ctacctggtc tgcccagaca
541 cgctgaaggg ccttgctggt gagaagttcc cctatacagc cttcagtaac aactgttaca
601 acttctgttg ctgggtgctt gagctcaacg acacgtggct tagcagaaga agcatctcca
661 gaactaccgg cttcttcaaa ccatatcagt cttggaatag gaaacccctt ccaactgttg
721 atgatggaaa gatcaaaaag gtggctaatg caatcctctg tgctcttgga tcactgtttt
781 caaaaccaat caaagacctg ttgggcaagc ttaaaccact gaacttgctg cacctgctcg
841 catcatgcga ctggacgttt gcgggtatag tggagacagt catactaatg gcggagcttt
901 tcaacgtctt ttggacaccg ccagatgtct ccaacttcat agcctccctg ataggtgatt
961 ttgaattgca aggtcctgag gacctggctg tggagcttgt tcctgtggtc atgggtggca
1021 taggaatggt cctcggcttc actgccgaga agataggccg catgctgtcg tccgccgcat
1081 caacactgcg ggcatgtaaa gacctaggaa actatgcact tgacatactc aaacttgtta
1141 tgaagtggtt cttcccaaag aaagaggaga aagccgagat ggaaaccttg agggcgatcg
1201 aggatgccgt cctggacatg gaagccatag ggaacaacca tctcacaacc ctcctcaagg
1261 acaaggatag cctcacggct ttcatgaaaa ctctggactt ggaagaggag aaggcgagga
1321 aactgtccac caagtcgtcc tcaccagaca tcgttggcac tatcaatgcc atactggcca
1381 ggatagctgc tgccagatcc ctcctacaca aggccaaaga agaaatgttc agcaggatca
1441 gaccggtggt tgttatgatc tcaggcaggc ctggcattgg caaaacccat atggcaagac
1501 acttggctaa gagcatcgcc aacaccatga gtggcgacca gagagttggg ctcgtcccgc
1561 gcaatggggt cgaccactgg gacgcctaca ggggagagag ggtggtcttg tgggatgact
1621 atggcatggg aaaccctgtc aaagatgctc taacactgca agagttggcc gacacctgcc
1681 cggtcaccct aaactgtgat aggattgaga acaaggggaa gatgttcgac agtgatgtca
1741 ttataatcac gaccaatcta gtcaacccgg cgcccctcga ttatgtgaac ttcgaggcgt
1801 gttccagaag ggttgacttt ttggtctatg cagagtcacc agaaattgag aaggttaaaa
1861 gagatttccc cggtcaacct gatatgtgga aggaccattt taagccagac ttctcccata
1921 taaagctgac tctagccccc caaggcggat ttgacaagaa tggtaacacc ccgcatggca
1981 agggcaccat gcgatcccta acccaggggt ccctgactgc aagggttgca ggtcttgttc
2041 atgagaggag agatgagttt cagctccaag ggaacgacct tcaaatatac aactttgaca
2101 ccaacagagt ctccgcattt aggaaactgg ccgcggacaa caagtatggg atcatggaaa
2161 caatgagagt gggtgcggca ctcaagaatg tcaagacttt ggaagatctg aaagttgccc
2221 tgagggatgt gaagttcaat gagtgtgaaa taatttacaa gagctccaaa tatcgcgttt
2281 cttccaacgg taaaggttct gtctctgttg ataaggttga ggaccaagca tcccagactg
2341 caaatgaggt gggttcagct cttcttagac tcaggcaagc aagggccaga tactacgtca
2401 gctgctttca agacctcgtc tacacactaa tacaggttgc cggagcgtca ttcgttgtta
2461 acagaatctc caagaggttt tgttgggaga gatgggtcaa accaaccgag acccaggaaa
2521 cgagtgactc cgaaaaggaa gcagcccaag gtagatggga gatcgaaccc aaggacgcag
2581 agccagaggg caagaagggc aagaacaaga aaggaagggg taagaaacac acagctttct
2641 ccagcaaggg cctgagtgat gaagagtatg acgagttcaa gagaattagg gaagaaagga
2701 acgggaaata ctccattgag gaatacctgc aagatcggga ccgctactat gaggaggtgg
2761 cagtcgcccg ggcaacagag gaggacttct gtgaagaaga ggaggccaag ataaggcaga
2821 gaatcttccg ccctacaaag aaacagagga aggaagaaag gggggtgctt ggtctggtca
2881 ctggctcaga catcaggaag aggagaccag acgatttcca accaaagggc aacctgtggg
2941 cagatgacac caggagtgtg gactataacg agagacttga tttcgaggct cccccgagtg
3001 tctggtcgag aatagtccca ctgggcactg gatggggctt ctgggtctca tccaacctct
3061 tgatcacgac aacacacgtc ctgcctaaag ggattaagga actttttggg gttgaaatca
3121 aacagatcca aattcataag tctggagagt tttgcaggtt cagattccca agaccaatca
3181 ggccagatgt cacggggctc gtgttggagg aaggtgcccc agaaggcact gtctgttcca
3241 tactcgtaaa gagacctaca ggtgagatga tccccctggc agtgaggatg ggcacacatg
3301 catccatgaa aatacagggt agaaccgtcg gtggccagat gggaatgctc ctcacagggg
3361 caaacgcgaa gaacatggat cttggcaccg gtcctggtga ctgtggttgt ccctacatct
3421 acaaacgtgg caatgacata gttgtcgcgg gtgtccacac cgcagcagcc cggggaggca
3481 acactgttat atgtgccaca caggggcaag atggggaggc agtccttgag ggaaatgaaa
3541 accttggcac ttactgcggt gccccaattt tgggtcctgg caaggcgccc aaactcagca
3601 cgaagaccaa attctggcgc tcatcaccag acgctttgcc gccaggcact tatgaacctg
3661 cctacctggg aggtaaggac cccagagtag agaaagggcc atccctgcag caagtcatga
3721 gagatcaact aaaacctttc acagaaccca ggggcaagcc acctagacct gcagtcttag
3781 aagaagccaa aaagacagtg atgaatgttc tagaacaaac catcgaccct gccaagccat
3841 ggacttactc ccaagcatgt gcctcactgg acaagaccac ttccagtggt agcccccatc
3901 atgtcaggaa aaatgaccat tggaacggag aatccttcac cggccccctt gcagatcaag
3961 catccaaagc caaccttatg tatgaacagg ccaaacatgt gcagcccgtg tatacggccg
4021 cgctcaaaga cgagcttgtc aagaccgata agatctacaa aaagataaag aaaaggctct
4081 tatggggttc ggatcttggc acgatgatca ggtgcgccag ggcctttggc ggtctcatgg
4141 acagcatgaa ggcaagttgt atagccctcc catgcagggt gggaatgaac atgaatgagg
4201 atggtcccat catatttgac aaacactcta agtacaggta ccactatgac gcagactact
4261 ccaggtggga ttcaactcaa caaaggaaca ttctcgcatc cgccatggaa gtgatggtgc
4321 gattctcagc cgaaccagaa ctggcacaag tggttgcaga ggaccttctg gctcccagtc
4381 aactagatgt tggcgatttt gtcatctcag tccaggaggg tctgccatcg ggggtcccat
4441 gcacatcaca atggaactca atagcacatt ggatcctgac tttgagtgca atggcagaag
4501 tgtcaggtct ctcaccagat gttgtccaag cccactcctg tttctcattt tacggcgacg
4561 atgagatcgt cagcaccgat atcaatcttg accccatgaa gttaacacag aaactcaggg
4621 agtatgggct ggtccccacc cgacctgaca aaactgaagg tcctctcgta ataactgaag
4681 atctcaccgg cctaacgttc ctgcgtaggt cgattgcacg agacccagct gggtggtttg
4741 gaaagttgga ccaagactca atccttaggc agttatactg gacaaggggc cccaaccatg
4801 agaacccata cgagagcatg gtccctcatt ctcagcgggc cacacaactt atggcccttc
4861 ttggtgaggc ttcactgcat ggtccccagt tttacaagaa agttagcaag atggtcatca
4921 atgaaattaa gagtggtggt ctggagtttt atgtgcccag acaagaggcc atgttcagat
4981 ggatgagatt ttctgacctc agcacatggg agggtgatcg caatcttgct cccgagggtg
5041 tgaatgaaga tggcgtcgaa tgacgcagct ccatcgagtg atggcgcggc cggcctcgtc
5101 ccagagatca atcatgaggt tatggcaatt gagcctgtcg caggtgcatc aatcgctgct
5161 cctgtggtgg gacaacaaaa tattattgat ccctggataa gaaacaattt tgtacaggca
5221 cctgctggag aatttactgt ttcccctagg aatgccccag gtgagttctt gcttgattta
5281 gaattaggtc ctgatttgaa cccctatctg gcacatttgg caagaatgta caacggtcat
5341 gcgggtggta tggaagtgca aatagtacta gctgggaatg cgttcacagc tggtaaaatc
5401 ctgttcgccg tcataccgcc tggatttccg tatgaaaatt tgtccccagc acaactcacg
5461 atgtgccccc acgtcgtggt tgatgtaagg cagcttgagc ctgtcatgct gcccatgcca
5521 gacattagga acacattctt tcattataat caagatggtg ggccaaaatt gaggttgatt
5581 gctatgctgt acacccctct aagagctaat aattcaggtg atgatgtgtt cactgtttcc
5641 tgcagggttc taacaagacc tgcccctgat tttgaattta catttttagt tcccccctct
5701 gttgaatcaa agactaaggc attcactatc ccagtgctca aaatttctga aatgacaaat
5761 tcaagattcc ctgtaccagt tgaccaaatg tacaccagca ggagtgaggg gatcgtggtt
5821 caacctcaga acggtagggc cacaattgac ggagagctac ttggcactac tctcgtctct
5881 ccagtctctg tgtgtaattt taagggaaac ttgcaaactg aggtcccagg tgaacgccag
5941 ctttaccaac tgcagctgac caacctcgat ggttcaccta tcgaccccac tgatgacaca
6001 cctgggccac taggttgtcc agacttcact ggcctcctct acggggttgc cagccagcgt
6061 ggtccaggtg acactacgcg ggcccatgag gcacggattg acaccggcaa tggtacttat
6121 gctcccaaaa ttggtcaggt caggttctat tcaacttcaa acaattttga agtaaatcaa
6181 cccacacact tcaccccagt ggggatctat attgagggca attcttctga ttttaatcaa
6241 tggcaactcc ccaggtatgg gggtcatcta gctaataaca accatttggc acccgcagtt
6301 tctccccttt ttcctggaga gcaaattctt ttctttagat ctttcatccc aggagccagt
6361 ggtcacacaa atggagagat ggattgtctc ctgcctcagg agtttgtgca gcacttctac
6421 caggaagcgg caactgcgca gtcagaagtg gccttactga ggtttgtcaa ccctgacact
6481 ggaagggttt tgtttgagtc taaactccat aagcaaggat tcatgacaat tgcaagttca
6541 ggtgatcatc ccatcatcat gccaactaat ggttatttta gatttgaagc ttgggttaac
6601 caattttatt ctctcgcccc tgtgggaact ggaagtgggc gcagaaggat ccaataatgg
6661 ctggagcttt tatagcagga ttggctgggg acgtcctgtc ctctggcgtt ggttcgctag
6721 tcaacgcggg ttccaacgcc atcaaccaaa atgttgaata taatttcaac aggcagctcc
6781 aggaagcatc tttcaaacat gataaggaaa tgctcaatgc ccagattgct gcgacaacgc
6841 agctgcaaaa agacataatg gcaataaagc agggggtttt gtccgctggc ggcttttccc
6901 caactgatgc cgcgagaggt tcagttgggg cccctatgac caaaatctta gattggaatg
6961 gatcaagata ttgggctcca aattcaatga ggaccactgg ctactctggc aacttcactt
7021 cccaaggtgt caggcaagtg tttcagcctg ttcaaggcac tcccaaccca agtactttga
7081 agaatgttcc caaggctccc tcttcagtga gttctcttag cacccaatct acccaatcaa
7141 caaaattgag tggctccaca gcaggaacct ctattccctc atccagaact actacacttt
7201 caagaaccag tgagtgggtg agaggacaga atgaaagact tagccctttc atgagcggcg
7261 cgctacaaac aacgttcgtg acgccaccat caagcaagtc ttcttctgta gggacagtct
7321 cgaccgtccc taaggaggtt ttggactcct ggacgcctgt cttcaacaca cgcaggcagc
7381 cactcttcgc ccacgttcgt aggcgagggg agtcacagat ttagtgaaaa gaatgatttg
7441 aatttgattc tc
//